LOCUS       DARYJX010000001        84004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYJX010000001 DARYJX010000000
VERSION     DARYJX010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..376
                     /locus_tag="TU257_000001"
     CDS             <1..376
                     /locus_tag="TU257_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL0833075.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TU257_000002"
                     /pseudo
     CDS             692..933
                     /locus_tag="TU257_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TU257_000003"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TU257_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL0833076.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TU257_000004"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TU257_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL0833077.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TU257_000005"
     CDS             6494..6823
                     /locus_tag="TU257_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0833078.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TU257_000006"
     CDS             6827..7261
                     /locus_tag="TU257_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL0833079.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TU257_000007"
     CDS             7263..7547
                     /locus_tag="TU257_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0833080.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TU257_000008"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TU257_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU257_000009"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU257_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL0833081.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TU257_000010"
     CDS             10025..10675
                     /locus_tag="TU257_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL0833082.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TU257_000011"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TU257_000011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0833083.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TU257_000012"
     CDS             12073..12813
                     /locus_tag="TU257_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL0833084.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TU257_000013"
     CDS             12810..14528
                     /locus_tag="TU257_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0833085.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HPKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TU257_000014"
     CDS             14567..15655
                     /locus_tag="TU257_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL0833086.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TU257_000015"
     CDS             15670..16374
                     /locus_tag="TU257_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL0833087.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TU257_000016"
     CDS             16634..17122
                     /locus_tag="TU257_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL0833088.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TU257_000017"
     CDS             complement(17632..18105)
                     /locus_tag="TU257_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0833089.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TU257_000018"
     CDS             18246..18926
                     /locus_tag="TU257_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0833090.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TU257_000019"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TU257_000019"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL0833091.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TU257_000020"
     CDS             20440..20871
                     /locus_tag="TU257_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833092.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TU257_000021"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TU257_000021"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL0833093.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TU257_000022"
     CDS             22061..23554
                     /locus_tag="TU257_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL0833094.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TU257_000023"
     CDS             23571..24902
                     /locus_tag="TU257_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL0833095.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TU257_000024"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TU257_000024"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL0833096.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TU257_000025"
     CDS             26090..27082
                     /locus_tag="TU257_000025"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL0833097.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TU257_000026"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TU257_000026"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL0833098.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TU257_000027"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TU257_000027"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL0833099.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TU257_000028"
     CDS             28261..29298
                     /locus_tag="TU257_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL0833100.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TU257_000029"
     CDS             29860..30474
                     /locus_tag="TU257_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL0833101.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TU257_000030"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TU257_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL0833102.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32842..33372
                     /locus_tag="TU257_000031"
     CDS             32842..33372
                     /locus_tag="TU257_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL0833103.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TU257_000032"
     CDS             33745..33978
                     /locus_tag="TU257_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL0833104.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TU257_000033"
     CDS             33953..34924
                     /locus_tag="TU257_000033"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL0833105.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TU257_000034"
     CDS             34934..35314
                     /locus_tag="TU257_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL0833106.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TU257_000035"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TU257_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL0833107.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TU257_000036"
     CDS             37633..37887
                     /locus_tag="TU257_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL0833108.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TU257_000037"
     CDS             38033..39394
                     /locus_tag="TU257_000037"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL0833109.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TU257_000038"
     CDS             39391..40473
                     /locus_tag="TU257_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL0833110.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TU257_000039"
     CDS             40474..41664
                     /locus_tag="TU257_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL0833111.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TU257_000040"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TU257_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL0833112.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU257_000041"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU257_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL0833113.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TU257_000042"
     CDS             44595..45266
                     /locus_tag="TU257_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL0833114.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TU257_000043"
     CDS             45279..45941
                     /locus_tag="TU257_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL0833115.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TU257_000044"
     CDS             45946..46203
                     /locus_tag="TU257_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL0833116.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TU257_000045"
     CDS             46200..46994
                     /locus_tag="TU257_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL0833117.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TU257_000046"
     CDS             47004..47759
                     /locus_tag="TU257_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL0833118.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TU257_000047"
     CDS             48030..50828
                     /locus_tag="TU257_000047"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL0833119.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TU257_000048"
     CDS             complement(51306..51608)
                     /locus_tag="TU257_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL0833120.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TU257_000049"
     CDS             complement(51670..52119)
                     /locus_tag="TU257_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0833121.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TU257_000050"
     CDS             complement(52279..54531)
                     /locus_tag="TU257_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0833122.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TU257_000051"
     CDS             54813..55043
                     /locus_tag="TU257_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL0833123.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..56463)
                     /locus_tag="TU257_000052"
     CDS             complement(55525..56463)
                     /locus_tag="TU257_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0833124.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            56805..57488
                     /locus_tag="TU257_000053"
     CDS             56805..57488
                     /locus_tag="TU257_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0833125.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            57490..58227
                     /locus_tag="TU257_000054"
     CDS             57490..58227
                     /locus_tag="TU257_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0833126.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            58671..60365
                     /locus_tag="TU257_000055"
     CDS             58671..60365
                     /locus_tag="TU257_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0833127.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            60477..61331
                     /locus_tag="TU257_000056"
     CDS             60477..61331
                     /locus_tag="TU257_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL0833128.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            61328..62182
                     /locus_tag="TU257_000057"
     CDS             61328..62182
                     /locus_tag="TU257_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL0833129.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            62466..63806
                     /locus_tag="TU257_000058"
     CDS             62466..63806
                     /locus_tag="TU257_000058"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL0833130.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            63784..63999
                     /locus_tag="TU257_000059"
     CDS             63784..63999
                     /locus_tag="TU257_000059"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL0833131.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            63999..64868
                     /locus_tag="TU257_000060"
     CDS             63999..64868
                     /locus_tag="TU257_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL0833132.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            64861..65688
                     /locus_tag="TU257_000061"
     CDS             64861..65688
                     /locus_tag="TU257_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL0833133.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            65675..66145
                     /locus_tag="TU257_000062"
     CDS             65675..66145
                     /locus_tag="TU257_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0833134.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            66163..67824
                     /gene="recN"
                     /locus_tag="TU257_000063"
     CDS             66163..67824
                     /gene="recN"
                     /locus_tag="TU257_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL0833135.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            68045..68917
                     /locus_tag="TU257_000064"
     CDS             68045..68917
                     /locus_tag="TU257_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0833136.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            69055..69906
                     /locus_tag="TU257_000065"
     CDS             69055..69906
                     /locus_tag="TU257_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0833137.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            69899..70741
                     /locus_tag="TU257_000066"
     CDS             69899..70741
                     /locus_tag="TU257_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL0833138.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            70719..71306
                     /locus_tag="TU257_000067"
     CDS             70719..71306
                     /locus_tag="TU257_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL0833139.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            71404..71679
                     /locus_tag="TU257_000068"
     CDS             71404..71679
                     /locus_tag="TU257_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL0833140.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(71740..72444)
                     /locus_tag="TU257_000069"
     CDS             complement(71740..72444)
                     /locus_tag="TU257_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL0833141.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(72755..73963)
                     /locus_tag="TU257_000070"
     CDS             complement(72755..73963)
                     /locus_tag="TU257_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0833142.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(74018..74911)
                     /locus_tag="TU257_000071"
     CDS             complement(74018..74911)
                     /locus_tag="TU257_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0833143.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            75280..75453
                     /locus_tag="TU257_000072"
     CDS             75280..75453
                     /locus_tag="TU257_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833144.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(75498..76433)
                     /locus_tag="TU257_000073"
     CDS             complement(75498..76433)
                     /locus_tag="TU257_000073"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL0833145.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            76676..77371
                     /locus_tag="TU257_000074"
     CDS             76676..77371
                     /locus_tag="TU257_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL0833146.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            77480..78001
                     /locus_tag="TU257_000075"
     CDS             77480..78001
                     /locus_tag="TU257_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL0833147.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            78396..78935
                     /locus_tag="TU257_000076"
     CDS             78396..78935
                     /locus_tag="TU257_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833148.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            79074..79844
                     /locus_tag="TU257_000077"
     CDS             79074..79844
                     /locus_tag="TU257_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL0833149.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            79956..82010
                     /locus_tag="TU257_000078"
     CDS             79956..82010
                     /locus_tag="TU257_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL0833150.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            82022..82618
                     /gene="recR"
                     /locus_tag="TU257_000079"
     CDS             82022..82618
                     /gene="recR"
                     /locus_tag="TU257_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL0833151.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            82766..83812
                     /locus_tag="TU257_000080"
     CDS             82766..83812
                     /locus_tag="TU257_000080"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL0833152.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        23630 a        15813 c        20143 g        24418 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctgagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcacccta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agcagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagat gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tcgccgcgtt gtccttgctc acctttttca ccgcgttgtc cttgctcacc
    55861 tttttcaccg cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc
    55921 accgcgttgt ccttgctcgc ctttttcacc gcgttgtcct tgctcacctt tttcaccgcg
    55981 ttgtccttgc tcaccttttt caccgcgttg tccttgctcg cctttttcgc cgcgttgtcc
    56041 ttgctcacct ttttcgccgc gttcgcctct gtcaccctta gggccggctg gtccttgttc
    56101 acctttagga cctgtttctc cggtttcgcc tttatctcca cgtggtccca taggcccaac
    56161 aggaccttgc tctccgcgtt cccctctagg tccggcaggc cccacaggtc cctgaggacc
    56221 acctttttta gcttgtagtt ctaagttttg taagtaggtt tgcatgaatt gtcttaatgt
    56281 atgtaggtat actcttactt cgccatctcc gagtccgtcc ctaattagtt cagctggatc
    56341 tggataggac tctaatcgcg tataatcttc agctcgggca tttccagctg ttcctaggct
    56401 ggccattgtt gctagggcaa tggctgctga gcagacgctg tacttgcgta ttgttttttt
    56461 catctttctc tcctttgatg atagtatcat tactttttca aaattctttc ccgaagaaga
    56521 gtttaacatg gtagcttgct atgagaaaca gctaggcgcc actttgtctc cgtagttttt
    56581 ttaattcaat gctgaatcgt ctgattttat cagagggtta ttgtttttaa aggcgaggag
    56641 ttgctttgct cagctagtct agcaagttca caggtcagct tatgtttctt atcaagcttg
    56701 tttgtttttg agaatatttt tcgataaaaa gatgttgtat taatattcat gttatagtat
    56761 aattatattc gttgccatga ctttatgaat gttaggagat aggaatggat tttacctttt
    56821 tacccaaata ctgggcttat ttcaattatg gtgtgcttgt aaccatgatg atttcagcct
    56881 gtgttgtctt ttttggcacg attataggtc ttttagtgac cctgataaaa cgcagtcata
    56941 tcaagccttt gtcttggctt gtcagtcttt atgtctggat ttttcgtgga acgccgatgg
    57001 tggtacagat catgattgct tttgcttggc tgcatttcaa cgatctgccc attgtaggct
    57061 ttggtgtgtt ggatttggat ttttcaagac tgcttcctgg tattattatt atttccttga
    57121 atagcggtgc ttacatatct gaaatcgtca gggctgggat tgaggcggtg ccaaaggggc
    57181 agctggaggc tgcttactct cttggtatcc gtcctaagaa cgccatgcgc tatgtgattt
    57241 tgcctcaggc ctttaagaat attttgccgg ccttgggcaa tgaattgatc accattatca
    57301 aggatagtgc cttgcttcag acgattggtg tgatggagct ttggaatgga gctcagtcgg
    57361 ttgtgacggc gacctatctg cctattacac ccttgctgtt tgcggccttt tattacttga
    57421 tgataacaac aatattgtcg caattattag gctgcttgga gcgcaagcta gcacagggag
    57481 ggagataaga tgactgagac agtgatttcg attcgtcagt tgcataagag ctttggcaag
    57541 catgaggtgc taaaaggaat agacctgacc attaatcagg gtgaggttgt ggtgattatt
    57601 gggccatctg gctcaggaaa gtccacgcta ttgcgcacga tgaatttgct tgaggtgcca
    57661 acaaagggac acatcagctt tgagggcgtc gatattacgg ataaggcaaa tgatattttc
    57721 aagatgcgtg agaagatggg catggttttt cagcagttta atctgtttcc caatatgaca
    57781 gtgctggaaa acatcaccct gtcacccatc aaaacaaaag gaatgtcaag ggctggcgcg
    57841 gagcagagag cttatgagct gcttgagcga gttgggctga gagataaggc tgctgcctat
    57901 ccggcaagct tatccggtgg tcagcagcag cgcattgcga ttgcgcgcgg cttggcaatg
    57961 gatcccgatg tgctgctctt tgatgagccg acctcagcgc ttgaccctga gatggtgggt
    58021 gaggttttgg ctgttatgca ggatttggca aaatcaggca tgacgatggt tattgtaacg
    58081 catgaaatgg gctttgccaa agaggtggcg gatcgcgtga tttttatgga cggtggtctt
    58141 gtgattgaag agggcagtcc agttcaggta tttgaagctc ctaaggagga gcggaccaag
    58201 gactttttga gcaaggtatt gtcatagctg gcgcagctaa agggcagcat gtcacctcaa
    58261 ggtctggcta ttagtcaatt ggctgtttgt tttgggcatt ttgtttgtaa aaggcttaga
    58321 aagtctggtt ggtgctgtag ccatatctgg ctttgctacg cttgggctgc tagctggtca
    58381 gtgggtatca tagtgattgg aggtgtggtc tctttattgg tcaacattgc tgtggcaggc
    58441 tagcacaggg gctttgcttg ttgtgctggg taaggggttt catttgcatg actgttaaca
    58501 ttgcttaatt gatgaattag gttgactttt gttttattgt ttgatactat tcaggtaagt
    58561 ctgtcattag aaagcgcttt gcttttttga tgatggaaat catgatcata tgatcacgtc
    58621 ttaggtaata tgttgttgtc aacatggtgg tctgaaagta ggaggataat atggactaca
    58681 aagctgttta tcaggagtgg ctgcacaatg attttttcaa tgaagaaatc aaggcagatt
    58741 tagaggcgat taagcatgat gaggctgaga ttcaagaccg tttttataag gtgcttgagt
    58801 ttgggacagc aggacttaga ggaaagctcg gtgctgggac caaccgtatg aatatttaca
    58861 tggttggtaa ggctgcgcag gctttagcta ataccattat tgatcatggg ccagaggcag
    58921 tctcacgcgg gattgccatc agctatgatg tgcgctataa gtctaaggaa ttcgcagaat
    58981 tgacctgctc gatcatggca gccaatggga tcaagtctta tatctacaag gggattcgtc
    59041 cgacaccgat gtgctcttat gcgattcgtg ccttgaactg tatctctggt gtcatgatta
    59101 ctgctagtca caatcctcag gcctacaatg gctacaaggc ttattgggaa gaggggtcac
    59161 agatcctaga tgacattgct aatcagatag cggttcatat ggacgctatt gagcgctttg
    59221 aggacgttaa gcagataccc tttgaggagg cattggcaag tggtctgacc agctatattg
    59281 atgatagtat agaggaggcc tataagaaag aggttttagg cttgaccatc aatgatactg
    59341 atattgataa gtcagtgcgt gtggtttata cacctttgaa tggcgttggt aatttgcctg
    59401 ttcgtgaggt attgaagaga cgaggctttg atcatgtctt tgtagtgccg gagcaggaaa
    59461 tgccagaccc agatttcaca acagttggtt atccaaatcc agaggtacca aaggcctttg
    59521 cttattcaga aagactaggg caagaagtag gagcagctat tctgattgcg actgatccgg
    59581 actgtgatcg tgtggcacta gaggttcgag ctgctgacgg tagttatgtc tttcttaatg
    59641 gtaataagat tggtgctttg ttgtcctact atatcttttc acagcgtcat gctaggcata
    59701 atcttcctga caatcctgtc cttgtcaaat caattgtaac aggggattta tcaaaagcta
    59761 ttgccgctaa atatgacgtt gaaacggttg agactcttac aggctttaaa aacatctgtg
    59821 gtaaggctaa tgactatgac atcacaaagg agaagaccta cgtctttggc tatgaggaaa
    59881 gcattggttt ttgttacggt acctttgtgc gtgataagga cgcggttagc gcctcaatga
    59941 tggtggtaga aatggctgcc tactacaagc aaaggggtca gtcactctta gatgtgcttc
    60001 aagacattta caaggaattt ggctattaca atgagcgtca ggtagcgcta gagctagagg
    60061 gtgttgaggg gcagaagcgt attgcacgta tcatggagga ctttagaaat gagcctattg
    60121 agcatgcagg tgctatgagc ttgaagacca ttgtagactt taaggacggc taccttgatt
    60181 ttccaaagca aaattgtttg aaatattatt ttgatgatgg gtcatggtat gcgctgagac
    60241 catctggaac agagcctaag atcaagcttt acatctatac tattggtgaa acagaggcag
    60301 acagcattgc taagctagac gctattgagt cagcttgtca agcaaagatg gacagtgtca
    60361 gctaattgtt caagctctgc aacagaaaat cagctaatca ataagcaaaa aggaaaagga
    60421 agtgacagtg cttccttttt tcgttataat agttaaaaaa ttagcaagga gtgcatatgg
    60481 tacagattat tgatgggaag gccctagcac agaaaatgca ggcagcattg gctaagaagg
    60541 tagagagctt aaaggcagaa aaaggaattg ttccaggcct tgttgtcatt ctggtaggag
    60601 acaaccctgc tagtcaggtt tacgtccgta ataaggaacg cgctgcctta gcagcaggct
    60661 ttaaaagtga aaccgttcgc ttgtctgatt cagtctgtca ggaagagttg atagagctca
    60721 ttgagcaata taatcaagat gatacgattc atggtatttt agtgcagctt cctcttccgc
    60781 accatattaa tgacaaaagc attatccttg ctattgatcc taaaaaggac gtcgatggct
    60841 ttcaccctat gaatacaggt catctgtggt caggtcgtcc gaatatggtc ccttgtactc
    60901 cggcagggat tatggagatg tttcatgact atggtatcga acttgaaggg aaaaatgctg
    60961 ttattgtcgg gcgctcaaat attgttggga agcctatggc gcagctactg ttggataaaa
    61021 atgctacggt aacgcttacc cattcgcgca cgcgccgact ggcagatatt tgtcgtcgtg
    61081 ctgatatctt gattgttgct attggtcagg ggcattttat cacaaaggag tttgttaaag
    61141 agggtgctgt tgttatagat gttggtatga atcgtgacgt caatgggcga ttgattggag
    61201 acgtcgcctt tgatgaggtg tcagagctgg ctagcatgat tactcctgtt ccgggtggtg
    61261 ttggaccgat gaccattact atgcttttgg agcaaaccta tcaagcagct ctaagaaggg
    61321 tgagtcaatg attatagatc aatcgtttgt tgctagggtt gttgttccgc ggcaggctga
    61381 ctcccataag gggagttacg gcagagtact gttagtaggt ggcttgtatc catacggtgg
    61441 tgctattatt atggtagcgc tggcctgtgt tcatagtggt gctggcctag taactgttgc
    61501 aactgataga gaaactattg ctgccttgca tagtcatttg ccagaggcga tggctattgc
    61561 ggtagatgat gaggaattac tgttatctca gctaggtatg gcagacctga ttttgattgg
    61621 tccggggctg tcggagaata gcagagcagc taggctgttt gaattggtcc ttgcacatgt
    61681 cgctgatcat caggtattgg tcattgatgg ctctgcctta aggcttttag cgaaaagggc
    61741 agctgatgtt aagcagctga ggtgccctct tgtgttaacg ccacaccaaa aggaatggga
    61801 ggcgctgtca ggtttagcga ttgatcagca gtatgatgct gccaaccaag cagctctcaa
    61861 gcattttcca agggctacga ttttggttgc taaaagctca gcaaccaaga tttatcatgg
    61921 caaccagatc taccggctaa gagtgggcgg accttatcag gctacaggtg gtatggggga
    61981 taccttggca ggtatgatag caggaatagc tgtccagttt ccagagtcaa gcttggtggc
    62041 taaggttgct tgtgcgacct atctgcactc tgcgattgct gatgagctgg caaagactgc
    62101 ctatgtggtt ttgccgactg ctattagcta tgagcttcct agatggctaa aggcaatcag
    62161 cacaggccag aagctaggtt gaggctgtgc tgcgaggtcg tttgggaaaa gcggttaatt
    62221 ggtaggcatg acagcagctg gtttcagtcg tttagctatt ttgagtttag agctgctagc
    62281 ttaagactgg gtgctgcttt atgattcaag gaagctatca ttggaaaaac ttgtgtcaag
    62341 ctgtagaagc cctagctggc ttcttttttt gtctcttttt tgctcactat ttatgtggaa
    62401 acatgatata attgcattag tatacagttg gagcagttag gcttcatgaa gtgaaaggta
    62461 aactgatggc agactattta tccgtcactc agctgacaaa atatttaaaa ttgaaatttg
    62521 atcgagaccc ttatctggag cgtgtctatc tcactggtca ggtatctaat ttcagaaaaa
    62581 gaccaaatca ccaatatttt tccttaaagg acgagggagc ggtgattcag gccaccatgt
    62641 gggcaggagc ttataaaaag cttggctttg atttagaaga gggcatgaag ctcaatgtgg
    62701 ttgggcgtat tcagctctat gagccaaatg gctcgtattc aatgatcatt gaaaaggctg
    62761 agccagacgg tattggtgct ttggcgctgc aatttgagca gctcaggcaa aagctggctg
    62821 gtgaaggctt ctttgatgag aggcataagc aggccctgcc gcaatttgtg acaaaggtag
    62881 gtattgtgac gagtccaagt ggggctgtga ttcgtgatat tatcacaacc atctcaaggc
    62941 gttttcctgg ggtgagtatt cttttgtttc caacaaaggt tcagggtgag ggggcagctc
    63001 aagaggttgc tgctaatatt actaaggcta accagcgtga ggatctggat ttgttgattg
    63061 ttggacgcgg cggtggctcg attgaggacc tgtgggcttt caatgaggaa atcgttgttc
    63121 aggctatttt tgagtctcgc ctgcctgtta tttccagcgt aggacatgag acagatacaa
    63181 ccttggctga ttttgtggct gatcgcagag ctgccacccc aaccgcagct gcagagctgg
    63241 cgacacctat tacaaaaaca gatattgtct cttggattgc tgagcagcag agccggtcct
    63301 atcaagcctg tctgcgctat atcagacaag ggcaggagcg ggtggataag ctttcttatt
    63361 ctgttatttt caggcagcca gagaggctct atgatgctta tagtcaacgc ttagataggc
    63421 ttacgacctc cttgatgacc acttttaaag agacattatc aggagctaag caggagcact
    63481 tgattttgga gcatcgttta gcctctgtca atgtacaggc aaggcttgag cgttatcagg
    63541 atcgtctggc aactgcgcat cgtctcttga tagccaatat gaccaatcaa tatgacagta
    63601 agctagcagg ctttgagcga gctcaagctg ccttgctgtc gcttgatacg agccgtatca
    63661 ttgcccgcgg ctatgccctg ttaaaaaagg acggtgtagt agctgcttgt gttaaggaca
    63721 ttaaaaaggg agatcatctt agtattatca tgcgtgatgg tcaattagaa gtagaggtag
    63781 aagatgtcaa cgaaaaaaat atttgaagag cgtttacaag aattagaggc tattgtgacg
    63841 aggctagaaa atggtgatgt gccactagaa gaggccatct ctgaatttca aaagggtatg
    63901 gtgctgtcca aggaccttca aaaaacctta caagcagctg aaaagacact tgttaaggtc
    63961 atgcaggcag atggcacaga gctagaaatg gatgcctaat ggataagcta acaagaatta
    64021 atgccacgat tcatcagtat tatgacaggc agtctactgt ttcagcagat ctggaggagg
    64081 ccattttata ttctgttgat ggtggaggaa agaggctccg tccactcatg ttattggagc
    64141 tgctagaggg ctttggtctt gccttgacag acgctcatta cgcggttgct gctgctgttg
    64201 agatgattca tacaggaagt ttgattcacg atgatttgcc tgctatggat aacgatgatt
    64261 accgtcgcgg gcgactaact agccacaagc aatttaatga agcaactgct attttggcag
    64321 gagatagtct ttttttggac ccttttgctc taatcgcagg ggcagatttg ccggctgacc
    64381 tgctggtgca attgattcag cagttttcct tagcgtcagg aacctttggc atggtcggtg
    64441 gtcagctctt ggacatgaag ggtgagcatc agctgctgga tattcaggag ctatctgata
    64501 ttcatgccaa taaaacaggg aaattgttga cccttccttt tgtggctgcg ggtatcatag
    64561 ctgagcagtc agcagacgtt ttgtcttgtc tgtgggaggc tggtaggctt gttggacagg
    64621 cctttcagat aagagatgat atattagacc ttacggctag ctttgctgat cttggcaaga
    64681 caccgcaaaa ggaccttgct gctgcaaaat caacctatcc gagtctgctt ggtttagagc
    64741 gctcaagggc tattttggag gagtctttga gtcaagcgct agctattttt agcagactag
    64801 aaagggaaga aggctttgag tctcaggcta ttatcaaaag gatcgagggg ttgcgactaa
    64861 atggctaaag aaagagtaga tgtgctagcc tatagacagg gactttttga aacgcgagaa
    64921 caggccaagc gcggtgtgat ggctgggcta gttatatcag ctataagtgg cttacgcttt
    64981 gataagcctg gtgaaaagat tgatgagggg atcgaactaa ggctcaaggg tgagaagctt
    65041 aagtatgtca gccgaggggg tctcaagctg gaaaaagcct tgcaggtctt tgggatctct
    65101 gtgcaggata aggtgacaat tgatattggt gcttcaacag gtggctttac agatgttatg
    65161 ctacaggcag gagctaggct ggtttacgct gttgatgttg gaaccaatca attggtctgg
    65221 aagctcaggc aggatagtcg tgttcgaagc atggagcagt acaattttcg ctatgcaaag
    65281 ctagcagatt tttcagaagg tcagccagcc tttgccagca ttgatgtgtc ctttatttct
    65341 cttagcctga tactgccgac attgcactgt attttgcagg aaggggcaga ggctgttgct
    65401 ctgatcaagc cacagtttga agcagggcgc gagcagattg gcaaaaaagg gattgtcaag
    65461 gatagactga ttcatgaaaa agtgattaag caggtggcag atactgctct taattgcgga
    65521 tttatcgtta aggggcttga tttttcgcct atccaaggtg gtcatggcaa tattgaattt
    65581 ttggctcatt tagtcaaggg aaagggctcc aaggctattg atgatcagct catacagagc
    65641 gttgttagca gtgcacataa ggaatttaaa cagcatgaaa aagagtgaac gattagattt
    65701 aataaaaaaa atggttttgt ctcatgagat tgagactcag catgagctat taaagctcct
    65761 agctgattat gggctagagc taactcaggc cactatttca agagacatga atgaaattgg
    65821 cattgtcaaa attccatctg gaactgggcg ttatgtctat ggcttgtcac aggatagtgg
    65881 caagcgggtg gtgcaaaggc ctgcctctat caaaaaaacg attttggaaa tgtctgaaaa
    65941 aacagcgggc ttggagcagc atattcacct caacgttgtt ccaggcaata gcaagctaat
    66001 caaacgttat ttgatgacag acttttcagg tcaattgttt agcctgattg cagatgatga
    66061 tagtttgctg ttgattgcaa aatcagaagc agacgctgat catatccgtc aggaattgtc
    66121 cctttggatg cagggattgg tctaaaaaat agagagaagc cgatgttatt agaaatttcc
    66181 attaagaatt ttgctatcat agaggaaatc tctttaaact ttgaaaacgg tatgaccgta
    66241 ctgactgggg agacaggggc aggaaagtcc attatcattg atgcgatgaa catgctgctg
    66301 ggtgcgcgcg caagcactga ggtgattcga catggtgctg ataaggcaga gattgagggc
    66361 ttcttttcgg ttgatgctaa tcctcattta gccgctgtgc tggcagaatc agggattagc
    66421 atggaagagg agttgattct tcgtcgtgat atttttgcta acggtcgtag cgtcagccgt
    66481 atcaatggtc aaatggtcac tgtcagcacc ctaaaaaaac ttgggcagtt tttagtggat
    66541 attcatggtc agcatgatca ggaggaattg atgcgtccac agctgcacca gcatattttg
    66601 gatagttttg gagatgaggc ctttgaccag ctcaagcagt cctatcagca gatttttgat
    66661 cgctataagg ctttgcgaag gcaggctctt gagaagcaaa aaaatgaaaa agaacatcag
    66721 gcgcgccttg acctgctggc ctttcagata ggggaaattg aggcagcaga tttggttaga
    66781 ggagaagatg acctgcttaa ccaagaaagg cagcgattgc tcaatcacaa aaagattgct
    66841 gataccttaa ccagtgccta cctttccttg gataatgagg acttttccag tctctcacag
    66901 gtccgctcta gcatgaatga gttgctgtct attgaggacc ttgccccaga gtatcagctt
    66961 atatcagctg gtgtgtcaga ggcttattat attcttgagg aggtcacaaa gcaattatct
    67021 gataccatcg accagcttga ttttgatgca ggcagattgc aggacattga gctgcgttta
    67081 gacagcatta atagtctgac aagaaaatat ggcggtggtg tgaatgatgt tttggactac
    67141 tatgccaata ttaccaagga ataccagtta ttaagcggag atgaccgttc ctctgatgag
    67201 ctagaaaggg aattaaaggt ccttgagaag caactggtga tgactgcctc acagctaagt
    67261 gacaagcgtc atgccctggc tctagagcta gaagccgaca tcaaagctga gctgagagag
    67321 ctttatatgg aaaaggcgga ctttaaggtc cactttacaa ggtcaaagtt taatcgagaa
    67381 ggcaatgaaa gcttagaatt ttatatctca accaatccag gtgagggctt taagccgctg
    67441 gttaaggttg cttcaggtgg tgagctttcc cgcttgatgc ttgctatcaa ggctgccatt
    67501 tctaaaaaag aggacaagac gagtattgtc tttgacgagg tggatactgg agtttcagga
    67561 cgtgtggccc aggccattgc taaaaaaata tataaaattg gcagctatgg tcaggtatta
    67621 gcgatttcgc atttgccaca ggtgattgct attgcagata accagtattt tatttccaag
    67681 gaaagcaagg aggagtcgac agtgtctaag gctaagctgt tgacacagga ggagcggatc
    67741 gaggagattg cgaagatgat tgcaggagct gatgtcacag agacagcaag aaatcaagcg
    67801 cgtgaattgc taggtaagga ctgagtatca tagcaaaagc agaacagtag ctttagagca
    67861 agcttgcctg ctgcacttgt cgctacatgt tcagaatgag ccacctgaaa ggcaagcaag
    67921 aaggctagct cttatgcgta tgctatcaga agctaagtct ttttgtctct tgcattggcg
    67981 agtgattgat tgataatatt atgataaata gaaggactaa aagaatactg actgaggagg
    68041 taaaatgctg aaaaaaagaa tgggcttggc tagtctgcta gtgttgatga cctttgtgta
    68101 tcagtgctgt tcagttactg ctgagcagta ttccgatact gaggttgagg tgctgcagat
    68161 tagcgaggag aaaagccaga tcatggaaaa tcaagaggcg cttaaagacc tcaccacgtc
    68221 gtctgatcag ctaaagaagg aagctttaaa gcctaaagag gcagctacca acaagagcaa
    68281 gcaagaggct tcgacagttt atttagctga ggacgatcct gtaaccattg atagctctga
    68341 cgaggaaagc aatcaagata tcatagcgga ttctgttcct gatttggtta ttaaaggtga
    68401 tcaggtggat gtatctgagg ttatggtctc tgtaaaggag gattcatcga aagttgctaa
    68461 gcaaagaact gacgcagcgc agcggtacag tatagccaag catcaattga cccaaaagct
    68521 tgaggccttt aatgcggcaa cggaccaatt gctgaccatg attgctaaaa aatctgattt
    68581 gactggtcag tattatgtgg ttgggcattc gttgggagaa atgctggctg ctcaaaatga
    68641 gaaaaagctt gctgagcaat tagtcatgca acaaaagcac aaaaaaggct taggctcatc
    68701 agtcactatt ttagacgaat taggacgtgt gatttctgac attagtggtc ataaaggcat
    68761 gcttcctttt aatcgtaaga tcagctttaa ggtacatcaa gtcagatacg atcttccact
    68821 aactggtgat cgaacagtgc tacctgccca gctggctggc ttactgcttt tactaatagg
    68881 tcttatgctg cctaaagtag ctaacaagaa aagctaagat atggtcttgg cttttttatc
    68941 ttttaagagg gtgagttttt gacagatgtt ttagctaaca ccaagagcta gataccagct
    69001 ttgctttatt tttaaaggag tgataaaata aagagacgat aaatgaggtt agaaatggaa
    69061 cttaagatgg gaactattaa aattgttgca gattcatcaa tgacgattga accagagcta
    69121 atcaaatctc ttgatattac ggttgtaccg ctttctgtca tgattgatag caagctgtat
    69181 tctgataatg agctaaaaga ggaagggcaa tttctacagc tgatgagagc tagtaagtca
    69241 ttgccaaaaa ctagtcagcc accggtaggg ctttttgcag atatttatga gcgattggtc
    69301 aaggaggggg cgacagctat tgttgccatt cacctctcac cagctctttc aggaacaatt
    69361 gaggcatcac gtcagggagc tgaaattgca gcagcaccag ttacggtatt ggactcaggc
    69421 tttacagatc aggctttgaa gtttcaggtg gttgaagcgg ctagactggc tcaagctggc
    69481 gctagccttg aggaaatcct tgaggcggta gaggatatta aacgaaagac agagctttat
    69541 ataggggtat cagcacttga gcacttggtt aaggggggac gaatcggtcg tgtgacaggc
    69601 ttgcttagct ccttgctgaa tattcgtgtg gtcatggaaa tgaaaaatga taccctgcaa
    69661 acacttgtta aaggacgcgg caataagacc tttactaaat ggctggatag ctatctagca
    69721 gaaaatagcc agcgacagat agctgaggtg gccatttcct atgctggtca gagggatttt
    69781 gctgatagcc tgaagaagac aatcgctacg gtctttgatg ggccaattac tgttttggag
    69841 actggctcaa tcattcaaac acatactggc gagggcgctt ttgcggtgat ggttagatat
    69901 gaataagcga gggtttttgg gaggccttat cttctttttc agtgtttttg ccttatcatt
    69961 tgtgatatta gctgtcctta ttccaaagtc tgacccacag ctgaagaaaa gtgattttct
    70021 aaaaaataag aagataagcc tcaattatat tgctattgga gactccttga cagagggagt
    70081 gggtgatctc accaaccaag gaggctttgt gcccttattg tctggtgatc ttggagacta
    70141 ctttaatgct accgttaata ctgaaaatta cggtgtttcc ggtaatacca gccagcaaat
    70201 tttaacgaga atgactgaga acaaggagat cacagagcag ctcaaaaaag ctaatctcat
    70261 gacattaacg gttggtggca atgatgtctt ggctgttatt cgcaagaact tagctaatct
    70321 taaggtatca agctttaaaa agccagcaag gcaataccaa gagcgcttac gcaaaatcct
    70381 tgatttggcc agaaaggata atcaggatct gccgatcttt gttttaggta tctacaatcc
    70441 tttttatttg aattttcagg agctaacaga aatgcagacg gtcattaatg actggaacaa
    70501 aaaaacacaa gaggttgttg atgactatga ccatgtttac tttgttccaa ttaatgatct
    70561 attgtacaaa ggagtagatg gtaaagaggg cattgtccag tcaacaggag agcaaacaac
    70621 gattgtgaat gatgctttgt tttcagggga tcattttcac cccaataaca caggctacca
    70681 aatcatgtca gacgcagtaa tggagacaat aagaaagaat ggaaaagaaa ttaaacctta
    70741 attggtggaa atgggctttt ttgctattat tggcttttaa tgcagccttt ttagcagtta
    70801 ttggaagtcg tattatacaa ataagagagc ctaagtctga gctgatcaat caaaaagcag
    70861 caaagaatat taaaataggg accttaacaa ccactaaaga gcaattaaat gaggcagtcg
    70921 ttagctacct aaaggatttt cagacggaaa aaatgaccta taaggtgtat gccacctcct
    70981 cgaccattct ctttgaagga acctatcagc tcttaggata tgaggtgccg ttatacattt
    71041 attttcagcc tcatcgctta accaatggtg cgatacagct gcaggttctc tccttttctg
    71101 tggggaccct ttctttgccg gaaaaggacg ttttgcaata cttgaaatcc agctataagc
    71161 tgccaaaatt cgttgaagtc ttacctaagc aatcggctat tattatcaat ctacagcaat
    71221 tggaaaatga tgccaacatc tatttaaagg ctcaaaagat tgatcttgtc aaggatgata
    71281 ttcgatttga catctataag aaatgagtct aactaacgtt taatacttga cctgtggctg
    71341 ttttttagat atgataatat ctgttaaagc gttaagctta ctaattattt ggaggattgt
    71401 taaatggcta acaaacaaga tttaatcgca aaggttgcag aagcaactga gcttacaaag
    71461 aaagattcag cagcagcagt tgacgctgtc ttttctgcaa tcgaagcttt tcttgctgaa
    71521 ggtgaaaagg tacaattaat tggttttggt aactttgagg ttcgtgaacg cgctgctcgt
    71581 aaaggtcgca acccacaaac tggtgaagaa attgaaattg cagcttcaaa ggttccagca
    71641 ttcaaggctg gtaaagctct taaggacgct gtaaaataat aaatcaaaaa aagccctatc
    71701 tcattaagct gtttagcctg tgagataggg ctttttccat taaggaagga gtcttgtttc
    71761 aataagtaat cttgtgtgat cgtctgaaag attagcgcca ataatttcta atgtgcactg
    71821 tcttgggaac aagagttcca tttcataagg ataaaatgag tagggctgta caaaagcagc
    71881 ctggctgcct tgagggacct gaattcttaa ttccactgag cgatgtggca tagcagcatt
    71941 tttgatggct gtagtactca taaagccttg ctttgtataa tgagtgcctg gcttgatcgc
    72001 tgataggatc tgcggatcaa aggtcttatc atggtagtaa cgagcgagtt cctcttcaga
    72061 agtgcccaat tctgttaaga atgtttcata aacatagcga tagacgatga tattccaagg
    72121 gatggttagc ttatgagtag cactatcaag taaggctaca gactgctgca gctgggcatc
    72181 caactggctg gtatctccca tcacctgttc tagggctagg ttaatagggc tggcagaggc
    72241 gtatgtatac tgatacatca tctttttttc tgcttctgta aaggctgttt gagacctcca
    72301 gcgattggtg ataatgtatt tggtaacatc aggctcacta aatttataat aaggcttaaa
    72361 gctattccca tagggctcaa aaacaactgt ttgtccttca tcataagact gtgccttgat
    72421 ggttgaaggc tgaacgacaa gcaacgataa gaaaaatgta aacaagcata gtgtacgaat
    72481 agctatcctt tgataagata actttgcgtt atgatgttga tgagtcattt agcttttcct
    72541 cctttacagt agtgccaaga gtgtcatcac ctaatgatga tgtctgttgc taacaggatt
    72601 agccttagtt gaaatgatta caaacttcct taatgtaaca aacataataa aaataaatta
    72661 tttttttatt atatattagt taagctcaga tgacaagcta tttgattttt ttctgagata
    72721 atgttacaag ggatttctaa caccaatgac taactcagat gaagggcttt ttcttggagg
    72781 attgcctata gttacaatag taggcaagac tggcagtcgc catgatacct attccaataa
    72841 cagcaaaggt tgctagatga acagaggctg gtatacaggt catgatggta gttgccagtg
    72901 gcattaagag aatagcagtt gtgacgattg agctaaagac tcgtcctagc aatgcctcag
    72961 gaactttttt ttgaacgata gaaaagaagt gaatgttaaa gattgttaaa aagcattcaa
    73021 accataaatt cccaagggca atcacaatga ctggaagctt caagagagcc atagctgtta
    73081 ttagaagcat ccctaggcca ctaaggccta gggataggag taagctttgc tgattatttt
    73141 taaagagctt gttagccata aaagctccta agatagcccc taaagctccc atcgaaagaa
    73201 gactagcata gcttgattgg ctgcctagca gctgattcga aaaaggaatt aaataattga
    73261 aagcagcaat aaagaaattc acaagagaag caataatcaa caaagaaaaa atgtcattgt
    73321 catggtagat gaattgcagc ccctccttaa tatctgttaa aagctgaagc ctattgcctt
    73381 ggctgctctg tttagtgatg tgcctttctt tgtccttgat tgtatataga catagaaagg
    73441 acaatagaaa gctaatgcta tctagagcca aggctgtttt gatgccaaag caatccatca
    73501 ctaaaaaagc aagcattggt gaggaaatac tgatgatttg agatacgatt tctagctgag
    73561 cattgaaatg aacaagtctt tctgtttcaa ctagtgtgac cacataggct cgaaaagcag
    73621 ttccagagaa ggcatacgat attgctaaaa gagcattaac agtgataagc ccataaagca
    73681 tgatagtagg gttagctatc agggctaaaa gtccgcagct gatagctccg atagcatctg
    73741 tccacaataa caattgtcgt cgtttataac gatcagcaat ggcgccaccg ataggattta
    73801 agatgagtga aataaggcct tcagctagct gataataacc caaatattgt cggccagttg
    73861 ctccgagtcc agcaatcccg ctgctgttgc tgtagtcgta aacagtattg cctattttgt
    73921 taatagctcg acttgcgagc agctggtagt cgtttttgcg catgataaaa cctccaaaag
    73981 attatgtggt tttattataa atcagttttt tagggtctta tgtttttttg caaataaggc
    74041 tagaggaggc tacaaatctt tcaaaatcct tttggtaatt gtgcgctagg tgaggacaat
    74101 ccaggctctc aaaaatggaa atagcagtag tcatatcctt aatgccagac aaacactgtc
    74161 ctctttggta gtcctctaag ccctttaaaa ataaaaagat ggttttttca tatagcttgg
    74221 tttcattatt gagtagggct agtatctgct tttgataata gcgcgcatag tcaagctgat
    74281 gtcggtggat acaggtttcc caaatattga gaagggtgat ggtaaccaaa tgcttattgg
    74341 ttgaaatgct ttcgtagtag gtatgattgt ttagaatttc ctttcccatt ttatctaata
    74401 agggaatatc aataaaaaga tagagatttc caattaaaat cagctcatag atatgccagc
    74461 tttcagtcct aaaaaggtag tcagtgacct catcaagata agccttagga aaaggaatgc
    74521 taggattgca tttacagata aagccttgga gtagaatgct gtttaaatag taacgattgg
    74581 tatcaggatc agcttggtgc tttgccaatt cctgcttttg cagctgcttg aatccctcaa
    74641 tatcgcgtgc atattccagc ttgatcagct gcgacatgaa ttgaatttgc tctgtctgtt
    74701 tgaagttggc agctatgtcc ataaattcgc tgatttccac ttgcatgctg tctaaagctg
    74761 ttaaaaactt tgttactgat agatcagatt cgccgcgttc aaagcgggat aactgagaca
    74821 aggacacgtc tttactggca agctgctgta aggtgatatt tctgttttgt ctaatgctgc
    74881 gaaatgcttt tcccaactga tgattagtca tattttttcc tcctctaatg agtatatcat
    74941 gtaaggcttc tgttgctgta ttttcccgta tgtgcaaacc ttgaaacttg tctgctgccg
    75001 ccacaaaggc atgaaaacat ttacactttt tgatagctat ttttatcatt gatgtagtct
    75061 ttttcgcaac atttgtacgg gatcatcaga ttaaaattaa gaaactgatg atgtgacact
    75121 gtaaacatgc taaaaatatg ttgaacaatg cctgtagctg gaaaatgggt acatgtattt
    75181 tcttcatgcc tgcgtcgtga cctgctgcta ttaaagcttg cttgaaaggg aaaaagagct
    75241 tataatagca gtgagaacat taaaaatgaa agtagagata tgccaataat tgttatcctt
    75301 ggacttgcta tcttttcggt ggttaaggtc attatttttc tatgctttta taaagcattt
    75361 gagaaaaaac aactaaagaa gctagaacag gatcaaaaag aaaccaagca ggcgattgac
    75421 caagaggagt caaaaaaagc ctttcccttt taacataaag ctagaaaaag tctgagacct
    75481 ttcgtctcag acttttttta aggcttatat tgtaattgac cacgaaaatc gtctagtgtc
    75541 tggtagccct tttcagccat aatgtcttgt agctccttag tgatacgctt aaaaatagct
    75601 ggaccttcct ggtgcagtgc tgttccaatt tgtaccatag ctgcgccgca taggatatgc
    75661 tcaaaggcat cacgtcctgt tttgacaccg cctgtgccaa tgatctgaat agaagagtta
    75721 agccgttggt aaaaggcatg aacattagcc agggcagttg gcttgatgta atcaccacca
    75781 ataccaccaa agccgttttt aggcttgatg acgacctgct catcatcaat aaccaagcca
    75841 ttgccaatgg aattaacaca gttggcaaag gctaaggggt attgattgaa aatggctgcg
    75901 gcttggtcaa aatggacaat atcaaaataa ggaggtagct tgatgcctag aggcttggtg
    75961 taataggaaa agatcttttt taggagctga tctgtggctt caaagtcata ggccagctga
    76021 ggcttacctg ggacattagg gcacgacagg tttagctcga caagtccttg ataatcagag
    76081 gcctgaatag cttttaggat agtctcggtt tcttcagcag acatgcccac aacagataaa
    76141 aagtggtgct tgcttgcttg atccttttgc atttctgtga caatatctaa ataatactgg
    76201 tagccatgat taggaagtcc cattgaattg attgagccaa gtgctgtatc tgcatagcga
    76261 ggctcagggt tgccctgtcg aggggctaga gtacctgttt ttgtcacaaa ggacccagcc
    76321 tcagaggcct caatggctag cagctcttcc ttggtcatgc aatacactcc agcagcgttc
    76381 atcaggcaat tattaaaggc aaatgtagcg atttttgtgg cagtagaaac catgttttcc
    76441 tccattttta gacaaatttt ttctattcta tcactagggc atgagaatag caaggcattt
    76501 ttgcaaaata cttgcttgaa ggctttcttt tgtgaggttt tagcgttttt catgatatta
    76561 acaaaatgat tttcaataaa gagaggaata gactagcttt tttgacctat tttttgtaaa
    76621 ataggagttg taaaaaggca agaagccttt aaacttaata aggagatatt aactaatggt
    76681 aaaattggtt ttcgctcgtc atggtgagtc agaatggaac aaagcaaacc ttttcactgg
    76741 ttgggctgac gttgatttgt ccgaaaaggg aacacagcag gctattgatg ctggaaaatt
    76801 gatcaaggaa gctggtattg catttgatct tgcctttaca tctgtgctta agcgtgctat
    76861 caagacaact aatcttgcac ttgagtattc tgatcagctt tgggtacctg ttgaaaaatc
    76921 atggcgcttg aacgagcgtc actatggtgg cttgactggt aaaaacaagg cagaagcagc
    76981 tgagcaattt ggtgatgagc aggttcatat ctggcgccgt tcatacgatg tgttgcctcc
    77041 tgatatggct aaagatgatg agcattcagc acatactgat cgtcgttacg ctcatcttga
    77101 tcattctgtt attccagatg cagaaaacct gaaggtaaca ctagagcgtg cccttccttt
    77161 ctgggaagat aagattgcac cagccttagt tgatggtaaa aatgtttttg ttggagcaca
    77221 tggtaactct attcgtgccc ttgtcaaaca catcaagcaa ttatcagatg acgagattat
    77281 gaatgtggaa atcccgaact tcccaccgct tgtgtttgaa tttgatgaca agctaaatct
    77341 tactgctgag tactacctcg gtggtgaata atgctgtgag gccagaccta gctctggctt
    77401 tttttgttat gtgataaaaa aggcgtttcc aacagaaatg tgatatgata gttaaaaagt
    77461 ggtaaaagaa gggaatctta tgaaagtaaa ggaacgccga gaagctatta cagataggtt
    77521 aagccaagca caagaagcca tctcagcaac tagcttagcc aaggcattgg gagttagtcg
    77581 tcaggtgatt gtcggagaca ttgccttact tagggcgcag cagcttgaca ttatttcaac
    77641 accaaaggga tatatcctgt caaatgcttt gtttagtcat cactattctg ctagaattgt
    77701 ttgccagcat ggacctgagc agacaaggca ggagttggag ttgatattag cacatgatgg
    77761 cattgtgacc aatgtggagg tagagcaccc tatttatggc atgctgacag caccgcttaa
    77821 cattaaaagc tcagctgata tcaataactt tattgaaaag ctcggagcct ctaaggcaga
    77881 attattgtcg tctttgacag agggtctgca cactcacctt ttgtcctgcc ctgatcagga
    77941 ggcatttgaa gagatcaaga gagatctagc agctgcaggc attctctatg gtgaacaata
    78001 atctgatagc agctggcttc acagggattt agtcttggct tgatagccaa tgtccctctt
    78061 ttgtcgtagg tgatagggac cgcaggacag ctcctagatg ctgaggccaa agtcttgtgg
    78121 ctgggcctca aatgaggtta aaagggaagg aagctgctat ggttatggtg aaagggctag
    78181 atttaccctt acttttttgc taggataatc ttttatgctg ttaggccgca gggcttggtg
    78241 ctgcaatggc tgagatgtgt ctgtcttttg tcttagcttt tggtgcttga gaagggctgg
    78301 gattgagctt atgctgtggt tgttttttga tttgctaggt gtcttgacat ctgtcgcgtt
    78361 tttggttata ctaacgacta gtaaaaggag atattatgac caaaaaacca acacaactga
    78421 ttgcctactc ttctattttg gtggcctttg ccatcttgat tccgatgata atgcccatta
    78481 agcttattat tggcccggct tcctttaccc tagctagtca tctgcccttg tttttagcca
    78541 tatttatatc cattccggta gcgatcttgg tggggatagg aacaggtctg ggctttttgc
    78601 tagcaggatt tcctatgatt attgttatgc gagccttctc acacgtgctt tttgcagcta
    78661 ttgcggcttt tatgctcaaa aggcagccta aatggctgga aacaccgtta agaacctttg
    78721 tttttgggat tatagcaaat gtgattcatg gcctagcaga gtttttagtg gtttatctga
    78781 tgacagcaac agcagcaact gatctttctt atttttggtc aatgctaatg cttgttggct
    78841 ttgggtcttt gctgcatggt atggtggatt tttatctagc cttatttatc tggcgcttct
    78901 taaggcagaa gggtcatcta tcagtgacaa gctaggattt ctgtgagtat ttatgtttta
    78961 gtagccaagg ctgttacagg ctgaggctct tttttctgaa agcgcttgca tttttttgaa
    79021 aaaatgctat actaaagagt gcgtttgtaa atatactaac aaaaggagat gtcatgaaaa
    79081 caccagaaca gatattagcc gcgacgatta cgattggtga gcataaggtt gcaaagcctt
    79141 ttttggctaa ggctatttta ggctttattg gcggtgcgat gattagtttg ggctacttat
    79201 tgtatgttag gattgcagct agtgggctgg agacctttgg cgctttttct agtattttgg
    79261 gtgcttgtgc ctttccgatt gggctgatca ttattttgat ggctggcggt gaattgatca
    79321 caggcaacat gatggcggtg tcggcagcct tttttgcaaa aaagattaag gccaaggact
    79381 tgatggccaa ttggctggtg attacccttt ttaatatttt gggagccttg ttcgttgcct
    79441 ttgtttttgg tcattttctg ggtctgacag ctactggcag ctttaaagaa gaggtcattg
    79501 aggtggccca tgccaagctt gctgcaactc ctctacaggc tattgtttca ggaattggct
    79561 gtaactggtt tgttggcctg gcgctttggc tgtgctatgg cgctagtgat gcgacaggta
    79621 agctccttgg aacctggttt cctgtgatga cctttgttgc ccttggtttt cagcatagtg
    79681 tggccaatgc ctttgttatt ccggcggcta tttttgaggg tggcgccagc tggatcgatt
    79741 ttgcgactaa ttttgctctc gtttatgtgg gcaatgtcct tggcggtgct atctttgtta
    79801 gtctctttta ttacaaggct tatgatcact ctaaggaagc ctgattagtg ctgttatatt
    79861 tttagactgg gagaccttat tctcagtctt atttttatat tttgtgataa aataggaaac
    79921 gacgtttaaa aaggaggagt tgataagcat ctaatatggc atcatggata aaaaagaaaa
    79981 aagcaagcat tcctaggcga attcatctcc tttttttggt gattgttttt ttgtttgttg
    80041 ccctgatttt gagattggca caaatgcaga tttatgagaa ggatttttac aaggcaaagc
    80101 tgacagcgtc aaccgtttac aaagtaaaaa gctctatgcc aaggggaacc atttttgacc
    80161 gtaatgggaa ggttctagtt tctaatcgta tcaaggacgt ggtaacctat acgagaagtc
    80221 ccaaggctag tgctaaggac attaaggctt tggctcatca gctagctgct tatattagct
    80281 atcctgaggc taaagtgaca gtcagagcca aaaaggatta ttatttggca gatccagagg
    80341 cttatgctaa gacggttcaa gccttacccc aaaaggacaa ggtggatcgc tttggtaata
    80401 aattagtcga agcacagata tatcaaaatg cggcagcctc tcttaaggaa acagacttga
    80461 cctattcaga ccaagagcta aaggttattg ctatttttaa ccaaatgaat gcagcagctg
    80521 tttttagcac tgtaaagctc aaaacatcag ccttatctga gcaggatatt gccatcatta
    80581 tggccaataa gtcaaaatta ccaggtattt cagttgggac agactgggag cgtcaggtgg
    80641 aggagacaag ccttgctgct attattggaa gggtctctag tgaggaagcc ggtcttccaa
    80701 aggaagaagc aaaggcttat cttaaaaagg gctattcgct taatgatcgt gttggaacct
    80761 cttatctgga aaagcaatac gaggaggtcc ttcaaggaaa gcatgaaatc agagaaatca
    80821 aaacgagcag atctggtgag gttatttcag ataaaatagt cgaaaagggt cagatggggc
    80881 ggaacctgaa gttgagcgtg ccacttgatt ttcaacaggg cgttgagcag atcttgaatc
    80941 agcacttcca gacagagctc aaaaatggtc aggctgctta ctcagaaggg atctatgctg
    81001 tggcgcttaa ccctaatacg ggagcgattt tagcgatggc aggtctatca cacaatccca
    81061 aaaccggtga gcttcaaaag gacgctttag ggactattac tgatgtgttt acacctgggt
    81121 ctgttgtcaa gggggcgacc ttggctgccg gctggcaggc tggagtgatt caggggaatc
    81181 aggtcttgat tgatcagccg attcaatttg gtggctccca gccgattaat tcttggttta
    81241 ccagcggtca gcaccctatt actgctagtc aggcgctgga atattcatca aatacttaca
    81301 tggttcaggt tgccttaaga atgatggggc aggattacgt gactggtatg accttggcca
    81361 atactggtat gaaggaaacc atgaaaaaat tgcgggcagc ctatgccgaa tttggcatgg
    81421 gagtggcaac tggcgttgat ttgcctggcg aatccagtgg ctacctcata gatcaatata
    81481 atactgcaaa tgttttgaca gaggcctttg gtcagtttga taactataca accatgcaac
    81541 tggcccaata tgtctcaact attgctaatg gcggcagtcg ccttgcgcct cacattgtag
    81601 aaggcattta tcaggataat gaccagtcag gaccaggtaa gctaagtaag gctattgaga
    81661 ctaccttgtt aaacaaggtg cacttagctg ctgatagttt agcgattatt caggacggtt
    81721 tttatcaggt ggtcaatagc ggtagtggct atgctacagg tagggctctt gcaggaggtc
    81781 ctgttaccat tagtgctaaa accggtaccg cagaaaccta tgctaaggat aaaaatggtc
    81841 aggctttatc tacctttaac ttgaatgttg ttgcctatgg tccgagtgct agtcctcaaa
    81901 ttgctgttgc tgtcatgtat cctcatgcga cagactctct agccaaggca catcaatacg
    81961 tggctaagga tatcattaat ttgtacatga agatgtataa aaaccaataa aggagaaacg
    82021 agtgctttac cctataccaa tcgcaaaatt aattgaaagc tattctaaat taccagggat
    82081 tggtgttaaa acagcgacaa gattggcttt ttacaccatt ggaatgtctg atgaggatgt
    82141 gaatgatttt gccaaaaatt tattagcagc taagcgagaa ttaacctatt gctctatctg
    82201 tggcaatttg acagatgatg atccctgcca tatttgcaca gatagcagtc gggataaaga
    82261 gatcatttta gttgttgagg attccaagga cgtttctgcc atggaaaaaa ttcaagaata
    82321 tcatggctat taccatgtgc tgcatggctt gatttctccc atgaatgggg ttggcccaga
    82381 tgacatcaat ctaaagagcc taatcacgcg tttgatggct ggagaggcaa cagaggtcat
    82441 tgttgcaacg aatgccacag cagatggaga ggcgactgcg atgtacatct cacgtctcct
    82501 aaagcctgct ggtatcaagg tgacgcgatt ggctagaggc ttggcagtag gatcagacat
    82561 tgaatatgct gatgaggtaa ccctgctgcg agcgattgaa aatcggacag aattatagct
    82621 tagcccattt tcagctctct gtcattagcc cttatgccat gtgataaggc cataaaggaa
    82681 ggcagatttt gtcagagtct tttgaaaagc aagctcgttt ttgttataat aagtggtagt
    82741 ctaattcaga tagggaaggt tatcaatgtc taaacaaacc ttaattttat tatacggagg
    82801 gcgttcggca gagcgtgaag tatcagtgct ttcagctgag agcgtgatga gagcagttga
    82861 ttacaccaaa ttttttgtta aaacctattt tatcagccag acaggtcagt ttatcaagac
    82921 acaggaattc tctagtcggc cgaccttaac agaaaggctg atgaccaacg acactattag
    82981 gctagagcag cagataaggc ctagtgatat ctacgaggag ggggctgttg tttttccagt
    83041 cttgcatggc cctatgggag aggacggttc tattcaaggc tttttagagg tgctaaaaat
    83101 gccttatgtg ggaactaata tcctctcatc aagtgttgca atggataaga ttaccaccaa
    83161 aagggtccta gagtcagctg gtatcccaca ggttgcttat accgtttata ttgaggggca
    83221 ggatttagac aggtgtctgg cagagactga ggcagtctta agctaccctg tgtttgttaa
    83281 gccggccaat atgggctcat ctgttggtat ttctaaggca gaatcagagg aggagttgcg
    83341 tgcagctatc ctgttggcct tgacgtatga cagtcgtatc ctgattgagc aaggggtttt
    83401 ggcaagagag attgaggttg gactgcttgg taataccgat gtcaaatcaa cccttccagg
    83461 agaggtagtc aagaatgttg acttttatga ttatcaggcc aaatacattg ataatgagat
    83521 cacaatggct attccggcag ctattgacga atcagctatg acaagcatgc gtacctacgc
    83581 agaaacagcc tttaaggcta ttggtgcttg tggcctgtcg cgttgtgatt tcttccttgg
    83641 tcaggacggt cagatctacc tcaatgaatt aaataccatg cctggcttta cgcagtggtc
    83701 catgtatccc ttgctctggg agcatatggg actgagctat gctgagctta ttgaggagct
    83761 agtcagatta gcacaggaaa tgtttgaaaa gcgtgaaggg catttaatat aagagacaaa
    83821 ggacggaagg agatatagca atcctctgtc ctttcgtttg gcctgattgg tagcgttttt
    83881 tggtcagaag cctttaaagc cctatcgtct acggttggct gtgccagctt tagcctgtct
    83941 atgaaggatc agcctgtagg cataaagtga aatagaaaga atattcctaa tatgttatgc
    84001 tata
//
LOCUS       DARYJX010000002        70403 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYJX010000002 DARYJX010000000
VERSION     DARYJX010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70403
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..351
                     /locus_tag="TU257_000081"
     CDS             <1..351
                     /locus_tag="TU257_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0833153.1"
                     /translation="RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKK
                     EPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGF
                     IASAGLLVFKRKKN"
     gene            877..1767
                     /gene="rapZ"
                     /locus_tag="TU257_000082"
     CDS             877..1767
                     /gene="rapZ"
                     /locus_tag="TU257_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL0833154.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            1764..2741
                     /locus_tag="TU257_000083"
     CDS             1764..2741
                     /locus_tag="TU257_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL0833155.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            2738..3649
                     /gene="whiA"
                     /locus_tag="TU257_000084"
     CDS             2738..3649
                     /gene="whiA"
                     /locus_tag="TU257_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL0833156.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            4009..5406
                     /locus_tag="TU257_000085"
     CDS             4009..5406
                     /locus_tag="TU257_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL0833157.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            5646..7196
                     /locus_tag="TU257_000086"
     CDS             5646..7196
                     /locus_tag="TU257_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL0833158.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
     gene            7467..8195
                     /locus_tag="TU257_000087"
     CDS             7467..8195
                     /locus_tag="TU257_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0833159.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            8207..9382
                     /locus_tag="TU257_000088"
     CDS             8207..9382
                     /locus_tag="TU257_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL0833160.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            9392..10387
                     /gene="lacD"
                     /locus_tag="TU257_000089"
     CDS             9392..10387
                     /gene="lacD"
                     /locus_tag="TU257_000089"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL0833161.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(10429..11148)
                     /locus_tag="TU257_000090"
     CDS             complement(10429..11148)
                     /locus_tag="TU257_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0833162.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            11288..13051
                     /locus_tag="TU257_000091"
     CDS             11288..13051
                     /locus_tag="TU257_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0833163.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKECYPQLS
                     FAEPMISSTMALESIKLSARVSLFKTIKNVSAIKKSFYPCNMEELDQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDEVPGFY
                     AYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYK"
     gene            13069..13554
                     /locus_tag="TU257_000092"
     CDS             13069..13554
                     /locus_tag="TU257_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0833164.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            13600..14481
                     /locus_tag="TU257_000093"
     CDS             13600..14481
                     /locus_tag="TU257_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0833165.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            14468..15286
                     /locus_tag="TU257_000094"
     CDS             14468..15286
                     /locus_tag="TU257_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL0833166.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            15290..15694
                     /locus_tag="TU257_000095"
     CDS             15290..15694
                     /locus_tag="TU257_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL0833167.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(15798..16058)
                     /locus_tag="TU257_000096"
     CDS             complement(15798..16058)
                     /locus_tag="TU257_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL0833168.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(16183..17115)
                     /locus_tag="TU257_000097"
     CDS             complement(16183..17115)
                     /locus_tag="TU257_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL0833169.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(17125..17553)
                     /locus_tag="TU257_000098"
     CDS             complement(17125..17553)
                     /locus_tag="TU257_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833170.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            17811..18836
                     /locus_tag="TU257_000099"
     CDS             17811..18836
                     /locus_tag="TU257_000099"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL0833171.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            18897..19343
                     /locus_tag="TU257_000100"
     CDS             18897..19343
                     /locus_tag="TU257_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL0833172.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            19672..19965
                     /locus_tag="TU257_000101"
     CDS             19672..19965
                     /locus_tag="TU257_000101"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL0833173.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            19946..21177
                     /locus_tag="TU257_000102"
                     /pseudo
     CDS             19946..21177
                     /locus_tag="TU257_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            21323..21670
                     /gene="rplS"
                     /locus_tag="TU257_000103"
     CDS             21323..21670
                     /gene="rplS"
                     /locus_tag="TU257_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL0833174.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            22185..22256
                     /locus_tag="TU257_000104"
     tRNA            22185..22256
                     /locus_tag="TU257_000104"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22218..22220,aa:Arg,seq:cct)
     gene            complement(22380..23183)
                     /locus_tag="TU257_000105"
     CDS             complement(22380..23183)
                     /locus_tag="TU257_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0833175.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
     gene            23811..24026
                     /locus_tag="TU257_000106"
     CDS             23811..24026
                     /locus_tag="TU257_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0833176.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            24023..24799
                     /locus_tag="TU257_000107"
     CDS             24023..24799
                     /locus_tag="TU257_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL0833177.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(24868..26124)
                     /locus_tag="TU257_000108"
     CDS             complement(24868..26124)
                     /locus_tag="TU257_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0833178.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(26210..27169)
                     /gene="nrdF"
                     /locus_tag="TU257_000109"
     CDS             complement(26210..27169)
                     /gene="nrdF"
                     /locus_tag="TU257_000109"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0833179.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(27314..29473)
                     /gene="nrdE"
                     /locus_tag="TU257_000110"
     CDS             complement(27314..29473)
                     /gene="nrdE"
                     /locus_tag="TU257_000110"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0833180.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(29494..29712)
                     /gene="nrdH"
                     /locus_tag="TU257_000111"
     CDS             complement(29494..29712)
                     /gene="nrdH"
                     /locus_tag="TU257_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL0833181.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            30134..30397
                     /locus_tag="TU257_000112"
     CDS             30134..30397
                     /locus_tag="TU257_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL0833182.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            30402..32135
                     /gene="ptsP"
                     /locus_tag="TU257_000113"
     CDS             30402..32135
                     /gene="ptsP"
                     /locus_tag="TU257_000113"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL0833183.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            32337..33764
                     /locus_tag="TU257_000114"
     CDS             32337..33764
                     /locus_tag="TU257_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0833184.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            34417..35631
                     /locus_tag="TU257_000115"
     CDS             34417..35631
                     /locus_tag="TU257_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0833185.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            35727..36296
                     /locus_tag="TU257_000116"
     CDS             35727..36296
                     /locus_tag="TU257_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0833186.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            36297..38249
                     /gene="gyrB"
                     /locus_tag="TU257_000117"
     CDS             36297..38249
                     /gene="gyrB"
                     /locus_tag="TU257_000117"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL0833187.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            38398..40122
                     /gene="ezrA"
                     /locus_tag="TU257_000118"
     CDS             38398..40122
                     /gene="ezrA"
                     /locus_tag="TU257_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL0833188.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            40492..40773
                     /locus_tag="TU257_000119"
     CDS             40492..40773
                     /locus_tag="TU257_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833189.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(40958..41413)
                     /locus_tag="TU257_000120"
     CDS             complement(40958..41413)
                     /locus_tag="TU257_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL0833190.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            41644..42951
                     /gene="eno"
                     /locus_tag="TU257_000121"
     CDS             41644..42951
                     /gene="eno"
                     /locus_tag="TU257_000121"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL0833191.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(43087..43323)
                     /locus_tag="TU257_000122"
                     /pseudo
     CDS             complement(43087..43323)
                     /locus_tag="TU257_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43532..43753
                     /locus_tag="TU257_000123"
     CDS             43532..43753
                     /locus_tag="TU257_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL0833192.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            43755..44015
                     /locus_tag="TU257_000124"
     CDS             43755..44015
                     /locus_tag="TU257_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0833193.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            44668..45273
                     /locus_tag="TU257_000125"
     CDS             44668..45273
                     /locus_tag="TU257_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0833194.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            45741..48521
                     /locus_tag="TU257_000126"
     CDS             45741..48521
                     /locus_tag="TU257_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0833195.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(48943..49080)
                     /locus_tag="TU257_000127"
     CDS             complement(48943..49080)
                     /locus_tag="TU257_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0833196.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      49324..49442
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            49440..49946
                     /locus_tag="TU257_000128"
     CDS             49440..49946
                     /locus_tag="TU257_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL0833197.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            50043..52001
                     /gene="ligA"
                     /locus_tag="TU257_000129"
     CDS             50043..52001
                     /gene="ligA"
                     /locus_tag="TU257_000129"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL0833198.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            52014..53036
                     /locus_tag="TU257_000130"
     CDS             52014..53036
                     /locus_tag="TU257_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0833199.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            53045..55345
                     /gene="pulA"
                     /locus_tag="TU257_000131"
     CDS             53045..55345
                     /gene="pulA"
                     /locus_tag="TU257_000131"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL0833200.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            55492..57371
                     /gene="glgB"
                     /locus_tag="TU257_000132"
                     /pseudo
     CDS             55492..57371
                     /gene="glgB"
                     /locus_tag="TU257_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            57438..58577
                     /locus_tag="TU257_000133"
     CDS             57438..58577
                     /locus_tag="TU257_000133"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL0833201.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            58567..59700
                     /gene="glgD"
                     /locus_tag="TU257_000134"
     CDS             58567..59700
                     /gene="glgD"
                     /locus_tag="TU257_000134"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL0833202.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            59697..61127
                     /gene="glgA"
                     /locus_tag="TU257_000135"
     CDS             59697..61127
                     /gene="glgA"
                     /locus_tag="TU257_000135"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL0833203.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            61146..63542
                     /locus_tag="TU257_000136"
     CDS             61146..63542
                     /locus_tag="TU257_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL0833204.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            63884..64081
                     /locus_tag="TU257_000137"
     CDS             63884..64081
                     /locus_tag="TU257_000137"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL0833205.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            64115..64831
                     /gene="atpB"
                     /locus_tag="TU257_000138"
     CDS             64115..64831
                     /gene="atpB"
                     /locus_tag="TU257_000138"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL0833206.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            64849..65343
                     /gene="atpF"
                     /locus_tag="TU257_000139"
     CDS             64849..65343
                     /gene="atpF"
                     /locus_tag="TU257_000139"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL0833207.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            65343..65879
                     /locus_tag="TU257_000140"
     CDS             65343..65879
                     /locus_tag="TU257_000140"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL0833208.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            65895..67400
                     /locus_tag="TU257_000141"
     CDS             65895..67400
                     /locus_tag="TU257_000141"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL0833209.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            67418..68293
                     /locus_tag="TU257_000142"
     CDS             67418..68293
                     /locus_tag="TU257_000142"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL0833210.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            68461..69867
                     /gene="atpD"
                     /locus_tag="TU257_000143"
     CDS             68461..69867
                     /gene="atpD"
                     /locus_tag="TU257_000143"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL0833211.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            69880..70296
                     /locus_tag="TU257_000144"
     CDS             69880..70296
                     /locus_tag="TU257_000144"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL0833212.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        20003 a        13438 c        16449 g        20513 t
ORIGIN      
        1 cgtggcgagc aaggaccaaa aggtgatcgt ggcgaacaag gaccaaaggg tgatcgtggc
       61 gagcaaggac caaaaggtga acgcggtgag caaggaccaa aaggcgatcg tggcgagcaa
      121 ggtccaaaga aggagccaga aaaagacacc aagccatcag tgccaaaggc accagataat
      181 atggctgcac caaaggctcc ggagaagaag aaccctaaag caccggctcc taagtcagct
      241 ccaaaggcat cattgccatc aacaggagac actagccaat catttgttgc agcagccctt
      301 ggctttatcg ctagcgcggg cttgctagtc ttcaaaagaa agaaaaacta agctagctaa
      361 agactgtaaa caagcctcaa ctgttacagc aagcctcttt gacatcttgc agataagagg
      421 atttcttagc gaatgaagtg tgtctaaagt cagatactct gctggactag cagtagctga
      481 tctccctgaa aatcagttat gctaaagcat tgagccttag ttgcaaggct taggtgtgac
      541 cttccaaagg aagctgcttt tgcctgtatc actttaggaa gatatctaaa agagacactt
      601 ttttcacgct gaagctaagc tagcttttcc tatgacaaat atcctataac aataaactcc
      661 aaacaaaaga gaggtcaaat ggtacctctc ttttacttag ctttaggatt gatagattct
      721 aaaggcttcc ttgtttcttg atcaagaagt ccttactgat agagtctgtc ttagccgggc
      781 ttatatggta taatacctaa tggagataag aaaagtcctt aacaaataga gtttcatcta
      841 ttgttacagg agcaaccaag tgaaaggaga tgctacatgt cagataaaca aatcaatttg
      901 gttattgtta caggaatgag tggcgccggc aaaacagttg ccattcaatc atttgaggat
      961 ttggggtatt ttactgttga taacatgcca ccagctttag tgcctaaatt tttagagctg
     1021 cttgagagga ccaatgaaac ccaaaaggtt gctctggtag tggatatgcg cagcagacgc
     1081 tttttcaagg agattaactc tatcttagat catattgagc taaatgccaa cctcaagcta
     1141 cggatcctct ttcttgatgc gactgatagt gagctagtgt cacgctataa ggaaactaga
     1201 agaagtcacc ctctggctgc tgatggtcgg gtgcttgatg ggattcgacg agaaagagag
     1261 ctgttagtcc cgcttaagag catgagtcag catgtggtca ataccaccga tctaacccca
     1321 agacagctgc gtaaggtgat ttcggatcag ttttcaagcg agtcagacca agcctcattt
     1381 agaattgagg tgatgagctt tggctttaaa tatggcctcc ccttagatgc ggaccttgtc
     1441 tttgatgtgc gctttttgcc taatccttat tatcaggtgg cgctaagaga gcagacaggg
     1501 cttgatcagg ctgtttttga ttatgtgatg actcatcaag agtcagaggc cttttataat
     1561 catttgttag gcttgattgt tcctattttg cctgcttatc aaaaggaagg caaatcagtg
     1621 ctaaccattg ctattggctg tacaggtggt cagcatagaa gtgtcgcctt tgcccatcgc
     1681 ttggcccaag acttgacagc agactggccg ctgcatgaga gtcatcggga catcaatcgt
     1741 cgtaaggaaa cggtaaatcg ctcatgagaa atcctaaaat aacggtgata ggaggaggaa
     1801 caggtattcc tgttatccta aaaagccttc gcaaggaggc ggttgacatt actgcggtgg
     1861 tcactgttgc tgatgatggt gggtcatctg gtaagctgcg caatgccatg cagcttaccc
     1921 cgccaggtga tttgcgcaac gtcttgttgg ccatgagtga catgcctaag ttttatgagc
     1981 gtgtgtttca gtatcgtttt aatgaggcag atggtgctct agctggtcat cctctaggca
     2041 atttaattat cgcaggtatt tctgagatgc agggatccac ctataacgct attcagattt
     2101 tgacgaaatt tttccatatc accggcaaga tttttccctc aagcgagcag cccttgacac
     2161 tgcatgctgt ctttaaggac ggtcatgagg tgtcaggaga aagctctatt gccagctacc
     2221 aaggcatgat tgaccatgtc tatgtgacca atacctacaa tgatgacctg ccaaaggcca
     2281 gtcgtaaggt ggttgaggcc attctccaaa gtgatatgat tgtgcttggt cctggttcct
     2341 tgtttacctc tattttgccc aatcttgtaa ttccagagat caaagaagcc ctgagagtaa
     2401 ccaaggcaga ggtggtttat atttgtaaca ttatgaccca gtacggtgag acagagcaat
     2461 tttccgatgc ggatcatgtt gcggttttaa atcagcatct gggcagggac ttaattgaca
     2521 ctgttttggt taatgttgag caggtgccaa aaagctatat gaattccaac caatttgacg
     2581 aatatctggt ccaagtagag catgactttg caggtctgtg taagaccgca aagcgtatca
     2641 tctcgtctaa ttttctgcgt ttggagaatg gcggagcctt tcatgacggg cacttggttg
     2701 tagaagaatt aatgaaccta gttaggataa ccaagctatg agttttacga caactgttaa
     2761 agaagaattg attcatttat ctgcttctga tcaaacagaa ttatcagcaa tcatcaagct
     2821 ggctggtagc ctaggcttgg ctaatcagag cttgaatttg tctatcacaa ctgaaaacgc
     2881 taagattgct cgctacatct atgcgcttat cgaagacacc tatcatatca ttccagaaat
     2941 caggtaccat caaaagacca acttgaaaaa aaatcgtgtc tatacggttt atttggataa
     3001 gcaggtggat aagctcttag cagatttaaa gctggcagat tctttttttg gcattgagac
     3061 aggtattgag cagcaggtca tgtcagatga tgatgctggt cgggcctatc tcaagggtgc
     3121 ttttttagcg gcagggactg taagggatcc agaatccggc aagtatcagc tagagatcta
     3181 ctctgtctat ctagaccatg ctcaggattt ggcccagctc atgcacaaat tcatgctaga
     3241 tgccaaggtt atcgagagaa aaaatggtgc agtaacctat ttgcaaaagg ctgaggacat
     3301 catggatttt ctcattatta ttggtgccat gtcgtgtaag gaggagtttg aggctgttaa
     3361 gcttttgcgt gaggcgagaa atgacatcaa tcgggccaat aatgcagaga ctgctaatat
     3421 tgctaaaacc atcaccgcca gcatgagaac cattaataat attatcaaaa tcatggatac
     3481 gattggctta gacagcctgc cagttgagct gcagcagatt gcccagatga gagtagccaa
     3541 cccagactat tctcttcaac aaatcgcaga ttcgcttgac tttgccatca ctaagagtgg
     3601 ggtcaaccat cgcctgcgaa aaatcaataa gctggcagag gatttataaa gacagcttag
     3661 cctttttcag gctgataaaa aagggggtaa ggtgatacga acaagccgcc ttttaaggca
     3721 tgccttgttg agctttctct aggctgttga tggagtgatc tcaaggcgct tttgttactg
     3781 tcattccaac aggctatctg attttgggat gacttcttac taataagctt ttctaatggc
     3841 tggctgacaa cgattagcga tatagttaag gcttatcgtg attcaacaag aggctttagt
     3901 ctcttttttg cttgtcagaa ttattttttt aggcttttct tacaaatgag aggacaatgt
     3961 gacaatctgt ggtatgatat tagtaatgaa tacaaaggag aacaaatcat gtcatgcaca
     4021 actattcttg tcggtaaaaa agcgacctat gatggatcaa caatcgttgc tcgtacagag
     4081 gattcacaaa atggggaatt tacccctaaa aaaatgacag ttgttagacc aaaagaccaa
     4141 cctagacact atcaatctgt cttgtctagc tttagcatgg agctgccgga tcagccgatg
     4201 gcttatacct cggtgcctga tgccctagga aaggacggta tctggggaga agcaggtgtc
     4261 aataccctca atgttgctat gtcagcaact gagaccatta cttcaaatgc tcgcgttctt
     4321 ggagcagatc ctcttgtttc ctctggtatt ggagaagagg acatgctgac cttggtgctt
     4381 ccttatattc ggtctgcaag agagggtgtt cttcgtttgg gagctatcct agaagcatac
     4441 ggtacctatg aggctaacgg tgttgccttt tctgatgagc atgagatttg gtggctggaa
     4501 acaataggtg gtcatcattg gattgcaagg cgcgttcctg atgatgctta tgtcactaat
     4561 cccaaccagt ttggccttga tcactttgaa tttaacaatc cagaggaata cctgtgttcc
     4621 aaggatttaa aggactttat tgccaaatat catctagatt tgacctatag caacgagcat
     4681 tttaaccctc gctacgcctt tggtagccaa agagataagg atcgccatta caatacacca
     4741 cgcgcttgga ttatgcagca atactttaat ccggagtttc tgcaggatcc gcgcagcttt
     4801 gaacttcctt ggtgccaaag acctgatcgc aaggtgacca ttgaagacgt taagtacgtg
     4861 cttagcaatc attatcagga caccccttat gatccttacg gcccagaggg aacgccgact
     4921 agtcgaaaat cctttaggcc gattggtatt aaccgtacga gtcaaactgc tattttacat
     4981 atccgtccca acaagcctaa ggaaattgct gccattcagt ggatggccta tggttcgatg
     5041 ccctttaata caatcgttcc gctattcacc caggtcaaga ccattccaga ttattttgca
     5101 aacactgttg aaaatgtttc cacagacaat ttctattgga ccaatcgctt gattgcagcc
     5161 ctggctgatc ctcacttcaa gcaccatgaa gcagatttgg aggactatct cgaaaaaaca
     5221 atggccaagg gtcatgccat gctgcatgct gttgaagcag cgctagtaaa aggtcagccg
     5281 gttgacctag aagaggccaa ccaaggcatg agtgatgaca ttcaggcaga tacacaggct
     5341 ctgctcaata agatcctctt tgatgctagc aatctcatga ccaaccgctt tagcctaagc
     5401 gactaagtaa tctcaatagt caaacgagct catatcatta tagatatggg ctcttagctt
     5461 gaaaaggata gtagagcggt cttatagtca gactaattaa tggtaacgat gagtccagtt
     5521 aaggtaaaaa aagagcactt agctaatgca aaaaaagtaa aaaacttgca aaagaatgat
     5581 attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata tatagaggag
     5641 gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt tttgcgggac
     5701 agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt accaccttct
     5761 atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg tctatgctga
     5821 tgaaagcagg aacagagcct catgattttg agccgtcaac aaaggacatc aaaaagatcc
     5881 aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtc cctgatatga
     5941 agaaatcact gacttctaag aaggttacgg tgattaaggg aacaggagat atgctattgg
     6001 tagctggctc tggtcacagc cacgagcatg accatgacga tgccgataaa aagcatgatc
     6061 atgaccacga cgaggaagga cacagccatg cttttgaccc gcacgtatgg ttgtcacctt
     6121 atcgcagcat caccgttgtc gaaacaattc gtgatggtct atctaaggcc tatcctgaca
     6181 aggctgacca cttcaaatct aatgccgctg cttatattga aaagctcaag gaattagata
     6241 aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact cagcacgcag
     6301 cctttggtta tatggcgctt gattatggct tgaaccaaat ctcaatcaat ggtgtcacac
     6361 cagatacgga gccttcagct aagcgcattg cagagctatc aaaatacgtc aaaaaatatg
     6421 acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa accctagcca
     6481 aggaggctgg tgtcaaatca gctgtcctta gtccgcttga aggcctaact gaaaaggaca
     6541 tgaaggccgg caaggattac tttaccgtta tgcgtgaaaa cctcaaaacc ctacgcttaa
     6601 caactgatgt agaaggaaaa gaaattcttc cagaagagga taccactaaa actgtttata
     6661 atggctactt taaggataag caggtcaaag accgcaaatt gtctgattgg tctggtaact
     6721 ggcagtctgt ttacccattc cttcaagacg gtacattaga tcaggtatgg gactataagg
     6781 ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac accactggct
     6841 atcagacaga tgtcagtcat atcaagatta atggtaagaa aaataccatg acctttgttc
     6901 gtaatggtga aaataaaacc tttacttata agtacgtcgg taaaaagatt ttgacctatc
     6961 caaagggcaa tcgtggcgtg cgcttcatgt ttgaagctaa ggagccagac gctggtgaat
     7021 ttaaatatgt tcagttcagt gaccatgcta tcgcaccagg taaggcggag catttccacc
     7081 tatactgggg tggtgacagc caagaaaagc ttcacaaaga gctagagcat tggccaactt
     7141 actatgatgc ggacctatca ggtcgtgccg ttgcccaaga aatcaatgct cattaaccac
     7201 tcaaaagact aggcagttca atcggcctag ttttttcttg tcttagttgc tgtataggac
     7261 ctaaatgctg atagctggtc ttaagattta tttttaattt ttctaactat atttaggttg
     7321 tatttgtttg ttaataccaa atccattgtt ttagggatta tatagaatta atatgttaaa
     7381 tattttaata tttttcaaaa aagtattgac ttttagattg taatataata ttatttaagt
     7441 ggttataata agttagaggt gttagtatga taaaggaaca gccactctac ttacaaattg
     7501 ttgatgtatt agaggtcaaa attagaaata ccatgtcagc taatgataaa ttgttatcag
     7561 aacgagagct aagtgactta tttggtgtta gtcggataac cattagattg gcacttaagg
     7621 agctagagct gcgtgggctt atttacaaac agcagggcaa ggggacctat gtatcaggca
     7681 taaaggagcc tgctacagac ctgtcctcag cctatagctt taccgaagag atgaaaaagc
     7741 aaggtcgtaa gcctcaaaca gtcattcttt catttgaaaa aatcaagacc acagcttact
     7801 tgtctggtat gttagattta gatgttgata ctgatgtttt tgagctagag cgtctaagga
     7861 ttgcagatgg aaagccatta atgtttgagc gcacttatat acctgaaagg ggatttgagg
     7921 cgataacgat tgatttattg gaaaaaaagc ccttatatga tgtgtttgct gaggattttc
     7981 aggaagctat ccgattggct gatgaggagt tttacgctag tatcgctcta gattatgaag
     8041 caaagctatt agggatcaaa aagggggatc ctgtgctgca tattatgcgt aagacctata
     8101 atgagaaaaa taggctaatc gaatttacct ttagtattgc tagagcagac cagtttaggt
     8161 accgtatcca gcaccaccct aacaagaaga tataggaggt aaggaaatgt ttacaaaaac
     8221 acaagcagaa ctagagctac ttggcgcagc tatcaccact agagaaatca agcagcagcc
     8281 agagctatgg tcagaggtct ttgagtcttt tctgaagcaa aaaaaagacc tcttagcctt
     8341 ttttgacagg attattgaaa gcgctaacag aaacaaggta aaaattattt ttacaggagc
     8401 tggaacttct gaatacattg gcaataccat ttgtcattat ttggagatga ctggtgacag
     8461 ggaaaattat ttatattaca gcattgcttc cacagacctt gttgcagctc caagccagta
     8521 tctctttgaa gaggatacag tcgtgcttgt ttcctttgca agaagtggca atagtcctga
     8581 aagtgtcgct gctgttagtc ttgttaatca gctggtgtca aatccttatc atttggtgat
     8641 aacctgtgcc aaagaggggg ccttagctca aaatgctaag aaggacaaaa ggagctattt
     8701 attcttgctg cctgaggcct caaatgacgc tggctttgct atgacgggaa gctttagctg
     8761 catgatgcta gcggccttgt tgatttttga tcaagcgcat tcccttgagg agaaaaaatg
     8821 ctatttagat cagattgtag gtatggtggc agctattatt cagcaggagg ctgatttaca
     8881 aaagctggtt agcttagagt ttcaacgctt ggtttacctg ggatcaggag ccttagcggg
     8941 gcttacgcaa gaggctcaat tgaagatttt agaattaaca gctggcaaaa ttgcaacagt
     9001 ctatgactcc tcaatgggct ttaggcatgg tccaaagtca tttattgatg atcagacatt
     9061 ggttattggt tttgttagca atgatcctta tacgagaagg tatgaccttg atgttttaga
     9121 agagataaga gaggatgcta ttgctgttga tacggttgca ttacagcagc aaggaggtga
     9181 gggctttagt gggcattgct ttggcttaga ctcgtcaatg ctattgccag atgcttattt
     9241 ggcctttccg cttgttttta tcgcccaaac gcttgctttg ctgtcgtcta ttaaggttaa
     9301 taatttacca gatactcctt cggccacagg aacggttaac agggttgtcc aaggtgttaa
     9361 gatttatcac tattttaagt aggagaacaa gatgtaccat ttatcaaaag ctaagtatcg
     9421 tcttcttgaa aaggtcagtc gtaagggcat catttcggcc ttggcctttg atcaacgcgg
     9481 ggttttaaag cgcatgatgg cagcccacca agacacagag ccaactcctt ggcaaatcga
     9541 agccctaaag gctctggtat cagaggagct aaccccctat gcctcctcta tcctgctaga
     9601 ccctgaatat ggcctgccag ccaccaaggt gcgtgatgag aagtctggct tattattagc
     9661 ctatgaacaa accggctatg acacaaccac cactagccgc ctgccagatt gtctggtgga
     9721 ctggtcagtc aagcgcctca aggaggccgg agctgacgca gtgaagttct tgctgtacta
     9781 tgatgttgat ggtgatgagc gtattaacca acaaaagcag gcctatatcg agcgtatcgg
     9841 ctcagaatgt caggcagagg agataccatt tttccttgag ctattgacct atgatgaggc
     9901 gataacagac aatcagagtg tagcttttgc caagctaaag gcacacaagg ttaatgaggc
     9961 catgaaggtc ttttcaactg agcgctttgg ggttgatgtc ctaaaggtag aggttcctgt
    10021 caatatggcc tatgttgagg gctttgcaga gggtgaggtt gtttacagca aagaggaggc
    10081 tatgcaggcc tttcgtgacc aagaggcagc tagtcacttg ccctatattt atttgagtgc
    10141 gggtgtatca gctagtctgt ttcaagagac cttggttttt gcggcagagg caggagctag
    10201 gttcaatggt gtgctgtgtg gtagggccac ttggtcagga gcagtagcgg tgtacatgtc
    10261 agagggcgag gaggcagcgc gtcaatggct tcgcacagag ggttttgaaa atattgatcg
    10321 tctcaatcag gtgcttgaga aaacagccag cccttggaca acaaagctta ctcttgatga
    10381 agcctagtaa aggcatgata aaagcaatac taggacattg cttctgtatt attggtaatc
    10441 actggaggac aaggcgtact tgaaaaattg ccaatgcttg taggactcgg tgtactctag
    10501 aatacggcca ttatctgtcg accgagtgag cttggtttga aggacacaag gagtgttgtc
    10561 tatcatgttt aaaaatgtag cgacatcttt aggcatgtga tccgtcagct gtgtttgctg
    10621 ggtgaagctt tgtgatcgca tttgaatgtg aaaatccaaa aagaagcgct tataaagcga
    10681 ctggtaatca gctaaatcac gctcagggca cagcaggtaa tcatgaggaa tataagatag
    10741 ctggtataaa tagggctgct gattaatcgt tcgtgtacgg gagatggtgt agtaaaattc
    10801 cgttttatga agtttcaaga gatttagata gtagggatca tttcccttaa ctacactaag
    10861 gacagtcacc tcctcttttt gatccttaaa ggtacctaga taggaaaatt ggactagctg
    10921 ttcttttctg gtacgggtaa tgaaggttcc aagtccctgc cttcttctga taaagccttc
    10981 tttttctagt tctttaaggg ctcgaatgat ggttatggag ctaacatgaa agcgtttaat
    11041 cagctcggct tcggtataaa atttgtcccc ggtatggtag tggccattca gaatttggtt
    11101 ttgcaattct tctttgatta gtcggtactt tgggtatttg atggtcatag ttactcactc
    11161 aataattgtt tagtacgatt atagcaaaaa tagtaagctg atgtcatatc ttaccagtta
    11221 ttgctcagat agcttgtcaa tcagtcattg atcaaaggct gatggttaat gaataaaagg
    11281 agataatatg aagcaatttt gcataaagga gcagttttac cttgatggca agccgtttaa
    11341 gatattatca ggtgccattc attactttag aatagctcct gatagctggt ctagggtgct
    11401 ttatcagctg aaggccttag gctttaatac agtagaaacc tatattcctt ggaatatgca
    11461 tgagccaagg aagggacagt ttacctttga ggggattgca gatgttgagg catttttgga
    11521 tttggcacag gaatgtggcc tatatgctat tgtcagaccc tctccttata tctgtgctga
    11581 atgggagttt ggtggtttac cggcttggct attaactgaa aattgtaggc tcagatcaag
    11641 cgatgaggtc tttcttaagc atgtatcaga ttattatgat gtgttactac caaagctggt
    11701 gaagcgtcag ttagataatg gcggcaatat tctgatgttt cagcttgaaa atgagtatgg
    11761 ttcttatggt gaagaaaagg cttatttaag aaaattaaaa gagcttatgc ttgctaaagg
    11821 cattagtgcc cctctcttta cctcagatgg gccttggcca gccacgctag catcagggag
    11881 tctgattgac gatgatgttt ttgtgacagg caactttggg tcaaacgctt caaagcaatt
    11941 tgccagtatg caggattttt tccaagcaca tcaaaagcaa tggcctctga tgtgtatgga
    12001 attctggttg ggctggttta atcgctggaa tgagccaatc attcgaaggg actccaagga
    12061 agctgttgat gcaatcatgg aagctataga gctaggcagc attaaccttt atatgttttg
    12121 tggtggcact aattttggct ttatgaatgg ctcgtcagct cgtctgcaaa aggatttacc
    12181 acagataacc tcctatgatt acgacgcatt actagatgag gcagggaacc cgacaaagaa
    12241 atataccctg ctgcaagaac gtctcaagga gtgttaccct caattatcct ttgcagagcc
    12301 aatgatcagt tctacgatgg ccttagagtc tatcaagttg tcggcaaggg ttagtctttt
    12361 taagacaatc aaaaatgtaa gcgctatcaa gaaaagtttt tatccttgta atatggagga
    12421 gctagatcaa ccaacgggct acctactgta tagaacgcac ctcgctagac atagcaagga
    12481 ggagcggctc agggtcattg atgctagaga ccgcattcag ctctttttag atgaaaagca
    12541 cgtgaaaacc cagtatcagg aggaaatcgg tcaggatata ctgatacatc aagagggtga
    12601 gaccacacag cttgatattt tagtcgaaaa tatgggacgt gtcagctatg ggtacaagct
    12661 gacagcacca agccaacaaa aaggattagg cagaggctta atggctgact tgcattttgt
    12721 aggtgattgg gagcattttc cactagattt tcaagagctg gattggattg atttttctgc
    12781 aggttggacc gatgaggtgc caggatttta cgcctatgat tttgattgtc agcagccggc
    12841 agatacctac cttgatttga gtcaattcgg aaaaggaatt gcccttgtaa atggtgttaa
    12901 cctaggacgt ttttggaagg tcggtccaac attatcgctt tatattccta agggactatt
    12961 aaaacaaggt caaaatagac tgctgatatt tgaaacagaa gggcagttta gtgagtcaat
    13021 tcgtttaact aaggaaccaa tttataaata gataaaagga gaaaacttat gacaattgtt
    13081 gcagcacgta ttgacggccg gttaattcat ggtcaggtag ctaatctatg gacgacaaag
    13141 ctaaacatta gccgtatcat ggtggtcgat aatgaggtga ttagcaatga ccttgaaaaa
    13201 acagcactga agctagccac acctagcggt gttaaattat ctatcttatc tgttgaaaaa
    13261 gcagccaaca atattttgga agggcgctat gattctcaac gcttgttgat agtagccaga
    13321 aagccggata gctttttgga gctgattcaa aaaggggttg ctatttcaga gttaaatgtc
    13381 ggcaatatgt cacagacacc ggagactcgt ccagtaacgc gttctattaa cgttgtagac
    13441 gaggatatag aggcattcaa ggctatttca gccaaagggt gtcatctcat tgcccaaatg
    13501 gtgcctaatg atgccccagc agactttatg ccgctgttgg ataaggttga ttaagatgtg
    13561 tcaaatcaaa aacgaatctg tttcaggagg taaaagctta tgattcaatg gtggcaaatc
    13621 ctattattaa cactctactc agcttatcaa atattagatg agctaacaat tgtctcttct
    13681 gcaggctcac ctgtatttgc aggatttatt tcaggtatca tcatgggaga tgtgcaaacc
    13741 ggtctttgga ttggtggtag ccttcaattg atggtgcttg gtgttgggac ctttggagga
    13801 gcttcgcgta tcgatgcaac ctctggtgcg gttattgcga cagccttctc ggttgctcaa
    13861 ggcatagagc cagaattagc gatttcaacc attgcagttc cggtagcggc cttgctggtt
    13921 tatactgata ttctaggacg cttttcaacg accttctttg ctcaccgtat tgaccgccat
    13981 gttgaaaact ttaactaccg aggcatcgag cgtgattacc ttatgggagc tgtaccttgg
    14041 gccctatcac gtgctctgcc ggtattttta gcggtctctt taggtggtgg tgcggttgat
    14101 acagttgtta agttcattga ccattatgaa tggctagcaa atggtctaac tcttgcagga
    14161 aaaatgcttc caggcttggg ctttgcgatc ttgcttcact acctaccagt taaacgtaat
    14221 ctccattatc tggctttagg ttttggcttg acagcaatgc taacaaccat ttacaccaac
    14281 cttcaggtag ctggaggcgc ccttgcagga gtagccaagg atttcaatgc cgcaccattc
    14341 aaggggctgc caatgattgg tattgctatt attgggcttt ccttggcaac cctccattat
    14401 aaaaatggtc aacaagcacc tgtagctgaa caaaaacctg gggtatcaga aagtggggaa
    14461 attgaagatg acgaaatcta attataaatt aaccaaacag gattttaatc aaatcaataa
    14521 gcgcagcctg ttcacattcc aatggggctg gaactacgag cgtatgcagg gctctagcta
    14581 tctttacatg attttaccac agcttcgtaa gatttatggc gatggaactc cagagctaaa
    14641 agaaatgatg aagacgcaca cgcagttttt taacacatca aatttctttc atacgattat
    14701 cacaggaatt gacttggcgt tggaggaaaa tgaaggactt gcctcaaaag atgctgttaa
    14761 tgggattaaa acaggcttaa tggggccatt tgctccaatt ggtgattcgg tctttggctc
    14821 cttagtacca gctattatgg gctctatagc cgcaggtctt gctaaagaag gggtttggtc
    14881 agggattact ggtgtattga tgtgggtatg tactcagatg atcatcaatg tgtttcgttg
    14941 gaagcagctt gaaattgctt ataaagaagg tacaaagctc gtcaccacca tgcgtgataa
    15001 gctaactgct gtagtagatg cagcctcagt catgggagta ttcatggtag gggccttaat
    15061 tgcaacaatg attaattttc agtttaccgc agcacccaaa attggagaga aagttatcaa
    15121 tattcaagat ttaattgata ccatttttcc acgtctagtt ccagccttat ttaccggagg
    15181 tatcttctgg ctgctagggc gtaagggcat gtcaccaact aaggcaattg ttgtgattat
    15241 tttatttgcc ttagtgatgt cttatttcaa tattttagga gtatagctga tggcgcaaac
    15301 cttaattctc attagtcatg gagctttttg tcgagagcta aaacagagta cagaaatgat
    15361 tatggggcca caggacaata ttttaacagc agagctgcaa ccaaacgaag gtgccgatga
    15421 ctttaaagaa aagcttttaa ggctaattgc aggtttagat gacgtccttg tgtttgcaga
    15481 tttgatgggt ggaacaccct gtaacgttgc cagtcgtttg ttaatggaag gacatcagtt
    15541 tgagctgtac gcaggcatga atatgccaat ggtcattggt ttcattaatg cctgtttgat
    15601 cggtgaagcg tttgatttca aagcctttgc ctgtgacaat attcaccatg tcaataccat
    15661 tatttcagct ctagcagatg atgatgacga ctaaccaagc tcgcttattt gtcacgcacc
    15721 ttacggagcg aaacggacca agagccgcat aatcaaaaaa gacactgcca aatcttggca
    15781 gtgtctttgc tgtaagctta ttttgctgcg tttgcgtctt tgagaccgta tttcttgttg
    15841 aaacgatcca cacgtccatc ggcttgtgta aacttttgac gacctgtgta gaatgggtgt
    15901 gagtctgatg aaatttctac acgaacaaga gggtaagttt ccccttcaaa ctcaatggtt
    15961 tctttagagg tcttagttga accgctaagg aatttgtagc ctgtagttgt atcaaggaaa
    16021 acaactggac gataatctgg atgaatgtct tttctcatct taaaaaagtt cctttctgcc
    16081 atgatactgt ccgtatcata gttattaact actctagttt aacaaaagtt agtaagcttg
    16141 acaagctttt tctatcacta ttcatcaata agatgataag tcttatgtta agagatcaat
    16201 cagctcttgg tagatttgct cattttcctc taagcctgat gacgtggcac cgctagcaag
    16261 agggtgcccg cctccttgat gacgcttagc aataccattg atgacctttt ctttactgcg
    16321 catgcgtact cggtactggc catctggcag ctcaacaaag ataacccaag cctgcaccac
    16381 gtctattttt ccaggagcag agacaatcgc tgagctttct gccaagctaa taccaaagga
    16441 atttaggacc tcctggctaa gcagtaggcg ggctgcacca ctgtcatcta tatcaagctg
    16501 ctcaaaaaca tagccttgta gcttggcaat tttaagtgga aaggaatcca tctgcctcga
    16561 aatagcagca aagtcaaagg cataatttct taattggctt gcaatggcca gtgttttact
    16621 gcttgttgag gcatagagaa agcgtcctgt atctcccaca atgccagtat ataatagtct
    16681 agctgcctca tcagttaaag ccaagccttg gctaaaggca aattcagcaa taatctcact
    16741 agcacttgag gtcttggtgt caacgtagga gagatcacca tagacatcat cgttagggtg
    16801 atgatcaatt ttaatgaggc aagcgcccat tgtgtagcgc tcatcatcaa tgcgggggcg
    16861 attggcagtg tctgtaacaa tcactaaagc ttccttataa tcatcgtcgg acacctgatc
    16921 catgagacta atccaagcca gactaggctc atcaaagcct gttatcagga cctttttgtc
    16981 agggaaatta tgcctgataa tctctttaag tcctgcttgg ctccctagag catctggatc
    17041 ggggttttgg tgccgatgaa tgatgatggt ttgatagtgc ttaatgtgtt ctaaaatagt
    17101 ttgaaacgtt gtcataggta tcctttagtt tttgatcata tcaatgtgag gaatattgtc
    17161 ttccagataa atctcagaga ctgctttaaa cccaaatgag ctgtaaaaag gctcaagata
    17221 agcctgcgct tgagcgtaga cgggaagctt tggaaagtgc tgttgacaat aggctaaggc
    17281 ttgatgaact aagtcacgtc ctagtcctgt tcgccttgca ttttgtgcta ccagtactcg
    17341 tcccagcttt atgctattgt cagttgggat taagcgacag taggccctaa gctctgaatc
    17401 aacctgcttg aaaagatgga tagctttttg atccaaatcg tcaatatcag gatagggaca
    17461 ttgctgctca accacaaaaa cagccacacg ctctttatag atggcaaaca attcatcttt
    17521 tgttaactga tcaaatgctt taacaaccca cattagctag cctccaaaat cactggtaca
    17581 atttccttta tgataacata atagcatata tcagccataa tggaacgaaa aaaacctgac
    17641 tcttaatgga cgatgtcgtg atgataatta catcttgtct caaaagctgg taatcatcac
    17701 aggcacagaa aaatgtgccc cttctgttgc tttttgagaa aaagttcact tgctttttgg
    17761 tagttttttg gtatcatact aaaaaataga cttaattaag gagatacagc ttggaaacaa
    17821 aagatttaaa gaagcttgct aaagctgagc tgcactgcca tttagacggt tctttgtcat
    17881 tagacactat tcgtcagttg gcggctttgg cgcaggtaga tgttcctcaa gatgattctg
    17941 agttaaagca gctggtaacc gcaccggaaa cctgtgaatc cttgatggat tatttaaaaa
    18001 cctttgatgt tatcagacca ttattacaaa cgcctcaggc tttaacattg gctgcttatg
    18061 atgttgtgaa gcaggctgcc cttgaaaatg tcatctacat tgaaattcga tttgctcctg
    18121 agttgtcaat ggatcagggc ttgaccgcca ctcaggtggt agaggcagtt ttaaaaggac
    18181 tcgagcaagg acaaaaagag tttggcattg tcgctaaggc tattgtgtgt ggcatgcgtc
    18241 agtcctcact agacattagc agagagattt ttgcaaatgt cttagagtgg gccaataaag
    18301 gcttggtagg ctttgatttt gcaggcaacg agctggactt tcctccagct gtcttagcag
    18361 atttgatcaa agagacgcag gcctatgggt taccatttac gcttcatgct ggtgagtgtg
    18421 gctgtccaaa ctatattgtt gatgctattg atttaggtat caaacgctta gggcatgtga
    18481 cggccattca taaccaaaag gatttattgg ccaagtttat cgccaatgat gtgacagcag
    18541 agctgtgctt cactagtaat ctacaaacca aggctgctag gactgttgag gactttcctt
    18601 atatgcagct aaggcaggct ggcgctaaat tatccattaa cacagacaat cgaacagtat
    18661 ccgataccaa tctgacaaag gaatatgaac tgtttgtcaa gcactttgag acaagcgtca
    18721 cagacttttt agagcataat cgtgatgcta ttaaggctag ttttgccagt ccggctgaaa
    18781 aagaagcttt attggatcgt ttggaaaagg cttatcagtc ttacatcaag aaataatgct
    18841 tttcttggca aagtatgata aaatatactg acatttagtt attttgggag gaaattatgg
    18901 cattagccaa aatcgtttat gccagcatga caggaaatac tgaagaaatt gctgatattg
    18961 ttgctaataa attgcaagaa ttgggacatg atgttgaggt tgacgagtgt acaacagttg
    19021 atgcttcaga gcttgaggct gctgatatgg caatcgttgc gacctatacc tatggtgatg
    19081 gggacttacc agatgagatt gtcgactttt atgaggactt gcaggatttg gatttgtcag
    19141 gcaagatcta cggtgtcgtg ggctctggtg atacctttta tgattatttc tgcaaatcag
    19201 ttgatgattt tgacgaacag ctcgctgcca ctggtgccac taagggagct gactcggtta
    19261 aggttgattt agctgctgag gaagaggata ttgctcgcct agaatccttt gctgagcaaa
    19321 tgtcacaggc attagaggca taagtaagac ttttgataca gattggtaaa acggtcagtg
    19381 gaggcttgcg ttttttacca ccaaatgcat gaaaaactga tattttctga tcgttttttc
    19441 atgactatgt gctctttttc aagaaaagtc atgccattat tagcctgaat gcaaacaatt
    19501 gatagtgtca aaatgttgat catatagtaa aaaaatgcat gtgactagaa agcagttaca
    19561 tgcattttcg tcatgcgttt gtcgtgaggc attttggggg ttacttgctt actgagctga
    19621 aattcactat aataaaaaga taaataaaga aaagaagaag ttaggtgaat gatgggatta
    19681 gagaccatac gacaagacat taatgctgtt gatcgtcagt tgattgcttt gctggaaaag
    19741 agaatggtct tggctgacca agtagcggcc tataagcagg tacatgatgt gccagtgctt
    19801 gatcaagagc gagaggctga ggtcctaagg agcgtgtcac agcagattcg gcataaggcc
    19861 tttgagcctg ccattcttga gctatttaag acaattatgg cagtatcaag gcgttatcag
    19921 gctgagcaaa tagcggttgg ttcaaatgat gatgaagcct attaaaaaca atcaagacat
    19981 cagtataggt gataatgtct atttggcttt tgcagccctg ctcgttgggg tggtggtagg
    20041 tgtgatagat actgtttttg gacaaggctt gttgctcttg tctgctgttc gtgatgctca
    20101 tctcatttac ctgttaccct gcttagctct tgctggactt gtgattgtgt tcttatatga
    20161 gcaatatggc caaatcgcta agcaggggat gggcttagtt tttgatgtgg ggaatggtga
    20221 aaaaacaaga ctaccactgg tgttgattcc gttgattatc ctctcaacct ggctgacgca
    20281 tttatgtgga ggcagtgctg gtcgtgaagg cgtagcggtt caaattggag cgacaggtca
    20341 catttttttg gacgtcttag acatcttaag gacaagtcac agctgttttt agtcatggga
    20401 atggccgcag gctttgcggg cttatttcaa acgccaatga cagcggttgt ttttgcctta
    20461 gaggtcctgt tgctaggaaa tataagctat ttagccttgc taccttctct tatagcagcc
    20521 tttaccgcct cttggacctc tcattgccta ggcttagaaa aattttcagt cccgatagcc
    20581 aaggccttga aaatcacccc gataaccttt gggaaattag tgctactagg ccttattttt
    20641 ggcttggctg gtaatctttt tgcctccttg ttagcaaggg ctaagccata cattgcagca
    20701 aggctgccaa atccttatta tcgtgtgttg cttgttggtg gttttctatc gcttagcctg
    20761 ctgctgtgcc attacgggcg ctatagtggc ctagggacta acttaattac agcggccttt
    20821 agtcatcagc ctattgctaa ttatgattgg ctattaaagc tcttgtttac cattatcact
    20881 ctctcggctg gctttcaggg cggtgaggtc actccacttt ttgctattgg tgcggcttta
    20941 ggaattgtcc tagcaccatg gcttggcttg ccggctcagt tggctgcagc ccttggctat
    21001 gctgcggtat ttggcagtgc caccaatacc tttttagccc cgatatttgt tggattagag
    21061 gtttttggtg caacaaacgc aactgcttac tttatcgtga tagcctttgc ttatatggtg
    21121 agccgaaggc attcaatcta cactaagcaa agggtgacca ctagcatcgc ttcctagtgt
    21181 cttggtcagt tttttggaga aaatagcttt acaagtgggg cttattttgt tacaataggc
    21241 tccgtgtgta atggacgcac aaaaattacg gctaatccgc taagactcgc gcttaagatt
    21301 agtaagataa ggagaataaa caatgaatcc attaattcaa agcttgacag agggtcaact
    21361 tcgtactgat attcctagct tccgtcctgg tgacactgtt cgtgtgcacg caaaggttgt
    21421 cgaaggatct cgtgaacgta tccagatctt tgagggagta gtcatttcac gtaaaagtca
    21481 aggtatctca gagatgtata ctgttcgtaa gatttctagt ggtatcggtg tagagcgtac
    21541 cttcccaatt cacacaccac gtgttgaaaa gattgaggtt gtgcgtcatg gtaaggttcg
    21601 tcgtgctaag ctttactacc tacgtgcctt gcaaggtaag gcagcgcgta tcaaggaaat
    21661 tcgtcgctaa aaagagcata cgagaggttt ttcactgtct tatgaaagga ctgctggagc
    21721 agcagggtct ttgggacaag ctttttttcg caggtatgtg aacctacgct caattcaaga
    21781 catatcaaag gctcattcta tgatagagtg ggctttttga ttgtgatcat gctttagtgc
    21841 ctaaataaat gacagcagcc tgactaatga aaggcttact tgactttgga aatgctcaag
    21901 gcttgcgcta ccagatagaa gctgacatca tgccatagca gtcaagggga agaaggacta
    21961 gattttttgg cgaggtgttg atctgtgacc ctgatgttgt tgggaatatg agagtaattt
    22021 aaaatttcgt cttgcattct acctttttct aggttacaat agacaagtaa cctgattagt
    22081 gaagctaaaa gacgtagcga tgggttctaa aaaagaatga ttctggcgtt tttggctaac
    22141 ctaagctgat agctttgcta ggcagtgtct tagtcatctg gtcagtcctg ctagtttaac
    22201 ggataaaaca agcgcctcct aagcgctagc tgtgggttcg attcccgcgc gggacattaa
    22261 aaacaaagta aaaagagtct gagaaggttt gagctgcccc taattgttag atttttttct
    22321 aactcttgaa gtgtgggtca aagactattt gtctcaggac tctttttaat tggtttttac
    22381 taagctgctt catctagttc ttcagttgct aagttgtttc cttcttctgt atgttggttt
    22441 tcatcaagta gcattcctgt gcggtaatct aatgctgcca aaggtgatac attatccaga
    22501 acaactgagg ttataccata atgatcaacg gattctttgt tgcctcccaa tttgatttgg
    22561 aggagctctc cgttttgatc aattccaacg tactgtaaca ctacttgacg aggaactaat
    22621 tcatcattct gataaatagg agttacctta taatctagcc aaaagttagg gtgtatggct
    22681 aaccaattgt ctagtctatt ttcataataa agcattccta aaggattttt atcactaaaa
    22741 cctgtattaa ggtattttgt catagtaact aaatttttgg gttcatcatt taggccgcta
    22801 aactgataac cgactagatg tccgcgatcc attaaccaag tctttttccc tctagaatta
    22861 atgacttgat agttatgcca gccgggagga ttaaatctaa gcgcttttct tttgagagtt
    22921 ggttcatctt gatctttgag ttgtatgtgt gcataggtgg ctctttgtaa atgatcaaga
    22981 tctcccagag ctatttggta ttttccagta aacggtaaaa ttcctggtat ttcggtagct
    23041 tttgttccca atgatatttc cgttgtatct gggaaggttc taagttttct tgcagattga
    23101 acagagttag ctgtgaaaat agtcagaata gttaacaaaa caattgttag acttttccag
    23161 ttacggcgac gtgatttaga catatcaatg ccctcctttt tttgtttacg agttaagtat
    23221 atcactttta attaaaaaaa cttaaaatta ataaaattat tttaattata atattcatct
    23281 aaattatctt tatttttaat tcaaaaatat aagcaattga ttcacataaa caaattgaga
    23341 cgaacagtag attgtagcta tatcacaggt gagatagtaa tgatcgtgcg aaacaataaa
    23401 ctgatttttc catgcgggat atttgttatc agtgagttga atggaactag cagctattgt
    23461 tttattgtta gtcatctagt gtttttaagg tgcttatttt ctgttacaac agtgatgaca
    23521 acaggttaag ctaagttcga tggagcttgg ttttttattg ttacaagaaa gctcatagat
    23581 ggtgattgca ttcttttatc atatgacaat gtttctattt ttgacaaata ttattgtcaa
    23641 aaagtaaatg atctgttaca ctggagttgg actcatgaaa gaaaaaagta atcagtagga
    23701 taacaataac aaagctattt taagcttata ccattgtgtc aatggattgt tgccggaaat
    23761 gactggtgct ttctgttcaa tcaggagaca gcatttatta ggagtgaagc atggcttata
    23821 ggttgagaaa tcggctcaag gagctacgag ctagagatgg cattaatcag acgcagatgg
    23881 cagcattagc aggtgtttcc aggcagacca ttagcctcat tgagcgaaat gaatacacac
    23941 catctattat tattgcaatg aaaattgcta aagtatttaa tgaaccaatt gaacaagtat
    24001 ttagcttagt ggagggcgag agatgaaagc ttttatgacg gaaaaggaca gtacgttggt
    24061 gagaatactt aagtcattac tgcttggatc agggattggc ttagtgttag gtggccttgt
    24121 tggttttggt ttagctaggt ttaacatatt agaaaatggc tttccgatat cagaagaaga
    24181 caccataact ggaataaagt ggggaatgag accccttgtt atcgtgctta tgctgctgag
    24241 catttatgat atttatcaag ttgtcaaaga atatgctaga tatgtcaagc taagcgatga
    24301 tgaaacagag gagctgtacc gttacattaa tcttaagcat gcctatgctt taggatttag
    24361 cgctatggct atggtcttga atatagtcgt tttttctttg ggatataggg tgcctattgc
    24421 taataatgct agctatcttg gtttgacttt tcctatttac gaggctctga tgcttgtggt
    24481 tattagtgtt ctccatgctt atattttgaa ggtttatact cggattcgcg gggtcaagat
    24541 gacgcttgct cctaccttaa aggaattaaa gcagaatatc ttacaacagg acgaggcaga
    24601 attgcaggct aattatcaaa tgtcttttga ggttgtcatg ggccttagtg gctttatatt
    24661 accaggcatt tacgtaatat tattgctttt atctatgatt tttcaaaggg ttgagctgac
    24721 cggactaatc attactgcta gtattcacct ctatattctg gtgaaatcct ttaaatcagc
    24781 acatgatttt tataggtaag gcgtaaggtt ttacctactc aagaattgtt atacagcaaa
    24841 aaagctttga taagccatta ctggcgatca aagctttttg tgtttgttga aaaagaggct
    24901 tttttgaaag agctgttggc tgagatagct tgtcaaacct acaattgcaa gcggcacaag
    24961 gctaatgaga ggttgtccgg taatttcaat gagaaaaaga ggagcagtaa gaggtatctg
    25021 attaatgatt cccaaaaaga gggtcgctcc aatgacaatg gccaagggaa gtggtacaga
    25081 gagataacct agctgattgc taaggcttgc cagtagcaag ccactagctc ctccaagcat
    25141 catagaagga gcaattttgc ctcctttagc tccagaggca aatactgcat agacagcagc
    25201 tgctttactt agtaagagcg aggcggtata agataggctg acatcatggt gtagcagcag
    25261 gaggagaccg gccttgccat tgcctaaaat ctctgggaaa taaaggctta aacaagcact
    25321 aaagccaaaa gcccctaaga cacgagggat aaaccatcgg ctcttaggct ttgcctttgg
    25381 tgcgttttgg agcagctgct ggtagcaaaa ggccagaaat gctaagatgg gactggcaat
    25441 gatagcccaa aggactgttg tcagttgcca ggcttgtggg agaatgagat actgtatgtc
    25501 ctgatgtccg cttagaacaa gcacactttg aacagcagta aaggcagtta tagctgccgc
    25561 gtaaatgtgt ttaactgagc attttttgac aatagcctcc atgataaaga caatcgtagc
    25621 taatggtgcc tggtaaacag ctccaagggc agctcctgaa gcacaggcta aaagcaatcc
    25681 ttgctctgct gctgatgcgt ttatagcttt attgcaagcg gcagtcagtg ccacagcaac
    25741 ctcacgtgaa gcaccttcac gaccgacagg tgctcccatg gagacggtta ttaattgcag
    25801 ccagccatga caaaattgtg tccaagggct gaaatccttt tgctgactga gtgtttgttg
    25861 gataggctga ataggcttgg cttttttagc aagtagctgc cagccgagac cagcaatagc
    25921 tccagccaac aatagagata aaaaacgcct ttctggagct accgttgcaa tcatggtgct
    25981 aaaagaccca gattggtatc caaagctaat agcctgtatg aaatgaatgg cttgagtgag
    26041 cacgtaagcc accacaccag caatcacacc agctaccacc agttggcccg tccatgttaa
    26101 gaaagtaatc aatcgagtaa tcatatcttt tattatagca gataaaaaga gcctgagact
    26161 actcaggctc caaaatatag ataaatccaa tcttcatgag aagctggact tatagcccat
    26221 aattgtaatc gtcatcagtc atagcttcaa cagtaccaag aaggtagcca ttaccaactt
    26281 gagagaagaa atcgtggttt gacgtgccgg ttgaaatacc attcataacg attgggttga
    26341 catcattggc agtgtctgga aaaagagggt cctgaccaag gttcatcaaa gccttgttag
    26401 cgttgtagcg taggaaggtc atcacttcct cggtccagcc aacctcatca tagagggtct
    26461 tggtgtattg ctcttcattt tcatatagct gatacagcag gtcatacatc cagtcacgaa
    26521 ggctttcttg ctcactctct gatagctcat taaagcccag ctgaaacttg tagccgatat
    26581 aagtgccatg aacggactca tcacgaatga tgagcttaat aatttcagcg acattagcca
    26641 gcttattgtt gcccagataa tagagtggtg taaaaaagcc agaataaaat agaaaggttt
    26701 cgagataagt cgaggctacc tttttttgaa gggcactgcc attttcataa atgtcgttga
    26761 ttatcttagc cttattttga agaaatacgt tgttgttggt ccactcaaaa atgtcttcaa
    26821 tttctttttt ggtgtttagg gtcgaaaaga ttgatgagta ggatttagca tggacagact
    26881 ccataaattg gatattgtta agaactgcct cttcatgcgg ggtgcgcacg tccttgcgaa
    26941 tggcttcgac tcctgactca gactgcatcg tatcaagaag ggttagcccg ccaaagacct
    27001 tacctactaa atccttttca acagcagata atctgcgcca gtcatcaagg tcatttgata
    27061 gtggaatacg tgtatcaagc cagaattgct ccgtcagctt ttcccaggtt gacttgtcaa
    27121 tgacatcttc gatttcattc cagttgattg cttcatagta tgtggtcatg agtttctccg
    27181 gtagattgta atatagggtt aggtatgcta ggaggagagc cttgagtgct ggtctatcat
    27241 taggacaggt gcactgacac atcagctagg ctctgacatt aaggactggt ccacctcact
    27301 gccattcact tggttagatg acacagcttt cacactgatt ggctccgacc tcctcgccat
    27361 catcggtaaa ggtgcggata taatagattg attttatccc tttattaaag gcgtaatgtc
    27421 tcaaaataga taggtcacga gtggtttgct tgctttctgt tttccattcg tagagctcct
    27481 ttggcaattc gctgcgcaaa aagagtgtta acgacagtcc ctgatcaaca tgctttgtag
    27541 cagctgcata gacatcaatc acctttctca tgtccatatc ataggcagat gtgtagtaag
    27601 gaatggtgtc tgtagatagg ccgttggctg ggtaataaat cttgccgatt ttcttttcct
    27661 gacgttcttc gatccgctga gtaatcgggt gaatagaagc agagcagtcg ttgatatagg
    27721 aaattgatcc attaggagca actgccagac ggttttggtg ataaaggcca tctgtcataa
    27781 tcgcttgacg cagcgccttc cagtctgctg cttgcggaat aaagtgatcc ttgaaaaggc
    27841 ttttaaccag ctctgatttt ggcacacatt ctcctgtgat gtactggtca aaataagcac
    27901 cgctagcata tgttgatttt tcaaagccaa caaaggttgt ctgacgctcg cgagcgatct
    27961 gattggattc gacaagcgtc cagtaattca tcagcataaa gtaaatatca gtaaattcga
    28021 tagattctgg gctgccatat tcgatatggt gctgagccaa ataggaatga agccccatag
    28081 ccccaaggcc aaaggtatgt gcttgactgt taccattttt aacagttggg actgcttcga
    28141 tattagagga gtcagtgaca aaggtcaggg cacgtgtcat ggctctgatg gaacgaccaa
    28201 agtcaggtga cgtcatcatg tttaagatat tagttgatcc cagattgcag gaaatatcag
    28261 ttcccatttt gacaaactcc tgcgcatcat taatgagact aggcgtttga acctgtagaa
    28321 tttctgagca taggttgctc atgatgattt taccgtcaat agggtttgac ctgttggcag
    28381 tgtcgatgtt gataacatag ggatagccag attcctgctg gagcttggaa atctctgtct
    28441 ccaaatcacg tgctttgatt tttgttttgg tgatattagg attggcaacc aattcgtcat
    28501 acatgctagt aatatcaatg tagttaaatg gcaggccgta ttctctttca acactataag
    28561 ggctaaagag atacatgtca gcattgtgac gagcaagctc ataaaactta tctggtacag
    28621 taataccaag tgacaatgtc ttgacccgca ccttttcatc tgcattttct tttttggtag
    28681 acaaaaaagc gataatatca gggtgaaaga cgcttaaata caccacacca gccccttgac
    28741 gctgccctag ctggttggaa taagaaaagc tgtcctcaaa tagcttcatt acaggcacaa
    28801 caccagaagc agctccggca tagcccttga ttggagcgcc agcctcacga aggttggata
    28861 ggctaatgcc aacaccaccc ccaatacggg ataattgcaa ggcagaatta atagagcggc
    28921 caatggcatt catatcatct gtcacctgaa ggagaaagca agaaaccagc tcaccacgac
    28981 ggctccgtcc agcatttaaa aaagaaggag tagcaggttg gtaacgctga ttaatcatct
    29041 caatggctaa gtccttagct aatgtttcat caccatcagc aaaataaagg gcattgaaca
    29101 tgacccgatc ctctatgctc tctaagtaga aattgccatc attggttttt agggcatact
    29161 gctgataaaa tttataggcc gccataaatg atttaaagcg aaagccctct gcttgaatgc
    29221 tcttggctag atggctgata aattcaggag aatagttttg gataaaggct gattcaatat
    29281 agtcattgtc tacaagatag gcaatctttt cgttgataga agaaaatgac atggtgttag
    29341 gaataacatt ttcggtaaaa aaagcctcca aagcttcctt gtctttatga agtggaatgc
    29401 tgccatcaac aggacggtta atttcattgt tgaggcgaaa gtaagaaata tcgccaagat
    29461 ctttgagact catatcaatt gttccttgtc tagttaaata atatctttta attttgctgg
    29521 ctgaaaccct gagaatacta tctgctctgt ctcaataaca ggagcagcag taaagccaag
    29581 gctcttaaca tagtccactt tttctggatg ctcatcaata ttaatctctt ggaaagcagc
    29641 tccatgctgt tctaaaaatt tcttagtcat tttgcactgc atgcaattgt gctttgagta
    29701 tactgtaatc attgctcgtc cttccaacta ttagtctttc actcaatttt aggaaaaatc
    29761 aaatgactct aataggatat aaaaaatgtt cctaaaaagc aaacgattta tttcagaata
    29821 gcacaagata ttgtggttgt gtgtgagaat atttctaaat attgtgttat cctctcttat
    29881 cactgataat tgctacaaga ggcttgtagt tcttaaatgc atactaatca ggttggaagg
    29941 cttatttgac attatgaaaa tcatcatgta agaaatattg acaacaaatg aaaatacaag
    30001 aaaactgttt catgattttt tcttgttaga acatttaacc ttgaaaataa aaaagcattg
    30061 tgctataatc acttattgta agggttatca tgtgatagct cgaaaataca caattcaaaa
    30121 ggagaaccat attatggctt caaaagactt tcacattgtt gcagaaacag gtattcatgc
    30181 acgcccagct accttactta ttcaaacagc aagcaaattt gcttcagata ttacacttga
    30241 ctacaaaggt aaagcagtaa atcttaaatc aatcatgggt gttatgagcc ttggtgttgg
    30301 tcaaggtgct gacgtaacaa tcacagcaga aggcgctgat gcagatgacg ctattgcggc
    30361 aatcgaagaa actatgacta aagaaggatt ggcataagac tatgacagaa atgcttaaag
    30421 gaatcgcagc ctctgacggt gttgctgttg ccaaagcata tctgctagtt cagccggatt
    30481 tgtcatttga gactatcaca gtcgaggata caaatgcaga agaagctcgc cttgatgttg
    30541 cactacaagc ttcacaagac gagctttctg ttatccgaga aaaagcagta gaaagcctag
    30601 gcgaagaagc ggcagcagtt tttgatgccc atttaatggt tcttgctgat ccagagatga
    30661 tcagccaaat taaagagact attcgtgcga agcaaacgaa tgctgaaaca ggtctaaaag
    30721 aagtgactga catgttcatc acaatctttg aaggcatgga agacaatcct tatatgcaag
    30781 agcgtgcggc tgatattcga gatgtcgcta agcgcgtctt ggctcattta ttaggtgtta
    30841 agcttccaaa tccagctaca attgatgaag aagcaattgt tattgcacat gatttgactc
    30901 cttcagatac tgcacagctt aacaaacaat ttgtaaaagc atttgtaacg aacattggcg
    30961 gacgtacgag tcattcggct atcatggccc gtacacttga gattgcggct gtgcttggta
    31021 caaatgatat tactaagcgt gtcaaagatg gtgaccttat tgctgttaat ggtatcactg
    31081 gtgaggttat tattgaccca agtgaggagc agattcttgc tttcaaggaa gctggagagg
    31141 cttatgcgaa gcaaaaggct gagtgggctc tgcttaagga cgcacaaact gtcacagcag
    31201 atggcaagta ctttgaatta gcagcaaaca tcggtacacc taaggacgtt gaaggtgtca
    31261 acgataatgg tgctgaggcg gtaggtcttt accgtactga gtttctttat atggattctc
    31321 aggatttccc aaccgaagat gagcaatatg aagcctacaa ggctgttctt gaaggaatga
    31381 acggcaagcc tgttgttgtt cgtacaatgg atatcggtgg ggacaaggag cttccttact
    31441 ttgatttacc aaaggaaatg aacccattcc ttggttttcg tgccttacgc atttcaatct
    31501 ctgaaacagg taatgctatg ttccgcacac aaattcgtgc tttgctgcgt gcttctgtgc
    31561 atggtcaatt gcgtatcatg ttcccgatgg ttgcccttct aaaggaattt cgtgctgcta
    31621 aagtcgtatt tgaagaagaa aaggctagct tgctgtctga gggtgttgcg gttgcagacg
    31681 atattcaggt tggtatcatg attgagatcc cagcagcagc aatgcttgct gaccaatttg
    31741 ccaaggaggt tgacttcttc tcaattggta caaatgacct tatccagtac acaatggcag
    31801 cagaccgcat gaacgagcaa gtgtcatacc tttaccagcc atataaccca tcaatccttc
    31861 gtttgattaa caatgttatc aaagcagctc atgctgaagg taagtgggct ggtatgtgtg
    31921 gtgaaatggc aggtgaccaa caggctgtgc cgcttcttgt tggtatgggg cttgatgaat
    31981 tttcaatgtc agcaacatct gtgcttcgca cacgtagcct gatgaaaaag cttgattcag
    32041 cgaaaatggc agagtatgct catcgtgcac tcacagaatg ctcaactgct gaagaggttc
    32101 ttgagcttgc caaagagtat attacagaag cttaaataga aataacgagg agctggtttt
    32161 gtccggctct tttttactag aaaaatgact aatcagatcc atatgaaagc ttgctttata
    32221 aagtagtttg atgtttcaag ttttatcaga attttcagac tcttcctgta gcgaattgtt
    32281 gaaatatgct aaaaaagtga tagaataata gtaccattat aaaaggagaa aaaagtttgg
    32341 ctaaacaata taaaaattta gtgaatggtg agtggaagct ctctgaaaat gagatcaaga
    32401 tctatgcacc agcaaccggc gaggagttag gtagtgtacc agctatgtct cgtgaagagg
    32461 ttgatcaggt ttatgcgtca gctcgcgctg ctcttgcaga ttggagagcg ctttcttatg
    32521 ttgagcgtac tgcttatttg cacaaggctg ctgatatttt ggtgcgtgat gctgagaaga
    32581 ttggtgctgt tctctcaaaa gaggttgcaa agggttataa ggctgctgtt agtgaggtta
    32641 ttcgtacagc agaaattatt aactatgcag cagaagaagg ccttcgtatg gaaggcgagg
    32701 tccttgaggg tggcagcttt gaggctgcta gtaagaaaaa gattgcgatc gtacgtcgtg
    32761 agccagtggg acttgtgctt gcgatttcac ccttcaatta tccgattaac ctagcaggct
    32821 caaagattgc tccagccctt attgcaggaa atgtcgtggt tcttaagccg ccgacacaag
    32881 gctctatttc tggcttgctc ttagcagagg tatttgcaga agcaggtctt cctgctggag
    32941 tctttaatac catcactgga cgcggctcag ttattggtga ttacatcgtt gagcatgagg
    33001 ctgtaaactt tatcaacttt actggctcaa cgccaattgg agagcgaatt ggtaaattag
    33061 ccggcatgcg tccgattatg cttgagcttg gtggtaagga ttcagcgatt gtcttagaag
    33121 atgctgatat tgccttagct gctaaaaaca ttgttgcagg tgcctttggc tactcaggtc
    33181 aacgctgtac agcagttaag cgtgtgcttg ttatggaaag cgttgcagac cagctggtag
    33241 cagagattaa gggcttagtt gagaaattac ttatcggtat gccagaggac aatgctgaca
    33301 tcacaccatt gattgatacc aaagcggcag attttgttga aggtctggtt aatgatgcag
    33361 cagacaaggg agcacaggcg cttactgaaa tcaagcgtga cggtaattta atttgtccta
    33421 tcttgtttga tagagtaaca actgatatgc gcttggcttg ggaggagcca tttggtccgg
    33481 tgctgccagt gattcgtgta agctctgtag aagaggcaat cagcatttca aatcaatctg
    33541 aatacggttt gcaagcgtct atctttacga ctaattttcc acaggccttt gctattgctg
    33601 agaagcttga ggttggtaca gtacacatta acaacaaaac ccaacgtggt acagataatt
    33661 tcccattcct aggggctaag aaatcaggag ctggtgttca aggggtcaaa tattcaattg
    33721 aggcaatgac aagtctcaaa tcagtcgtat ttgatattca ataacaaaaa agctagggta
    33781 tcttagtttg aaagcagttg cacatttgtg cggctgtttt atttgtgtct ctagttttaa
    33841 cagctagcta tgcaagaagg tgagttgtcc caacctcaaa gatgagatct aaatatttaa
    33901 tgattttggg gtcgtaaaaa agtttagagt gttttgatct ccttaagatg tgagtgtaca
    33961 aagtctcgcc aacagccagc aggactagcc attgaggtca aggaagctgc taaaatagct
    34021 gatggttcaa aagcttggtg aaaggcttaa tatctatcat tgctattttg agggctttcc
    34081 attataatat gaatactaga gctacttgtc ggtctgcctc ttgagctgtg agatagctgt
    34141 tggatttagt tgtctccttg tccacaaaag gcttagaggc aaaggctgtg gctatgcttc
    34201 ttgcttcttt tagtgaagtg tatgagatct tatgaaaact catataggct ttggtatctt
    34261 tgcaagagga ctaatggctt gctttacttg ccttgataga gggctgggat tgaggggtga
    34321 tgacctgcgg tggtcatctc tagagctcct tgcttctttt tttatgtaga ctaatggttt
    34381 agactgctag cttccttgtt tagaaagtag gacatcatgt tacccaagag aaaattaatt
    34441 gatcaacgtc ttgattatgc cattattttt cctgtttttt gtttgctaat atttggtctg
    34501 gtatctgtat atgtggcagc aagtcatgat tttccgcaaa gcctcgccac tgttatgctt
    34561 caacaggttc tctggatcct tcttggagct gtgattgcct ttaccctaat gttttttagc
    34621 acagagattc tgtggaaatt aacacctgtc ttttatcttt tgggtgtgct attaatggtt
    34681 ctgccactca tcttttttag ccctcggctg gtagctgcta caggggcgaa aaattggatt
    34741 acgattggct caacgacctt gtttcaacca tcagaattta tgaaaatatc ctacattctg
    34801 gcaatgtctt ggttaacggt ctggtttaag agaaagcagg agagaagtcg gtttttagat
    34861 gattggaagc tcttgggctt ataccttgtc ttgacgttgc cggtcatggt cctgctagca
    34921 ctgcaaaagg acttaggaac agctatggtt tttttagcca tcttagctgg gattatctta
    34981 atttcaggaa tttcttggtg gcttatttta ccagctttgg tactagtctt tttactggtt
    35041 tcagcttttt tctttgtttt tttgttgcca gagggaaaag aattcctttt aaaaatggga
    35101 atggatacct accaattgaa tcgtatttca gcttggctga caccgtttga tttctcagat
    35161 accattgcct atcagcagac gcaaagtatg atttcgattg ggagtggtgg cttttttggt
    35221 aagggcttta atcagcttga gctgtcagta ccagtcagag aaagtgatat gatttttaca
    35281 gtgatcgctg aaaattttgg ctttcttggt gcagctagct tactgatctt gtatttaata
    35341 ctgatttacc gcatgcttag ggtgaccttt gcatcgaata acctttttta tacctacatt
    35401 tcaaccggct ttatcatgat gatactattt catatttttg aaaacattgg cgcagcagtt
    35461 ggtctgctac ctttgaccgg tattcccctt ccctttattt ctcagggcgg ctcttccttg
    35521 atttcaaatc tgattggggt cggcctgatc ctatcaatga actatcagca cgtccttgct
    35581 catgaaaagc aaagcgagca tgagcttagc agaagctcac gttatgttta agaggcatgt
    35641 ttggtccttg ttcggttaga atgagctgcc aatcagccct tttttatttg cttaatcgct
    35701 ataaaaataa agaaaaatat gttataatta aggttatgaa ttatcatgat tatatttggg
    35761 atttgggcgg cactctcttg gataactatg aaatttctac ccaggctttt attgagacgc
    35821 tgcatttttt taagctgtct gcaagccacg atgccgttta tcaaaggctt aagaaatcaa
    35881 cagcaaccgc cattcaagta tttgctccca acgaaccgca atttttacaa tattacaaag
    35941 cgaatgaggc taagaaatta gccaatccta tttggtgcct aggtgcaaag gacattctaa
    36001 agaggattgt ggcatcaggc tcgcgtaatt ttttaatatc ccatcgtgat catcaggtca
    36061 atgatttgct ggagcaggct gggcttttgg gctattttac cgaggttgtt accgcctcaa
    36121 atggctttgc cagaaagcct aaccctgaga gcttacttta tttgaaggaa aagtacctga
    36181 tcagcaaggg cttagtgatt ggtgatcgca gacttgatat agaagcagga caagcagcag
    36241 gctttgacac cctgcttgtt gatggtagaa aaaacctatt ggagatagta gattagatgg
    36301 ttgaagaaaa taaacaatta gaagacaagg ctcaagagta tgacgctagc cagattcagg
    36361 tcttagaggg gttagaagcc gttcgcatgc gtcctggaat gtatattggc tcaactgcca
    36421 aggaaggctt acatcaccta gtttgggaga ttgttgataa ttctatcgat gaagccttgg
    36481 caggctttgc cagtcatatt caggttttta ttgaggcaga taattcgatt accgttattg
    36541 atgatggacg tggtatccca gttgatattc aagctaagac aggccggcct gctgtagaga
    36601 cagtttttac agttttgcat gccggtggaa aatttggcgg tggtggctac aaggtttctg
    36661 gaggacttca tggtgttggc tcctcggttg ttaatgcctt atccacacag cttgatgttc
    36721 gtgtctataa aaatgggcat atccactatc aggagtttag gcgtggtgct gtagttgatg
    36781 atttggctat cattggaacg actgatgtta cgggaacaac agtgcatttc acacctgatc
    36841 cagagatctt tacagaaaca acagaatttg actaccaggt cctggcaaag cgtattcaag
    36901 agctggcctt tcttaatcgt ggcttaaaaa tctcaattac agataaacga gctggtcttg
    36961 aaagagaaga gcatttccat tacgagggtg gtattggctc ttatgttgcc tttttaaatg
    37021 acaaaaagga cgtcatcttc gatactccga tttattctga tggtgagctg gaggggataa
    37081 cagttgaggt ggcgatgcag tacactacag gttaccatga gactgttatg agctttgcca
    37141 acaatattca cacacatgag ggtggtaccc atgagcaggg ctttagaaca gctctgacgc
    37201 gcgtgattaa tgactatgct aagaaggcta agattctcaa ggaaaacgag gataatctga
    37261 caggtgagga cgtccgcgag ggcttgactg ctgttatttc tgtcaagcac ccaaatccac
    37321 aatttgaagg gcaaacaaag acaaagttag gaaattctga ggttgttaag attaccaatc
    37381 gcttgtttag cgaagctctt cagcgctttc tactagagaa tccgcaggtt gcccgtaaga
    37441 ttgttgaaaa ggggattcta gcctctaagg ctcgcattgc tgccaagaga gcgcgtgaag
    37501 taacccgcaa aaaatcaggc ctagagattt ccaatttgcc agggaagctg gctgactgct
    37561 cctcaaatga tgctagtcaa aatgagcttt ttatcgtgga gggggattcg gctggtggat
    37621 cagcgaagtc aggtcgcaat cgtgagtttc aggctattct gcctattcgt ggtaaaattt
    37681 taaacgttga aaaagcaacg atggataaaa tccttgctaa cgaagaaatc agaagcctct
    37741 ttactgctat ggggacaggc tttggagcgg agtttgatgt ttctagagct cgctatcaaa
    37801 agctggtcat catgactgat gcagatgtcg atggagctca tatcagaacg cttttgttaa
    37861 cgttgattta tcgcttcatg cgaccagtat tagaggctgg ctatgtttac attgctcagc
    37921 caccgattta tggtgttaag gttggcagcg agattaagga atacattcaa ccgggagtca
    37981 accaagaaga ggagctaaag gctgctcttg aaagacatag cacaggacgc tcaaggccga
    38041 ctattcaacg ctataagggc ctaggagaga tggacgatca ccagctttgg gaaacaacaa
    38101 tggaccctga taatcgtcta atggcacgtg tgaccgtaga tgatgcggca gaggctgatc
    38161 ggatttttga catgctgatg ggcgatcgtg ttgagccaag gcgtgaattt attgaggaaa
    38221 atgcggtcta tagtacgctt gacatttagt caaatatatt ttgaaaagca cctaaaagta
    38281 tgttataatc gtaacgttat agtgtatttt tgataatata ataaaaggcg attcttgcta
    38341 gttgttccta ctgaaccggc agttgatcaa tcgcatctaa ataataagga gattaagatg
    38401 tcaagcggaa ttatcttgct gattgtggcc atagtcttac tagtgattat tgcttattta
    38461 gtgggtgtta ttatacgcaa gcgtaatgac acattaatta ccagtctaga agaacgaaaa
    38521 caagctttat ttggccttcc tgttaatgac gaaatcgagg aagtcaagtc tcttcacttg
    38581 attggtcaaa gccagacctc atttcgtgaa tggaatcaaa agtgggttga tttgacccta
    38641 aataccttta ccgatattga aaagcatatc tttgaggctg agcacttaaa tgacaccttt
    38701 aatttcattc gtgccaagca tgagattaat agcgttgaga gtcaattgaa tctcgttgaa
    38761 gaggatatta ccgctattcg tgaagcactt ggcatattaa aggagcagga agaaaaaaac
    38821 agcgcgcgtg ttactcatgc actagatttg tacgaaaagt tgcaggcttc cgttgctgaa
    38881 aatgaagata atttcggatc aacaatggcc gaaattgaaa agcaaatgaa gaatattgaa
    38941 gcagagtttt cacaatttgt tgcccttaat tcatcaggtg accctgttga agcagcggag
    39001 gttttggata aggctgagga gcatacgatt gccttggggc aaattacaga gcagatccct
    39061 gctattgtag caaagcttga agatgatttt ccggatcaat tggacgatct ggagacaggc
    39121 tatcgtcgtt tgctggagga aaattatcac ttcccagaaa aaaatattga agcccgcttt
    39181 caagagattc gtgagtctat tcgtgccaat tcatcagagc tggttaccct tgatttggac
    39241 cgagctagag atgaaaatac tcacattcaa gagcgtatcg actcactgta tgagctcttt
    39301 gagcgtgaga ttgcagccta caaggtggtt gctaaaaata gcaaaatatt accaagatac
    39361 ctggctcacg ccaagcacaa caacgagcag ttgaagcatg agattgctcg tctatcacgt
    39421 aagtatatct tgagtgaaaa tgaaggctta aatatcaagg cctttgacaa agacctcaaa
    39481 gatatcgaag acaatgtcct tgagattgct gaagcctttg atcagcagga aaagccattt
    39541 tcagagctac agctgattct tgatcgtagt atcaagacgt tggcttctgt agagtctggt
    39601 cagatggacg tctttgctgc tgttaaagac attgaaaaga ttgagtcaca ggctcgccag
    39661 cacttagaaa tctacgtcac acagcttcac atgattaagc gttatatgga aaagcgcaat
    39721 ttaccgggaa ttccacagga ttttctgagt accttcttta ccactagttc gcagctagaa
    39781 gcattgatgg acgaactaag tagaggacgt atcaacattg aagcggtgtc ccgtctgtct
    39841 gaggtggcaa cagctgctat tgctaatcta gaagagctaa cctaccaagt ggttcagcat
    39901 gctaccttga cagagcagct gctccagtac tctaaccgtt atcgttcctt tgaagctggc
    39961 gtgcaaaata gctttgagca tgccttgaaa ttgttcgagg tggacaatga ctatcaggca
    40021 tcatttgatg agatttccta tgccttggag acagtcgagc caggagtgac agagcgtttt
    40081 gtcaattcct atgagaagac acgtgaacgt atccgcttct aatgtgacaa gggttgatac
    40141 tttatattac gaaaaagctt gaaaaagcag tccatgctgg gctatgcttt ttcaagcttt
    40201 ttgaatggtc aggctatggc ctccttgagc tatacccaaa aagctggttc aagccagtca
    40261 gtagagatag acaaggcctt agtgctattg ggctgttgct acatgagata ttttgtaata
    40321 aaatcagacg attatccatt taattaaaaa aaaaaaaaac gaaactgcgg aggaaacctg
    40381 acgagtaact atttatggct atcaatcagc atgttacact ctttttggaa ggcctagcaa
    40441 tcactgactg tgaggttaac caaagaaaat aagatgttaa ggagaatatc aatgaaaata
    40501 actaaagcat tgtgtgtagc aggtgctgtt gcagtcctag ccttggcacc aatcagctca
    40561 agtcctgcac caacacagac tgtatttgct gctacacgtg gtactgaaga gtactgtcat
    40621 aatgggtggt gcagttttct tgatgaacat ggtgagtgga acacgaaacg tgagggcgaa
    40681 tctaatagtc ccctacagcg aggttcatgg tgggattgga tttcttattg gtctggttat
    40741 atatggtatt ctgtatataa ctggtttagg taacctctca acgccactgc taccatactg
    40801 ataaatccct tagactattc taagggattt ttactgcaaa aagcacatag ggacaaggca
    40861 atacaagctc cagcctgttc ttagctccct ataccggtaa ggatcataac actcagaact
    40921 ccggcagatg attgcaggag ctattggaga gtgaggacta gtgaaagagc ctctgccaga
    40981 gggatttgcc cttagtcttt gtttgttcag caggcttatt gtcagagggc ttgtctagta
    41041 tagccttgag attggtttcc tctttggtga tggcatgatc actatgaatg atcagagcaa
    41101 aaggagagac agctcctttc tcatctacaa tagtggcaga tagagcgttt tgttgggcca
    41161 atttcatata gtacatttga taagcagagc cgaattcaga ggataatttg aatgacaagg
    41221 ggaaataagc ctctttgagg tgaggcagct gggctgtgat gtagccttta gccttttcat
    41281 gatcaacctc tgtcaaggga agcgctaaga caatcctttc agcataggtc cctaaataat
    41341 agcgttgttg gtcggggtca aatcggtttt ctcctgaagc tccctttaag agtcttgtat
    41401 ctaatgaatc catacaatcc tttcaagcat gtgatactgt cattatacta ttaactgcgc
    41461 caaataccaa tgataaagca tttactaggt atttgatcgg cttttggaag aagatgaaat
    41521 caaagaaaaa cagcatgaaa acaactctct tatttcatga aattagtttt taagttgctt
    41581 aagaccctag tttgtggtat tattaacatg taaaatatta aaactcataa ggagagtatt
    41641 ataatgtcaa ttattactga tgtttacgct cgcgaagtcc ttgactcacg cggtaaccca
    41701 acacttgaag tggaagttta tactgaatca ggtgctttcg gacgtggtat ggttccttca
    41761 ggagcttcta ctggtgagca tgaagcagta gaacttcgtg atggcgacaa atctcgttac
    41821 cttggtcttg gtactcaaaa ggcagttgac aacgttaaca acattatcgc tgaagcgatc
    41881 attggttatg atgttcgcga tcaacaagct attgacagag ccatgatcgc tcttgacggt
    41941 actccaaaca aaggtaagct tggtgctaat gctattcttg gtgtgtctat cgctgtagcg
    42001 cgtgctgctg ctgactacct tgaggtgcca ctttacactt accttggagg attcaatact
    42061 aaggttcttc caactcctat gatgaatatt atcaacggtg gttctcactc agacgctcca
    42121 attgctttcc aagagttcat gattatgcca gttggtgcac ctaccttcaa agaaggtctt
    42181 cgttggggtg ctgaggtatt ccatgctctt aagaaaatcc ttaaagcgcg tggacttgtt
    42241 actgctgttg gtgacgaagg tggatttgct cctaaatttg aaggaactga agatggtgta
    42301 gaaacaatcc ttaaggctat cgaagctgct ggctatgaag ctggtgaaaa tggtatcatg
    42361 attggttttg actgtgcgtc atcagaattc tacgataaag agcgcaaagt ctacgactac
    42421 actaagtttg aaggtgaagg cgctgctgtt cgtacatctg cagagcaaat tgactacctt
    42481 gaagaattgg ttaacaaata cccaattatc acaatcgaag acggtatgga cgaaaatgac
    42541 tgggaaggct ggaaagcact tactgagcgc ctaggcaaac gtgttcaatt ggttggtgat
    42601 gacttcttcg ttacaaacac tgaatacctt gctcgtggta tcaaagaagg tgcagctaac
    42661 tcaatcctta tcaaggttaa ccaaatcggt actttgactg aaacctttga agctatcgaa
    42721 atggctaagg aagctggcta cactgctgtt gtatcacacc gctcaggtga aactgaagat
    42781 tcaacaatcg ctgacatcgc agtggcaaca aacgctggcc aaatcaaaac aggttcattg
    42841 tcacgtactg accgtatcgc taaatacaac caattgcttc gcatcgaaga tcaacttggt
    42901 gaagttgcac aatacaaagg gatcaaatca ttctacaacc ttaaaaaata atttgatttt
    42961 agattaaaag gttgacaagc cttgatttta aagcattcta ggactgtcct agagtgcttt
    43021 tagttttagc ttcatgtcaa ctgtagtggg tgactgatag ctaagcacga gaggagacga
    43081 aggtcgcctt ctctttttca atcggataag gctagggaat ccccaaatgt cgatgaaggg
    43141 aattttagaa ggtttctgga agtcgtatat gatttgtttc cctttgcagt gtctacacct
    43201 aggagactga tagtccagtg tagcgctgac ttcgatatga gtatcgtgct ggatagtctt
    43261 attcaaggtg atattttgat ctttgattcc gatgagtagt gtggtatgat gaatctgttc
    43321 cataagacac tttctaatga tggtctggtc gcttttcatg ataagcctta tggaactttt
    43381 tgggtactca aaaagcccta taatcttcat aatgaattta cccattacag aaattataga
    43441 gccaatattt agaggatttt agcctattgg tagattgaca gtttcttaag attgtgttac
    43501 aatgtaacac aaagaaacga ggtaaacgac tatgagtaca gttactatca gattaaatca
    43561 agaagaagaa atatttttca aaagttacgc ccaactcaca gggcaaagtt tatcaagtct
    43621 atttaaaaaa gcccttgagc gggatattga agatgagtat gatttaaaaa tctatcatca
    43681 agcctatgct gaatataaag cagaccctga gacaattagc catgctgatt ttaagaaaga
    43741 gctaggctta taacatgtac cgtatagagt attctaaaaa ggctcaaaag cagattaaga
    43801 aagtagataa gcaaattcag aggttgctat ttgcttggat tgataagtat ttagagggaa
    43861 cagataaccc acgcgcaaat ggcaaaggtt tgaccggaaa tcatgctaat gagtggcgtt
    43921 atcgtattgg tgattatagg cttatttgtg atattcaaga tgataagatg gttgttttag
    43981 cgcttgagtt tgggcatcgt aaagatattt actaacgttg aggaagtaag atggtcaaaa
    44041 ataatgcaat tggtagcaac tggaaagatg taagagctga gttattcagc aaggaagaat
    44101 tttagaaagt gatgctcgta ttgctattat ggacaagtat agttaaaaag tgtgcgtttt
    44161 taatctgtat gatgaagtaa ttgataaagt aacaggtcaa aaggctatca ttgtctgtat
    44221 tgctaataaa ttggtagatg attgttattt aatcgaaccg ctaaaccatt cttacttacc
    44281 agattggcgt gagataaatc agttaattcg atataaaaat tagcacctta tcgggtgcta
    44341 attccttgcc tgctgaactc ataatttaat acctttttta ctaccccata tgtttcccct
    44401 aattatgtgt acttgctaga tataaggtta attgggatag aattttgaat aaagttgttg
    44461 tattttgtaa tagtgattga tattgggata accttaaaaa aataatttga ttttagatta
    44521 aaaggtttac aagctttgat tttaaagcat tctaggactg tcctagaatg cttttagttt
    44581 tgataagcac aatccgctgt tgactgtata aaccgtatat gatacaaaat aagagcttgt
    44641 agcagtgaag ccactaactc tagtgctgtg ggctcaacct tgattgatga atcccttgct
    44701 tttaatgcgt ttatgaagca gtggcgtatc agtctagctc gttgtggaaa gcaattaact
    44761 agagaagaat tactatcctc aatcaatatg ctgacagccg cagggatttg tgagtttgat
    44821 ttgctgtggc agcgtcttgc tcctaagggg tgtcagcgtc ccaaatggag ccatcagctg
    44881 gagaggctct ttgcggatac aaagccttgt ctacaggtct tgtctgagac ttatcagctt
    44941 gggattattg ctaatcaggc aaagggtcta aaagagcgct tagagaggtt tgggattagt
    45001 cattattttg cccttatgat atcttcttct gatgtggggc tacaaaagcc tgatcttgct
    45061 ctgtttcgct atgcacttga tcaagcaggc gtattagcgc gtgatgctgt ttatattggg
    45121 gatcgtgttg acaatgatat tattcctgct aaggcattgg gaatgagagc tgtcaggatt
    45181 catcaagggc ttgctgcgtc cagtccagat gataggcttt atcctagtga tgtccatatt
    45241 agcaaactta gtgacctgtt agaatgcttt taaccagtct ttagcttgaa ctagcttttc
    45301 tttgtggtct ttctgggtga atggcagcaa gctttggagt catgttatgg ctagaccttg
    45361 gatctaaggg cgctgagcgt ctcatatgat gaggccgatc aagtagtctc cttgacaagt
    45421 agattattgt ttggtgctta taggtggctt taggtgatga ctggttttgc ctcaactaag
    45481 gctcgctatt gctatctggg gtatcttctg acttttttaa tgtgctctta tctggttgga
    45541 ttagacctgc tccttgcttg aggaaagctg tttttaacgc tgatgagtct gggaaatggt
    45601 gagattggtg ttggctttta ctagtttttt tgcgtttact tgggctaact ttatatgaga
    45661 aaaaaagaaa aatatttatt ttatctgtta tttttgttac aataagcgtg taaactaaga
    45721 tgcattaaaa aggagttttt atgtcgaata agaaattttt tacttatgct tcattattgg
    45781 cattaatcgc tgttcctact gtggttgaag aggtgactgc acagccttca gctcagcttg
    45841 tttatgcaga tgagctaagg ctatcaccaa gtaccgactc atctccagta acaaagaccg
    45901 atgaggctga tcagccagtt gctcaatctg tttctgcgac agaaccagta gaggctcttg
    45961 ttattgcgga taaagaaagc gctttaaatc ctgctgttct agctgatgcc gatggaagtc
    46021 agccgattgc agtggttaga gctggtcaag agggtcagcc ttataccgtt actggcaaaa
    46081 tcatcagtgc tgttaatggc tggggtggtc atggctttta tatccaggac agtcagggat
    46141 caggtcttta catttatcca ggaagtgctt tggggtacgt gactggtgat gtggtgcagc
    46201 tgacaggaac actgactact tacaagggtg agcttcagct taaaacgatt acaaagcatc
    46261 ataagattaa tggcgaatta ccaacaccta ttgctgaggt aaccattccg gagctagaaa
    46321 aagcaagccc gtctaccctg gtgaagcttt caaatgtgac tgttggagac atttcatcag
    46381 ataagcacga aacctcctct tttaaggtca gcgatacagc tggcaatagt gttgcggtgc
    46441 gtcttgataa tcgtacaggt gttaagacct ctgacttact ctctaaaatt ggcaagggtg
    46501 atgtgattaa tctgacagct attcactcaa cctttgatgg gaagctccag ctcaagccct
    46561 ttagccttga gcaatttgag gtagtaaaga aggttgttcg agaagaagag gtgactcctc
    46621 ttggtcgagt ggttaaaatc ggccaaattc aaggtgccag ccacacctca ccgctcttga
    46681 atcaagctgt aacagtaaaa gaggtggtgg tgacctatct tgatgatgca actcatttct
    46741 atgtgcaaga tattaatggt gacaacgata aggcgacctc agacggtatt cgtgtctttg
    46801 ctcaaaatgc tcaggtgcag gctggtgatg tgctgaccat ttccggaaca gtggaggagt
    46861 tctttggcaa aggctacgat gaccgtaagc agacggatct gaccattacg caaatcaagg
    46921 catctaaggt cactaaaaca gggactgctc aggtaccagc tccgcttgtg ctaggtaagg
    46981 atcgtgttgc tccagctaat atcattgata atgatggctt tagtgttttt gatccagaag
    47041 aggacgctat tgatttttgg gaatccttgg agggaatgct tgttgccgtt gataatgcca
    47101 agattttagg gccgatgtct cataaggaaa tttatgtgtt accagggtca tcaactcgag
    47161 tgctgactaa ctcaggtggt attttacttc ctgagacagg ctataataca gacctgattc
    47221 ctgttctctt taaaaaagga aagcaaacca tcaaagctgg tgattcctat cagggacgac
    47281 ttgcaggtcc ggtatcatat agctatggta attataaggt gtttgtcgat gacagcagtc
    47341 gtatgccagt cttggttgat ggtcagctga agcctgaaaa gacacacatc aagaaggacc
    47401 ttagcaagct aagcattgcc tcatacaaca ttgaaaactt ctcagcaaac ccatcatcaa
    47461 caaaagacga gaaggtaagg cgcattgcag aatccttcat ctatgaccta aatgctcctg
    47521 atattattgg tctcatcgag gttcaggaca ataatggacc tactgatgat ggcacaacag
    47581 atgcaacaca aagcgctcag cgcttgattg atgccatcaa ggccttaggt ggaccagctt
    47641 atcaatatgt ggatattgct ccggaaaata acgctgatgg tgggcagccg ggcagtaata
    47701 ttcggacagg cttcctgtat cagccaggac gtgtcagcct ttctgataag cctagaggtg
    47761 gtgttaatga tgcggtgaaa tgggtaaatg gtgagctaag cttgagtgtt ggacgtattg
    47821 acccaacaaa tcctgcttgg aatagtgtta gaaaatcatt ggctgctgag tttattttcc
    47881 aaggccacaa ggttgtggtg gttgccaatc atttgaattc caaacgaggc gacaattcat
    47941 tatatggacg tgttcagccg gtaaccttta aatcagagga aagacgtcat gtcttagcaa
    48001 ggcttttgag ccaatttact aaggaaggtg ctagtcagca ggctaatatc gttatgttgg
    48061 gtgactttaa cgattatgag tttacgaaga ccattaagct gattgaagaa ggagatatgg
    48121 caaatttggt gagcaggcat gagctttctg accgttattc ttacttctat agaggaaata
    48181 accaaacgct tgataacatg cttgtttcac gcaatttgct tggtcgctac gagtttgaca
    48241 tggttcatgt gaattcacca tttatggaag cgcatggacg tgcttctgat catgatccgt
    48301 tgcttcttca gctctccttt ggaaaagaca agccagcagc accatcagat cagccaaaga
    48361 aaacaccagc accagctgcg acaactcaag cctctaaggc aggacgtgca cagctattgc
    48421 caaaaacagg tgataagaca gcgcttatgg taagtatttt aggcttaaca gctgtcttta
    48481 gctcctttag cctgtttagg aaatgtcagg aaaggaagta aaggatttct ttggggtagg
    48541 ccagcagctg agcggctact gcgttttgtc tgctggtgct atataggtgg ttgaagcgag
    48601 cgaagagagg tatgcttcct aggatcatag cacaatatct tatgcttata aacgaacaca
    48661 atgctcctta tgagcattca aaacctatac tcaaaaggaa tataacagct gagttaagag
    48721 ggattgcttt tgacagattg tggtaaaaaa agggatcttg aggaattggc tagtgatcta
    48781 gctgccaaaa tgcgatgtct tgtttgacta tttttcccta ttgggatata atgacaatag
    48841 aaaaagggta gttgtttgcg caactaccct gtgcagaacc gtttaagacg gtggcagaat
    48901 gaaagttaaa aaataatcgt cgacctacca aagttcagac ggttattttt tattgtttaa
    48961 tatgacgatt gcaacgacta agctgattaa ggtaagtaag aaactaccaa aagccagcat
    49021 gagttgaagg gcctcgtaag tagacaataa aacgctcctt tcagttggat tttgatgcat
    49081 tgcccatagg catcaccacc tttcagaaat cagagccacc gtcttagctt ttctgtaaag
    49141 aacattatat cataatcaca tgagaaagcc gttagatttt aaactgatca ggcggctttt
    49201 tggtgttttg ctgtctttta gtggaatcgc ctaagctttg ctgtatagta tgggatttta
    49261 tgctttttgt aagggcttag gctgctatgg cagggtccat gtcctttgtc aatagcttag
    49321 ttttatggta caatgtaggc gttgcctagc aacccttggt gcttagttcc ctttcaccaa
    49381 gcatattaca aacgtggcgg agctgtttat gctctagtct gacgtcaaag gagaaacaca
    49441 tgacaagttt tactgttcgt gactatgttt acattgctct agtggctgcc ctttatgtgg
    49501 ttttgacaat cactccacct ttgaatgcta tttcctatgg catgtatcaa tttcgggttg
    49561 ccgagatgat gaattttttg gctttttacc ataaaaagta tatcattgcg gtgaccttgg
    49621 gctgtatgat tgctaatttt tatagctttg gcttgattga tgttttggtg ggtggaggct
    49681 caacgctcat ttttgttagc ttaggtgtcg ctttatttaa gcaataccaa gaggaatatc
    49741 tcttaaatgg cttgctgaat aaggcctttg tttatttctc actatttttt gcgacttcta
    49801 tgatcaccgt tgcgattgag ctttacttct ttggagcacc atttttccta acttggttta
    49861 ccactgctgt aggggaattt gcttcactta tcattggctc tatgatcatt gatcgcttat
    49921 caaaacgcat taatttacga caataatagt aacatgtagc cttccgtttt tgggaggctt
    49981 tttatgattt tcttctagct aggcaatagc ttatttgcta tgttttgtga taaaataaga
    50041 ctatgaaaaa acgcataaga gaattgactg atctgttaaa tcaataccgt caggagtatt
    50101 acaccaatga cgctccttct gtatctgata gtgagtatga taagctttat cgtgagcttg
    50161 tagagctgga gcagacctat ccagcctata tcctaaagga cagccccaca cagctggtgg
    50221 gcagtacgat tttgacagga tttcagaaat atcagcacca gtatccgctc tttagtttgc
    50281 aggatgcttt ttcacgtgaa gagcttaacg cctttgatca gcggatcaaa tcagcctttc
    50341 ctgaggctga ataccttgct gagctaaaaa ttgatggctt gtccatttcg ctggtttatg
    50401 aggctggtgt tctaaaggtt ggagcgacac gtggcgatgg gactattggc gagaatatca
    50461 ctgaaaacat taagaatatt aaggatattc ccaaacggct aagtcaagca cttgatgtga
    50521 cgatacgggg ggaggcctat atgtcgcgtc aggcctttaa gacgatcaat gaagagcgtc
    50581 aggaaaatgg tgagccagaa tttgccaatc caagaaatgc agcggcagga accttgaggc
    50641 agctggatac taggattgtt gccaagcgac agctagcaac ctttttgtat caggaggtag
    50701 gcctagaaac tgctgatagc cagcaaaaga ccttggagcg cttggccgat ttaggctttt
    50761 cggtcaatag ccactatctg ctgtcctcat cgatgaatga catttgggac tttatccaga
    50821 gcattgaagc tagtagagaa gagctacctt atgagattga tggtgtggtg gtcaaggtta
    50881 atcagttggc gatccaagag gaacttggct ttaccgtcaa ggcaccacgc tgggctattg
    50941 cttataagtt tccagcagaa gaaaaggaag ctgagattgt atctgtggat tggacggttg
    51001 gccgaacagg tgtggtcaca ccaacagcta atttgacccc tgtgcagctg gcaggcacca
    51061 ctgtcagtcg agcgaccttg cataatgttg attatatcgc agaaaaggat attcgcattg
    51121 gggatacggt ggtggtgtat aaggctggag atattattcc agctgttttg cgggtggttg
    51181 aggctaagcg tagggatcag gctccaatgc ccattcctac agcctgtcct tcctgccaga
    51241 gtcagctggt gcattttgag gacgaggtag ctttgcgttg cattaacccc ttgtgtccga
    51301 gcttggttca acggagcttg gagcattttg ccagtcgtca ggcgatgaat atcgctggtc
    51361 ttggtccagc ggttgttgaa aagctttatt ctgctggcct ggtgcatgat gtggcagata
    51421 tttaccgact aagcttggag gatttgctga cgctagatgg tatcaaggaa aagtcggctg
    51481 aaaagctctt ggcagctatt gaacaatcaa aggcaaactc agctgaaaag ctcttgtttg
    51541 gacttggtat tcgtcatatt ggcgcaaagg ctagtcgtct gatattagag gcttacggtg
    51601 atttagaggc gctgttagct gtaaccgctg aagagctcgc tcagattgac gggcttggtc
    51661 tagtgatcgg acaatccctg gtgcagtatt ttcagcaaga gcaagccgct cagctgctag
    51721 ctgaattaaa atcagctggg gttaatctgg cttatttagg ccaaaggcct gatcaacagg
    51781 ctgcgctgtt tggtttaacg gtggtattga caggaaaatt agaaaagcta aaccgtaccc
    51841 aagccatgga aaagctagag cagcttggtg ctaaggtaac aggaagcgtt tctaaaaaaa
    51901 cagatttagt ggttgctggc agcgaggcag gctctaagct ggctaaggcc cagcagctgg
    51961 gtatcagaat tgaagatgag gattggttgc tcaatcttta gtgaggtaat aacatgaaaa
    52021 aacaaatgag ggctcgtctg atttacaatc caacctctgg tcaagaaatc atgaaaaaaa
    52081 acgttgcaga ggtgctggat attttggaag gctttggcta tgaaacctct gcctttcaaa
    52141 cgacagcagc taagcactca gccttaaagg aagcaagaag ggcagctaaa gcaggctttg
    52201 acctcttgat tgctgctggt ggagatggta cgatcaacga agtagtcaat ggcattgctc
    52261 ccctagagaa aagacctaag atggcgatta ttccagcagg aaccaccaat gattttgcta
    52321 gggccttaaa ggtaccaaga ggcaatcccg ttgaggccgc taagctgatt ggtaaaaatc
    52381 aaaccatccg catggatata ggacgtgcta aaaaggatac ttattttatc aacatttcag
    52441 ccgcaggaag cctgacagag ctgacctata gtgtccctag tcagctcaaa accatgtttg
    52501 gctacctggc ttatctggct aagggagtgg agctcttgcc tcgagtgagt aatgttccgg
    52561 tgaaaatcac gcatgatcat ggcatttttg agggagaggt atcaatgatt tttgcagcca
    52621 tcactaattc tgttggtggc tttgaaaaga ttgccccaga tgctaagcta gatgatggca
    52681 tgtttaccct tattttgatt aaaacagcca acctgtttga aattgtgcac ctgctgcggt
    52741 tgatcattga cggtggtaag catgttacgg atcgccgcgt cgaatacatt aaaaccagta
    52801 aaatcaccat tgagccccaa tcagataagc gcatgatgat taatttagat ggtgaatatg
    52861 gtggtgatgc gccaattacc ctagaaaact taaaaaatca catcaccttt tttgcaaata
    52921 ctgatttgat ttcagatgat gcccttgtcc tagaccaaga ggagctggaa atcgaagaaa
    52981 tggtcaagaa atttgcgcat gaggtagagg atttagagca gggattggag gaatagggct
    53041 agttatggat aatgcagtta ttgttcatta tcatagttgc aagggacatt attttcaatt
    53101 aagtctatgg caatggcgag atggtaagct gggcaaggac gcttattttt cgaggtttga
    53161 cagctttgga gcagttgctt atctcactta tccagcacct tattttttga gtcatgctta
    53221 tgtgattgta aaggatcagt tttggcagca tcaaaccgtt gattttcgga ttgagcgtga
    53281 ttatggggtt ccaaagactg aggtgtggct tgttgatggt gatcctacgg tttattattc
    53341 gagacaggct gctgtggcta gtcgacatga tggtagatgt gatgtgcatg cctttgatat
    53401 ggctgtcaat agtcaggcct ttgacaagcg ctggggcttt agtggctggc taggctttcg
    53461 ctatcagcct gaggagacgt cttttcgttt gtgggctcca acagcagaaa aggttgagct
    53521 cattctctat gcttcgactg atgagagagc tagtgttgcc aaggttttgc ccatgcagcg
    53581 tgggcagcag tactcgccag atcatcatgc agaaaacaca tgtggtgtgt gggacatcag
    53641 cctaagaggt gattataatt accatgctta ttgctaccgg gtttattatc gcaggcgtac
    53701 ctttagagac actagggatc cttatgcgat cgcaacgaca gcaaatggca aaaggtcaat
    53761 tgtcattgca ccggagcatt taagaccgca gggcttttca gtgaagcagg gtaaggaggc
    53821 tacctggcgc ttagacaatc ctaatcaggc ggtgatctat gaaatgcatg ttcgcgactt
    53881 ttcaaaatca gaaacctcgg gcgttagctt ggctaatcgt ggcaaattta aggggctgat
    53941 tgagacaggc acgcgcaatg cttttggaga ttcaacctgc tttgattatg tcaagtccct
    54001 tggcattacg catattcagc tccagccggt ctttgaccat catcaattct ttgatgaaaa
    54061 tggagattat gcctataatt ggggctatga ccctgaaaat tacaatgttc cagcagccag
    54121 ctttaccagt aatccgcatg agccagctac ccgtatcctg gaattaaagg aggtcattca
    54181 ggcttatcat gatgcaggca tcaatgtgat catggacgtg gtgtacaatc atacctactc
    54241 atcaagagag tcagcctttc agctgacggt tccggattat tattaccgta tgaatcctaa
    54301 tggctccttt caaaatggct ctggctgtgg caatgaaacg gctagtgaaa aggaaatgta
    54361 tcgcaaatac atgcttgatt cgatcctata ttggaccaat gagtttaaca ttgatggctt
    54421 caggtttgat ctgatgggct tacacgatat tgacaccatg aatcttatcc gacaagagct
    54481 agataagatt gacccaagga tacttgtttt tggtgagggc tgggatatgg gagttggtct
    54541 ggcagctgag cagaaggcta aaaaaggaaa tgccagccaa atgcctggaa tcggctttat
    54601 taatgatgat cagcgtaatg cagttaaggg ggcagaggtc tatgggagct tagagaaggg
    54661 ctttgtatca ggtgcaccga cagaaggact tgtagccaag tctattttgg gcagtgatga
    54721 gctggtctct tattgtacgc ctagtcaggt gatcaattat gttgaagctc atgacaacta
    54781 taacctcaat gatttgctgt gggttttgaa tccagaggac agcaagcagg atcatgtcaa
    54841 acgggttcag ctagcttcag ctatgacgat tctcatgcaa gggatttact ttatgcagct
    54901 gggtcaggaa tttttacgaa caaagcttta cccaacaggt caggataagg agctgacaca
    54961 ggcagaccga gaaagggcga tgaattccta caatgcacct gacaatgtga atcaggttga
    55021 ctggagacag gttagcttgg agcgcgaaac ggttgctatt atgaaaaaac taatctatct
    55081 gaaaactaaa acagctttgt tttcataccc atcatttgag caaatcagac agcatgttta
    55141 cattgagcat gctggtgaaa atacgggctt cattagcttt acagtagaag atgaaagaaa
    55201 gtatcgattg attttctcta gttttagaaa ccgcttgcaa tcatctgcta atcatgttat
    55261 aattgaaaca aatgataagc gctttcaaga tagtgagtcc atgctagatg agctgacagc
    55321 gatgatcctt gacatcacac aatagcctga gtgttctcag gttatttttg tttgttgtca
    55381 aggataaaag ggctgtagtt acagttagca gagacctatt aggaccttgc ttatcatatc
    55441 gcttagcgcc ttgaaaaagg gtttaggagt agggaaagaa gaggtgatgg gatggataat
    55501 gacttagcgc tttatacctt tggcacaggt gagaattttc acatacagga ttatctaggt
    55561 gttcatcgga ttaacaatga cacaggcacc agctatgtct ttagggtatg ggcgcccaat
    55621 gcagaggctg tcagcttgat tggagatttt actgattggc agtccaatcc acttgagatg
    55681 agccgaaatg aggctggcgt gtgggaggtt accactagct tgccgcagga aggagatatt
    55741 tataagtatt gggttaggcg ccaaggtggt cagcttgttg aaaaaattga tccagtggcc
    55801 tttctatttg aagctagacc aggaacgggt gctattgtca aaacccttcc agccaaaaaa
    55861 tggcgtgata gcttatggat gggacggcga aagcgttttg gctttaggca gcgtccggtt
    55921 aatatctatg aggttcatgc ccattcatgg aaaaaagacg aaaacgcaag gccctatgac
    55981 tttagcaagc taaaagaaga gctcattccc tatctcaaga gcatgcacta cactcatgtt
    56041 gagtttatgc cggtcatggc tcacccctta gatatgagct ggggctatca gctgatgggc
    56101 tactttgcct ttgagtcaac ctttggaagc ccagaagcct ttcaggattt tgttgaggcc
    56161 tgtcatctta ataatattgg tgttttgatt gattgggtgc cgggacattt tacacaaaat
    56221 gatgacgcct tagcttattt tgacggtaca gctacctatg aatatcagga tcaccatcgt
    56281 gctcataatt atggctgggg gccctaaatt ttgatttggg taaaactcag gtacagtcct
    56341 ttttgatttc aagtgccctt ttttggctgg aggcttatca tgttgacggc attcgagtag
    56401 atgctgttag caatatgctt tacttggatt atgatcaagg cccttggact ccgaatcaat
    56461 acggtggcaa ccaaaacctt gaggggatag cctttcttca aaaattaacc acagttatca
    56521 aggaaaaaca ccctgatgtg atgatgattg cagaggaggc gacctcagct accccaataa
    56581 ccagccctgt tgcagaaggg ggactaggct ttgattataa gtggaatatg ggctggatga
    56641 atgatattct taggttttac gaagaggatc cttattaccg aaaatacgat ttcaatctct
    56701 tgacctttag ctttatgtat tgctttaagg agcattacat tttacccttt tctcacgatg
    56761 aggttgttca tggcaaaaaa agcctcatgc ataaaatgtg gggggaccgc tacaatcaat
    56821 ttgcaggcct aagaaatctt tacacctatc aaatctgcca cccaggcaag aagctgcttt
    56881 ttatgggatc tgagtttgga cagtttttgg aatggaaata cgatcatcaa ttagagtggc
    56941 aaaatttaga ggacgagctc aatgccaaaa tgcagcattt cacagccagc ctaaatcagc
    57001 tatataagga ccatagcatg ctgtggcaaa atgatgaaac ctatgacggc attgatatta
    57061 ttgatgcaga caataaggac gaatcagtct tgtcgttttg tcgtcaaaac aataaaggag
    57121 agctcctgct ttgtgtcttt aacatgacac ctgttgaaag accaggcttt accataggtg
    57181 tgccgatagc aggtctttat caagaaattt tcaatacaga gcttgaggcc tttggaggtg
    57241 tctggaagga gcacaatccc ttaaccaaca cagtagccaa gaaatggaag acttatccgc
    57301 agaccttgag ctttaccctg cctgcactag gagcaagcat ctggaaaatc aagcgtcgtc
    57361 agaagcaata agctattcat tgcttactta gctgtttcaa ccaaaagaag tcactacagt
    57421 catgaaagga taacgaaatg aagaatggaa tgttagccct catattagca gggggacaag
    57481 gaactcgctt aggaaaattg acacagagca ttgcaaagcc tgctgtgcaa tttggaggtc
    57541 ggtatcgtat cattgatttt gccctatcca attgtgctaa ctcagggatt cataatgtgg
    57601 gggttatcac ccagtaccag cctcttgcct taaataatca tattggcaat ggttcgtcat
    57661 ggggcttaga tggtattaat tctggcgcta cgattttaca gccctactct gcaacagagg
    57721 gaaatcgctg gtttcaagga actagccatg ctatctatca aaatattgat tatattgata
    57781 gcattaaccc tgaatatgtg ctgatcctgt ctggtgatca tatttacaaa atggactatg
    57841 atgacatgct tcagacgcat aaggctaata tggctagctt gactgttgct gtgattgatg
    57901 ttcctctaaa ggaagccagt cgatttggca ttatgaacac agataccaat gaccgcattg
    57961 tcgaatttga agaaaagcct gccaatccaa aatcaaccaa ggcttcaatg ggtatttata
    58021 tctttaattg gcagcgcctt cggaccatgc tggttgacgc agaaaaaaac aacattgata
    58081 tgtctgactt tggtcagcat gtgattccgt cttaccttga gtctggcgag cgtgtctaca
    58141 cctataactt taaaggctac tggaaggacg tcggaacgat tgagtctctc tgggaagcca
    58201 atatggaata catcggtgag gaaaatgccc tagacagtcg tgatcgttct tggaagattt
    58261 attctaaaaa ccatatcgct ccaccaaact ttatcacaga ggacgccgag gtcaaggatt
    58321 ctctggtagt agatggcagc tttatctctg gtaaggtcaa ccattctatc ttgtctacca
    58381 atgtgcaggt aagaaaggga gccgaggtta aggattcctt tatcatgagc gatgttatca
    58441 ttggtgaggg tgcaaggatt acacgagcta ttattggtga gggtgcagtc attggtgatc
    58501 atgtgatcat tgatggcagc aaggacgttc aagtcgtagg ctataatgaa gtagtggggg
    58561 taccaaatga agattgataa atattctgcc attctaggca gctcaattgg ctttgctgaa
    58621 atgaaggggc taacagacac aagaccatta gccaacctac cctttgatgg gaaataccgg
    58681 ctcattgatt ttcaattgtc caaccttgcc aatgcaggtg tccgtagcat ctatggtatt
    58741 tttcgtgggc aaaatatccg ctcagtgttt gatcatatca ggtcaggtcg tgaatggggg
    58801 cttaattcct tactaagtca ttatttcctt ggcttttata acaccaagga ggattctaaa
    58861 gaggctgaca aggactatta tcagcagatt ttgacctatt taaagcgctc agggtcagat
    58921 cagaccattt acatgagctg tgatattctc tgcaatattg agcttgggca ggttattcat
    58981 ctgcacaatg ccaaccatcg caacattacg gttgtctaca agaaaatgcc gaccaaggcc
    59041 atctctaagg ctaacgatat tttagatatt gacgagacag atactgttgt tgacaggcga
    59101 agtctgtctg aggggcagga ggttgaaaaa atgtcagcag gcatttacat cgtcaatacc
    59161 ccatggttaa ttgaacagat ggaaaaagaa gccgaaaaag aaaaccctca aaagctacgc
    59221 ttcctcttac gtgatttgat tgtgtcagag ggcgctcttg gctttgaata tactggctat
    59281 cttgccaata ttcactctgt taaatcttat tttgatgcca atatggacat gctggatccg
    59341 cataagtttt attcactatt atatgctaat cagaaggtct acacgcgtgt caaaaatgaa
    59401 gagtcaacct attttgatgc ggcttctgag gtgaacaatg cccaatttgc ttcaggaagc
    59461 attgtcaagg gctatgtcga gcactcaatt gtctctcgca attgtcgcat tacctcacag
    59521 gcacgtgtta caaatagtat tttattgcca aaggcagtga ttggtgaggg tgctgtcatt
    59581 gattatgcta tcattgataa atccgtaagg gttgcaccag gtgttactat tagaggaagc
    59641 gctgaggagc caatagttgt tgccaagggg actgaggttg ttgaggatat gataaaatga
    59701 agataatgtt tgttgcagca gagggagctc cctttgctaa gacaggtggc ctaggcgatg
    59761 tcattggggc attgcctaaa tcacttgtta aaaatggtca tgaggtgtct gtgatactgc
    59821 cttattatga cgtggttgat caagcctttg gtcagcaggt tgaggacgtc ttgtattttt
    59881 atacgcaggt tggctggaga cgccaatacg tgggcattaa aaagcttgtc aaggataagg
    59941 tgacctttta ctttattgac aatcaaggtt atttctttag aggcaggatc tatggtgatt
    60001 gggacgacgg tgagcgcttt gcctatttcc agctggctgc catagaagca atggagaaaa
    60061 tcggggttat tccagatatt ttgcatgtgc atgattacca taccgctatg attcctttcc
    60121 tattgaaaga aaaataccat tggattcagg cctatcaagc gattcggaca gtttttacca
    60181 ttcataatat cgcatttcaa gggcagtttg atcctggcat gctaggcgat ttgtttgatg
    60241 ttggtataga gcgctacgag gatggcaccc tgcgttggca tgattgcttg aattggatga
    60301 aagcagcagt cctatatgca gatcgggtaa ccactgtctc accctcttat gcgcatgaaa
    60361 ttcagacacc agcctttgga caaggcttgg atcaagtcat gcgaatggag gcaggcaagc
    60421 tatcaggcat tgtgaatggt attgacactg acttatttaa cccagcaagg gatcctcatt
    60481 tgcctgcttc attttcagca gaagacctat caggcaaggc ggctactaaa caggccttgc
    60541 aggagcggtt aggattacca gtcagggcag atgttccatt gattggtatg gtttcgcgct
    60601 tgacggatca aaagggcttt cagcttgttc ttgaggaatt accgcatatc ttgcagcagg
    60661 acgttcagct tgtcttgtta ggaacaggtg accctgatta tgaggctgcc ttttcatggt
    60721 ttgccaaggc ctatccagaa aaactgtctg ctaatattac ctttgatctg ccattagctc
    60781 agcagattta tggggcctgt gatctctttt taatgccaag tgcttttgag ccctgcggac
    60841 tttcgcaaat gatggctatg agatatggcg cgataccgat tgtccatgag atcggcggct
    60901 tgaaggatac tgttgcctcc tacaatgctt atgaaaagac tggaactggt tttggctttg
    60961 atcagttttc aggattttgg ttaacgcaga cgctcttgtt tgcccttgat atttaccata
    61021 accacaagga ggattggcag actattcaac aacatgccat gaccaaggat ttttcatggg
    61081 atacagccag tctggcctac cttgatttat ataaaagctt actataacac agaaaaggaa
    61141 tgggaatgca cgtcacaaaa gaacaattta ttcgagattt taaagatacc ttacatgagg
    61201 aacaattgat caaggttcct gccgcaacag ctgctgagct tttcacctca ttagcaaagc
    61261 ttatccgtaa atactataca gatacttgga ttgaaaggaa tcgttcctta accgaacagc
    61321 agcaaaaaat tgcctattat ttttcgatcg aatttttacc aggaagaatg ctagaaacaa
    61381 atcttcttaa tttaggcatt cttgatacag ttaaagaagc ctttgctgac ttgggaattg
    61441 attttcaagc agtgaagcat gcagagcacg acatggctct aggcaatgga ggtctaggac
    61501 gtttggcagc tgcctttatg gattcgctag cgacaacagg ctatccaggc tttggaaatg
    61561 ggctgcgtta tcgttatggg ctgtttaagc aacggattgt gaatggttat caggtagaat
    61621 taccagattc ttggtttggc tctattggta atgtctggga gatcagaaag gatcatgaca
    61681 ttgtagacgt caagctcttt gggaatgttt acctaaaagc caatcaggac ggtaagctag
    61741 cgccaatcta tgagggagct caggttttga gagctgttcc ctacgatgtt cctcagattg
    61801 gctttgaaaa tgatgtgatt aacaatcttc gcctctggga cgtagaaatc ccagaagaac
    61861 atgagcttga ttacccaacc atcgagtcaa gacgggcagt caaggacatt actgccattt
    61921 tgtacccaga cgacagcagc tatgaaggca aaaagcttag attgatccaa gaatatttca
    61981 tgaccagcgc aggcatccaa accattatca aatcctattt aaagcagggc ttgccactta
    62041 ctgagcttca tcaaaaggta tctgttcata tcaatgatac ccacccagca gtagctccag
    62101 cagagcttat gcggctcttg attgacgact atggcttaga atgggtagac gcctgggcga
    62161 caaccgtaaa aaccatgagc tataccaatc atacgatttt gtcagaagcc ttagaaaaat
    62221 gggacgcaga gctctttaag actgtgctgc cccgcgttta tcaaatcatt ttagagattg
    62281 atcatcgctt tgttgctgaa atggcgcaaa agggtattga tcctcagatc attgaaaaca
    62341 ctagaatcgt taaggacaac cagatttata tggctaatct tgccattatt ggtggctatt
    62401 cggtcaatgg cgttgccaag ctacatacag agttgttaaa gacagatacc cttaaggact
    62461 tttatgcctt gtatcctgaa aaattcaaca acaaaaccaa tggtatcgtg caaagacgtt
    62521 ggacacagat tgctgcgcca gagctatcag cagctattga ccgcacgatt ggcaaaggct
    62581 ggcgcaagga tattcaccag cttcgacaat tgagtcaatt tacagaagat ccagctgtgc
    62641 taaatgattt ttatcaggta aaacaagcag ctaagcagcg cctagccagg tatatcctgg
    62701 aaaaaacagg tcttgaggtt tcaacagagg ctatttttga tgtgcaggtc aaacgcctac
    62761 atgcctacaa gcggcagctc ctgaacgtcc tgcatattat gaagctttac cttgatttga
    62821 aggctaatcc agatttagat atggtgccta gagtctttat tttcggcgca aaggctgcac
    62881 caggctatca ttttgccaag tcggtgatca aaatcatcaa tgagctggct aatctcatta
    62941 accatgatac cagtctcaaa ggaaagctaa aggttgtttt tcttgaaaat tataacgtga
    63001 gtctagcaga gctcattatc cctgcggcag atatttcaga gcagatttca ctggcctcca
    63061 aggaagcctc aggaacatca aacatgaaat ttatgatgac tggtgctatc accctagcga
    63121 cccttgatgg ggcaaacatt gaaatcaaag acgaggtcgg agaggaaaac attgtgatct
    63181 ttggtatgga taaggatcag gtctatgacc actatgccaa gcatgattat tattcaagag
    63241 gcctatatga gagcgaccct cagattaaag cagtagtcga cgcttttgtc aatggcacca
    63301 ttccaaatag tcaacacgaa ggtatggaaa tctatgatgc cctaatcacg cataatgatg
    63361 aatacttctt gctagaagac ttttcttcct atgtaaaagc acaggctaag attgatcggc
    63421 tctaccgcca aaaggataga tggtcaaaaa tgtcgctcat caacattgcc cattctgaca
    63481 agtttacatc agatgatacc atcacccagt atgccaagga catttggcag ctaaaacgct
    63541 aatccatcaa ggaagaaaaa gcattagtta ccttagattg aagagagtgt cttttgagac
    63601 cattttcttc aatctttttt gattgcaaaa gaccttggga atcagatcag ctgcctgcct
    63661 aatactttgg cctatcaagg tattttggaa tttgttaatc tttttgttat aatagtggtg
    63721 tgaagctatt ttttaaatga aaaagccaac acttcaagat ggtgttaaag taaggttagt
    63781 attagtctaa gaaagcgtaa ccacattaaa gaaagctgtt gacattctca attttaagga
    63841 atagaataac aaagtaaaaa atttttaaaa ggagtattct attatgaatc ctattttcgc
    63901 attggctctt gcctgctttg gtgtatcact tgccgaaggc tttttgatgg ctaatctctt
    63961 taaatcagcg tcacgccaac cagaaattat cggtcaatta cgttccttga tgatcctagg
    64021 tgttgccttt attgaaggta ccttcttcgt tacccttgtt atggccttca ttctaaaata
    64081 acagcctatt tgatatagaa aaggagggta ttaaatggaa gaagctaaag taccgatggt
    64141 agagcttggt ccaataacct ttaatttgac cctacttgct gtttgtattg ttactatcct
    64201 actgatattt ggctttgttt tttgggcaag tcgtcagatg acattaaaac caaaaggcaa
    64261 gcaaactgcg ttagaatatt taatcagctt tgttaatggt attggggaag agcatttgga
    64321 tagtcatctt cagaagtctt attcgctttt actttttacc atttttcttt ttgtggcagt
    64381 tgccaacaac ttgggcttat ttacaaagct agaaacaacc agtggctaca acctatggac
    64441 atcgccaaca gctaatttgg cctttgacct agccctatct ctgtttgtga cgcttcttgt
    64501 tcatatcgaa ggcattagac gtcgtggttt tggcgcttat ttaaaacgct ttgcgacacc
    64561 ttggccaatg actccgatga acctattaga agaatttacc aacttcctat cacttgctat
    64621 caggctgttt ggtaatatct ttgcaggaga ggttgtgaca ggcttgattg ttcagctggc
    64681 caattatcgc ctgtattggt ggccaattgc tttccttgtt aatatagcat ggacagcctt
    64741 ttccatattt atttcctgca tacaagcctt tgtatttaca aaattaacag caacgtattt
    64801 aggaaaaaaa gttaatgaat cagaagaata agaagggagg acaaacgaat gtcagttaca
    64861 attggtgagc tcattgggaa ttttattctg gtaacaggct ctgtcatcgt cttgttgctc
    64921 ttgattaaag cctttgcttg gggtgctatc gaagctgttt tacaggcacg ctcacagcaa
    64981 atttcacagg atattgacca agcagagcag gcgcgtctca acgcccagca gcttgaaaag
    65041 gaaggtcaag ccaatctaga agccagcaga tcagaggcta gtcagattgt tgaggcagcc
    65101 aaagaaactg gtaaagcaca ggagacacgc attgtagcag aggctacaga agaggcagat
    65161 cgcctaaaag cagcagcgtt gacagatatc gaacacagca agtcagaggc tatttcagcc
    65221 gttaagacag aaatgtcaga tttgacagtt ttactagcag aaaaaattat gggagccaat
    65281 cttgataagg cggctcaaag ccagcttatt gatcgctatc ttgatgattt aggagaggct
    65341 taatgaccaa aaaagaacaa gctcttatcg agcaatatgc aaaaagtctt gtgcaggtct
    65401 gtcaggagcg agacactctt gaagcactgc aggctgatgt gcttgccatt ttagaggttt
    65461 ttaaagctac taatcttgct aagacattgt caagcttagc ggttccacgt gctaaaaggc
    65521 ttgagctagt aaggcagctt caaggagata atatcgttta tctgaataac ttgctagaag
    65581 ttatgctgca aaatgagcgt gaagcttatt tatatcaagt gcttctaagg gttttatccg
    65641 agctggctag tgtctcaaat caatatgacg tgacagttac atcagcagtt cctttaagtg
    65701 aggagcaaaa gcagcgtgtg cgtacagtgg tttcaaagag acttgcagta aagacaggtc
    65761 gcttaatcga aaaggtagat ccttctttaa ttggaggatt tatgattagc gtcaataata
    65821 aggtaattga tacaagcatt cgtcgtcaat tacaagcatt taaaatgaat ttaaaataga
    65881 aagtggtgtg acttttggca attaatgcac aagaaattag cgctttaatt aaaaagcaaa
    65941 ttgagaactt ccagccaaat ttcgatgtca cagaaactgg agttgttacc tatattggtg
    66001 atgggattgc acgtgctcgt ggcttagaca atgcgatgag tggcgagctt cttgaatttt
    66061 caaatggtac cttcggtatg gctcaaaacc tagagtcaaa cgatgttggt atcattattc
    66121 ttggtgattt ttcaacgatt cgtgagggtg atgaagtcaa acgtaccggt aaaattatgg
    66181 aagtgccagt cggtgaagct ctcattggac gtgtggtcaa tccacttggt cagcctgttg
    66241 atggcttagg tgacattgag acaactggct ttaggcctgt tgaaactcca gctcctggtg
    66301 ttatgcagcg taagtctgtt tttgagtcct tacaaaccgg tctaaaggct attgatgctt
    66361 tggttccgat cggtcgtggc cagcgcgagc tgattatcgg tgaccgtcag acaggtaaga
    66421 cgtctgtagc cattgatgcc atcttgaatc aaaaggggca ggacatgatt tgtatctatg
    66481 tcgctattgg tcaaaaggaa tcaacagttc ggacacaggt tgaaacccta cgtcgttatg
    66541 gtgctttgga ttataccatt gttgtaacgg cttctgcttc acagccatca cccttgctgt
    66601 ttattgcacc ttatgctggt gttgcgatgg cagaagagtt tatgtacaat ggcaagcacg
    66661 ttttgattgt ttatgatgac ctgtctaagc aggcggtagc ttatcgtgaa ttgtcgctct
    66721 tgcttcgtcg cccaccaggt cgtgaggcct atccaggaga tgttttctac ctgcatagcc
    66781 gcttgcttga gcgctcagct aaggtgtctg atgacttagg tggtggctca attacagcct
    66841 taccatttat tgagacgcag gctggggata tctctgccta cattgcgaca aacgtgattt
    66901 cgattacaga tggtcagatt ttcttgcaag aggatctctt taactcagga atccgcccag
    66961 ctattgatgc tggctcgtca gtatctcgtg tcggtggctc tgcacagatc aaggctatga
    67021 aaagggttgc agggactttg cgtcttgacc tagcctctta tcgtgagtta gaagccttta
    67081 cacaatttgg ctcagatcta gatgcagcaa cgcaagcaaa attaaatcgt ggtcgtcgta
    67141 ctgttgaaat cctaaagcag ccactgcaca agcccttgcc tgttgaaaag caggtggtca
    67201 ttttgtacgc tttgacgcat ggatttttag atgatgttcc tgtagatgat attttagcct
    67261 ttgaagaagc actttatgac tactttgatg cgcattatga tcacttattt gaaacaatcc
    67321 gtacaaccaa agaccttccg caggaggctg agctggacgt tgctattcag gccttcaaag
    67381 cacagtcaaa ctttaaataa aagagggggg tactagtatg gcaggctctc taagtgaaat
    67441 taaggctaaa atcatttcaa ccgaaaaaac aagcaaaatc actagcgcca tgcgtatggt
    67501 ttcttctgca aagcttgtta aatctgagca agcagctcgt gattttcaaa tctatgcttc
    67561 aaagattcgt cagattacaa cagacttact gaaatcagac ctgacaacag gctcagataa
    67621 tcccatgctg gtgtctcgtc ctgtgaaaaa gacaggctat attgttatta cctctgataa
    67681 aggactggtc ggtggttaca attcaaaaat cttaaagtcc attatggaca tgattcagga
    67741 ataccatgcc gctggcgatt atgagattat ctcaattggc agcatcggct cagatttttt
    67801 taaggccaga ggtatgaatg ttgcctttga gctgcgcggc ctagcagatc agccaagctt
    67861 tgatcaggtc ggaaggatta tctctcagtc tgtaggtatg tttgtcaatg agatttttga
    67921 tgagctgtac gtctgctaca atcaccatgt caatagcttg acgagccagg ttcgggttca
    67981 gcgcatgctg ccgatttctg atttggttgc cgaggaggcc gcagaagaag gtgtcactgg
    68041 atttgaatta gagccaaacc gtcatgtgat tttggagcag ctgctgccgc aatttactga
    68101 aagcttaatt tatggtgcga ttattgatgc aaaaacagca gagcatgctg ctggcatgac
    68161 tgcaatgcag actgccactg acaatgccaa gcatgtgatc aatgatttga ccatccagta
    68221 caatcgtgcg cgtcaggcgg ccattacaca agaaattaca gaaattgtag ctggtgctaa
    68281 tgcacttgaa taagcttatt gtatgctgat agcgctctag cagagaccta ttagcactta
    68341 atgtcatctt caaagctaga tgacatttgg gattaatgag ctaggggcct tttaccctta
    68401 gctactcgaa tttagaaaaa ttcagcttaa tcccctacta tcgaatataa ggagaaaaac
    68461 atgagctcag gcaaaattgc tcaggttgtt ggtccagttg tagacgttgt gtttgcgagt
    68521 ggggacaaac taccagagat taataatgcg ttgatagttt ataaagatgg cgataaaaag
    68581 caaaaaatcg ttctcgaggt tgccctagag cttggagacg gtatggtacg tacaattgct
    68641 atggaatcaa ccgatgggct tacacgtgga ttagaggttc ttgatactgg tcgtgccatt
    68701 agtgtaccag ttggtaaaga gactctaggt cgtgttttca acgttcttgg tgaaaccatc
    68761 gacctagaag caccatttgc agatgatgtt aatcgtgaac cgatccataa aaaagcacca
    68821 gcctttgatg aattgtcaac atcatcagaa attcttgaaa caggtatcaa ggttattgac
    68881 ctgcttgccc cttacttaaa gggtggtaag gtcggtcttt tcggtggtgc cggagttggt
    68941 aaaaccgttc ttatccaaga attaatccac aatatcgctc aagagcatgg tgggatctcg
    69001 gtatttaccg gtgttggtga gcgtacgcgt gaaggaaatg acctttactg ggaaatgaag
    69061 gaatcaggcg ttattgaaaa aacagccatg gtttttggtc agatgaatga accaccagga
    69121 gcccgtatgc gtgttgcctt gaccggcttg acaattgctg aatatttccg cgatgttgaa
    69181 ggccaagacg tcctgctctt cattgacaat attttccgct ttactcaagc aggctcagag
    69241 gtatcagccc ttctaggtcg tatgccttca gccgttggtt accagccaac acttgccact
    69301 gaaatgggac aattgcaaga gcgtatcacc tcaacgaaaa aaggctctgt tacctctatc
    69361 caagccatct acgtgccagc tgatgactac actgatccgg cgccggcaac agcatttgct
    69421 cacttggatt ctacaactaa ccttgagcgt aagctgacgc agatggggat ttacccagcg
    69481 gttgatccac tggcttcaag ttcacgcgcg ctgtcaccag aaattgttgg tgaggagcac
    69541 tatgcagtag ccacagaggt tcagcgtgtc ttgcagcgct atcgtgaatt gcaggatatc
    69601 attgctatct taggtatgga cgagctgtca gaagaggaaa agacattggt aggacgtgcg
    69661 cgtcggattc agttcttctt atcgcaaaac tttaacgtcg cagaacagtt tacaggcctt
    69721 cctggctctt atgttccagt tgccgaaacc gttcgtggct tcaaggaaat cctagaagga
    69781 aagcatgacc accttccaga agacgccttt cgtgctgttg gaccaattga ggacgtgatc
    69841 gaaaaagcta agaaaatggg cttttagtga ggtgatgcca tgacacaaat gactgttcag
    69901 gtggttacgc cagatgggat caaatatgat catcatgcta agttcatctc agtaacgaca
    69961 ccagatggtg agatggggat cttacctaac cacatcaatg tgattgctcc tttacaggtg
    70021 catgaaatga agattcgtcg tgtcagtgaa gacgatcgcg ttgattgggt tgctatcaat
    70081 ggtgggatca ttgagatcaa agacaacgtg gttaccattg ttgcagattc agccgaacgt
    70141 gatcgtgata ttgatgttag ccgagcagag cgggcaaaat tgcgagcaga gcgtgacatt
    70201 gcagaggctg aaaccactca tgatattgat gaggtgcggc gtgctaaggt tgctttgcga
    70261 cgtgccttga accgcatcaa tgttagtaaa aaatagtaaa atgagtctaa cctaccaatt
    70321 taaccaagac agagcgagta gcgctgctta ggaaagggtg tagatagact cttttatctt
    70381 tttatagaaa aaataccctc ttt
//
LOCUS       DARYJX010000003        67345 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYJX010000003 DARYJX010000000
VERSION     DARYJX010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67345
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..191)
                     /locus_tag="TU257_000145"
     CDS             complement(<1..191)
                     /locus_tag="TU257_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0833213.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQ"
     gene            478..1692
                     /locus_tag="TU257_000146"
     CDS             478..1692
                     /locus_tag="TU257_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0833214.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            1864..2646
                     /gene="codY"
                     /locus_tag="TU257_000147"
     CDS             1864..2646
                     /gene="codY"
                     /locus_tag="TU257_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL0833215.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            3263..3820
                     /locus_tag="TU257_000148"
     CDS             3263..3820
                     /locus_tag="TU257_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL0833216.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            4294..4596
                     /gene="gatC"
                     /locus_tag="TU257_000149"
     CDS             4294..4596
                     /gene="gatC"
                     /locus_tag="TU257_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL0833217.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            4596..6062
                     /gene="gatA"
                     /locus_tag="TU257_000150"
     CDS             4596..6062
                     /gene="gatA"
                     /locus_tag="TU257_000150"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL0833218.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            6062..7501
                     /gene="gatB"
                     /locus_tag="TU257_000151"
     CDS             6062..7501
                     /gene="gatB"
                     /locus_tag="TU257_000151"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL0833219.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            7730..8674
                     /locus_tag="TU257_000152"
     CDS             7730..8674
                     /locus_tag="TU257_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL0833220.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            8725..8964
                     /locus_tag="TU257_000153"
     CDS             8725..8964
                     /locus_tag="TU257_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0833221.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            9161..10276
                     /locus_tag="TU257_000154"
     CDS             9161..10276
                     /locus_tag="TU257_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL0833222.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            10540..10806
                     /locus_tag="TU257_000155"
     CDS             10540..10806
                     /locus_tag="TU257_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL0833223.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            10821..12158
                     /locus_tag="TU257_000156"
     CDS             10821..12158
                     /locus_tag="TU257_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL0833224.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            12233..12940
                     /locus_tag="TU257_000157"
     CDS             12233..12940
                     /locus_tag="TU257_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0833225.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            12930..13673
                     /locus_tag="TU257_000158"
     CDS             12930..13673
                     /locus_tag="TU257_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL0833226.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            13670..14242
                     /locus_tag="TU257_000159"
     CDS             13670..14242
                     /locus_tag="TU257_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0833227.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            14692..15726
                     /gene="hrcA"
                     /locus_tag="TU257_000160"
     CDS             14692..15726
                     /gene="hrcA"
                     /locus_tag="TU257_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL0833228.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            15771..16340
                     /gene="grpE"
                     /locus_tag="TU257_000161"
     CDS             15771..16340
                     /gene="grpE"
                     /locus_tag="TU257_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL0833229.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            16745..18574
                     /gene="dnaK"
                     /locus_tag="TU257_000162"
     CDS             16745..18574
                     /gene="dnaK"
                     /locus_tag="TU257_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL0833230.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            18731..19867
                     /gene="dnaJ"
                     /locus_tag="TU257_000163"
     CDS             18731..19867
                     /gene="dnaJ"
                     /locus_tag="TU257_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL0833231.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            20187..20978
                     /locus_tag="TU257_000164"
     CDS             20187..20978
                     /locus_tag="TU257_000164"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL0833232.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            21058..21492
                     /locus_tag="TU257_000165"
     CDS             21058..21492
                     /locus_tag="TU257_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0833233.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            21492..22466
                     /locus_tag="TU257_000166"
     CDS             21492..22466
                     /locus_tag="TU257_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL0833234.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            22524..22748
                     /locus_tag="TU257_000167"
     CDS             22524..22748
                     /locus_tag="TU257_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0833235.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            22943..23929
                     /gene="fabK"
                     /locus_tag="TU257_000168"
     CDS             22943..23929
                     /gene="fabK"
                     /locus_tag="TU257_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL0833236.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            23942..24862
                     /gene="fabD"
                     /locus_tag="TU257_000169"
     CDS             23942..24862
                     /gene="fabD"
                     /locus_tag="TU257_000169"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL0833237.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            24879..25613
                     /gene="fabG"
                     /locus_tag="TU257_000170"
     CDS             24879..25613
                     /gene="fabG"
                     /locus_tag="TU257_000170"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL0833238.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            25629..26861
                     /gene="fabF"
                     /locus_tag="TU257_000171"
     CDS             25629..26861
                     /gene="fabF"
                     /locus_tag="TU257_000171"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL0833239.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            26863..27336
                     /locus_tag="TU257_000172"
     CDS             26863..27336
                     /locus_tag="TU257_000172"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL0833240.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            27333..27755
                     /gene="fabZ"
                     /locus_tag="TU257_000173"
     CDS             27333..27755
                     /gene="fabZ"
                     /locus_tag="TU257_000173"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL0833241.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            27789..29153
                     /gene="accC"
                     /locus_tag="TU257_000174"
     CDS             27789..29153
                     /gene="accC"
                     /locus_tag="TU257_000174"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL0833242.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            29162..30028
                     /locus_tag="TU257_000175"
     CDS             29162..30028
                     /locus_tag="TU257_000175"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL0833243.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            30025..30795
                     /locus_tag="TU257_000176"
     CDS             30025..30795
                     /locus_tag="TU257_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL0833244.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(31027..32304)
                     /gene="serS"
                     /locus_tag="TU257_000177"
     CDS             complement(31027..32304)
                     /gene="serS"
                     /locus_tag="TU257_000177"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL0833245.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            32904..33956
                     /locus_tag="TU257_000178"
     CDS             32904..33956
                     /locus_tag="TU257_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL0833246.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            complement(34277..34660)
                     /locus_tag="TU257_000179"
     CDS             complement(34277..34660)
                     /locus_tag="TU257_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL0833247.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(34794..35705)
                     /locus_tag="TU257_000180"
     CDS             complement(34794..35705)
                     /locus_tag="TU257_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0833248.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(35721..36530)
                     /locus_tag="TU257_000181"
     CDS             complement(35721..36530)
                     /locus_tag="TU257_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL0833249.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            complement(36701..37693)
                     /gene="manX"
                     /locus_tag="TU257_000182"
     CDS             complement(36701..37693)
                     /gene="manX"
                     /locus_tag="TU257_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL0833250.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            complement(38045..38856)
                     /locus_tag="TU257_000183"
                     /pseudo
     CDS             complement(38045..38856)
                     /locus_tag="TU257_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            39115..40575
                     /locus_tag="TU257_000184"
     CDS             39115..40575
                     /locus_tag="TU257_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL0833251.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            40941..41384
                     /gene="tsaE"
                     /locus_tag="TU257_000185"
     CDS             40941..41384
                     /gene="tsaE"
                     /locus_tag="TU257_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL0833252.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            41377..41904
                     /locus_tag="TU257_000186"
     CDS             41377..41904
                     /locus_tag="TU257_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833253.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            41905..43167
                     /locus_tag="TU257_000187"
     CDS             41905..43167
                     /locus_tag="TU257_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0833254.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(43337..43633)
                     /locus_tag="TU257_000188"
     CDS             complement(43337..43633)
                     /locus_tag="TU257_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL0833255.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(43630..44049)
                     /locus_tag="TU257_000189"
     CDS             complement(43630..44049)
                     /locus_tag="TU257_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL0833256.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            complement(44502..44945)
                     /locus_tag="TU257_000190"
     CDS             complement(44502..44945)
                     /locus_tag="TU257_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833257.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            45482..46207
                     /locus_tag="TU257_000191"
     CDS             45482..46207
                     /locus_tag="TU257_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833258.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            46211..47245
                     /locus_tag="TU257_000192"
     CDS             46211..47245
                     /locus_tag="TU257_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833259.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            47308..48099
                     /locus_tag="TU257_000193"
     CDS             47308..48099
                     /locus_tag="TU257_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL0833260.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            48099..48734
                     /gene="trmB"
                     /locus_tag="TU257_000194"
     CDS             48099..48734
                     /gene="trmB"
                     /locus_tag="TU257_000194"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL0833261.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            48794..48880
                     /locus_tag="TU257_000195"
     tRNA            48794..48880
                     /locus_tag="TU257_000195"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48828..48830,aa:Ser,seq:gga)
     gene            complement(48927..50006)
                     /locus_tag="TU257_000196"
     CDS             complement(48927..50006)
                     /locus_tag="TU257_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0833262.1"
                     /translation="MAFYRKLDSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AETDLNTLTADLLDITVLDYNKRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGEKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADEAIVRSQKP
                     AKEESEKFMEESEYLAFIKTAKEKIKYPSYLTTYIIAITGLRFAEAQGLTWKDIDFDN
                     GYVDVNKTFDYSISQNFRPTKNEQSIRKVPIDNNSVELLKYFKDNHYQDNKLSRICFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKIDG"
     gene            complement(50125..50676)
                     /locus_tag="TU257_000197"
     CDS             complement(50125..50676)
                     /locus_tag="TU257_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833263.1"
                     /translation="MDITKLKGFAIAAAGKAKDGAIKANELRKKASQESKMILPPALN
                     LGLGTPTAIRKTIDGKYYIGFYSETPELYEFVNLQFDGSRIIEKTVTKGKTTQRGRSG
                     SVLGGAAIGTVLAPGVGTIVGGMTGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEVKTLKTKLTQAQYVNVNNFFK"
     gene            complement(50687..51070)
                     /locus_tag="TU257_000198"
     CDS             complement(50687..51070)
                     /locus_tag="TU257_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0833264.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMVKEELEFLIS"
     gene            complement(51084..51443)
                     /locus_tag="TU257_000199"
     CDS             complement(51084..51443)
                     /locus_tag="TU257_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0833265.1"
                     /translation="MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTA
                     NTDPIEKIANYFNVSTDYLLGRTDNPKIAQDGHASVAIDLKKDAEETFFFDGHELNDE
                     DIDLITSILETRIKNRK"
     gene            52199..52390
                     /locus_tag="TU257_000200"
     CDS             52199..52390
                     /locus_tag="TU257_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833266.1"
                     /translation="MSDNTVAVEKIKKYLLDNKLKQVDLAVTYNKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            52411..52641
                     /locus_tag="TU257_000201"
     CDS             52411..52641
                     /locus_tag="TU257_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833267.1"
                     /translation="MLNAILERNLMTDAEKQNYDALFINIFERLEKLEEGYDFSSVAT
                     TTGVQNSGGVQYRECQEDGTVVKTVSKRSLGY"
     gene            52707..52982
                     /locus_tag="TU257_000202"
     CDS             52707..52982
                     /locus_tag="TU257_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0833268.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKVKVMKMINNETETYPLELNKKQVS
                     KMFGIDPKTFDARFNSHKDFPRIETGGREKYPRDLVIEWYHRNWSIT"
     gene            52979..53149
                     /locus_tag="TU257_000203"
     CDS             52979..53149
                     /locus_tag="TU257_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833269.1"
                     /translation="MNKLELFLLATTIVLAIIARVQYEIIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            53142..53345
                     /locus_tag="TU257_000204"
     CDS             53142..53345
                     /locus_tag="TU257_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833270.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            53342..53728
                     /locus_tag="TU257_000205"
     CDS             53342..53728
                     /locus_tag="TU257_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833271.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELPSLNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDRR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            53725..53877
                     /locus_tag="TU257_000206"
     CDS             53725..53877
                     /locus_tag="TU257_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833272.1"
                     /translation="MNISIKLIGETLAGLNDILRQGGLSCSQNQALADAVFILTALKQ
                     VIEERK"
     gene            53874..54077
                     /locus_tag="TU257_000207"
     CDS             53874..54077
                     /locus_tag="TU257_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833273.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            54165..54464
                     /locus_tag="TU257_000208"
     CDS             54165..54464
                     /locus_tag="TU257_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833274.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            54464..55621
                     /locus_tag="TU257_000209"
     CDS             54464..55621
                     /locus_tag="TU257_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL0833275.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKTFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGALEKLIGKTTFADLLAEVIDKPQGKPVLVPEKDKRPAINSLEQAIKDFE"
     gene            55635..56198
                     /locus_tag="TU257_000210"
     CDS             55635..56198
                     /locus_tag="TU257_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL0833276.1"
                     /translation="MTTTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            56241..58163
                     /locus_tag="TU257_000211"
     CDS             56241..58163
                     /locus_tag="TU257_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEL0833277.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKAITGLANPNSRAQLLPWLKEHGYSANGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            58168..60552
                     /locus_tag="TU257_000212"
     CDS             58168..60552
                     /locus_tag="TU257_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0833278.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVCDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETIVAIKAQA
                     FSSEVFTESDLNKIVLVNGVYDLRDNSFKTKFDPELHARSSHPVAYAPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRNALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRIKGEF"
     gene            60919..61194
                     /locus_tag="TU257_000213"
     CDS             60919..61194
                     /locus_tag="TU257_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL0833279.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
     gene            61191..62513
                     /locus_tag="TU257_000214"
     CDS             61191..62513
                     /locus_tag="TU257_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0833280.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIVYSWTLRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLVN
                     KLLQMANGAIYDADKTTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGRIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            62514..62681
                     /locus_tag="TU257_000215"
     CDS             62514..62681
                     /locus_tag="TU257_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833281.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAA
                     VKEKYTREWKK"
     gene            62678..62851
                     /locus_tag="TU257_000216"
     CDS             62678..62851
                     /locus_tag="TU257_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833282.1"
                     /translation="MTKQELIEEIEDEINDIDLLIDDYQYEIDELERDIDELDTQKDI
                     LKRKLDNLLESVE"
     gene            62851..63120
                     /locus_tag="TU257_000217"
     CDS             62851..63120
                     /locus_tag="TU257_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833283.1"
                     /translation="MTEQQMIDCLLYELAKKDKAIKNKSIIIAVLTAVLCLVSVLSIA
                     LQNHYEPQITGLQSQLRRTQYQLKRASEDRARQTKRIAELTGNGG"
     gene            63323..63739
                     /locus_tag="TU257_000218"
     CDS             63323..63739
                     /locus_tag="TU257_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL0833284.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            63829..64281
                     /locus_tag="TU257_000219"
     CDS             63829..64281
                     /locus_tag="TU257_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL0833285.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            64271..65548
                     /locus_tag="TU257_000220"
     CDS             64271..65548
                     /locus_tag="TU257_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0833286.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            65564..67096
                     /locus_tag="TU257_000221"
     CDS             65564..67096
                     /locus_tag="TU257_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0833287.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            67056..>67345
                     /locus_tag="TU257_000222"
     CDS             67056..>67345
                     /locus_tag="TU257_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL0833288.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEK"
BASE COUNT        19651 a        12718 c        15715 g        19261 t
ORIGIN      
        1 tcctgctcca acttgtcata aatgtagcta tcaaaggttg caacgctttg cagcgcacgt
       61 gtatcaacaa catgggtcaa aatcaaggca gcaccattac gcaaagcgac attaaccccc
      121 ttgtgaaagg ctaattcgga gccatgagag ccatcaatag cgaccatgat acgttcatat
      181 gtttgtgaca tcggtttatc ctcctttgaa ctttatctct atagctatta tacctttttt
      241 gaggagaaat tgaaaacgtt ttaatgattt tctgagctat tgttcaccaa atagcccagc
      301 tattccctga ggtgaggata ccttgagcta gaagctagct tagatagcct tattaatagc
      361 tgctgcttag cttgcttaga gctttggttg agcttttggc attctttaag ctcatagaaa
      421 agtgctttct attttaattg ttttggttta taatatgggt tacgaggtaa tgagactatg
      481 aaaataattg aaaaatcatc aaaattagaa cacgtagcct acgatattcg aggtccagtc
      541 ctggacgagg ctaatcgtat gatagctaat ggtgaaaaga tccttcgatt aaatacaggt
      601 aacccagcag cctttggctt tgaggctcca gatgaggtta ttcgtgattt gattctcaat
      661 gctcgctcca gcgagggcta ttctgatagc aaggggattt tttcagctcg taaggccatc
      721 atgcaatatt gtcagctaaa gggctttcct gatgttgaca ttgatgatat ttatttggga
      781 aatggtgtct cagagctgat ttcgatgtct cttcaagcct tgctcgataa tggtgatgag
      841 gtgctggtgc caatgcctga ctatcccctt tggacagcct gtgtcagcct aggtggtggg
      901 catgcggtgc attacctgtg tgatgaagag gctgaatggt atcctgatat tgctgacata
      961 aaagccaaga tcactgagcg cacaaaagct atcgtcatta tcaatcccaa taacccaaca
     1021 ggtgctctct accctcgaga ggtcttagag gagattgttg caattgccag agagcatcag
     1081 cttatcattt ttgcagatga gatttatgat cgtttggtca tggacggtgg ggagcatatc
     1141 gcaattgcca gccttgcacc tgatgttttt tgcgtgtcaa tgaatgggct gtcaaaatca
     1201 caccgtattg ccggctttcg agtgggctgg atggtcttgt caggccctaa aagacatgtc
     1261 agaggttaca ttgaaggctt gaacatgctg gcaaacatgc gcttgtgctc caatgtctta
     1321 gcgcagcagg tggtgcagac ctccttagga ggacgtcagt ctgttgatga gctcttgctt
     1381 ccgggtggtc gcatctttga gcaacgtaac ttcatttacc aggccattaa tgccattcca
     1441 ggcctatcag ctgtaaagcc taaggcaggc ctctatttgt ttccgaaaat tgatcgaaat
     1501 atgtaccgca ttgatgacga cgaggaattt gtcctacagc ttttgaagca agaaaaggtc
     1561 atgctggtac atgggcgtgg cttcaactgg aaggagcctg atcattttcg cgtggtctat
     1621 ctgccaacag tagaagagct agctgacgtg caagaaaaga tcacgcatgt tctcaagcaa
     1681 tacaagcgct aatatgattc tcatacaaaa attggatcgc gagatccttt ttgtttttca
     1741 gcaaaataag gctctggcct catccgaatt gtaggtataa tagccaattt tctgataatt
     1801 ccttgcaaaa gctagggtcc tttgatataa ttgtaacgca aataattaaa aggaaaagaa
     1861 aaaatgccaa atttattaga aaaaacccgt aagattactt ctattttgca acgttctgta
     1921 gacagcttgg aaacagaact cccctataac actatggctt cacgcttagc agatattatt
     1981 gattgtaatg cttgtatcat caatggtggc ggcagcttac ttggctatgc gatgaagtac
     2041 aagaccaaca cagaccgcgt cgaggaattt tttgaaacaa gacagttccc agatgcttat
     2101 gtcaaggcag ctagtcgtgt ttatgacact gaagcaaacc tttctgtgga aaatgaacta
     2161 acgatttttc ctattgagtc aaaggatatc tatcctgatg gtttaaccac gattgcccct
     2221 atctatggtg gcggcatgcg cttaggtacc ttgatcatct ggcgtaacga caatgaattc
     2281 agtgatgatg accttgtttt agttgaaatc tcaagcactg tggtcggtat tcagctgtta
     2341 aatcttcaaa cagaaaacct agaagaaacc attcgtaagc agacagttgt taatatggca
     2401 atcaacactc tatcttactc tgaaatgaag gctgttgcag ctatccttag tgagctagat
     2461 ggcaatgaag gacgcctgac cgcttcagtg attgcagatc gtattggaat cacacgatct
     2521 gtcatcgtga atgcccttag aaagctagag agtgcaggta tcattgagag tcgctctcta
     2581 ggaatgaaag gcacttatct caaggtgatt aacgaaggca tctttgacaa gctaaaggaa
     2641 ttttaatagc tcagatgcga tcgtctgcta agcccaaggc ttgcctttag ctttgctagc
     2701 tgtgattagt cagagcaggt agtgaaagtg ttagctatga tcaaagtctt gctgcttata
     2761 gagcagccat tcattagcca gagccctgct tggtaagggc tagacttggt ctttatgacg
     2821 gcttatcgga gtttcttagc agctgtggag gacttcacac attattatag cgtcccctca
     2881 aaggttctag cattggctgg cttttgaggg gtattttttg tattttcgct gtgattcagc
     2941 atgagatgaa catgacagat gcatgaaaga tttttagcaa gaaaataagg ctttctgtat
     3001 ttcaatgttc agctatttca ggaatatatc ttattttcat atagaaaaac gttgaaagtg
     3061 tctacttaaa tctatactat agttcagaaa taactgtttt tcgcctttat cgtgtataaa
     3121 tcaatccgct gtcttgacag ctgtcgtgtt tagtggtaaa ctataagtgt ctaatcatac
     3181 tgaatattaa aagcaggctt agttcttatg gcttgctgtc atgcagctaa gagagcataa
     3241 gctttttggg gagggataag ctgtgaaggc cttgatttct attgattaca cgaatgactt
     3301 tgtagctgat gatggtagcc tgacggcagg agcacctgct caggtgattt cagaggcgat
     3361 ggctagcgtt gttgaggctg cctttgaggc cggctactat atcttttttg cgattgatgc
     3421 ccacgaggag ggagatagct ttcatccgga ggcagccttg tttccgccgc ataatattat
     3481 cgggacaagg ggtcgggacc tgtatggtcc tttgatgacc gtatatacca gataccagca
     3541 agatcagcgg gtcttttggc tggataagcg gcattattct gccttttcgg ggactgattt
     3601 ggatattcgt cttcgtgagc gtggcgtcac gacgctggtc ttgacaggtg tgctgacgga
     3661 tatttgtgtc cttcatacag cgattgatgc ctataaattg ggctacaagc ttgagattat
     3721 cacatcagca gtggcgagca attcaacaga aaatcaccag tgggcgctga accactgtag
     3781 gactgtccta ggagcaaagc ttcttgatcg gctttcttag gcgatcgttc gatcagctgg
     3841 gataggctaa tcaagtaagg cagtattagc tgctgcttgg ctcagcgctg atcttaaggg
     3901 cttcttagtg agatcttttg gtcttggcta ggaggctttt tgttattaag tttttcgcta
     3961 atcccagcta cgcatacacg tgaataaaat gcaggtagct atgctctagc cacattgccc
     4021 ttttaacctc atcaattgct caaatgcagt ttagttatag cctggctgtt cttgaaaaaa
     4081 gcaggttgag cttatgaaaa acgttatcag aaaacgtcag ttgccacatg catttgacgt
     4141 gaaatcccag cagtccgcta tggtaaataa agctaattat gatataatgg ttaagactat
     4201 gtaaaattgg gttattcagg ctattatcaa gcgtttgaaa cagcaaggcc ttgtggctga
     4261 tgatggtctg ctttaccttg gataggagaa ttcatgaaaa tttctgaaga agaggttcgc
     4321 cacgttgcgg ccctatcaaa gctatccttt tcagaaagtg aaacaactga gtttgcgaca
     4381 acattatcaa aaatcgttga catggttgaa ttgctaaatg aagtggatac gacaggtgtt
     4441 gccattacca ccacaatggc agacaagaaa aatatcatgc gagctgatat cgctgaggct
     4501 ggagtggatc gcaagctcct gtttcaaaat gttcctgaaa aagaaaatca tttcatcaag
     4561 gtaccagcta ttcttgatga cggaggagat gcctaatgtc ttttaatcat catactatag
     4621 aagaattaca tgagcttctt gttgcaaagg acatttctgc agttgagcta acaaaggcaa
     4681 cccttgagga tatcaaggcg cgtgaggagg ctgtgggttc tttcattacc attgcttgcg
     4741 aggctgcttt aaagcaggct gctgcacttg atgctaaggg gattgatcct gacaatgtga
     4801 tgtcaggaat accactagct gtcaaggaca atatctcaac caaggggatt ctgacaactg
     4861 ctgcttctaa gatgctttat aattatgagc cgatttttga tgcgacagcg gtagctaatg
     4921 cctacgacaa ggatatgatt gttattggta agaccaatat ggacgagttt gctatgggtg
     4981 gctcaacaga aacgtcttat ttcaagaaaa ccaaaaacgc ttgggatcat agcagggttc
     5041 ctggtggttc atcaggtggc tctgcaacag cagtagcttc aggtcaggtt cgcttatctc
     5101 ttggctcaga cactggcggc tctattcgtc agccagcagc ctttaatggt gttgttgggc
     5161 ttaagccgac ctatggggct gtttctcgct atggcttgat tgcctttggc agctcgctag
     5221 atcagatagg gccttttgcg ccaacggtaa gagaaaatgc ccagctgcta tcggtcattg
     5281 cagggagtga ccgcaaggac tcaacctcag cacctgtaca gatcgctgac tacacaatta
     5341 agatcggtca agacatcaag ggcatgaaga ttgcactacc taaggaatac cttggcgaag
     5401 gcattgatcc taagattaag gagacggttt tggctgctgc taagcatttt gagaagctag
     5461 gagctatcat tgaggaggtc agtctgccac atagcaagta tggggtggct gtctattata
     5521 tcatcgcttc atctgaggcc tcatcaaacc tacagcgctt tgatggtatt cgctatggct
     5581 ttcgtgctgc tgatgccaag agccttgagg acatctatgt caagacgcgt agtcagggct
     5641 ttggtgatga ggttaagcgt cgtatcatgc ttggtacctt tagcttatca tcaggctatt
     5701 acgatgctta tttcaaaaag gcaggtcagg ttcggacgct gatcattcaa gactttgaga
     5761 aggtttttgc tgattatgac ttgattttag gaccaacagc accaacagca gcctttgagc
     5821 ttgatacgtt gaatcatgat cctgttgcca tgtatttggc tgatcttttg accattccgg
     5881 tgaatctagc gggcttgcct gcaatctcta ttccagcagg ctttgcagat ggcttgcctg
     5941 ttgggcttca attgatcggt ccaaaatata gcgaagaggt catctatcag gtagcggtag
     6001 cctttgaagc gactactgac taccacaagc agcagcctat gatttttgga ggtgacaggt
     6061 aatgaatttt gaaaccatta ttggacttga ggtccatgtg gagttgaata ccaattctaa
     6121 gattttctca ccttcatcag ctcattttgg agaggatcca aatgccagca ctaatgtgat
     6181 tgactggtct ttcccaggtg tccttccagt gatgaacaag ggagtcattg atgcgggaat
     6241 caaagcagca cttgctctta acatgtctat tcatcagcac atgcactttg accgtaagaa
     6301 ttatttctac ccagacaatc ccaaggccta tcagatttca cagtttgatg agccgattgg
     6361 ctacaatggc tggattgata ttactcttga ggacggctca accaagaaaa tccgtattga
     6421 gcgtgctcac ctagaagagg atgccggcaa aaatacgcat ggtacagatg gttattccta
     6481 tgttgacctc aatcgtcagg gagtgccctt gattgagatc gtctcagagg ctgacatgcg
     6541 ctctccagag gaggcctatg cttacctgac tgccctaaag gaaatcattc agtatactgg
     6601 tatttctgat gtcaagatgg aagaggggtc catgcgtgtg gacgccaata tctccttgcg
     6661 accatacgga caagaggcct ttggtacaaa aacagaattg aaaaacctga actcatttag
     6721 caatgtgcgt aaggggcttg agtttgaggt ggagcgtcaa gccaaaatcc tacgctctgg
     6781 cggtgttatt cgtcaggaga cacgtcgtta tgacgaggca agtaagggaa cgattctcat
     6841 gcgtgtcaag gagggagcag cagactaccg ctatttccca gagccagatt tgccattgtt
     6901 tgagattgat gacgcatgga ttgaggatat gcgtgcagag cttccaagat ttccggcaga
     6961 caggcgagct agctacatta atgctcttgg cttgtcagcc tatgatgcag gtcagctgac
     7021 agcaacaaag gctttgtctg atttctttga gcaggctgtg gcacttggtg gtgatcctaa
     7081 gcaggtgtct aattggcttc agggtgagat ggctcaattc ttaaatgctg agggcaagac
     7141 gattgatcag attgccttga ccccagaaaa tctcgtggaa atgattgcga tcatcactga
     7201 tggcacgatt tcatcaaaaa tcgccaagaa ggtttttgtt catttggcaa agcatggcgg
     7261 ctcagcgcgt gcttatgtgg aaaaggccgg cttggttcaa atttcagacc cagctgtctt
     7321 gattccaatc attcatcagg tgtttgctga caatgaggct gctgtggcag atttcaaatc
     7381 aggcaagcgc aatgctgaca aggcctttac tggttttctg atgaaggcca caaaggggca
     7441 agccaaccca cagatagctc agcaattgtt agcccaagaa ttgcaaaaat tgctggatta
     7501 aggagtcgtt atgactggca ttgagtctga aacagagttt tcaggctctt tatgatggta
     7561 ggctctttag gacaattctg tgataatacc tcgctatccg aagctgtaag aggtagctta
     7621 tcggtctgtt gttaatgact gttaagcagg cttggtgaag tctaggctag agctatcaag
     7681 gtattatgag tggccttatc atggcatgga ttaaaaagag gaagataata tgtcaagaaa
     7741 tggaaaaggc agtaccatga ttttactagc cggaatcgcc tggggtctct caggggtgtc
     7801 agggcaatat ttaattgctc atggggtcgg catcaatgcc ttgacctcac taaggctcat
     7861 tatttcaggg cttgtgctgt cagctatggc ttatgtgcgg caaagagagg ctgtcatcag
     7921 cttactcaag gacaaaaggc ttttaagaga gctgttgatt tacagtctat ttggtctcac
     7981 acttaatcaa tatgcctatc tgcttgctat tcgttactct aatgctggta cagccacagt
     8041 cctgcaatac ctttccccca ttttggtgct ggtctaccta tcgttcaaat caagacgcct
     8101 gccggctgtg ggagagagct gtgctatttg cctagcgatc ctaggaacgg ttatcatggc
     8161 ctgtcatggt gatctttccc atctggcaat caatcctatt ggacttttct gggggctttt
     8221 tgcagcggtg acctatgctt actgtgtcat caagcctgct aagctgattg ccgactgggg
     8281 gagcttgctg attgttggtc ttgccatgct gatgggagga gtgatttttc cgatcctgac
     8341 aagagcatgg cagtacccat tggcaatgac ttatgggaat ctacgggccc tgtttggcat
     8401 tatcggtatt gggacaattt ttgcctacac cttttttcta aagggggctt caatcattgg
     8461 accgatcaag gctaccttgc tggcttcaat tgagccggtt gcctctgtct gctttgcgat
     8521 tatcctgatg aaagagattt ttcaccctat tgatctgtta ggaatggcct tgattttaat
     8581 agcagtgctt gtgatatcgc tgagagactt attgcttact aagagaaaaa agcagcttgc
     8641 tcttaatatc aagcgaccac catcatctga ctgatataag gcaagggtat ggtataataa
     8701 gacaaaacat aaaggagatt tgcgatggtt tggtcattaa ttgttggagc tattatcggc
     8761 atggttgcag gtaggataac agaaaaaagc cattcgatgg gctgtttcac aatgactgct
     8821 gctggtttga taggctctgc agttggtcaa aagctgtttg gcgactgggg tattcagctg
     8881 gcaggcatgg ctgttttccc ttcaattcta ggagcagcta ttgtgataat tgttgcttca
     8941 gcgctctttg gcaaaaaaca ataagccagg agtacttgtg acgttcaaat atataaaaat
     9001 ccttgtatca gtatgatacg aggatttttt ggttatcaga tttgtaaaaa caatcgaata
     9061 tatcagatga taaaaattta aaagaaatat gataaagtct tgactatata tactatttct
     9121 tggtattttt accaaaaaat atggagagag ttaaaaaagt atgagaaaaa cagaaggacg
     9181 ttttcgcaca tggaagtcca aaaaacaatg gctatttgcc ggtgcagtgg tgaccagctt
     9241 gctgctggga gctgcacttg tctttggagg tttattagga agtcttggtg gctcatccca
     9301 tcaagcgagg ccaaaggagc agccagtcag ctcgattgga gatgacgata agtcgcacaa
     9361 gagctcatca gattcaatgg tcagtcggcc accgaaaaag gataacttgc agcctaagcc
     9421 ttcagatcag cctactaatc atcagcatca ggctactagc ccgtcccagc cgacagcaaa
     9481 gagctcaggt catcatggga atcaacctca gtctctcagt gtgaacagcc aaggaaatag
     9541 tagtggacag gcctcagagc ctcaggctat tcctaatcaa gggccttccc agccactggg
     9601 gctgagagga ggtaacagct ctggttcagg tcatcaccat cagccacaag gaaagccaca
     9661 gcacttagat ctaggtaagg ataattctag cccgcagcct caaccaaagc ctcagggcaa
     9721 tagtcccaag ctgccagaaa aaggcttgaa tggtgaaaat cagaaggaac cggagcaagg
     9781 tgaacgaggt gaggctggtc ccccactttc agggttgagt ggtaataatc aaggccgtcc
     9841 ttcgcttcca ggcttgaatg gtgagaatca gaaggaacca gagcaaggtg aacgaggtga
     9901 agccggtccc ccatcaactc cgaatttaga aggaaataat cgtaaaaatc ctttaaaagg
     9961 attagatgga gagaataagc caaaggaaga tttagacggt aaaggcttaa gcggagaaaa
    10021 tgatgaatca ccaaaactta aagacgaaca cccctacaat catggtcgtc gtgatggtta
    10081 ccgagttggc tatgaggatg gatatggtgg caaaaagcac aaaggagatt atcctaagcg
    10141 gtttgatgag tctagtccaa aggaatataa tgactatagt caagggtata atgataatta
    10201 tggaaatggc tatttagatg gtctagctga tagaggtggt aagagaggat acggctattc
    10261 ttacaatccc gactaatctt ctgctatccc ttaattaacc tacaaaaaag ctgggcttcc
    10321 ttagacccag cttttttggc agcttcaaac gtcttatctt ttattagctg ctattatatt
    10381 ataaagtcta aatattaata aacggtatca attggataac aaactctttt ttctggtacc
    10441 cattgttcta tttttgcaag gggctaccag acctcttgtc tctgatagct ttctcttttt
    10501 gtttgtgata aaatataaca catattgagg aggtgtgcca tgaaagctat cattacagtt
    10561 gttggtaagg acaatcaagg gattgtcgca ggtgtttcag gacaaattgc tgcattaggg
    10621 ttaaatattg atgacatttc acagaccgtt ttagatgatt attttaccat gatggccatt
    10681 gtctcaagca gtgaaaagca ggattttgct catctgcgtg aggtgcttca ggcttatgga
    10741 aagcaattgc aggtgacgat taatattcaa agcgcagcga tttttgatgc tatgcataac
    10801 atataaggag cttgatgact atggatatta gacaggttcg tgaaacagtt gagatgattg
    10861 aggagcagca ttttgatatt cgtaccatta cgatgggaat ttccttgctg gattgtattg
    10921 attcggatat tgatagagct gccgctaaga tttaccaaaa gattacgaca aaggcagcta
    10981 atcttgtggc ggttggtgat gacattgcag cagaactagg tattcccatt gttaataagc
    11041 gcgtctctgt aactccgata gcccttattg gggcggcaac agacgcagaa gactacctgt
    11101 cgcttgcaaa agctctggat caggctgcct gtgatatcgg agttgacttt atcggtggct
    11161 tttcagctct tgtgcaaaaa ggctatcaaa agggtgataa gattttgatt gagtctattc
    11221 ctcaggcttt ggctcaaaca cagaaggtct gcgcttcggt caatgttgga tcaacaaggt
    11281 ctggtattaa tatgacagca gttgcagaca tggggcgtat catcaaggaa accgccaaag
    11341 cctctgagat aggggcagca aagctagtag tctttgctaa tgctgttgag gacaatcctt
    11401 ttatggcagg agcctttcat ggtgtcggtg aggcggatac ggtgattaac gttggtgttt
    11461 caggacctgg tgtggtcaaa agagccttgg aaaaggttcg tggtgaaagc tttgacgttc
    11521 tagccgagac cgtcaaaaaa acggccttta aaatcacgcg tatcggtcag ctagtgggac
    11581 agatggcaag tgagcggcta ggtgtgggct ttggtgttgt ggatctgtcg ctagctccca
    11641 ctccagcagt tggtgactct gtggcacgtg tcttagagga gatgggactt gaaatagttg
    11701 gcacacatgg cacgacagct gccctagctt tacttaatga cgcagtcaaa aagggtggtg
    11761 tcatggcttg caaccgagtg ggtgggttgt caggtgcctt tatccctgta tcagaggacg
    11821 agggcatgat tgcagcagtg cagggaggct cgcttaatct tgaaaagcta gaagccatga
    11881 ctgccatttg ctcggttggt ttggatatga ttgcgatccc agaggagaca ccgtctgaaa
    11941 ccattgcagc catgattgct gatgaggcag ctatcggggt gattaatcaa aagacaacag
    12001 ctgttcgtat tattccaaag ggtaaggagg gtgatatgat tgcttttggt ggtcttttag
    12061 ggacagctcc ggttatggct gttaatccgc attcatcggc tgactttatt gctcgtggtg
    12121 ggcagatacc agctcctatc catagcttta agaattaacg gctagcactt gcatggtttt
    12181 gcaagtgttt tcttttaatg ctataatagc agagagactt tggaggttca ttatgacaaa
    12241 aacaagatta tacattgtca gacatggcaa gacgatgttc aacaccattg gtcgtgcaca
    12301 gggttggagt gataccccct tgacaaaggc aggagaagaa gggattcgtg aattgggact
    12361 tggtttgaag gctgctggta ttccattcaa ggctgctttt tcgagtgatt caggtcgtac
    12421 catgcagaca atggagatta ttctacgaaa gtctgaaaat gagtttttac cctacactag
    12481 agataagcgg attcgtgagt ggtgctttgg tagtctagat ggggcttatg attccgagct
    12541 gtttttaggt gttttaccta gaacaaaggc ctttgaaaat cgtgacaatc tgcgtgatgt
    12601 gccttattca gaattagcag agagtattgt cgaggttgat actgctaact gggcagagcc
    12661 ctgggaggta ttgagcaagc gtatctatga gggctttgag gctatcgcgc ttgctgttga
    12721 aaatgcagga ggtggcaatg ctatcgtggt tagtcatggc atgaccattg gaacctttat
    12781 gtggctaatt gacccagata gggaaaagca atacattgac aatggaagcg tcactgttgt
    12841 ggaatatgag aatgggcagt ttaccatcaa aacgattgga gatatgagct accgctatcg
    12901 tggtcgtgag ataattgagt caataagaga tgaagaataa cactataaga gtccttttac
    12961 aggccttggt cgtcctgttg tttttatcag gggtttacct ctttatcaag cctgaaaaac
    13021 aggctgtagg ccccaaggct aatcaaacag tacctgcccc aaaggcagct aagcaggcta
    13081 aaaagactac tgatctgcca aaggtatcaa ctacggactg gcagctggtc cttgtcaatc
    13141 gcgatcaccc tcaagaggaa atgagtcctg agttggttga gattaatggg attcctattg
    13201 ataagcgcat tgagcaggag acggctgatt ttctagcagc ggcgcagacg attgaacctc
    13261 aggagcactt gattgctggt tatcgttcgg ttgtccagca agaagagctt tatcagtctt
    13321 atattgccca agagctggca aatgatccta gcctgaccca agaggcagct gaagccttgg
    13381 ttcggaaata tgcccagcca gcaggcacta gtgaacatca gactggtcta gccattgata
    13441 tgagcacagt agataactta aacgctagtg atcctaaggt ggcacaggag attcaaaaaa
    13501 tagctccaca atttggtttt attttgcgct atccaaaagg gaagcagact agcacaggga
    13561 ttgagtatga ggactggcat tatcgctatg ttggtaaagc ctctgcccta tacattaccg
    13621 ctcatagcct cagcctagaa gaatacctaa cacgattgaa ggagaaaaaa tgagaaaacg
    13681 acttaaattt tcctattttc tagtgttttt agtgttcatt atggtggctt tgattggtcc
    13741 cttgctgttc aatgccaaag gcacatcggc cagtcaggag atgtctgttc cctatacaga
    13801 gaggcaattt atccagttgg ttgctaagga ggtcaagcca ttggccaaaa actatggcat
    13861 tcgtccttct attttgattg gtcagattat tttagaaacc aattatggca gaaccctgtt
    13921 ggcggccaaa taccacaacc ttttttcact gcagccagct ccagggcagg cttccattag
    13981 cctcaagaag caagcagcct caaagcacaa gacagcctat gctatctatc gggacagaga
    14041 ggactctatc agagcttact tatcatggct tagtcaaggc acaggcgagg agaaaaagct
    14101 ttaccaaagc ctagcaaccg aaaaagggta taaaaaacct gctaaaagtc tgcagaccta
    14161 tcgctattct gatgataagg gctatgccca aaggcttgtg cagctgattg aagcaagagg
    14221 tttgacaagc tatgatgatt gaggagatga aaaagacacc gaaacaaccg gtaagctcag
    14281 gtatttgctt tagtaggtat tgcaactttc tatcagcttg aaggtgtaag ccttaagagt
    14341 aggagctgtg agcacgcagc ctgatttatc ctgctctact aaaggcttga ttgttaggcc
    14401 ttaaggcttc aggcagttaa gctaatcccc cttacagctt agcgctcctt ttagctagcg
    14461 agtcgggaga agccaatacc agtctgagag gtagtaagtg gctctctatt acttctttca
    14521 agcataatgt caaaggcaac actgtcaatg ttttataaaa attagcactc taaaaaaaga
    14581 gtgctaattt tttgagtttt tttcttgaca tgctagttta aaaggatata atagaattat
    14641 aaattagcag tccgatgtat agagtgctaa cagaaaggga gtgattggtt tgtgatcaca
    14701 gagagacaat ctaatatttt gaatcttatt gtagatttat ttacacagac ccatgaacca
    14761 gttggctcta aggctttgca gtcacttatt gcttctagta gtgccactat tagaaatgac
    14821 atggcaaagc ttgaaaaact aggattgctg gagaaggctc acacatcaag tgggcgcatg
    14881 ccaagtgcgg caggctttaa atattttgta gagcattctc ttaatcttgg cagcattgat
    14941 gagcaggacc tttatcagct ggtcaaggcc tttgattttg aggcctttaa gctggaggac
    15001 gttttgctaa gagccagcca gatgctatcg gatacgaccg gctatacggc ggcgatttta
    15061 gatgttgagc ctgcaaggca aaggctgaca ggctttgata ttgttcagct atctagtcat
    15121 gatgccttgg cagttttgag cttagatgag tccaagccgt tgaccgtaca gtttgccatt
    15181 cctaagaatt ttatgaatcg tgatttgctg gtgcttaagg gcattgttgc tgatcgctta
    15241 cttggcaaag atgttatgac tgttcattac aagctgcgaa ccgaaatccc tcagattgtt
    15301 cagaagtatt ttacggtgac agacaatgtt ttggatttgt ttgattatat ctttgtcggg
    15361 ctttttcgag aaacgatttt tgtctctggc aaggttgctg cccttgacta tgctggtctt
    15421 gcgacctatc agtttcttga tgaggagcag cgcttagccc tatctatcag acagagtcta
    15481 tcagaggaag agatggcaac ggttcaggtt gctgacagca gtgagccagc cctagcaaac
    15541 gtgaccttgc tgacctacaa gtttttaatt ccatacagag gatttggcct cttaagctta
    15601 attgggccag ttgatatgga ttatcgtcgt agtgttagct tgattaatgt gattggtcag
    15661 ctactggctg tgaagctaag agattattac cgttacttaa acagcaacca ttatgaggtt
    15721 cactaaggcc ttaatatgat ttaagaaaat gtaagaaagg ggtagacacc ttgtctaaaa
    15781 aaccaaaaga agagctcaag gatcaagagg acattcttga tgaggctgct gaggaagcag
    15841 tagagccagt tgaagaagct gatcaatcag ctgagcttat tgctgatgaa gcagccgagg
    15901 aaccatctga gctagagttg gctctccagc gagcagaaga ttttgaaaat aaatacctca
    15961 gagctcacgc agaaatgcaa aatattcagc gtcgtgcgaa tgaagaacgc caaagcttgc
    16021 agcgctatcg ttcacaggat ttagctaaaa aaatccttcc aagcttagat aacttggagc
    16081 gtgctttggc tgttgagggt ctgacagatg atgtcaaaaa aggcctagaa atggtgcaag
    16141 aaagccttgt tcaagccctt aaagaagaag gtattgaaga ggttcctgtg gaagcctttg
    16201 accacaatct gcacatggca gtccaaaccc taccagcaga tgatgaccac ccagcagata
    16261 gtatcgctca ggttttccaa aaaggctata agcttcatga gcgcttacta agaccagcga
    16321 tggtggttgt gtacaactag tcactaatga tggccattga aatggctcgt cattagacgg
    16381 caaccgctgt ggcggcttgc ctagactcct tactagctcg atagcaaaat ggtatcgatt
    16441 ttgctatctc acgtcgcaat tatcccgtga tgatagctaa tcaataaaat gaatcatgtc
    16501 cgaaatgacg gtaaactatg aaaataagaa ataagattgc tgctttttgc gctagcaaaa
    16561 gcgaacgaag tgagcattac cgatactctt cgccgtggca aaagtcataa aacactagtg
    16621 ttttatgact cggaaaattt gagactttag gctcaaattt cagctatgag attccatagg
    16681 aagctgctag cgtccgtgcc acataagagg agtatcataa atatataaaa gaggaaaaaa
    16741 tattatgtct aaaattatcg gtattgactt aggaacaaca aactcagcag tagcagttct
    16801 tgaaggaaca gaaagcaaaa tcattgccaa cccagaaggc aaccgcacaa ccccttcagt
    16861 agtgtcattt aaaaacggtg aaatcattgt cggtgacgct gccaagcgtc aagcagtgac
    16921 aaaccctgac actgttatct caatcaaatc aaagatggga acctctgaaa aggttgctgc
    16981 taatggtaaa gaatacacac cacaagaaat ctcagcaatg attcttcaat accttaaagg
    17041 ctatgcagag gactaccttg gtgaaaaggt aacaaaggct gttatcacag ttcctgccta
    17101 cttcaacgat gcacaacgtc aagctactaa ggacgcaggt aagattgctg ggcttgaggt
    17161 agaacgtatc gtcaacgaac caactgcagc agctcttgct tacggtcttg acaagacaga
    17221 taaagaagaa aagatcttag tctttgacct tggtggtggt acctttgacg tgtctatcct
    17281 tgaattgggt gatggtgtct ttgatgtgct tgcaactgct ggtgacaaca agctcggtgg
    17341 tgacgacttt gaccaaaaaa tcattgattt cttagtagca gaattcaaga aagaaaacgg
    17401 tattgaccta tcacaagata aaatggctct tcaacgcttg aaggacgctg ctgaaaaagc
    17461 taaaaaagac ctttcaggtg tcactcaaac tcaaatttca ttgccattca tcactgctgg
    17521 cgctgctggt ccgcttcact tagagatgag cctgtctcgt gcaaaatttg atgacctgac
    17581 tcgtgattta gtagagcgta cgaaggttcc tgttcgccaa gcgctgtctg atgcaggctt
    17641 gagcttgtca gaaatcgatg aggttatcct tgttggtggt tcaactcgta tcccagctgt
    17701 ggttgaagct gttaaggctg aaactggcaa agagccaaac aaatcagtga accctgatga
    17761 agttgtagcg atgggtgctg ctatccaagg tggtgtgatc actggtgatg ttaaagacgt
    17821 tgttcttctt gacgtgacac cattgtcact tggtatcgaa acaatgggtg gcgtctttac
    17881 aaagcttatt gaccgcaaca caacaattcc aacctctaaa tcacaggtct tctcaactgc
    17941 agcagacaac cagccagctg ttgatatcca cgtgcttcag ggtgaacgcc caatggcagc
    18001 agataacaaa acacttggac gcttccaatt gacagacatt cctgcagccc ctcgtggtat
    18061 cccacaaatc gaagtaacct ttgacatcga caaaaacggt attgtttctg ttaaggcaaa
    18121 agacctaggt actcaaaaag aacaacatat tgtcatcaaa tctaacgatg gtctttctga
    18181 agaagaaatt gaacgcatga tgaaagacgc tgaagccaat gctgaagccg atgcaaaacg
    18241 taaggaagag gttgacctta aaaatgaagt tgaccaggct atctttgcaa ctgaaaagac
    18301 tattaaagaa actgaaggca aaggctttga cacagagcgt gatgctgctc aaacagctct
    18361 tgatgagctt aagaaggctc aagagtcagg cgaccttgat gatatgaaag ctaagcttga
    18421 agcgcttaat gaaaaagcac aagcccttgc tgttaaaatg tacgagcaag cagccgcagc
    18481 acaacaagcc caggctggtg cagaaggtgc agcagataca ggctcaacaa acagtggcga
    18541 tgatgttgta gatggtgagt tcactgaaaa ataagctgtg aggagctaag gtcgctcagt
    18601 aaagctagaa actgaggcga tagtcccctc ccctaattgc tagaaaatag catagcaagg
    18661 ctaaataaat aaaaatcaaa taggcggggc gcctcgctcc gtctgttttt gtcaatgaag
    18721 gaaagaataa atgaataata cggaatacta tgatcgtctt ggggtctcaa aggacgcttc
    18781 ggccgatgat attaaacgag cttaccgtaa gatgtctaag aaataccacc cagacatcaa
    18841 taaagagccg ggagctgagc aaaaatataa ggacgtacag gaagcctatg aaaccctaag
    18901 cgattcacaa aagcgtgcag cctatgatca atacggggca gccggagcaa acggtggctt
    18961 tggtggtggc gcaggcggtt ttggcggctt cgatggtggt ggctttggcg gctttgagga
    19021 tattttctca agcttttttg gcggtggtgg tatgcgtaat cccaatgctc cacgtcaggg
    19081 cgatgacctt caatataggg taaacctttc ttttgaggaa gctgtttttg gtaccgaaaa
    19141 agaggtcagc tatcatcgtg aatcaacctg tagcacctgt gcaggctcag gagctaagcc
    19201 tggaacaagt cctacaacct gccgtaaatg tcatggctca ggggttatca atgttgatac
    19261 gcagacccca cttggcatga tgcgtcgtca ggtgacctgt gatgtctgtc atggcagcgg
    19321 tcaagaaatc aaagagcctt gccatacctg tcatggaact ggtcatgaaa agaaggttca
    19381 taaggtttca gtaaaaatcc cagcaggtgt tgaaaccggc caacaaatcc gcctacaggg
    19441 tcagggggaa gcaggcttta atggtggacc ttatggtgat ttgttcgtta ttttaaacgt
    19501 gcttccaagt aaacagtttg agcgcaatgg ctctactatt tactacagct tgaatatttc
    19561 atttgttcag gctgctttgg gagatacagt agatatccca acggtccatg gtgatgttgc
    19621 catgtctatt cccgctggaa cacaaactgg taaggtattt cgcttgaagg gcaagggggc
    19681 tcctaagctt cgaggcggag gccaaggaga ccagcatgta actgtaaaca ttgtaacgcc
    19741 taccaagctc aatgaggctc aaaaggaggc cttgaaggct tttgcggagg ctagtggcga
    19801 aaagccgatt gctccaaaga aaaaaggttt ctttgacaag gtcaaagacg ctctagagga
    19861 tatttaagcg ggtcttgttt acacactcta tgagcgattg atcacaattg tatagaatgg
    19921 ttgagcatag cacatgccaa agtttcagag tctaggacac ttttgtctta ggctctttta
    19981 ttagaggtat agaggctagg tctgagcttg gttttagggc tgcatgcttt aaattgcgca
    20041 gtcaatttta atgtattttt tacaatcttt ttcttgcata acgactgatt ctagtgtact
    20101 atagtctagt aattaatttg attgtcaaat tatttggtca taaaattatt tggtaatcaa
    20161 ataagctgtc agaaaagagg agtgatatga cgtttcaaaa tatcattttt gagcttgaag
    20221 aggatctggc cattttaacc ttaaatcgtc cagaggtgtc taatggcttt aacattccag
    20281 cctgtcagga gattctggag gctattaggt tggttaagga taacccctct ctgcgctttt
    20341 tagtgattaa ggcaaagggc aaggtctttt cagtcggtgg tgacttggtt gagatgcaaa
    20401 atgctgttga aagagatgat gttcagtctc tagttaggat tgctgagctg gttcaggata
    20461 tttcctttgc tatcaagcaa ttgccaaagc cggttatcct ctgtgctgat ggtgcggtgg
    20521 ctggtgcggc ctttaatatt gccttagcgg tggatttttg tattgctagc acccagacaa
    20581 aatttattca ggcctttgtt aatgtcggct tagcgccaga tgctggtggt cttttcttgt
    20641 taacacgtgc cgttggtcta aatagagcga ctcatctggt gatgaccggt gagggggtca
    20701 cagcagaaaa agggcttgag tacggatttg tctatcgagc tgctgagtca gataagcttg
    20761 ataagacctg tagtcagctg ttaaagcgtt tgaggcgtgg ctcttcaaat tcctacgccg
    20821 gcatgaaatc tttggtatgg caaagctttt ttgcaggttg ggaggattat gcccaaaaag
    20881 agcttgctat tcaagaggaa ttggccttta aggaggactt taaagagggc gtcagggctt
    20941 atggagatag gaggcggcca aattttcggg ggaaatagct cttatgtgct tgcaaaatac
    21001 tttgatgtct gatatacttt gatagtcaaa gtattttaca gctagggagg tgtttacttg
    21061 gaatataata agattaatca atatttagtt gatattttca acagaatttt ggttattgag
    21121 gaaatgagct taaaaacaag tcaatttaat gatgtttctc taaaggagat gcacacaatt
    21181 gagattattg gaaaatatca gcaggtaacg ccaagtgaca tcgcaagaga gctcatggtt
    21241 accttaggaa cggttaccac tagcttaaac aagctagagc taaagggcta tattgaaaga
    21301 acaagatcaa gcgtggatag acgggttgtt tacctgtcac tgaccaaaaa ggggcgtctt
    21361 ctggatcgtc tccatgcaag attccataaa aatatggtcg gtcatgtgat cgctgatatg
    21421 aatgaggacg aaatgcaagc cctgttacgt ggcttgggga acttacatca gtttttggag
    21481 gatttggttt aatggtcttt tcaaaaatta gtcaggtagc tcattatacg cctaagcagg
    21541 ttattagtaa tgacgatctg tcgcaaatca tggacaccag ccacgaatgg atttcgtcac
    21601 ggactgggat tgagaagcgt cacatttcca ctgtggagat gaccagtgat ttagccattc
    21661 gggtagcaga gcaattgtta gcagggtcag gatatgatgc gactgcactt gattttatca
    21721 tcgttgctac gattagccca gatgctagca tgccatcgac ggcagcaaag gttcaggctg
    21781 ctatcggtgc tactaatgca tttgcttttg atatgacagc ggcctgcagt ggctttgtct
    21841 ttgccttagc aatggcggat aagttgattg catcaggggc ttatcaaaga ggcttggtta
    21901 ttggagcaga gaccctgtct aagattattg attggcagga tagaagcaca gctgttttat
    21961 ttggagatgg tgctggtggg gttttattag aggccagcga gcagcagcat tttctagctg
    22021 aggccttaca tactgatggt gcgcaaggtc aaagcctgac atcaggtcag agcagtctgc
    22081 gctcaccatt ttctcaagga caggaggtca actcctttct tcagatggat ggtcgtgcta
    22141 tctttgactt tgcgattaga gatgtttcaa ggagcattac agcaattatt gagcaatcag
    22201 gcttggccaa ggaggagtta gactatctgc ttttacatca ggccaatcgg cgtattttag
    22261 ataagatggc taagaaaatt ggtatgccaa gagagaaatt tctggaaaat atgatgcact
    22321 atggcaatac cagtgcagct agtataccga ttttgctatc tgaatcagtc caaaatggac
    22381 agcttaaatt agacggcagc cagcatattt tactgtcggg cttcggtgga ggtttgacat
    22441 ggggcagtct aattgttaaa atctagttat atcatgtgcc tagcacattt ataaaataaa
    22501 tatttatatt aaggagacat aaaatggcag tatttgaaaa agtacaggaa attatcgttg
    22561 aggagcttgg caaggacgca gaggaagtaa ccttagaaac tacctttgat gatttagatg
    22621 ctgactcact tgatgttttc caagtgatct cagaaattga agatgccttt gacattcaaa
    22681 tcgaaacaga agaaggctta aacacagttg gtgaccttgt tgcctacgtt gaagaaaaaa
    22741 caaaataaag ctcaaacaag cgagaatact gattaaccag cctgctgatt aatgaactgc
    22801 tttagttggt caattgatat gtaataatcg aaccatcagg gtgagattag accctctttc
    22861 aggctctaac tcgctctttc ttcttattat gatagtttga ttatcaaatt attctcctga
    22921 tttctttgca tagaaggtta ttatgaaaac acgtattaca gaattactta atattgatta
    22981 tcccattttt cagggaggta tggcctgggt ggctgatggt gatctagcag gtgctgtctc
    23041 caatgctggt ggtcttggga tcattggtgg aggaaacgct cctaaagagg tggtcaaggc
    23101 aaatattgat cgtgtcaaag cgatcacaga taagcccttt ggggttaata tcatgctgct
    23161 atctcccttt gcagatgaca ttgtcgattt ggtgatcgaa gaaggtgtca aggtggtgac
    23221 cactggcgct ggaaatccag ggaaatacat ggagcgcctt catgaggcag gtattatcgt
    23281 gattccagtt gttcctagcg ttgccctggc taagcgcatg gaaaaattag gcgttgatgc
    23341 tgttattgct gaaggaatgg aggctggtgg ccatatcggt aaattgacaa cgatgacctt
    23401 ggttaggcag gtggtagatg ctgtttctat tccagttatt gcagcaggtg ggattgcaga
    23461 tggtcgaggt gcagcagcag cctttatgct gggtgctgag gctgttcagg ttggaactcg
    23521 atttgttgtg gcaaaggaat ctaatgctca ccaaagcttt aaggataaaa ttttgaaggc
    23581 taaggacatt gatactgtca tttcagctca agttgttggt catccggtac gctctatcaa
    23641 aaataagcta acatcagctt atgctaaggc tgaaaaagaa tttttagcag atcgtaaggc
    23701 tgctagtgac atcgaagaaa tgggagcagg agctctgcgc aacgctgtga ttgatggtga
    23761 tgtgatcaat ggctctgtca tggcagggca gattgcaggc ttaattagag cagaagaaag
    23821 ctgtgaagcc atcctaaagg atatctacta tggtgcagca gcagtgatta gtcaagaagc
    23881 taagcgctgg caagctcttg cagctgatga caaaaacgaa acgatataaa taaggagaag
    23941 tatgacaaaa acagcctttt tatttgctgg tcagggtgct cagacactag gcatgacaag
    24001 agatttgtat gaccaatatg ccattgctcg tgacaccttt gatcaggcta gtcagctttt
    24061 aggctatgat ttacgcaagc tcattgatac cgaccaggat cggttgaacc agacagccta
    24121 cacgcagcca gcaatcttaa ccgcttcagt ctccatttat cgtatcttaa cctcttatgg
    24181 ggttcatcct gatatggtgg cggggctttc tcttggagaa tattctgctc tagttgcggc
    24241 aggtgttctg agttttgaga ctgccctaga gctagttgca aaaaggggac gctttatgga
    24301 ggaggcagcg cctgctggct ctggtaagat ggtagctgtg atgaatacag aggctaggct
    24361 tattgaggag gcttgtcaag aggcttcttc ggttggtgtt gtgtcacctg ctaactataa
    24421 tacgccagga cagattgtta ttggtgggac agctgaggct gtcaatgcgg cacttgaaat
    24481 cttaaaagca aagggagtga agcgtttaat tccgctgaat gtctcaggac ctttccatac
    24541 agcactttta gcgcctgcta gtcaaaggtt ggcagaggag ctcagcaaga ttcaatttca
    24601 ggactttgat ctgccactgg ttggaaatac agaggctaag gtcatggaaa aggatcggat
    24661 tgcagaatta ttggcgcgtc aggtcatgga gcctgttcgt ttttatgata gtatcgaggt
    24721 tatgaaggct aacggtatca cccagtttgt tgagattggc cctggcaggg ttttaacagg
    24781 ctttattaaa aaaatcgaca aaaagctgct atgcagcagt gttgaagata tgccaagcct
    24841 acaattgtat ttgggaaaat aggagggaat gctaagctat ggaaattaaa ggaaaaaacg
    24901 tttttatcac agggtcaaca agaggcattg gactagcaat ggctcatcaa tttgcaggac
    24961 taggcgccaa catcgttctc aatggtcgct cagcgatttc tgatgagctg gtggagacct
    25021 ttaaggatta cggtgtgaag gttgtgccga tctcaggaga tgtttcagag ggggctgatg
    25081 ctaagcgaat ggttgatgag gctattgagc agcttggctc tgtggacatt ttgattaaca
    25141 atgctggcat cactaatgat aaattaatgc ttaagatgtc agaggaggac tttgagcgtg
    25201 ttctcaaaat caatctgaca ggagcattta acatgacaca atcggtctta aagccgatga
    25261 caaaggctcg tcagggtgct atcatcaatg tgtctagtgt tgtcggccta acaggaaata
    25321 tcggtcaagc aaattatgca gcgtccaagg caggcttgat tggctttacc aagtcagttg
    25381 ctcgtgaggt tgcggcgcgt ggcattcggg taaatgcgat tgcaccgggc ttcatcgaat
    25441 ctgatatgac aggtgtcctt tctgaaaaga tgcaagagca aatcttaaat caaatcccaa
    25501 tgaagcgtat tggcaagggg caagaggttg ctcaggcagc aagcttccta gctagtcagg
    25561 attatattac tggtcaggtg cttgccattg acggcggcat gacaatgcaa taaaatagag
    25621 gtattaaaat gacattaaac agagtagttg taacaggtta tggcgtgact tccccaattg
    25681 ggcatactcc agaggagttt tggtcaagct taaaggcagg tcatattggt attaagccta
    25741 tcacaaaatt tgatacgagt gacttcgctg ttaagaatgc agcagagatt caggattttc
    25801 catttgataa gtattttgtc aaaaaggatc taaatcgctt tgacatgtat tccttgtatg
    25861 ccttatatgc tgcgacagag gcgattgaac atgctggcct agatattgaa gcgattgatt
    25921 ctgaccgctt tggtgttatt gtagcgtctg gtattggagg cattcaagag attgaagagc
    25981 aggtgattcg gttacatgaa aaaggaccaa agcgcgttaa gccgatgact ctaccaaagg
    26041 ccttgccaaa tatggcggct ggtaatgttg ccatgaagct gaatgcccaa ggcgtatgta
    26101 agtcaatcaa tacagcctgt gcctcttcaa acgatgctat tggcgatgcc tttcgtacaa
    26161 ttaagtttgg tcttcaagac gtgatgatgg ttggaggatc agaggcagcc attacaaaat
    26221 ttgccattgc gggcttccag agcttgactg ccttgtcaac aactgaggac ccaagccgca
    26281 gctctattcc atttgataag gatcgaaacg gttttatcat gggtgaagga tcaggtatgc
    26341 ttgttttgga aagcttagag catgctcaaa agcgcggtgc gactatttta gctgagattg
    26401 ttggctacgg caatacctgt gacgcttacc acatgacctc accacaccca gaaggacttg
    26461 gtgctcgtaa ggccattaat ctagcattgc aggaggccgg tattgatgca gcagctattg
    26521 actacgtgaa tgctcatggc acctcaactc ctgctaatga aaaaggagaa agtcaggcta
    26581 ttgttgcagt gcttggtaaa gaggttcctg tctcatcaac caagtccttt acaggccacc
    26641 tactaggggc agctggtgct gtggaagcta ttgcaaccat agaagcaata cgtcacaatt
    26701 atgttccaat gacagctggg acaaaggagc tgtcagatga tattgaagca aatgttattt
    26761 ttggccaagg aaaagaagcc gatattcgtt atgccatgtc aaataccttt ggctttggag
    26821 gtcataacgc tgtattagcc tttaagcgtt gggaggatta aaatgaatat tcaagagata
    26881 aaggatttga tggcacagtt tgatgcgtca agcctacgcg aattttcatt caaatcaagt
    26941 gatggggagc tgttatttag taaaaatgag caccgtccga tggcagctcc agctcctgag
    27001 cctgttactt tgcaccagga ggtagcccct attagcctga cgcaggagat tgtctctaaa
    27061 caggaatcaa tccctgcttc ttcaggtctg caagagccag aaggagaagt agttgacagt
    27121 cctcttgttg gtgtggccta tcttgctgcc ggtcctgaca agcctccatt tgttactgtt
    27181 ggtgatagcg ttaaaaaggg acagacattg ttaattgttg aggcgatgaa ggtcatgaac
    27241 gagattcctg ctccttgcga cggtatcgtg acagagattt tagtggccaa tgaggacgtg
    27301 gttgagtttg gacaaggatt ggtacgcatt aaatgatgga tataaaacag attcaagagg
    27361 cattgccaca tcgctaccca atgctgcttg ttgatagaat tttagaggct tcagacgatg
    27421 aaattgttgc catcaaaaat gtcactatca atgagccctt ctttaacggt cattttcctc
    27481 agtatccagt catgccaggt gttttgatca tggaggcctt ggcacaaact gctggcgtct
    27541 tggagctatc aaaagaggaa aataaaggca agcttgtttt ttacgctggt atggacaagg
    27601 taaaatttaa aaagcaggtg gttccgggag accagctagt catgacagct aggtttatta
    27661 agcgtcgtgg gacaatagca gttgttgagg ccaaggcaga ggttgatggc aaattagcag
    27721 ctagtgggac cttgaccttt gcttttgggc agtaaaagac taatcgtctg tggaggaaaa
    27781 aagaacctat gtttaacaaa atcttaattg ccaatcgtgg tgaaatagca gtgcggatta
    27841 ttcgtgcagc acgagaatta ggcatttcca cagttgctgt ttattctgag gctgatagag
    27901 aggctttaca tacgatcttg gcagaccaag ccatctgtat tggaccgtca agatcaaagg
    27961 aatcctatct caatatgaat tctgtcttat cagcagctgt ggtgacaggg gcgcaggcta
    28021 tccacccagg gtttggtttt ttaagtgaaa attcaaaatt tgtgaccatg tgcgaggaaa
    28081 tgaacatcaa gtttattggc ccctcaggag ctgtcatgga taaaatgggc gacaaaatca
    28141 acgcccgcgc tgagatgatt aaggcaggtg ttcctgttat tccaggctca gacggcgagg
    28201 tttacaatgc ccaagaggct cttgagattg caaggcagat tggctatcca gtaatgctaa
    28261 aggctgctgc aggcggtggc ggcaagggaa tccgaaaggt tgaatccgag gctgatttag
    28321 aggctgcttt taacgctgct agtcaagaag ctttaggagc ctttggtaat ggtgccatgt
    28381 atttggagaa ggttatttat ccggcaaggc atattgaggt gcaaatttta ggtgattcac
    28441 aggggcatgt gatacacctt ggagagagag attgctcctt acagcgtaac aatcaaaagg
    28501 tactggagga aagcccttcg attgcgattg gcacaacact gcgtcaaagg atgggtgaag
    28561 ctgctgttcg tgctgccaag gcggtgtcct atgagaatgc tggcacaatt gagttcttat
    28621 tagatgaagc cagcggtgat ttttacttta tggagatgaa tacgcgtgtt caggtagagc
    28681 accccgtaac agagtttgtt acaggcgttg acattgtcaa ggagcaattg cggatcgcag
    28741 caggtcttcc tttatcagtt cgtcaagagg atattgtgat tactggccat gctattgagt
    28801 gtcgtattaa cgcagaaaat ccaagcttta attttgcacc aagccctggt aagattacag
    28861 atctttacct accaagcgga ggtgttgggc ttaggattga ttctgctgtt tacagtggtt
    28921 atacgatacc gccttattat gatagtatga ttgctaagat tatcgttcat ggagataacc
    28981 gatttgatgc tttgatgaag atgcaaaggg ctctgtttga gttagagatt gaaggtatta
    29041 tgaccaatat tgattttcag atggacttga tttcagacaa gcaagtgatt gcgggtgatt
    29101 acgatacgtc gtttttgatg gaaacctttt tacccagcta caataaagat taggagtaga
    29161 tatggcctta tttagtaaaa aagacaaata tatccgtatt actcccaata attctctcaa
    29221 aagctctgtc agtcgtaatg ttccagaggt gccagacgaa ttatttgcca agtgtcctgc
    29281 ctgtaagcac atgatttatc aaaaggatct ggggccggca aagatttgtc cgacctgctc
    29341 ctataatttt aggatttctg ctcaggagcg cttgacttta accgttgatg aaggctcttt
    29401 tcaggaattg tttacagata ttgaaaccaa ggatccatta agatttccag actaccaagc
    29461 caagctgcaa aaggccaggc aggctactgg cttgcatgag gctgtcctga ctggaacagc
    29521 tctggtcaag ggacaaaggc ttgctctagc catcatggat tcgcatttta tcatggcaag
    29581 catggggacc gttgttggtg agaaaatcac tcgcttattt gagctggcta ttagtgagcg
    29641 gctcccagtt gttattttta cagcgtctgg tggagcccgt atgcaagagg gcattatgag
    29701 tctgatgcag atggctaagg tttctgcagc tataaagaaa cattcaaatg ctgggctttt
    29761 ttacctgact atcctaactg atccgaccac aggtggtgtg acagcgagct ttgcaatgga
    29821 gggtgatatg attattgcag agccccagtc cttggttggt tttgctggtc gacgcgtcat
    29881 tgagacgaca gttagagaaa atttaccaga tgattttcaa aaggcagagt tcttaaaaga
    29941 gcatggcttt gttgacgcta ttgtgaagcg gactgacctg cgtgatcgga ttgctcattt
    30001 ggtggcattt catggaggtg tatcatgaca gacgtcgcaa gaatattaaa ggaagcgcgt
    30061 gaccagggtc gaatgacagc tctagattat gccagcctga tttttgatga gtttatggag
    30121 ttgcatgggg atcgtcagtt tgctgatgat ggctctattg ttggtgggat tgcctatttg
    30181 gctgatcaac cggtcacagt gattggtatt caaaaaggaa aaaatcttca agataatctg
    30241 gctagaaatt ttgggcagcc gcaccctgag ggctatcgta aggccttacg cttaatgaag
    30301 caggctgaaa aatttggtcg tccagtgatt acctttatca atacagcagg agcttatccg
    30361 ggcgtaggtg ctgaggagcg cggtcaaggt gaagctattg ctagaaactt gatggaaatg
    30421 agtgacctca aggttcctat cattgctatt attattggcg aaggcggctc aggcggtgct
    30481 ttagctttag ctgttgctga tcaggtttgg atgctggaaa acaccatgta cgctgttctt
    30541 agcccagaag gctttgcctc tattctctgg aaggatggct ctagggctac tgaagctgct
    30601 gagctcatga aaattaccgc agctgagctg tatcaaatgg gcgtcattga tcggattatt
    30661 ccggagcggg gttatttttc gagtgagatt gttgagatga taaaatcaca cttaattgac
    30721 gaaatcactc agctacaggc caagccctta gaggaattat tggatcagcg ctaccagcgc
    30781 tttagaaaat attaaggaca tcaaaaaaga cctctgtaag gctagcagtt agctaggagt
    30841 tacagaggtc ttctttattg ttaggatcaa tctcattaat cggctctttg tccccctaca
    30901 attgataaag agcctttttt gtacatagaa aaaagcccta tcatttctac tgtgtcctta
    30961 tctactacag aaatgataga gcccattaat cgtcttgttg gcaccttatc cggccagtct
    31021 ttggctttaa cgtggcttga tcacctctag tccacccata taaggacgaa gcacttctgg
    31081 aatcgtcact gagccgtcct cattttggta attttctagg atagcagcta cggtacgtcc
    31141 gacagcaagc ccagagccat ttagggtgtg cagtagctta accttgccat ctgcctcatc
    31201 gcggtagcga atttgtgcgc ggcgtgcttg gaaatcttcg gtatttgagc agcttgagat
    31261 ttcgcgatag gtgttttgag cagggatcca aacctctaaa tcataggttt tagcggccga
    31321 aaagcccata tccccagtac aaagagccaa gacacgataa gggagcttta gcttttggag
    31381 aatatgctcg gcattggcgg tcattttttc cagctcttca taagatgttt cgggcttagc
    31441 aaacttaacc atttcgacct tatggaattg gtgtaagcga atcaagccac gagtgtcgcg
    31501 gccagcagag ccagcctcag agcgaaatga tgggctcatt gcagtaaagt agattggcag
    31561 ctccttacca tctatgatgt caccacgata gtaattggtt aatgggactt cagcagttgg
    31621 gataagaaca aagtttgtcc catctagctc aaaggtatcc tccttgaatt ttggatattg
    31681 accagtgcca aacatagagt catgattaac catataagga ggaatgattt cttgatagcc
    31741 ctcttttagg tgctcatcaa gcatgaagtt ataaagggca cgctccagcc ttgcaccaag
    31801 atttttatag aataagaagc gagcaccggt aacctttgcg ccacgctccc aatcaaggat
    31861 atctaaggct tctccaagat cccaatgcgc cttgatgtca aaatcaaact gacgtggctt
    31921 tccccagcga tgaatctcta cattgtcctc ttcatcagct ccaataggaa ctgaatcatg
    31981 gggagtattt ggcaaaacag tgatgatacc ggtaatttct tggtcaatgt cagctagctt
    32041 agcatcaatt gccttgatgt tagcagctag ctgctgcatg tcagcaatct gttggctggc
    32101 gtcttccttt tggcgtttgg cttgagcgat agcagcagag gcgatattac gctgggcttt
    32161 tagctcttct gtttgaacaa gcagggtgcg ccgctgttca tctaaggctt ttagagaggt
    32221 taggatagct tctgacacac cacgtgtttt gagcttagca gcaacagtat caaaatcagt
    32281 acgaatacgc ttaagatcta gcataaataa atctcctttg agctggtgat aagatagtca
    32341 gttataaaat agcatgagca aagctagctg atcgcttttt tatttctgac gagataaaaa
    32401 agcacagcct atgaatacac tggagcgcct aagcgcggtt ccatccagct tcacaatctg
    32461 tgcacttaat tcatatttaa ttggtagacg gtagaatttc gtatgactcc tctatctgtt
    32521 ttcagcaacc acagactctc tgaaagacag agccagacta cttatccgct agacctatta
    32581 taacaaaaaa ggagaaaaag taaactccca aatgagtgtc agctacatca aacgcgcgaa
    32641 ctagttattt tggaattaga gtagacactt tcaatgtttt tcctatagta aagtctataa
    32701 aaaacaagac atatccttga aatacagaaa gctttctttt cttgctaaaa ctttttcatg
    32761 tgtctgtcac ggagcgtcag taatacaaaa ggctgatgac aagtagagct taggtcagag
    32821 gcacaaaaaa tctcgttgtc agacaaaatc aaatcgttaa atattaaaaa ttgtggtaaa
    32881 ctaatattat gcgtaaaaat gtaatgacat tagataagaa ccgccattac ggtttagatt
    32941 tattgcgaat catttccatg tttatgattg tgatcacaca tgttttggga aagggcggct
    33001 tgcggtcaac tgtcgaaggt gaggcagatt cttattttat tgttacctgg atgattcagg
    33061 ttcttgttta tggggcggtc aattgctatg cgttgattag tggctatgtg ggcattaagt
    33121 cgccctataa atattccaaa atcgttaata tttgggtaca agtcttcttt tatagctttc
    33181 tgatgaccct tttgtttgct ctatttggct ttccagttag cttagagaat tggcgtcagg
    33241 ccctctttcc catagtgagt ggcaattatt ggtatatcac cgcctacttt gggttactga
    33301 tttttatgcc tatgatcaat ggtggcctca ataccttatc caataagcag ctaggccgat
    33361 tggtactgct ggtttttgct attttttcgt tgatcccagc tctgatgaac cagcaggtcg
    33421 atgaattttc cttaagcaag ggctttgaaa tgacttggct gattattctc tacattatcg
    33481 gagcctatct aaggaggata gagctaagta ggtttagtca taagcttctt attgcggttt
    33541 atatgggatc tttggtagtt acctatatca tgaaatttat ggtgggaaat atttggtact
    33601 ggtatgtatc acctagcctg accttgggag ctattgcctt atttattctt tttgctaagc
    33661 tgaagctgac atcagaaaca ctgctgctac gctttattgt gatcgtgtct ccaacgactc
    33721 taggtattta tctggtgcac ttacacccct tgctggtcaa atttattatt cgcgattttg
    33781 cagagccctt tgtcaatgct cctatccttt tatacccact actgatattt ggcgtcggca
    33841 ttgtgattta ttttttgtcc tttctggttg aacaggcaag gctgatgctt tttaaaaaac
    33901 taggctttca aaatttgttg aaatgggtgg acaagaaaat cccctttgca gattgatgag
    33961 gaataaggtt agatttagat tgtagaaagg attcacttaa gcttgttttt caagcttttt
    34021 cttttaatca aaaaaacaaa agaattctga aaaatactgt aatatcagca ttttccagag
    34081 ttttcattat atgatagtca atttctaaat tttcaatttt tctatcgctg atagggtttg
    34141 tctacattct gtaagcttgt ttttcaagct tttttgttag caacgaaaaa aactcttaga
    34201 catattgcta tggtgctatg tctaagagta ttatcatgct ggtctatgac cgtaatattg
    34261 aattaaggca ggcccatcaa tgagatttct tatccttttt ttgatgatga aatagctttg
    34321 ctattatggt ctggaccaag gttggtagct tgatgacctt gtcattgcca attgtttctc
    34381 tagcaacctt caagattttt cctgaatcct ttgaagcaaa gagaaatttg ccttgatcgg
    34441 taaagatttc aaagtgacga ctgacctttt tgccagaaac attggcaccg atttggttaa
    34501 tggccgtcca gggaatttga atgaagtcct caacgttttt atcattgtaa aattccaaag
    34561 ccttatctcc aagtaagatt ttcccaacct ttcctccgat tccaagatag gagacggctg
    34621 ttgtctgaag gatcaccctt tgatttaaag attgtgccat aataagtcct ttagtgtttt
    34681 tgtctattat aacataaaaa tatagcttgt agcaggctga atactggcct ttgctaaggc
    34741 tctagacagc caaaaattaa ggaactggga agcccccaat tccttaattt ttattacatg
    34801 atgtgaagaa ggtgtgcgat gataccaaat gcaaacaagg caatgatgat tgcgattggt
    34861 gatacttttt tcttcaataa ccacatgcaa aggaaggtaa gtagtaatcc agcaagtcct
    34921 gggatcaatg agtctaattg cccttgaagg gtttgtgatt gaactttatc aaggctcatg
    34981 ccacccatag cttgtccaag aatacttttt agctcagcac ctttaacggc tccctcaggg
    35041 aagacaacat aggcaccttc agaaagctgc ttgcctggaa ggttgatggt aaagttgata
    35101 gatacccagc gttgtacaag gacagcaagg ataaacatac caaggataga agctccctta
    35161 gtgatgtctt gtaggatacc acctgacatg tctttggtga tttcagatcc agccttgtag
    35221 ccaaattctt gagtgtacca caagaaggcc atacggataa tgttccagcc aaagaagaaa
    35281 aggagtggac cgacaaggtt accagtttgt gcaagagaag caccaagagc accaaggata
    35341 ggacgcactg taaaccagaa gacaggatca ccgatacctg caagaggtcc catcataccg
    35401 atcttaaccc cttggatagc agcgttgtca atagcagtac cgttggcacg ttcttcttca
    35461 agggcaagcg ttaccccgat gataggagca gccacatatg ggtgagtgtt aaagaattcc
    35521 atatgacgct caagtgcagc agcacgatct tctttagttg tgtaaagctt tttaagtgct
    35581 gggataagtg cataagccca acccatgttt tgcatacgct catagttcca agacccttga
    35641 aggaattgtg aacgccacca aacacgttta cggtcagctt ttgttaattt aatttgttca
    35701 gtcattaatc ttaccccttt ctagtagtct tctaggatat cgccgattgg gtcagcagag
    35761 cctgctcgac ctccaccgtt accaccttgt tttgaaaggt taaggtagat aaaggcaata
    35821 gccacaccga taacacccat agcgataagt gttaattggg tcacagctgc aagggcaaaa
    35881 ccaagtgcga agaatggcca tacctcacgt gtagccatca tgttgataac aagagcgtaa
    35941 cctacggcaa caaccatagc accaccgatt tgcatacctt cattcaacca agctggcata
    36001 gccttcaaga cactttgaac ggcctcagtt ggcacagcaa caagaagtgc agctggtaca
    36061 gcaatacgca agccttgaag aagaagtgca gcaaagtgga agcgctcgat agcagagaag
    36121 ttaccctcta aagcagcctt gtccccagcg tgaacaagta cagttgaaat ggtacgaaca
    36181 atcatagtaa ggaaaagacc tgcaaccgca agaggaatag ctgttgagta tgcaaaggta
    36241 atcccttttt gagtaaagtc gccaccctta accatgataa tagccgctgc aacagatgca
    36301 agagcagcgt caggagctac agcagcacca atgtttgccc aaccaagtgc aagcatttga
    36361 agagtaccac caagcataac acctgcttca aggtgaccag tcacaagtcc gattaaggta
    36421 cacgcaacaa gtggttggtg catttgaaat tggtccaaga taccttcaag accggcaaag
    36481 aaggcaacga taacgaccaa gattgcagaa attaatgaaa tatctgacat tttgttatcc
    36541 tttcgtatat gagtcaattg tcaatggaca atataaagcg ttattaagtg atgatgattt
    36601 gtctagaagc aatcatcagg cttatcatat catcgcagca ttgtagatga ggcagacagc
    36661 ttgttgcgtt aaacaagcct acctcttatt tctaaattgc ttattgcaca tttgcttttt
    36721 ggataagctc aaataggttt ttcttagaat catttggcac cttacgaacg tcaaatgaaa
    36781 cacctagatc acgtaatttt tcaaaggcag caacgtcatc cttgtccata gacaatacgt
    36841 tgttaaccat tgttttacct gttgaatgcg ctattgatcc aacgttcagc tctttgatct
    36901 caacgccgcc ttcaatcgca cgaagggcgt cctgaacagt ttcaaacagg ataagagcgt
    36961 gagtgttgcc aaagcgtggg tccttagaag cctcaatcaa tttattgatc ggaacaacat
    37021 tagccttaac cccaccagga gccgcctgct tgatcaattg cttacgaagc tcgtccttag
    37081 ccacagaatc tgacgctaca ataatacgat cagccttaga agctggtgtc catgcagttg
    37141 ctacctgacc atgaagaaga cgagtgtcaa tacgagcaag gttgattttt agcttaccat
    37201 ctccaatgac agttccctta ggaatagctc cttgaagcgc ttgaccacca ccattagctg
    37261 tagaagcctc ctcaactgga ttgagctctt caggaagggc tttaataccg tccttagatt
    37321 ctttaatgat gtttgcggct acttgttcaa cacctgcatt ggcgtccatc aaacgctcag
    37381 tataggcttg aataagcatt ggcaaattta gaccagtgat gatagccatt ttgcgatcag
    37441 gattttctcc tgccacacga ctagcctgat taaatggaga accactccaa aggtcagcta
    37501 gtacaaggat ttcatcatca gcatcaaatt gtgcgatagc attgttgaag tgtccataca
    37561 agtcatctgg tccttcattt ggcatgaaag tcacaacttg aactttctct tgttcaccaa
    37621 aaatcataga accagattga tgaatacctt cagcaaattt accatggctg gcaataataa
    37681 taccgatacc cattcttgtt cttcctcctt attaaaatat ttttcgttga aatgaagaag
    37741 aataatctcc ttccaaatag catttggcaa ttctttttca cttgaacgaa attcaagaac
    37801 gtctctattt taaaacgttt tcacttaaaa atcaagccct ttcggaaaaa tcttacgaaa
    37861 tatgaaaaaa ttttcataat gcgctgccga ataagtagaa tattgataat aaagggattt
    37921 ttatgccgca taaaaaagaa aatatgctga aaaataacga aaatattaga aattctttca
    37981 tcaattgacg gaaacggcat taagaaaacc atcgttttct gaaaaacaat ggtttcgttt
    38041 gctttcacaa gaaaagctct tctagttttc tggcgacccc gtcctcttcg ttagagtaag
    38101 ctagctgctg gtcggcaaag ggcagcagca cagggctggc atttttcatg gcatagccgg
    38161 ttccggcaaa ggccagcatt tctgtgtcgt tatgctcatc accaaaggcg attaaatcct
    38221 taggctcctt gttgtaaatg ctaagcaggt attttaaggt ataggcctta ttaatgtttt
    38281 tgggggacat ctcaaggata tttaagggac caccccaaga gtccacctca atttcgtcct
    38341 tgaagaaggc gcgcatggcc ttggctaggg catacttatc ctcatgatgc gtttgcatga
    38401 gaagagcatt tggatcctgc gtgattttgt cgatctgtaa agccatatct ggtgtgatgg
    38461 cctcaaacca aaaaggttgg ggtcaatgct ctcaggccta ttcatggtaa tgtagaaggc
    38521 ttttcggtac tcactagcaa taaagtccat ctggaagtcc tcctgcactg ctaggagttt
    38581 gagaaggtat gccttatcaa gagtcacatt atgctcgtat ttccatcttt gctcaggtag
    38641 gtgggtcaaa gagccattaa agctaatcat aggtgtcttt agctctagct gaaggtagta
    38701 gtcaatagcc atacgataag gacgtcctgt cgagatgatg acctcatgtc ccttagcttg
    38761 gacggcctta atggtttttt gagtataggt agagatggta ttgtcgtgat gcaataaagt
    38821 cccgtctaaa tcaatagcaa ttagtttttt agtcatacac tagattataa caaattttag
    38881 gatcagtgga agagaaaatt gctgcttgga cggttaatag aaaaaaaggc tgttaaattt
    38941 tgaacgatca tggcaaataa acgaaaaaag ctattgaaaa tagaacgata aaatgttacg
    39001 atgaatatat cgttcgtaaa aacgataata atcatttggt tttaagagaa aaagcttatc
    39061 tgatgagata agggcttttt tgattttgcc tatcaataag gagactccat tcaaatggaa
    39121 aagtttttta agttaaaaga aaatggcacg acggtttcaa cagagctgat ggctggtgtg
    39181 acgacttttt ttgcgatgtc atatatctta tttgttaacc caagtatttt gagtgcagcg
    39241 ggtatgccgt cgcaagcggt gtttttagcg accatcatcg cagctgctat ctctaccttg
    39301 atcatgggtt tgtttgctaa tgtgccttac gcattggctc ctggtatggg acttaatgct
    39361 ttctttactt acactgttgt ttttagctta ggattttctt ggcaggaggc cttggctatt
    39421 gtctttcttt gtggtctgtt taatatcttt atcactgtca caaagcttcg caagagcatt
    39481 atcaaggcta ttccagtaag cctgcagcat gctattggcg gaggtattgg agtctttgtt
    39541 gcttatctag gttttaaaaa tgctaacctg atcacctttt cgctatcatc tgctgagatt
    39601 gttactgtaa atggtgttga gccagctaag gcaactgctg aaacatttgc taatggcgtc
    39661 ttctctgtta atgctaatgg tggtgtggtt ccagctattt caaccttcac cgatccgagt
    39721 gttttgctag cagtttttgg tctgctgcta acagcagtgc ttgtgcttaa gaacgttcgt
    39781 ggagccatcc taattggtat tacagttaca actttagccg gtattcctat tggagtggtt
    39841 gatctttctg ctgttaattt tgcagacaat cacatcagct cagcctttgc tgaattaggg
    39901 acaacattct tggctgcctt tggtggcatg gcgtcactgt ttagtgattc aagtcgcttg
    39961 ccgcttgttt taatgacgat ctttgccttt agtctatctg atacctttga tacgattgga
    40021 acttttgttg ggactggtcg tcgaacaggg attttctctg aggaggatga gagagctttg
    40081 gaaaacagct ctggctttag ctcaaaaatg gaccgtgcgc tctttgctga cgctattggt
    40141 acttcaatcg gagctttatt tggcacctca aataccacaa cctacgttga gtctgctgct
    40201 ggtattgcag agggaggacg tacaggtcta acagctgtat caactgctgt ctgctttgtc
    40261 ttatctgttt tactgctgcc gatcgtggga attgttccag ccgctgcgac tgcaccagcc
    40321 ttaatcattg tcggggttat gatggtatcg tccttccttg atgttgattg gagcgacttt
    40381 gacgttgccc taccgtcctt ctttgctgct ttctttatgg cactttgcta ctctatttca
    40441 tacggtgtgg ctggctcctt tattttctat tgcttggtga agcttgtgaa gggcaaaacc
    40501 aaggagattc acccgattct ttggggagca accttcttat ttgttttgaa ttttatcatt
    40561 ttagcgttat tgtaaacgac taatgaggta cttaggtgcc tcttttttgc tgggacaata
    40621 aagacaggga ttaccgtttg gactgggact atggactttc taagctcata ggcattgcca
    40681 ccttttccta gtcctatatt taggctaagt cttaaggttt tagagctgcg ggttgatttc
    40741 tagagcattc agccctggct atcacagcag aatgccatga tgttaggtcc atgtgatttg
    40801 ctgctggctc ttttgattta tgagatgtta aagctgattg agctttgacg acattatatg
    40861 aggactgacg agcctagaat attttgctga caggctggct taggcttgga agaccgtttt
    40921 ttttctgtta taatagcctt atgttttata gcaaaaatga gaatgaatta atcgcttacg
    40981 ggcaaggcat tggtagacag ctaaaggcag gagatgtgct tgtcttgact ggtgacttag
    41041 gtgctggtaa aacaacgctg accaaggggg ttgctaaggg tttggggatt gatcagatga
    41101 ttaaaagccc aacctatact atcgctcgag aatatgaggg aagactaccc ttgtatcatt
    41161 tagatgttta tcggattggt gatgatccgg actctattga tttagatgat tttatctttg
    41221 gtggtggggt tactgtgatt gagtggggcg agcttttagc caagggaacc ctgcatgact
    41281 accttgaaat tttaataaca aaaacagaaa caggccggca ggttgattat ctagcacatg
    41341 gtcatcgatc agaggcactt cttgaggagc ttaagcatgt ctgagcaggt ggtgacaatc
    41401 gaagaggcca aggcctcaga tgcgtcagct ttgatcactc taattaaaga agctgctgat
    41461 gagacagatt ttatcacagg gactgaggac gtcatagctg ctaccgtaga ggtgcttgag
    41521 tgttttctag aggctagtca ggagtctttg acagatattt gccttttgct aaaggtggga
    41581 gatatattag ctggtctgct aaatatagct ggcaaagcat atcgtgagac tagctatgtt
    41641 ggcgattgct ttatgctggt cttgaaaccc taccgcaatc atggcctagg acagcttttg
    41701 atggagacta cccttgattg ggccagagaa acaaagcagc tttgtgcttt ggagctggag
    41761 gttcaggctc gaaatacttg tgcctatcat atttatgaga aatatggctt taaaatagag
    41821 ggcgtcaaaa gaaaggacgt caaatcaaga aatggagact atcaggatgt ttaccttatg
    41881 cgtaaatatc tggaacgtga atagatgaaa attggaaaaa aaatcttttt aatgctgaca
    41941 gctattgtgc tgttgacctt gggggctatg ggagtttacc taaccaatgc ctataccttt
    42001 tcaactggag aattgtcaaa gacctttaag gattttgcaa cgtcctccaa aaaaagtgat
    42061 gccattcaac agacagagcc cttttcaatt ctattgatgg gagttgacac aggatcgtct
    42121 cacagaacct ctacctggca aggaaatagt gattctatga ttctggttac gattaaccct
    42181 aagaccaaaa agacaaccat gacaagctta gaaagagaca ttctcatcac tttgtcaggt
    42241 ccaaatgata atgagatgaa tggagcagaa gctaagctga atgctgctta tgcagctggt
    42301 ggtgcccaaa tggctatcat gaccgttcag gacttgctga atatcacgat tgacaaatac
    42361 gttcagatta acatgcaagg gctcattgat ttggttaatg ctgttggtgg cattactgtt
    42421 accaatgaat ttgactttcc tatctctatt gcagataatg agcctgagta tcaggctacc
    42481 gttgcaccag gaactcacaa gataaatgga gagcaggcct tggtctatgc tcgaatgcgc
    42541 tatgatgatc cagagggaga ctacggtcgg cagaagcgtc agcgcgaggt tattcaaaag
    42601 gtgctgaaaa agattcttgc ccttaacagt atcagctcct accgaaagat cttgtcagct
    42661 gttagtggta atatgcaaac caacattgaa atatcatcac gaaccattcc taatctttta
    42721 ggctatacag acgcccttaa aaatatcaaa acctatcagc taaagggtga gggagcgacc
    42781 ttgtcagatg gcggctccta tcaaattgtg acctcagatc atcttttaga aatccaaaat
    42841 cgcattcgtg ctgaattagg ccttgaaaag cttagtcagc taaaaacgac tgccacagtt
    42901 tacgaaaacc tttatggctc gttaaaaact cagtctactc aggatagcag ctattattac
    42961 aattcaggta gcctaccggc ctatacagac tcatctaccc agtactcaac ctattcctca
    43021 gagacgtcct ctagcagcag ctatcaggac acaacagctg gtacacaaga gtcaggagca
    43081 gctaatgtga ctcctagccc tcaagcagac tcaccagcag agcagcaatc aagtggtgca
    43141 accactggta cgccagcagc gccttagggt acagccaaaa aaacgaagaa atctcatcaa
    43201 ggcttgatcc tgtgagtgat ttcttcgtct tttttgtaca tacaaaaaga gcccataatc
    43261 cctatagcgg acttgtccac tacagaaacg atagagccct tttttgtcac cttgaggctt
    43321 ggtagtctgc ttaggcttat ggggtttcct gctggtactt gctcatacgt tgttggattt
    43381 cagtcagatg ggcctgagct tcttggttaa aggcctgcca tttgtaggct aattctgttc
    43441 ctgctgcttg aagcgttcga gcctcctttt gaatgatggc gagatttgcc ttaatcctat
    43501 caacatcggc ctggatagcc ttcttagagg tttgcatggc tactagagtt tctttgattt
    43561 gatgacgttt acgatacact tggtaggcta aaacggatgt gagaccaatt gtggtcattg
    43621 tttttagagt cattggctaa tctcctgact aatttgttgt gccaaggctg ctagggctgg
    43681 gaagtcaggc tcatgtgttg tatactgaat agcgatcccg tcttcttggc tgtagcgagg
    43741 aacgaggtgc acatgcgcgt gaaaaacagt ctgaccagct agctcttcat tattattaat
    43801 aatgttcatt gcagtagcac ctgttgcttt ttgaatggcg cgagcgattt taggtaatcg
    43861 ttcaaaggtc tggctagctg tctcggcgtc cattgctagg atatttcgga catgcttttt
    43921 aggaatcaag agggtatgac ccgctgttgt ttgcgaaata tccaaaaaag cgagtacctg
    43981 ctcatcctca taaaccttgg aggagggaat ctcaccgcta ataatgctgc aaaagataca
    44041 attttccatg tgataatcct ttcgtctgcg tagcaatggc tcaaatcagt agttgaataa
    44101 ttttagaata agaaatcagt agttgctcag tgaccatagc tatctcatac tatagttatc
    44161 ttagcatgta ctggtctata ttgcaattgt ttatagctgg tgctaatggt tatcgaccac
    44221 atgactagca aagccttttg aatcatgata atggactaag caattatggt taagcacata
    44281 actaagcctg ctacttgctg caagctaggt ccgtcaaagg tgtgcatttg cgcactatcg
    44341 tacggtagtg acatggcaca atatttgtaa ggacaagagt ttcagagagt atgaggtgct
    44401 ggaacttctt gacagttaag gctgagaaag cttttagaac aaaaaaagat tgaagcgtca
    44461 gcaacatagg ccttatcttc aatcgagtgc ggatggcttt actacaggct agggtcctcg
    44521 ttttgcgaga atttatcagg aacagcccat aggctagggt cctcattttg tgagaattta
    44581 tcaggaacgg cccataggct agggtcctcg ttttgtgaga atttatcagg aacggcccat
    44641 aggctagggt cctcgttttg tgagaattta tcaggaacag cccataggct agggtcttcg
    44701 ttttgtgaga atttatcagg aacagactct tgagcttctt cagagctgac ctgccattcg
    44761 ttagccgtgc ttacttcctg aggcttttca gagatagttt gccagccatc tgtgataacc
    44821 acctcctgtg gcttttcaaa gatagtctgc cattcgttag ccttagcctc tgtttggact
    44881 aggcctgaaa ttgaaagtgc tgaaagtgat accaaaccaa atgttaaaaa gcgtgacaaa
    44941 ttcataacat acctcctttg tcattaaaga cgcaacactt atttacatgt taacgataac
    45001 attatattat taaaaattca atacaataag ataatattat catgattttt tagatgacgc
    45061 cttagatgag ctgctattta ggatcaccag gtcattcgaa tatgatgtga tagatggtta
    45121 ggactgatag atcaagctaa tatagcctct gtttttatag ctaggccttt ttcttgatga
    45181 tcttaaaata gacttcagat tcactcagcg tttttagctg atgggagcat tgatcaaaac
    45241 agttaacgct ctgtgcagaa atttgttata atagctaata taagtgtacc cttagtatta
    45301 gctgccccag ctttcttaag tagggtcaag ctaattggtc ttatcagtgc ttcaaagcgc
    45361 tggataggct gatgatgaca aagcattgcc tagtaagtcc tatctgtcta ggctaataac
    45421 ctgtcatcta gggaagctag tatgcaaagc tacaatagat tagatattag aaagaaatga
    45481 tatgttaaac attgagaatg tcactggagg ctaccttaat attccagttt tgaaggatat
    45541 tagcttttct gtcggaaatg gagagctagt agggcttatt ggtctaaatg gtgctggtaa
    45601 gtcaacaacg attaatgaaa ttattgggtt tttaaagcca tataagggaa ggatttccat
    45661 tgatggctta accttggcgg agcatgaagc tgattatcgc aagaaaattg gctttatccc
    45721 agaaacacca agcctgtatg aggagctgac cttagcagag catatcaata cggtagctat
    45781 ggcctatgat attgatgtgg agctggcaca taagcgagct gagcccttct tagagctgtt
    45841 tcgtttgacg gataagctgg attggtttcc ggtgcatttt tctaagggaa tgaagcaaaa
    45901 ggttatgatt atttgcgctt ttgtcattga ccctagtctt tttattcttg atgagccctt
    45961 tttggggctt gaccccttag caattgctga tttgattaag gctttagagg ttgaaaaggc
    46021 aaagggcaag tcaattctaa tgagtaccca tgtgctggat tcggcagaaa aaatgtgtga
    46081 ccgttttgtg atattgcatc agggacaggt gcgtgcacaa gggactctgg cggatttgca
    46141 ggcagtcttt ggagatgctt cagctagtct taatgacatt tacctagcgc tgacaaaaga
    46201 ggggtaagct atgaaggcat tatttcgtaa gcgtcgtcag gagtttcagc acaagcatac
    46261 caagtatctg ccttatgtct ttaatgatca ttttgttctt gtcttgctgt ttcttttggg
    46321 ctttattctt tttcagtaca gtcaactact caagcatttt cctgctaatc ctctaccgat
    46381 tcagctaggt ttgttgattg ctgtcttgtt tttgcttaat ctggggtcag ttgctaccta
    46441 tcttgaaaag gctgatcagc attttttgct gaccaaggag gcagaggtta ttgcccatat
    46501 caggtcagca gagcgcttgt cctttattct ttggtctagc cttcaaacgg tcttgctgtt
    46561 acctttattt cctttgtttc aaaggcttgg tgtttccttg cttgcctttg tgctattgct
    46621 tggtgttttg gtgctggcta agcgcttact gttaaagcgt aaggtggcaa gctttttgag
    46681 ctccaagggg cttgattggg aaaaagcgat tgcttttgag gcagatcgcc agcaggccat
    46741 tttaaagttt tatgctttgt ttacaaatgt taaaggaatc tcaaccaagg ttaaggaaag
    46801 gccttacttg aatcctatac ttaagcttat caaggcagat agtaaaaagg tttggacaaa
    46861 cctatattta agagcatttt tacgcagctc tgattatcta gggttatggt tacgtctgtt
    46921 gttgcttagt tgcttgtcac ttgcctttat ttccaaccct tatttagcag taggcttggc
    46981 cttggtcttt cattatctaa gtctttttca gttattatca ctttatcatc attatgatta
    47041 ccattatatg agtgggcttt acccgactaa accacagcat aagcaaagga atctactttc
    47101 tttgttgagg caattaagtg gtttgatgct tatcgtcaat cttgtgctct gccgttcttg
    47161 gcaaaatgct cttgtgttga ttgtggcgat gggattatta aatcttcttt acttaccgta
    47221 caagttaaag aagatgattg actaagtcct ttaaaacaag taaaataggg ataactggtt
    47281 acagaagata gaaaaggagg ggataaggtg acaacaaccg aacaggatct tgtattgact
    47341 cccttgcgcg gaaaaagtgg caaagcctac aaagggacct atccaaatgg cgaaagcgtc
    47401 tttatcaagc ttaatacaac accaatccta cctgccttag caaaggaaca gattgcccca
    47461 caattgcttt gggcaaagcg tatggggaat ggcgatatga tgagtgctca agagtggctc
    47521 aatggtcgta ctctgactag agaggatatg aacagtaagc aaatcgtcca tattctgctg
    47581 cgcctccaca agtccaagca gttggttaat caattgcttc agctcaacta taaaattgaa
    47641 aatccttatg accttttagt agactttgag caaaatgcac ctttgcaaat tcaacagaat
    47701 tcttatttac aggctatcgt caaggagcta aagcgcagcc tacctgaatt tcgctctgag
    47761 gtggccacga ttgtacatgg tgatatcaag catagcaact gggtgattac caccagtggc
    47821 atgatttttt tggtggactg ggattgtgtg cgcctaacag atcgaatgta tgatgtggct
    47881 tatttgctaa gccactatat tcctcggtcg cgatgggcag actggctatc ctattatggc
    47941 tataaaaata atgataaggt catgcaaaag attatttggt atgctcaatt ctcttatcta
    48001 actcagattt taaggtgctt tgataagaga gatatggagc atgtcaatca agagatttac
    48061 gctcttagaa aatttagaga aatgtttaga aagaaataat gcgagttaga aaacgaaagg
    48121 gtgcgcagga gcacttggaa aacaatcctc actatgtcat tttagagccg gaggctgcta
    48181 aggggcgctg gtgtgaggtc tttggtaatg atcatccgat ccatattgag gttggctcag
    48241 gcaagggagc ctttatcaca ggtatggcgt tgaaaaaccc agagatcaac tatattggca
    48301 ttgacattca gctatcagtg ctaagctatg ctttagataa ggtcctagcc tctcaggctc
    48361 ctaatgttag gctcttgcgg gttgatgggt caagcctgac caattatttc gatgccggtg
    48421 aggttgatat gatgtatttg aatttttcag atccttggcc caaaagcagg catgaaaagc
    48481 gtcgactaac ctacaaatcc tttttagaca cttataagca gattttgccg gaaaatggtg
    48541 aaattcattt taaaacagat aatcgtggct tatttgagta tagcctagcg agcttttcac
    48601 agtacggtat gaccctcaag caggtctggc tggatttaca tgctagtgat tatcaaggaa
    48661 atgtgatgac tgagtatgag gctagatttg ctaaaaaggg acagattatt taccgcctag
    48721 aagcaacatt ctagtagcta ttttgacaaa aatatgatac actactgagg ttgagttgat
    48781 cagcctttta cttggagagg tcgcatagtg gccgagtgcg cacgcttgga aagcgtgtag
    48841 tccttaacgg ggctcggggg ttcgaatccc ctcctctcct tttatcctat tgatatatca
    48901 aggggttcgg tggtttcacc cgttttttac ccgtcaattt tgagattttg aaaaatgttt
    48961 ttgacctgat ggtcattttt ttcttttaga ctttctatct gatgagcgta aaccttgagt
    49021 gtgatgttga ggttttcgtg acccagcagc ttggatactg atattagatc aacgccctgc
    49081 gctatcaaat aagaagcgta agtatgtctt agcgagtgat tggttagatt tctgccggtc
    49141 actcttttta taactttgtt cgttgcattg tttgacgctc cgaaacagat acgacttagt
    49201 ttattatctt gataatgatt atctttaaaa tattttaata attccacact attgttatca
    49261 atagggacct tcctgatgga ttgctcgttt tttgtaggcc tgaaattttg agaaatcgag
    49321 taatcaaaag ttttattaac atcgacatag ccattgtcaa aatcaatatc tttccatgtc
    49381 aacccttgag cttctgcaaa tcgtaaacct gttatagcta tgatatatgt cgtaaggtat
    49441 gatgggtact tgattttttc cttagcagtc ttgataaaag caaggtattc agattcctcc
    49501 ataaattttt ccgattcttc tttggcgggt ttttgcgacc taacgatggc ttcatcggca
    49561 aaattatccc taataatgcc gtcacgaatg gccattttac aagcaccctt gatttgataa
    49621 tgaaatttat ccagagtttg ttgggctact ttttcgccaa agtcattaag gacttgctga
    49681 taaaaggtgt gtgtgatact cttgagcttc cgagtcccga aataatgttc gatgtgctta
    49741 aagttcttag tatatgtctg ccacgtcttt gcggtaatgt gaggtctttt atatatgtct
    49801 gcccaacgct tgttgtagtc taaaacagta atatctaaaa ggtctgccgt cagcgtgttt
    49861 aaatcagttt ctgcttgctg ggcggcaact tttgcaagtg tttttgtttt aaatccacgt
    49921 tttgattttt ctcttttttt accttgactg tcacgatagg tgatgcgata ctcccacccg
    49981 gaatctaatt ttcgataaaa tgccattgtt ttcacctcat ttttctgtta aaatgggtac
    50041 aagaaaacga gccatttaat gcttttttct tgtatggttt tgcctttcac acaaactttg
    50101 gtcggggagt gtgagaggct ttttttattt aaagaaatta ttaacattta cgtactgagc
    50161 ctgcgtaagc ttagttttta aggttttaac ttctccggtt tgtatatttc ttaaggctac
    50221 cgttgctttt ccaggtattt cttcagaagt ggttgtggca gtagtgttaa tggttccttt
    50281 tttctttcta gccccaccag tcattccacc gacaatggtt ccaacgcctg gtgccaaaac
    50341 tgtacctatt gctgcccctc ctagaacact accagaacgc cctctttgag tagttttccc
    50401 ttttgttact gttttttcaa taattcgtga accatcaaat tgaaggttaa caaactcata
    50461 aagctcagga gtttcagaat aaaaaccaat ataatatttt ccatctatgg tttttcgtat
    50521 ggccgttggt gttcctagtc ctaaatttag ggcagggggt agtatcattt tgctttcttg
    50581 tgaggctttt tttcttagtt cgttagcttt aattgcacca tctttagctt tcccggcagc
    50641 tgctatggca aatcctttta atttagttat atccatgctt atctccttaa ctaattaaaa
    50701 actctaattc ttccttgacc atcacttcgt cagcgattga ggtcagttca tatttttcca
    50761 tgaattggat gtagttgaaa tcctccatat tatcccaata cgatagctct tcttttaaga
    50821 gatggtgtat catacatcta tctgcttgta gctctgcttt ttctttgttt agtttgtaat
    50881 aactcgcagt atgttctctg tgtcctagtt catgatagat gactttgtgt ttatatatac
    50941 cgtcaagata agtgtcaatc gcaatgacgt tgtgtttttt attaaacatt ccgggggtgt
    51001 ttgtacccct accgtcaaag tatactaaat cgattccttt ttcctgacag actgtttctg
    51061 gtgtcatcat agagcagtcc tctctatttt ctatttttga tgcgcgtttc caatatagat
    51121 gtgataagat ctatatcctc gtcgttgagt tcgtggccat cgaagaagaa agtttcttct
    51181 gcatcttttt tcagatcaat tgcgacagaa gcgtgcccat cttgagcaat cttaggatta
    51241 tctgtcctgc caagtaaata gtcggtagaa acattaaagt agttagctat tttttctatt
    51301 gggtctgtat tagccgtttt tttacttttt aaattataaa tatagttttc gctcaaccct
    51361 atatcagttg cgaccttttg gagagatact cctctttttt tagctaaggc ttcaattctt
    51421 gaatacacct caaacattgt catatcaacc tttctgaaag tatgacaaaa aatatttaac
    51481 tttttcgagt aaaaattatt gacttagttc acacgataga gtaaaatagt ttttgtaaga
    51541 tagttagtta gtaaaaaacg aagttaaact ttttacaaat ctttttaaag tagttgggga
    51601 actgcgcaat ataaaagagt tataaaggtt ataactaggt ttttcttatg ccttcatttt
    51661 acattaacgt gtaaaataag tcaacacaaa aatgttattt ttttactaac tttcttactt
    51721 acaaaaataa aacaccacct agctgctatc tagatggtgc tacggaaatt attctgctca
    51781 aactaatagc agtagtcaac aacacttcac cggtatcgtc cccggcactg tagttggagt
    51841 agaaaatgat tctcgatttt gatttcctat tcttcgtcgc ttttgcgagc gacagccagt
    51901 ttgcaatttc tgtggtcgtc cggccaggac gccaatgaag atataggaac ccctattgaa
    51961 tcttgctagt caagtgcggt aggcaaaagg aaaacctaca aacgaatcca tcttctactg
    52021 agacacagtc tccttcaaaa actcggacaa atgatacgtc ctcctttcat acaaagggta
    52081 tttacattat atatttgtaa gtcgaaaaaa tcaagatgga tactgtttga atcgagcaga
    52141 ataacgtttc cgttaagttg ttttaaataa atctacttac tagaaaggag tctaacgcat
    52201 gtcagacaac acggtcgctg ttgaaaaaat taagaagtat ctgcttgaca ataagctaaa
    52261 acaagttgac ttagcagtta cctataataa agaaccgcaa gatgtggcga atatcttagc
    52321 tggaagaaaa aaagatccag catcaaatcg ttttgtcttg aaagttattt cagatttgaa
    52381 aattagatag aagagaatta tatgaaccaa ttgcttaacg caatactaga aaggaacctt
    52441 atgacagacg cagaaaaaca aaactatgat gcccttttca ttaatatttt tgaacgttta
    52501 gaaaaactgg aggaaggcta tgattttagc tccgtagcta caactacggg ggtccaaaat
    52561 agcggcggtg ttcaatatcg tgaatgccaa gaagacggaa ctgtagtcaa aacagtatcc
    52621 aagaggagct taggctactg atgattatat caaaaaagtc cgacgggaat cgggctcaac
    52681 aataatactt atgaggtaat tttatcatgg atagcagatt attacaaatg ctagatgagt
    52741 ttgaagcagg ccttattgat cgcaaggtca aagtcatgaa aatgattaac aatgaaacgg
    52801 aaacttatcc gctagaactc aataaaaagc aagtcagtaa aatgtttggg attgacccta
    52861 aaacatttga cgcaagattt aacagccaca aagatttccc acgtatcgaa acgggaggtc
    52921 gggaaaaata tccacgagac ttggtcattg agtggtatca cagaaattgg agtataacat
    52981 gaacaaacta gaattatttt tattagcgac aacaatcgtc ttagcaatca tcgctagggt
    53041 gcaatatgaa attattaaaa aacataactc acccgagaat aagcgaaaaa tttttaggga
    53101 agtagcttta gaaaacagca agaaatggag tgcagaacgt tatgtctaaa tgggaattac
    53161 aaaaacaact actggaaaat gcgacagatt ttgagagcac agttgaggct ttacttgact
    53221 taaacgagtc tggcgaaata tctgatctgg aactcttact gaacttaaag gataaattca
    53281 gaagctattc caaagaaaaa atacgtatcc ttaatgaaat tctcaagcta ggaggtgcag
    53341 aatgatgaca acttttgaaa agattattaa gaaaattaat cggattgagg gggagttagt
    53401 taaacctgaa gctgaaagac gagatagctt acctatccta tctgctcagt tgggttctat
    53461 taaacaagat ttaaaattga tgctttggat tgagctgcct tcgttaaata atgtggagaa
    53521 atacgaagct ctttatcaag gaaatgattt taaattcagt gaaactttct tagagcgtca
    53581 agcgacaaga aaagcctttt ggagacgatt agctaaggaa acttttaaag aagaccagga
    53641 taggaggaac tttgttaagt tggctgagaa agaatttaaa ggtgcaactt tgtcatggca
    53701 agaatttttg tggggtaaaa agaaatgaat atttcaataa aactcatagg tgaaacccta
    53761 gctggtttaa atgatatttt acgccagggg gggctctctt gctcccaaaa ccaagcctta
    53821 gcagacgcag tttttatatt aacagcttta aaacaagtaa ttgaggagag aaaatgaact
    53881 atttagaata tgcactagtt tatcttgaac gtgagttaga aattattgat aacgaagtta
    53941 tcgaagttga gttgccgggc ggggattggg agtttgtgcc taatccctac tacgagaaag
    54001 gtctacatga tagcccacac tatcgtagtc aggttgctaa agacattctt gatattaaag
    54061 gacttttggg gaggtgaggc tattgattgc atcaaaaaag acggcttagg aaaccgtcaa
    54121 caattataca cacttaaatt ataacacaga aagagagaaa cacaatgatt gaagtaactt
    54181 ttaaagcaga gagcatggca ggtgttttcg atgctatgcg tgaagctctg gatatgccga
    54241 agacagtaac caaggatgtt gttgaagaaa aaccagctcc taaaaagaaa gaagagtctg
    54301 taactttgac attagctgat attaagaaaa tggctaaagc caaggttgaa gaagggaagt
    54361 caaaggacat caaggaagtc ttgaaagaga tgaacgtcgc aaaagttggt gaacttgaag
    54421 aataccagtt tgcggagttt gttgagaagt tggaggctct ctaatgccag tagaaaatca
    54481 cgcactactg tctgcttcta gtgctcacag atggctctat tgccctatgt tacctagact
    54541 ggaagcagac tatcctagcc gcgacaccgt atacactcaa gagggcacaa gcgcccacga
    54601 gctttctgaa atcaaactga tgtacaagtc tggtaaaatc accaagcgta aatttaacac
    54661 gttaaccaag acttttaagg aaaactcaga cttctacaac gaagagatgg aagagatgac
    54721 ggagctttac acagatattg ttatggagca cctaaatgct tatgagaacg ccgaaattga
    54781 acttgaaaaa cgggttgatt ttagcgactg ggtgcctggc ggttttggga cttcggatgt
    54841 cgtcattttg gcggatggag tcattgaaat tattgatctt aagtatggta agggcatgcc
    54901 tgtgtctgct aatcaaaacc cgcagatggg actgtacgct ctaggagctt atgcttccta
    54961 cgatatggtc tatgactttg accgtatcaa gatgactatc attcagccgc gtttagattc
    55021 ggttagttct gttgacattt acgtggagga gttactctac tgggcggata atgttgtctt
    55081 gcctatggcc gctcaagcag acgcaggcat tggtgactgg aacctaagtg aaaaagtatt
    55141 gcagtggtct cctgtcgcag ctaaattggt accaagagcg caagaaaatt gggaattaat
    55201 tgataaatat gactatcagg agcctgtcta tttatctgat gaagccgtcg cagagatcct
    55261 tgacaaagcc tcagctatca agaagtgggt tgagtcagtt gaagcctatg ccttgaaaga
    55321 agcactctca ggaaaagaag ttccaggcta taagattgtc gaaggtagaa gtaatcgagt
    55381 tatcactgat aaagacaaag caattgatat tttacaagat aacggctttg acgatgagat
    55441 ttttaaaccg aaagagctgt tagcaatggg agcccttgaa aagttaatag gtaaaaccac
    55501 ttttgctgat ttattagcag aagtaattga taaaccacag ggcaaacctg tacttgtccc
    55561 tgaaaaggat aagcgcccag caataaacag tttagaacaa gcaattaaag attttgaata
    55621 ggagaaaaat aattatgaca acaacaccaa acacaactaa agtagtgacc ggaaaagtac
    55681 gcctaagcta tgtagcttta ctagagccta aagcctttga aggccaagag gctaagtatt
    55741 caacagttat cttaattcca aaaacagaca aagtcacaat caagaaaatt aaagacgcgc
    55801 agaaagctgc ttatgaggct gccaaggaca ataaactcaa aggggttaaa tgggagcgcg
    55861 ttaagacaac gcttcgtgac ggcgacgaag aaatggatac cgaagagcac ccagagtacg
    55921 ctggacacgt gttcatgtca gtgtcaagta aaactaagcc acaaatcatt gacaagtata
    55981 aaaaccccgt tgactcagcg gatgaagttt actctggcgt ctatgctcgc gtatcactta
    56041 atgcctatgc ttacaacaca gcgggaaata aaggaatctc ttgcggatta aacaacgtcc
    56101 aaattgttgc taaaggagac taccttggcg gccgttcgtc agctgatgca gattttgacg
    56161 agtggaacga agaagaggac gaagacgata ttttatagta gagagcctct ttagaggctc
    56221 ctcattttta aaggagaggt atgagacatt taaatattga tattgaaacc tatagttcga
    56281 atgacatcaa aaatggggtt tacaagtacg ctgacgctga agattttgag attttacttt
    56341 tcgcttactc tatagatggc ggagaagtag agtgccttga tttgacaagg cagtctctac
    56401 ctgaagacat caaagatatg ttatttgatg ataaagtccg aaagcacgcc tttaatgccc
    56461 aattcgaaag agtttgtctc agtcgttacc tcggcctacc ttactatcta gatccttgcc
    56521 aatggcaatg caccatggtg ctggcccaag agttgggtct gccttcaagc ttggaaaagt
    56581 gtgcgctgta tttaaaatta gcacaggaaa aagatacctc gggtaaaaac ttaatcagat
    56641 acttttccct gccttgcaaa ccaagtaaaa ctaacggtgg gagaactaga aatttaccag
    56701 aacacgcccc cgaaaagtgg caaatgttta ttgactactg tatccaagac gttgttgttg
    56761 agatggcaat cgccgaaaaa ctagaatcag ttcctgtgca cgaccgcgaa tgggactact
    56821 acgcctgcga ccagagaatc aacgacagag gcgtggcact tgataaagag ttagttgctt
    56881 cggctttgta ttgtaaagat gttaagatgg aaagtttgtc tggtgagcta aaagccataa
    56941 caggacttgc taacccaaac agtagagctc agttgctacc gtggctaaaa gaacacggtt
    57001 attcggctaa cgggctgact aaagcagatg ttgaacagga acttaagacg gctgaaggag
    57061 aacttaagag agtcttagaa cttaaactac aaaccgctat gtcaagtcta aaaaaatatg
    57121 aagctatgga aagagctatg tgctcagacg gacgagttca tgggctactt cagttttacg
    57181 gggctagccg gacaggaaga tgggcgggca gagttgtcca agtacagaat ttagctagga
    57241 attatataaa ggatctagat gatgccaggg agtatgttaa aaagcgtgac attgatgctg
    57301 tggagatttt atacgatagc cttaatgaca ctctaaagca gctcgtgcga accgctctcg
    57361 tggctaaaga tggctgtacc ttctatgtct ctgacttctc agcgattgag gctagggtga
    57421 ttgcatggtt tgctggagag cagtggaggc ttgacgtgtt ttcgacgcac gggaaaatct
    57481 acgaggcgtc tgccagtcag atgttcggaa ttccaattga ggagattgac aaggaactac
    57541 gccaaaaggg caaaatttca gagttagcac ttggctatca aggaggtcct ggagcgctta
    57601 agcagatggg ggctctaaat atgggagtca aggaagagga gcttcaaggg ttagttgatg
    57661 actggcgcag ggccaataag aaaatcgtcc aattttggaa agacgtacaa agagccgcca
    57721 tcaaagccat caaatcgaga gcaccgataa aacttggaaa actacgattt agataccgga
    57781 aaggtttcct ctttataaca ttgcctagcg gtaggaactt agcttatgca agagccaagg
    57841 ttgagccagg cgactatgga gacaaaatca tctatgaggg ccaaggagat aaggcctact
    57901 tcacagcgca agagacttat ggcggtaagc ttgtcgaaaa tatcgttcag gcgacggcta
    57961 gggatattct agccgaagcg cttctgagaa ttgaagctgc aggctatggt gttgttttcc
    58021 acgttcatga tgaggctatt atcgaaggct caggcctgac aatcgaagag gttaatgatt
    58081 tgatggctca ggctcctgaa tgggcggagg gtcttccttt aaatagcgaa ggctatgtaa
    58141 caaagtatta tatgaaggat tagatagatg aagcaagaaa aactaatagt aaagtcttct
    58201 cccctgcaag agcttcatat cgcaacaggt agttcgcgaa cagctaagac atggaaaaat
    58261 atcacgctaa cttggcagga gctggttgag aggttagaga aacctacagt cacccaagag
    58321 acgtttgcgg agtaccagaa gatgtctcga gcagaaaaag ggcaagcaaa agacgtaggg
    58381 ggctttgtcg gtggatggct aaagcaaggt aagcggaaaa atgaaaacgt tcaaagtagg
    58441 tccttggttg cgcttgacgc agatagccca agtaaagatt tcttagatag gctagacctg
    58501 cttgcggatt atgcctacgt actctacagt actcacagcc actcaaaaaa agctgctaag
    58561 taccgtctta ttatccctac tgaccgttta atgatgcctg atgaatatga gccagtcgct
    58621 agatatttgg ctaaccaact aggcatgtca aactttgatg acacgactta tcaaagcgtg
    58681 cgcttgatgt tctggccgag tcactcaaga gatgcagact ttacgtttaa atataacgac
    58741 gaggcttttc tgagtgttga tgaggtgctt gatacatacc cggactggca tgactcaagc
    58801 ttctggccag aaagcccgac gcacgctgtt aaaagacagc gtgaagctaa aaaacaaggt
    58861 gacccgctta gtaaaaaagg acttattgga gccttttgtc gtaactatga cattagacag
    58921 gccattgcaa cattcttacc tgaggtttat gaagaaggaa cgactcctga taggtacacc
    58981 tacactgatg gctcaaccgc aaacggctta gttatctatg atgatgtctt cgcttatagc
    59041 catcacggga cagatcccgt gggggatacg cttgtaaatg catacgacct tgttcgtatc
    59101 cataaattcg gagagcaaga tagcgaggct aaagataata ctcctactaa taagctacca
    59161 tcaagcaaag cgatgaatgc ttttgtctgt gacttacccg aaattaaaga ttatctaatg
    59221 gcggaggctt taggcgattt cgatgaagag ttaccagtcg aagatgacag aagctggctt
    59281 gaaattgatg agaggggcga accggaggtc aatagttatt tgctagcaac gcagattatt
    59341 aaggaggttc cgatttattg ggatggctta gaatttttac gctacgacgc taaaaaaggc
    59401 atctggttgc caaacgctga ggaatatttg aagagttata tctcaactaa gaaactcggt
    59461 aaaatcacta agattaggca cattagcgaa accattgtag cgattaaagc acaggctttc
    59521 tcaagcgaag tgtttaccga gagtgatctt aacaagatag tgctagtaaa tggagtctat
    59581 gacctgaggg ataacagctt taagactaag tttgatccag aattgcatgc caggtcaagc
    59641 catcccgttg cctatgcccc cgaggcggcc tgtgaaacct ttgagggttt tcttagggag
    59701 accgtcggag ctgaaaatat agatttcatc tttgagtggt ttggctataa cttttatcgt
    59761 gaatacacta ttcaaaaaat gctattcatc tatggcagcg gcggtacggg taaatcaaca
    59821 ctgattaata ttttacgtga aatgataggt gctgataatt attcagccgt gacactgcag
    59881 tacctgatgc aagaacgctt tgcaaaaatc ggcttatatc gtaagacagc caacttcgat
    59941 accgatgcta aacctcaata cttagcagat ggcgcaacgc ttaaaatgtt gactggggaa
    60001 gatacgatac acgcagaccg gaaaaacaaa gagcctatta atttttacaa ttacgccaag
    60061 ctgtcttttg ccatgaatga gctcccacct atgcgagatt tcagtggagg acttaagcgc
    60121 cgcatgatga tccttgagat ggataaggta ttaacgcagg aggttaaggc aaaataccca
    60181 ctagataaga ttatgagtga ggtgcctggt atctttaaca gagcgatgga ggggcttaga
    60241 aatgccttaa gtaagagaga tttcagtatt agtgccagca tgaggtcaag tgtcgagaaa
    60301 tgggaaaaag gcaacgatgt cgtggccatg ttccttgaag acgagtgtga acttggtgaa
    60361 gacttcaaag ttcctgttag ggacgtctac ccagcctata aattctattg tcaggattca
    60421 ggctacaaac ctttagctag gaattcgttt acgcaaagga tgaatgaact gaattttgaa
    60481 aataagaacg caaaaatggg gggcaagacc gtaagatgtt ggataggttt taggataaaa
    60541 ggagaatttt aaagggttac gtttttcaat aaaaaaggta aacaggagac ataaggttac
    60601 gtagttacgc agaattcaga ctgataaaaa attttataag ttgaaaaaaa acgtaactac
    60661 ataactttcc tgaaaaaact ttcctgttta agtcgattta cataactaac gcaactttta
    60721 tgcaacctca aaaaaccttt catagcaata gtttagaccc taaggttatg tagttatgtt
    60781 ttttcttcta ttaacttaaa tataaatata aaaaataaat atatataaaa taaggcatat
    60841 ataaaacacg tatataaaaa agaattaata agttgaaaaa aaacgtaacc ctgaccttta
    60901 ttgaccaaag gaggaaagat gaggactgaa aaagatattg aaaattattt gaaaaagaaa
    60961 acaaaagggc tgtgtttaaa atttaccagt ccagggacga taggagtacc tgacagaatt
    61021 gttgtcatga atacgggaac cttttttgta gaggtcaaag cgccaggcaa aaaaccaaga
    61081 cccagccaag ttgccatgca caaaaaaata aaagaggctg ggcagcacgt ttgggttgtt
    61141 gactcctacg aatcagtgga catggcctta aaagaaatgg agaactgggt gtgagactgc
    61201 acgagtacca agaatacgct aagacatgga tagtagagca cccttattgc ggccttttac
    61261 ttgacatggg ccttggtaaa acgctgacaa cactatcggc gatagatgag attcaaaata
    61321 ttttttccga ggatcataag attttaatcg tagcccctaa aaaagtggcg gaagaaacgt
    61381 ggcctacgga gattgagaaa tggcattttg atttcaccta ctctaaagtt ttggggagcg
    61441 agggaaaacg aattgaggcg ttagaaacag aagctgatat ctatttgatt aatcgtgaga
    61501 atgttacttg gcttgttgaa tactacaaga ctaaatggcc gtttaccttt gttgttattg
    61561 atgagctgtc aagctttaag tctagtaagt caaaacggtt tagggctttg cgaaaagtta
    61621 gaccgaaagt ccaacgcctt gtaggactaa caggaacccc agcgcctaac agtttgattg
    61681 atttgtggcc gcagatttat ctgatggaca gaggcgacag gcttgagact agccagactc
    61741 gatttaaaga caagtatttt gttcctgata agcgtaatgg tccaatcgtg tatagctgga
    61801 cacttaggga tggtgcagaa gcagaaatct ataacaagat tgaggatatc tgtgtcagca
    61861 tgaaagctaa agactatctc aagttaccgc cgcgaaccaa caacgttgta tcagttaagt
    61921 tatctaatat gaaagcttac aaacagcttg aagctgattt ggtgttggag tttaaggata
    61981 aggaaatatc tgcggctaac tctgcggttt tggtcaataa attactccaa atggccaatg
    62041 gcgctatcta tgatgctgat aaaacgacag ttgctataca cgatgacaaa cttgacgcgc
    62101 ttgaggacat agtagaagaa agccaaggcc agccaatctt agttttttat cagtatcaac
    62161 atgatcttga aagacttaag aaacgattcc ctcaggctga agagttgacg tcagttgaca
    62221 agtggaattc tggaagaata ccaattcttc tgtgtcaccc tcaatcagct gggcatgggc
    62281 ttaatctaca aaaaggcggg catattattg tttggtttgg gctaacgtgg agtcttgaat
    62341 attatcagca agctaatgcc agattagata gacaagggca gacagaaccc gttattgtgc
    62401 accacattgt tgcagaaaat acagttgatg aaaaagtact taggatttta caaggcaaag
    62461 aaaaaaatca gaacgcctta cttgaagcag ttaaggcgca gttaggggtc tagatgaaaa
    62521 aagaatatgt cgttagaatc tacacgggta gagaaaagaa ttttgaggca aaacctcagt
    62581 ttgaagagaa aacctttacg cgaaaagcag acatgttgag gttttgggat tcttgcgaag
    62641 cagcagttaa agaaaaatat actagggagt ggaaaaaatg acaaaacaag aactaattga
    62701 agaaatagaa gatgaaatca atgacataga tcttttgatt gacgattacc aatacgaaat
    62761 tgacgaatta gaacgagata tagacgaatt agatactcaa aaagatattt tgaagcgtaa
    62821 attagataac ctgttagaaa gcgtggaatg atgactgaac aacagatgat tgattgcctg
    62881 ctttatgagt tagcaaaaaa agacaaagca atcaaaaata aaagcatcat tatcgctgta
    62941 ctaacagctg tgctgtgtct cgtgtctgtt ttaagcatcg cactgcaaaa ccactacgaa
    63001 ccacaaatta caggtttaca gtcacaatta cgcaggacgc agtatcagct taagcgagct
    63061 agcgaggata gagctagaca gacaaaacgg attgcagaat tgactggaaa tgggggatga
    63121 ttatgttgct aattgacgaa gtaaaaaaat gtgaatcatc ttatgagata tttagtaaac
    63181 cagttgtact aagtagagat ttatatattt tttggaggat aggagatgag gatggacaat
    63241 aacacagcag ctgttttgac actgctaata ctatttttac cttttattat tggaagtttt
    63301 agagattaag cgaggtaacg agatgagtag attatctaat gcacagctaa aggcttttga
    63361 tgaatggctg tttgattatc gctttattga taacaagatt gcacttcgaa aacttgagct
    63421 acaaactgac atgaatacag aagtagataa aaatatcggt ggaggaagag caaattttgt
    63481 ttcaaaagtt actgaggatg tggttgcaag gtgggattca gatagggaac taaagggtct
    63541 atccaatttc aaagaagcag ttattgcaac gctaaatctt ttggatgaag aactaactga
    63601 tatttttaat cttaggtggg gcgtcggttc aagtaacact tgggaagaaa ttgcctatac
    63661 aagacatctg tcgcgtaagt ctatttaccg caaaagagag cggattctag aaatattttc
    63721 caaaaaaata ggaatgtgac acaaaaatgt atggaattgt catctttttg atgataaatt
    63781 ggtagtatga gtttgaaggt aaggcagata gtgtcttgcc tttttgctat gcttggaggt
    63841 gatggaaaat tgagtaaatt aaccctaaaa cagaagcgtt ttgcagatga gtacatcatc
    63901 tcagctaacg cgacagcagc ggctattaaa gcagggtata gtaaaaagac agcaaggtca
    63961 ataggtcaag aaaacttgac caaacctgac attaaagctt atatagacga gcggcttgaa
    64021 aaacttgaat ctgaaaagat tgctacgcaa gaagaagtcc tacaatatct cacttcaatt
    64081 atgcgaggag accaacaaga aaagacgctc attagcgttg gagagtttgg ccagaagata
    64141 gttgacatcg atgttggtgc caaggataga atcaaggcag ctgagctact aggcaaacgg
    64201 tacaggttat ttactgacaa ggttgaaatg gatgtcagct cagatgtaac cattaacgta
    64261 ggtgagtggg atgacgacta aacagcgccc taaaattaat atcgtgatca agcatcctag
    64321 caaagttttt aacaaacata tctacgacaa actttacaac tatagcaact tcacggaagt
    64381 tcattatggt ggggcgtcta gcggaaagtc tcacggtgtt tttcaaaaga taattttaaa
    64441 agcacttaac cccaaattca aacatcccag aaagatatta gttctcagaa aagtcggtgc
    64501 aaccgttaga gactctgtat ttgctgatat catgtctaat ttgtcgtatt tcggcatctt
    64561 ggataaatgt aagataaata tgtcggcttt tagaataacg ctcccgaatg gctcggaatt
    64621 catttttaag ggtatggata accctgagaa gattaagtca attaagggga tatctgatgt
    64681 cgtcatggaa gaagctagtg aatttacgct tgatgattat acgcagttga ctttgcgttt
    64741 aagagataag aaacatctag agaagcaaat atacttgatg tttaaccctg tgtcaaaagt
    64801 aaactgggtt tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac
    64861 aacttataaa gacaaccgct tcttagatga tgtcacgaga gaaaatattg aggaactagc
    64921 cgataggaat gaagcttact acaaaatata tgctcttggc cagtttgcta cacttgataa
    64981 actaattttt cccaaatatg acaagcaaat attaaacaaa gacaagttat cacacttgtc
    65041 ttcttttttt ggtttggact atgggtttat caatgaccct tcggcatttt tgcatgttaa
    65101 aatcgatgac gcaaacaaga agttatacgt catagaggaa tatgtcagaa agaatttgac
    65161 caatgacaaa atagcaaatg ctataaagga cctcggctat gccaaagaag aaatcagagg
    65221 agattcggct gaaaagaaat ctaaccaaga gctgaggaat ttaggtattc ctagaatgat
    65281 tgatgttacc aaagggcctg gaaccgttat gcaaggaatt cagtacctgc ttcagtatga
    65341 ttgggttgtt gatgaaaggt gtgtcaagac tattgaagaa ctcgaaaatt acacttggaa
    65401 gaaagacaag aaaactaatg agtatatcaa cgaaccagtt gacagttata accactgcat
    65461 tgacgccata agatatgccg tacaagacag aatataccag tcggcggata gaagtaagcg
    65521 catgaaaaat gctaaatatt atttttagga atgaggtgag actttggaag aaaaacaatt
    65581 tttagcagga actcgtttta atgagaatgc taataagcaa tttattatgc tgcaagaaga
    65641 ctttgaagca attgactatg aatcaaaact ttggatagat caacttaaga attacatttc
    65701 aaggtttaaa gcagaacaat tagagcgttt gaaagagtta aagcgatact atcttgggga
    65761 taataacatc aagtatagac ctgctaaaac agataaatac gcagcggata atcgtattgc
    65821 aagtgatttt gctaaatata ttacggtatt tgagcaaggt tatatgcttg gtgttcccgt
    65881 tgagtacaaa aatgaaaata aagacctcca ggcggctatt gaccttatgt cggtcagaaa
    65941 caatgaggac taccacaacg tcaaaataaa aacagattta tcaatttatg gaagagccta
    66001 cgagctgtta actgttgagg aaatagatga caaaaaaacc gaagtaaaac tctaccagct
    66061 cccagccgag caaacttttg ttatctatga tgatacatac cagcgaaatt cgttgatggc
    66121 cgttcatttt tacgacatag attatggctc aggtaaacgc aaacagatta tcaaagtata
    66181 tacttccgac acaatttaca cctacgaaga ctataatctc gaaacaaaag gtacgtgctt
    66241 aaaagagcat gaagaacatt tttttaaagg tgtaccagtc aatgaatatg ctaataatga
    66301 ggagcgtaca ggggcttatg agtctgtact tgataatatt gatgcctatg atttatctca
    66361 gtccgagctt gctaattttc aacaagattc agtcaatgcg ttgcttgtaa tagctggtaa
    66421 tgcttacaca ggggctgatg agaatgacta cttagatgac ggacgattaa atcctaatgg
    66481 tcgcttagcg atctcaattg ggtttaaaaa agcccaagtg ttaattttag acgataatcc
    66541 taatccaaat ggcgttaaac cacaagcgta ctttctcaaa aaagagtatg ataccgccgg
    66601 tagcgaagcc tacaaaaata gactagttgc agacattttg aggtttactt ttacgccaga
    66661 tacacaagat atgaaatttt caggagttca atctggtgaa tcaatgaagt ataagcttat
    66721 ggcttctgac aactatcgcg agaagcaaga gaggttgttc aaaaaaggct taatgcggcg
    66781 cttacgctta gcagctaata tctgggccat caaagggaat gaagcaacta catatagcct
    66841 tgtaaatgat acgagtatag ttttcacacc taatcttcct caaaacgata atgaaattgt
    66901 tacagctgca caaaatcttt atggcattgt tagcgatcag actatctttg aaatcttaaa
    66961 cactgtcaca ggagtagacg ctgaagcaga gcttgaacgt ttgaaagaag aagctgataa
    67021 aaagcaatct ttaccggagc ctagattggt aggtgatgct agtggtcaag aagaaccaac
    67081 agcagaaaag ccttaattac tggcaaaagc gtcaagaaga tattctaagt tatttagaca
    67141 gagctgattt agatgtcttt tcagaactgc agaagttata taatgaacag gcttttgagt
    67201 tacaaaagga attgtttgat ttttatacta agtattctga agagaacaaa atgacttatc
    67261 aggatgtcgt taaaaagcta cgtcatgaag atttatcaga ttacgtagct aatgctaaca
    67321 agtatcgcaa acaagctgag aaaga
//
LOCUS       DARYJX010000004        66929 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYJX010000004 DARYJX010000000
VERSION     DARYJX010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66929
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(383..2557)
                     /gene="nrdE"
                     /locus_tag="TU257_000223"
     CDS             complement(383..2557)
                     /gene="nrdE"
                     /locus_tag="TU257_000223"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0833289.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2604..3011)
                     /gene="nrdI"
                     /locus_tag="TU257_000224"
     CDS             complement(2604..3011)
                     /gene="nrdI"
                     /locus_tag="TU257_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0833290.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3013..4026)
                     /gene="nrdF"
                     /locus_tag="TU257_000225"
     CDS             complement(3013..4026)
                     /gene="nrdF"
                     /locus_tag="TU257_000225"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0833291.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4707..6710)
                     /gene="metG"
                     /locus_tag="TU257_000226"
     CDS             complement(4707..6710)
                     /gene="metG"
                     /locus_tag="TU257_000226"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL0833292.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6928..7626)
                     /locus_tag="TU257_000227"
     CDS             complement(6928..7626)
                     /locus_tag="TU257_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL0833293.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8012..9033)
                     /locus_tag="TU257_000228"
                     /pseudo
     CDS             complement(8012..9033)
                     /locus_tag="TU257_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9568..11247)
                     /locus_tag="TU257_000229"
     CDS             complement(9568..11247)
                     /locus_tag="TU257_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833294.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(11422..16326)
                     /locus_tag="TU257_000230"
     CDS             complement(11422..16326)
                     /locus_tag="TU257_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0833295.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            16679..17506
                     /locus_tag="TU257_000231"
     CDS             16679..17506
                     /locus_tag="TU257_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL0833296.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(17582..17935)
                     /locus_tag="TU257_000232"
     CDS             complement(17582..17935)
                     /locus_tag="TU257_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL0833297.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(17939..18451)
                     /locus_tag="TU257_000233"
     CDS             complement(17939..18451)
                     /locus_tag="TU257_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL0833298.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(18908..19462)
                     /locus_tag="TU257_000234"
     CDS             complement(18908..19462)
                     /locus_tag="TU257_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833299.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            19673..20302
                     /locus_tag="TU257_000235"
     CDS             19673..20302
                     /locus_tag="TU257_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL0833300.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            20761..21846
                     /locus_tag="TU257_000236"
     CDS             20761..21846
                     /locus_tag="TU257_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833301.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            22032..23243
                     /locus_tag="TU257_000237"
     CDS             22032..23243
                     /locus_tag="TU257_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0833302.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPRGENPTPTPDPMPQPMPDPAPKPESKP
                     EPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVLGTGLLSLLG
                     LGFLTRRKRKQ"
     gene            23559..24650
                     /locus_tag="TU257_000238"
     CDS             23559..24650
                     /locus_tag="TU257_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0833303.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTN
                     EAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(24783..25901)
                     /locus_tag="TU257_000239"
     CDS             complement(24783..25901)
                     /locus_tag="TU257_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833304.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(25898..27025)
                     /locus_tag="TU257_000240"
     CDS             complement(25898..27025)
                     /locus_tag="TU257_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833305.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(27034..27957)
                     /locus_tag="TU257_000241"
     CDS             complement(27034..27957)
                     /locus_tag="TU257_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833306.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(27980..28666)
                     /locus_tag="TU257_000242"
     CDS             complement(27980..28666)
                     /locus_tag="TU257_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL0833307.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(28663..29334)
                     /locus_tag="TU257_000243"
     CDS             complement(28663..29334)
                     /locus_tag="TU257_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0833308.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(29309..30667)
                     /locus_tag="TU257_000244"
     CDS             complement(29309..30667)
                     /locus_tag="TU257_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL0833309.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(30680..31744)
                     /locus_tag="TU257_000245"
     CDS             complement(30680..31744)
                     /locus_tag="TU257_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL0833310.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(31741..32691)
                     /locus_tag="TU257_000246"
     CDS             complement(31741..32691)
                     /locus_tag="TU257_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL0833311.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(32919..33083)
                     /locus_tag="TU257_000247"
     CDS             complement(32919..33083)
                     /locus_tag="TU257_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL0833312.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(33612..33869)
                     /locus_tag="TU257_000248"
     CDS             complement(33612..33869)
                     /locus_tag="TU257_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL0833313.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(34406..36445)
                     /locus_tag="TU257_000249"
     CDS             complement(34406..36445)
                     /locus_tag="TU257_000249"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL0833314.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(36811..37722)
                     /gene="glyQ"
                     /locus_tag="TU257_000250"
     CDS             complement(36811..37722)
                     /gene="glyQ"
                     /locus_tag="TU257_000250"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL0833315.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(38088..38621)
                     /locus_tag="TU257_000251"
     CDS             complement(38088..38621)
                     /locus_tag="TU257_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL0833316.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(38888..39112)
                     /locus_tag="TU257_000252"
                     /pseudo
     CDS             complement(38888..39112)
                     /locus_tag="TU257_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(39142..39981)
                     /locus_tag="TU257_000253"
     CDS             complement(39142..39981)
                     /locus_tag="TU257_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL0833317.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(40068..41216)
                     /gene="nagA"
                     /locus_tag="TU257_000254"
     CDS             complement(40068..41216)
                     /gene="nagA"
                     /locus_tag="TU257_000254"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL0833318.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(41333..42974)
                     /locus_tag="TU257_000255"
                     /pseudo
     CDS             complement(41333..42974)
                     /locus_tag="TU257_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            43165..43911
                     /locus_tag="TU257_000256"
     CDS             43165..43911
                     /locus_tag="TU257_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833319.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(44517..45359)
                     /locus_tag="TU257_000257"
     CDS             complement(44517..45359)
                     /locus_tag="TU257_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0833320.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            45491..46048
                     /locus_tag="TU257_000258"
     CDS             45491..46048
                     /locus_tag="TU257_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0833321.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(46459..47283)
                     /locus_tag="TU257_000259"
     CDS             complement(46459..47283)
                     /locus_tag="TU257_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0833322.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(47288..47902)
                     /locus_tag="TU257_000260"
     CDS             complement(47288..47902)
                     /locus_tag="TU257_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL0833323.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(48063..48935)
                     /locus_tag="TU257_000261"
     CDS             complement(48063..48935)
                     /locus_tag="TU257_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL0833324.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(49146..49631)
                     /locus_tag="TU257_000262"
                     /pseudo
     CDS             complement(49146..49631)
                     /locus_tag="TU257_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(49634..49900)
                     /locus_tag="TU257_000263"
                     /pseudo
     CDS             complement(49634..49900)
                     /locus_tag="TU257_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(49902..50834)
                     /locus_tag="TU257_000264"
     CDS             complement(49902..50834)
                     /locus_tag="TU257_000264"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL0833325.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(50844..51359)
                     /gene="lacB"
                     /locus_tag="TU257_000265"
     CDS             complement(50844..51359)
                     /gene="lacB"
                     /locus_tag="TU257_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL0833326.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(51375..51800)
                     /gene="lacA"
                     /locus_tag="TU257_000266"
     CDS             complement(51375..51800)
                     /gene="lacA"
                     /locus_tag="TU257_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL0833327.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            51936..52718
                     /locus_tag="TU257_000267"
     CDS             51936..52718
                     /locus_tag="TU257_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0833328.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(53134..53685)
                     /locus_tag="TU257_000268"
     CDS             complement(53134..53685)
                     /locus_tag="TU257_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0833329.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(53698..54648)
                     /locus_tag="TU257_000269"
     CDS             complement(53698..54648)
                     /locus_tag="TU257_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL0833330.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(55519..57750)
                     /locus_tag="TU257_000270"
     CDS             complement(55519..57750)
                     /locus_tag="TU257_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL0833331.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(57750..58184)
                     /locus_tag="TU257_000271"
     CDS             complement(57750..58184)
                     /locus_tag="TU257_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL0833332.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            58414..59451
                     /locus_tag="TU257_000272"
     CDS             58414..59451
                     /locus_tag="TU257_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0833333.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(59523..59873)
                     /gene="rbfA"
                     /locus_tag="TU257_000273"
     CDS             complement(59523..59873)
                     /gene="rbfA"
                     /locus_tag="TU257_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL0833334.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(60063..62933)
                     /gene="infB"
                     /locus_tag="TU257_000274"
     CDS             complement(60063..62933)
                     /gene="infB"
                     /locus_tag="TU257_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL0833335.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(62953..63255)
                     /locus_tag="TU257_000275"
     CDS             complement(62953..63255)
                     /locus_tag="TU257_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL0833336.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(63248..63544)
                     /locus_tag="TU257_000276"
     CDS             complement(63248..63544)
                     /locus_tag="TU257_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL0833337.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(63560..64714)
                     /gene="nusA"
                     /locus_tag="TU257_000277"
     CDS             complement(63560..64714)
                     /gene="nusA"
                     /locus_tag="TU257_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL0833338.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(64824..65306)
                     /gene="rimP"
                     /locus_tag="TU257_000278"
     CDS             complement(64824..65306)
                     /gene="rimP"
                     /locus_tag="TU257_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL0833339.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            complement(66687..66866)
                     /locus_tag="TU257_000279"
     CDS             complement(66687..66866)
                     /locus_tag="TU257_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0833340.1"
                     /translation="MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYVLPHEEVRSWE
                     VSIEEIVEEVLRELE"
BASE COUNT        19578 a        15875 c        12908 g        18568 t
ORIGIN      
        1 cagaatattt tagaaatact ataggttatt ttgaatcttc tgattgtttt gacagttaca
       61 agaaatccca gtgattaaca cggagacaag ccccagtaat tatcgattga agagggagct
      121 tttttcttga ttctccttaa gcaaatcagc aagcattggc ttatccaagc caaatgtcct
      181 tacaacaagc accggtagcc cacttcattt gacaaggggc ttgtcagcaa gcattgatca
      241 caaatcaggc tgagctgcat taagctcaag agagcttgcc atcagcctgt tggatcaagc
      301 gatactataa gcctattaac aaactggcta gacagagcat gaaggctgat tggtgctgcc
      361 tatttttaag gctaaaaaag atctaaagca tgcaggattg gcatgcctcg cctgaagcat
      421 tggtatcggt aagcgctaca atcgtatctt cctcatactg ctcacttcct tccagaacgt
      481 cctgtctgac gcgaacataa taaatggacg cacactttaa cttaaaggcg tgtatatagg
      541 cacggttgag atcacgtgtt gttgcttggt ctgtcataaa tagggttaag gaaattgcct
      601 gatcaacgtg cttttgagcc gctgctacga tattaataat aggctcaggc ccaacctcat
      661 aggcaccacg ctcgtaataa gcatagttat catcgcttat ctgataagca ggcacataaa
      721 tccttcctaa gtgcccctcc tttcgcacct caactggtgc aacaacaggc tgtaagctcg
      781 gcgtacatga ggacaagtag ctgatcgagc cggttggtgc aactgccatc aagtgagcat
      841 tggcaaggcc tgtctcttga atcgtcgcaa ctaattcctg ccaatcagcc acactaggca
      901 ctcgaagccc gtagcgctca agcaaggccg caaccttagc tgtcttaggc ttagcctctt
      961 ttgtcaaata gcgggcaaag tagctgccat ctgcataggt tgactgctca aagccagcaa
     1021 atgctccctt ttccttagct aattgactag aagccttaaa ggcataatag gccattgtgt
     1081 ggaaaaagag atcagtaaaa tctactgctt cagctgaatc ataaaagatg tgattggtcg
     1141 ccaaaaagcc atgtaaattc atcgcgccaa gaccaacagc atgattagca gcattcccct
     1201 tttcaacaga aggagcgcag ctgacgtctg aggcccttga cacatggtcc aaggccctaa
     1261 cactagttgc aatcaattgc tcaaagccaa ccgcatgctt catggcttca gcaatattaa
     1321 tagagccaag gttacagcaa atgtcctcgc cgatttgctt aaaggtcaaa tcctcttcaa
     1381 aggtgcttgc tgtgctgacc tgagcgattt cagagcaaag gtttgacatg acaatccgcc
     1441 ccttttgtgg gtgtggattg cgcttattaa ccgtatcatc aaacaagaga taagggtagc
     1501 cagattcaaa atgaagctct gcaataagct gaaagagctt acgggcactg atataggtct
     1561 ttttaatggc tgggttggcc actaggcggt catactcctc ggtaatggca atatctgaca
     1621 tgtccttgcc ataaactcgc ttaatgtcat agggagaaaa tagcgccatg tccttatttt
     1681 cccgcgccag ctgaaaggta atatcaggaa tgacaacgcc taacgccagt gacttgatac
     1741 ggattttttc gtctgcattt tctctcttcg tatctaaaaa ggtcagaatc tctgggtgat
     1801 gcacattgag gtaaaccgca cctgctccct gtctttgccc tagctgattg gcataggaaa
     1861 aggaatcctc cagtagcttc atcactggca caatgcctgt cgcttgattt tcaatgcctt
     1921 ttatgggaga gccaacctct cttagattgg ttaaacacaa agcaacgccg ccgcctcgtt
     1981 ttgagagctg caagctcgta ccaatcgcac gcgaaataga ttccatgttg tcttcgattc
     2041 gcagcaaata acaggaaata tattcgcctc gacgcttttt acctgcattt aaaaaggtag
     2101 gggtcgccgg ttgaaagcgc ccgctaagta tctgatcaat caaatcccgc accaaatcag
     2161 gatcaccatt agccaaaaac aaggcattca taacagcacg atcctcaaaa tgctctaggt
     2221 attgtgaccc atctagggtt ttaagcgcat aggactggta aaatttcatg gctcccatta
     2281 agctcaaaaa tgagaacttt tgctggtaag cgtaggtaaa ggcttcagtg atacattcag
     2341 ccgaataagc ctttaaaatc tcttgatcat aataatcatg cgccaccaaa taacgccatt
     2401 tctcctccaa actatcaaag gataggcttt gtgggtagac atgctcctct aaatagcgct
     2461 gaacagcttc cttatcactg tcaaagtgat aggtaccatc tgctcgttta aagcgtgtaa
     2521 gggcatttaa tgagaggtag gactcttttt gtgacattct tttttccttt cgttacaatg
     2581 tgtgatcgtt tttctatcat tagttataag gcttcatcac ctgctaaaat agcctgcacc
     2641 ttgatgacat ctctttgtgt ccccagcaat tcaaattggt gcaaaagcgg cacctgcaat
     2701 ttttgtgcaa tgattggtcc tgcaatggca aaggtatcac caaagttagt attgccagag
     2761 gaaataaccc ccttacagtg ccttcgattg ttagccttgt ttagaaaatg aatcacctgc
     2821 ttgggaacag ctcccttgct gtctgagcca ccagcagcat aggtagggac aatcaaaata
     2881 taatcctcat caactaatag aggctcacca gtgactggaa ttcttagagc tcttacatct
     2941 agcttttgca caaagcggtg agtgttgtta gatcgcgatg aaaaataaac aagcattacc
     3001 cttgcagcca tcttaaaact cccaatcatc atcaatggtt tcctcagtaa ctcccatcac
     3061 gtaagaagag ccatttcctg agaaaaagtc atggttctca tctgctcgcg ctgatagctg
     3121 agcaaatacc tcaggggaaa tacgtgtttc ctcctcagta aagggagaat cataccctag
     3181 attttgcaaa aattttccag cattatagac gctaaagcga atcgcatcgt cagcaagatc
     3241 aaagccgtca tacaattccc tcaggtaagc cttctccaaa tcaatcagct gataaagcag
     3301 atcaaacaca aaggccttca tctcagcctg cttttcagga cttagggctg ccaccttttg
     3361 ttgatacttg tagccactgt aataattgtg aatgacctta tctctcagga ttaagcgaat
     3421 aatatctgag gtattgggca ttttgcctct agctgacagg taaaaaggca ggtaaaagcc
     3481 accatatagc aaaaatcctg gcatcatagc tgctgcgacc ttagacttca gagggtcatc
     3541 accagtataa tacggaatca acacacgcgc tcgctcctgt aagctctctg ttgacaccac
     3601 ccaatcgtgg gcctcctcga tctgctgact gctgcacagg gtcgaaaaga ttgtcccata
     3661 ggacctagcg tgaatagcaa ccataaaggc aaaattagta taaatcacct gctcatgatc
     3721 ggtcaaagaa tgttgaattt gtgccacatc tccaactgtt gcttgaaccg tatctagcaa
     3781 ggtcaagccg gtataggttc ttgtgatgag cctttgccaa tcctccccca aagaacgcca
     3841 agaattaagg tcattagaaa caggaacctt ctcaggcagc caaaaatttt gcgtcacacg
     3901 gttccagacc tccaggtcct tgtcgtcatt aagctgattc caattgacag agcgcaaact
     3961 ttttttggtt tgagacaagg catagtcaat gggtgactgt gatcggtcgt aataatattg
     4021 ggtcatgttt tctccttcaa gcttgatagt cgcaatatca atccttcagc tgccaagcct
     4081 tctacagctt taggactagg gaagactgct aagtgccaca tttagacaac acaaaaagac
     4141 ttgctctaaa gggcaatcct acaggctaat gataatttct tgctgatgat ccctaaccag
     4201 tcagcaactg ctttgtaagc aaggctaagc ccgctttttt ccccggctga attaagtata
     4261 cttaattctt atgtttgtta taataacaca atatatagtg ctttgcaatc tttttgatac
     4321 aatatataga ttaatttatg aaaaagaaat cataaaagga gctagcagca ccttaacgaa
     4381 agccctgtct gtatgctcac caatccctca tctgccaact tgcttttcaa ataagatcaa
     4441 tacatatcaa ttcacacccc catgaaggga gcgactagag cgtgagataa agaaacaaaa
     4501 atgatgtatt ttcaatactc agagctttca ctgctgttat tgcctattag gctgctagac
     4561 tagtgcttct ttcttgttca aagtttacaa agctcccaca agaagtctag gtctcttgtc
     4621 tttttaagac actaaaaatc ccgtatgctc ctgctaatca atctattagc aagacccata
     4681 cgggatattg tcatctaaaa gcccaatcag ccaataatcg taccatttgg cactgccgga
     4741 tcaaccgtca gcactgtcag cttgccatca tgttctgctg acaaaagcat gccctgactg
     4801 atatattttt tcatcatttt tcgcggcttg aggttggcaa caatttgcac cttcttgcca
     4861 acgagctctt gttcatttgg gtaataggct gcaatacctg ataagatttg acgatcagag
     4921 ccatcacctg catctaatct aaagcgcagc agtttttcag agccttcaac tcgtgacacc
     4981 tctttgacct ctgccacacg aatctcaact gcatcaaaag cctcaaaagt aatcgtgtcc
     5041 ttttcagact taagggctac cttttcagga tcccagtctg cttcttgtgg cttagctatg
     5101 ctcattgtca tttgctcttt gatatagtca atctctgctt ccatatcaag acgagggaag
     5161 attggctctc ctttggcaac aaccgtcaca cctgtcggaa gatctgctaa atcaagctct
     5221 tccagatgat atttggcacc gagacctagc tgctccataa tagcagctga ggttgtcatc
     5281 ataaatggct gaatcaaatg agccaccacg cgcagacttg cagctaaatg tgccatcaca
     5341 ctggctagct gctccttact atcagctgct ttggcaagca cccaaggagc agtttcatca
     5401 atgtatttgt tcgtgcgtga aataatcgtc catacggcct ccaaggcacg tgggtaatca
     5461 acagcctcca tttgcttgtg gtattcggaa atatgatcag ccacaacctg ctccagatcc
     5521 gcatcaaaag ctgtaacgtt tctgacataa gcaggaaccc tgccgtcaaa gtatttatta
     5581 atcatggcaa ctgtacgatt caaaaggtta ccaaggtcat tagccagctc ataattgata
     5641 cgaccaacat aatcctctgg ggtaaaggta ccatcagagc caaccggcaa ggaacgcatg
     5701 aggtaataac gcagaggatc aagaccaaag cgctcaacca gcatttcagg atagatcaca
     5761 ttcccctttg atttagacat tttaccgtcc ttcatgacaa accagccatg agcaatcaaa
     5821 cgctctggca ttggtaaatc aagcatcatc aacaaaattg gccaataaat gctgtggaaa
     5881 cgcaaaatat ccttaccaac catatggaaa accctaccac tccagaactt atcgaagtta
     5941 gcatgatcct tctgaccgta gcctagtgct gttgcatagt ttaagagagc atcgatccag
     6001 acataaacaa cgtgtttagg atttgacggc acagggaccc cccaggtaaa ggttgttcgg
     6061 ctaaccgcta gatcctccag acctggctcg atgaagtttt taagcatttc attcatacga
     6121 ccgtccggct gaataaaatc aggctgagcc ttaaagaagg caaccaatct atccgcatac
     6181 ttgctcaggc gcaaaaaata agattcttca gagacccatt cgacctcatg ccctgatggt
     6241 gccacaccac caatgacctt gccagcttca tcgcgataaa cctcagctaa ctgactttct
     6301 gtaaaaaatt cctcatctga aacagaatac cagcctgaat aggtccctaa ataaatatca
     6361 tcctgcgcca gcaacctctc aaatacagca gcaaccacct cctcatgata gtcgccagtg
     6421 gtgcggataa acttatcata agagatatca aggagcttcc atagtgcctt gacttcctca
     6481 gccatgccat caacataagc ttgaggggat aagccggctt cttgtgcctt atcctgaatc
     6541 ttttgaccat gctcatcaag accagtcaaa taaaaaacgt cataacccaa catacgctta
     6601 tagcgagcaa gaacatcaca ggcaatcgta gtataggcag agccaatatg aagcttccct
     6661 gacgggtagt aaatcggtgt tgtaatataa aatggttttt tcttagtcat cttacgtcct
     6721 ttcaaggcta atgaaacctt tgtaatcagg gactagggca atacccattc ccaagctgag
     6781 tcctgtcagc tatcaactga cattatacca taattttagc ataaaaaaat gatcactcag
     6841 cctattaact gatacctccc ccataataga caatgacaaa caagcagtca tcaaaaatta
     6901 taggaggagg atatcaatta gtagacttca atcatttttc aatgatacct gatgatggta
     6961 aaattcctgt gccaagaggt agttcacgta gcacaatggg atcagcatgg gagataaggc
     7021 atactcacca taggatagtg ataaaagagt agaacagacc actccaaggg caaaggagag
     7081 gataataatc aaggtattgc gaccaatatg gactagctct ttgttgttct catatagtcc
     7141 ctttgtcaat aggtaggcag catttttaat attaccagtc atcatcacat tggcatagct
     7201 cgcaccgcgc aaggttttaa aggtatctac ctgaatcgaa gcaaaaaaag ctagagctga
     7261 aaccgtaaaa aatgacgaca ataagggtgt gaggattgct gtcacaagag caatcagggt
     7321 caagataaag ctagacaaaa ggtaccaatg cagaccatgc ttattggccc agcagtgcat
     7381 aaagtaggta aaggcctgcc caatcataaa aacaatgata ggcaataaaa attgcagggc
     7441 ttggtcaaac tggcgctcag acagacgaat cgcaaaggat aagagattgc ctgtctgaac
     7501 ccctgcaaag cgcctgcctt gcgtcatgta ggtaaaggca ttgacataac cactgataaa
     7561 gcaaagcatc atggcgcacc ttaagccctc atatacctga tacgtttttc gtttcctctt
     7621 tgacatactt gccttcctta atgtgattcc aaaagaaaaa tactgacaaa cagtatttga
     7681 tgtgattatt aggaggataa gctaagctca attgcccttg atcacagata gtcaccaaag
     7741 caagttctgc agctagactc ggtaagtccc ccaaatacag ctttagtata gcataggcag
     7801 tctcttttat caagatgctt tgcaggatca actagcacca taagactaac cattagccaa
     7861 aaagtactca ccctctatga ggaccagcag gtaaacctga taaaaaaact aaaaagccac
     7921 catttctgat gacttcttag tcggcctctt caacaacttg tagcttacac aagctatagc
     7981 gctaaggaca gcctttcatt ggagcacaac attagtcttc cttgcgtttt gttgacacaa
     8041 caaccacacc tgcacttgcc atcactgcaa gagctgccgc tgtgaagaat ggatgtgtcg
     8101 cttcacctgt tgatggaagc ttcttagctt cttgcttagg tgctggtttc ttctcttcct
     8161 tcttagcttc aggttttggt tctggcttag gctcaggttt tggttctggt ttaggctcag
     8221 gtttaacctc ttcatacaca taaaccacac gaagatcgcc ttctagggtt gtaccagttt
     8281 cgctaggtga gccctcttga agcttcttga acttgtagac cttaccatct ttttcaatct
     8341 tatcaagacg aagtgaggta gtatcgtacg cttcacccgg caagccttgt gataccgcaa
     8401 cagtttcacc taaaacatta ccttctgtat ccacataaga tacaagaaca ttagcattaa
     8461 acggaacaaa ttcccaatca ccaattaaag taatatctcc atcacctggt gctgtatagc
     8521 cctctgtaag tttagtttca ccatcatttg tgtaacgtga ccaaccagta aatctccact
     8581 caccagttgc agttctgaca ttttagcaac atcaagaagc tcctgtggta aagtcatacc
     8641 ttgcttgcta ccgaaaatgt agataactgt actcttctct ttacgaagag cttcattagc
     8701 tgcttcttct tcggcacgtt ttgatctttc tgcttctgcc ttaaccgcta tagtttgttc
     8761 agcctcagct aagattttgt taatatcgtc aacttgaatt aaatttgaat cgttaatttt
     8821 cgattcaaaa cctgcgattg ttgaagccaa ttccggatgc tgttgtttaa gagtagttag
     8881 acgagctgta gcctcagctt tagttgcata cttctgccct ctcattgtta cctgtgccga
     8941 tacagaagct gtaccaacta acaaggtgca gaatactgaa gctagtccga aagccgactt
     9001 acgaagatag tacttcattt ctttttttgc catttttatt cccctttaaa tataatggac
     9061 ataatgtctc ctaattatca atgacagata attacacttt tattataaaa ggtattttct
     9121 gtttagtcaa gagaaaactg tttcttttac atttctgtta ttttacagtt atatgtcaca
     9181 tctgatttgg tttaattttt ctgaaaaacc agtagataag gcattttaag cattttttga
     9241 tgataagata atatcacaaa acattaatta tatgacaatt attgttttta attattagaa
     9301 tttttaatca aaactatcct gcaatcagct gtttagccat tttaaaaggc aaacaaaaac
     9361 catgccacat tgcaatgaca tggttttctt caagaaagga gcgagctttg gtttggtact
     9421 ttctacaact gatctccaat agcagctgct cctcgttagt ccctgagcca caggtgactg
     9481 agctttcctg cggctactct gatagtacca gctactctta caactgcata aagcagtggc
     9541 tgccagccaa gctaaagcta aacaatatta ctctgttata gcttggtctg ctgacgagct
     9601 ctcaatggtc atgtgattga ggtagttgtc atcagccagc tgagccttaa actggtctcc
     9661 gacctttagg aaaggcagac ggtcactagt ttcactgctt gccttgattt tataaatctg
     9721 acccttggag gaaatgtaat aaaccgttgt tcctgagata atctggctgg ccaattgctc
     9781 cacctgccca gtaatcatct tgaccttctg atcattggtg tctgacactg acagcgagct
     9841 tgtgtcctta tctgtgaatt gtgagattaa ggtctgaatg tcattattca ctgttacctg
     9901 ctgataatcc tctgcatcaa ccaaggcata ggattttatc agaccagccc cgtccttcaa
     9961 tgagataagg taataagcct tgtcatttaa cttgactagg gttggtgcag ttgcagtgta
    10021 tttcttctct tgaacttcgc cctcggctga tttcatggca gaggcctctg ttgcagaagg
    10081 cagcttatag ttagtgacct ctctggtacg catgttaacc aaaataaagc cgagatttga
    10141 cgaatcagct gttgctgagg tgattcctgt atagaggtaa atgtctgagc cgatggtaat
    10201 gtagttatag ctgtctgttg tttgcttgac atctgtctgg ctaaagacag tgttccaata
    10261 gcccttttga taggtgtaat agtcattaac cctctccaaa acattgtcag cagaatagac
    10321 acgatcaacc cattttggaa cgtcctttag ctcatagtat tgagacttgc cgctaaccgc
    10381 gtctaacagg atcacacccg tcggctcctg agaggacagg ccaaattttg gggcgtaggt
    10441 tgttgcgaca tagtaagggt taccatcgtc atcaacctca aatgacgggt ctgaaaaaat
    10501 ggtcatcggg tactggaagc gcaaatgcct catggtgtct ctaaacataa attccgaatg
    10561 agaatacttc ataggctgat ttaacttgac tagctctgcc ttaccagttg tctgattgac
    10621 cttgacataa tagccaatgc cgtccttacg attggttagc catttccaga aggatttgta
    10681 ctccaaggga gaaacacgat aagggagctt gccgatcgta atctgacggt actcatcaga
    10741 aataccaaac tgcgatacct tatcaatggt cccaagataa gtatctccaa tcttttcagc
    10801 cgaatctcga tccagcaatg ccaaggctga cagatcagtg tctggaaaat ccttgttaaa
    10861 atcagcgtcc tttaccttaa tcacatgagc ataggactta gcacgaaaca ttctagtatt
    10921 aacagctaac agcaaggaca agccagcaat gataacagca agggcaagac caagccactt
    10981 tatgccaccg gttaattgct tgagtgaaag acctgaggtc acgtccttgc ggccagactt
    11041 ttgcgtgaaa aagctggtca ctgttttttt caacccaaac aaggacagga taaaaagact
    11101 caccatcgcc aagataagcg caagaatcac gaaaaaccaa aattctaagc tcatcacgtt
    11161 cattggcggc aaataaatcc agtaaaagcc agccaggatc aagctgtcta agccaatcag
    11221 caccaaagaa gcaacttttt ttgtcatact aatctcctcg tcacacccta aggctatcag
    11281 gggtattcaa tatcttctca ccgctattgt accacatttc ccctcaaaag atgacatctc
    11341 agccagacat ttttatcagc tcttagagca cctcagctag aatgatcaat acagctgaca
    11401 ggctacgctc atagagcttg cttagtactt cttttgacgc tggcaagagc ctgctgctcc
    11461 aagactgagc aagcctagca ggactagatt gaccgctgct tgctcacccg ttgatggtag
    11521 gacttgggct tttttaactg cttgtgctgt tagggcagag ctagtgattg atgagccggt
    11581 ataatgagtc aagcctccag cctgatgttc tagctgaggc tgcttagctt tgataacctc
    11641 aaaggtaagc tcaatcacgc cattatgtga tacctctaga cctccttgac cgattagctg
    11701 atagccctcc ggtagctcaa cgaggacctc atagcttcct tgtcgcagtg ttttaccata
    11761 ggcacttgga acatagagag acggagctag agaaatcaac tgaccatttg ctgctttcag
    11821 gctgaccctg ctgccttctg gcaagacttg gttaaacaag agccaaacag aagccacaat
    11881 aggccttgtc atctcaaagg caactgaagc aagccttgta tccgcatcta gactaaagct
    11941 aaccaagttg tcagacctta gctcaaacag atgattatca taagccaaga gctcaacggt
    12001 gtagcgtcca aatggcaata tcaagctatt agctgagcta ttgaaatagt ccaactgctc
    12061 gattggcttg ccctgctcat cacgaataag ataagtaaag gctggctctt ttttgttctc
    12121 aagcacatca agtgccaagg caacggacac tactcccttg tctggtccta cagctcgcaa
    12181 agcagctaag ctcatataag caatctgacc tgcctcgtct tccactagat aataataatc
    12241 tgcttctgca acgccttcaa ccttaggaat ggtgtaggtg ccgtctgcat tttgagcaat
    12301 catcacctta ttatccttga atctgatcag ctgatcttcg acagttagat caaacttgcg
    12361 tccatctttc ttgacaaggt agaagacctc ttctctaaca atacctattg gactttgtcc
    12421 cttgcttggt cccggacgaa agacctcagt agcaccatca gcttggaagc tagctggcgt
    12481 aatgactggc ttttgatggc taactgtcac cgcataggcc tctgcttgag gcataccatt
    12541 agcgtctaga taagaaacaa catagcgata atgtcctgac atcaccctag ctcctgaggc
    12601 tcttgtgcca taccaagcgg tgctgtcaac attagccacg cttgcacctg gttggctaga
    12661 ccagattggg cttgtcatag ctgtatcctc ctgggcaaag accgttacct ttagatcttg
    12721 atatacttga tgtggcaagc ccttgaatgc cacaaaatcc ttgtttccat catcattcgg
    12781 cgagatgaca gcagtttgac ctaatttagc caaacgactc tgtggtctat tgcggctaat
    12841 aatgagaagc tctgcttcat ttgtcaccag tcctgtatct gcagcagtca tgttgaggtt
    12901 atcactgtag ctcagctgat gctgagcatt aatatcagtt agggtcaatg ccagctcagc
    12961 ctgaccgatt ttttctggca agtgatttcc cagcttagca atggcaacat tgcctgcaaa
    13021 atcctcgacc atgtaataaa aatcaccaag cgccacctga tcaactggca ggacaaaaga
    13081 gccatctgct aagcgctcaa caaactgctt attgtctgat acggtcacat actttaagcc
    13141 atcattaatg gtaatcgtat aaggcttgtc atcctttgtt tccaagtaaa aaacactatc
    13201 tcgaagaaca ccagcctgac cgcgatcaag ccactgagac ggtctgaagc gatgggtcac
    13261 agggttatag cttgctgttc ctagctccgg cgtttgacga tccacaatca cctcaaagac
    13321 catttcttga cgtttcgctc ctaccacatc tggataataa gaaaccacat aatggtattt
    13381 gccatctggt aggtcagctc cggtcagcga tttaccacta aagcctgttt ctaacagcgt
    13441 tgttgacttg gcaaagcgaa tatcactgtt aaagttttta tccccttgaa gggctgatgg
    13501 gctcgtccag agcaactcct tacggtctgt atctgttccc ttatagaccc tggcttgcag
    13561 gccttggtat ttacgtaaga acaccccttt gaaggcagca aagtcttgat tgttgtcgcc
    13621 atttggagag atagccaaca caggatagcc aactgcattt cgctccaaca caaatttacc
    13681 gtctttatta cgaaaggttc ctagtgtgtg caagccattg tcagcaatag tagtcataga
    13741 gacattggta tctgtaccaa cagtcaccag cccagtaaaa tgattgccga cataaatctc
    13801 gtcctttagc cctgagctgt caaaataaaa gccagttttt ccttgagcct ttagctcata
    13861 aatagaggct tcaacaacag gtaggttttc aaaggctccc ttaaagccaa caaatggaat
    13921 gttgatgtta tccttgtgct cgtccttgct atccacaaag cgaacaaagc cctctagata
    13981 atagccattt ggcatttgct tagagagttc ctctgtaaag tttgaggcat ctagggtaat
    14041 ggtaatggtc ttgtgtcctt gagcaggtac gtcaacctgt tctccctgat aggttttcag
    14101 agatcttgaa cgtaaggcaa aacgtccttc cttagtatcc acctgatcag tcaacaattc
    14161 tgtctggtag cgcagcgact tagcctgatt agacaagtta tggattgtca cctcaaagct
    14221 tatctgatca gtcacatttc caagagaaat actgccatag ttgtctttac ctgtcaggta
    14281 cagaccactg gttaccgcgg tctctatatt caagagccct gctccctgct ggcgtggcga
    14341 tgtggtggta ttggtcttag ggttgatgtg gatctgagca ttactcatca gtatattttt
    14401 gaccagatct gctagcttat ccttggcaag ctgtggttga agcgcttcta gatattgctt
    14461 gaccaaaagg cttgcccctg caatgtgtgg ggttgccata ctagttcctg actggctgcc
    14521 atagtgatca tcgttgaagg tcgagtaaat atctccacct ggagcagtga tgtcaggctt
    14581 caaatagcca tctgaggtca agccccagtt agagaaatag ttcatctcat ttcccttttg
    14641 gctaatggcc ttagagacct cagcatcaaa ggtcagagtg cctgttccat tgccatttaa
    14701 agcagccatt gccatgccaa attcatgaga gataaaggca gatggcagca ccatcccctt
    14761 tgaactcaga cgcatggtgc ggttagcctt gcctggctca ttgttaaaaa tcaagacccc
    14821 agctgccccg tactgcttgg cctctgctat aatatcgtcg tatttccgat taggatcacg
    14881 ctgcaccaag acaatcttgc cactcacttc gcgttcttgg tagccttctt ttgtcaaagc
    14941 tttgacataa acaaatgagt atggtacatc aaagccaaga ctagtcttaa tgtccttgaa
    15001 atcaacagat tccaaataga tagcctttcc atgatttaag tcagccctat ctttcaagcc
    15061 ctccaccgtc atcagacgct ctataatcac tttgttatta atagacgcaa ctgaggtagg
    15121 agtccggcct gctgatggag cccccactaa gccataatca ggatttgtca ccaacgggtc
    15181 tgcatgatct gacccaaagg cacgctcatt acctgcagca acgaccacag agacaccagc
    15241 ctgccttgcc ttttcgatag ctgccatcag ggcacgattc ccattcaatt gagacccatt
    15301 ggccgagccc agacttaaat taatcacatc agcgcccaat gccacagcat cttcgatggc
    15361 tttaataaat aaggggtccc cagttcccat caaatcatgg gtaaaaaccc gcataaacat
    15421 gacctgagcc tcaggagcaa tgcctaaaaa gcgttcgcca gctgctgccg ccttgagccc
    15481 atttccagct gcaatgcctg tcacatgcat gccatgcgat tcatatttgc tgtcatcatc
    15541 tgtatcttgc cagtcaatga tagttcctcc tgatgtgtca tcaagcttga tgaccgtttc
    15601 ctgaggtgcc tctattgact gcggacggtt cctcctaata tcaatctgct gcacaatcac
    15661 atcaaaatcc aagtcgtcaa ggccctcaaa cggatcgtcc tttatctcct ttaccttatc
    15721 attgttttcc acatagttgt gggcaaagac taccttatcg cttagccaga caccgtactg
    15781 aatgcctgct gcttttttgc gctggtcaat atctgccttt gatgtaaact tagcagctgc
    15841 tggatttgta atgcgcatgg catggtgact agcgtcaata ccagtatcaa taacagcaat
    15901 aaccttacct tgacccttat agcctctatt ccaagctcct tctgttttta tccagcggtg
    15961 agtatccata tttactggag gtagctcgcg cgattcttct tgctgcttga ctgattggtt
    16021 agattccgtt agcgcttcca tttcggaaga aactaatcca gtcgccattg cctcctctgt
    16081 cttttcctct gctttacttg actggctgtc gatgtcctga gcattaacag cagctccctc
    16141 actagcctga gagacagaca atacctccct tgattcttga tgttgtcctg ctgacacgtg
    16201 agctgagcta actccctgct cctcagccac aactgatccc atccctgtca gaaaaaggat
    16261 tccgatcaac acagaaacca ttcctgattt atatttcctc agtgagaagc gttctttttt
    16321 ctccacttga tgtcctccta gatttattaa aaaaggttat tttaaacaaa tgattcattt
    16381 atgttttaat caataatgtc taagctattt aaccattttt taatcacaaa agcaataaga
    16441 ctagaagctc tcagtttatg tcatttttta atcattcaac tcactgaaat gaggcctctc
    16501 agaacctgtc tcatcaacag ataaggctaa actcagccgc tagacttcaa aaatgtcaca
    16561 ccatttttag acattacctg tcctcatacc tataacagaa ccaagcttcc acagtcgcct
    16621 tggccttatt tttttgttac aatataggtt aagattatca tttagaaagc gaagaaaaat
    16681 gaaactcatc tcatggaaca ttgattcttt aaatgctgcg ctcactggtg aatctcctag
    16741 agccctctta tcacgcgctg tacttgatac tctcgtggca caggacgctg atattattgc
    16801 aattcaagag acaaagctat ctgccaaagg ccctaccaaa aagcaccttg agagcttgct
    16861 tggctacttt cctaatcatc tcaatgtttg gcgttcatct gttgagcccg ccagaaaagg
    16921 ctatgccgga accatgttcc tctataaaaa agagctcaat cccattgtca cattcccaga
    16981 tatcggagct cctaccacta tggacgctga agggcgtatc atcaccctag aatttaacga
    17041 tttctttgtc acacaggtct acaccccaaa tgccggtgat gggcttagac gcttggaaga
    17101 gcgccagctc tgggaccaaa aatatgccga ctacctagcc cagctcgatg cccaaaagcc
    17161 tgttttggct actggtgatt acaacgttgc ccacaaggaa atcgacctgg ctaacccagc
    17221 tagcaaccac cgctctccgg gctttacaga tgaggagcgg cttggcttta cgaacctgct
    17281 taaccgaggg tttacagata cctttcgctt tattcatggc gatattccaa acgtttatag
    17341 ctggtgggca cagcgcagca agaccagtaa attgaacaat accggctgga gaattgatta
    17401 ctggctcacg tcaaatcggt tgattgataa ggttagtcgc tcagagatga tttcctcagg
    17461 agaacgtcag gatcacacac cgattttatt agaaattgat ctatagacta gaagcattcg
    17521 gacaaatcaa cccagacatt aaaaaaaaat ggctctgcaa gagaaccgtt tttttaatcg
    17581 cttaaagacc tagatcctta taggctgttc gataccctac ctgcaagacc tgattatcct
    17641 gtaagaggat cggccgctta atcagcatgc catctgttgc caaaagctcc gctgcctcct
    17701 caacgctcag tgaattaacc ttatctttaa gcccaagctc acgataacgc ataccactgg
    17761 tattgaaaaa gcttttgagg ctataatctg aatgctctag ccattgtttc agctgctcag
    17821 ctttaggggg attggcctta atatcaatga tatcaacctc agaaaccagg gtctttagct
    17881 cagcaagggc tttttgacag gtactacact ttgggtattg gtaaatggta atcattagct
    17941 actccttatt aacactaatt tgctcgtgcc tgagcaacca ggccttcttt tcaagtcctc
    18001 cagcatagcc aatcaagcga ccatcagcag ccagtacacg atgacaggga ataaaaatac
    18061 ttaaaggatt acgtcctatg gcaccaccaa cagcctgagc cgaacgacac tgcaggcgct
    18121 tggcaagctc accatagctc aaggtctctc cccatcttat cgtctgcaat tctcgccaga
    18181 cagctcgctg aaaatcagta ccctgtggag ataagcaatc aagcatggga tagggcttcc
    18241 tctcaaagta agcgtcaagc cacaaacagg ctctttttaa cagggcatgc tgctcctgcc
    18301 agatgggctg cactttaatc ccagcctgaa aatacctttg accttcaaac caggctccta
    18361 tcaaagcaac atcagtcgca accaaggata tttttcctaa gggcgattga tacacacact
    18421 cgtacaatgg caagatctga cctccccaca taatagctta ttcccttgac tatttattat
    18481 aagaaaaagc ctagctaaag gcaagaagga gccctctgac accacaacaa acgcatgaaa
    18541 aaacaatagc ggctctttca atgctgccat acaatcgtta gtgtcaaaag tcgcttacta
    18601 tacagctgcc ccccttgaaa aacgaagctg gaaagacaca acatgctaaa gctgtttcac
    18661 gcgctggtgc ctgattagat gttcttctaa ttaaaggcca atgttctgat taaaaagtca
    18721 tttcatgcgc tgatacctac tcaaataaaa acacatagcg tggggctaga ccaatccctc
    18781 acaagtcatc aatagttcgt ctatgagcta cactttatca cattgggata ggcagacata
    18841 tttgccggct cagttgtact tgcctgatag ctaaccaaaa gcccgataag ctttttccga
    18901 tcctatatca atagctgtag cggctatcct cgctaatctc ctgataagcg gctctttcat
    18961 ggcttttctt aattttttga taggctaagc gctcgccatc aattggtacc ttgccacagt
    19021 aaacaaagcc taacttttca atgatatgcc gcatgacctg attatgctca tgagtatcta
    19081 tccgaaaatc tggtccatgc tgcccctcaa tgagcccttg caaaaaggtc tgagcaattc
    19141 cctgaccagt cctatcactc agcaccgcca cacgatgaaa ggtcacataa cggtggtgat
    19201 tatgctgcca cctgccatca taaatcttgt cgtaggcgtc ctcttggcca tcaataacag
    19261 ccgcataagc aacaatctgc ccctcaagca aagccacata gccctgccct tgcaacacat
    19321 cagcagcaat atcctgataa gcaggatacc catctgcttt ctgccattgg ctggagcctg
    19381 attgggctaa ggcagactta gctgaattga tcactgtcat gatctgacta agctcattag
    19441 gaaaagcaag tctaatctcc atcgttcaca ctcacaatct attctgattt gatgatgcta
    19501 tgctaccgca aaaagcctta caccttgtca ctctgctagg gacacctcat agcggtatgc
    19561 ctgcttctca tctcagctga gtatagcaca atagtcatca tttgacaaaa agcctcttca
    19621 aggattgcca gcaatcatgc tataataaag taaatcacaa aggagaacca ttatgattaa
    19681 agaattttgt gctgaaaacc taaccatgct aaaccaattg accagccagt cggtcaatcg
    19741 tgttgagctc tgcgacaatc ttgcagtcgg tggcaccaca ccctcttatg gtgtcatcaa
    19801 ggaagcctgc gacctcctac atgacaagca gattagtgtc gcaacaatga tccgcccaag
    19861 aggaggtgat tttgtctata acgaccttga attgcgtgct atggaagcag atatcttaaa
    19921 ggctatcgaa gcaggaactg atgccttggt cataggctta ctcactaagg acaaccagct
    19981 tgacaccgat gctatcgaac agctcctacc agctacacaa ggactccctc tggtttttca
    20041 catggccttt gacctgattg ctcgcgacca acaaatcgca agcctagagc agctcattga
    20101 ctatggcttt gtacgaatcc tgcttcatgg ctcaagcgat accagatcca tctatgaaaa
    20161 cattgaccat atcaagcagt tagtcaaggc tgctcagcac cgaatcgaaa tcatgattgg
    20221 tggaggtgtc acagctgata actgccaaga gctaagtcaa ctaacaggaa cagctattgt
    20281 gcatggcaca aaaatcatct aactatcagc tcaaataaag gaaaagtcac tccctacaag
    20341 gaggtaaata atagcagccc ttctcgttga aggccatacc tgagccctta gactaggctc
    20401 ctagcaaact aatagtatag gaccttcgct gcctttacat caaaaaggct gccgtccaga
    20461 aaaagagaaa gccacacatt gatagaaaac catagctggc tctactacta tcagtatcta
    20521 tcatcagctt ctgagctgcc taaaagtttc ggtgatcatt aacaagtaca gactatttgt
    20581 ttctaaatta gatcataaaa cagacaatta taggaagcga caagtgaatc attattcatt
    20641 ttttattgat tactatgata ctataagtaa ggatagcgct ttctttttgt ctttgctttg
    20701 cctgactatt aggctctaga tttatttttt accatactaa tataagaatc ggaataaata
    20761 atgacaacaa ggtattttta taagctattg ctaacgatgt tgacactagc attaggagga
    20821 ttttccctat ctgcttgcca ctccaagatt agtaagccct atcaagtcgc tatttttgac
    20881 aaggatcatg ttaggacctt tatggaaaaa gctgacagtc tggtgcctgt tgagaccatc
    20941 tctcgaacac agcacaagct atttgagcga gaaagcttta agcaggccaa gcaagggtat
    21001 tttgcaaaga caagagaagg aaatgacctc aaggttctgt taactcacat tgatcaagca
    21061 agcctagaag aaaaagtcct tcatgctgat ggcaatgacg cctacacctc tacaactgat
    21121 ggtgattact tttacacaac agctgtcttt gccgatcgta ttgactgcta caagtatgac
    21181 cgccacttga aaaaacaggc tcacaagtct attctaaatc aagacaccat taatgccagc
    21241 aatcagtttc tggtgattga tgacgctctg tacctgcttg tcagcgctgt agacatcaag
    21301 agtcagcagc ccaaaactga gctatggaaa atggacaaat cctttactat cactgatcgg
    21361 atagatctgg acgaaagcac tgcctatctg cgcatggtca acgtcggacg aaccctttac
    21421 attacccagg ctgctgatgg cattttagaa actggagaac ctagacctgg taacaaggtg
    21481 atgacctatg acttagatag cggtcaaaag tcctatctca tgcttcatgt caatagtcct
    21541 agagccattt accaccatgc caaaaccaat gagcttatca tcgaaaatga tcagcattat
    21601 aatcctgact ttgcatggac catctaccag ctagataccg gagaggagag aaccattcgc
    21661 tttgaggagc tagccggtca ggagacaagc tctccctact ttatgatgac ctcaagcaac
    21721 tactacttcc tctttccaaa aaggctttac cgatacgatt gtagtaacca tcagatgacc
    21781 tgcatcaacc tagatcagta cggagtgacg cacgcccatg ccttgatcgc taagcccaca
    21841 ccataaatca caacaggcct aatcaccact cattcatcta caccccaatg cttagacaaa
    21901 gcagtgtact gacccccaaa agttggacac gacatattag tgaaaggatt tagttctgta
    21961 ttgcacaggg ctaagtcctt tcactaatat gtcgtgtcca acttttgggg gtcagtacac
    22021 tttgggaaag tatgtatgaa tctccagaaa aaatacctta tcaactacct ctatatgaca
    22081 agtatgaggg aaataatagt ttatttagag ataatgcctc accaaatttt agggcggatg
    22141 tcaaagatat tacagctact ttagtggctg ttttaagtaa tggttatcca accgggaaaa
    22201 gcagtttttg taaagactac tgtcccgatg aaatcagggc aagacaatta acccaattag
    22261 ctatttggta ttttacagat ggtatttctg aagaaacgtt gaaatcaaat tatagtctaa
    22321 atgatcttga atttcaagga ttaaagtatt taatacaggc tggcaaaact gctgggacta
    22381 gtaacaatcg aactttagat atctatatat ctaaagatag aaattcaaaa tttcaaaatc
    22441 ttttaggttc taccttagta gttaaaactc cagaaaacaa agagaactgt caatgtacta
    22501 aaatttatat agaagaaaat ggaaaagatg gttattatct ttacatctat gaggatacga
    22561 ataaaaacga taaatatgac aaaaacaaag ataaactact acagaaaaaa tacataaaaa
    22621 atgggaaaga cggcaagcct ggcctaaatg gtcaacgtgg gcctcagggc gaacctggga
    22681 aacaaggacc acaaggtcct agaggtgata aaggggaaac cggagaaaaa ggacaagatg
    22741 gtaaaccggg caaacaaggt gatcgtggtc cggctggacc tcaggggcct agaggtgaca
    22801 aaggggaaac tggagaaaaa ggagaccctg gacgtaatgg taaagacggt aaaccaggtg
    22861 aaaaagggga tcctgggcaa caaggcattc ctgggcctaa gggtgatcct ggaaaagatg
    22921 gagaaaaagg tgaacgtggg gagcaaggac ctcgtggaga aaatcccact cctaccccag
    22981 atccaatgcc acaaccaatg cctgaccctg cacctaaacc agaatccaag ccagaaccta
    23041 agccgatacc tcaaccagag gttaagcctc agccagagac aaaacctcaa caaccaaaca
    23101 agccatcaac cattactagc caacctagcg gcaaagcact accaaaaaca aacgacacag
    23161 gcagcttgat aacagtattg ggaacaggct tgctctctct tcttggactg ggcttcttaa
    23221 ctagacgcaa aagaaaacaa taattaaagc actatctata gctttttaat cattggctat
    23281 caaacaaatc acaaaaaagc ttatcgtttt actcctaacg ataagctttt tcgtattctc
    23341 tattacttgg tcccaatact atttttccag ctttaggctg gttttgttaa tccaaaataa
    23401 tatcagacaa tttccgtttt aattaaaaaa aaaaaaaaaa cgaaactgcg gaagctaatt
    23461 atcagaaaat gattcacagc ttagagtcac catgttaagc tattctacgg agaagaaagg
    23521 tttgggaatg actatttcta aactcaaagg agagaaacat gagaaaaaca atgaagaaga
    23581 tgctagcagc ctcgacagtc tgcatcatca tgtcgggcag ctttatcgga ggcgcggcaa
    23641 gagtactggc agagcagtac tatggctatg atgatggaac aaaagacggt ggagactggc
    23701 cagtattttt atatgtaaca ccaacaaatc accccgaaag aaaaaccgat aaagagcact
    23761 gtgtctattg ctttaacagg ttaaatagtt cacctgagct ctgggaatct caatttaaag
    23821 atccaagtaa gctaggtata aaactcccta tctatgaaaa gaaagaagga gatgaaagcc
    23881 ttttaagagc taaatctcag aagcccagtg ataacttaac ttcaaaatta gttactgttc
    23941 tttcaaatgg ctatcctaat aagacattag gtaatttaag tgaagatcaa agtcgccgat
    24001 taacacagct agctatttgg cactttactg atggatacgc tacaaatcat ttcaaagatg
    24061 gttatcatct aaacaaagat gaagattcag aattaaaaaa gttaattgaa actgctgaaa
    24121 aaaacttcca aactacagca catacctata gcttaaatct ttatgtaact tcatcatata
    24181 attatagtac aggtaaattt tatcaacatc ttcttggttc cactttaaca ccaaaacttc
    24241 cgaacccaaa tccaggacct aaaccaccag gtgggaacaa tccacatcat ttaccaggtg
    24301 aaaatggtca aactaaatat ccagaaggag aaagcggtga ggcaggagct cctaaaaagc
    24361 ccgagcctaa accagagcct aagccggaac caatgcctaa gccagagcct aagccacaac
    24421 ctgagcctat gccagaacct aagcctaaac cggaacctca gcctaaacca gcgcctcaac
    24481 cagaggttaa gcctcaaaaa ccaaccaagc catcaaacac tactagccag tctagcggca
    24541 agggactacc aagaacaaat gaagcaggca gtctaatgac aggacttgga acaggcttac
    24601 tctctcttct cggattaggc ttcctaacaa gacgcaaaag aaaagactaa gacactaaaa
    24661 gattatctat agtcgtttag ttgatcagta tctagtctaa tacaacacaa aagccttatc
    24721 gcgccataaa tggaacgata aggcttttta agcttggttc aaaaagggta agacaactta
    24781 gtctagcgat gtaaaggctt catcagcacg cttgctagta ccattaaggt catggctgct
    24841 acaaacaagg ccaagaaata aggccaagcc tcacctagat taccgccatt ttggaaagtg
    24901 ctgatgatgg ttaacaccca atgttgtggg agtagctttc caatcgcctg catataaggc
    24961 ggcgtaatac taagcggcca caaacaaccc gccagcatag aggttggcat cacaatcaga
    25021 ttagccaatt gactgctttg ttgcgcattt ttagaaaccg caccaatcat taagccaaag
    25081 cctatagcta acaaactata aagaaagaaa gtcaacaaaa caatggctgt tggaatgtaa
    25141 aagctgacat ttgctaccct gagtaatccc agcataatca ctatttgtat cgcaaaggca
    25201 acaataccaa cacagacata gctcagcatg tattgaaggc ttgatagcct tgataagact
    25261 aagcgattgt agatttgact ggacttatca agcaagatac caccgtacaa gacactggtg
    25321 ctgcctagca ttaggatcaa taaaaagcca gttgttgtcg aggaaacaga cttactttgg
    25381 gaacgatcag ctagggtgat ttctttgacc ttgtaggata gcttcgtgtt atgagctgaa
    25441 atcttcttga aaacctcttg attgcctgct gccgcatcac caatgatatt gtaattctcc
    25501 aagagataat tagcctgcgc cttaaaccat tctgttattt gactatcagc aatcgaacgt
    25561 agagcgatct tttgagtgtc tccttttaga accttctcac caaagcccgg ctcaatggtc
    25621 agcacagcct ccagtgtctt ggcctttagg tattgatcaa tagccttttc ctctagccta
    25681 gtatatatct gatatttttt attgtgcttt aattgcgaca caaactgctt ggaaacctga
    25741 ctcttatcct tatctaagat cccaatctta gcttgacttc cccctgtaaa gctcaaggac
    25801 aaggccagca ttgttgttag cataggcaac aggataaagg tgatatagct tgttttttta
    25861 cgtctaattt tgataaataa ggctttaata aaaggaatca tgctgccacc tgctttctca
    25921 ttctgaccaa agcaaagagg ataaaggctg ttcctatacc aagattaacc attaaggtaa
    25981 ccggtatggg attggactgc ccaccaaaaa taagataaaa caaactatca ttgacccatt
    26041 ttatcgggga aatattagac agctgattaa tcaaggcgct atttaaggtt gacaaaggaa
    26101 tatagcttcc tcccaaaaag gcaaagacag gaatgactgc attagacgct accgtcaaaa
    26161 aggattgatt tctaatacca gtcgcaagcc cgataccgat ggcaacagac aaataaacta
    26221 gcgaggccgt cacaccgata atctgccagt cattagtccc ccaattaaca cgtaacacaa
    26281 atcgggtaaa gacataaaga atggttagct ggactgctgt tgctagcata ccaccaatta
    26341 attttccaag caaaatagca ctatttgaga cccctgtcaa ataaatgcgg ctagccaccc
    26401 cttgctgacg atctgatagc accagattca tcgctgacat aatgctataa aaggtaatca
    26461 tggtaaacat ggaaatagca tagtaatccg ctgagctcat gcctttactg gtttgcacag
    26521 agctagaggc gatatagtct atttttcttt tcttgatgtt gctaatggct tctggataaa
    26581 ggttagcaat cgaatcatag gtcttggcat tatccacata gatattgaca agcatattaa
    26641 tcaaatcagc attctgttgg ttaatgctgt tggtggtcac ctcaatgttt tggtcgctct
    26701 taacctctag agctgccgtc aaggcgccct cgctgacctt ttgcttagcc ttagcgatat
    26761 ccttggtttc tttagcttct aaatgaagct ctttatttaa cagctttaaa aacgtgataa
    26821 agttcttttg atactctgtt tccttgccct caagctgata acgaaccgtc aatttaggaa
    26881 cagtagctgc tgtattaaag ctggacttaa aagcaaagct taaaatcaga atcatcaaga
    26941 taggaaaaac caccatcatc aacaaagcag tccgatccct aaaaatctgt aagctttctt
    27001 ttttgattaa atgaaataag atcataacaa cccctaatct cttagcttct taccagtcaa
    27061 atgcaggaag atttcttcta aattcaaatg cttatgccta atctcactaa aagcaatatg
    27121 agcatctgtc agctgacgaa caaccgagcc aatgtcttca tgttcaatca ggagaactgc
    27181 ttcaagctcg ttatccatca gtctccaatt gggcttatta gagagatcga ttgcttggtc
    27241 agctgcgact gtcaccatga tttgctttgt gaaatcagac tcatagcgtc tttctagctc
    27301 ggcctgactg ccctcttcaa tcacctgacc atgatccata atgtaaatgt aatcacataa
    27361 ggcctcaacc tcttccatgt agtgggtcgt gtaaataaca gtagctcctt gctcatttaa
    27421 caagcgaata gactctaaaa tatgattacg agactgtggg tcaatcccta ccgtcggctc
    27481 atcaaagatg attagcttag gagaatgcac caaagcacag gcaatgttta accgtctttt
    27541 catacctcct gaaaactggc ttggaaactg gcttgcctgt gattttaacc ctacgaactc
    27601 caagcttttt aaaacctgct ccttgagctc acttcccttt aagccataga gagagccgaa
    27661 aagctcaaca ttctcatagg ctgttaaatc aggataaaca gcaatatcct gagggacata
    27721 gccaatcttg gaactaattt ttcgaataga tttataagat tgctgtaaaa cagtcacttc
    27781 gccagcattc aaagggatta accctaaaat agcattgatt aaggttgact taccagcgcc
    27841 attaggccct aaaaggccgt agattctccc ttcctcaatt gtcagtgaga catgatctat
    27901 tgcctttttg ccgcctcgat agaccttgac aacatctttt aactctacaa aactcatata
    27961 ttattccttc tttccaactc taacgctgct ctttaaaact aattaacaga taagttaagg
    28021 tcaataaaag cgaaccaatc aaccaaccat ataataaggc tgctgtcaca caccagacac
    28081 caatcacact aaagaggcat agggctagta gctgctgtag ccagcctgag taacgacagg
    28141 ccttgaccaa ggcatagccc aaaaccacaa gcgtaagacc tgccactgaa tcttttccta
    28201 aaaagagaca tagacctaag taacaaaaag catcaaccag tgtgacaaga cttaacaaaa
    28261 gaaagctagc tgctgcccta tctggtttaa aggctagcca agtcattttt cctaagagca
    28321 ggcgactgtc ctttttcagc ataagatcaa aaagcaagac caaaaccaac agggtcagct
    28381 ctaccaaggc tatgctatac aatagcacat aacaaatgat ttcccagcca aaggatacgc
    28441 gacccaaaaa ggtcagcaaa ccatcaagag ctaaagcatc agaaaataat agacaaacaa
    28501 gcactagacc aagctggatt agaccaagca atagatcaag ccattgctga taggacattg
    28561 ccctgatgtg ccttaaatgc catctgacta agcgccgtct tttatgactt gttagaaaaa
    28621 gggtcactag gattaaaaag gatagcaatg ctagtattat gatcatcgta ccaccttctt
    28681 atgcattgat tgaagatgac tcaagccttc aacccataaa ttgcctccaa catgaacaag
    28741 caacaccagc cataagctct gactaacata ataaatactt ccgtaaataa gaccagtcag
    28801 tattttggcg taaaaaatgg atctgcccat caggaaatgg tttagggcat agcacaggct
    28861 ggtgatcaac aagacaagag caattggcaa tcgccattga agccacaaga tgttaaacca
    28921 aatcaaacga taggtgattt cctcacagca ggccaaaacc aagggatagc ctatctgtgg
    28981 ccatttttgt gtcgttccga caaatgatag gactaaggga agccactctt ttttttgcca
    29041 gcagcggcta agatgtaaaa aagcaacctc aacaaagagc acaacaaagc tcaagataaa
    29101 accaatgatc aaaagacgac catcactatg acctaagggc gctttaatag gaggtgacag
    29161 caggtaaatc cctgttaaga ctagggcata ataaaccagt acagctctta aaaaacctat
    29221 tagattaaag ctatagctat cacgaccctg gccaaaaata gcctgcattg cgatcgaagg
    29281 acaaaaggta gccattaaaa agcataggtt aaggcattgg gtgtacaaag gcatttgtca
    29341 cacctccaaa ctgtctcatg cgtggatgat tagcaaatgg aaaggcagga atgcacatct
    29401 caagaagctc aggagtgagg acacgtgtca cgtaccagcc tttttctgag gcctcaggag
    29461 gagtaatgtc taaaaagaca gcattaggac ttactttttt agtgtaggct agtagtgtct
    29521 ttaaatcctc ttttttatct ttcccagcat ggtttgtcag gtcactaaga cgaacctctc
    29581 ctgaaatcaa gggctcaaag gccttccatt taagctcctg atcctttgga tgagcatagt
    29641 aaaagacgtt actatctagg tctaaaaaca agggagagtc actctcagca ttttgtgttg
    29701 acgttggatt ataaaacaaa ttatagtaat agctatagct aatagctgaa gcttccatga
    29761 ttcctcttaa cagggtatgc ttaggatcca agcccgcctg aaccccaaat aagagataag
    29821 gaccttcatt ggacttgttt ttaaggataa taccaaaggt ataaagcgga ttatcttctc
    29881 caacagtcat gtcaataggg ataatctcat aaagactgtc cttaccaagt ctagcctctt
    29941 ccaaaagagc tagaatttcc ggatcatcaa taatcactct gggacaaggc tttttagtat
    30001 gccagctaag catcatagag tcgatttgaa tatactcaat caagctatta cacatggctg
    30061 cttccagcgt tgtatgagag gctgtccccg ttgaaaagcc tggaatgatg tgcttttcgc
    30121 ctacagcctg attggtctta tagccaacgc aaagcatttg ggcaggcaca tacatctcct
    30181 tatcttcaaa aaacatcgga cacttaaccc agcccaagac atcgtcttgc gtcaccattt
    30241 tatcacacat gatcatgtgc aaatcatggc aacggtcaat ttgttcctgc gtaaaaacct
    30301 gcaaatactc taagggcatg acaggatccg tctggctcaa ttccttataa gaagcataaa
    30361 caatccggtc tgataataat tccccagcaa taacagtggc ataacgctca atgctttcac
    30421 ctaagtattt gatcaaggct tcctcataat gactgccata accaatgata tgatagctca
    30481 cctgactcag ctcaccaata aattgcttgt ggtagtcagg catctgtcct gtcacactct
    30541 ttaagtaaac atcatgagga tggttacaaa taggaacctg agattgattt aagataccag
    30601 ttcggttacc actaaggccc tttagcttat caagaatatg gttgaacgaa gggtaataat
    30661 gtagcatcct tagacctcct tatgactctt cttgaaggag ttttttaaca atctcacgtg
    30721 ttgaaatctg ttgatcctca taccttaatt ttgtcagagc cccttgtgtc tgagaattag
    30781 acattttcaa aatatcctgc acctgaatct caagcgttgg caaatagaca cttaacaaac
    30841 gcccttcaaa ttttgagctt cctgtttgag caataataaa ggcctcactg acaaccagat
    30901 tcattaacac atttaacaaa ggtacataag aggagctaac aggctgtgtt ggcggcaact
    30961 gctgacttgc aaagcgctga taaagcgtgt gatcctgtaa acgtgccagc acccttctct
    31021 ccaagctatc aaaatcagca ctatgaggag gatttaaggt acaagcatgg ataaacggcc
    31081 catcaacaaa gccaagcacc aattgttttt tcaaggccac actgatttca ttaaggtgac
    31141 gcagcatcat aatattcaac cggccttgac aaataacaat actctgatag tctgcgagct
    31201 tctcagataa gcacttcatg ttgcgatggt gctccagagc atctaagcga gaggtaacat
    31261 ctgtttcttg aatgagcatt tttagctcat cgctagccac ctgaaggttt aagttcaggt
    31321 gcttggccag cagctcagca gattcattga catagcttga atcactgata aataagacag
    31381 gtgcagtatc cttagcctgt cctgattcag ctatgaaatg ataattgcct gttaagacct
    31441 tcatgatatt ttcttcaaga gcataagcgt cttcaagcat caataggtcg ttataataca
    31501 aggctgtgat gacctctgac aattttgcaa ataagtcaga ctctagtgtt ttttcgtagg
    31561 tatcagtatc aataactttc ccgttaaacc aatcggagat gatactgtag taggcttctt
    31621 ttaaggcttg tggctcttgt gcaatgtcta aaacagcttc attaaaatcc cataggcctt
    31681 ttctaaagca aaacgtatcg tcaaattgca caatgcgaac attgctattt aattgatatt
    31741 tcattgagac tccttatttc caataatcgt catgtgaatc acatgctggg tcaagccatc
    31801 caagcctagc ttttcttgga ggtattcctt attgtaccct ccaatatcaa cacttccata
    31861 taccaaagct gttgagacca attgaacatt ttgagcaatc tctccagctt caataaaggc
    31921 ataagcagta gcttgatttc catatttacg tgtgtttttg atgtactgat aaacatagat
    31981 aagaatgaca ttgcagtttt cggcagtgat cggtccgtat tcggcaaagg ctctaatatc
    32041 ctcctgatca ctaagatgat gacacctcag cgcgtgctga taaggaaggt attcataaaa
    32101 accgtccttg agtgtttcta cgtttcttgc atagaaaaat aaggtgatgg ggtacagacc
    32161 cccaccagaa gcacaatttc ttaaggctac tgtcttagtc atgccttctt tgatgattgc
    32221 ctgagagctg acaccacaag cataataaag caaatcagcc aaatcctgca aaggcatctc
    32281 ctcatctata aactgcctat gacttctccg gttggtgata caggttgata gggctgctga
    32341 gaccttctta gctttaggaa gtgctatcgt gtttgcccta tcctcaaaat agtcactatt
    32401 tgaaaaggtg gtcactgcag aatccgtaaa aaactcagcc acactggtct taaaccctag
    32461 gtaattgtta ttagccttgt aattcatcaa aaaccgttgg ctaagattgt ctgtttcatc
    32521 aggcatcaaa tgctgtgcca caagctgttt tgatgttttt aataccgttt gatgatgata
    32581 ggttgataac gataagtgat tggtattaaa ttcaaataac tgtcgtgctt cttctcttgt
    32641 taggtcactt tggttatccg aacgttgttt ttccttagaa aaaaatggca taactgtctt
    32701 cctgtaatat attaataaat aatagtaatt agcaggtacc gactagtacc tgctaattac
    32761 tacaagacgt tgacatcaag ctgattgtct tcgtctcttg tcatgtaaca cccctatcca
    32821 acaccagcta acaccatcaa ttacaaactg taaccttagt cgctagcaaa ctaatgattg
    32881 tgacctagct attaactatt aaatagaagt attaaagttt acgcttttgg ctcagctgca
    32941 ccataattgt tgtttatggt agtattgccc catgaagctg agacgcagca acaacaagaa
    33001 cagcaacagc agcaaccacc aggagcaact tgagttgttt ctgctacact agtagctaaa
    33061 atatttgaag caaattgtaa cataatgctt acctccttat atcgcctgat cggtaaaaca
    33121 aaacactgat aagagttaaa tgagaatacc tctcaactga tagcaaaagc aatcatgagc
    33181 aggtatccag caacacaagg ctagctattt tgtatcgccc ttgttaaagt gaccattcaa
    33241 ttcttaccaa ctatattata ttaaaattca agacatatgt aaatactttc tttaatattt
    33301 tcttacaaaa atgtcattat ttttccagaa aggttagctt attgagcttg acaaagtctt
    33361 aagcctatct ctttaatggc atttataaac tatcagtctt tttaatgaaa cgcattaaaa
    33421 taggtagaga tattattatc tctacctaaa ctgtattgat gagacagatg gctagtacct
    33481 cacaattaac catttctaaa aataatgact cttttgtcga aagacctaat gattaaagct
    33541 atttgtcttt gtttatcttt ttctcattag taacattaaa tcatggcaaa atatttatat
    33601 tcatttaata atcaagattc cggatcatca agtgaccgtc catgcagacc tttttcgcgc
    33661 tgcacctgtc ttaatttctc aggagtaaca tcgtttccgt cttcatcaac aatcttaatg
    33721 ccttcaatgt gatggcgcac tgagcggcga tagccctcaa tgtattcctc acgcagcttg
    33781 gcctgctcta ccttttcagg accagtcaag ccaactgttt ttttcttttt tgcaagctcg
    33841 ttaatacgag cgattttttt aggatccata aatcacatat aagggctgca ccaaaagcag
    33901 tgagcagctg atgaggcttg atgatgggct agacagcctc tttaggaccg ttactaggac
    33961 ctttcaagtc ctttttcacc agctgtgcca gcaagggctg cctgcaaatg gggctgcctc
    34021 taatcctttc tctttcgttt gtgacataga gtactgcact ctttttgtct atatctaagg
    34081 ctgtgccagc agctgcttag ccttatgctt ctgccaagaa ggctgtagca agcttcttgt
    34141 gaaaagctaa aatccatgct cactttacta acagtgttcc tgatgctttt attgaccact
    34201 gaccagcaca gctattgcta gcaaagctag cccaagacga tatctcgtag taagcaagag
    34261 gactgatttg actaagtatc aattgcttga taagtcttga gtgcttaggg aaggacttat
    34321 cccaaggcag gtaatcagtc acctatatca tctagggaat acgaacagct aacacagggc
    34381 gatgtgctta atcttacaca gcgaattatt tagtatttaa tcggtcaaag gccgcaatgg
    34441 tctctacctt tttaaccagc tctgctaaca gcgctaaacg gttacgtcta atagcttcgt
    34501 cctctgtcat gaccatcgta tggtcaaaaa agtcatcaat aactggacta agggcaaaga
    34561 cctgagctag ctgttctttg gctgatccag atagcactag tgaatcaaca gcctgtgcca
    34621 aagccctttc gtagtcattt tcaaagaggc tagcatcaat cagcacagcg tcaactgcct
    34681 ttttcgctag attaaagacg cgagacagcg actcgacagc aggcttgtag gtgtctagct
    34741 ggcttgccgc agccagagcc tccgctcttg ctaacagttc tggtacaaca aagcttgagc
    34801 tagccagaac tgcttcacgt atatcctttg gaatggctga gcccatcatt ttatccacac
    34861 gtgcacaaat aaagtccagc acctcagcct tatgctgata ggtcaagcta tcaaatgaca
    34921 gctcatatag gctatcaatc agcttatcca taggaatgct ccagccgaaa tgctcaagaa
    34981 ttcggacgat cccctgagtt gcacgacgta gggcataagg gtcatttgag cctgacggta
    35041 tcaaaccaac agagaaaaag gacagcaggg tgtctagctt atcagcaaga gcaaggacag
    35101 caccaacctt tgtttcaggc agctctcctt ctgccgaatt tggcaaataa tgctcacgaa
    35161 ttgctgttgc gacagcagca gcttcgccag ttaaaagggc gtatttctcc cccataatgc
    35221 cctgcaactc atcaaattcc ccaaccatac cagttagaag gtcaaattta taaatctggg
    35281 cagcacgagc gacagcactt ttttctgctt ctgagagccc agcctggtca gcaagaaagg
    35341 ctgcaataac cttggtccgc tccatatgct cagccacaga gcctatcttt tcatggaagg
    35401 tcacatgagc tagcttagca accaaatctt caatagataa cttttgatcc tcacgccaga
    35461 aaaattctcc atcttcaaga cgagcaacaa gcaccttttc attgccctta atcacatttt
    35521 gaagatgctt agcattaccg ttacgaacag aaataaaatt cggcattagc ttgccagcct
    35581 gatcacgcac gacaaaataa cgctgatggt tcttcattga ggttactaga acctcttctg
    35641 ggatttccag gtacttggga tcaaaacttc ccatgaaggc agttgggtat tctactaggt
    35701 tgagcacctc atttaagagg tcctcatcaa tatccacctg aaccttttgc tctgcttcga
    35761 tggctctgat ttgtgctatg atcatctctt gacgctcctt agcagaggca atgacaaatt
    35821 ggctgcgcag gtcagcctca taggaatcag cacttgtaat gctagtctct tctccaagga
    35881 agcgatgtcc gcgactgata cgtcccgaat gaatgtctaa aaagtcaagc tccaaaggct
    35941 catcatctaa cagtacaatc aagctatgca ccggacgaat atagtcaaag ctattgttag
    36001 cccagtgcat gctgactggg aaggtcaagg aagcaagaac ctctggcacc gctgctaaga
    36061 cgtccttagc ctgcttgccc gcttcatgct tggtgacata aacgtattcc tcacctttga
    36121 cctctcggaa ttcgatgtca tcaacagtca agccctttcc acgaacaaag ccctgagcgg
    36181 cttttgaaaa ttgaccatct gcgtcaagag caattttttt agagggtccc ttaaaatcct
    36241 ctgtcagatc agtctgctga tcagctaagc ccagcacacg cactgctaaa cgacggggcg
    36301 ttgaaaagcc ttcgattgcg tcatagctaa gccgattggc cttaagaaaa tcagccatac
    36361 gttcaacaag ctgcttttca ctaggtgtga caacgtaggc aggaagctct tcaagaccaa
    36421 gttctacaag taaatctttt gtcatcatta aaatcctatg ggcatcaaat ctaaaagaga
    36481 agaccaaacc gatcctagca tgccttgggc aagcttggac gatcctttgt ctacaagatt
    36541 tgtcccatct ttctttcctt tcttcaagtt atggggtagg tttaggagac caaatcacta
    36601 gctcctaatc ctgcaagcct gctaataagc tgcctgttag acaagatcac ttagcagaaa
    36661 gactgagctt aacaggacta gtcatcaggc ctttaagtct catcgctttt aaaaagcacc
    36721 taccagatag gtaagctgct agcagcaact agagcttaca agatcataca agctgcattg
    36781 actacaagga actagtttag atccagctgc ttagtcctct gccagcaagg ctactcggct
    36841 agcatcatcc aacaatggga agccaagctt tttacgctct gcaacaaagg ttttagcaac
    36901 gctacgagct aaatgacgaa tccgagcaat atagccagca cgctctgtca cagagactgc
    36961 accacgagcg tcaagcaggt taaaggtatg agagcatttc aagacatagt cataggctgg
    37021 gtggacaagc ccttgtgcta aagcacgctc tgcttctttt tcaaatatct caaagttttc
    37081 aagcagcatg tcctgattgg atacctcaaa ggaatacttg gaatgctcat attctggctg
    37141 aagaaaaatc tcgccgtact taacaccagg tgcccattcg atatcataga ccgaatccac
    37201 ctcttgaatg tatgaggcca agcgctctaa gccataggtg acctctgctg tcactggtga
    37261 tgttgctagg cctcccacct gctggaagta ggtaaattgt gtaatctcca taccatcaag
    37321 ccagacctcc cagccaagtc cagctgagcc ggttgaagga ttttcccagt tgtcctcaac
    37381 aaatcgaata tcatgctcca atggatcaat gccaagtctt tcaagagatt gcaggtaaag
    37441 ctcctgaata ttacttggag aaggcttcat caccacttga aattgatggt gctgatacag
    37501 acgattggga ttttcgccgt atcggccgtc agcaggacga cgagatggct ccacataggc
    37561 agcattccaa ggctctggac caatagcgcg aaggaaggta taaggactca tggttcccgc
    37621 tcctttttca ttgtcatagg cttgcattag catacaacct tgatcattcc aatattgctg
    37681 tagcgtcaaa ataatctctt gaaaggtaag tttgttactc atgatttcct ctttctattt
    37741 tttatgtctt gtcgcaggcg ctaaccaaga gctggctatg gcttgactgc tggttggctc
    37801 ttaaacagct tttcaaagag aaaaaccgcg cctatagcca cctacaccta aaggcatagg
    37861 ggcgtcaaaa cgcggttcca ccctaattta ttacttcatt tgatcttgtt gataaacaga
    37921 tgtcaagcaa gctacaaaca cctgagccta ctctttagag aaagcgccaa ccagcagtac
    37981 catcactcgg ctctcaccag ccccgagctc gctttagatc agaaacctgc tattttcttt
    38041 cctattggtt agtttatcac aaaatcctat gattgtctaa tcaactatta tgattttgga
    38101 cgagttccgt ttggaataat aacctcagac aagagcctat tttcttcacg aatgcgcaga
    38161 taaatcacaa taatatagca agggaaaagc agcattgccg taatctgagc atggcaaagc
    38221 aaagcaatac caaccagctc tggagcaatg tttaaaaagt aattggggtg cttaacagtc
    38281 ttaaagagcc aatgatcgac atatttatgg tcctttgcca gcatcagctt cactgtccaa
    38341 atatctccca agatccgagt tacctcatat agcacagcta tcgaaaaaat catcagcagc
    38401 aagccaagaa agctaatgcc atcaaactta atctgcttga gcaatgcctc tgtcacagca
    38461 aagacataaa tcatgatatg cagcagggtc aaaaacttag tgttttgcgc accaaattcc
    38521 ttgcccccat tagccaggat agccttctcg tttttgatcg atttttttaa gaatactaaa
    38581 cgaatagcaa acatcaagag catcaataac aggataatca aagtaagact cctttattct
    38641 agtttaatct gtttctttca cgaaacacta attaagatta tagctaagtt acacagcctt
    38701 gtcaaaccgt tttcaaaaaa aagatgtctt tctttgatct ctaaaaacaa gaggtcgtca
    38761 cacagcacca tcaagagacc tcatcaaagc tttaaggtcg taccaaatca ccatcaaaag
    38821 acagctccta gactcagtca attcacgagc agcaagcagc acccaagagg cattttgcag
    38881 gcctgaccta cttcgcctgt cgtaaacaca aatcctcaat atggtaaata gcgtcacatt
    38941 gcgctgcaac ctcatcgctg tgtgttgcca ttaagacaat catatcctca gtctgacaag
    39001 ctctgatggc ttgtaagacc tcctgctcag cctcaatatc cagggcgcct gttggctcat
    39061 ctgccaataa cagctgcggt gttttgacca aagcacgagc aaggaccact aatgtagctc
    39121 acttaatccc tgcagctctt gctaaaagtc cttggtatca ggatctggga tagctgacat
    39181 acccggcagg caacgaatgc gctctgaatc ctctggacta atctcacaat caaaaatagc
    39241 catattttct actatgcgtt ccttgtgcac cgacttaggt agaggaataa agccctcagc
    39301 aatagaccaa gcaagggcta gctgagccac tgtcttgttg tactttttag ccaatgcctg
    39361 catggtatca tcggcaaata tctctccttg tcctaatgga ccccaggcct ctagcaaaat
    39421 gtgatgcctg cggcaataat caaccgtctc tttttgatag cagccaggcg ccaagcgaat
    39481 ctgattgact gctggtgtaa tggttgctgt ctgtttaaga gcctccagat ggtgaaccat
    39541 aaagttgctg acaccaatcg agcgaaccaa gcctgcttca acagcctcct ccatataaga
    39601 ccaagctgct gcattggctg cttgccagca atccctaaga gccttaggat ttggccaatg
    39661 aatcagataa aggtctacat actctagtcc aaggcgctca agagaggctg ctaaggctgc
    39721 cttagcgcca tcatagctat gagcatcatt ccagagctta gtggtaataa agagttcttc
    39781 acgaggaacg cccgaatccc gaatggcctg tccaacactt ttttcattgt gataaatggc
    39841 agctgtgtca atatgacgat agcctgcctt aatcgctgct agggtggatt ggtaggcctc
    39901 ctcaccatca gcagccttaa aggtcccaaa gccaagcact ggaatagcaa gaccattagc
    39961 cattgttact gttttaatca tatctaaaac ctcctttttc attgtagcac aatgataagc
    40021 aaagcaaaaa gaattgagct gatcaccagc ccaattcctt tgctgtatta agcctcaaag
    40081 gccttttgac catttaggta ggttgctact aattctaagt ccttatcaag aacaataaag
    40141 tcagcagcat gacctgcctt gatttggcca cagacatctt caataccaac cgaagcagct
    40201 gggacgtaag aggacatgtg aattgcttct gctggacttg caattcccca ggcaacaaca
    40261 tttttaatgc cgtcctttaa ttttaagata gagcctgcta gattaccact atccttcaag
    40321 cgagctgtgc cattttccac aataaccgga aactctccaa gcatgtaatc accatctggt
    40381 gaaccgcctg cacgcataca gtccgtaatc aaagccacat gctcatgacc cttttgctgc
    40441 atcaaaatat cgcaagcaac aggtgagaca tgatgaccat cgcagatcag ctctgcaacc
    40501 gttccaggaa tattataaac agccccaacc ataccaggct cacgatgagt caagccacgc
    40561 atcccattgt aggcatgaac ccaaacacta gctcctgctg ctactgcctt tttagcctca
    40621 gtataggtac catttgagtg acctaaagct actgtgacac cctgcttggt cacctcagag
    40681 acaaatgctt ctacgccatc acgctcagga gccaaagcta tttttttgat caagccctta
    40741 gctgcttttt gccaagctgc aaattcgtct aagcgaggat ttttcatata tatcgggttt
    40801 tgggctccct tgtattcctc agtgaagtaa ggcccttcaa aataaatccc ctgaatcttt
    40861 gctcctttga cctgatcggc aacagaagca acggttgcag acacctgctc tagatgctca
    40921 aaggttgacg ttagggtagt cggtaagaag gaggtcactc ctgttgataa gagaccctca
    40981 ctgatggcat ggagaccttc tgctgaatta tccatcacat cagcaccagc atagccatga
    41041 atatgagtat ctacaagtcc tggtgctatt tgatagcctg tataatcaat aacctctgcc
    41101 tgatcatcaa cagtagccgt ccaataacca aatgtgccat tatttagctc caaatagcct
    41161 gctggcttta cctcgttggg gtaataaaag caatctgctt taatatagct tgtcatcttt
    41221 tttcctccct ttttcgttta ttatacgcct taattcttat tttgtaaatg gtatatacca
    41281 gtccttctgt taaaaagaaa aacctgaata ctatttcaag ttttcccttt tattagagct
    41341 gtcctgaaag tactttctca gctagattta gggcgtggtc agtgatacgt gtgtaatgag
    41401 atataatgtc aataaaatta atccctgcct gtgctgtgca ttcgccacga ttgaggcgtt
    41461 cgatgtgtgt tttacgcaat tgacgctctt tttgctcaat cgtcctatga cgctcaacaa
    41521 tagactgggc tagagccttg tcactatcca caatcgccct aatcgcatct aaagttaaac
    41581 agtgggtcag gtgatacatt tctgttaatt caccacgtgc agctgctgaa aagccaatct
    41641 gctttgctgt aatcccctca atgagagtcg ctaacgactc agagtggtca ccaattcgct
    41701 ccaaatcacg agacgaatcc aacagacctg ctaaaacctc attttcacta ggactaaggg
    41761 cttcattgga aatatcaacg aggtaagtgg tgagctcctc atcaatcgta ttgaccgcct
    41821 tctcatatcg cctcaccttt tcgccaaact tgtcttctgc tgtcataatg tagctataag
    41881 acgcctcaaa agcctgaata gcataggaag ccagatgtac caattccttg tgggcatttc
    41941 ccaaggcaat agaaggagcc tgagtgatta gtaaacggtc caaatacaag gcttcatatt
    42001 tgacgatttc gtcttcacct ggaattaagg tggtcacaag ctttgccaga gtgttgataa
    42061 aaggaagcag caacagggta tttgtgatgt taaaggtccc atgtgaaaag gcaatggtca
    42121 tctcaggtga cagggccaaa acagactgaa gccatagcat aaaggaggta aatggcatca
    42181 gtaaaatcat aaagatgacc gtcccaataa cattaaaaag aatatgagca gcagcaacac
    42241 gcttagctgc aatattagag ccaatagctg ccaaaaccgc tgtgatacag gtaccaatgt
    42301 tagagccaag caaaatagga atcgcaccct gcagggtcaa taggccaccc gaaaaaagcc
    42361 cctgtaaaat accaataatg gccgccgagg attgaatcag catggtcaat gctgtcccga
    42421 taaaaacacc ctgaaagggc ttgtctccaa gcgtcgctag gtaatgctga aaggctgaga
    42481 ctgattttaa aggatccatc gcatcaccca tgaggttgag agaaaagaaa attcctccta
    42541 caccaaaaat gatacgacct aggttattga gttttttatt tgacgtgaaa aagagacagg
    42601 ctgctccaat aaaaatcatg ggcagggcgt aatctcccag cttaaaacca atcaaaaagg
    42661 aggtcactgt tgttccaatg ttggccccca tgacaatacc aatcgcctgc tgtagggtta
    42721 aaaggcctgc agatactagg ccaactgtaa tcaccgtcac acccgagcta gactgaatca
    42781 aagcagacat agctattcca accaagatac caaagaaggg gttgcttgtg tacttgtcaa
    42841 tgtaatacct aagcttatca cctgcggcct gctgcaagtc gtctcccatg tatttgatac
    42901 tgaaaagaaa aagacctaag ccctgtactg ccccccaaaa aatgaaacgc aatgtcttgc
    42961 caatttaccg acacaatatt gtcctcactc gcttatttat tctcttctat tttaatgtat
    43021 ttattcagtt atcacaaggg ttttttaatc cttttaaata gtgctcattt agaacctatt
    43081 ttagagccct agtcctcttt tcattttcct atattcaggg tataatagtg ctactcaagc
    43141 gacaatgatt tcaaaggaga taccatgaga aaaccgacaa aagagaccca ctacctcatc
    43201 attagcttgc ttactattgc cattgcagga ggggcctacc ttatttttag tagcctctct
    43261 ccaaagccag ctaccattac cacccaatct aagggctatg agctgttaac taaggctcaa
    43321 gcattagtca aggaggccga agacaaccca actaaagaag ctatcgcaaa ggctcaaaaa
    43381 gcaattaatc agctaaaaaa gacccagtct aaggaggaat tacaggctcg actaacagct
    43441 atcagcttaa agcacaatca agaagacgtt gctatcaagg tcctaaaggc agccgaggac
    43501 aatccaagcc ctgaacttaa ggaggctgca caaaaagcca ttagtaagct ctctgatgag
    43561 gctaaaaaag ctgccttaca ggctagactt gacgctattg gactttcaaa gcctagcact
    43621 gcacagcctg agactgcaac accagcagca gaaaaaaata tagcaccagc tcctgcggct
    43681 ccacaaataa agcataccac accgtcttct gggggaacga cgccagcacc gaaccctaaa
    43741 cctagtccta agccgaatcc tcagcctagt cctagtccag ctccagagaa cccagagcca
    43801 acgcctagtc ctaaccctca gccaaatcct caaccagaaa ccaacacacc tagccctcag
    43861 ccacctgcaa cagagcaaag tgaaaacact gctccagcag gacaaaacta agaaagggca
    43921 gccagagctg ctgtagctta gttacacttc ttagtacagg caataagggc ttagctactg
    43981 aaataatgct aaacttacga ctaataagct ctctgataaa aagaggcttt aggtgattaa
    44041 aaacagctgg ttctaaaagg attccagctg tttttgtgct tcttaattga ttttgaggta
    44101 ggaagagaag ggaggcttaa tcaagtcgat aagtaatccc atatcctctc ctaactctct
    44161 atcagcttgg ctatgattat agagcggctc acccttacgc gctttggtga ttcgtcatgg
    44221 atattctgac tggcttgacc atttgagttt tttcctcagt gtcactccct aagactttta
    44281 agggactgac gaggtgatta gcatgcacaa caaaaagccc ttaaacacac ctttaaggac
    44341 cttgtattca gcttaatgcc tctatagtat cagggatatt tgttaaggca gctctcagct
    44401 aaagacttgt gataaagacc tatgcctatc cgaccactag ctagagtcaa gctgtgcata
    44461 gctcagcctc tatgactaac agaaaccaga ggcagcgtta gatcactttg cttagcttaa
    44521 acctcatagc ccatgagaag cccttcagct tctgcataga agctgcatag gcctgaggct
    44581 gggctggttt gaatctctgc ttctgggtaa atcgctctaa ttttttccgc aatttgctca
    44641 cagatcttag ggtttttggc gtgggagata aagactcggc ctcctttata gcctgccttt
    44701 tgaatctctt ctaaaacagc tgacactgcc tttttttgac ctctggcctt ttgaagcagc
    44761 tcaagcgtgc cttccttact tgcctgtcct accattctga tgtttaataa gccaatcacc
    44821 ttaccaatga gcttattcag acggccattt ttaaccagat tatcaacctt ggccaacaca
    44881 aaaacaagcc tggttttttc ctgataagct gtaattttct caacaacctc atcaaaagaa
    44941 agcccctgat tgatcaaccg ctctagctct aacacaatca aatccatctc accacctgct
    45001 gacaaagagt caatcacatg gatattggca ttcggatttt cctcaagcaa gtcattttga
    45061 gccaatctag cactattgtg actgcctgag agcgtaccgg taatggtaat ggcaatgacg
    45121 ttatctgctc ccctgtaggc ttgtaaaaaa gcatcaggac ttgggcagct tgaggttgct
    45181 ggcttagagg actgatacat agtctccatc atttgatcaa tatctagacc atcatcatct
    45241 ctaaaaatat ctgaaccaat ctgtagggtt agcggcacac gctcaaagcg caggtgattg
    45301 gattggcttt ttagggctct aatatcgcag cctgaatccg atacaatttt ccaggtcatt
    45361 cgttttcctc ttttccttca tagtctgttt tggttgacaa agtaagcatt ttcccataaa
    45421 attatatcat cactagctag acttttgcta gctaaacgac atcagatgta acacttgaaa
    45481 ggtatttgta atggctggta aaccaatttc taaacagtcc cttcaaaatt tagcccactg
    45541 caatcaggaa tccagacggt taacacgaga agctattgaa attgctctgc ttagcttact
    45601 agaaaagaag cccttaggac acattaccat ttcagaattg gtagctagag ctggggtttc
    45661 aagaaatgct ttttaccgca attacagctc aaaggaggat attcttgagt gtctgttgac
    45721 ttctgttatc agacgtatct ttcgtggact gaaggccttt gatctaaaga cacaggccta
    45781 tcaggcatgg ctttatctgt ttacagaggc caaaaaagaa gcgacgctac ttagtattat
    45841 ctttaaccat cacctgcagc agctcttgac gcagatggtt accaagcgtt tgagagccta
    45901 ccaaaagtgg caggaaaaaa agctgtctca ctacgcactg ctcttttgga gcaacgctat
    45961 tgtctcagtc ctttccaatt ggatttctga tgatatggtt gttcctgctg aggagatggc
    46021 tgctatgggg ctgcccttat tagcctagtt gtctctagat cacctatagc tcctagacaa
    46081 cttcccaaga aaccaagctt gcagcatcag acaggacgct tggctggctt gacttaagca
    46141 ctggcactgc ctaccaagat atgtactagc cctactacag gcaaggtgtg acttgtcgct
    46201 cgctgttgtg cagaggctta aaggctctta catttagctg gacaataaaa aaagactgaa
    46261 gaggctggct ggattagcct gctcttcaat ccagaacctc ctttgttgga ggttttttcg
    46321 tgttttattt ttcagtcgat ctcacacacc taggcttgtg gtgttccaag acagctcagc
    46381 tctagtcaac acctctaaaa ctgagcttat catctctagc ttttggaggc cttttctgac
    46441 gggctggttt gactgtgctt aagagccctt tgtcaatgca aattgattaa tggcatgggc
    46501 cacgcctgct tgatcattgg agaggcttac cttgtcagcg acctttttaa ttgcctcatc
    46561 agcgtttccc atagcgacac ctaagccagc ataggctaac atttcaagat catttgctgc
    46621 atctccaatt gccatcactt ggtctgggcg cagcttcaga tcagcggtta attccttcag
    46681 ggcagaggcc ttggtcacac actccggcat tacctctagg attgtttctt gactgcgaac
    46741 cacactaaag cttgcgctga gtttttctct aacaagagcc tcaaaagtat ctagggcagc
    46801 cttttctccc atgtacatgg cctgaaatat gatttgactg ctgttggata actgagatag
    46861 gttagtagcc tttacctttg taaaaaccaa atcaccatca gcctgaacca tatctggaac
    46921 cttgctatct atcacaagat aatcacgctc tccagtcagg gtgaggtaaa tatctgaaaa
    46981 gggctgagac agctgataaa ggtgctcaat agctgaaaag gtcaggcttt gataatgtag
    47041 cagctcccag cttgggctcc tataggtgct acagccattg tttaaaataa ggtactcctc
    47101 cttatcactc aagcctaatt gctcaaaata cggccttgtc ccagactggg ggcggcctgt
    47161 gcagagaaca acttttatcc cctcttgtgc agctgcttgg atagccttaa tattctcttt
    47221 tggaatgtgc tttttgctat caagcagagt accgtctaaa tcaattgcta taagctgaat
    47281 catcgtctca gtcctctttc cattttatct taggtaggtg ccattgtctt ttgttgccaa
    47341 tcatacgcat gactgtcaat aaaacaacca gcaagtagca ttcaacattt gaagtggcca
    47401 gcttaaaata aagcacaagt gctgctataa tagaccagcc agcataaatc tcacttctaa
    47461 gaacagttgg cttacggcct gccaggacat ctctgaccac acctccgcct gcccctgtaa
    47521 gaaccgctgc tacaataaca gcgcttaagg gctgggctag tcgaacagca tgtagagccc
    47581 cctgaacact aaaggctgca agtccgatag catcagtcag caccgctgct ctcacccagc
    47641 ccttagccac aagcttagga aatagcatga tcagaataat agctataaaa gcgcaggcaa
    47701 attctggtct ttgtccccac aaggcttcaa taggcagccc gatcagggta tttctaatag
    47761 ccccaccacc aaaggctgtg acaaagccta gaataaaaat ccccagaaca tcaaactcct
    47821 cctccatagc gacaatagcg ccggacaagg caaaggctat cgttccaata atgcttaaaa
    47881 gctcccacat atcaattgtc ataactcacc taatgcttcc taatccccta ttagtctacc
    47941 atctttttaa tcaaaatata agtcaaaata agagcaaggt cctcaaaaat cctactgatg
    48001 acctgttttt gtttgcacca aagatttagc ccctatatag gctaggctcc tagtagcagg
    48061 agttaggagc gatagcttgc caaattcaca gccttgttat tttccatgag aaagggctct
    48121 gctgatgtct tggtttgata ggtcttgtat ttatggtaga ggtattggta gcaatcctgt
    48181 ttttgatcaa agaggatggc ttggtagggc tcttggaagg acaatttctc aacaaacaga
    48241 tacttgctct tatactccac tagcactccc acatgaccaa taaaaaggta atcaccatct
    48301 agctgatcgt gaatcacaac agcaagcatt ttggctgggc cattaaagct aacagctgag
    48361 aaatgctctt gcatatgctt ggcatgcacc tgaatatcct tggtggcttc cgttttcact
    48421 cttgaaaaca gctgcttaaa gcgctctgtc tctgcctgtg taaagagctg gcttgtggta
    48481 atggcgtcct cgtccataaa taaaagcgta tcatcactgc tggtaggcgc aatcgtcatg
    48541 ctatccttta gaagcataaa ggtgttgatc cggcaattag ttccaatgaa attgccttgc
    48601 ttttgcgacc acaactcatc gattgctacc acatcatagt caggctgctt ctgataggta
    48661 aaggcccctg tcaagcctgt tttgccaact aggctattat attcttgtac accagccata
    48721 aaggcattga cattagcttc cttcagctga tgtgataggg cagccctgac ctcctgctgg
    48781 ctctttgcac tgttcatgtt ggataggaaa agacgtccct tcttagcctg tggctctttt
    48841 tgctcctgct tgggctgatc agactggtga gaagcctggc aagccccaag agttgccgta
    48901 gcaaggatta gcaaagacat cattactttt ttcatcataa cctccttttt aatgagtcat
    48961 tcaagctggt actctccatc atcaccaaat gagattatca gcagctggca gctaatacga
    49021 ggttgctaca acccacttgt tatctcttta tgtcatgacc tcatcgttac cagtatagca
    49081 taaaaaagaa aagcaccagc tcttgaagcc ttgcagccct tgtgccggtg cttttcgtta
    49141 ggagattaca ctgaaatagt ttttgtggta gctagctgct gataccaata agcgcttttt
    49201 ttagggtaac gcttttgggt ttcaaaatca acatagaaga ggccataacg cttatcatag
    49261 ccatttgacc aagaaaagac gtccatcaag gaccagataa aatagccctt aacattagcc
    49321 ccagcaccga tagcgtctgc aatcacagcc aaatgctgct tgatgtaatc aattctagcg
    49381 tcatcatcaa tcctgccatc aatacaggta tccttgtagc caaggtcatt ttcagtgata
    49441 taaatctttt tatagcctgg atagtctgcc ttgatccgca tgatttgatc gtaaagcccc
    49501 tgtggataga tcatccaatc ccagtctgta cgcggcacat caacatcaaa cacgcgttga
    49561 ccaaccccct ttatctgata tttggagccg cctttttctc ccttgccatt atgaatgatt
    49621 tcggtctcac catggctaat aataagccag acttctcatc acgtacctta gtggctggca
    49681 ggccatattc agggtctagc aggatagagg aggcataggg ggttagctcc tctgatacca
    49741 gagcctttag ggcttcgatt tgccaaggag ctggctctgt gtcttggtgg gctgccatca
    49801 tgcgctttaa agccccgcgt tgatcaaagg ccaaggccga aatgattccc ttacgactga
    49861 ccttttctaa ataagctttt ttgtttcttg ttaatgtcat cttatacctc ctctacttga
    49921 atacggtcaa atagctcatc aaaatgtgcc atgttaacat gacctgttct tgtttcttgc
    49981 gcatttaaca tgcctaaaac attggctttt ttcagaagcg tctcatcgtc atctccttct
    50041 gccaaagccc aagcaatccc tgccacagta gcgtcaccag atccaacagg attgactacc
    50101 tcaattttag gaatggtaac acggtaaaac ctgttatgat gtttggcaaa ggccccttgg
    50161 gcaccaagag aaacaataat ccattctatc ccttcaaata aaggttgact caacagagag
    50221 attaaacgtt cctcatctaa tgtgacaggt tggcctatca aatcctccaa ttcttccaaa
    50281 ttgggtttga taacagttgg tttatctttg ccagccagta ccgcttttaa aggagcacca
    50341 gagcaatcta aaaccacttt gctgccatag actctcgcca tagtaatcaa gtcttgataa
    50401 tagtgagcgg ccagaccctt aggcagactg cctgaaaagg ttaagacatc aaactgctta
    50461 gcaataatac tcatgtggtt caaaaagcct tcggcctcgt ccatatcaat gtagggacca
    50521 gcttccagaa tttccgtctg catgccttca tgtaaaacag caatacaatt tctcgtttcc
    50581 cctttgattt tgaagaattg gttagaaatg ccctgttctt gtaactgatg aatgacaaag
    50641 tcacccagtt tcccaccaat aaatcctgtt gccacaactg actgaccagc ttctgctaac
    50701 actctggtca cattcagccc cttaccaccg gctgtttttg tcgttctgtc aacacgatta
    50761 accgtgtcca aagtcagacg atttagagga taggaaatat caatggatgg gtttaaggtt
    50821 accgttaaaa tcatcgcttc tccctaatcg tggtagtcac cgcgatccca tttgtccaaa
    50881 aactctgtaa agaagtcagg atcttcttgg ttagcattat gactttccaa atgggctatc
    50941 ttagcaatta acttcttatt ctcttcggtt tccttatagt ctgcctttat aaaggcctca
    51001 ataatatcac acatcaaaag ctcacctgtg attttaccac caaagccaat cacattggca
    51061 ttcaattctt ctttggcata aagcgctgtt gtcatatccc taacaagcgc tgagcgaatg
    51121 ccaggaacct tgttgacagc attagtgatc ccaacaccag tgccacagat acagacacca
    51181 agatcagcta ggccattggc gacagcctca ccaacccttt tcccaaaaat cgggtaatgg
    51241 gtgcgggtat ggtcataggt cccacagtca atcacttcat agccctttga tttcaaaaaa
    51301 tctgaaacag ccattttttc atcagtcaca atatgatcac agccaatagc aattttcatg
    51361 atatcctccc ttcgttaagc cattttattg agcatgtcaa cacgaatttg atgacggcca
    51421 ccatcatagt gaccagtcac aaaaccttta gcaatattct tagccaattc ttgacccaca
    51481 atttctgctc ccatggtaat catgcgggca ttgttatgac cgcgagtcat gtaggcagag
    51541 cgttcatctg acacttccgc agcgaccata cctttgattt tggtagcgac cataaatggc
    51601 cctgctccat aagcatcaat cataatgcct agactttcct catcagcctt gagcgcccta
    51661 gcaactgcta gagtattgtc aacaaagtca tcagcaatcg ccgtcacatc tgtcacatca
    51721 aagccttcct gctgcaaaaa gcctttaata gcctctttta gatcatttcc atgtgcatct
    51781 gcacctaaga taatagtcat aggatctcct tttattgtca ttaccgttca aaattgttta
    51841 tttttgtttt gttttttatt attttgttgt ttattgaaaa aagagactgt ttatgctatt
    51901 atgagttaac aatacaccag agaaagtagc ggcctatgct taagcgtgaa agattgttaa
    51961 caattatgga aaaggtaaac gccaacggct ttatcactgt cactgatatt atggaaagcc
    52021 taagggtttc agatatgaca gccaggcgaa atttagatga gctagcaagg gctggaaaat
    52081 tagtacgtat tcgtggcggt gcccagagca tttctatgcc tcaaaagctg gagcgttcaa
    52141 acactgaaaa gctaaccgta caaattgaag ctaaaaaaga gattgccaga tacgctagtc
    52201 agctcattaa tgatggtgag accattttta taggccctgg gacaacacta gaatgcttgg
    52261 ctgaggctct aatcaaccgt cacatccgta ttattaccaa cagtctgcct gtttttacga
    52321 ttcttaataa aagtaaaact gttgatctca ttcttatcgg tggtgagtac cgagccatca
    52381 caggagcctt tgttggcagc cttgcaagcc agaccatctt atccttgaag tttgccaagg
    52441 ccttcatcag ctgcaacggt atttataaaa atgacattgc cacctacagt gaaaacgaag
    52501 gggttattca gcgcctagcc tgtgacaatg ccatcgaaaa atacctgctc gctgacaacc
    52561 aaaagtttaa cgcctatgac ttttacagct tttatcacct tgacaatatc gacgccatta
    52621 tcactgactc caagattagt gacagcgtta aggagcgtta ccgccaattt gccaagctct
    52681 taatcgcaag gccagctgac aatcaggtca gcagctagac agcctgcctc tctatctgtt
    52741 tccaccctga gtccagcagg taaacaaagc tatcaaacga aatagcatca taaaagcgca
    52801 tgaagccact aatattgcaa tggggcttca tgcctttttt aacctatcac acgttaagca
    52861 aagcaaaaag aggctaggac aaaaatcctt cctcttttaa aatcgtcaaa ctatagagtt
    52921 gattggaggg ctcttagccc tcatttttca agcgatgtgg cctttttaat cagctgctcg
    52981 agggtggata acctaatcaa catcgccagg tcatgacgat tgaatggtta ttccactctt
    53041 tttctacgct gagggctgtg aaagggctca tacgacagct tagccgcttt ctaacagcta
    53101 tttacctacc tcacctctta acgagcagac agcctaaatg gtatagtcca gctgatcaag
    53161 actcttttta tggtcaaggt caatatcaag aaaggtcatc tgcttgatat tgataaggct
    53221 ggctacaatt gataccggaa aagcaaccac cgcttgattg aagagactaa tattactatt
    53281 gacaatgcgt tttgctgctg ccaaggctgc attttcctta gcaatctcat tttgcaggct
    53341 caaaaactgc tcagaggagc gcatttccgg ataagcctct cctacagcaa aaacctcatt
    53401 caaggcctgc tcctgtgtcc tcatcacatc atttgtttcc tccaaggaaa gcccctgacg
    53461 cagcttcacg agttcagtaa agaccttttc ctcatgcttg gcataggact tagcgatttt
    53521 tagcatttcc gaaatggtat catatctctt ctcaagagca atatcgacat ttcgtttaga
    53581 ctcctctata acgattcgat acctttctaa tttgtttctc actccaataa gccatagtat
    53641 agtcatgcaa agaataagtg ttaacataga tgacgtcact gacataaaaa agcctcctta
    53701 aagctgatga tttagtgtat ccaacaagcg gtacatctta acaagcttgt cttgaatgtt
    53761 ttcatattcg ctacttaacg atagcttttc aatagcccct ctagagctag gggttttcaa
    53821 gagctgttga ccggaataga aggacacaac aacagtatca ccattcatat aaactgctac
    53881 aggcatctcc tctctccatt catcaagcac tgccagcata taaggattta agagcattct
    53941 agcgcttaat tcatctgtgc agtacacatt gtacgtttca ttaaagcgaa tgtcctccat
    54001 ttccagctgc acctcaccct ttagcttagc cttgtagcca ctatggacct tttctctgcc
    54061 caaaaagccc ttttgagtcg gcacaattct aatataaccc ttgatagctg tatgatattt
    54121 agccagcagc acctgtccgt taaaatcagt gacccgatgc cagttatcat cctcattttc
    54181 ctcatggtag gcataaagat tgcaaaattc tgtctgcatg tcatctccaa aaataatatg
    54241 gcaattactg tcataccatc tggaggacgg tgttgcaagc tttagtaagg agagctcaat
    54301 ccctgaatag taatctatct tgacatctgg cagggcctct tgtaaaacag gcagcaaaaa
    54361 gtgatccaca taggagagct catttgctgt tttgaatgtt ttcagccgcg gccaaaccaa
    54421 gccccccaca aagataatga gaaataaggc aagagatcgg tcaaccatgc catacaagat
    54481 gattgcgcct atcaccattg ccagccagcc cagattattc tttctagcat ttccactcat
    54541 ctcgctttta atttgctcca gcttttggtg atgctcaggc gaagcttcta tagctctact
    54601 cttctccaaa acaataggat ctgtcaatcg cttagtattt tcgttcatct cacttactcc
    54661 agatacttct ccatcagcag cgctcagctg ctcttgataa caccagtcac tttatgcttt
    54721 tgcttaacct ataaatgaca attgcgttac agctaattta taatattata ccatttttaa
    54781 actatttttt ctattattat atttaaatga cgctcaataa taaccacata atgttaatat
    54841 agacatcatt gtgctctttt ttacctaatc atgttgtgag caataccccc gtttatcagc
    54901 ggaaaccata aaggcctcta tgagatcaag actatcagcg ccagcccttc ttttggagtc
    54961 actattcagc ttgttcttcg catgctgtct ttgcctgacc atgattcagc tgctcttttt
    55021 gattgcttgt tatgctcact ttttccgtct catgctgagc aagaaaaaac agcaaaccct
    55081 tgcttggttt actgctcttc tgttgatgtt agtcaaaaaa taagccggga gctaatgaca
    55141 ccctattaac tcataaagcc tgttatcctt tctttgtcat agaacaattc acttagtcta
    55201 ttctcaacca aaatacgaag cctgcttaaa ccgtcttctc atattaacag ctaaaaagtg
    55261 gtgtcaatat gaagaaacct atgatcggta acaataatag cacctttaaa tctctcagcg
    55321 ataatgtaag gttatcctat acctgtcata tttttcggtg ctatttgcca tatcaggttg
    55381 ctatagcact tggtggcttc tggtagcctt aaccaataaa tgatctgctt ttttattcct
    55441 gctctttgtt ttgtttatgc cttttgtcgg cgcaggcctt tagctttact atactgacgg
    55501 taaggtcggt gagagccttt accatttttt atgccttaat cgcaaagcat ttaacaccac
    55561 tgatattgag ctaaggctca tcgcaaagcc agccagcatt gggcttaata gagggccgcc
    55621 aaagacatga aggataccca tagcaacggg gatcattagg ctattatagc taaacgccca
    55681 aaataaattt tgcttaacca ctctgatggt ttgacgactg agctctaggc attccaccac
    55741 atcacgcact gctgaggtca tcaggataac atctgccgcc tcaatcgcaa tatccgtacc
    55801 tgagcctatt gagattccaa tatccgctag ggtcaaggcc ggtgcgtcgt tgattccatc
    55861 accaaccata gcaaccagct gtccgctagc cttcaaatcc gcgataatct gggccttttg
    55921 agcaggcagc acctgactaa agacctgatc aattcccacc tcattagcaa tcgcttgagc
    55981 tgtgagggca ttatctcctg ttagcataac cgtttgaaga cctaaatcct gcaaggccct
    56041 tatagctgcc ttactgtcag cctttagcct atcagcaatc agcaataaag cacatagctg
    56101 attatccttg gcataataca ctacggtttg cccctttaag gcagcttgct cggcataggt
    56161 ctgagcagcg cttatcgcaa tcccctgctg tgacatcagc tcactattgc caacagctaa
    56221 gcgatgctgg tcaatcacac cagtgacacc caagcccaca agcgattgaa aatcagtcac
    56281 agccagcaag tcatagccct tttcctgtgc tactctaaca agcgcttctc caagagggtg
    56341 ctgcgaatac tgctctaagg aagccacctc ctgaagtccc tgcttctcac tagcagcaag
    56401 ggggatgatc cgctgtagct gagcctgacc ctctgtcagc gttcctgttt tatcaaaaac
    56461 aattgtccgc acctgataag ccttctctaa aatatctcct cccttaaaaa ggatcccctg
    56521 ctcagctgca cgacctgagc caaccataat cgcggtggga gttgctagac ccagagcaca
    56581 gggacaagca ataatcaaaa cagctatagc tattgtcagg gcaaaatcaa agctctctct
    56641 cataacaaag agccaaaaaa gaaagctcag cagggataaa cttaatacga tagggacaaa
    56701 gactcctgat accctatcag caagtgcagc aatcggagcc ttggcttgct gtgcttgctc
    56761 caccagctca ataatctgtg aaagcaaggt gtcattgcca agcctagagg gctttaccct
    56821 tagcgctcct tggccattga ttgtgccagc aaacacacta tcacctgtca ccttatcaac
    56881 tggtaggctt tctcctgtta gcatggactc atcaaccgta gactgcccct ctactatcag
    56941 cccatcaaca gccacccgtt cacccggttg aataaagcaa atatcctcat tagtcacctg
    57001 ctctaaggga ataagctgaa gtgctccctc acgaataacc ctgacatcag ttacccttaa
    57061 ggacattagc ttctgaatag cctgcgaggc ccgtcccttg gtacgcccct ccaaatagct
    57121 gccaagggta atcaaggtca gaataaccac aacagattca aaataaagct ggtgagcaaa
    57181 ttgagcagct ccagctacaa tcttaaaaca gctatatgag ctgtaaataa aagcaaagct
    57241 agtggctaag gtcacaagcg aatccatatt aggccgcttc tttatcaatg ccttaaagcc
    57301 attttcatag tactgccgat tcaagaaaag aacaggcagg gtcagcaaaa gctgaacaag
    57361 accatagctt atagcatgcg actgaggtgc tagagcgacc ggcagcacca atccaagcat
    57421 aggtcccatt gcaaggtata gcagcggcag actaaagaga gcagaccaca gaaagcgata
    57481 ccattcattg ctagcctgct cctctaggcg ctctagttgc cctctcatat tggtctcatc
    57541 aagcagctct gctctgtagc ctgcctttct tactgcttga atgagctctg ctgagctgag
    57601 gctgtcagtt gagtagctca ctgatagctt ctcagtcgtc acatcaacag ctgccccctc
    57661 aacacctggc agttgcttaa cagcctgttc aatcgctaga gcacaggagg tgcagtgcat
    57721 tccctctaat agataggtct ctttaacaat catatcctct cctttttctg acaatgacat
    57781 tgtcctggca cacaatcaca ccttacatgg gatactgctc cgactttttt agcctctaag
    57841 agcaactgaa aagcctgaat atcttccagg gtcattgggg tatcctttag taatgccagc
    57901 aacaagcggc tatggtggcg ttgacacatg ccatcaagcc tctctcgtag catagcaagc
    57961 tgtcgcctgt cctgatcaag caaggactgg taaatatagg accgtccctg tctatcagcc
    58021 cttagggctt ttttcttaac caagcgtcca atcaaggtct taacggtaga atcagaccaa
    58081 tggtgctttt catgaagaat agcaataatc tcagagctct tcatgctccc attagcccaa
    58141 acaacacgca taacctccca ttctgcatca gatatcgtat ccatattgct acctctcttt
    58201 catctacggt tttattaagt atagcttatt tgtttacgtt tgtaaacaaa taataactaa
    58261 aaaaggtctc tttatgagaa acagcgtcaa aaaaggactg acagctaaag tcagcagcta
    58321 gcttttaata gtctgaactt tccagtctta tctgattaac tttatattga caaaatgagt
    58381 ccttgtatat tactatatga cagtaatact gtaatgatta aggagaaaac attgacgtat
    58441 cttaaaagac agctaattct actagccctt ctactcacag ctataggtag ccaaacaatc
    58501 gttcaggcca gcacgcgatc ctggaaaagc tggtttattg agcaatattt ttggcttaaa
    58561 cgagacaaaa gctattatgc cgagcaggat gagaatacct tctacaacta cgtcaagtca
    58621 gctggtgaaa agagcaatca aggctttaat ctcactcaaa atgaggtcaa cggaacatta
    58681 aagacagagt atagagacaa catgcaggtt cacagctgga atgaaaactc tactaatcca
    58741 tcaaatcaaa aggtcattct ctatctgcat ggtggctcct acctaaacaa cccgacctca
    58801 taccatattg acatgctcaa aaccttgtca actagccttg atgctaagat tgtattgccg
    58861 atttacccaa aggctccgac ctatacctat gatgtcgcta tgccaagatt agttagtctt
    58921 tatcaggata ttctaaaaag cactaataac aatgctaaca atatcaccat catgggagac
    58981 tcagccggag gcggtctggc actaggtttg gcactagcat tgaaaaatga agatattaag
    59041 cagcctaagg acattatcct gctctcacct tggcttgatg tcaccctatc aaatccagag
    59101 atcccaaatt acgaagcctc tgatcctatc ttatcggctt ggggactgcg catagtaggt
    59161 gatatctggg cacgacgcgg ggaaaataac actaagcacc cttatgttag ccctatctat
    59221 ggagatacaa gcaacctagc acctatcacc atgtttgtag gaactcatga aatcttctac
    59281 ccagacatta caaaatttga tggtatgtta aaacaaaaag gacataagca ccagctattt
    59341 gtcggggaaa agatgaacca tgtttatcct atttacccga ttgaagaggc caagacagca
    59401 caataccaaa tcattgatac cataaaaaaa gagtacgaac cccaaaaata ataatacaaa
    59461 aatgcctacc agacttgagt tttttgccaa agcctggtag gcattttctg atcacagcat
    59521 gactactgtt tcttttctag ctcacggagc aattgatcaa ttttattacc ataggcgata
    59581 gaattgtcct tttcaaaaac caaatccgga attttataca tggttaattg cttaccaagc
    59641 tcacgcttaa tggttcctgt tgcttttttt aagcctattt cagccttttg attgtctgaa
    59701 gctaggtcac tcataatggt atagtaaacc ttagcaactg acaaatcgcc cagcatttgc
    59761 acttctgtga tcgtaacacc ctgcacacgt ggatcacgaa cctttttgtg taaaatctcg
    59821 ttgacctcac gcttgatttc cataccaaca cgatcaatac gatgatttgt catggccctt
    59881 cctttctatt gtcaaatagt acaggctctc agtagctcaa taacaagaga aaagcttgat
    59941 gactttcaag cctttttctc tattaggctg atggctatac tattaatagt gactgttcaa
    60001 atcaagtggt gacattgtct attgtcttga gacgaggcta tttaagctac tagccaccac
    60061 gattatttac gggtaatttc ttccatgacg taagcctcaa tggtatcatc gaccttaatg
    60121 tcattaaagc cttcaatcat caaaccaccc tcttgggcat tcccaatctc cttaacatcg
    60181 tccttataat gcttaagact ggctagctta ccatcaaaga taaccacgct atcacgaatg
    60241 acacgtacac ttgaatcacg cgttacctta ccattaacaa ccataaagcc tccgattgtc
    60301 ccaaccttag agaccttaaa ggtttcacga ataatagcct caccaagcat tttttcttga
    60361 tactcagggt caagcttacc tttcatggct tcctcaacct cttcgatcac cttataaata
    60421 atgctatgca agcgaatctc aacatcgtct gtatcagcct gctgacgcgc ctgtggtgtt
    60481 ggacgcacat tgaagcctat gataacagcg tttgaagcct ctgccaaggt cacatctgac
    60541 tcattgatcg caccgacagc agagtgaaca acatttactc gaacgccctc aacatcaatt
    60601 ttaaggagtg aggctgccaa agcttccaca gagccctgca cgtctgcctt gatgatcacg
    60661 ttaacggttt tgatttcccc tgccttgagg gtatcaaata ggttatcaag gctgacacgc
    60721 tgcgtgtttt gacgttgctt gagaagggca cgcttagcac gctcctcccc tgctgcacgc
    60781 gctgcttttt catcagcata gaccgcaaaa tgatcacccg ccataggggt ttcattgaga
    60841 ccagtaatag ataccggtgt ggacggctca gctgatttca cacgacgacc aaggtcattt
    60901 gtcatggcac gcacacgacc aaaggtgtta ccaacaacga ttgggtcttg tacgtgtagg
    60961 gttccttgtt ggaccagaag tgtcgcaacc gcacccttac ctttgtcaag tctagcctca
    61021 atgaccgtac caatcgcacg aaccgtagga tcagccttta gctcttcaac ctcagctacc
    61081 aaaagcactg tttctagcag ctcatcaatg tttttgttaa atttggcaga gatttcaaca
    61141 aactcacact caccacccca agcagttgag atgatcccat gctcagccaa ttctgaaata
    61201 acacgctcag gattagcccc tggcttgtca atcttgttga tggcaacgat aattggaaca
    61261 ccagccgcct tagaatggtt aatagcttca atggtttgtg gcattacccc gtcatcagca
    61321 gctacaatca aaatggtaat atctgtcact gacgctccac gtgcacgcat gcttgtgaag
    61381 gcagcatgtc ctggtgtatc caagaaggta atcttcttgc ctgcctcctc aatctggtaa
    61441 gctccaatat gctgggtgat ccctcctgct tctcctgttg caacacgaga atttctaagg
    61501 gtatcaagca gggtcgtctt accatgatcg acgtgtccca taatggtaac aaccggtgca
    61561 cgctcaacaa tattctcagg attaaggtag ctatcatcag taaagaagcg ctcgatatca
    61621 gcttcatcaa cctccacctt ggccttagct tcaatgccat aatccaccat taagagctca
    61681 atggtatcac catctaagga ttggttttgc gttgccatca cacccatcat aaataatttc
    61741 ttgacaatct cagccggctc acgcttgatc cgttttgcaa tttcagcaac ggtcattcct
    61801 tctgaatatt caaattcttt tggtaattca tggaatttac gctctgttac tggttttgga
    61861 gctgtgttgc tattcttatg atgcttacct tttttgtttt tcttgttgtt attccagtta
    61921 ctattctttt gatttctcac ttggttttga ctattccaac tcttcttatt tttcttttgt
    61981 ccatcttcta ggccatgatc ccgatcatgc cctttgtctg gacgattttg ttttttacga
    62041 cgcttatcaa ccggttttgc taccgatgca gcagccatac tagcaaccga ctcagtagcc
    62101 ttagctgagg cttcacgatg ctttttgtcc tctgtctgag ccttgagggc ggctgcctta
    62161 gcctcttgcc ttgcctgttg ctctaagcgt ttagcctcct cttgctcacg aaagcgtgat
    62221 tccctttgtc tggcatactc tgcgttttgc tcagccttta aggcagcagc acgcgcctta
    62281 aaatcaatct taggagcacc ggcttgggtc tgcccttgac gtcctgtatc ctgttgacga
    62341 ctattagcgt taaaggaacg gtttttgtca cgattaccag cttgtctatg cccatcgttt
    62401 cggttatttc cagatgatgg cctgttatca aagcgtctat ctctttgctg attttgtgac
    62461 ttgtggccag ctcgctccgt ctgctgacct tgtgatcgtc caagttgacg atagtctgac
    62521 ttgcggtcat tagagcgatt ttgcccagcc tgccgtctcg ctacctgctc cttggcacgt
    62581 gcttcacgct ctgccttgaa attgcggctc tttggcttaa cagcaaccgg ctgtgatgct
    62641 tcttgtgtcg cagcagctgg cttttctgct gctttagagg ctgctggctg tggtgtagtg
    62701 gccttagctg cttttgcttt ttgttctgct acttgcttgt cttttgctga acctgcttga
    62761 acattcttag tcacacctgc tgaaaagcta gaggcaattt tgttagcatc tgcttcttcg
    62821 acgcttgacg catggctttt gacatctaat cctaaggatt tagcacgctc aacgacttct
    62881 ttactacttt tgccaatttc cttggcaatt tcatgtaatc ttttctttga caatttgtgt
    62941 cctcctattc gtctatttca taagagtcct cattttcttt gaaaatccag cgtctgcaat
    63001 ggcaaccacc ttacgaggct tgccaagtgc agcacttaat tccagtgcac taaacactgt
    63061 ggagacttct acattgtaat aattactttt atctgttact tttttagtga tatttgggcc
    63121 agcatcattg gctaaaaaaa caagattgac ttcctgatgt cgaatggctt taatgaccaa
    63181 ttcctcacct gaaatcactt ttttggcccg ctgagccagt ccgatcaaat gagataatct
    63241 atttaaacta ttcaaggcct agctctcttc ttttaacttt gtgatcaaca tgtgcaatca
    63301 cttcatcgta aaagctctct ggcacctcca ttgagaagct acgattaaac acctgttttt
    63361 tctttgccat aagtgcttct tggttatcta gcttgatata agcaccacgc ccattttgct
    63421 tgccggttgg atcaataaaa atctgcccct ccttattttt gacaatacga aggaggtcac
    63481 gcttatcaat gatctcacca gaaacaagcg acttacgtaa aggtattttt tttactttag
    63541 gcataaaaca cctcttttct tacacttcct cgttggttaa gagctcctct gtagctactg
    63601 cttcagtcat tgctgcttct ttttctgctt caaggcgttc atattcactg gctgatttga
    63661 tgtcaatgcg atagcctgtc aaatgagctg ccaaacgaac gttttgacca cgacgaccaa
    63721 tagcaagcga tagcttatta tcaggcacca ccacagtcgc acgcttaaga tcgtcatcat
    63781 caaagagaac catatcaacc tcagcaggtg caatggcatt gtagataaat tcagcagggt
    63841 catctaccca ttggataacg tcaatatttt cttctactgg gatctcaagt cctgtcttag
    63901 catcatagcg ctttggatgg aatttactga taaccttttt gatgttgctg ccgccacgac
    63961 caacaatcgt tccaatcgca tcaacattgg gattgtggct acgcacagca accttagtac
    64021 ggtcaccagc ctcacgagaa acactcataa tctcaacggt cccatcaaaa acctctggaa
    64081 tttcctgttc cataatgcgc ttgatgaact cagggtgact acgactaaca aagacgttaa
    64141 ccccctttgg attgttttcc accttgtaga catagacatc aatccgatca tgtgatttga
    64201 aggtttctcc tgggatttga tcctgatgtg agagctgagc ctctaaggaa ccaaggttaa
    64261 cataaatgaa acgttggtca aaacgctcaa ccgtacccgt catgatttca ccttcatgct
    64321 gcttgtactc attgaaggtg atttctcgca tctgacgacg catcctttcc ataatggttt
    64381 gctttgcaga ttgagcagcc acacgtccaa actcgctgac tgattcttca aaacgaatct
    64441 tatctcctaa ctcataggct gagctaatgg caagggcatc gttcaggcta atttccagac
    64501 ggctatcaaa tacctcttca acaacctcac gaaccgtaaa aacctgaaaa tctgctgttt
    64561 tatcattaaa ttcaatgacg caggattctg cttgaccata acgacgttta taagctgatt
    64621 tcagtgattc agtgactgcc tcaatgatat ctgccttatc aatgtgtttt tcttcttcca
    64681 aaatacggaa ggcttctagc atttctttgc tcataatgtt gtctaccttg ctctcaaagc
    64741 ttggtaaaaa tcctttctta tcttataaat taatccattt agggcttagc caaccgacta
    64801 aagcaaatcg ctcagcaatt gccttataat ttgacagcta aacgagcctt agccactgct
    64861 tggtaaggaa tctcaactgt tttgtgacgc gtcttatcta gataatcaat ggttagggta
    64921 tcaccatcaa aagccactaa atctccttga aaaaccttca ccttatcaat tgcccgatag
    64981 aggctgacat taatatatga gcctacagca gccttcaagc tctcagcagt ctttaatgga
    65041 cgctctagcc caggactgga aacctccagc atatactgat ctgggaaagg gtctggagaa
    65101 atcgtatcta agagtggact gattagctct gtaagctcag cagtatcctc aacggtaatc
    65161 ccagaagcct tatcaactaa gatactaagg acataatcat tgcccatttt gtcgtattcg
    65221 atgtcgacca attcataggg tgctttaatt acaggttcta cgatttgggt aacaatatca
    65281 ataatagctg tgtttgcgat gttaataacc tcctttactg atgactgcta tacctctata
    65341 gccttgtcct cttgataatc aacacaaaag tggcgagata tttctcacca cccttctgta
    65401 ttgctttaac ctattatacc acaatcaaaa tgaattgcaa gaaaatccct actaaaagtg
    65461 tcaataagac ctcaaaaatc ctatttttta aaaggagagg agatctttaa ccttgctttt
    65521 ttctctttcc ttatcccctc taacctctgt attcatatga taaaataaaa tattaaaggg
    65581 taaaaaagac aactaaaata ttatttgcgg ctgcttcatg gtctttacca aaacgaaaaa
    65641 acctcccatc agaacagatc tatgcatatg cgagagaggc cattggtaac tcaataacat
    65701 cattaataaa gcttaaatta gttcaatttg taattttaat accactattt atcggtaata
    65761 taagtttatc tgaggatatt aaaaatatta atgctatttt taaagacagc attagttaat
    65821 gatataataa aagctgtaat ctccctcatt atatcataaa aacgatttca aaaacagact
    65881 tgtatttcaa gtgacatttg atatacttga agatgggaat actgcttgag tggaggcatt
    65941 gtaggtctag ttcaacgtaa agcagcagct gaaatcgcaa aactaatact taaagtgggg
    66001 atcaagaatg tagcccctgc tgcagctgca gcatcattaa tttggagctt tggaagatgc
    66061 atgtggtttt aatgtcaaaa agatatagta tttgtataac atttcttgtt attatttcgc
    66121 gattcgtttg gtttgccctt acaggaagaa gtccttttta tgactttatt gggactatat
    66181 ttttaggagt agtggtttta ctaattagtc aaaaagtatt gaaaaaatta aagtgataaa
    66241 attattaacc cgacaatagc gaagcagaat gtgatattat tgatatgttc cataagatac
    66301 tttctaatga gattgttagt gcttctcatg ataagtctta tgggactttt ttgtactcaa
    66361 aaagccctat catttccata ctggataaat ccactacaga aatgatagag cctaaaatat
    66421 atgttcacca attggataag ttaaaagaaa aaaatgacca tcaggtcaaa agcatttttc
    66481 aaaatctcaa atttgacggg tgaaaaacag gcgaagactc cgaaaccctt gatataccaa
    66541 taggataaaa ggagaggagg ggattgctgg tggttatttc accgttttca acctttgcaa
    66601 aacacttaaa cgttggtgtt ttgagaatat aaaaaggata gaaaaagacg aaaaaacaaa
    66661 aataaacggg tgattgacgg gtaatgttac tccaattccc gcagcacttc ttccactatt
    66721 tcttctattg acacctccca cgacctcact tcctcatgcg gcaatacata atcaaaaatc
    66781 tgtccgtttt tgcgcacgat cgctactgtg tctcctgtga tatatccgtc atcaattgcc
    66841 tgtttaaatt cgtcgtatgt tagcataaag cacctcctta tcttattatt cgtattttac
    66901 aggaaataat ataattaaat ttaaagctt
//
LOCUS       DARYJX010000005        63570 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYJX010000005 DARYJX010000000
VERSION     DARYJX010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63570
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            16..100
                     /locus_tag="TU257_000280"
     tRNA            16..100
                     /locus_tag="TU257_000280"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:50..52,aa:Leu,seq:taa)
     gene            115..188
                     /locus_tag="TU257_000281"
     tRNA            115..188
                     /locus_tag="TU257_000281"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:149..151,aa:Arg,seq:acg)
     gene            195..268
                     /locus_tag="TU257_000282"
     tRNA            195..268
                     /locus_tag="TU257_000282"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:229..231,aa:Pro,seq:tgg)
     gene            279..352
                     /locus_tag="TU257_000283"
     tRNA            279..352
                     /locus_tag="TU257_000283"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:313..315,aa:Met,seq:cat)
     gene            373..446
                     /locus_tag="TU257_000284"
     tRNA            373..446
                     /locus_tag="TU257_000284"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:407..409,aa:Ile,seq:cat)
     gene            454..543
                     /locus_tag="TU257_000285"
     tRNA            454..543
                     /locus_tag="TU257_000285"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Ser,seq:tga)
     gene            555..628
                     /locus_tag="TU257_000286"
     tRNA            555..628
                     /locus_tag="TU257_000286"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:589..591,aa:Met,seq:cat)
     gene            653..725
                     /locus_tag="TU257_000287"
     tRNA            653..725
                     /locus_tag="TU257_000287"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:686..688,aa:Phe,seq:gaa)
     gene            731..801
                     /locus_tag="TU257_000288"
     tRNA            731..801
                     /locus_tag="TU257_000288"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:763..765,aa:Gly,seq:tcc)
     gene            831..904
                     /locus_tag="TU257_000289"
     tRNA            831..904
                     /locus_tag="TU257_000289"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:865..867,aa:Ile,seq:gat)
     gene            914..1001
                     /locus_tag="TU257_000290"
     tRNA            914..1001
                     /locus_tag="TU257_000290"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:948..950,aa:Ser,seq:gct)
     gene            1060..1875
                     /locus_tag="TU257_000291"
     CDS             1060..1875
                     /locus_tag="TU257_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL0833341.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            1878..2381
                     /gene="mreD"
                     /locus_tag="TU257_000292"
     CDS             1878..2381
                     /gene="mreD"
                     /locus_tag="TU257_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL0833342.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2477..3655
                     /locus_tag="TU257_000293"
     CDS             2477..3655
                     /locus_tag="TU257_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0833343.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            3760..4722
                     /locus_tag="TU257_000294"
     CDS             3760..4722
                     /locus_tag="TU257_000294"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0833344.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            5082..5852
                     /gene="recO"
                     /locus_tag="TU257_000295"
     CDS             5082..5852
                     /gene="recO"
                     /locus_tag="TU257_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL0833345.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5968..6975
                     /gene="plsX"
                     /locus_tag="TU257_000296"
     CDS             5968..6975
                     /gene="plsX"
                     /locus_tag="TU257_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL0833346.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6968..7216
                     /locus_tag="TU257_000297"
     CDS             6968..7216
                     /locus_tag="TU257_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0833347.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            7366..8076
                     /locus_tag="TU257_000298"
     CDS             7366..8076
                     /locus_tag="TU257_000298"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL0833348.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            8255..11995
                     /locus_tag="TU257_000299"
     CDS             8255..11995
                     /locus_tag="TU257_000299"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL0833349.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAENLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            12114..13571
                     /locus_tag="TU257_000300"
     CDS             12114..13571
                     /locus_tag="TU257_000300"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL0833350.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            13628..14650
                     /locus_tag="TU257_000301"
     CDS             13628..14650
                     /locus_tag="TU257_000301"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL0833351.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            14647..15204
                     /gene="purN"
                     /locus_tag="TU257_000302"
     CDS             14647..15204
                     /gene="purN"
                     /locus_tag="TU257_000302"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL0833352.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            15351..16898
                     /gene="purH"
                     /locus_tag="TU257_000303"
     CDS             15351..16898
                     /gene="purH"
                     /locus_tag="TU257_000303"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL0833353.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(17276..18430)
                     /locus_tag="TU257_000304"
     CDS             complement(17276..18430)
                     /locus_tag="TU257_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL0833354.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            18821..20083
                     /gene="purD"
                     /locus_tag="TU257_000305"
     CDS             18821..20083
                     /gene="purD"
                     /locus_tag="TU257_000305"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL0833355.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            20312..20800
                     /gene="purE"
                     /locus_tag="TU257_000306"
     CDS             20312..20800
                     /gene="purE"
                     /locus_tag="TU257_000306"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL0833356.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            20787..21860
                     /gene="purK"
                     /locus_tag="TU257_000307"
     CDS             20787..21860
                     /gene="purK"
                     /locus_tag="TU257_000307"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL0833357.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            21875..22099
                     /locus_tag="TU257_000308"
     CDS             21875..22099
                     /locus_tag="TU257_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL0833358.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            22696..23988
                     /gene="purB"
                     /locus_tag="TU257_000309"
     CDS             22696..23988
                     /gene="purB"
                     /locus_tag="TU257_000309"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL0833359.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            24286..25199
                     /locus_tag="TU257_000310"
                     /pseudo
     CDS             24286..25199
                     /locus_tag="TU257_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25282..25380
                     /locus_tag="TU257_000311"
     CDS             25282..25380
                     /locus_tag="TU257_000311"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL0833360.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            25414..26421
                     /gene="ruvB"
                     /locus_tag="TU257_000312"
     CDS             25414..26421
                     /gene="ruvB"
                     /locus_tag="TU257_000312"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL0833361.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            26662..27120
                     /locus_tag="TU257_000313"
     CDS             26662..27120
                     /locus_tag="TU257_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL0833362.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            27126..27527
                     /locus_tag="TU257_000314"
     CDS             27126..27527
                     /locus_tag="TU257_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833363.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            27524..29305
                     /locus_tag="TU257_000315"
     CDS             27524..29305
                     /locus_tag="TU257_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL0833364.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            29725..32367
                     /gene="adhE"
                     /locus_tag="TU257_000316"
                     /gene_synonym="adhC"
     CDS             29725..32367
                     /gene="adhE"
                     /locus_tag="TU257_000316"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL0833365.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            32862..33914
                     /locus_tag="TU257_000317"
     CDS             32862..33914
                     /locus_tag="TU257_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL0833366.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            34117..35133
                     /gene="adhP"
                     /locus_tag="TU257_000318"
     CDS             34117..35133
                     /gene="adhP"
                     /locus_tag="TU257_000318"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL0833367.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            35849..37441
                     /locus_tag="TU257_000319"
     CDS             35849..37441
                     /locus_tag="TU257_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833368.1"
                     /translation="MKEIVRSHRLLYVIVAFFSVISAFLMTLFSIQLGKILDSISNSS
                     SELLFQIVVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLLREFNEIDTC
                     DRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWRLALVFLLLS
                     IVTVFLSQIPGKLMSKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNT
                     TLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLL
                     NGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEGDISSISINN
                     LTYQVENRKIFTNFSFEFKKGNTYAIIGPSGVGKTTLAKLILNYYPKHLYDGEIRIDG
                     RNIAEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLNLTDKLKDSLGFDETFLNK
                     KLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTGNLDPARSKAILDYILSIKNAI
                     IIVITHNQDIKTLEQFDEVICL"
     gene            37604..38726
                     /locus_tag="TU257_000320"
                     /pseudo
     CDS             37604..38726
                     /locus_tag="TU257_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            38719..39894
                     /locus_tag="TU257_000321"
     CDS             38719..39894
                     /locus_tag="TU257_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0833369.1"
                     /translation="MNKKIIFKGDQDSKFAYFSLMFSAGTAIENTEELGFSHLIEHLL
                     LRSGGEQSLNELFDNNGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTE
                     EELLREKRVVLVELTQYENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKL
                     YKFYTENIQNGEFQIAISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKN
                     QQVSEISMYIDISKMTTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFP
                     IFYNGLTILKILTRTPEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSY
                     EVKKVEFLKTLCREKLFNIPSWESVTGEIEKVSLNELNQFAKDALMQNKQFHIIINC"
     gene            complement(39878..40741)
                     /locus_tag="TU257_000322"
     CDS             complement(39878..40741)
                     /locus_tag="TU257_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0833370.1"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKLGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISGLDNNHQLTNQDISYLSNYLFSLENWGYYETLILGNCC
                     RSLPPKLLFKYTKEALKKGKLYNSIPRNKQSLIQLLLNSLLLMIENDFYEEAIFLNQA
                     SKNLLSNSTYFFELTILLYLEGYLELKFNIHTEKSNSKIEEALKIFNSLNKTIYQNYQ
                     EHFNKYISNLL"
     gene            41377..42861
                     /locus_tag="TU257_000323"
     CDS             41377..42861
                     /locus_tag="TU257_000323"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL0833371.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            42901..44202
                     /locus_tag="TU257_000324"
     CDS             42901..44202
                     /locus_tag="TU257_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL0833372.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            44582..44890
                     /gene="rpsJ"
                     /locus_tag="TU257_000325"
     CDS             44582..44890
                     /gene="rpsJ"
                     /locus_tag="TU257_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL0833373.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHNYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            45188..45814
                     /gene="rplC"
                     /locus_tag="TU257_000326"
     CDS             45188..45814
                     /gene="rplC"
                     /locus_tag="TU257_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL0833374.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            45839..46462
                     /gene="rplD"
                     /locus_tag="TU257_000327"
     CDS             45839..46462
                     /gene="rplD"
                     /locus_tag="TU257_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL0833375.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            46462..46758
                     /locus_tag="TU257_000328"
     CDS             46462..46758
                     /locus_tag="TU257_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL0833376.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            46776..47609
                     /gene="rplB"
                     /locus_tag="TU257_000329"
     CDS             46776..47609
                     /gene="rplB"
                     /locus_tag="TU257_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL0833377.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            47721..47999
                     /gene="rpsS"
                     /locus_tag="TU257_000330"
     CDS             47721..47999
                     /gene="rpsS"
                     /locus_tag="TU257_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL0833378.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            48015..48359
                     /gene="rplV"
                     /locus_tag="TU257_000331"
     CDS             48015..48359
                     /gene="rplV"
                     /locus_tag="TU257_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL0833379.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            48372..49025
                     /gene="rpsC"
                     /locus_tag="TU257_000332"
     CDS             48372..49025
                     /gene="rpsC"
                     /locus_tag="TU257_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL0833380.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            49029..49442
                     /gene="rplP"
                     /locus_tag="TU257_000333"
     CDS             49029..49442
                     /gene="rplP"
                     /locus_tag="TU257_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL0833381.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            49452..49658
                     /locus_tag="TU257_000334"
     CDS             49452..49658
                     /locus_tag="TU257_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL0833382.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            49683..49946
                     /gene="rpsQ"
                     /locus_tag="TU257_000335"
     CDS             49683..49946
                     /gene="rpsQ"
                     /locus_tag="TU257_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL0833383.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            49971..50339
                     /gene="rplN"
                     /locus_tag="TU257_000336"
     CDS             49971..50339
                     /gene="rplN"
                     /locus_tag="TU257_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL0833384.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            50423..50728
                     /gene="rplX"
                     /locus_tag="TU257_000337"
     CDS             50423..50728
                     /gene="rplX"
                     /locus_tag="TU257_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL0833385.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            50752..51294
                     /gene="rplE"
                     /locus_tag="TU257_000338"
     CDS             50752..51294
                     /gene="rplE"
                     /locus_tag="TU257_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL0833386.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            51310..51495
                     /locus_tag="TU257_000339"
     CDS             51310..51495
                     /locus_tag="TU257_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL0833387.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            51828..52226
                     /gene="rpsH"
                     /locus_tag="TU257_000340"
     CDS             51828..52226
                     /gene="rpsH"
                     /locus_tag="TU257_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL0833388.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            52548..53084
                     /gene="rplF"
                     /locus_tag="TU257_000341"
     CDS             52548..53084
                     /gene="rplF"
                     /locus_tag="TU257_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL0833389.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            53187..53543
                     /gene="rplR"
                     /locus_tag="TU257_000342"
     CDS             53187..53543
                     /gene="rplR"
                     /locus_tag="TU257_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL0833390.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            53562..54056
                     /gene="rpsE"
                     /locus_tag="TU257_000343"
     CDS             53562..54056
                     /gene="rpsE"
                     /locus_tag="TU257_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL0833391.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            54071..54253
                     /gene="rpmD"
                     /locus_tag="TU257_000344"
     CDS             54071..54253
                     /gene="rpmD"
                     /locus_tag="TU257_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL0833392.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            54455..54895
                     /gene="rplO"
                     /locus_tag="TU257_000345"
     CDS             54455..54895
                     /gene="rplO"
                     /locus_tag="TU257_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL0833393.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            54912..56216
                     /gene="secY"
                     /locus_tag="TU257_000346"
     CDS             54912..56216
                     /gene="secY"
                     /locus_tag="TU257_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL0833394.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            56368..57009
                     /locus_tag="TU257_000347"
     CDS             56368..57009
                     /locus_tag="TU257_000347"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL0833395.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            57127..57345
                     /gene="infA"
                     /locus_tag="TU257_000348"
     CDS             57127..57345
                     /gene="infA"
                     /locus_tag="TU257_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL0833396.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            57371..57487
                     /gene="rpmJ"
                     /locus_tag="TU257_000349"
     CDS             57371..57487
                     /gene="rpmJ"
                     /locus_tag="TU257_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL0833397.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            57505..57870
                     /gene="rpsM"
                     /locus_tag="TU257_000350"
     CDS             57505..57870
                     /gene="rpsM"
                     /locus_tag="TU257_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL0833398.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            57888..58271
                     /gene="rpsK"
                     /locus_tag="TU257_000351"
     CDS             57888..58271
                     /gene="rpsK"
                     /locus_tag="TU257_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL0833399.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58318..59256
                     /locus_tag="TU257_000352"
     CDS             58318..59256
                     /locus_tag="TU257_000352"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL0833400.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            59271..59657
                     /gene="rplQ"
                     /locus_tag="TU257_000353"
     CDS             59271..59657
                     /gene="rplQ"
                     /locus_tag="TU257_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL0833401.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(59875..60106)
                     /locus_tag="TU257_000354"
                     /pseudo
     CDS             complement(59875..60106)
                     /locus_tag="TU257_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            60962..62212
                     /locus_tag="TU257_000355"
     CDS             60962..62212
                     /locus_tag="TU257_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833402.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            62202..63077
                     /locus_tag="TU257_000356"
                     /pseudo
     CDS             62202..63077
                     /locus_tag="TU257_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            63098..63391
                     /locus_tag="TU257_000357"
     CDS             63098..63391
                     /locus_tag="TU257_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0833403.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT        19033 a        11077 c        14380 g        19080 t
ORIGIN      
        1 gttcgctttt ggggagccgg ggtggcggaa ctggcagacg cacaggactt aaaatcctgc
       61 gatggttaac atcgtaccgg ttcgattccg gtcctcggca tagcataagg aaaagcaccc
      121 ttagctcaac tggatagagt acctgactac gaatcaggcg gttagaggtt cgactcctct
      181 agggtgcata gttacgggaa gtagctcagc ttggtagagt acttggtttg ggaccaaggt
      241 gtcgcaggtt cgaatcctgt cttcccgatt agtttgatgg cggtgtagct cagctggcta
      301 gagcgtccgg ttcatacccg ggaggtcggg ggttcgatcc ccttcgccgc tattttgttt
      361 ttggattgtt ttggaccttt agctcaactg gttagagcac tcggctcata accgagcggt
      421 cgtaggttcg agtcctacaa ggtccataat ggtggaggat tacccaagtc cggctgaagg
      481 gaacggtctt gaaaaccgtc aggcgtgtaa cagcgtgcgt gggttcgaat cccacatcct
      541 cctttaaaga ttatcgcggg atggagcagt taggtagctc gtcgggctca taacccgaag
      601 gtcgtaggtt caaatcctgc tcccgcaatt atataaaaga tatatgctgg ttggctcggt
      661 agctcagttg gtagagcaat ggattgaagc tccatgtgtc ggcggttcga ttccgtctcg
      721 cgccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct gttgtcgcga
      781 gttcgattct cgtcacccgc tttatagttt tcccaagcta tagtgtgctt gggcgcgtag
      841 ctcaggtggt tagagcgcac gcctgataag cgtgaggtcg gtggttcgag tccactcgtg
      901 cccatcatta tttggagaat tactcaagag gctgaagagg acggtttgct aaatcgttag
      961 gtcgggtaac tggcgcaagg gttcgaatcc cttattctcc gtattgtaaa ggtgattatc
     1021 atactgataa tcgttttttt atttttagag gtgattttat tgaaaaagct taacctatct
     1081 cgtctctttt tttggttaac atcattagct ttactggctt tgaccttggt tcttcttttt
     1141 agagtagcta tttctccata tttatcaatg attatccgaa atcccgttac aaaaattgat
     1201 gctataatgt ctaagccttt tgctgttata aaggagggtg caaaggaatt agatagcttg
     1261 atgtctgctt tttctgaaaa taagcattta aaaaaggaac ttaggtccta taaattggat
     1321 cagttacagg ttgacaagct aaaatctgaa aatcgagagc tcaaggaact gttagggttg
     1381 gattatggta ctgataatca atttgctgcc agaatgatat caagaaatcc ttatagctgg
     1441 aataaatcgc tggtcattga tagcggcaaa agggaaatta aggagaagtc tttggttact
     1501 tcagagcttg gacttattgg tcgtgttaca gctgttagcc agtcatctgc tcatgttgaa
     1561 ttgttaacat ctgggaagaa tattgagttg ccgattaaaa ttgtagataa ggataaggtg
     1621 atttatggca atttaaaggc atttaaatca gaaagtaaaa caatggttgc cagcgaattt
     1681 aattctaatg actcaatatc attagatgct aaggtttata caagtggatt agatggtgag
     1741 actgtggcag atattcctgt tggaaaggtt acgggcttta aaaatgctgc tgataagcta
     1801 aagcgtcgta tttttataaa attgtatgct gatactgata atcttgacta tgttcttgtt
     1861 gttggaaaag agtgaatatg aaaaaatctt cagagctatt agtccttttg ccttttcttt
     1921 tattttttgt tgatgcacac gtgtcagacc tgatcagctc aatgttacct gagggttact
     1981 cggtagtatc acacctcttt ttactgtttt tcctgatcct tatggtagcg tttagatcta
     2041 agggagttat ttgtttcttc tctcttcttt taggattatt gtttgattat tattattttg
     2101 atcatatagg gattttgtct cttgccttgc cttttggaac aatgatcgtt ctagggctat
     2161 taaggttctt ttctggttcc attagtcagc tacaattttt ccttttcttt actctttata
     2221 tgtttcttgt agatgtatca agctttattt tggcaaacag ctatcagtta actgatatga
     2281 cttttcctta tgtaatgacg tttcagcttg ctccgacttt aatcgtcaat ctccttattt
     2341 tgttttgctt tagaaaatta atattaagtc aattttattg attattacat acaactgtaa
     2401 cagatgcgta acattaaacg cttgattttt tgatagaata taatgtgtct tatcgaaaag
     2461 gagtaatttt tttagtatga aaaaaagaat tctatcagcg gttcttgtaa gcggtgtgac
     2521 ccttggaaca gcaactacag tgggagcgga tgatttagat tccaaaatag cgttgcaaaa
     2581 ttcagttatt tctaatttaa ataaagaaca aaaagctgcg caggatagaa tgaagacttt
     2641 gcaaagtcag gttagctcat tacaatctga acaagaaagg ttagtcgcta aaaatggtga
     2701 gcttgaagcg cgatctgctc agtttgagca ggagattcaa gtgcttgcca gtcaaattat
     2761 tgctcgtaat gaaaagttaa aaggacaggc tcgtagtgct caaaagggaa atacgttagg
     2821 ttacctcaat gcacttttga attctaagtc aatttctgac gttattactc gtttggttgc
     2881 tattaataga gctgtgtcag ccaatgcaca gatgttggaa aagcaaaagg ctgataagct
     2941 ttctcttgaa gaaaagcaac aggaaaatca agaagcgatt aatacaattg cttcaaatat
     3001 tacagcaatt gaatcaaacc aagtagcttt aaagactcaa caagcagatt tagaggttgc
     3061 caaggtagat ttggcgcttc aattagcaac tgctgaggac gagaaggcta gcttgattac
     3121 ccgtaaagag gctgcagagc aggcagcagc tcaagccaag gctcaggcag agcaggaagc
     3181 agcagccaga gcagcacagg ctcaagctca agcacagtct gtagcggcag ctcaagcagc
     3241 agtgactcaa gccgtaccaa caccagctcc agcgcaggca cagcctgttg tggcgccagc
     3301 agctatggtt tcaacaccag cggtgtcgta tgcctatgat ccttctaatc cgtaccctgt
     3361 cggccaatgt acttggggag ttaaggcttt agctccttgg gttggcaatt attggggaaa
     3421 tggtggtcaa tgggcatcaa gtgcagcggc agcaggtttc cgtgtaggtg caacaccaat
     3481 ggttggctct gttgttgtat ggaatgatgg tggctatggt cacgttgcct acgtaacagg
     3541 tgttcagggt ggacagattc aagttatgga agccaactat gctggaaatc aatctattgg
     3601 caattatcgt ggttggttta gcccaggtgc tgtatcgtat atttatccaa attagaaaat
     3661 aagtaaaggt aagaatcagg attcttacct ttttatttcc attgaaaaat tgattgaaaa
     3721 gggttaaaat ggtataggat caaaactttg gaggaaaaaa tgtcttattc tgatttaaag
     3781 ctgtttgcat tatcgtcaaa caaggaatta gcagaaaaag ttgctgctgc gatgggaatt
     3841 caacttggga agtctacggt tcgccagttt tcagatggtg agattcaggt caatattgag
     3901 gaatcaatac gtggacacca tgtttttatt ttgcagtcaa caagctcgcc tgttaatgat
     3961 aacctaatgg aaattttaat tatggttgat gctttaaagc gtgccagtgc tgagaaaatt
     4021 tctgtggtaa tgccttatta tggctatgct cgtcaggatc gtaaggctcg ttcgcgtgag
     4081 cctattacct ctaaattagt cgctaatatg ctagaggtgg caggtgttga tcgtttattg
     4141 actgttgatt tacatgctgc gcagattcaa ggcttctttg atattcctgt tgatcatctc
     4201 atgggagcac ctttaattgc tgattatttt gatcgtcatg gtctagtagg tgatgacgtt
     4261 gttgttgtta gcccagatca tggtggtgtg acgcgtgctc gtaagctggc acaattcctc
     4321 caaacgccaa ttgctattat tgataagcgt cgtagtgttg ataaaatgaa taccagtgag
     4381 gtgatgaata tcattggtag tgttgaaggt aaaaaatgta ttctgattga tgatatgatt
     4441 gatactgctg gtaccatctg tcatgccgct gatgcgcttg ctgaagcagg agcaacagca
     4501 gtttacgcat catgtactca cccagtgctg tcaggaccag ctcttgataa tattcaaaaa
     4561 tcagcgattg aaaaattgat tgttttggat acgatctatt taccagaaga aagactgatt
     4621 gataagattg aacaaatctc tattgcagat ttgattgcgg aagctatcat tcgtatccat
     4681 gaaaaacgtc cattgtcacc cctatttgaa ttagggaaat gataaggtta gcctgaggta
     4741 gtaagcctta ggctttttta tgttttaaaa ggctatttga ttaccaaagc agtgtttgat
     4801 ttaacgccat agataggctt cactgtctta tggtaggtgt tgagctatta tagcaaaaag
     4861 tcatgtgtag gtgctgtgtt taaacagcta gcctatgatt catatagtta tggctagtga
     4921 ctgttgagct tcttattctc agagttgtta cgagccttaa gtacagtgtt agtcatgcaa
     4981 ttttcctgga ttttgggtat aatatagctg tatttaaggt gttttaaagg tctagtaaga
     5041 aaggcattat tactagctga gaagcttggt tatggagata tatgcgtatt cagaggtcac
     5101 ttggtattgt cttgtacaat aaaaactatc gtgaagatga taagctcgta aaaatattta
     5161 cagaagcggc gggcaagcgt atgtttttcg tgaaacatat tggtcgttct aaactagctc
     5221 ctgtggtcca gcctttaacg gctgctgatt ttctattgaa aatcaatgat tcgagccttt
     5281 cttatataga ggattataat caggtggagg cttatcggca catcaatgaa gattttttta
     5341 ggctatccta tgctagttat gtcttggctc tggctgatgc ggctattcca gataatgagc
     5401 ctgatcctca gttgtttgct tttttgaaaa agactcttga tctgatggaa gaagggctag
     5461 attatgacat tttaacgaat atctttgaag tccagatttt ggatcgtttt ggggtgagaa
     5521 tgaattttca tgattgtgtt ttttgtcaca gaaccaatct gccttttgat ttttctcata
     5581 agtattcagg tgtcctttgt ccgcagcatt accatgagga tgagaggcga tatggcttgg
     5641 atcccaatgt gatttatttg cttaatcgtt ttcaaacgct taatattgat gagctaaaga
     5701 ctatttctgt gaatactggt atgaaaaaaa agcttcgtct ttttattgat gccttgtatg
     5761 aggattatgt cggtattcgt ctaaaaagta aggtttttat tgatgatttg gctaagtggg
     5821 gagatattat gaaaaacaag cagggcttgt gagctattca ggtgtggatt tgtcctttta
     5881 tgggaattgt ctggggaata tgctataata gttacgttat tctctaggat atttttcgtt
     5941 aagaaaaata ggattaaagg agcaaaaatg aagaaaattg caatagacgc tatgggtggt
     6001 gattatgccc ctaaagctat tgttgagggt gttaatcagg cgatagaatc cttttcagat
     6061 attgaaattc agctttatgg cgatcaatca aggattgagt cttacctagt taaatcagat
     6121 cgtgtgtcca ttgttcatac agatgaaaaa attaattctg atgatgagcc agcaaaggct
     6181 attcgtcgta agaagaatgc ttctatggtt ttagctgcaa gggcagttaa ggatggtcgg
     6241 gctgatgcag ttctttcggc aggtaataca ggcgccttgt tagctgctgg tttgtttatt
     6301 attggtcgta tcaagggagt ggatcgtcct ggtttgctgt caactctgcc aacggttgat
     6361 ggttcaggct ttgacatgtt agatttgggt gccaatgctg aaaacacagc agagcattta
     6421 caccaatatg ctattttagg ctctttttat gcaaaacatg tgcgtggtat tgccaagcct
     6481 cggattggct tgcttaataa tggtactgag gcaactaagg gtgattctct tcgcaaggag
     6541 gtctataatt ttttagcttc agacagcagc ctacagttta ttgggaatgt tgaggcaaga
     6601 gatttgatgt ctggcgtggc agatgttgtg gtagcagatg gctttacagg aaatgctgtt
     6661 ttgaagtcga ttgaaggcac tgctatgagt attatgggac aattgaaatc agctatagca
     6721 gtaggtggtg ttaaggcaaa gtttggagct cttttattga agagtagcct ttatgactta
     6781 aaggatactt tagattattc cagtgcgggt ggggctgtat tgtttggtct taaagcacct
     6841 cttgtgaaat cacatggttc tagtgatgcc aaggctattt ttcataccat taagcaggtt
     6901 cgtacgatgc tagaaacaga tgtagttggc caattagttg aggagttttc taaggagagt
     6961 gatgtaaatg actgaggaag ttattttaga gaaaatcatc gcattaatca agaagcaaag
     7021 aagtcgtata gactttgaca ttacagaaaa aacagcacta aaggatgatt taggagtaga
     7081 ttcgattgaa ctggtagagt ttgttattaa tatcgaagat gaatttggta ttgatattcc
     7141 tgatgaagat gttgatggca tggtatctat gggagatatg ctaaattatt tggtcaagcg
     7201 tttaaaccaa agctaaatag ttttaaaaga gcaccagctc tttttttgtt tccgaaaaaa
     7261 cgaacattat aagtttattt tatattaaat gtaaataaat gttgaatatt tagtatgttt
     7321 gtggtattgt ttagatatta aatgcaaaga aaggcgaaca aataagtgtc taatcaactc
     7381 atttattcag gtaaggcaaa ggatatctat gaaacagccg atgacgggat tgtcttaatc
     7441 tcctacaagg atcaggtcac tatgctaaat ggagcacata aggaaatgat tgaaggaaaa
     7501 gggagcctta ataatcagat ttctgcctta atctttgata ggctaaatag ggttggcgta
     7561 tcaactcatt ttattaagca attatccgag acagaacagt taaataaaag ggttgcgatt
     7621 attcctttgg aggttgtttt acgaaacgtg gccgctggct cattttcaaa gcgctttggt
     7681 gttaaagaag gtcaggcttt ggacgagcca attattgagc tttattacaa gaatgacgct
     7741 ttagatgatc ctttcattaa tgatgagcat gtcagctttt taaagcttgc gactgatgag
     7801 cagatagcct acatcaaaca agagacgcat cgtattaatg cttatttgaa ggagtggttt
     7861 gctagtgttg ggttgacact ggttgatttt aagctagaat ttggctttga taaggagggg
     7921 atgcttatcc ttgctgatga gttttctccg gataattgcc gcttgtggga taatgcgggc
     7981 cgtcacatgg ataaggacgt ttttcgtcgt cagcttggca gtttgacgca agcctatgag
     8041 actgttttag aaaggctaag agcattggat caataaagac cagcttattt gttgtcagtt
     8101 aagaaaggga gctctttttt gtccgtcatg taagaaaata aatcagttca gactatttga
     8161 gctgctgtct aagaaaggct gtctgctatt ggagaaaaga gtcaggctag ttcttatttt
     8221 gggctggttt ctgattggac ttggtatatt aactatgaat aaacgtattt ttgttgaaaa
     8281 gaaggctgat tttcagatta aggcacaggt cctgttaaag gaattgaaac atcagctgca
     8341 gttaaagaca ctggttgatt tgcgtattgt gcaggtttat gatgtgtttc atttggatca
     8401 ggagctgctt ttaacagcta taaagcatgt tttctctgag caggtcactg atcaggtatt
     8461 gtcagaagaa gctttacaag cagatttaaa aaggtatgcc ttttttgcga ttgaagctct
     8521 gcctggacag tttgatcagc gtgcggcaag ctctcaggaa gccttattgt tgttaggagc
     8581 ctcaactgat gtgactgttt tgacctcaca gctttatttg gtcaatcaag acattgctgc
     8641 tgaagaatta gaagccttaa agcagtactt gttaaatcca gtggattcta ggtttaagga
     8701 catattagcc ggtcttgatg atcaggattt ttcagtagca gataaagtga ttccaacgct
     8761 tgatgttttt aatgattata cagcggaaaa tcttgctcgt tacaggtctg agcagggcct
     8821 agcaatggaa gtggaggatc tgctgtttat tcaggattat ttcaagacaa aggggcgagt
     8881 gccaacagag actgaactaa gggttttgga tacgtattgg tctgatcatt gtcgtcacac
     8941 aacctttgaa acagagctaa aaacgcttga tttttcagct tctcattttg aaaagcagct
     9001 ccaagctacc tatgagacct accttgctat gcgtgatgag ctaggtcgat ctgaaaggcc
     9061 tcaaacgctt atggatatgg ctaccatttt tggacgttat gaaagagcta atggtcgttt
     9121 agaggatttg gaggtttcag atgaaatcaa tgcttactca gtggaaattg aggtagatgt
     9181 tgatggtgtc aaggagcctt ggctgctcat gtttaaaaat gaaacacata atcacccaac
     9241 ggaaattgaa ccctttgggg gtgctgcaac ctgtattggt ggagctattc gtgatcctct
     9301 gtcaggccgt tcctatgttt atcaagccat gcggctttct ggtgcagggg acattacaag
     9361 cccgctgtca gagactcgta agggcaaatt accacagcag gttatttcga ggcaagcagc
     9421 acatggttac tcgtcatatg gcaatcaaat tgggctagcg actacttatg ttcgtgagta
     9481 ttttcaccca ggctttgttg ccaaacgtat ggagcttggt gcggtagttg gtgctgcacc
     9541 caaggaaaat gtggttcgtg aaaagccaag gacaggtgac gtggtggttt tgcttggtgg
     9601 gaaaacagga cgtgatggta ttggtggtgc gacaggatca tctaaggttc agacagttga
     9661 gtctgtagaa acagctggtg cagaggtcca aaaaggaaat gccattgagg agcgtaaaat
     9721 ccaacgtctt tttcgtcgtg gcgatgtgac acgcctcatc aagaagtcaa atgattttgg
     9781 tgctggtggt gtttgtgtag ccattggcga gcttgctgct ggtcttaaca ttaacttaga
     9841 taagattcct ttaaaatatg ctgggctaaa tggaacagaa attgccattt cagaatccca
     9901 agagcgtatg gctgtcgtga tttgtccaaa ggatttagag gcctttatga gcgcctgcca
     9961 taaggaaaat atccatgctg ctgttgtggc agctgtgaca gaaaaaccga atcttgttat
    10021 gacctggaat gggcagacga ttgttgatat tgaacgctca tttttagaga caaatggtgt
    10081 gcgcgtgtct gttgctgcta aggttgttga cagtggtgcg ccaataccag aagctcgtca
    10141 aactactgct gagacacttg aagcagatac cattgctgtc ttatcagacc tgaaccatgc
    10201 tagtcaaaag ggtttgcaaa ccctgtttga tagctcagtg ggtcgctcta cagtaataca
    10261 tccgcttggt gggcgctatc aaatgacacc tgttgaaggc tctgttcaga aattaccagt
    10321 tcaacatgga gtgacaaaga cagtctctgt tatcgctcaa ggctatcacc cttatatagc
    10381 cgaatggtca ccttatcatg gtgctgctta tgctgtaatt gaggcaactg ctcgtctggt
    10441 cgcaacgggt agccattggc ataaggcacg cttttcatat caggaatatt tccaaagaat
    10501 ggataagcag gcagagcgct ttggtcaacc ggtggcagcc ttgcttggag caattgaagc
    10561 acaggtgcag cttggcttgc cttctattgg aggtaaggat tcaatgtctg gtagctttga
    10621 ggaattgaca gtgccgccga ccttggttgc ctttggtgtg acgactgctc atgtagatca
    10681 tatcctttca ccagaattta aagctgctgg cgagaatatt tactatattc caggacaggc
    10741 tatttcggaa gtgattgatt ttgagttgat aaaatctaat tttatgactt ttgaggctat
    10801 tcagaaaaag cataatatta gctcagcttc ggctgttaaa tatggtggtg ttgttgaagc
    10861 actggctctt gctgcctttg gtaatcggtt aggggcttgt gtgacattac cagagcttga
    10921 caggagctta acagctcagc ttggtggctt tatctttaca tcaaaagagg aaatcacagg
    10981 tgttatcaag cttggtcaaa ctaccagtga ctttacattg gttgtcaatg atgtcaagct
    11041 atctggagct cgtctcttaa aggcttttga agggagcctg gagcaggttt acccgacggt
    11101 atttcagcag gcaggtgaat tgaagcctgt tcctgtagtg acaacagcac ttgctgctca
    11161 gtttaaggaa aaaatagctc agccagttgt ctatattcca gtttttccag gaactaactc
    11221 agaatatgat tcggctaagg cctttgaaag agagggtgca agggtgaact tggtgccttt
    11281 tgttaccttg aatgaggcag ctattgacgc ttcagttgac acgatggttg accatattca
    11341 tcaagctcat attatcttcc ttgcaggtgg tttttcagcg gcagatgagc cagatggttc
    11401 agctaaattt attgttaata tcctgctgaa tgagaaggtt cgaatggcga ttgatgcctt
    11461 tattgaaaag ggtggtctga ttatcggtat ttgtaatggc tttcaagctc tggtcaaatc
    11521 agggctgctg ccatatggac gttttgaggc ggtacatgag gctagtccaa ctctgtttta
    11581 taatgatgcc aatcagcatg tggctaaaat ggtagaaacg cgtattgcca ataccaattc
    11641 tccttggctg gcaggtgtca gggtggggga tattcatgct gttgcagtgt cacatggaga
    11701 gggcaagctt gtggtaacag aaagagaatt agcagagctt tgtaaaaatg gtcagatttt
    11761 tagccagtat gttgaccttg atggtaatcc aagcatggat agcaggtata atccaaatgg
    11821 ctctgtcaac gctattgaag gtcttaccag caaaaatggt cagattatcg gtaagatggg
    11881 acattcagag cgctttgaag agggactttt ccaaaatatt ccgggtaata aggatcaatg
    11941 gttattccga agtgcggtgc attattttag aggagaccat gtgggtattg actgaactgg
    12001 gatatagcct tgtaatagct aagatagctg ctattattgc tcagcctagc tgttagttct
    12061 agcttagtta atgacacaat cataattaaa agggcattag cccagaggta aagatgacat
    12121 atgacgtaaa atctcttaat gaggaatgtg gtgtttttgg gatttgggga cacccacatg
    12181 ccgctcaagt gacttatttt gggcttcata gcctacagca ccgcggccaa gagggagcag
    12241 gtattatttc aaatgataat ggggagcttc atcagcatcg tgatgtaggt ctcttgtcag
    12301 aggtgtttaa ggattcatct gatctggaca agctaaaggg acatgctgcc attggtcatg
    12361 tgcggtatgc gactgctggg acggcttcca ttaataatat tcagcccttt ttatatcgtt
    12421 ttacagacgc tcaatttggc ttgtgccaca atggtaattt gaccaatgct atgtcattga
    12481 aaaaagcgtt agagagtgag ggagctattt ttaatgcctc ttctgataca gaaattctaa
    12541 tgcatttgat tcgtcgtagt catcacccag aatttttagg aaaggtaaaa gaggcactca
    12601 acactgttaa agggggcttt gcttacctgc tgatgacaga gaaccagctg atagcagcgc
    12661 ttgatccaaa cggctttagg ccgttgtcta taggccgtat gaaaaatggg gcttgggtcg
    12721 tctcaagtga gacctgtgcc tttgaagtgg ttggtgctga gtgggttcgc gatgtgatgc
    12781 caggtgaggt cattatcatt gatgatcagg ggatcactta tgactgctat acgactacta
    12841 cgcagctggc tatctgctct atggaatata tttactttgc gcgtcctgat tcaaccattg
    12901 ctggagtcaa tgttcacacc gctcgcaagc gaatgggaaa gagactggct caggaatttc
    12961 agcatgaggc tgatattgtg gttggtgtgc caaattcctc attatcagca gcgatgggct
    13021 ttgcagaagc atcaggcctg ccaaatgaaa tgggattggt caagaatcaa tatacccaac
    13081 gaacctttat ccaaccaact caggagcttc gtgagcaggg agttcgaatg aaactttcag
    13141 ctgtttcagg tgttgtcaag ggcaaaaggg ttgtgatggt agatgattct attgtcagag
    13201 ggacaacctc acgacgcatt gttaatttgc tgcgtgaagc aggagctaca gaggttcatg
    13261 tagcaattgg tagccctgag ctcaaatacc cttgctttta tgggattgat attcagacaa
    13321 gacgggagct gatttcagct aatcatactg ctgctgaggt ctgtgatatt atcggtgctg
    13381 atagcctgac ttatttgtca cttgatgggc ttatcgaggc tattggactt gatacaaaag
    13441 caccaaatgg tgggctttgt gtggcttatt ttgacggtca gtatccaacg ccgctttatg
    13501 attatgagga ggcttatctc aagagcttag aagaaaaggt aagctttcac attgatcagg
    13561 tgacgaagta gcgctttatg gctaacatag aataaatgat ctaggcagct aaaataagga
    13621 ggagaaaatg tctaaaaatg cttatgctca atcaggtgtc gatgttgaag caggctatga
    13681 gcttgttgag cgaataaaaa agcatgccga gcgtagcaaa cgattgggtg ttatgggtgg
    13741 tctaggaggc tttggtggtc tgtttgacct gtcaaagact ggtgttaagg agcctgtttt
    13801 ggtttcaggg acagatggcg tcggaacaaa gctaatgctt gcaatccagt acgataagca
    13861 tgacacgatt gggcaggatt gtgtggcaat gtgtgtcaat gatattattg cagcaggtgc
    13921 cgaacccctg tattttcttg attaccttgc agcaggaaaa aatgagcctg ccaaattaga
    13981 gcaggtgatt gcaggtattg ctgagggctg tgttcaagca ggtgctgctc ttatcggtgg
    14041 agaaactgct gagatgcctg gtatgtatgg tcaagatgac tatgatcttg ccggttttgc
    14101 ggttggtatt gctgagaaat ctcagctgat tgatggttca agagtagctg agggagatca
    14161 tctcctaggt ttggcatcaa gtggagttca ttcaaatggt tattccttgg ttcgtcgtat
    14221 ttttgccggt tatactggtg aggagctgct tccagagctt gatggaaaaa agcttaagga
    14281 ggtacttctt gagccaactc gtatttatgt caaggctgtg ttaccactca ttaaaagcgg
    14341 cttagtggca ggaatcgctc atattacggg tggcggcttt attgaaaacc tacctcgtat
    14401 gttttccaaa gaactagccg ctgaaattga agaagccagc ttacctgtgc tgcccatttt
    14461 taaagtcctt gagacatatg gtaagatcaa tcatgaagaa atgtttgaga tttttaatat
    14521 gggtattggc atggtgcttg ctgtcaagcc tgagcacgtt gagcaggtga aggcctgtct
    14581 tgatgagcct gtgtatgaca ttggtcgcgt tgtgaccaga acagttgcta gtgtggtgat
    14641 gaagccatga caagaattgc cgtttttgct tctggtaatg gctccaattt tcaaacgatt
    14701 gcagaacagt ttccggttgc ctttgttttt tctgatcatt gcgatgctca tgttttaagt
    14761 agagcctgtg ctttgggtgt tctgtcctac agctttgaac taaaggactt tgagaataag
    14821 caagcctatg agcagactct tgtggcattg ctgcagcggc atcagattga tctcatcgtc
    14881 cttgccggct atatgaaaat tgtgagtaca accttacttg atgcttacga aggaaaaatc
    14941 atcaacattc acccagctta tttgccagaa tttccaggag cacatggtat tttagatgct
    15001 tggcaagcag gtgttagtca gtcaggagtg actgttcatt gggttgatag tggtattgat
    15061 acaggaaaaa tcatcaaaca ggtacgagta ccacgtttga gtgatgatac tcttgaaagc
    15121 tttgaagcca gaattcatga agcagaatac caattgtatc cagaggtact ggatagtctt
    15181 ggagtagagc ggcttaaccg ctgattgtgt aagattaata actattttcc ctattgtggc
    15241 atttcgttta tcatagcagc tgcgctaatg gtggctaaca aaggctagaa gacttgtttg
    15301 atgatggcac tgctattgag gaaaatagac ttttctaagg agaacttaaa atgactaaac
    15361 gcgccttaat tagcgtatca gataaaagag ggattgtgga ccttgctagg gagcttaagc
    15421 atcttggctg ggatattata tcaacaggag gaacaaggct tgctcttgaa gaggctggtg
    15481 tagttactgt tgctattgac gatgtgacag gctttcctga aatgatggac ggacgggtaa
    15541 aaacgctgca ccctctcatt catggtggct tacttgctcg tcgtgacatt gagcaccact
    15601 tacaggcagc aaagcaaaac aggattgaat taatagacct tgttgttgtt aacctttatc
    15661 ccttcaaaga aaccatttgc cgtccagatg tcacttatga tgtcgctgtt gatatggttg
    15721 atattggtgg tccttcactg ctgcgttcag cggctaaaaa tcatgctagt gttacggtag
    15781 tggttgatcc gacagattat ccgctcgttt taggagagtt ggctagcact ggcagtacaa
    15841 gttaccaaac ccgtcaaagc ttagcagcta aagcttttcg ccatactgca gcctatgatg
    15901 cagtgattgc agattatttt acaagacaag caggtgagac aaagcctgaa aagctcacgc
    15961 ttacctatga tttgaagcaa agcatgcgtt acggtgaaaa tcctcaacag gctgcagatt
    16021 tttaccaaag agcgctccca acaacctatt caattgcttc agccaagcag ctaaatggaa
    16081 aagagctatc attcaacaat attcgtgatg cagatgctgc gattcgtatt attcgtgatt
    16141 ttaaggagcg tccaaccgtt gtagcactca agcatatgaa tccatgtggt attggtcagg
    16201 cagatgatat tgagacagct tgggattttg cttatgcagc tgatccggtg tctatctttg
    16261 gtggtattgt tgtcctaaat cgtgaggtgg atctagcgac agcggagaag cttcatgcta
    16321 tttttcttga attgatcatt gcaccaggct attccaaaga agcgctagct gttctcaccc
    16381 ataaaaagaa gcacttgcga attcttgaat tgccatttgc tgctcaggag gctagtgaaa
    16441 tagaagcaga atatacagga gttcttggtg gtctactagt gcaaaatcaa gatgttgtca
    16501 cagagtctcc agcggattgg atagtggtga caaagcgtca gccaaatgaa caggaaatgg
    16561 ctgctctagc atttgcttgg aaaaccatca aatatgtcaa gtctaatgcg attgtcattg
    16621 ctaatgatca tatgactttg ggcgttggtc cagggcaaac aaaccgaata gcctctattc
    16681 gtattgctat tgcgcaagca acggggcagc ttgagggagc agttcttgct agcgatgcct
    16741 tcttcccatt tgcagacagc attgaagaaa ttgctgccgc tggtatcaag gctattatcc
    16801 agcctggagg ctctattcgt gattcagaat ctattgcagc tgccaatcag catggtataa
    16861 ccatgatttt cacaggtgtg aggcatttta gacattaata aagtaaaaag agactggagc
    16921 caaaagagtt gcactttaga aattcttggt taatatactt tattacctag ttggattcat
    16981 taaaaagcga acaagtctag ttttcataat ctcagaaaac tagacttgtt tgcttgtttt
    17041 atttggtggt catactattg tttcagcctc tttttactat gactaataca agaatttatg
    17101 aaggaacaag gctttatttt ttgttgtggt aacagtgacc agatccgtta tcaatcagta
    17161 tttgagtatt ttgagctcta gatgcatcac ttagatagga tattgcaaag gatacagctg
    17221 ctgcatgtat taggaaagca ttatcataaa aggctttttc gttagcctaa aggttttaga
    17281 ccttctttgc cttatctatt gttaaccatg ttccacgtga acccatttgc acgtaaatcc
    17341 ccttgctagg ctgatcaacc tttagaacct tataggttcc tgaaacgaca aaataatcac
    17401 ccacctgcaa aatctgattt ccagcaatac gtcctttatg gtccgtttcg tggagtggag
    17461 ctgagtctat ccagtttaag gaggttggct ctccaccggc taattcactg cttgcaatca
    17521 tgttctgagc gacctgatcg acccgaaaaa caccaggaaa ggctacagta tctccaacct
    17581 tgataggagt ggtcgccaca ggctttggtt tatctataga ggcttgacta tgttgctgag
    17641 gctgaaccgg caatttgtga attggaatgt agcgatgatt tcctgaatga ccgatatagc
    17701 tgagccattc atagccatca gcgacaaggg tttgatcata gtgcactaac tgtccagtat
    17761 gatagtaagc taaatcagga cttgctaatg tagcttcagc ctttatagga ctttggcttg
    17821 aaaaataata ggtaccactt ttagctagac gagttgatcc tgcttgagaa gcatgtaaca
    17881 tttgtgtgtg gctggtagag ttgtgatcca gatccttgaa gtgaatgtaa ccacttacct
    17941 gatgcttatg aatctgtcgt ttatgatact tttcaggtcc ctgtccggca ttatagttgt
    18001 attcctcaat aataacagtg tcaccattga cctctgctac ccaggcgacg tgtccatata
    18061 gggcatgtga ctggttaaag cccttatccc accaagcaac agcaccaact ctaggtgtat
    18121 gatcaacatg atagccttgg tgtttagcta tacgtcccca gctttcaaca ttaccatagc
    18181 ctctaggcag gctgaatcca tttgaggaat gcagtcggaa tgctacaaaa gaagtgcatt
    18241 gacgtaagta catgttccaa ggatcagctc cgaagccctg tttccactta cttggatagt
    18301 tatcccctaa aacagcagcg tgtacgatac ctgactgacc ttgtgaaatc gttgttgtgg
    18361 cagaggatat tgcaccatta ccacctaaaa ggattgctcc tgaagctaac aattgataga
    18421 cttttttcat taattacctc ctgtaactta ctattcgcaa gaaagaggac aaaaatgtcc
    18481 ttgatttaaa aaaatgtaag gaaaaatatt ttagcctcaa aatactgttg gtgctcccta
    18541 gcttccaaga gccaataggc aagcccatct ccagcttgcc tgctccctgt agctaaaagc
    18601 aatttatagt aacactagca cctcatctga agaggcaggc tgtggtaatt aatgccaata
    18661 atctgtaaaa agagacagca ggtatggtta tatgagctat gatggttata ttctataaag
    18721 cttatttttt agcttcgggc tttctttggt gattagttat ttatataaac gaacaattat
    18781 gctaaaatat gtttataaaa ttcgtgttat gaggtgtgtg atgaagcttt tagttatcgg
    18841 ttcaggtggt cgtgaacatg cgattgctaa gaaattgtta gagtcaaaag gcgttgaaca
    18901 ggtttttgtg gcacctggca atgatggcat gacccttgat ggcatagaac gggtagatat
    18961 tgatatttcc gaacattctg ctttgattgc ttttgcaaag accaatcata tagcctggac
    19021 ctttgtggga ccagatgacg cattagcggc tggtatcgtt gatgagttta accagtctgg
    19081 cttgaaagcc tttgggccct ctcgtttagc agcggagctg gagtggtcaa aggactttgc
    19141 taagcaaatc atggtcaaat acggtattcc aacagcagcc tatggcacat tttctgattt
    19201 tgcaaaagcc aaggcctaca tcgaggaaaa gggcgcgcca attgtggtta aagcagatgg
    19261 tttggcgcta ggaaagggtg ttgtcgtagc agagactgta gagcaggcag ttgaggcggc
    19321 gcgtgacatg ctcttggata ataaatttgg tgattcaggt gcgcgcgtgg tgattgagga
    19381 atttttagct ggtgaagagt tctctctctt tgcctttgtg aatggcgatc agttttacct
    19441 catgccgaca gcgcaggacc acaagcgggc tcttgatggt gacaaggggc caaatacagg
    19501 tggtatgggg gcttatgcac cagtgcctca tctttctcaa agtgtggtgg atacagcagt
    19561 tgagaccatt gtcaagcctg ttctaaaagg gatgatgaca gaggggcgtc cctatcttgg
    19621 aatcctttac tgtggcttga ttttgacaga agatggacca aaagtgattg aattcaatgc
    19681 tcgctttggt gatcctgaga ctcaggttat ccttcctcgc ctgacctctg attttgcaca
    19741 gaacattacc gatatattag agggcaacac agctaatatc acatggtcag acgagggagt
    19801 gacgctcggc gttgtccttg cttcaaacgg ttatccgctt gcttacaaga aaggtgtgct
    19861 tctgccagca aagaccactg gcgacatcat tacctactac gcaggggtta agcttgcgga
    19921 aaatggcaaa gcactgctgt caaatggtgg acgtgtctat atgctggtca ccacagcagt
    19981 taccgtccca gctgcgcaag aaaaaatcta taccgaactt gctcagcaaa ataccgaagg
    20041 attattctac cgaaacgata ttggaagaaa agcagtaaaa taaattagcg ctagctcaag
    20101 ctaccgaagg tcgctatgat gacaatgact tattatcggt gagcaaaagc gagcctaaca
    20161 cgatactttt cgccgtagcg caaagagtga caaggtcact cgggggaact tgaaagacct
    20221 tgggctttca agttagtcat gagacaccta tggtggctgt tgacgccccc ccccacttaa
    20281 gaaaagtatc aaaaaccttt aaggagaaag tatgaaacca attatctcta tcatcatggg
    20341 ctccaaatct gactggacca ccatgcaaaa aaccgccgaa atcctcgacc agtttggcct
    20401 tgcctacgaa aaaaaagtgg tctctgccca ccgcacgccg gatctcatgt tcacatacgc
    20461 tgagaaagca cgcgaacgtg gcattaaaat catcatcgct ggtgctggcg gagcagccca
    20521 tctccctgga atggtcgctg caaagacgac acttcctgtt atcggcgtac ctgtcaaatc
    20581 gcgtgctctt agtggtcttg attcgctgta ttcaattgtg cagatgccag gtggtgtgcc
    20641 tgtggcaact atggccattg gagaggcagg agcaaccaat gcagcactga ctgctcttcg
    20701 gatcctttca attgaggatg aaacaatcgc agagcagctc agccatttcc acaaagagca
    20761 aggacggatc gcagaggagt caacccatga actcaactaa aacaattgga attatcggag
    20821 gtggtcagct gggacagatg atggcgattt ctgccattta tatggggcat aaggtcatta
    20881 cactggatcc agcagcggat tgcccagcct cgcgcgtgag tgaggttatc gtggcgcctt
    20941 atagtgatgt ggaggcgctg cgtcaattga ccgagcgctg tgatattttg acctatgaat
    21001 ttgaaaatgt ggacgctgac gcccttgata cagtggtaaa ggaggagcag ctgcctcaag
    21061 gaacagagtt acttcggatc tcgcagaatc gtatttttga aaaagatttt ttagccaata
    21121 aagcaagcgc ggcagtggca ccctacaagg ttgtaacctc tagcctcgac ttggaaaacc
    21181 ttgacttttc gaaaaaatac gtcctcaaga cagcgacagg tggctatgat ggacacggtc
    21241 aagtcgttat tcgctccgaa gcagaccttg aagaggctaa taagttggct aacactgccg
    21301 agtgcgtctt ggaagaattt gtcagctttg accgagagat ttccgttatt gtatctggca
    21361 atggcacaga tgtcactgtc tttcctgttc aggaaaatat ccatcggaac aatatcctgt
    21421 caaaaaccat tgtcccagct cgcatttcag aagcagttag cgctaaatcg caggctatgg
    21481 cggtgaaaat agcagagcag cttaacctat ctggcaccct ctgtgtagaa atgtttgtgg
    21541 caggcgacga gattttggtc aatgaaatcg ccccacgtcc ccacaactca ggacattact
    21601 ccatcgaagc ctgtgatttc tcccagtttg acacccacat tttaggtgta ttaggccagc
    21661 cattaccagc tgtcaaactc catgccccag ccattatgct caacgtcctc ggccagcaca
    21721 tggaacaagc ccaacgctac gccacagaaa accctagcgc ccacctccac ctctatggta
    21781 aaatagaagc caagcacaac cgcaaaatgg gacacgtgac ggtgtttaac agtcaatcag
    21841 atgaggttga agaattttag gaggaattaa tcctatgata aaaatcattg ttcacgcttt
    21901 tattgaaaat ggtgaaacag gtgttgttga agttgtcttt gcttcggaaa accaagaatc
    21961 catttctgaa aaaatgacgg agctacaaaa gcaatatcca aacgattacc ttgctatcta
    22021 tgatttacca ctagatacag acctatcgca attggcccac tatccgtcaa tagcgatagg
    22081 caaaggggag tttgagtagt taaggaagat tagtatttcg gattgagtgt tattgggaca
    22141 atttatggct atgcctttca aaagattggt catgatgttg agcatgttgt gagaattgag
    22201 aatcgtaatc agatttcaga agttggtaaa tgacttaatg gataattcta gatactgatc
    22261 tcgagcaatc ataagagaaa tgttgaaatt gtagcttctg gaggtgtaga actcaaaaat
    22321 tatcgtggtg agatatttcc atataaaact tctaagcgta tttcgtctag attgataaca
    22381 tatagatagg tttgtacata atgaacttac tagatgcatc atgacaaagc agatctttta
    22441 tatacatgca aagaggttta caatattggt atagtcaact attgatgccc taacttttaa
    22501 tcacaatata gaaattattg cgaatagact ttaaaagcat tactattaac tatgtagaaa
    22561 ggaaatgagc gctagaattt tcaaactgaa cctgagcgga aagctcggaa tttagataaa
    22621 tttcctcgga cgtaaatgtc cgtctttagc tttctaaaat tcagttgctt tctggctgtt
    22681 cttggtatct taattatgct aaaccgttat tcacgccctg agatggcgaa gatttggagt
    22741 gaagagaaca agtaccgtgc ttggttggag gtggaaatcc tcgctgatga ggcatgggct
    22801 gagttgggtg agattcccaa ggaagatgtg gcgaagattc gcgccaatgc gagttttgac
    22861 atcaatcgta ttttggagat tgaagaagag acccgtcacg atgtggtggc ctttactcgt
    22921 gcggtgtctg aaacgctcgg tgaggagcgc aagtgggtcc actatggctt gacatcgact
    22981 gacgtggtgg atacggccta tggctatctc tacaagcagg ctaatgacat tatccgtcgt
    23041 gaccttgaaa actttaccaa cattgtggct gagaaggcta aggagcacaa aatgactatc
    23101 atgatggggc gtactcatgg tgtgcacgcg gagccaacga ccttcggtct caaattggcg
    23161 acctggtaca gtgaaatgaa gcgtaatcaa gagcgttttg agcatgcggc tgctggtgtt
    23221 gaggccggta aaatctcagg tgctgttgga aactttgcca atatcccacc atttgttgag
    23281 gagtatgtct gtggcaagct aggcattcgc ccgcaggaaa tctcaactca ggtcttgcca
    23341 cgagaccttc atgccgagta cttcgcagtg cttgctagta tcgcgacatc aattgaacgc
    23401 atggcaactg aaattcgagg cctgcaaaaa tctgagcaac gtgaggtaga agagttcttt
    23461 gccaaaggac aaaagggaag ctctgccatg cctcataagc gtaacccgat cggctctgaa
    23521 aacatgacgg ggcttgcgcg tgtcattcgt gggcacatgg tgacagccta tgagaacgtg
    23581 gcgctttggc atgagcgtga tatttcgcac tcgtcagcag agcggattat cacaccagac
    23641 acgactatcc tcatcaacta catgctcaac cgttttggca atatcgtcaa aaatttgaca
    23701 gtctttccag aaaacatgac tcgtaacatg aactctacct ttggcttgat ttacagccaa
    23761 cgtgtgatgc ttaagctgat cgaaaaaggc atgacgcgtg aggaggcgta tgacttggta
    23821 cagccaaaga cagcctattc atgggacaac caagtggact tcaagccgat ccttgaggca
    23881 gacgaaaata tcactgcaaa attaaggcaa gatgagcttg atgagctctt caatccagct
    23941 tattatacca agcgtgtcga tgctattttc gaccgattag gattatagga agaaaacagc
    24001 gcgtcttttt agactgtagc taagcccaga tttgtttaaa aagtcttgaa aatgaattcc
    24061 tcggagctaa ttctcaaaat gaagaatagt atttcaagag aggctgtcac tagctatatc
    24121 gcttaagaaa atgctctaaa atagacattt tttcaatctg agaaggcaat aggccttctt
    24181 tttttctaaa aatacagaaa tgttattata gaatggagtc aaaaaattaa taattaatta
    24241 aattatgtga tataatgaaa gaaatagtgt cttgaagagg gaaacatgtt agacaatttt
    24301 ggtgaaaagg tgagagacct tcggtatcag aaaaaaatta ccagagagga tttatgtgga
    24361 gatgagtcag aattatccat tcgtcaattg gcacgaatag aactgggcca atcgattccc
    24421 agcctatcaa aggtggtttt tattgctaag gctttggacg ttagtgtcgg ctttttgaca
    24481 gacggagagg atttggagct accgaagcgc tataggagct taaatatttg attttaagaa
    24541 caccgaccta tatggacgat gacaaattaa agctgcgaga agagcaattt gacgaaattt
    24601 ttgaagatta ttatgaccag ttgccagagg aagaaaagct tgtggtggat tgcttgcagt
    24661 ccataatgga tacgttatta accgagaata tcaattttgg agttgggtta ttacaggaat
    24721 actttgaaca aacaaaaagt aagactcaat ttagagagaa tgatctcatt cttattgagc
    24781 tgtatttagc gtacctcgac attgcaggaa tgaatggaga gtattcagat aaaggattct
    24841 atgattcttt gttagacatt ttgttaaatc agtttgaaca ttttgaatta gaggaattat
    24901 ttattgtcaa taaaatagct ataggaattt cctcgttgag catcaaaaac aataagccgg
    24961 agattcttga gaaggttatt gtacttagtc aaaaaattat cctcaagact caggatttta
    25021 atagaatgcc tatcttaaat ttgatagagt ggaaatatgc tctaatgaag aaaaaagaca
    25081 tagaaatggc caaaaaatgc tatgctaagg catgcctgtt tgctcaatta acaggagatc
    25141 agtatttgga aaagaaattg agagaagaat ggggtaaaga tataaaacga tatcaatagg
    25201 acaaaaatgt catttttatc aaaaatggaa taatatataa tctttatata acaaataatt
    25261 gattaaagga gttccattta tatgtttaaa aaataccaat actatctgtt tttagctgct
    25321 ttatttctac ttcattctgc ccaattactt agtgatattg actggtggcg tgttggttaa
    25381 agctaaatca tctatttatg ctataatagc tctatgacaa gaattttaga taatgatctg
    25441 ataggcgatg aaggatctgt tgagaggaca ctacgtccac agtatttacg tgagtatatt
    25501 ggtcaggata gggttaaaga ccagctgatg atttttattg aggcagccaa gaggcgtgag
    25561 gaatccttgg atcatgtcct gttatttggt tccccaggct tgggtaaaac aacgatggcc
    25621 tttgtcattg ccaatgaatt gggagttcat ctcaagcaga cctctggccc agccattgaa
    25681 aaagctggtg atttggtggc aattttgaat gatttagagc caggagatgt cctctttatt
    25741 gatgaaattc atcgtatgcc gatggctgtt gaggaaatct tgtacagtgc catggaggat
    25801 ttttacattg atatcatgat tggcgctgga gacactagcc ggagtgtgca tttggagctg
    25861 cctcccttta cattaattgg agcaacgact cgtgcaggca tgctgtcaaa tcctttgagg
    25921 gctcgttttg ggattactgg gcatatggaa tattatcaga cagctgattt aacagagatt
    25981 gtggagcgta cagctgatat ttttgacatg acaatcaagc atgaggccgc ttatgaactg
    26041 gcacgcagga gtcgtggaac ccctcgtatt gctaatcggc tgttaaaaag ggtgcgtgat
    26101 tatgctcaaa ttatgggtga tggaatgatt acgactcaaa tcacagataa ggctctaacg
    26161 atgttagatg tggatcaaga aggtttagat tatgtggacc aaaagattct tcgtaccatg
    26221 attgaggtgt accaaggagg gccggttggt cttgggactc tatctgtcaa tatagcagag
    26281 gagcgagata cagtagaaga catgtacgag ccttatttaa ttcaaaaggg ttttatcatg
    26341 cgtaccagaa caggccgagt tgtcaccgaa aaagcctatc agcacttagg ctatccctat
    26401 gaaaaaacca ttaagacata aatagctatg taagacttga ttcctttgtt tttaccggtg
    26461 tcaagtcttt tgtattgtca atagcttact gagtaaaaaa gtaaaacgat gtgaggtgag
    26521 gggtgattgg tcagggaagc agaggtgctt tcactagaca aagcattaaa aaacattttt
    26581 agatcaattg aacgaaaatt ataagagcga tttctccttt tggccctata attttgctat
    26641 aataggtaaa aggagttttt catgaaaaaa gtatgctttg tttgtcttgg aaatatttgt
    26701 cgtagtccta tggccgaatt tgtcatgaaa agtatggcca gtcctgatga gctacaggtg
    26761 gagagtcgtg caacctctgg ctgggagcat ggcaatccaa ttcatcatgg gacacaatcg
    26821 ctattacagc aatatcagat tagctatgat accaagaaaa cctctcagca aatcaccagc
    26881 tttgactttg aagcctttga ctatattatc ggaatggata gccataatat cagagatttg
    26941 aagcaaatgt ccaagcatca gtgggattcc aagatccatc tttttattga aggaggcgtt
    27001 ccggatcctt ggtatacagg agattttgaa gaaacctacc gcttggttaa agcgggctgt
    27061 cagcattggt tgagtcaaat cagcgctgaa catgaatcac atgtggaaat agatgagtaa
    27121 tagtaatgaa agcaataata aataacattc aaaaatggca gatcactcgg acaaagctag
    27181 agattatttc agtccttgtg attattgtct gtggattgtc ggtttttacc ttgaccatat
    27241 cctcaaaagc aagcttgacc tatgacaatg ggcaaatcaa gtacaccggc tatgtcctta
    27301 atcatagaat gaatggtaaa gggaaattgg tttaccctaa tggcgatacc tatgttgggg
    27361 attttaataa aggtgtcttt gatggagaag gaacgtttac agctagtaca gggtggtctt
    27421 acagcggaca atttaaaaaa ggtcaggctg atggcaaggg tactttgaag gcgaaggatt
    27481 caaaggttta caaaggaacc tttaagcagg ggatatttca aaaatgagga taaaatggtt
    27541 ttcgtttatt agggtaacag gtcttttgct ggtgttgctc tatcactttt ttaagcatac
    27601 tttttcagga ggctttgttg gcgttgacat cttctttact ttttcaggct atttgattac
    27661 agccttgttg attgatgaat atgtctcaaa acaaaccatt gatgtggttg ctttttttag
    27721 aaggcgtttt tatcgtattg taccgccgct tgtcttgtta attctcttga caattccctt
    27781 tactttttta gtcaaaagtg acttcattgc tggtatcggt cagcaaatag cagctgccct
    27841 agggtttaca acaaatagtt atgagctact gacaggcagt agctatgaaa gtcaattcat
    27901 tccgcatctg tttgtgcata cctggagctt ggccattgag gtgcattttt atttgctttg
    27961 ggggctgttg gtttggttat tagctaaaaa aggctacagt cagaagaaat ttagaggcat
    28021 tctgttttta atttcttccg cagtgttcac gcttagctac ttcagcatgt ttatcagagc
    28081 cttctttgta tcagattttt cttctgttta cttttcaacg ctttcacaca gctttccttt
    28141 ctttttagga gcgatgtttg caaccatgac gggaattaag gacacgactg ttcgctttca
    28201 aaagaatgtt aagctgtggc caaggctaca tgttattgga gtgatggctg gcgcttttgc
    28261 tctgttgttg tttctaacgc ttgtgttaga ttttaaccat atctttacct atcttttcgg
    28321 ttttgtctta gccagtcttt ttgcttcggt aatgatttat gctgcgcgtg ttttgagcga
    28381 tcaaacacca acctggcagg aaccactgct tgtgacctat cttgcggata ttagctatgg
    28441 gatttattta ttccattggc cattttacat tatttttaca cagctgatgt ctaactggct
    28501 ggcagtgatc ttaacggttt tcttttcagt agtgttttca acgctttctt attacattat
    28561 tgagcctttg attcaaggca agacaccaca gctttttggt ttagcaattg attgtaatcc
    28621 ctataagaaa tggttatcag ggcttgcttt aggactcttt ttgttgatgg ttggtacctg
    28681 tttgacagca ccaagggtcg gtaattttga gacccagctt ttagtagatt ccttgcagca
    28741 atctcaaagt aatctcaata agacacatac tttggcagca ggagatgcgc atgctcttag
    28801 tgatgttagc attattggtg actcagttgc cttgaggtct agtgacgctt tttcaaaatt
    28861 aatgccgact gctcaactag acgctgctgt cagccgcaat ttcagtgaag cctttgagct
    28921 ttttgaaaat catatccaat ccaagagctt atcaaaaaca acggttttag ctgttggtgt
    28981 taattctctt tataattatg cgcaggatat tcaaggcttt atttatgcac taccaaaggg
    29041 gcatcgcttg gtgattgtgt cgccctatga tgctaagaat gcagcacagg tagcagaggc
    29101 tagagagcat ttgttgcagc tagctaaaaa atatagctat gtaacagttg ctgactggta
    29161 caaggcggca gtcgaaaatc ccaatatctg gtatggtagt gatggggtcc actacaataa
    29221 cgacgccaaa ttaaaaggtg ctgacttata tgtctcaacg attcaggcgg ctgttgagcg
    29281 agcagcaaaa aaagatgcta aatagtggtg ctaacaacaa tttgttaaga attaataacg
    29341 aaggcttggt cttacaaaca gatcaagcct tttcatgatg tgatttttag atcgtcttgc
    29401 gccctttagc gcgagataaa gctccacctg ttagacagtg tcattattgg ctgttattgc
    29461 tgacggtgac gtgcttttaa aaacggatca ttaaataatt tagcctgatc taaaaaagaa
    29521 agcgctttcg gaacaaagtg aatgcgtcag ccattatttc agaaaaaatc caccaagcca
    29581 aaccccttgt tatcaaagag tttcggaaat tgattgaaaa aacatcacaa ttttattgtg
    29641 aaatgattta caaaatgcca aaaaatgata taatattttt gtaaacaaaa ttgtgaaact
    29701 tttaacaagg taaaggagtc tcaaatgact gaaaaaaata gtactgttga aacaacatct
    29761 gttgccgcaa caattgacgc tcttgttcaa aaaggtttag tagcgcttga taaaatgcgt
    29821 cagttaactc aagaacaggt tgactacatt gtagcgaagg cctctgttgc tgctttggac
    29881 gcacatggtg agttagctaa gcatgcctat gaagaaactg gtcgcggagt ttttgaagat
    29941 aaggctacca aaaacctttt cgcatgtgag cacgttgtta ataacatgcg tcaccaaaaa
    30001 acagtaggta tcattgaaga agacgatgta acaggtttga ccttaattgc tgagccagta
    30061 ggtgttattt gtgggattac cccaacaact aacccaacgt caacagctat ttttaaatct
    30121 ttaatctcct taaaaacacg taaccctatt atttttgcct tccacccatc agctcaagaa
    30181 tcatcagctc atgcagcacg cattgttcgt gatgcagcca ttgcagcagg agctcctgag
    30241 gactgtgttc aatggattga aaccccatca ctagaagcaa ctaacgctct gatgaatcat
    30301 gatggtattg caacaatcct tgcaactggt ggtaatgcta tggttaaggc agcctactca
    30361 tgtggtaagc cagctcttgg ggttggtgct ggtaacgtgc ctgcctatgt tgaaaaatcc
    30421 gctaacattc gtcaggcagc acacgatatt gtcatgtcta aatcatttga caatggtatg
    30481 gtttgtgctt ctgagcaggc tgttattatc gacaaggaga tttatgacga gtttgttagt
    30541 gaatttaagt cttaccacac ttactttgtc aacaaaaagg aaaaggctct gttagaggaa
    30601 ttctgctttg gtgctaaggc taacagtaaa aactgtgcag gtgctaagct gaaccctaat
    30661 attgttggta agccagcagc ttggattgct gagcaggcag gctttacagt accagaagga
    30721 acgaatatcc ttgcagcaga atgtaaggaa gtttctgaaa atgagccatt aacacgtgaa
    30781 aaattgtcac cagttatcgc tgttttgaag gctgaatctc gcacagatgg tgttgaaaag
    30841 gctcgtcaaa tggttgaatt taacggactt ggtcactcag ccgctattca tactgctgat
    30901 gcagacttag ctaaggaatt tggaacaaaa attcgtgcta ttcgtgtgat ttggaattca
    30961 ccttctacat ttggtggtat cggtgatgtt tataatgcct tcctaccgtc attaacattg
    31021 ggctgtggtt cttatggacg taactcagtt ggtgataatg ttagtgctgt aaatctcttg
    31081 aacatcaaaa aagtaggaag acgtagaaat aatatgcaat ggtttaaagt tccttcaaaa
    31141 acatacttcg agcgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgagcgtgtg
    31201 atgattgtta ccgaccacgc tatggttgag cttggcttct tagatcgtat catcgagcag
    31261 cttgaccttc gtcgtaataa ggttgtttat caaatttttg cagatgttga gccagatcct
    31321 gatatcacaa cggttatgaa aggtactgag ctgatgcgta ccttcaagcc agatacgatt
    31381 atcgctcttg gcggtggttc tccaatggac gctgcaaagg taatgtggtt attctatgag
    31441 caaccagagg ttgacttcca tgatcttgtt caaaaattca tggatattcg taaacgtgcc
    31501 ttcaagttcc ctgagcttgg taagaaaaca aaatttgtgg ctattccaac aacctcaggt
    31561 acaggatcag aggttacacc gtttgctgtt atctcagata aggccaacaa ccgcaagtac
    31621 ccaattgctg actattcatt gacaccaacg gtagccattg ttgacccggc gttggtgctt
    31681 acagtaccag gcttcattgc agctgataca ggtatggacg tgttgaccca cgcaaccgag
    31741 gcttacgtat cacaaatggc taatgacttt acagatggtt tggcccttca agccattaag
    31801 attgtctttg aaaaccttga aaaatctgtt aaggaagctg actttgagtc acgtgaaaaa
    31861 atgcataatg cctcaacaat ggcaggtatg gcctttgcta atgccttcct gggtatttct
    31921 cactcaatgg ctcataagat tggtgcacaa ttccatactg ttcatggacg taccaatgct
    31981 atcttgcttc catacgttat tcgttacaat ggtacccgtc ctgctaaaac agcaacatgg
    32041 cctaagtaca attactatcg cgccgatgaa aaatatcaag acattgctaa gttgctagga
    32101 cttccggcat ctactccaga agaaggtgtt gaatcttatg ctaaagctgt ttatgatctt
    32161 ggctgtcgct taggcattaa gatgaatttc agagatcaag gaattgatga ggaagaatgg
    32221 aaggcacaca ctcgtgagct tgcttatctt gcctacgagg atcaatgctc acctgctaac
    32281 ccacgcttgc caatggttga gcacatggaa gaaatcatga atgatgctta ttatggttac
    32341 gcagagcgtc caggacgtcg gaaataatat caatcattaa tagtaaaaat aggagctgct
    32401 tggcttctat ttttttatct agctatgaaa agggctgtgt tagatgaaaa agtcggcagt
    32461 gccttgtgtt gagatagctt aactcagggg tagtttctca gatatcatat aaagctttta
    32521 agacaatggt tttacagagc attccatcag agggggaagc ttcatttgcc atattcataa
    32581 agtggctgat agttacgact tagctgcact tagcaattag ctgaagaaaa taacatgttg
    32641 cgtctatctg atgagcttta ttttctaata aaacaaggag tgattgcttt tttaatgatg
    32701 ttaatagcgt taaaaacctt tatatatcaa acaaaaacca aaataatggt attgtcagac
    32761 tttttctaaa attacccttt attaattgac aaagagggtg taaaaaatta tactaaaaat
    32821 gtaatcgatt acattttcta gactaaattt ggagacgttt tatgaaagca gctacatatg
    32881 ttgctccagg tcagctggag cttattgatc aaccaaaacc agagattctt gctccgacag
    32941 atgctgtggt tcgtttattg aaaacaacaa tctgtggaac agacttacat attttaggtg
    33001 gagatgtccc agagactact catggtacca ttttaggtca tgaaggtatt ggtattgtcg
    33061 agtcagtcgg ctctgcagtg aacaacttta aggtaggtga taaggttatt atttcctgta
    33121 tcacagcctg taatacctgc tattattgta aaaaaggaat tcctgctcat tgtgaaagcg
    33181 gtggctggat tctagggcat ttgattaatg ggacacaagc agagtatgtt catattcctc
    33241 aagcagatgg cagtctttat catgctccta aaaccgttga ggatgatgcc ttggttatgc
    33301 tgtcagacat tttcccaact tcctatgaaa taggcgttca gtctgcaaag gtaaagccgg
    33361 gtgatacagt gtgtatcgtt ggagcaggtc ctatcggact agcagctctt ttaacagcac
    33421 aattttattc accagctaag ctgatcatgg ttgacttgtc agaatcacgt ttagaagcag
    33481 ctaagcgctt tggagcaaca gatacgattt gctctggtga ccttgatgat attgtcaaaa
    33541 aagtccatga attaactgat ggtcgaggtg ttgatgttgc cattgagtgt gtaggctatc
    33601 ctgctacctt tgatatttgc caaaagatta ttgctattgg cgggcatgtt tctaacgttg
    33661 gtgtccatgg aaaaccagtt agtttggacc tacaggacct atggatcaaa aacattacaa
    33721 tgtcaactgg cctagtaaac gctaatacaa cagaaatgct attgaatgtg ttgaaatctg
    33781 gtaagattga tgcaactaag atggtaacac atcactttaa gctgtcagag gttgaaaaag
    33841 cctatgaggt ctttaaaaat gccggcagta ataacgccct taaagtgatt attgaaaatg
    33901 acattacagc ctaaaggaat aaggtataaa tagataaaag tgacaacagc atttggaatg
    33961 gtctagatgc tgttttttag ccaacttaac tggttaagtt tattttcaga aaactttcaa
    34021 gaaattggtt gacaaacctt gtgaaaaagt atacaataca aattgtaaac ggttgcaaaa
    34081 atagataaac cgagacttag aaattggagg catcctatga aggctgtagt tgttaaccaa
    34141 accagcagtg gtgtagaggt tgtagagcat gatgtaccat caatcggtca tggagaagct
    34201 cttgttaaag tagaatattg tggcgtatgt catactgact tgcatgttgc gcatggtgat
    34261 tttggtcagg ttccagggcg tatcctcggt catgaaggta tcggtattgt cgaaaagcta
    34321 ggtgaaggcg ttacctcctt aaaggttggt gatcgtgtat caattgcttg gttctttgaa
    34381 ggctgcggtc attgtgaata ttgtacaaca ggtcgcgaga ctctatgccg ttcagtcaaa
    34441 aatgctggct attcagttga tggtgggatg agtgagtatg cagttgttac agctgactat
    34501 gctgtgaaag tgccagatgg tcttgaccca gctcaagcat catcaattac ctgtgcaggc
    34561 gttacaacct ataaggctat caaagaagca ggtgccgctc caggacaatg gattgttatc
    34621 tttggtgccg gtggacttgg taacctagct gttcagtatg ctaaaaaggt tttcaatgct
    34681 catgtcgtag cagtggacat taacaatgat aagctagagc tggccaagga ggttggagca
    34741 gatatcgttg tcaatggtaa agaaatcgaa gatgttgccg gctatatcca agaaaaaaca
    34801 ggtggtgctc atggcgttgt ggtaaccgct gtttctaaag tagcctttaa ccaagctatt
    34861 gatagtgtgc gtgcaggagg aactgttgtt gctgtaggac ttccatcaga atacatggaa
    34921 ttatctatcg taaagactgt cctagacgga atcaaggtag tcggatcact tgtgggaact
    34981 cgtaaagact tggaagaagc ctttgccttt ggtgcagaag gtctggttgt gccagttgta
    35041 gaaaaggttc cagttgagac tgctccagaa gtctttgacg aaatggaacg tggtctcatt
    35101 caaggaagaa aggtattgga tttcacgctt taaggctgat ttcagaaaaa gtcagcagcc
    35161 agacaagctg attgtcccaa atgatgaata aagtccttag aattaatttt ctaagggctt
    35221 ttttggtgaa actaactggt aaaaaaagct tggtatctaa agatgtaaaa gagccagcta
    35281 gttattaata ccatgattgc cccttgaaag acagtaccag agaaagttgg acatattgta
    35341 acctctgata gagatactgg gtttgaacaa tattagagat taacacagga actcaatcta
    35401 gaagtttatt tctctgctcc tcacacccct tgataacgta ggacaaatga aaataccaat
    35461 gggttaatca aagagtagtt tcctaaagga actgacttga ctgatattga gagctctatc
    35521 atataagagt gggaagataa atgaaatgat cgttctagaa gatgtcctaa ctggaaacta
    35581 ccttataaac tcttttatgg aaaagcgttg cacttaattt gacaattcgt cttcacaaat
    35641 tttaggaagc actgtaggaa aaaagaataa tgacataaca tattgctaaa aacatgggtt
    35701 ataagctaaa ttattatcta cgtttttagt aacaaggtag tatgatttaa aatatagatg
    35761 aaaaatgttg tgtcccgaat aagggaagtt ttttaggata cgatacttgt acattataat
    35821 ttatttataa aatcttttag gtggatttat gaaagaaatt gtaagaagtc atagattgtt
    35881 atatgtaata gtagcttttt ttagtgtaat cagtgcattt ttaatgacct tattttctat
    35941 tcaactggga aaaatactag atagtatatc taattcaagt agtgaattat tgtttcagat
    36001 agtagtgtgt gtatgtacca taatggcatg gtttataatg atatggtcct attcttattt
    36061 taagagttat tatgtaaaaa aggtcatttt agatttaaag gagaggcttt ttataggtta
    36121 tttattacgg gaatttaatg aaattgatac ttgtgatcga tataattcgg attttctaaa
    36181 caatgtaaca aaaaatattg atataattca ggagaattta ttggttccta gagtggctgt
    36241 gattgttgat ctggcttcaa tggttacgag tgtagtagct attgtactta tagaatggcg
    36301 attggcccta gtatttttat tgctttctat tgtaactgtt tttctatctc aaattcctgg
    36361 aaagttaatg agtaaagcaa ctcgatatta ttctgaaaaa agtaatcact atttagcaga
    36421 aatgactagt tttattgagg gatttgaaca gattaaatta ttgaatattc aaaaatggat
    36481 acaaaaaatc gaacaaaata ctactttaga atttgaagat tctagacaga aatatcaata
    36541 cagaaaagat ttagcttcaa atacaggaat gtttttgagc ttcttttctc aagtagcctg
    36601 tatggttgct ggtatatttt ttgtaaggaa taatctacta acagttggac tattagtggc
    36661 cagtattcag ttattaaatg gagtgtttgg ccctctacag tctttccttt acaataaaaa
    36721 tttgatcaaa agcacaggta ctattttaac aagtattcaa gaagttctag ataaaacaaa
    36781 ttttgttaat ggttatatag aaaataagac tttttatgaa ggagacatct ccagcatttc
    36841 gataaataat ttaacttatc aagttgaaaa tagaaaaata tttactaatt tttcatttga
    36901 atttaaaaag ggaaatactt atgccattat tggtccttcg ggggttggga aaacaacatt
    36961 agcaaaactg atattaaatt attatccaaa gcatttatat gatggggaaa taagaattga
    37021 tggaagaaat attgctgaaa ttaactcaga aagtttgtat aagaagattg cgtttgttca
    37081 aaaaaatgat tttcttgtgg aaggtaatgt ttcagacaat attaaattag atgggagttt
    37141 gaatctaaca gacaagctca aagatagttt aggatttgat gaaacatttt taaacaaaaa
    37201 attatttaga gttcagtctt taatctcaga aggagaaaaa caaagaattg atttagcaag
    37261 atttttaaac cgtagatatt ctatttatat ttttgatgaa ccaactggta atcttgatcc
    37321 agctagatct aaagccatat tggattatat tttatcaata aagaatgcaa tcatcattgt
    37381 gattactcac aaccaagata taaaaacgtt agaacaattc gatgaagtca tttgtttgta
    37441 aatgaaaggg ggtgatgaac atgattatgg aagattttga agttttagaa ctagagtttg
    37501 tcgaagttcg aaatgaacaa accacaaatt ggtattttgt ttaatcacaa aggcatgcaa
    37561 tgagaatttg catgcctttg taaaatatag aaaggacaat aaaatgaata atttttttcc
    37621 aaaatggaat caggatagga ttgtatattc atggcaaaat gataaattaa ggataggagc
    37681 tgatgataat gatgttctag aaatcaaagg aaactcaatt ttttggtcag attttatttc
    37741 ttgttgtgac gggaataata gtatcaaaga cattcaaaaa ctattgaata taaaatataa
    37801 tatttcagaa gaaataatta cagagtattt agataaattc tcaaatcgaa atttattgga
    37861 aatattggat aatccaataa atcaattaca ggattataaa tcaattgagt cgttagaaac
    37921 atattatgct agtgaaggaa ttggtgggat taaactatta aaaatgttag ggaatctaaa
    37981 gatttctatt ctgggatgtg gtggtggtgg atctcatatt gcattacaat tagctcaatt
    38041 aggagtggga agaattcatt tggtggatta cgatattgtt gaagaaaaca atatcaacag
    38101 acaatccatg ttcacattta acgatgtcgg aaattacaaa gttgattgtg tagccaaaaa
    38161 tattcagcaa agaaattcta aatgtttggt taccaaaagc acttctaaaa tgattaatgt
    38221 acctgatgta aaaaaaagaa atatctgaaa gcgattgggt attctgttgc atggatgaac
    38281 ctccttatat agcacagagg attgtaaata gagcatgtta tttattaaaa attccaagta
    38341 tatactgttt tagccaacgt agtgcgggga aacttttgtt ttgtaatcct aatattgaag
    38401 attctggctg tattgattgt ttgttatctg aacaagataa tgaaaacttt caaaagctgg
    38461 tgacaacgtt cactacctat aataggaaat tggtaactgc aaatatctta ccaaatattt
    38521 tattattgac atcgtgggtg gttaaacgat ggttagattg tgtaacagat aaaaatagta
    38581 atgtatggaa tatgttgttg agatttgatt tttataaata tatggaagaa aaatttcaat
    38641 atttttcgaa acaagatagt tgtccaacat gtgctaaggg tcttagtaca agtaaattat
    38701 gggagatttt aaaaatagat gaataaaaaa attattttta aaggtgatca agatagtaaa
    38761 tttgcttatt tttcattgat gttttctgca ggtactgcca ttgaaaatac agaagaactt
    38821 ggtttttcac atttgataga gcatttatta ttacgatcag gcggagaaca atcattaaat
    38881 gaactatttg ataataatgg tgcatttatt ggaggtgaaa cttctagaga ttatattaat
    38941 ttgatgggtt actgtaaggc tgaaaatttc aaaaatatat ttgaagcaat agtaagtagg
    39001 gtatttaatt taaatcttac tgaagaagaa ctgctaagag aaaaaagggt agttttagtt
    39061 gaactaacac agtacgagaa tgggagcaaa acagaaaaat tagtttcgga taaccgccta
    39121 atttttaaaa atagtaagtg gtcagaagat attattggtg ttagggagaa tattgaatct
    39181 gttgatttga aaaagcttta taagttttac actgagaata tccaaaacgg agaatttcaa
    39241 attgctattt caggaccgaa tcacttaaaa gaagaaatag cgattattga aaataaatta
    39301 ccagttggaa gaactcctgt taaatctaat tttcctattt tttctagtgg tgtaacagaa
    39361 cgaaagaaaa atcaacaggt ttctgaaatt tcaatgtata ttgatatttc aaaaatgaca
    39421 acatcatctc atgatgtagc gatattaaca attttaaatg cgatgttaac aggagttaag
    39481 ggttcagtgt taggaggtaa attaaggacg aaaaaccaat gggtatataa tataatttca
    39541 ttcccaatct tttacaatgg gctcactatc ctaaagatac tgactagaac gcctgaaatt
    39601 cataagcatc aagtagtaca agttctaaaa gaagacttag taaatagaga agacttaaaa
    39661 aatacgaaat tatttgataa agctaaaaaa agagttatca atgaagttct tatgagctat
    39721 gaagtgaaga aagtcgagtt tttaaagaca ctttgcaggg agaaattatt taatatacct
    39781 agttgggaga gtgttactgg ggaaattgag aaagtttctc tcaatgaact taatcaattt
    39841 gctaaagatg ctctcatgca aaacaagcaa tttcatatca taataaattg ctaatatatt
    39901 tgttaaagtg ttcttgataa ttttgataaa ttgttttatt taaagaattg aagattttta
    39961 aggcttcttc tatcttagag tttgattttt ctgtgtgaat attaaatttc aactctaggt
    40021 atccttctag gtataacaat atagttaact caaaaaaata agttgagtta gataacaggt
    40081 ttttactagc ttgatttaaa aatattgctt cttcataaaa atcattttca atcattaata
    40141 gaagactatt aaggagtagt tgaattagcg actgtttatt acgaggaatt gaattgtata
    40201 attttccttt ttttagagct tccttagtat acttgaataa tagtttagga ggtaaagaac
    40261 gacagcaatt tccaagaata agggtttcat agtatcccca attttctaag gaaaataaat
    40321 aatttgaaag ataagagata tcttgattag ttaattggtg attgttatca agtccagaaa
    40381 tgatactttg gataaaaatt gaatttaatt tatgataatg agagtttgtc tcttcaaaca
    40441 atttattttc ttgttctatc atacttatta gtgtttcgac tttattattg tatgcagaat
    40501 tttgaacagc ttttattagt gtattaaatt cagatggttc ataattgtta caggcgagca
    40561 agaattcttc aaaggttatt ccgagttttt ctagtaaata taataacttg aaaatagaaa
    40621 tttccgtctc tcctaattca aatcttgaaa tttgagattt tgaaatttca tatcctgcta
    40681 atgaagaaat agaaattcct ttttcttccc gcatttttct ataggtttca cctaagatca
    40741 tagattatct ccgtttgtag ttaaaaagtg gaaagcgtga caaatgatga gaaaaagtta
    40801 caagttactt aaattgattc ttgatattat cattattata ggtttatgtc aataattttt
    40861 gtagattgca tgaagtataa tgcctataag tttttagtac tcaattttat gatttaatat
    40921 ttaaattaag caatagtcaa gtcacctttc actaagaaaa atcacttgat tattgcttag
    40981 ttttttctaa tggaggattt ttagtttaga agctttgagt ttagacctca aaacttagat
    41041 atggaattcg aaaggcagtc actgctgtca acattacttt gggaaagttc ctataagaga
    41101 cttttcatta gactgaagta gcttcaatag ctctaaaact acctagactc aagtaacaac
    41161 aagtccttag aattgatttt ctaagggctt ttttgctgcc tcaaggtaaa gacatgttca
    41221 gcaacaaatt gactggctag accagtcctt tatttatgct gatggcttga gactgctggg
    41281 ttattagcac agaaaatggc tgtctccaaa tcctagaagg cttatgattg gaatatgata
    41341 taatagtcaa aagaaatgat gaggtgatgt gaagcaatgc caatgatgta ccaatcaaca
    41401 agaaatgcag ctaataaggt aacagctagt caagcgattt taagtggcct agcagatgat
    41461 ggtggcttgt ttactcctac aagcatgcca gtgctggatc tagattttga ggagctaaag
    41521 accaagtcct atcaagaggt tgccaagctt attttatcag ccttttttga tgactatact
    41581 gaagcagaat tagatgcttg tatctcttct gcctatgatg ataagtttga tacagcagtg
    41641 atagcacctc tagctacgtt aaaggattat cataatttgg agctatttca tggctcaacc
    41701 atcgcattta aggacatggc tctatctatt ttgccttatc tcttgacaac tgctgctaaa
    41761 aagcaaggtg tggagcgaaa aattgcgatt ttaaccgcta cctcaggtga tactggtaag
    41821 gcagcaatgg caggctttgt tgatgttccg ggaacggata ttattgtctt ttatcctaag
    41881 tcaggcgtta gcaggattca ggagctgcag atgatcacac aggccggtca caatacccat
    41941 gttgtggcga ttgaaggcaa ttttgatgat gctcaaacag aggtcaagcg cctgtttaat
    42001 gaccctgatt tgcgtgagcg gctagcagct caacagatac agctgtcttc ggccaattcg
    42061 atgaatattg gtcgtttgat tcctcaggtt gtctattata tttatgctta tgcccagttg
    42121 gtaaggcatc agcgacttga agctggagag acgattaaca tagtagtgcc gacaggaaat
    42181 tttggcaatc tactggttgc ctactacgcc aaagaaattg gacttcctgt tgccaaattc
    42241 atctgtgctt ccaatgaaaa caatgtcttg acagatttct ttgctagtgg taggtatgat
    42301 aaaaagcgtc ccttcaaggt gactactagt ccatcaatgg atattttggt gtcttcaaat
    42361 ttagagcgct tggtttttta tttactaggc aatgatgccc aaaagacagc agtattaatg
    42421 aagagcttgg cagaaacagg tcagtatcag ctagctgatg cagatcagtc tatccttgat
    42481 ttatttgcgg caggctttgc aacagagcaa gagactgcta aagagatcaa aacgatattt
    42541 gagtctgatc attatgtgct tgacccacat acagctgtag cttcagctgt ttatcgtgct
    42601 tatcgggagc aatcaggtga ctctagaccg actattgttg cgtcaactgc tagtccttat
    42661 aagtttccgc gggtagttgt ggaagctatt agtggtcagc aggttgccag tgattttgag
    42721 gcgcttgagc agttggctga tatatcaggt gtagtcgtgc cacaagcggt caatggctta
    42781 caggaggcgc ccattcgtca tagcctttta gtgacagtag cagatatgca gcaggcagta
    42841 gaggcttatc ttggagtata ggaggcataa aggagctccc tttcaattga tatgaatata
    42901 atgactcaca atagaaaaaa gatactgtcc ttggcccttc catcaatggc agaaaatata
    42961 ttgcaaatgc tgatgggaat gatagacaat tatttggctg ctcaaattgg acttacggct
    43021 gtttcaggca ttgcgattgc taataatatt ctgacgattt atcaggccct ttttatcgca
    43081 ttaggtgctg cagtctccag tctcattgct agaagcgtag gagagcaaaa ccattctaaa
    43141 gaaatcgact acatggcaaa tgctatctta gtaacggggg ctctatcagt tcttctaggc
    43201 ttgatgtccg tagtgggaca taaaagcata ttagcctttc tgggagcagc tagtctggta
    43261 gctagacttg gtgggcagta tttagccatt gtcggtggaa tgattcttag tcttggtctt
    43321 ttcacgagct taggtgcgat tattcgtgct aagggccagc ctagcattcc catgaaggtc
    43381 agccttttaa ctaatttgct aaacgctgta ttttcagccc tttctcttta catatgggga
    43441 tttggagtga tagggattgc ttggtcaact gttgcatcac gtctcattgg agttgttatt
    43501 ctatgtcact ttcttcctat taaagaaatt attaaacgtt ttgctaatcc cttagataaa
    43561 gagatcttta gcctctctct tccagcggct ggtgagcggc tcatgatgcg agctggtgat
    43621 gtgctgattg ttactattat tgttagattt ggaacagagg ccttggcagg caatgcgatt
    43681 ggagaaacct taactcaatt taattatatg ccgggacttg ctatgtcaac tgcgacagtc
    43741 attttagttg ccaatcagtt gggcagtggc aaaggggcta caatagcgaa aactgtaaaa
    43801 gaaacctttt tgttagccac cctgatgatg cttgttatgg gcttgatcac ttatttgcta
    43861 ggccctaatc tactgccctt atttacagca gatgccaagg ctcagcaggc tggtatggtt
    43921 gtcttagtct tttctctttt gggggtacca gcaacagccg ggaccttggt ttatacagca
    43981 gcctggcagg gtatcggaca agctaagctt cccttttatg caacaacgat tggtatgtgg
    44041 ctggttcgga tttctttggg ctactttatt ggagtaacct taaattatgg agtaataggt
    44101 gtttggcttg cgactatttt ggacaatgct accagatggc tcattcttgc agtggctttt
    44161 aagaagcagc aaaggcagct tttttcggac tgtcatagct aaactttgta tttaggtctc
    44221 aagacttctg agtggtgact ttccttttgg gagtcagcca ctgtcatcag aatgtaaagt
    44281 acgcctgagg ctctgtttgc taatagcttc tcttatctgc ggaagatcaa agaggattgc
    44341 tggaacagct gaggtttgtc ttcaatctgg cttgcccttt cttagggcaa gtttttttga
    44401 aaaaatcccc tgaaaggctt gcaatgcctt attaattctg ctattatatt atggtgctgt
    44461 aaaaatacag ctttagctgt gatacgagag gttgcgacac gctcggttgc attgccacgt
    44521 gacaggtgtc ggttttctcg aggagctagc ctattatcgt aaatagacga gaggagaaaa
    44581 gatggcaaac aaaaaaatcc gtatccgctt gaaagcgtac gaacaccgta cacttgatac
    44641 agcggcagaa aaaatcgttg aaactgcaac tcgtacaggt gcaacagtag ctggaccagt
    44701 tccacttcca actgaacgta gtctttacac cattattcgt gcgactcaca attataaaga
    44761 ttctcgcgaa caatttgaaa tgcgtacaca caaacgtctt attgatattg tgaacccaac
    44821 gcaaaagact gttgatgcac ttatgaaatt ggaccttcca agtggtgtca acgtagaaat
    44881 caagctttaa ttgtttgaaa catgagtgag gaacgagttc atatctaatt gaacacaggc
    44941 taaactctgt gtgaaaaaga gacacagccg ttctaatttt aattagatta cggatgtggc
    45001 tacctgtagg tgtaaatctt cctagaaaca gaagtttctt cgtcagattt cctattttca
    45061 ctgtgagttt gacgccttaa gtatcttgct ttgagcataa aaaacgctcg taaaaaactt
    45121 ttttgagcat aaaaaacgct cactaaaaac tttttgaaat attattaaga aaaggaatta
    45181 ttttctcatg acaaaaggaa tcttagggga aaaagtggga atgactcaaa tcttcactga
    45241 atccggtgaa tttatccctg ttactgtcat cgaagcaact ccaaacgttg tgcttcaagt
    45301 taagactgtt gaaacagacg gttacgaagc aattcaagtt ggttttgatg ataaacgtga
    45361 agtattgagc aacaaacctg ccaaaggcca tgtagcaaaa gctaacacag ctcctaagcg
    45421 cttcattcgt gaattcaaaa acattgaagg cttagaagta ggtgcagaaa tcactgtgga
    45481 tatcttcgca gctggggatg ttgttgatgt aactggtact tcaaaaggta aaggcttcca
    45541 aggtgttatc aaacgccatg gtcaatcacg tggtccgatg gcccatggtt ctcgttacca
    45601 tcgtcgtcca ggttctatgg gacctgtttc accaaaccgc gttttcaaaa acaaacattt
    45661 ggcaggacgc atgggtggca atcgtgtaac tattcaaaat cttgaaattg tacaagttat
    45721 cccagaaaag aacgttattc ttattaaagg taacgtacca ggtgctaaga aatctcttat
    45781 caccatcaaa tcagcagtta aagctgctaa ataataagaa aggagaaaac agttaaaaat
    45841 ggcaaacgta aaactatttg accaaactgg taaagaagtt agcacagttg aattaaatga
    45901 tgatatcttt ggtatcgaac caaacgaatc agttgttttt gatgttgtaa tcagccaacg
    45961 tgctagcctt cgccaaggta ctcatgcggt taaaaaccgt tcagcagtat caggtggtgg
    46021 acgtaaacct tggcgtcaaa aaggaactgg acgtgctcgt caaggttcta tccgctcacc
    46081 acaatggcgt ggtggtggtg ttgtctttgg accaactcca cgttcatatg gatacaaact
    46141 tccacaaaaa gttcgtcgcc ttgctttgaa atcagtttac tcagcaaaag ttgctgaaga
    46201 taaatttgta gctgtagaaa gcctttcatt tgcagcacca aaaacagctg aatttgcaaa
    46261 ggtgctttca gctcttagca ttgatacaaa agtacttgtt cttgttgaag aaggaaatga
    46321 atttgcagca ctttctgcac gtaaccttcc aaacgtagct gtggcaacag cagcgactgc
    46381 aagtgttctt gatatcgtaa acgcagacaa acttcttgta acgaaagaag caatctctac
    46441 aattgaggag gttcttgcat aatgaatttg tacgacgtaa tcaaaaaacc agttattact
    46501 gaaaaatcaa tgtatgccct tgaagaaggt aaatacacat ttgaagttga cacacgtgcg
    46561 cacaaactgt taatcaagca agctgttgaa gctgcatttg acggagttaa ggttgcaagc
    46621 gtcaatactg ttaacgttaa accaaaggct aagcgtgttg gtcgttacac aggttttact
    46681 tcaaaaacta aaaaggctat catcactctt acagctgatt ctaaagcaat cgagttgttc
    46741 gcagttgaag ctgaataatc taaggaggaa ataacgtggg tattaaagtt tataaaccaa
    46801 cgacaaatgg ccgtcgtaac atgacttctt tggatttcgc tgaaatcaca acaagcacac
    46861 ctgagaaatc attgcttgtt tctcttaaaa acaaagctgg tcgtaacaac aatggtcgca
    46921 ttacagttcg tcaccaaggt ggtggacaca aacgccatta ccgtttgatt gacttcaagc
    46981 gtaacaaaga tggtgttgaa gcagttgtta aaacaatcga atacgatcca aaccgtactg
    47041 caaacattgc acttgtacat tacactgacg gagttaaggc ttacatcatc gctcctaagg
    47101 gtcttgaagt aggtcaacgt attgtttctg gaccagatgc agatattaag gttggtaatg
    47161 cacttccatt agtaaacatt cctgttggta cagttgttca caacattgag cttaagcctg
    47221 gtaagggtgg agagcttgta cgtgctgctg gagcttctgc tcaagtactt ggtcaagaag
    47281 gcaaatacgt tcttgttcgt cttcaatcag gtgaagttcg tatgattctt ggaacatgtc
    47341 gtgcaactgt tggtacagtt ggtaacgagc aacaatcact tgttaacatt ggtaaagcag
    47401 gacgtagccg ttggaaaggt atccgcccaa cagttcgtgg ttctgtaatg aaccctaacg
    47461 atcacccaca tggtggtggt gaaggtaaag caccagttgg acgtaaagcg ccatctactc
    47521 cttggggtaa accagcgctt ggtcttaaaa cacgtaacaa aaaagctaaa tctaacaagc
    47581 ttcttgttcg tcgtcgtaac gaaaaataag cggcaaatct agcataagct tattcaatca
    47641 ttccgccagc tcggtagagt ttgagcttgc tctcatgctc aagccgctgt ggtacattat
    47701 ttaaaggaga aaactacaaa atgggacgta gtcttaaaaa aggacctttc gtcgatgagc
    47761 atttgatgaa aaaagttgaa gctcaagcta atgacgaaaa gaaaaaagta atcaaaactt
    47821 ggtcacgtcg ttcaacgatt ttcccaagtt tcatcggata tacaatcgca gtttatgatg
    47881 gccgcaagca tgtacctgtg tacattcaag aagacatggt aggtcacaag cttggtgaat
    47941 ttgcaccaac tcgtacctac aagggtcacg cagctgacga caagaaaaca cgtcgttaat
    48001 aggaggagga cacaatggca gaaattactt cagctaaagc aatggctcgt acagtgcgtg
    48061 tttcacctcg taaaacacgt ttagtacttg atcttatccg cggtaagaaa gttgctgatg
    48121 caatcgcaat cttaaaattc actccaaaca aagcagctcg tgttattgag aaaactctta
    48181 actcagcaat tgctaacgca gaaaataact ttggtttgga aaaagctaac ttggtagtat
    48241 ctgaaacatt tgcaaacgaa ggaccaacaa tgaaacgttt ccgtccacgt gcaaagggct
    48301 cagcgtcacc aatcaacaag cgaacaactc acgttacagt agttgtatca gaaaaataag
    48361 gaggtaaaat cgtgggtcaa aaagtacatc caattggtat gcgtgtcgga atcattcgtg
    48421 actgggatgc aaaatggtat gctgaaaaag aatacgcgga ttaccttcat gaagatcttg
    48481 caatccgtaa attcattaac aaagaattgg cagaggcttc agtttcaaca attgaaattg
    48541 agcgtgctgt aaataaagtt attgtttcac ttcacactgc aaagcctggt atggttatcg
    48601 gtaaaggtgg agcaaatgtt gacgctcttc gcgctcagct taacaaatta actggaaaac
    48661 aagtacacat caacatcatc gaaatcaaac agcctgatct tgatgcccac cttgttggtg
    48721 aaaacattgc tcgtcagctt gagcaacgtg ttgctttccg tcgtgctcaa aaacaagcta
    48781 ttcaacgtac aatgcgtgct ggagctaagg gaatcaaaac tcaagtttca ggtcgcttga
    48841 acggtgcaga tatcgcgcgt agcgaaggct actcagaagg aactgttcct cttcacacac
    48901 ttcgtgcaga tattgactat gcttgggaag aagcagatac tacatacggt aaacttggtg
    48961 ttaaagtttg gatttatcgt ggtgaagttc ttccagctcg caaaaacact aaaggaggca
    49021 aataacagat gttagtacct aaacgtgtta aacaccgtcg tgagtttcgt ggaaaaatgc
    49081 gcggtgaagc aaaaggtgga aaagaagtat cattcggtga atatggtctt caagctacta
    49141 ctagctcatg gatcactaac cgccaaatcg aagctgctcg tatcgctatg actcgttaca
    49201 tgaagcgtgg tggtaaagtt tggattaaaa tcttccctca caaatcttat acagctaaag
    49261 ctatcggggt tcgtatgggt tctggtaagg gtgcacctga aggttgggta gcaccagtta
    49321 agcgtggcaa ggttatgttt gaggttgctg gtgtttctga agaaatcgct cgtgaagcac
    49381 ttcgtcttgc tagccacaag ctaccagtta aatgtaaatt cgtaaaacgt gaagcagaat
    49441 aaggagaaga catgaaactt gaagaaatca aaaagtttgt tgctgagctt cgtggcttgt
    49501 ctcaagaaga gcttgctaag aaagaaaacg aactcaaaaa agaacttttc gaccttcgtt
    49561 ttcaagctgc agcaggtcaa ctagatcaaa ctgctcgttt gaacgaagtt aaaaaacaaa
    49621 ttgcacgtgt aaagactgtg caatctgaaa tgaaataata gattgggaaa ggagtattct
    49681 aaataatgga acgtaatcaa cgtaaaaccc ttgttggacg tgttgtatct gacaagatgg
    49741 acaaaacaat cactgttata gttgaaacaa agcgtaacca cccagtctat ggtaaacgta
    49801 tcaactattc taaaaaatac aaagcacatg acgaaaagaa ccttgctaaa gaaggcgata
    49861 tcgttcgtat catggaaact cgtccacttt cagctacaaa acgcttccgt cttgtagaaa
    49921 tcgtggaaga agctgttatt atctaatcaa actaaaagga gacaattgaa atgattcaac
    49981 aagaaactcg cttgaaagtt gctgataata gcggtgctcg tgagatcttg actatcaagg
    50041 ttcttggtgg ttcagggcgt aagtttgcta acatcggtga cgtcatcgtt gcatctgtaa
    50101 aacaagctac tcctggtgga gcagttaaaa agggtgatgt tgttaaggct gttattgttc
    50161 gtacaaagag tggtgctcgt cgtccagacg gttcatacat caaatttgat gacaatgcgg
    50221 ctgtcattat tcgtgatgac aagactcctc gtgggactcg tatctttggg cctgttgcac
    50281 gtgaattgcg tgagggtggc tacatgaaga tcgtatcact tgcaccagaa gtactttaat
    50341 tttaatcatt aaacaaacta agtcccctag gctagcctag ggtgcccata ggggcgtaag
    50401 aaaataatag gagaaaccca taatgtttgt aaaaaaaggc gacaaggttc gcgttattgc
    50461 tggtaaggac aaaggtgttg aagctgttgt tcttaaagca cttccaaaag taaacaaagt
    50521 tattgttgaa ggcgtagcca tcatcaaaaa gcatcaaaaa ccaaacagcg aaaatcctca
    50581 aggtgctatc gttgaaaaag aagcaccaat ccatgcatca aacgttcaag ttcttgataa
    50641 aaatggtgtt gctggacgcg ttggttacaa gtttgtagac ggcaaaaaag ttcgttacaa
    50701 caaaaaatca ggcgaagtgc ttgattaatc acgaaggaaa ggagaagcat aatggcaaat
    50761 cgtttaaaag aaaaatatac taacgaagta attcctgcgt tgacagagaa gtttaattac
    50821 acatcagtta tggctgtgcc aaaggttgag aaaatcgttc ttaacatggg tgtgggtgac
    50881 gctgtatcaa acgctaaaaa ccttgaaaaa gctgctgcag aattggcgct tatctcaggt
    50941 caaaaaccac ttattactaa agctaagaaa tcaatcgctg gcttccgtct tcgtgaaggt
    51001 gttgctatcg gtgcgaaggt gacacttcgt ggcgaacgca tgtacgaatt cctagacaag
    51061 ctagttagcg tttcacttcc tcgtgttcgt gacttccatg gtgttccaac aaaatcattt
    51121 gatggtcgtg gtaactacac tcttggtgtg aaagaacagc ttatcttccc agaaatcaac
    51181 tttgatgatg ttgataaagt gcgtggtctt gatattgtta tcgtaacaac tgctaacact
    51241 gacgaagaat cacgtgaatt gcttaaaggt cttggaatgc cttttgcaaa ataatagggg
    51301 gtaactaaat tggctaaaaa atctatgatt gctaaaaaca aacgtcctgc gaagtattct
    51361 acacaagctt acactcgttg tgaaaaatgt ggacgtccac attctgttta ccgcaagttt
    51421 aagctttgcc gcgtttgctt ccgcgagttg gcttacaaag gccaaatccc aggtgttgtt
    51481 aaagcgtctt ggtaaaatga tgatgtgaga gcgttaagct acctaagcaa aaataggaaa
    51541 attgacgaag agtctaaata ctctaggaaa ttttgcacct aaaggtagta gcttgaactc
    51601 agttcaaatg aacaaataat actatcagat attatgtctg attcgatgca aaggcaaagt
    51661 gtcaatttga acacgggcga aagccggtgt caaaaagata aacattcctt ggaggttttc
    51721 cctcctgcgg aagtttccta ttttgacttt ggcttttagc gccctttgta tcatcgatta
    51781 actagcaagt gcagcttgca aactactagt aagaggagaa taataaaatg gttatgactg
    51841 acccaattgc agactttttg acacgtattc gtaatgctaa tcaagtaaag catgaagtgt
    51901 tagaagtacc tgcatcaaat attaaaaaag ggattgcaga aatccttaag cgtgaaggct
    51961 ttatcaaaaa cgttgaagtt attgaagatg gcaaacaagg aattattcgc gtatttctta
    52021 agtacggtca aaatggtgaa cgtgtcatca ctaacttaaa acgtgtttca aaaccaggtc
    52081 ttcgtattta ttctaagcgt gaggatgttc caaaggttct taatggacta ggaattgcaa
    52141 ttatttcaac ttcagaaggt cttttgactg ataaagaagc tcgtcaaaag aacgttggtg
    52201 gagaagttat cgcatacgtt tggtaattta agagacaaaa gccgtaacga acaatctaaa
    52261 attagaaaat tattgtggct tgcttgcaaa caaaatagtt tgtctatttt agatggcagt
    52321 tcgtcggctg tgctcaaatg atgaacacta tcaacatagc aaacgtaaaa gaactaattg
    52381 aacatgggct aaagtctgtg tgaaaaagat aaatttttct agaaaccttg gtttcatagt
    52441 aatgtttcct attttcactt tgccttttac gccctaagta tcttagttca ccccgtgaaa
    52501 actcgtcgcg taagcggcct gataatttaa caggagaaaa aattaatatg tcacgtattg
    52561 gtaataaggt tattattatc cctgcaggcg ttgaaatcat taacaacgac aatgttgtta
    52621 ctgtaaaggg gcctaaagga gagctcactc gtgagtttaa caaaaatatt gaaatcaaag
    52681 tcgaaggaaa cgaaatgact cttgtacgtc ctgacgactc aaaagaaatg aaaacaattc
    52741 atggtacaac tcgtgcaaac ttgaataaca tggttgttgg agtttcagaa ggtttcaaaa
    52801 aagagcttga aatgaagggt gtcggatatc gtgcacagct tcaaggctct aagcttgttc
    52861 tttcagtagg taaatctcac caagatgagg tggaagctcc agaagggatt acatttactg
    52921 tagctaatcc aacatcaatt tcagttgagg gtatcaacaa agaagttgtt ggtcaaactg
    52981 ccgcttacat tcgtagccta cgttcaccag agccttacaa aggtaaaggt attcgttacg
    53041 ttggtgagta tgtacgcctt aaagaaggta aaacaggtaa ataatgttct tagtggaata
    53101 tggcataggc ttgcttatgt catgctctac aagctcaatt gataatttgt cggaaagaca
    53161 aacttaaata ttaagaggtg aaaattgtga tttcgaaacc agataaaaac aaaatccgcc
    53221 aaaaacgcca tcgtcgcgtt cgcggtaaac tctctggaac tgctgatcgc ccacgtttga
    53281 acgtattccg ttctaataca ggcatctacg ctcaagttat tgatgacgta gcgggtgtaa
    53341 cgctcgcaag tgcatcaact cttgataaag aagtttctaa aggaacaaaa actgaacaag
    53401 ctgttgtagt cggcaaactt gttgctgaac gtgcggtggc taaaggtatt tctgaagtgg
    53461 tgtttgaccg cggtggatat ctctatcatg gacgtgttaa agctttggct gatgcagctc
    53521 gtgaaaacgg attgaaattc taatagggag gacacaaaat aatggcattt aaagataatg
    53581 cagttgaact tgaagaacgc gttgttgcta ttaaccgcgt tacaaaagtt gttaaaggtg
    53641 gacgtcgtct tcgttttgca gctcttgtag ttgttggtga tggaaacgga catgttggat
    53701 tcggtactgg taaagctcag gaagtaccag aagctattcg caaggcagtt gaagctgcta
    53761 aaaagagcat gattgaagtg ccaatggttg gcacaacaat tcctcacgag gtttacacta
    53821 actttggtgg agctaaagta ttgttgaagc cagctgtaga aggttctgga gttgctgctg
    53881 gtggtgcggt acgtgccgtc atcgaattag caggtattgc tgatattact tcaaaatctc
    53941 ttggttcaaa cactccaatc aacatcgttc gtgcaactgt tgaaggatta aaacagctta
    54001 aacgtgcaga agaagttgcc gcacttcgtg gcatctcagt ttctgactta gcttaagaaa
    54061 ggggatcatc atggctcaaa ttaaaattac tttgactaag tctccaatcg gacgtaagcc
    54121 agaacaacgt aaaacggttg ttgcccttgg acttggtaaa ttaaactctt cagttatcaa
    54181 ggaagataat gctgctattc gtggtatggt gacagcaatt tctcacttgg tgacagttga
    54241 agatgtcaaa taaagagtta gctagaaatc tctgatttct tgcattagca tgcagaaccg
    54301 gcttttgtga gttattcctt tgaatgacaa gcagtggtcg gttggtgcat atagcatcag
    54361 gctatgacat agcttgatca tgtataggcg agtttctatg gagagtcctt tcccttcata
    54421 gaggcgctag cattttacaa aaaaaggaga aaaaatgaaa cttcatgaat tgaagcctgc
    54481 caaaggctct cgtaaagtcc gcaatcgtgt tggacgcggt acttcatcag gcaatggtaa
    54541 aacatctgga cgcggtcaaa aaggtcaaaa ggctcgtagt ggtggtggcg tacgtctagg
    54601 ctttgaaggt ggacaaacac ccttgttccg tcgtattcca aagcgtggat ttacaaatat
    54661 caacactaaa gagtatgctc ttgttaacct tgatcaatta aacgcttttg aagatggcac
    54721 agaagtaact ccagttgttc ttaaggaagc tggaatcgtt cgtgctgaaa agtcaggcgt
    54781 taaaattctt ggtaacggcg aattgactaa aaaattgact gttaaagcag cgaaattttc
    54841 aaaatctgct gaagcagcca ttactgctaa gggtggttca atagaagtca tctaatgagg
    54901 ggatactcat tatgttctta aaaatactca aagacgcatt gaagataaag aatgttagaa
    54961 ataaaatatt ttttacaatc tttattatcc ttatattccg tattggaaca catatcactg
    55021 ttcctggtgt aaatgcaaaa agcttagagc agctgagtga gcttcccttc ctaaatatgt
    55081 tgaacttggt cagcggtaat gcaatgagaa acttttcagt tttctcaatg ggtgttagtc
    55141 cctatattac agcctcaatc gttgttcagc tattgcagat ggatattttg ccgaagtttg
    55201 ttgagtgggg aaaacaaggt gaggttggcc gtcgtaagct aaaccaagcg acgcgctata
    55261 tttcccttgt cttagccttt gctcaatcta tcggtattac agcgggtttt aacaccttat
    55321 caagtgtggc cctagtcaaa acaccagatg taagaaccta tttactgatt ggagctttac
    55381 tgacaacagg tagtgtgatt gtgacctggc ttggtgaaca gattaccgat aaaggctttg
    55441 gtaatggggt gtctatgatt atctttgcag gtatcatttc ctctattcca aatgctattg
    55501 caaccattcg tgaggattat tttgtcaatg tgaagtcagg tgacctacag tcatcttata
    55561 tcgttgttgg tattctcatt cttgcagtgc ttgctatcgt ctttttcaca acgtatgttc
    55621 agcaggcgga atataaaatt ccaatccaat atacaaagct tgttcagggt gcgcctacaa
    55681 gctcatacct tcccttaaaa gtaaatccag ctggtgttat tcccgttatc tttgccagct
    55741 cgattacaac aattccaagt acgattatcc cgttctttca aaatggcaga gatattccat
    55801 ggttgacaac tttgcaagga atttttaact atcaatctcc aacaggaatg attgtttatg
    55861 ccttgttaat tatcctgttt tcattcttct atacctttgt tcaagtaaat cctgagaaaa
    55921 cagctgaaaa tctacagaag aattcgtcct atattccaag tgttagacct ggacgagaaa
    55981 cagaagaatt tatgtcatcc ttgctaaaga aattggcaac tgtgggtgct atcttcctag
    56041 catttatatc tcttgttcca attgcggcac aacaagctct taacctatct tctagtattg
    56101 cattaggtgg aactagcttg ctgattttga tttcgacagg tatcgaaggt atgaagcagc
    56161 ttgaaggtta ccttctcaag agaaaatatg tcggatttat gaatattaca gaatagaata
    56221 tgggttgaca ctgtcaacct tctattttgt ttttaaatga caataagatt tacagagcct
    56281 tggttcctat cttcttattg ccatttgaaa acaaaaacaa ggaaaactaa atttcctatt
    56341 atctttatgt caaaagagga gaaaaagatg aatcttttaa tcatgggctt acctggtgcc
    56401 ggtaagggta cacaggctgc aaagattgtt gaaacctttg agcttattca tatttcaaca
    56461 ggagatatgt tccgcgctgc aatggctaat cagactgaaa tgggagttct tgcgaaatct
    56521 tatatcgata agggtgattt ggtgccagat gaggtaacca atggtatcgt taaagaacgc
    56581 ttagcacaag ctgatattaa agaaaaggga tttcttttag atggctatcc tcgtaccatt
    56641 gagcaggcac atgccttaga tgaaacctta aaagcattgg gacttacgtt agatggtgtg
    56701 atcaacattg aggttgaccc tgcgtcactc attgacaggc ttagcggtcg tatcatcaac
    56761 aaaaaaacag gggaaacctt ccataagatc tttaacccac cagtgggaga ctataaggaa
    56821 gaggactttt atcaacgtga agatgataag cctgaaacag ttaagcgtcg cttagatgtt
    56881 aatattgcac aaggtgagcc tattatcaag cattatcgtc aagcaggcat tgttcgtgac
    56941 attgacggaa acaaggacat ttctgaggtc tttgctgaca taaaaaaggt catcgaaaac
    57001 ctgaaataaa ttccagaaaa tcgcttgcga aagtgatttt atcgtgatat actagactag
    57061 tctgacttat aattgttacc tctgtgctca gaggacatca aatcgaaatt tagggggtac
    57121 ttttgcgtgg caaaagaaga cgtgattgaa attgaaggta aagttgtcga aactatgcca
    57181 aatgcaatgt ttactgttga attggaaaat ggacatcaga ttttagcaac cgtatcagga
    57241 aagatccgca aaaattacat tcgtatttta gtgggtgatc gtgttactgt agagatgagt
    57301 ccttacgact tgacacgtgg acgtatcaca taccgcttta aatagtcgaa ataattggag
    57361 ggattaaaac atgaaggtaa gaccatcggt taaaccaatt tgcgaatact gcaaggttat
    57421 tcgtcgtaac ggtcgtgtta tggtaatttg tccgacaaat ccaaaacaca agcaacgtca
    57481 aggataagat agaaaggaga aaaaatggct cgtattgctg gagttgatat tccaaatgat
    57541 aagcgtgtag taatttcact tacctatgtg tatggaattg gtcttgcaac atctaaaaaa
    57601 atcttagcag cagcaggtgt ctctgaggac attcgtgtta aagatttgac atcagatcaa
    57661 gaagacgcta tccgtcgcga agtggataca attaaagttg aaggtgatct tcgtcgtgaa
    57721 gtaaacctaa atatcaagcg tttgatggaa atcggttcat atcgtggaat tcgtcaccgt
    57781 cgtggacttc ctgtacgtgg acaaaacaca aaaaacaatg ctcgtactcg taaaggtaaa
    57841 gctgttgcga ttgcaggtaa gaaaaaataa aataggaggt aaaaaaattg gctaaaccaa
    57901 cacgtaagcg tcgtgtgaaa aagaacatcg aatctggtgt tgcacatatt cacgctacat
    57961 ttaataacac tattgttatg attacagatg tgcacggtaa tgctttagca tggtcatcag
    58021 ccggtgctct tggttttaag ggttctcgta agtcaactcc ttttgctgct caaatggctg
    58081 cagaggctgc tgcgaaatct gcacaagaac atggtttaaa aactgttgaa gttactgtaa
    58141 aaggtcctgg ttcaggtcgt gaatcagcta ttcgtgccct agctgctgcc ggtcttgaag
    58201 taactgccat tcgtgatgtg actcctgtac cgcataatgg tgctcgtcct ccaaaacgtc
    58261 gtcgtgtata atcacagtaa caaatagtac acaagtttcg tttcgagggg tgaaagaatg
    58321 attgagtttg aaaaaccaat aataacaaaa attgatgaaa ataaagatta cggtagattt
    58381 gtaatcgaac cacttgaacg tggatatggt acaactctag gtaattcact tcgtcgtgta
    58441 ctcttgtctt cacttccagg tgcagctgtt acatcaatca gaattgatgg agtactacac
    58501 gaatttgata caatcccagg tgtacgtgaa gatgtcatgc aaattatcct taatgttaag
    58561 ggacttgctg tgaaatcata cgtcgaagac gaaaagatta tcgagcttga tgtagaaggt
    58621 ccagcagagg taacagctgg agatattctc acagatagcg atatcgaact tgttaaccct
    58681 gatcattatc tttttactat tgctgatggt tatacattga aggcttcaat gactgtcgct
    58741 aaaaaacgcg gctatgtacc agcagagggt aataaaaaag atgatgcacc tgtggggacg
    58801 ttggcagtag attcaatcta tacgccagta aaaaaggtta attatcaagt tgagcctgct
    58861 cgtgtaggta gtaatgacgg ctttgataaa ttgactattg aaatcatgac aaacggaaca
    58921 attattcccg aagatgcctt aggtttatct gctcgagttt taatcgaaca cttgaattta
    58981 tttactgatt taacagatgt tgcaaaggca actgaagtga tgaaggaagc tgaaaaagtg
    59041 aacgatgaaa aggtacttga tcgcactatt gaggaacttg atttgtccgt acgctcatat
    59101 aactgcttga aacgtgccgg tattaatact gtcttcgatt taacagaaaa atctgagcct
    59161 gaaatgatga aggtccgtaa ccttggacgt aagagtcttg aggaagtaaa ggtcaagctt
    59221 gctgacttag gtttgggact aaaaaacgat aaataacata ggaggataaa atggcttacc
    59281 gtaaactagg acgcactagc tcacaacgta aagcaatgct tcgtgactta acgacagatc
    59341 ttttgattaa cgaatcaatt gtaacgacag aagcacgtgc aaaggaaatc cgtaaaacag
    59401 ttgaaaaaat gattactctt ggtaaacgtg gtgatcttca tgctcgtcgc caagcagctg
    59461 catacgttcg taacgaaatc gcatcagaaa actatgatga agctactgat aaatacacat
    59521 caacaacagc tcttcaaaaa cttttctctg aaattgcgcc tcgttatgca gaacgcaacg
    59581 gtggatacac tcgtatcctt aaaacagaac cacgccgcgg agatgctgct ccaatggcga
    59641 ttattgaatt agtttaattt ttatcaattt tgttgagtgt tatgatgatg gagcagttcc
    59701 tttaagctgt tcttagtcta gctctggtct accgctagga cctttcctag cggtaacact
    59761 caccatgttg agaataagta acgcttgttt acgaaaggtc tctaagctgt aggtgccctt
    59821 cgtaagcagg cgttttgttg tgactccatg ttaactgtag tagatgacta atatctaata
    59881 tctagagagg atcagcttgg tgctctcttt tctgatatta aaagcattgg gaatcttggt
    59941 tttgaagttc ttaaagctcc taaagccaaa gtctttcgct tgatgtcttt ggtcatcttg
    60001 ttagtggtct ccggcttagc attggaataa ggtagttcaa agcattggtg atgtaagatc
    60061 tatacttcct gaaggtcttg aaaaccgttt tgaaggtgtg attgacctgt agcgggagta
    60121 gattagatca atggcgtttg gctgctttga aaatttaggt gacaattgtt tttgtatctt
    60181 tgtttaaaaa tggtataata ttaaaacatt aaacaaaatg tacataaaaa agccatataa
    60241 aagaatgata ttaagataat gtgatcaata gttttagaaa atgaatgtgt aaggttaagg
    60301 tatgccccct tgatataatg ctagttttac gaagaggcat tctgtacaga cataatgcac
    60361 tcttacaaat gatacggtaa ttgctcaaca aggcgcaaca gccttggcaa atgtaatatt
    60421 tgccttagct agcagcgaat tagttacgct tgatacatag acaagggttt ctggcataca
    60481 gcagcagatg gtgtgcctgt ctcagagagt ggctgcttgg cttatcctat tcatgtttta
    60541 aaacttacag gaggtgttat gtggcctttg gtcgatggat atttagctag gtgaacagct
    60601 attagctgta aatatgaggt aggagcttta gtttgcatga tgttaaatga attgaaacag
    60661 acttaggaaa gcttggctta gcaactatca cgcaagttct taacaacgat aaagatcgta
    60721 tgggaaaata tgatcaagca tcaacggaca tgagatgtgt tttatgaaga aaccattata
    60781 cttttataag acttatttag ttgtttttct ttgcggactt gtttgaggag tagtctacat
    60841 aggcaatagg ctcaggctta cagcacttag gagacattag agcatgagaa gcactaactg
    60901 gctagtgata gaaaagtaat agcacagtgt ttttataact aacaagagga gtagacattc
    60961 tatgagtatt gacatgtatt tgagcttatc tgaagagcag gcacagagtg tagaggctgt
    61021 cttagctagg cgacaaacag cctatcaatc cttacaggag accttgatcc aattgatttc
    61081 taacagtcct gatttatcag ggcggaccta tgattctgct aaggcttata gtagtcaagt
    61141 gctaattcct ttgttaaagg ggtgtatgct tttagatgag gcgattataa cagcctgtaa
    61201 gaggctacct agtgagtacc gtagtcaggt agaccaaatt gatttgaagg agagtgatct
    61261 ggttgagcgt attgcccagt tcgatcatgt gattggtcgg tacatggatt tgattagtat
    61321 tgaatacagt agagaggagc ctagctattc ttatatctct catttaagat cagctgagca
    61381 gctccatcgg gccgttaagc ggcgtcttga ggagatattg cgaaggctaa ggcattttga
    61441 taccaactca gttcaccttt tttcgactat tcagactttg gcagcagcgg tacaaatagg
    61501 catgcgtcaa gctaggacct cgtggcatgc aggaagtcag gtatttgtga tttcagagga
    61561 tatggcatgg gccgatacga ttaattctaa gtggtcaaaa agtaaagggt taagctatct
    61621 tagtgattat gtttacgacc cagatgtgct ctctaagaga gcagctatta atcactcttg
    61681 gattaaaaca ggctatacta tgtctaaaaa ttttggcaaa gctgtttcaa aagattatac
    61741 aaaagcaagc tttttgagct atggtaaggc agccaaggcg actggctgga cttctatggc
    61801 agtagatact ggaataacta gtgtaaggga atacaataag aaaaatagta gagcctatgg
    61861 cagtgagggc aaggcgctta ttcatgctag tgtggctcaa atcaagagca tgggacctat
    61921 agaaggggcg ataattggca gtaaagctgg accttgggga gcattaatgg ggtttgttac
    61981 aggaggcatt aatgttactt ggggagtagt gcatccagag tctaaggaca acatgttttt
    62041 atggatacaa gataaaatgg atgatgttta cgattcgatt gttcagacag atcttggcaa
    62101 agggacgcac catgctaaag aaagtgtcaa aggtcatatc ggtcgagcta ttgtaaggac
    62161 atgggacttt gtcagtcaat catttggtaa aggagtgggc tatgacattt aaagatcagc
    62221 tttttagtgg gacgtttgag caatcaaaaa agattgtgtc taaaagtata ttgacagaag
    62281 aaggtgcgca gattggagta ttctcatcta tgagtctatg gaagagaata acaggcttga
    62341 tgatgttgcc attatttgct atttcatatg gagtaggagt tgtgttacct gaacactttc
    62401 aacaatcaac agaaggagtt caagctattt cattggctgc aatagagatt attgccagat
    62461 taggacagtt cagtcgatac tttatcattt gttttatttg tatgtctgtt ggattaatta
    62521 ttagtaatat ccttccaaag cctaactagg cttatcaatt attatatggc aatgctactc
    62581 ttattatact tagtattaca actattatct cagccttccc tttaactgct ggccttacaa
    62641 ttgcagcttt tggctggatc ggttttttgc ttcagctatt gctttgcctt tatttgtgga
    62701 aggtttgtgt catagataag tgtcaacagc tacgcacagc aatttatcaa gaaagcacca
    62761 tagcacctga ttggggcagt aagctagtaa gctttattaa gtcttatggt ggtatcttat
    62821 taggcctctc tgttctcaac cgctggactc tcaatctagg agagctagtc aaggaaagcc
    62881 ctggtttgtt gagttttctg tacggctgga tttttctatt gttcatgttt ttgatgctat
    62941 ttgcactggg tcaagcgtta aaaaatacca tcatagccta ttattttttt agatatcaaa
    63001 aagaataccg caagcatttt aatataagcg atgagcagtg gtacggtaaa tggcgtttaa
    63061 aaatattatt aaaataaacg atataaggag taatcatatg caaaaagaat tattaccgtt
    63121 aggaagtgtt gtctatctag agggagcaac aagcaagcta atgattgtcg gacgtggtcc
    63181 tatatttgaa tctaatggcc aaaatgtcta cagtgattat gttggagtaa tgtatccaga
    63241 agggatcaat ccagaagacg cgattttttt caaccatgaa gatattgcaa aaacagtctt
    63301 tgaaggcttc aaggacgaag aagaacaacg ctttttagaa gtgtattctg attgggagag
    63361 tactttagaa atttccaaaa taaagctata gatgaactgt agcagatata tttgtcagta
    63421 gattgtcatg attatattga aagattatga ctttctctgg cttaaatacc tctaaagttc
    63481 caaagtttag aaaaggcttt aaaatgagtg ttataatagc atttatgctc attaaataaa
    63541 ggtagcattt caatagaatc ggtaaaaaaa
//
LOCUS       DARYJX010000006        62860 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYJX010000006 DARYJX010000000
VERSION     DARYJX010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62860
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(93..869)
                     /locus_tag="TU257_000358"
                     /pseudo
     CDS             complement(93..869)
                     /locus_tag="TU257_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            complement(965..2512)
                     /locus_tag="TU257_000359"
     CDS             complement(965..2512)
                     /locus_tag="TU257_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0833404.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            complement(2487..2726)
                     /locus_tag="TU257_000360"
     CDS             complement(2487..2726)
                     /locus_tag="TU257_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0833405.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            complement(2739..4862)
                     /locus_tag="TU257_000361"
     CDS             complement(2739..4862)
                     /locus_tag="TU257_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0833406.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            complement(4866..7295)
                     /locus_tag="TU257_000362"
     CDS             complement(4866..7295)
                     /locus_tag="TU257_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0833407.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(7207..7596)
                     /locus_tag="TU257_000363"
     CDS             complement(7207..7596)
                     /locus_tag="TU257_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0833408.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            complement(7600..7863)
                     /locus_tag="TU257_000364"
     CDS             complement(7600..7863)
                     /locus_tag="TU257_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0833409.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            complement(7883..8749)
                     /locus_tag="TU257_000365"
                     /pseudo
     CDS             complement(7883..8749)
                     /locus_tag="TU257_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8769..8984)
                     /locus_tag="TU257_000366"
     CDS             complement(8769..8984)
                     /locus_tag="TU257_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0833410.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            complement(8988..9299)
                     /locus_tag="TU257_000367"
     CDS             complement(8988..9299)
                     /locus_tag="TU257_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0833411.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(9463..11244)
                     /locus_tag="TU257_000368"
                     /pseudo
     CDS             complement(9463..11244)
                     /locus_tag="TU257_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(11241..11726)
                     /locus_tag="TU257_000369"
     CDS             complement(11241..11726)
                     /locus_tag="TU257_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL0833412.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            complement(11723..12497)
                     /locus_tag="TU257_000370"
                     /pseudo
     CDS             complement(11723..12497)
                     /locus_tag="TU257_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(12494..13273)
                     /locus_tag="TU257_000371"
     CDS             complement(12494..13273)
                     /locus_tag="TU257_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL0833413.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            complement(13360..13641)
                     /locus_tag="TU257_000372"
     CDS             complement(13360..13641)
                     /locus_tag="TU257_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833414.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TU257_000373"
     CDS             complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TU257_000373"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0833415.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(15370..16800)
                     /locus_tag="TU257_000374"
     CDS             complement(15370..16800)
                     /locus_tag="TU257_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0833416.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(16999..17493)
                     /locus_tag="TU257_000375"
     CDS             complement(16999..17493)
                     /locus_tag="TU257_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0833417.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TU257_000376"
     CDS             complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TU257_000376"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL0833418.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(18902..19840)
                     /locus_tag="TU257_000377"
     CDS             complement(18902..19840)
                     /locus_tag="TU257_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL0833419.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(19842..20702)
                     /locus_tag="TU257_000378"
     CDS             complement(19842..20702)
                     /locus_tag="TU257_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL0833420.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(20719..22002)
                     /locus_tag="TU257_000379"
     CDS             complement(20719..22002)
                     /locus_tag="TU257_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0833421.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(21995..22549)
                     /locus_tag="TU257_000380"
     CDS             complement(21995..22549)
                     /locus_tag="TU257_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833422.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(22843..24132)
                     /locus_tag="TU257_000381"
     CDS             complement(22843..24132)
                     /locus_tag="TU257_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0833423.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
     gene            complement(24693..26483)
                     /locus_tag="TU257_000382"
     CDS             complement(24693..26483)
                     /locus_tag="TU257_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL0833424.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
     gene            complement(26598..27401)
                     /locus_tag="TU257_000383"
     CDS             complement(26598..27401)
                     /locus_tag="TU257_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0833425.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            complement(27665..28504)
                     /locus_tag="TU257_000384"
     CDS             complement(27665..28504)
                     /locus_tag="TU257_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0833426.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(28520..29614)
                     /locus_tag="TU257_000385"
     CDS             complement(28520..29614)
                     /locus_tag="TU257_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL0833427.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            complement(29876..31273)
                     /gene="uxaC"
                     /locus_tag="TU257_000386"
     CDS             complement(29876..31273)
                     /gene="uxaC"
                     /locus_tag="TU257_000386"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL0833428.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            complement(31301..31918)
                     /gene="eda"
                     /locus_tag="TU257_000387"
     CDS             complement(31301..31918)
                     /gene="eda"
                     /locus_tag="TU257_000387"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0833429.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            complement(32101..32772)
                     /locus_tag="TU257_000388"
     CDS             complement(32101..32772)
                     /locus_tag="TU257_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL0833430.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            complement(32814..34604)
                     /gene="uidA"
                     /locus_tag="TU257_000389"
     CDS             complement(32814..34604)
                     /gene="uidA"
                     /locus_tag="TU257_000389"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL0833431.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            complement(34625..35653)
                     /locus_tag="TU257_000390"
     CDS             complement(34625..35653)
                     /locus_tag="TU257_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0833432.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            complement(35737..37281)
                     /locus_tag="TU257_000391"
     CDS             complement(35737..37281)
                     /locus_tag="TU257_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0833433.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(37696..38955)
                     /locus_tag="TU257_000392"
     CDS             complement(37696..38955)
                     /locus_tag="TU257_000392"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0833434.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(39271..40476)
                     /locus_tag="TU257_000393"
     CDS             complement(39271..40476)
                     /locus_tag="TU257_000393"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL0833435.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(40809..43028)
                     /locus_tag="TU257_000394"
     CDS             complement(40809..43028)
                     /locus_tag="TU257_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0833436.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            43555..44496
                     /locus_tag="TU257_000395"
     CDS             43555..44496
                     /locus_tag="TU257_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL0833437.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(44471..44674)
                     /locus_tag="TU257_000396"
     CDS             complement(44471..44674)
                     /locus_tag="TU257_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL0833438.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(45055..46731)
                     /gene="dnaX"
                     /locus_tag="TU257_000397"
     CDS             complement(45055..46731)
                     /gene="dnaX"
                     /locus_tag="TU257_000397"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL0833439.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(46731..47228)
                     /locus_tag="TU257_000398"
     CDS             complement(46731..47228)
                     /locus_tag="TU257_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL0833440.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            47408..48178
                     /locus_tag="TU257_000399"
     CDS             47408..48178
                     /locus_tag="TU257_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL0833441.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(48360..48632)
                     /locus_tag="TU257_000400"
     CDS             complement(48360..48632)
                     /locus_tag="TU257_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL0833442.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(48655..49281)
                     /gene="udk"
                     /locus_tag="TU257_000401"
     CDS             complement(48655..49281)
                     /gene="udk"
                     /locus_tag="TU257_000401"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL0833443.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            49377..50471
                     /locus_tag="TU257_000402"
     CDS             49377..50471
                     /locus_tag="TU257_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0833444.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(50736..52022)
                     /locus_tag="TU257_000403"
     CDS             complement(50736..52022)
                     /locus_tag="TU257_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0833445.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            52444..53607
                     /locus_tag="TU257_000404"
     CDS             52444..53607
                     /locus_tag="TU257_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0833446.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(53730..56348)
                     /gene="alaS"
                     /locus_tag="TU257_000405"
     CDS             complement(53730..56348)
                     /gene="alaS"
                     /locus_tag="TU257_000405"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL0833447.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(56704..57705)
                     /gene="prsA"
                     /locus_tag="TU257_000406"
     CDS             complement(56704..57705)
                     /gene="prsA"
                     /locus_tag="TU257_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL0833448.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(57768..58475)
                     /locus_tag="TU257_000407"
     CDS             complement(57768..58475)
                     /locus_tag="TU257_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL0833449.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(58558..59196)
                     /locus_tag="TU257_000408"
     CDS             complement(58558..59196)
                     /locus_tag="TU257_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0833450.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(59246..59878)
                     /locus_tag="TU257_000409"
     CDS             complement(59246..59878)
                     /locus_tag="TU257_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0833451.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(59868..60425)
                     /locus_tag="TU257_000410"
     CDS             complement(59868..60425)
                     /locus_tag="TU257_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833452.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(60624..62426)
                     /gene="pepF"
                     /locus_tag="TU257_000411"
     CDS             complement(60624..62426)
                     /gene="pepF"
                     /locus_tag="TU257_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0833453.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(62416..>62860)
                     /locus_tag="TU257_000412"
     CDS             complement(62416..>62860)
                     /locus_tag="TU257_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0833454.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT        17776 a        14650 c        11230 g        19204 t
ORIGIN      
        1 gcattaaagc aaagctaaaa ggacttagcc ctgtgcaata cagaactaaa tcctttcaat
       61 aattattcgt ccaacttttt gggggcagta catttagtaa tcttttcttt ttgaatgaca
      121 tcagttattt caatcttatt gcccactaaa gttaagagct gctctgctgc tatttcatca
      181 tcaattctat ctgttgaaag tgtaaagcta tttgtagaaa gctctaccgt ataatatttt
      241 tctttcttaa agtttgctat ctcatcatct ctttttacga tcatagcaag agtcggtgtt
      301 tgtactctgc caacactgta attttgctta tacagacaag aatagagcct gctgatattc
      361 attccgacaa gccagtcagc gatagctctt gcctgtgccg actcaaagag attatcgtaa
      421 tcttttccgt cttttagatg atcaaagcca tctttaatgg cagtatcttc catagatgaa
      481 atccaaaggt gtttcatctt ctttttacaa ttcacttgat tatatacaag tctaaaaatg
      541 ctctcccctt ctctacctgc atcgcacgca ttgataaccg tatcaatttc tttgtcgttc
      601 atcaactttt taaggatgtt aaattgtttc ttggttgact ttgccacttc atacttatag
      661 tccttgggga taatcggtaa atcaaccata ttccacttgg catacttttc atcataaaca
      721 tccggatttg ccatttgaat taagtgtcca acacaccaag atactttgta tccatttccc
      781 tcataatatc cgtctttctt tttatttgct ccaagtactt ttgcaatact taatgctaca
      841 cttggttttt ctgcaatgac taacttcatt tctgtactgc ctcctgtttt caatataaaa
      901 gggcgaaaga ttttattctc ccgccctgca tttgcaccaa atactgtatt tttttggtgc
      961 agcattactg ctcatcttcc gcttctactt catctacatc atttgtttct tcctcgcttt
     1021 cagcttcaga aaagaaatca tcatcttctt cctctaatgc ttcaagctcc ttatcttctt
     1081 tcttttttac aaccttaaag tagtatcctg ctcccaatgc tccgcctaca acaagaagca
     1141 gaataatata tgttcctaaa ttactctttt cttctttttt ctcaggcttt acttcttcct
     1201 taacaggttc ttcttttaca atctcctgct ttggagcttc ttttttctct accatgttaa
     1261 gcaaatcatc ttcggatact tctgtaagaa gcatgacatt ctcactatcc tcatcgtggt
     1321 tgatgatgag atgaaaggtc ttaccgtttt tagtttgaaa ggtaataaac tgtcttgcat
     1381 cagcggaata ttgatccgtt tctttattat cgctgctatc cccatgatga atcggataat
     1441 ctttatttcc attatcttta ttttctgtaa cagttcctct tgcctttgac ggagatgaag
     1501 ctactccctt attggtattt acattactac ttgccccctc cattgacgaa tcttgactgc
     1561 tgttattagc aggtgctttt gctgtcaatt tattagaata gcgaacttcc ttttctttct
     1621 cctttacttc tgttttgctt gtatcctttg tagcattccc tgaactcacc gtatcagatg
     1681 agcctttacc ggaactactt acagaagtct gtggtgtttg gggagaaatg cttgagcttg
     1741 tcttaattcc ggaaatagga ctaatcggtg taacagaatt tattgcttca gaagatttct
     1801 ttgtttcagt tgcctttttc tcaagctctt tcaccttatc agtcagctta tctatttcct
     1861 ttttcatatc ttctgataag tccttatttc ctttatcttt cttcattttc tctttcaggc
     1921 tgtcaatttc atcttcaagg tctttgattt tttctttctg cttatccttg tctttaagct
     1981 caccatttaa cttatcaaat ttttcttgaa gctctttagc ctctttttcc atcttagaaa
     2041 tatcgtcttt agaaagctct gtctgtgtgc ctttatcctc cgtttttgta gcttctgttt
     2101 gcgtgctttc gtcctgcttt ggtttttctt cttccgtttg cgtttcctta tccttaacct
     2161 cagtctttgc taccttacgg ataatttcat catttccatc tccctttact tcataaaaca
     2221 ggaattcatc aataaatttc atatcatcag ggagcattgg aagatcgcca ctatcaagaa
     2281 gctgtccttt ctctgcctta atcttttctt ccttaaatac cttttcatct tcaaagatat
     2341 actttacatt tacttcaact tccgtttgga cagcttcgtt ttttgtagga gcgtcagagc
     2401 ttttctcctt ggcgtaaaca accgtccaaa gtcctaaaat gcagctaata cttacaatta
     2461 ctgcaagtgc tgctgtccaa aacttattat tctttttcaa actggttttc atttgtcctc
     2521 tcctttttca gttctgcttt ttctctgttt acctttgtca ttaaatcaga aattgtgatg
     2581 ttgttctttc tgcaaatcat gatgatttct tcattttcaa gttcttcttc acgaataaat
     2641 aaaggctcca attcttcatc aatcagagcc tttttatcct ttaacttttt tattctgttt
     2701 tttactgctg tcagttcttt tttcatattg ttccctcctt atctgtttac atttggtgga
     2761 aaaccaaagc ctaccggatg gtgtttacaa aaagtcgcaa tccaatcatc taaagtagtt
     2821 actcttatat aaccgatatt atcaataacc ttgccgtctc cgatatagat tccgacatga
     2881 ccataggtaa gtcctgctgt gcttccgcta ctgctgcttt ctaccgctac aagcattcct
     2941 accttgagct ttgacctatc ggatgtaaag gtatagtttc gatacatatc attagcattt
     3001 cctccgatat atccaagtcc cgcattttgg taaacttgcg atacccacat ggcacaccag
     3061 cctgcacccg gagatggagt gatatatgca gcattaacaa tcttcttttg tacttccgaa
     3121 gatgcctcat actctttccc accacctaca ccgccattag cactgataag gtcagaattt
     3181 ctaaaggctt ctcccatatt tccttgagca aggaataagg cttcatagtg ctttaaatta
     3241 tcgggatagt ctttaaagac ccttcggata atgctgtcca tctctttttt atgaagcgtt
     3301 acaatgagct tcttatattc ataaggctct tcatggcttt cggtatattc attgccatct
     3361 tcatcggtat aggtttctgt aactgtcctg tatctgattt caatttcttc cctgtattca
     3421 aggtcataca tggactcaaa caattctttt aatatggttt ctacttccga tacactcttt
     3481 acctctccgc accttgatgt aatgtaggat aaaagctcat ggacattatg accgatatac
     3541 tctgtgttgt ttaagatata ctcatcatat ccgggataat tctcttctac atgatccact
     3601 tcactttgaa gctcactctc catagcagaa aacttctgat tgatttcact tagaacattt
     3661 ggctttgata aatagcttgt tgtaagaaca gagtttgtag agttcataaa gcctgtcatg
     3721 cctgttcctg caaagttaat cacaaaattt cctaagatga tgatacctac gaagataagc
     3781 attagtcctt tggcttttcg gataatcata tcctttgagc ttttcagtgt tccgataagt
     3841 ccctctttaa tccgatctct gagtcttgac ttattctcac gagaaatcgc tgcctttacc
     3901 tgatttttct tttgaaatct tttataggca cttgctcttt tatactcatc tgtctttttc
     3961 agttcctctt tggcatcacg aaactctaac ttggatttac gctttctgat tttatagtcc
     4021 ttatttgtaa gctcatatcc ttttttagct cttttcttat ctgagtatct ctttatacca
     4081 tgaatgagtt ttgaacttgc atcggctgtt ttttctcccg cttctacgcc tttattttca
     4141 tcacttccat gagaaaggta atctcttacg gtttcacttc ctttggcaag tcctgacagg
     4201 gcagatactt ttaccatatc tttcttcagc tttttctttt ggtcttttga aagactgcta
     4261 tgttcttttt cgcccgcaac atctttccct gcctttttat cttcaggctt attctctttt
     4321 ggtacatcgt ccttttttct tgtatagagg ctttcggaat agtttttcct tttatactta
     4381 ttcttttgag ccttatgatt tttagaggga ttttctaatg atttttcttt ttgaggtaga
     4441 ttatcctcta catcataggt tgattcaaag tagtcgctgt ccctaaaatc attatcgtat
     4501 ctgtctatga ttccatcatt atcaaggtct tgtcctaaag aatcatagat tttcccgttc
     4561 tttacctcag tatcatagtc agcctttcct gcttcattta cacttccctt atcagaagcc
     4621 ctatactttg catttctttt agaagtcccc tctatctgct cattttcaga tcttaccttg
     4681 cttatcttct catgaacctt gtcctgaaat ctatctttgt catggacaat ttttcctctg
     4741 taatcatcgt tatgctttag cttactttct tcaggtatag agcttgtttc agctttaagc
     4801 atctcccttt caaggcttgc cttatgcctt tctctaaaat cttttttcag cttcccatcc
     4861 ataagctacc tcacttcttc aggcttggta gtcatcttct gataaagaat tgtatctttc
     4921 ggaaacttat caaggaaagg cacaatggta tttccaaaga aaagtagtcc ctcgccctca
     4981 ttggagttcg taacatatct aagctgcgga agtgagattt taagtttcct tgcaagtatt
     5041 tccctatctc ccgaagcctg atttaacatt aagacaaagt ccgtattatc aaagatattt
     5101 tcaatttcct tactcataag taggtctttg acattttgcg tgataccagt cgggattcct
     5161 ccccattttc taaaacgctt ccaaatctct accgaatatg aagctgtctg ctcatctttt
     5221 aacagcaagt gaaactcatc tatatagtac cttgtagcct tgtttcctct gttttgcgat
     5281 accttattcc acacctgatc ctgtataaca agcataccta ttttctttaa ttgacttcca
     5341 agctccttaa tatcaaaaca aagtagcttc ttatttaagt ccacatttga cctgtgatta
     5401 aagacattaa gagaacctga aacataaatt tccatctctg ttgccagctt tttccctacc
     5461 ttttcttcct gcccttttaa catatcgtat aggtcttgaa gtataggcat attgtcataa
     5521 gtcggatttt caaagtacct ttcgtaaatc ttaggtaagc atctatctat aacggacttt
     5581 tcttccgctg taagtccact accaccaact acaagctcaa gcatagacat aatgaagttt
     5641 gccttgtctt taagaggtgc gtccccatca ccgtagttca tatttatatc aagtggattc
     5701 aggtaatctt ttgacttact gctgacctta atgacttctc cattaaactg tcttacaagg
     5761 tttccatact ctccctccgg atcacagata atcacatcat cgtccgttac taaaatcgca
     5821 tttgccatct ctcttttggc actaaaggac ttaccactac ccggagttcc taagattaga
     5881 ccgtttgggt tctttaattt ctttcgatcc gccataatca ggttatggct taaagcgttt
     5941 agtccatagt ataggctatt acttgaattg ataaaaagct cctctgttgt aaaaggcata
     6001 aagactgctg ttgatgatga ggttagccct ctatctattt caatcttgtt taccccaaga
     6061 ggcagcacgc tcactaagcc ttgttcctgc gtatggtcaa gtcttttcaa tttacagtta
     6121 tgcttgtttg caatggagct tatctgagct atggtgttat cgagcttttg cactgtcctt
     6181 gcaaaattca taaagacaat acttacaaca aacatacgct catctcttgt ctgtaaatct
     6241 tttaaaagac tttttacatc ttctccgtaa gtaattaaat cacttggaag aatgtccatg
     6301 tcatagcctg accttacagc tttcttgttt tcctcaattc gcatcttatc aatatcggtg
     6361 ttttttcgtt ttaccatctt gatggcttct gactggtcaa tcgccttaat atgaaaagat
     6421 atattgatgt tatcatcaat atccaaaaac tccgataaca tacggtctga aagctcactt
     6481 gcaaggattt gaaaatgact tgttgctccg ataaacttcc caaacttgaa atacctgctt
     6541 ggcataaagt taaattcatc aggcacgata tatgttttgg tactttcctt tttcttcagg
     6601 tctttgtagg aaaactcaaa ggtcttattc ggatttaata tatcgtgaag aatctttagc
     6661 ctttcctcta ctgtaagact ttcagctctt acccccatgc ttttgagatt agataatata
     6721 tctatatcca atctttcaag ttttgatgta gcctgttcta aattgtctgc ctctactgta
     6781 aaggttacat actttgattt tttcagtccg ttatttcctt ttacaatctg actttttagc
     6841 atctctctaa actcaagtcg tatatcgtca aatccgtccc ctttatccgg tatctgaatt
     6901 gccgatttca tttcttcgtt tcgtccaagc tgattgatgt aggaaaactc aatcgctatg
     6961 cttggatcaa aggaatttag aaagtttgca aactgattaa aaatcaaatc cctatcttca
     7021 tctaaagcaa gctgatagtt aatgtcctga aaggctatgc ttttactgaa gtgcttttca
     7081 tcgagctggc atatcccgct ttttaagagt ctaagatagg gaatggtatc ttctaccgta
     7141 tagcgttttt gctcttttct aaagataaga tcaagtagtc cgctcttttc tttgttagac
     7201 tttcccttac tttgctttaa gtcctttctc tcctttttta atgccttttt gttttcttct
     7261 aactttagtt gctgaatttt tcttttcttg ttcaaggtaa acctcctttc tcactctctt
     7321 tgccggctga taaaacttat gaaggtagat atgcttaaaa tatttctcaa aggtcagtcc
     7381 gtccttttca aaaagtgtga taaaaaagat tggaagtgtg gacacgataa ggaatatgaa
     7441 agctatatcg tttggtacta cctttctcat aaataaatag acaggtattc caacaagtcc
     7501 tgcaatggta aatcctatga gctgtctttt tgtaaggtta aaggctacct ttgtcttgac
     7561 cttctttaag tccttgggta ttggtacata cgccatagct tacctcccat cttctttacc
     7621 ctttgaaaac tcctcaaagt gttcatatac agagccgatt tcatcctgaa taattgcaag
     7681 ctgttcatct gtattcttgt tatatctttg ctgcattaag caaaaatcat tatggcagcg
     7741 accgatgtcc tgtgttcttt cttctaattc ggcagctttg ttatgaagcc tgattctatc
     7801 aattaccgcc ataatgcctg cgaccattac tactgctgta aatactgttt ttcttttatt
     7861 catactatct ttcctttctt ttttagtgtg catttaatac gcttttggcc agtgttccgc
     7921 tctttagcat cattaacccc agcaaaaccg cataaccaag tatcgtcatg gtacttgtgt
     7981 gtatatctgt tatttcaatc gtcttaacta atactgcgta aattccaaga caaaccatta
     8041 aaaagagtcc ttgtagtcca agtgcaaata atcctttgat gtaatttgtg ccaatttgcc
     8101 cccattcttt gtttcccatc gtggcaaatg gaatggctga aaccgatgaa taaacataaa
     8161 tctcaaacat ccttccgtaa accacaagca taatcactat ggaaattgcc tgtatggcaa
     8221 ctttaatgag cgaggtttca aagagaatca tgataagctc tccaagtccc ttttctttta
     8281 gggtatccat catcgccact atctgatctc cggaaacggt ggcagaggtg tttatcaccc
     8341 ctgccgcctt atttaccata tgctgtgcta catcaaagac cgccattgaa aattcaaaag
     8401 cgtgagatac caaccataca gcaattcaca tcttgatgat gtacttgaaa aattcaaatg
     8461 tatccgtatt atcatgtagg ttatttttct gtataaccat attgataagc tcgatacaaa
     8521 ggactgctgt gataattagt cccgctatgg gaataatgac cgaatcgtta atgcttttaa
     8581 taaaggtaaa tacatctcca ttccacccca taggagtttt tcctacatct gttgcaactg
     8641 caccaacctt gtcgttgatg tcaagaaaca tggactctaa gtttgcttgg ataccgccca
     8701 gtagaagctc cttaaagaat tcttctattt tgtcgaatat cccaaacatc taagctctcc
     8761 ttttcttctt atctgagtac atttgcaaga agtggaatca gcttaagtcc gataaggaca
     8821 atacctcctc ccgccatcaa ttgcttgatc ccttgacttt tggctcccgg attatcgtta
     8881 ccataacctt ccatcaggtt aatgacaccc catgctccaa gtcctgctcc tactgccata
     8941 accaaaatct ttaatacatt tactgcctgt gcgaaaaatt ccataattta ttcctcctca
     9001 ttttcttctt tcttttcaat cttgttgtat gacttcacta caaaattttt gtaagtcttt
     9061 ccctcttttt cacgcttctt aaagtagccg aatacatgaa tcaaatcgcc cttttcaaag
     9121 tcctttgctt tatccgcttt ttctccatag gctgcacaat tgatgtactc cttgccttta
     9181 ccgtacttct ttacaagcgt aaaatttaca acttctactt ctttaccctc tttttcaaaa
     9241 cttgagaaag taggttctgc cactaagttg gcgttgatgt taatcatttc ttgcttcatt
     9301 aaaaatttct ccttttcatt tcaataaaaa aagcgaccgg aagtattact tttccaatcg
     9361 ctatactcat actatttagt tttttactca gtgggacttc tgatccttat catcttgcct
     9421 ccttactttt gcataaaaaa gcagcaaatc tattttgtag acttactgca ttcttgtaat
     9481 aactgtttcc ctattcagtt ttgcttttcc tttccgtttc atgtagcttt ctatatcaaa
     9541 taaatttttc ttatcatagt cctcaagcag cttatagttc ttgtgctttg taatatcgta
     9601 cttatctgaa agaaaaggtc tgacacctct aagctgaaag atacattttc caccatccat
     9661 gaccgtaatc tcatcctgac tcatcagctc tttgcctgtt ttttgatagt taagtccaaa
     9721 gctcttttga tttgaccttg tttccgatgt gttgtaaagg tcgatagttt ctttaccaag
     9781 cgtttcggac agctctttta gtgttttttt cctttccacc taagaataag gtactatcac
     9841 agttacccac aatggtatca gcattatcct tatatattgc ctttagctga gattgtgcct
     9901 gtaagataat actcgctgaa atttctctac ttctaattgt ggctatgagc ttctcaaact
     9961 ttggaattaa gccgatattt gcaaactcat caagtaagca tcttacatga acaggaagtc
    10021 tgccaccata tacatcatcc gccttatcgc aaagtagatt aaataactgt gaatacataa
    10081 tagacactac aaagttaaag gtatcatctg tatcagagat aataacaaag agtgctgtct
    10141 ttctatctcc caatgtatca agctcaagtt cgtcttcact catcaaatct ctaagttcct
    10201 gaatatcaaa tggagcaagc cttgcaccac aagatataag aatagatttt gctgtctttc
    10261 ccgcagccaa tttatatttt ttatattgct tgaccgcaaa gtgcgtaggc tcctttttct
    10321 caagtgcttc aaagagtctg tctattggat tcatataggt ttcatcatct tctcttactt
    10381 ctgaagcgtc tatcatatca aggagcgttg caaagttctt ttcttctctt ggagcttcat
    10441 agaagatata tccgataagt gctgtgtagt agagtttttc cgctttgacc caaaaatctt
    10501 cacccgcttt ttctccctca ccttttgtat ttgcaatgat tgtctgcact aatttgagta
    10561 tatctttctc agaatggata taggcaaagg gattgtattt catgctcttt ttgaagttta
    10621 tggtatttag aatttttatc tcatatccat tgtcttcaag catcttgcca cattcaatga
    10681 ctatcgttcc tttcggatcg gttacgcaat agctactgtg catctgcata aggttcggtt
    10741 ttacataaaa tcttgtctta ccacttcctg atccaccgat tacaagtaca ttcttgttac
    10801 gagcatactt tggattagcc ggtctaccat tcatagttag gcgttctgtc tgggtaagca
    10861 agatattgtt ttgaaacttt tcatccatgt atggctcaat atctttctta tttccccatc
    10921 ttgctgagcc atactctttc ccctgtctaa actttttagc attttacctt tggtatagac
    10981 aataaattta attaaagcag ccattcctat gcccattaaa atatccgccg gatgaatact
    11041 tggaagaaaa ctcatcgtgt tgatctccaa tatcccttga aagattttat ctatgacatc
    11101 accaccggta tagcttctca catgatgggc aaagatgttt cctaaataga aaaatgcaag
    11161 atagggaatg ttttgcttta caaactttgt cttatcctgc accttaaata agcctttgat
    11221 gtcctttaat attttatcta tcataggctc tgctcctttt gtttattctt gattttatct
    11281 ttggaaacag agttcttagc catttcctta aacttctcaa tattcttgtg aatagattct
    11341 ttcctttccg ttttcttttc agactgtgct aatgcgtgct taaaggcttt atccatcact
    11401 ttcatatctt tggcttgaaa gaatacagag tattttcctg tttccttatc cttcatcact
    11461 gaaaacttaa caccataccg attaagttct tttttcagtt ccttaagctc cgcttcttca
    11521 acaggaattt cttcaagctg tccctttttt accatatctt ttagctttac ttcatttccg
    11581 ttagcattaa ccagcttttc aagtcctcca agtttttctg cttctttcat caatttcttt
    11641 aataagttca gaattaactt tcctgttact ttagcagctc ttacttccat attcagcgtt
    11701 tttcttgcta tttcttcatt gatcaagttc tctcacctcc attcagtaac ctatctttat
    11761 ttcgattcaa tttatctctt tgaataatct ttctaaaatc ctctttggat tgtgtcgtag
    11821 gaaaggttag tggtgaagat agtcggtttc tgctttaagt acctgttgtt gacaatgtta
    11881 tatacctgct ctttggcata gcttgtatct ctttctattc ccaagtcatc caagataaga
    11941 acggaagtat ttacaaggga ttcaatatat gcgttcttat caaaatcaaa tcctcccttt
    12001 tgcagctcat tgataagctg tgcaaaattt cttattttaa cgcctatttg atactgttca
    12061 ataaggctat ttgcaatgga gcaggcaaga taggtttttc cacttcctac tgagccgtaa
    12121 aatagcagtc cgatattttc ttttttcatc tgctcatagt cttttacaaa attctttgca
    12181 atgataagac tttgattttc ttctccctga taattttcaa aggtgtatga ccactgaata
    12241 atagagttaa agcagttctt ttttaatcgt tctatttcca tctgcttttc tctttctttt
    12301 tttcttgcct ctctatctct atcgcatttg caagaaatct taaatatcat cttgttatca
    12361 aagaactcca tcacttttct gtcttttctt tcatgacaaa ctttacaaaa ggcgtgtccg
    12421 tccttgatat attctttttc aggatcgtaa gaatactcta catcctctat cattactttt
    12481 tctaattctt ttatcatagg tgttctcctt tatcatattc ttcccatgtc gggatatttg
    12541 atgttttcac ttctttgccc cttccctgat ctttataaaa ccatgaaagg attgttgcct
    12601 tatggtcttt ataggtcttt ccggtgcttt taatatatgc agataatctc tcaatataat
    12661 tatcaagctg tgagttcatt atgatttgta agtctgatat atcttcagca gctaaaaaca
    12721 cattttgaaa tgttccaagc ccgttttcac taaaattata ttctctctta ctatacttac
    12781 tcttattatt ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt
    12841 tacttctgag gttaaaatct tttacttctg aagtaaaatt ttttaacttc tgtaagtcat
    12901 cttcttttac ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa
    12961 gtccaagccg tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg
    13021 tttttatggc agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat
    13081 agataaatac cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt
    13141 taagaagcat tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat
    13201 caaccaatat ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat
    13261 agtcaaagtc catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt
    13321 tttctctatc gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc
    13381 attgattcct ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact
    13441 taacaaaaat cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga
    13501 tcctattgca gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc
    13561 aagtataaat gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat
    13621 tatttttatt atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc
    13681 ttaacgcatc cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat
    13741 ctttttttga tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg
    13801 ctatatatag tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag
    13861 cataggtagc cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac
    13921 ttatatactt atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca
    13981 ttggaaacaa gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct
    14041 tgatgtcacg cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca
    14101 tcgctgcact ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga
    14161 taactgttgg ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag
    14221 cgacatagta ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg
    14281 ctgcttcgat cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga
    14341 tggttccaat gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat
    14401 caatagctgt ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag
    14461 cagaaataca gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc
    14521 ttgtaaacgc cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag
    14581 aagtaatcgc tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt
    14641 taggtcgtgt tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca
    14701 caagatgacg aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc
    14761 gcaaaaggtc gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat
    14821 cagaaatcgg cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat
    14881 tgacacgacg aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa
    14941 ttgtttcttt gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct
    15001 gcttttgctt aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg
    15061 tacgcagata ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct
    15121 ctaccttgcc aaagccactg tttttattga cctttaggac acgcatctga atgatctcac
    15181 ctggaagagc attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat
    15241 catggcttaa atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc
    15301 cttttctttt actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta
    15361 tagcatatct tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat
    15421 aaagagagcc tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat
    15481 cgtcacatgc tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac
    15541 aaatgggaag gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc
    15601 cgtaaagagc ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg
    15661 acgtacggtc cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag
    15721 ggtacgacca tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc
    15781 tttcattcgt aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc
    15841 aaatttggca tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt
    15901 ttcaaagtca accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg
    15961 acgcacaaat tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa
    16021 ttttaaatca taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc
    16081 cctcatgaag gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat
    16141 tgtatctgtt cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa
    16201 aatattagtg ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata
    16261 attggccttg ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc
    16321 aacaagcagc agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt
    16381 ttttttcctt ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg
    16441 atctgggtca tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt
    16501 gctacgtctt tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc
    16561 actcatatca taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc
    16621 cctagtataa tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt
    16681 tgactttaaa aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa
    16741 taaataaaaa tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat
    16801 gctcttccaa ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat
    16861 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
    16921 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
    16981 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
    17041 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
    17101 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
    17161 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
    17221 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
    17281 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
    17341 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
    17401 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
    17461 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
    17521 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
    17581 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
    17641 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
    17701 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
    17761 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
    17821 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
    17881 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
    17941 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
    18001 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
    18061 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
    18121 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
    18181 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
    18241 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
    18301 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
    18361 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
    18421 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
    18481 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
    18541 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
    18601 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
    18661 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
    18721 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
    18781 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
    18841 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
    18901 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
    18961 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
    19021 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
    19081 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
    19141 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
    19201 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
    19261 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
    19321 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
    19381 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
    19441 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
    19501 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
    19561 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
    19621 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
    19681 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
    19741 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
    19801 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
    19861 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
    19921 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
    19981 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
    20041 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
    20101 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
    20161 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
    20221 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
    20281 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
    20341 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
    20401 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
    20461 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
    20521 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
    20581 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
    20641 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
    20701 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
    20761 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
    20821 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
    20881 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
    20941 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
    21001 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
    21061 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
    21121 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
    21181 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
    21241 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
    21301 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
    21361 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
    21421 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
    21481 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
    21541 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
    21601 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
    21661 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
    21721 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
    21781 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
    21841 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
    21901 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
    21961 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
    22021 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
    22081 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
    22141 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
    22201 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
    22261 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
    22321 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
    22381 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
    22441 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
    22501 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
    22561 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
    22621 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
    22681 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
    22741 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
    22801 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
    22861 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
    22921 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
    22981 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
    23041 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
    23101 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
    23161 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
    23221 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
    23281 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
    23341 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
    23401 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
    23461 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
    23521 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
    23581 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
    23641 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
    23701 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
    23761 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
    23821 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
    23881 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
    23941 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
    24001 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
    24061 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
    24121 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaactat
    24181 taatgtcact tctattatac tacgccattc tttttaatca accattttat ttaatttttc
    24241 tgttaatttt tgtataatta attttattaa gctgtttttt gatgactatt aattgttaat
    24301 gctgacaaaa taagctatta ttattgattt tgttataaat cattaatata ttatattttt
    24361 tcataattta aaattattct taatatatca tctctaaaaa acattatctg ttcaattgtt
    24421 tcacttatca acaagcttat agcttgtcta tcatctgaag caaggttgag cattaggcac
    24481 aaaaagaaaa gctagaatga ccctctagct tttctttagg attaacaggc tctatcatct
    24541 ccatatcgga taaaactccc caccacaggg attatggggc tatttctgca gctacaaggg
    24601 gctgattaac aggttttatc ctgaaatctt tttaaatcat tcagagcaat caccgcagaa
    24661 cacgtaaagc ctctacttat cctgtagcaa cctcagaagc tatgccatag ctgggtatca
    24721 atcaagccac aaaaggcatc aacaggagac actccagtga attcagattc accagctaat
    24781 tttgcaacca aagccttcat agtgttgtcc ttgccatcgt aggcattaat ataagtacca
    24841 acctgtggca tatcagcaag ggcaaaggca tgctgaactg aaacaacgat tgttgggacc
    24901 tcatggacgt agaatggctg atccggtgtt cccttagcag ctggccagat aatacgctga
    24961 actgtacctc cagaattgac gtccaccaaa ttaagaatta aatcataatg ctctgtaatg
    25021 tttgaaatcg gctgcttttg tgcataaaca ttagcaatag ccgctgcacg ctcttcctct
    25081 ggtagctgca tgattcgctc ttcggttgat tcccagacag ttacctcatg cccacgcgcc
    25141 tctagcaatt ccttgacaat gtctgaggcc cgtttcttct gtcctgcaat catagcacca
    25201 aagccaccct tatagccctc cacgttaaca atcagcacac gcttgtagcg ctctggagtt
    25261 accgggaaaa tccctgcctg cttgtttttc acaagggtaa tggccttgtc ggcaacctca
    25321 tctgcaattg cttgagcctc tggtgtgtta atcaagacca tcgccttgtc cttaggcagc
    25381 ataatatctt ctcggtgtcc ttcaaagcga tgaagtccaa gctttgcttt caagccaagc
    25441 gtacgacgaa gggcgtcatg aaggcgttcg tcacttaaaa ttcctgcctc atagccctct
    25501 ttcatccatt gtaggtcttc atctgggtca ttaaagaata aaaagagatc gcagcctgcc
    25561 tcaatcgctg ttggtaacaa taagcgacgt ggcattgagg ctgtcatcgc aaccatatgc
    25621 gaagcgtcag tcacaatagc accattatag ccaagctcac cacgcagcag ctcatctaag
    25681 agggttttat taagtgaggc tggaagcata tcatctagct cacgctcagg gtgcatggcc
    25741 ttttcaacat ttggcaggtg aatatgtcct gccataatac caggtaagcc agcctctgca
    25801 agctcgccat aaatacgtcc aaagctagat agccactcct ccttggtcat tgggtttgag
    25861 gcaaaggaca aatgatggtc acgctcatca ataccatcac cagggaagtg cttggcaaag
    25921 ggcatgatac catattccat aatccccttc atatactctt tggaaagctc aatgatttga
    25981 tcaacattta ccccccagtt gcgattagca atgattggat tacgccaatt acgcgtcaaa
    26041 tcaacaattg gcgcaaagga ggcattacag ccaacagctg acgcttccag tcctgcaatc
    26101 cgtcccattt cataagcgta tttaggatcg tttgtcgcag ctaccttgat ttcatcacca
    26161 accttagtgc catcattgac agcaccatca ccaccagcct ctgtattggc agcaatgagc
    26221 attggaatct tggatttggt ttgtaaaata taattttgat cccaaatttc tgaagccatg
    26281 cctttattgt agcgaacagc tgcaatatga taatcctcaa gcacctgagt taaataatcc
    26341 tctgatcgac tagcccccat attaacaaat agctgaccta tcttctcctc caaggtcatt
    26401 gctgcaatgg tatcctccac ccagcaaata gcttcttcgt ctaggctata tggttttttt
    26461 cttaaatcta ctaaatgtgt cattgtactt cctttcaact aaagccttct ctgcttgctt
    26521 ttctgtttta atgaatggcg ctacagcaac ctgctaccaa gccctaacag gctcagctcc
    26581 actggtcagc tacctgccta cctatcaaga ttacgccaga aggcttctgt aaggctcttg
    26641 acatcaagct ctgtcaagtc accagttgta aaagcttcag cagcatgtga cagatcctgc
    26701 cacgagctag cctccttacc aacgaggatt ggaaaaaaag tgatctggtt ttgctcagca
    26761 gctgctagat cacctggtga atctcctatc atcatcatgc gctctctcac atatccttca
    26821 tcaatgagct gtgctatgac agcctctttt ttgccacgat cctgacaata caagccatca
    26881 acatgtgtca tcaggccttg atcctgccat tccttttgaa cggcctcttt attagctgag
    26941 ctgacaacaa aaacctggcc aagctggtgc aaggccttaa gagcagctaa agctcctaga
    27001 aatgccaatg cctctccttt gtaggcctca atctgacggt ttacctcatt tgaccagtcc
    27061 aaggcctttt gcaggtcatc actaggacgc ttaagaagct ccgcctccag agactgattg
    27121 gataatgagg cagtgtgttg tacccattgc tttaaagcgt caatccctgt aactcctgcg
    27181 tattctagcc ccataacaag cccaacaaag cggttaacac cgcgtgtacg cgaataaaga
    27241 ttaatgcgat cccactcttt taagaaagac gcttggtctg ctaccgcaaa ataatccgcc
    27301 gcaagcggac caaaaaagag ctgatgctta taagtcatgg tgtccattgc gcagccatct
    27361 gagtccacac aaaagacaaa ttgttcagtt ttagctgtca ttccaacctc caaatcatct
    27421 gatgaattaa ttctaacaca gtaagaaaac gctgtcaatc ataaatccta atcaagcagc
    27481 gtttcatttt taaaagctat cattacttgt tgattgctaa aaaaggctag agtgataagg
    27541 aacaatagaa gccacaaatc atcatacctt tattaatggc agcttggcta caaagcaagc
    27601 tgtcacgata gaaaaaccac ttgaggcatt gcagtttgag ttctcaagtg gtttattttt
    27661 tagcttagac gcctgaataa gctgcaaatc cgccatcaat tggcagaaca acgccgttca
    27721 caaaggaagc agactgctca tcagccaaga aaaagaggcc tccaattaat tcttctgcct
    27781 caccaaagcg tcccattggt gtattcttaa ggattttttc agcacgagcc gttggctgtc
    27841 cgtcctctgt gaaaaggagg ctacggtttt gattggttac caaaaatcca ggagcaatgg
    27901 cattacaacg aatgccaacc ttagaaaaat gaacagccaa ccactgggta aagttggaaa
    27961 tggctgcctt agccccagaa taggctggga tctttgttaa tggcgtaaag gcattcattg
    28021 aagaaatgtt aataatattt gcccccttac gaccaaccat atcctgagca aagacttgcg
    28081 tcggcaacaa ggtgcctaaa tagtttaaat taaagacaaa gctgatacct gcttcatcaa
    28141 ggtcaaagaa ggtttttgta tcctctggca ggcttgtgtc gtgaaactca ttatcggttg
    28201 ttgccttagg gctgtttccg ccagcgccat tcactaaaat atctgctgga ccaaaatctg
    28261 ctaaaactgc ctgacgaacg gcctctaggt tttctttaga caatacattt gcctgatagg
    28321 cctttgcaat accaccctct gcctcaatat catcaacaaa ggcctgtgcc gcctcttggt
    28381 taaggtctaa cagtgccacc ttagcccctg cttttgcaaa tgcctttgcc atactgccac
    28441 aaaggacacc gccagctcct gtgatcacaa caaccttgtc cttaaattca ataactcgac
    28501 tcatctcatg cccctttttc tatttatctc caactgtttt tacagtaatg ccaaaatctg
    28561 gtatctttcc agctgcacgc atattagcct cataaagccc attaaaatag gtcgcaccaa
    28621 gtgcccggtc atacagccca tagccagggg ttttggtttg atctccccag atacgacgac
    28681 catgatctgg acgaagtggt ccttgccagt cataatcaac caataatttg ataatagcat
    28741 tcatatcaat gtcaccagcc tgtgacaagt gagcggtttc ttggaagccc caatcaccag
    28801 cagtgacatt acgcgtatgc ataaagttaa tacgctggcg cttaagcgcg tactccgtca
    28861 tagcgatcac atcattttga ggatcagaag cataggagcc cacacacatg gtaatcccat
    28921 tattagggga atcataaagg tctaagaagc gctctacagc cttttgacct gttatgatac
    28981 gtggtaagcc aaaaatacca taaggaggat catcagggtg gatagccatc ttaacgccag
    29041 ctgcctctgc tgttggcata atagccttaa taaaataatc taaattagcc cacaggtctt
    29101 cttcggaaat atgatgacga taatgctcaa taatagcctt catctcttct tttgagtaag
    29161 aaaaatccca acccggtagg ttcaaatcat ctgccacagg atccacatct gccaagtctg
    29221 cctttaaaaa agcaagtgag gttgatccat caggcaatgg gtaattaaga tctgagcgag
    29281 tccaatcaaa cactggcata aaattatagc aaaccacagg aatacctgcc ttaccaacat
    29341 tgatgataga ggtcttataa ttttcaatca gctcatcacg attgggcttt ccttgcttga
    29401 tgtcctcgtg aacaggaatt gattcgatga ctgaaatctc aaggcctgca gcctcaacta
    29461 tcctcttcaa ttcaaggata ttttctagtg gccaagcctg accaactggt acatcataca
    29521 cagctgttac aattccctgc ataccaggaa tggccttgat ttcctctaaa cttactggat
    29581 catgctttcc ataccagcga aacgacattt tcatagtatc atacctcgag ttctcgtaaa
    29641 ctccttttcc tttcgattca cacaattgtt atttattatt gtttttgggg ctaataccct
    29701 tgcaactaaa gggcctgggc ctgctacttg gtctagcctt tgtaatctag tcaatcaaca
    29761 agacgccgac agcagctagc aggccgatat tgtcctagcc tcttttaaga ctaggacctt
    29821 aatcatagag caacatcata tttctatgct tcttctagtt aacgaccaag gcagcctagt
    29881 taaaatactg gatagcatta ttgtaggcaa tgtcctgagc cattttacca agtgcctgat
    29941 aatcctctgg tacctcacct tcttcaatcc actcaccaag gtaggtcgac aaaatacgtc
    30001 tgaaataatc atgacgctga taggataaaa atgaacgtga atccgttagc atgccgacaa
    30061 aattagctaa caaaccttgc tcagccaagg cattcatctg gctaatcata ccaagcttgg
    30121 tatcagcaaa ccaccagcct gcaccgaatt gcagatagcc cgcaataccg ttttcattgg
    30181 cttggaaatt agctagtgta ttagcaaccg cgatattata gctcggattt aggttatacc
    30241 aaatcatctt tggcaggctg tctctttgca ccagatgatc cagcaggcga ttcatattga
    30301 ttgctagtcc tgtttggtct cccagtgagt caacacccac atctgccccc agcttgttga
    30361 atatagctga atgattattg cgaagagcac caaaatgcac ctgagtaaca aagccatagt
    30421 gcttataaag cctgcaaagc tctgcaaaca ccgctgtctg ccattgcttg acctctaacg
    30481 gctgcggctg atagccctct aaaacccttg tcatgagacg gtctaattgc tctggctctg
    30541 ctgcttcaaa gacaatctct gtaaagctga tgtcactggc cttacaacca ttttctgcaa
    30601 aataggcaat acgctcttcc atagccgcta taaagctctt aaaatctgta atagttcttc
    30661 cggtagcttg agcaagacga gccacaaaat ctgcaaagcg ctgatgctca ataaaagcct
    30721 catctggtct aaaggttggc gcgacaaccg tctcaaaggt atcatcagca gctaacctct
    30781 tatgccaagc taggtcatca agcgggtgat ctgtcgtacc aataaaccgc actcggctat
    30841 ctgcaatcaa ctttctagga ctaatctggt gctcaaccaa gtaagcattg atacgatgat
    30901 agatttcctc tgcattatcc tcagtcagta gctcacagac accaaagaca tttttcaact
    30961 ccatcactga ccagtggtaa acaggattgc cataggagcg ctgaagtgta cgggcaaagg
    31021 ccttgaattt atccagctta gaggctgagc ctgtgatttc ttcttccgaa atgccattag
    31081 cgcgcatcaa gcgccacttg taatgatcac caccaagcca aaggtcaaca atattgtcat
    31141 aaaccttgtc ctcaaaaatt tcctttggat ctaagtgaca atggtaatca aaaataggct
    31201 gatccttgat ttgttgatag aggcgctttg ctgcctcatt ttttagcata aaattgtcgt
    31261 cattaaaagc catctcgtcc tcctcttatg accaattccc ttaatcaagg gctgatacaa
    31321 atgacgctgc aatacgggtt acactatcat agccctcagc ctcaactcgg ctagctaagg
    31381 ctgaaccaat cccaacagca acagcacctg catttttcca ctccttgaca ttgtcaatcg
    31441 acacaccacc tgatggcatc aaatcaacct caggaatagg accatgaata tccttaataa
    31501 agcctggtcc tacaacacct ccaggaaaga ccttaataat cggacaagag gcattcattg
    31561 ctgtgacaat ttcagtagct gttgcacagc ctgggaaata aagatttgat gcctgattgg
    31621 caacctctgc tatttctcta gaaaaatgag gactaactaa aaagctagca cctgctgcaa
    31681 tagcttctct tgccagatca ggcgtcatca ctgtcccagc tccaataatc acagcatcat
    31741 catgctcaaa ctcagctgac aatattctaa taacctctga agcatttgga gtagaatagg
    31801 taatctcgat attacgaata ccgcctaaaa tagcatgctt agcaatggca atagcgtctt
    31861 ctactgtttt tccacgaata atagcaaaaa aataattctc ttttaatcgg tttagcatag
    31921 gctcctcctt ttcatgaaac cgttgtctta gttttattat ataaatcatc agatgatttg
    31981 tcaaggaaaa agcaaaaaaa ggacttggtt ctagtatctc taaaaccaag ccctcttatt
    32041 cgagccaaga agcaaatcac tcaaaactca atagactgtt tccggcaagc aagcttaagc
    32101 ttatgataga aaagccgttc gcttaactgt catgatgtgc aggagcatag cgtcatgtgc
    32161 cgcgatcgga tctcccgctt taatcgcatt cagaatatct ctgtgggctt gtagagaatc
    32221 ttctttcatc tgacgatttg tgtaattggc attgatcaga tgaatcgact gattgatcac
    32281 cggtagcaag ctatccatag caatattgcc actgtatttt gccatcaagg aatggaaatt
    32341 cacatccagc tgcaaatgct taggatcacc agcagctacg gcctcttcaa tatcaacaac
    32401 aagcttctct aaggcttcaa cctcctttgg cgttgcatgc tgtgctgtca aagcggcaat
    32461 cctaggctca agcaatagcc gcaattcaaa caaatcagcg gtcagcttgg ctgtgtcctt
    32521 gactaaggaa aagcctaaag gatcctcaga aacacctttt ttcgagctaa tataagtacc
    32581 tgatccttgt ctaacctcta aaacatttct agttgctaag cttctaacag cttctctaat
    32641 agtgcttctt ccaacctcta agtcctgtgc taactcatat tcattgggga gctttgctcc
    32701 aacctcatac ccacgttcta aaattagctt taacaagcgc tctgctgttt tttcgactaa
    32761 aggcctagcc atacaatccc ttcttcctac ttattgctag ctactattgt acactatttc
    32821 tttttataat tgtagtgggg aatggtattc cagcgctctt taaacaaacc aacaacatgc
    32881 ttaggctggc gatttctaga aaaaagcccc ttatgattgc cttgaatacg gaagatcatc
    32941 agattagttt caaaatcagc aaaattccat acctgctctc caactagatt aggaatctca
    33001 tcaaaaacgc ggtgactcat ctcatagaag cggcactgaa attcctctgt atatggaata
    33061 tcccacatcg aatgaagacc aggaagcgta tctgcaccgt actctgtcat caggataggc
    33121 ttgttaggaa acttcttctg ccattctaat agctcctgac gcagcccaac ctctcctttg
    33181 atcaagtctc catgatcaac ataccaagca taataacggt ttaaggagat cacatcaacc
    33241 agatccatca ccttatctcg atcaggtgtt gctaatagca gattaaccaa tgttactgga
    33301 cgctgctgcg gatctagtgc cttataaaga gcaatcagcg gctcaaagta ttcgtgtgct
    33361 ccctcttcat ggctggcagg ctcattggcc acgacccaca tgacaacaga agggtgattt
    33421 ttgtcacgct tgacgagctc acgaattgct tgctcatgcg cttccttagt tttcatgaca
    33481 gaccaagtgc cattgtcctt tggcgaaaga tccaaggagg ctgtaaagtt ttggaagagc
    33541 cctactgccg gaacctcatc aataaccaag attcccatac gatctgccag acgcatcatc
    33601 tcctcagagt aagggtagtg tgaggtacga aatgaattgg caccaagctc cttgagcaga
    33661 ttcatatcca ttaaattagc tgcttcattc aatccacgac cgttgataaa ggtatcctca
    33721 tgcttaccaa agcccttgaa ataaacaggc ttgccattta gtaaaaattg tcctttttca
    33781 actgcaatac ttctgatacc aaatggctca tcataactat ctacaacatt gccatctacg
    33841 atgatctcaa cgtgggcagt gtatagataa gcatctaaaa cttcccataa acgaacctta
    33901 tcaagtcttg ccttgccatc aatagcctgc gcaacgagct tgtgctcttc atcaaagatc
    33961 gtcaccttaa cctcatcaac agctgctgag gtttcaacag atacctcgac taaggctgat
    34021 gtcatatcct cagacaagtc actcgtgatc gtgatatctg agatatggca ttttggccgc
    34081 accataagct tcactggacg gtgaatacca gcatagttga agaagtcaaa attctccttg
    34141 acaatttttt tgatactgcc atcctcttga gtttcttcac tataattgcc cactggaagg
    34201 ctggtataat ctaaaatatt attggcacaa acagatacct taatttgatt atcctgataa
    34261 tgggtctcag gcaccaacac ctcaaatgga gtgaagcctc ccttgtgttg ccctaaagct
    34321 tgcccattaa catagactgt tgcattgtgc gtgacagagc caaagcgaag taccagctcc
    34381 tcatcagcag caagatctgg cacatcaaca aagcgctcgt accaaaaatc accgatgtaa
    34441 ttgcgcttgt ccttatccac aaccacatca ttaaaggagg tcggcacaac catcagctca
    34501 tcagaggcta ggagctcctg cgggttatgg tctcctagct taaattgcca gagcccccct
    34561 aaatcataaa tctttcttgt ttttgtcagt attgggtata acatacgatt tctcctttat
    34621 cacattatcg ttgaatctca tgcgattcct tggccagtaa atgatcaatg tcatcttgtg
    34681 tcatgatatt actatcaccc tcaatggtat gcttaaactt aaagctagcc attgcaacat
    34741 ctaaagtagc ctgctcgtct ttataactta ataagccatg aatcagccct gccgtaaaag
    34801 catcgcccgt ccctactcgg tccagaacct gaataccaga tttttgggtt ttataaaggc
    34861 tgccattttg atacaggtag gcctttaaca ggtattcatt ggtatagtcc atctctctct
    34921 gggtaaaggc aaagcatttt accccatagg tatcagctaa cctagccagc acctccttca
    34981 acaaggcttc atcatcatag ggtctattca agcctaattg atcctttaaa tcaagcgcgc
    35041 cgcttccctt aagcgtcagc ggctcaatgc caatacaaac atcagccagc tgaacaagag
    35101 gcgacaagag atctctagcc tcctgaaagg aggaccatag actagcccta aaattcaaat
    35161 caaaggaaat agtcaatccc tctgccctag cctttgtcat caaataatag gtcagctcat
    35221 aaagatcact cgttagagca ggcgttatcc cagacacatg aaaccaatca gcctcatcaa
    35281 aaacatgctc caaatcatag tcagcacgct ttgactccca aaaggctgaa tgacagcggt
    35341 cataggtaac ccgacttgct cgcaaagaaa agcccttttg ataataataa agccctaaac
    35401 gctgaccctt ttcgataata tgctcctgat taatttgacg cgaaaagaga aaggtttttg
    35461 tcatttgtcc cagatcattg tctggaatag ctgaaataag agagacctga tgccctagct
    35521 gagcaaggct tgagatgaca ttaagctcag aacctccaaa ttgacaatct aggcttgttg
    35581 cctgctttaa cgtctggtat tgagggggtg acaatcgcaa gaggatttca cccaaggata
    35641 caactttttt cacaacattc ctccttatac tatcaagcta ctctattatt ttataaaaaa
    35701 gtcagccact cctcaaagaa atagctgacc cagcacctaa tccttatcaa caggatattt
    35761 tgtcacatca acatagtcca tgtctgacag tggtacattt ttagcgatag cctgcacgcg
    35821 ttccttatca gagcttgctt tcatcacttg aatcttctct tgaatacgca ccatttcctc
    35881 tttgtcaagc ttgtagaatg acatcaaaat caaagccact agtaaggcta caaatggaat
    35941 accgacatgc agcgcaatca aggccatctt tagacttggg gtaagcggtg tctcaatcgt
    36001 tgggtaagtc tttgaaaaac caataccagc cagcactgca ccaataacca ttggcgcaaa
    36061 tgatgatgca atcgagtcag tcaaggagaa gattgtacca atcattcctg agacataacg
    36121 gcctgattct gatgtttcgt agtctgaaat atcagctccc attgttagca ccaagctagc
    36181 aggcgcttgt gaggcatagc gagcaataat cagtgtcaca gtaaacaaaa tagtgtaaag
    36241 gttaatatga cttaggctga gatccccttt attacccata aagagcacaa taccaaaggc
    36301 taacaagcca accaagccaa tctgaagagc tctgatatat gagaaacgca aacctctctt
    36361 acgagcaata cctgaaaaag caatattaat caaaatcccc ggaacaataa acagcaatga
    36421 gaattgacca gacaaagcat agttaccaaa taaaacacca aacaagataa ccatgacaac
    36481 cgaatcacca aagaattgaa cagcaaactt aaccaaggct gcggcaattg ataggacctg
    36541 tagcggctgg ttgcccttga taaccttcaa atagtccttc agagctgtct tttgcgtatt
    36601 ttcaccaaga ccaaagaatt cctttctgtc cttgctccaa ataccaagca ctgccaatag
    36661 acccaaaata gctgagataa caatcgtgcc ataaatcaac acgtggaaga aggctggtgt
    36721 gaagttacca aattttggaa ccaagaagct tgacacaaca aactgtccac cagtcatcag
    36781 caaggttgtc ataatggcat caacaatgtt aaagattgga cgctgcttcg gatcattagt
    36841 aagggctgtc tgaccagcct tagtgatggt ttgctgcata gagtagccga tcttatggat
    36901 aatcaaaacc agaataaaaa gtggaaaacg aatgttctca ctaactccac ttagaccaag
    36961 cagcagaata agtgataggg ctgtgataat atttccgatg attaggatcg gacgatactt
    37021 accaaactta gtttctgttt tatcaatcaa gataccaatc gcaggatcaa taaagccatc
    37081 aaaaatacga atataaccca tgatctggct gacaaaaata gctgccaagc ctagaacacc
    37141 tgttgaaaag taggtcacaa acataaatgt gaataggtag atattggttg aagcattgtt
    37201 taaagcaaat aaaacaagct gccaaacctt agcgcggtta taggtaacct cttcaaccct
    37261 ttggtcaatt gttttctcca tcagagaaat ccccctttta tcattcgctt attgtgtaag
    37321 cgttttattt ctacatgctt atcttactat tcatctgatg atttgtcaac acaatttaaa
    37381 cttttttcgc ctaattttaa aaaataaagc ttatttagga ttttaatcat taaattcatc
    37441 tgataatttc tggtgtcttt aaaaataatc atcagacaat tactcattga catcaaaaaa
    37501 actgagccct gtgcaataca gaactaaatc ctttcactaa tatgtcgtgt ccaacttttg
    37561 ggggtcagta cacaggatag acagggggtt cttaaaaatc aaaagcccct aaaaccactc
    37621 tcataccaag cagtcttagg agctctaagc attcatgtca ggtgataatc attaggctat
    37681 gaaagccttc agttcttaat cctcaataag ctgaatatca gcccctaagg ctgttagctt
    37741 atcaataatg ttagcatagc cacgtaaaat aaactcaata ttgctaatct cggttttacc
    37801 ctgagccatt agacctgcaa tcaccaaagc agcaccagcc cgcaaatcag ttgccttaac
    37861 ctgtgcccca ctgaggcgat tagagccatg ataaacaatt tggctgccaa gaatggcaat
    37921 atctgctccc atacgagcaa gctctggcac atggttgaca cgcttttcat atatcgtatc
    37981 aatgatacta ccacgaccct cagtccttaa aagcagagga gtcaaaggct gctgtaggtc
    38041 agtggcaaag cctggatagg gagaggtttt aatagtgact gctttcaagg cttcctgctt
    38101 ttccacaaaa atagaatcct cttcaaccgt cattctcaca cccatttcct ctagcttagc
    38161 aataaagctc tctaagtgct cgtaaaggac attggtaatc cttaccccac taccaacagc
    38221 ggctgccaag gcaatatagg taccagcctc aatgcgatct gggatcacct gatgtctggt
    38281 gccatgaagc ctttcaactc cctcaatcgt aatcacatca gtacctgcac cacgaatatg
    38341 cgcccccatg ttatttaaca gtgtcgcaac gtcaataatc tcaggctctc tagctgcatt
    38401 ttcaataatg gtcttaccct ttgcctttgt cgcagcaatc atagtattaa tggtagcgcc
    38461 tacactgata gtatccatgt agatatgagc gccatgaagc tgctgagcct ctgtcatcag
    38521 gtgcatgctt gctccctcat aagatatctg ggcccccatt gcttcaaaag ccttcagatg
    38581 aagatcaata ggcctagggc ctaagtcaca gccacccggc aagcccacaa ccgcctgccc
    38641 aaagcgtccc aatagactgc cataaaaata gtaagaggct cttaggctgt taattttacc
    38701 ataaggcata ggaatatctt gaacccctct ggggtcaatc tccaaggtat ccccctgata
    38761 ggtcaccata gctcccatga gcttcatgat ttcaataaga ctgtcaacat cactaatagc
    38821 tggtacccca tctaaagtga caacatcgtc tgccaaaata atcgcaggaa tgagagctac
    38881 aacgctattt ttagcgcctg aaactgccac ctctccggat aaggcttttc caccattaat
    38941 aataattttt cgcatacttt caaaactttc tgatactaga attcaacctt tttattttat
    39001 cacaaatagc ggtctattac aatcacctca tcaccagctg ctgcaacagg cttaacaacc
    39061 tgcctcttga tcacttttca taacaggttt ttgagaagcc agactcttat ctggatcttt
    39121 cttctgctgc gcaggccttt ttgtctttca tagccgccaa gcctgacaag ttttgctgga
    39181 ctaaaaaagc tcccaaccag cagcacagcc gctagctcag gagctattat acctttaagt
    39241 caatcatcaa ctaaccggcg ctcaatctgc ttaagcaccc tctgacagtg ctgccaccgc
    39301 ttctgtcaat ggagatacct tgtccaattg ttcccaaggc aggtcaatgt ctgttcgccc
    39361 catgtgccca taggctgctg tctgcctata gattggacgc ttgagatcaa gcatcttaat
    39421 gatccctgct gggcgcaggt caaagacctg acgaacagcc gcttccaaaa tactttctga
    39481 cactgttgat gtcccaaagg tatccacacg aactgaaact ggctgtgcaa ccccgatagc
    39541 ataggctaat tgaacctctg ctttacttgc aagccctgct gccacaaggt ttttggcaat
    39601 ataacgagct gcataagagg ctgagcggtc aaccttagtt gcgtctttac cagagaaggc
    39661 accaccacca tgacgcgcat agccaccata ggtgtcaaca atgatcttac gaccagtcaa
    39721 gccagaatct ccctgaggac caccaataac aaaacgccca gtcggattga taaggaatct
    39781 tgtcttctca tctagataat gggctggaat aacagcctta atcacctgct caatcatatc
    39841 ttgacgaatc tggtcattgc ttacttctgg atcatgctgg gttgatataa caactgtatc
    39901 aacacgaaca ggcttatcat gttcatcata ttcgaccgta acctgtgatt tagcgtctgg
    39961 acgcaaatag ctgatctcac ctgattttcg cagtgtcgcc aaacggcgta caagctggtg
    40021 agataaggaa atcggcagtg gcattagttc tggtgtctca tcaattgcaa agccaaacat
    40081 tagcccctga tccccagcac caatcgcatt gaaatcatcg ctttgtcctt cacgtgcttc
    40141 aagtgcttca ttaacgcctt gagcaatatc tggtgactgc tcaaccagag atggatgaac
    40201 acccactgat tctgctgaaa agccatattc tgcctcagta tagccaatct cagcgatggt
    40261 atcacgaacc acacgattaa tatccacata ggcagttgtt gaaatttctc caaaaacgtg
    40321 gaccgagcct gtgtaaacgc aggtctctgc agcaacgtgt gcctctggat ccttggctaa
    40381 aatagcatct aaaatagcat ctgaaatttg gtctgcaatc ttatctggat gcccttcaga
    40441 tactgattca gacgtgaaaa gtttacgttc tgacataaaa atgtcccccc ttaaaaagaa
    40501 tgatacccac cagcacacat gccagatagg attttcctag cctcactcat caagccagcc
    40561 gccaatacaa aaggactgta tccaagctag cctatgacta acgcttagcg agttacaaag
    40621 taccggcttt tagactgcta tcctcagata acaaagccgt cttatcggga cttaataact
    40681 tatttattat accactttta gcgggatttg taagagctcc atcagctttt ttctcaaaat
    40741 aagaaaagga ataccgctac aggcgtattc ctcctcttaa tgtcgtgata atcagcgcaa
    40801 gctatcgatt aaccatggtg gtgctcatcg tgatcatgat gctcatggtc atgcttatct
    40861 gctgcctctt gatcagtatc agccggctta tgctcgtctt caacagcttc tgctggtgtg
    40921 gcattattta gactaccacc ctctgctgcc ttgaagttct tgataattcc ttgtgggaat
    40981 tgtccgcttt cagcagctag ctcctcagct gggaagtggt taccatcagc ctgaatgtat
    41041 ttcagggttt ggttaggctc cttcaaggcc aaggtgttaa tcttgttacg attaacatta
    41101 attgcttcta gggcgagata attgttgaca ccctcaaaat tagtcagctg gttctcttca
    41161 aggttaagag actgtaatga gctttgtgta cctggtaagg ccaagctatt aatcatgttc
    41221 tggttagctg atagctgaat caggctctta ttgtgctcaa gacctgtcaa gctgttaagc
    41281 ttgttttggt caaccactag ctgctctaat gccggtagat ccttgacaaa gctaaggctt
    41341 tgtaaattaa cctccttggc agtgatttcc ttgagagcag aggattttaa ggttgacaaa
    41401 tcaaggtcag ggttgtttga cacaaagagt ttggtcaatt gtcccttgtt tgacaaggca
    41461 ctcaagtcct taatctgatt gtgctctagg ctgacagcga ctagcttttg agcatttgcc
    41521 aaggcagaaa gatctgtaat cttgttaaag tcaaggttaa cggactctag gtttggcaat
    41581 tctttcaaaa tagaaatatc tgtgatatca tttcctgctg ccgaaattac cttgtaatgc
    41641 ggaaaggctt taaggaagct caaatcagaa acaccatttt gagaaatatc aattccttca
    41701 agcgttggca ggttcttcaa gaaatcataa tttttaatgc cggtctgtgt catccacaat
    41761 tgtttgaggt tcttgaactg gtagactggg gtaatatcag tgattggggt aaagccaata
    41821 cctaaaatct gtatattagg catcaggttt aaacctgccc gcttaagagg atccttaatc
    41881 tcaccgatat tgaggtattc aacagtcgcc aaccatgcct tcattttctc taggtctcgc
    41941 tctcttgatg gaaactcagt tggtgcattt gcatggataa tggacgaaat cacttcctca
    42001 tcaaagccaa gctttctcag agttgccata ccgattctat ccttagcatg cggatctact
    42061 gcatgaggat caaaaggttt tgataaatca atatcgtcaa tataggttgc atgacgatgg
    42121 tcaccatgtg gatagtcaag aatgatacct tcttctgtat gctccacacg aatgctgtcc
    42181 tcaggaatat ttaatgactt agccaaatat gcttttttca aagcaatcgt tttctcaaga
    42241 tcactttgtg gcttagctgg tgcttcttcc tttggctgtt cgattaaatg cttccacttg
    42301 ctgttacgca agctttcata agtgactaaa tgattgtggc cattgtgatc aacaatcaat
    42361 ccatatgatg ttcgaccgac aatacctgtc ccgtcaaaca agaagccatc acttgttggg
    42421 taatcaacac ctgcaaattt tccagacggt gatgatggag ctgatagtgg cacatggtta
    42481 ggcactggat aagctacctg accacctagt gagcttttta ggatatagtg gtaatgatca
    42541 ccatgacgga caatatagcc caaggcgtcc tcagctacaa tatcagctgg gttaaacaca
    42601 tagtgatggt gcgggtcatt agcactagta tggtgatgac ctgatgctgc cttggtctgc
    42661 tcaggcttgt ttaggtcagc gtcctttgga atcaggtact caaacttgct gcccttgaga
    42721 tctgcataaa aaataaaatg cgaatgccca ttatgctcaa caacaatacc gttttctgtt
    42781 ctagataaga tttttgaatc cttggtcaag ataaaaccgt catcagttgg aaagtcaatc
    42841 cccgctactc ccttacggtc ttttcttgtt tgcttaacct ttttagactg tttctttttg
    42901 gtcgcttttt tagctgtctg ttttgtctta ggctgatttg ttggctgctt tgtcgactga
    42961 caagctgtca gggtcaggtg acaagccata aacaggctag ccattagcat taatttttta
    43021 cttttcatct ttcctccata aattaactgg ttaaataaga tattaactag ttaaatatac
    43081 caaaaaaaca aataatttca actgttttct tatttttaat tcattctcat tcaacaatca
    43141 tagtagcttg gctaggttgg cagaaaaatg agcctctcct actctcatca aataaacaga
    43201 tagccttaat gatggctgag ataacagcat acaaagtcgt taaagtcact tgtaagaaaa
    43261 agaaggacat atcttaccac cactatcttg ctcatcaaag ccctacggct ttcagacaaa
    43321 atcttcataa cagcggaaag gctgatgaag cagctcagac aaaaagagca agctccttaa
    43381 cgtcaaggat cagagatcag cacaaaaata acagcaggct acattaagaa ctgcaattcc
    43441 ttgaaataga attgcttttt tacaaaaaaa tcgtctccct agactgttcc atcatctcac
    43501 gtcatttgta ttatttgctc ttgaaatcca gtcattttat actatactag aattatgaag
    43561 acatctgaaa aaatttacca attactagct tgcagcgacg actatgtcag tggagaatac
    43621 ttggcagagc agctcaagct ttctagaacc tctgtctgga aatccatcaa aagccttgaa
    43681 agtcaaggcc ttcacattga atccctcaag cataagggct atcgccttat tcaaggagat
    43741 atattgctgc cagagctcat cagccaagag ctcaacatgc ctttatctta tcatgagaaa
    43801 agccagtcaa cacagctaga cgccaagcaa ggaatcgagc taaagcatac tgctcctagg
    43861 ctctatctcg ctccaagtca gtatgcggcc aaggggcggc ttaatcgcca attctttgcg
    43921 tcacctcatg gcggcattta catgtccttg catctcaagc caaatgttcc ttacgcagac
    43981 atgcctcctt acaccatgat ggtggcctct agtattgtta aggctatttc aagattgacc
    44041 ggtattgaca cccaaatcaa atgggtcaat gatatttacc ttggccataa aaaaatcgcc
    44101 ggtatcctga ctgaggccat tacctctgtg gaaacaggcg tcattactga tgtgattatt
    44161 ggcgtagggc ttaacttttt tgtaaccgaa ttttctgaaa acctcaaaga acgagcaggc
    44221 tctcttttta gcaacaagcc tagtattact cgaaatgccc taatcattga catttggaag
    44281 ctctttacca caataccaat caaggaccat attaaggtct acaaagaaaa atcacttgtc
    44341 cttcaaaaac aagtgagctt ccaagaaaat gatcgtcaaa aaacagcaac tgccattgac
    44401 ctgactgatg aaggacacct catcgttcaa ttagacaatg gtcagctaca ggtcttaagg
    44461 agcggcgaaa ttagtctttc ttcctggggg gattaacagc attaatgatg tttttggtaa
    44521 attggtcaat agcataagca cgccttaaat ctctaaagag caaaagaccc caaaacagag
    44581 caaaaatata atcgcctgaa aataataaat cgctgaaaaa ataagcttca aaggcacaaa
    44641 tgaatgccat aaacataaat tgtcgaatag tcatactact attataccaa gaaaactaaa
    44701 tttccactaa cgattttcac gcagcttgaa gaaaaaggca gttagcctgc ttcaagcttt
    44761 tttgctgctc tttgatagcc tgtaacagtc aaataaaaaa gagctcactc taaaaacgac
    44821 gccaaaagcc agcttgattg ctaggcttgt agtcaattgt ctcaaatcag tgaatcacta
    44881 agccttataa gaactcagtc attgggtcac aatgacacct agctctaagc agcaaaaaag
    44941 agaaccacac cggtcctctc tagcttggct tgtcagctat ctattagtgc tgacaatgag
    45001 ccctgtcatc tccttattct agacaattga tacactacca atcatcagct agcgctaatc
    45061 ctctatgaga tgaatcttat cagttaaaaa gtcaaacccc tcaggcatgt caaaggtcgc
    45121 ttgctcagac tctttggctg tctctttttt ggttttgatg gtcatggcaa actccgagcg
    45181 aatatggtgg aagtctgcct ttggtactgc caagatatga ggagaaaacc ctgctgcctt
    45241 actcatgata ttcccaaaca tatcattcaa atcctgacgc ttcatggcct gctcagcgtt
    45301 aaaggcggcc tcaaaggcca aaatagcatt ttcactattg gctaaaacag gctccgagcc
    45361 tagtaacaaa gctcgatcct gtgcagaaat actatctaaa atctcattcc aagcactttt
    45421 tagcgcttct aaatattgtc gtgactgctg gctatcttga acagtttcct ccatgatttt
    45481 caatatcttt tcccgatcaa ccttgtaggt aaaggccttt ggcttgatgg aatgagctgg
    45541 tgtagcctgc gcagttagac ccttttgagc ctgtagctgt gatatcgtct ccctcagctg
    45601 actaatctca tgcttcaagt catcaacatc agctagcagg ctagacggta tcgcagtgtc
    45661 tgctgcttgt ccttgctctg ccagctgaat ggtcatcatt tcagcgtaga ttctaggatg
    45721 ggttcctttt ttgatctcag gcaaatgctt ggttactgta gcaatcattg taaaaagctg
    45781 atcaaaagac actgcaaggt tatcatcaaa aagagctgac tgcctgtgat gatcaccacc
    45841 tgatttcaca atgagcaggt ctctaaaata ggttagcaga tccgttgcaa agcgactcat
    45901 gctcttgcca ctatcataaa ttgtttctag attagctaag gcctgacttg ttttttgcct
    45961 gatgagatgc tgaacgtagt cgtctaaggc cgaaatagaa atagagcctg tgatttcttc
    46021 tgcaatagca agcgtcactc gattgtcaaa ggataggctc aaggcctgat ctaaaatgga
    46081 tagggcatca cgcatgccac cttctgctcg tcttgcaatt aaatgaagcg cctctatttc
    46141 ataggctatg ccctccttgt ccagtatcgc cgccaaatgc tcacaaatag ctggctgctt
    46201 aatggcttta aattcaaatc gctggactct agacaaaata gtagctggaa tcttgtgtag
    46261 ttctgttgtg gctaggataa aaaccacatt gtcactcggc tcttcaaggg tctttaggag
    46321 cgcattgaag gcccctgttg atagcatatg cacctcatca ataatataaa ccttgtaggt
    46381 tgcccggcta ggagcatagg ttgacttatc tcgaatatcg cgaatttcat caacaccatt
    46441 attagaggca gcatcaattt caatcacgtc ctccaggctg ccagttgtaa tatctcggca
    46501 aatatcacaa tgattgcagg gctctccctt gacctgatta gggcagttca ttgccttagc
    46561 aaaaattttg gctgcgctgg ttttaccagt tcctcttgga cctgaaaaga ggtaagcatg
    46621 gcttatcttt tctgactcaa cagcctgctt taaggtggtc gaaataactg actgcccaac
    46681 catttcagca aaggtctggc tacgatactt ccggtaaagg gcttgataca ttaattctca
    46741 actccaaaca tgtcaaaacg aaaagatgta ttttctagta ataaggctac aaattgctct
    46801 aaatagtctt gatctatctg atcataatca gcaacaagac tggaatccaa atccagaaca
    46861 ccaacaagcc tgccagcctt aagcattggc acaacaatct cgctcatggc tgctgaatca
    46921 caggaaatgt aattagcatg ctttttgaca tcatcaacga tgatggtttg accagattga
    46981 gctgattctc cacatactcc cttgccaagc ttgatatgca cacaggaaac ctttccctga
    47041 aagggaccaa ggatcaattc ttgaccatca aaaaggtaaa agcctgcaaa aacagaatga
    47101 ggcagggtca tttttaagag ggcactagca ttagagagat tggccaaggc attgctttca
    47161 ttagaaaata aggctttagc ttgagccaat aatagctgat aatgttcaat ttttgtcgtc
    47221 ttattcatgg ttcttattat aacatatctg ctactaatcg ttaaacgatt tccacaggaa
    47281 aagaatttta atcagcctct ctagaaaaga aagagatttt atgataaaat agtgagtaat
    47341 attaaaaaaa taggagagtc agatgccgtt gttgagatat aaaaagatta tcgctacgac
    47401 cttatttatg ttattagtgt ttaatggtat tgagtatgaa tgtctaaacc ttgtcagtcc
    47461 caaacaaacc ttttaccaat ccgctgcctt aatcctctca accagcctac tagggatcta
    47521 tctgattccc ttttcactgg ctattgctta tctcaagcgc atctaccaga taaggatctc
    47581 aaccctgcta ttagctgggc taggcggtct ttatattagt ggctttttag cctcctttgg
    47641 caatcaggtt ttagagcaat tttggattag cctgataaag cccaatattg ccttagagga
    47701 gtggacggga gctttgacag ggccttttgt ggaagagcct attaaggcct ttgcagctat
    47761 gcttgtcatt tatttgctgc cagctattaa tcttaagcaa aaattagtca tcagtctcat
    47821 ttctggcatg ggattccagc tgactgagga cattagctat attgcaagtg cggctgatcg
    47881 gtccataaat gacattttgc ctacaacgct tgccaggatt agcagctcac caaactctca
    47941 ttgggtctat actggtattt ttacaatggg agcatacctt ttaattaaaa aatctcaatt
    48001 attcccaagg tctctgcaga ttttctgggt ggtaagtcct ctagccctac attttatatg
    48061 gaactctcct atctcagatt tagctggtgt cgcagttatt catggaacaa taacaaccct
    48121 tatctttatc agtctattca aaaaaatcca tgccctagac gacagcatcg cctactagcg
    48181 tcataggaca cgagcaacca agcccagccg catttgggca tgtgatggct catatgcata
    48241 tatagctact cacctctcgc ttaagctata ggcagctaaa tacctatcac aatagcagaa
    48301 aaaatgacta ccagtcttaa aagggctagt agtcatttta agctaaaaac aagcacttct
    48361 tacaggatat accactgata cagataatag caaagcacaa gggtcatcag tatccccata
    48421 taccatgaaa ggacaaaata ccatttcttc gttttatggt taaaataatg cccagctaga
    48481 taggctccaa tcccaccaca taagagtgac aacgttaata gcattttctc agaaagtcgc
    48541 cattgacctt tttgggctct gtgtttatca ctgccatagg ccgcaaagac cacagcattc
    48601 caaccaaaaa gcaagattag gcttggtagc atttgtctgt ctccaatcac agcactacag
    48661 ctcacctaag atgctggcaa tctttgtgtt gatgagatca atagcaacca cattgctaac
    48721 cccttctgga atgacaatat cagcatagcg cttacttggc tcaataaatt gatgatacat
    48781 cggcttgaca acgcttgtgt actgctcaat aatgctctca aggcttctgc cacgctcaac
    48841 catatcacgc tgaatacgac ggataatccg aatgtcatca tctgtatcaa caaaaagctt
    48901 gatatccatc agctcacgca aacgctcgtc ctctaatacc agaatcccct caacaataat
    48961 gacgtcctga ggctcttggc gaaaagttct gttgctgcga gtatgctcct tataatcata
    49021 gattggaata tcaacaggcc ggccagccaa gagttccttt agctgctgaa tcatgaaatc
    49081 cgtatcaaag gctaacgggt gatcataatt agtcttaacc ctttcctcaa agctgatatg
    49141 tgattgatcc ttgtaatacg aatcatgctg aatcatcgca attctcgcat ttggaaagct
    49201 atttaaaatg gcacgagaca cgctagtctt accaccacca gaaccaccag tcacaccaat
    49261 aataatgggt tttttaagca ttgtaaactc caaatctaaa agtctttcgg tctattttac
    49321 caaatttgcc actataatgc tataatgaag agaaaacaaa ataaaaggat agatatatga
    49381 taaccaacct tcccactcaa tggcaggaaa agctggcaaa gcttggcttt actaatctca
    49441 ccccaatcca agagcaggtc tttcagccca ttgttgatgg caaaagccta ttaggcatta
    49501 gccccaccgg aacaggcaaa actctggcct atttatggcc aagccttctc aggctaagcc
    49561 ctaaaaaagc ccagcagttg ctgattttag cacctaatac tgagctagct ggacagcttt
    49621 ttgaggttac caaggaatgg gcagagccct taggattaac tgcgcagctc tttatttccg
    49681 gaagcagcca aaaacgccag atcgaacgcc tcaaaaaagg cccagaaatc attatcggaa
    49741 caccgggacg catttttgaa ttagtaaggc ttaaaaaaat caaaatgatg gccatcaata
    49801 ccatcatttt agatgaatac gacgacctac tgagtgactc ccaataccag tttgtccaaa
    49861 aactctccca ttacgcgcct cgtgaccatc aaatgatcta catgagtgct actaacaaga
    49921 tagagcaagc cagtctagcg gatcatacct tggtcattga tctgtctaag caagcattgc
    49981 cttgcattga gcactgctac atgctggttg acaaaaggca tcggaccgat atcctacgta
    50041 agctagcaaa tattcctgac tttcgtggtc tggtcttttt taacagcctg tcagacctag
    50101 gtgctactga agaacgcctg caatatagtg gagcttctgt tgcttctcta gccagtgatg
    50161 tgaatgtcaa gcagcgaaag gccattttag aagcctttaa agagcagagc atttcactgc
    50221 tgcttgcgac ggacatagtc gctcgtggga ttgatattga ccagctagaa tacgtcatta
    50281 acgctgaggt tccccgtaat aaagagcaat atactcatag agctgggcga accggtcgta
    50341 tgggacgatc agggattgtc ataactcttg tcagtcaccc tgaagacatc aagcgcctta
    50401 aaaaatttac caaggtcact gagatgtact tgaagcatca gcaattatac caaaaagaaa
    50461 taagaggcta gctcaaagga tataaaccta aaaagcttgc ctccaagtat gatgtaaagc
    50521 aactaatcac tatttcttac ccttgctact aaaaaaacga acgtaaagtc cttctgacat
    50581 gaagtcaaaa ccttacgttc gttttatatt atactgacac cactggcttt attagtatag
    50641 tagatactgg ccatgcttag ccagactaga tactttcttg aagtgagccc gccatttagt
    50701 catgctctag agccttactt gctttttctg actgactagc ggctaccata tagctcagat
    50761 aaggtcacac atttgtatcc ttccgctttt aggtattcca taatacttgg caaggcatct
    50821 acactggtct ggtgaatatc gtgcattaga acaacccctc caggctgcaa ttgctgcttg
    50881 acatttgcca tgatagcagc agtattacga ttttcccaat ctctggtatc aactgtccaa
    50941 agcatttcct taagacccga tgcccttcta acaatatcat tagtagctcc ataaggagga
    51001 cgaagataga ctgggcgttt tccacaggcc ttttcgatgg cttgattggt cgtattgatc
    51061 tgtgtttgga tctgatcaac ggttagggtc gtcaaatcag ggtgatccca agaatgattc
    51121 tcaacatcat gaccagcagc actaaccttc ttaaccaaag cctcatggcc aacaacctta
    51181 gaccccatca taaaaaaggt ccccttggcc tgatatttgg ccaaaatatc taaaacctgc
    51241 ggtgtggtca cagggtctgg accatcatca aaggtcagag cgactagctt ttgtccctct
    51301 ttttctgcct cttttgcctt cttttcctcc aaatactctt cataagcagt cttgtctgaa
    51361 ccctctagaa aatctggatt aatcacatca aacaggcttg caagaggtat tgacatatga
    51421 ccaaataaaa taagattacc cgaatcaatg gcaaagccat cgcttaatac ctgatttttt
    51481 tctatcatcg tatcagtgct cagcttgatc tctttgcctg gataaagctt gccaacctct
    51541 tcctcgatgc gatctaagcg accagcaact agctcctcta gcttaaaggg gctataatcc
    51601 tctttcacat ggtaacgact aacagccttt tctgtagtct tttttagacc aaataactga
    51661 ggcttgtaga ccgtcttgta gataaccaat tgattgacct gcttgatatg tgaagcctca
    51721 agcttaggct ttaccatgat aacagccttg tcagtctgct tgccttgata cagagacata
    51781 ggcagatttg acacataaaa atcgtcagcc ttctcaatcg gagacaggta ataccaatcc
    51841 tgctttcctt tcttgagata cttgaccttt ttgatctttg gactatcctt agaagcagtc
    51901 tgttcgagct taatgactct ctgagtatcc tgccctattt tccaagatct aatgaaggta
    51961 aacgcaacac cgaccaacaa taaacttaat aaaataatga gaatataatt tagctttttc
    52021 aatctcgtcc tccaattacc ctacaatttt aacacaagat agttggaaaa taaataaaaa
    52081 aagttaggtt tccttaactt ttttcagtcc aaaataaggg caaaaaagtg ttttatggtg
    52141 caggatttgc ctgagttatt ttccctttat cacagccatt tgtcactgga taaggggcta
    52201 gatattatac ctaaagcttc tctttattgc tatcattatt ctgacattct taggcatgct
    52261 atttcccttg ataggacttg attgctgttt ctttagcttg taaggatctc ctaaaaatga
    52321 gagtattttt aagcctataa tttatatatt cgaaaaattt tgacaaaaat gaggaaaaat
    52381 attgatttat ttagctttag tgataaaatg agggtgaaaa attaaataaa ggaggacatt
    52441 gatatgtctc agaagttggg aaaacaactt attcgctctg ttgttactgc cttagccgcc
    52501 atagcatttg gaatatttcc tgcaagcgag acgactaatc atatcaccta tgcagaggtt
    52561 aactccttaa ccccttcggt agaatggcct ttagagcagt atcctaatta ctatagcata
    52621 gaaggaaagt ctaatatcaa caccaaggat tttcctaagc tatacaccac taccgaaaag
    52681 gtttacaaaa aaagtggtcg aagcactaag cgcgttactg tttctgatct gcaatacgct
    52741 gcacttgatg gctatggccg ttcaggagct gcctatggta ttatcacaaa ggatatgatc
    52801 gcgatgtcag ccggataccg cgaaaaatgg gaaagcaatc ctgagccaag cggctggtat
    52861 acatatcatt tcaaagaaac tggcaagcta gctactgagg ccgactacct tcacagcaaa
    52921 agcaagatca aacgaacctc aaacaatagc tatgaaagca tcgtccttag caacggtaag
    52981 attcgcaacg gctatctttt tgatcgtagt catttaattg ctgacagctt aggtggtcgt
    53041 ccttttagaa ataatctcat cacaggtaca cgtactcaaa acgttggcaa caacgaccgc
    53101 aaggggggta tgcagtacat tgaaaacaaa gtcctaaact atattaacca caaccctcag
    53161 gttcacgttt attacaaagc cgtaccaatc tactcaggct ctgaattact ccctagggcc
    53221 gttgtggttt cagcgctctc ctctgatggt aaaattgatg aaaccgtaag agtctttaac
    53281 actgtcaatg gctttaccat caattaccaa tatagcggca tcagccatga taagggcatg
    53341 gaggcttcta gtgagtcaga agctgaggat attacagacg aaagcactcc agtagctgaa
    53401 ccagctgatg aggaggctat ggagacagag gctgctgcta acgacacaat agtctatgtt
    53461 acaagtaatg gccaatcaaa ggtatactgg tataataagg accatctgcc agagaaggtc
    53521 aatctcaata aggttgtaga aatgaccgag caggaagccc taaatcgagg aaagcaccat
    53581 tcctccttag aaaaaataaa tcaatagtct cataacgact aacacaagag ctggttgaag
    53641 caaccagctt tttttgtgtg atgaaggatt agacagctcc ttagctaaaa gataaagagg
    53701 ctgataaagc actcaacctc ttatcgcttt tataaatgct ctggtactgc ggctaatagc
    53761 tctgatagct tgcttgcatc actaccacct gccatcgcca tatctggctt accgccacca
    53821 cgacccgaca cgattggcgc taaggcctta atcagattgc cagcgtgagc tcttttatcc
    53881 ttacttgcaa caagaacatt gaccttctca ccaatgcttg cagccagcac aaggacatct
    53941 gaataatctc tttgcttcca attatcagca aaggtacgca agactcctgc atctgatacg
    54001 gatacctcac tagcaatgta acgtagaccg tttgcttcct ggaccttttt aaagacatca
    54061 ccagcctgag ctgctgctgc tttttctttt agctctgcca tttctttttg caaatcgcgg
    54121 agctgctcgc tgaggctcac aaccttactt ggaagctgtt ctatttgcgg caccttaagc
    54181 gtatgtgcaa tttcttttag gatgtcttct tgcttgcgga agctttcaaa ggcctgctga
    54241 cctgtcactg ctatgatacg acgtgttcct gagccgatcc cctcttcctt gataatcttg
    54301 aaaagaccaa tttctgatga gttggacaag tgagtccctc cacaaagctc aacagaataa
    54361 tcgccaatct gaacaacacg aacagttttg ccatattttt caccaaagag ggccatagct
    54421 cccatagcct ttgctgtttc aatatcagtt tctgtggttg taatagctaa tgccttccag
    54481 atttgctcat tgacctcttc ttcaatacga cgcagctcct gggctgtaac ggcttcaaag
    54541 tgtgtaaagt caaagcgtaa aaaggcttct tcatttaagg aacctgcctg agtggcatgt
    54601 tctccaataa ccttgtgaag ggcagcatga agcagatgag tagcggtatg gtttttctca
    54661 acagcatagc ggcgcttgtg atcaatagca agagtataaa cagtgtctaa tgcaaggctt
    54721 gcaagaacct caacagtgtg aagaggctga ccattcggtg ctttttgcac atctatcaca
    54781 cgagcaacaa ggtcaccctt atcatttttg ataaccccat gatcggcaac ctgaccaccc
    54841 atttcagcat aaaacggtgt ctgatcaaac acaagcaagg cctgtccttc tgaaaccatc
    54901 tcactacgct cattatcaac gatgataact gataagcgag aggcaacagt ctctgtttcg
    54961 tacaaaaatt ctgatggctc tgtgatgcct gccagtgtct cattttgcat gcccattgag
    55021 ccacccttaa cagctgctgc acgggcacga tcctgctgct ccttcatagc tgccttgaag
    55081 ccttcatgat caatcttata gccagcatct tctgctaatt cttcggtcaa ttcaactgga
    55141 aagccatagg tatcatacag cttaaagata tccttgccat caagcctgtc ttgccccttt
    55201 tcctttagct gcgccagcaa ttgatccaaa tgccctgatc ctgcatcaat ggtacgtgca
    55261 aaggtttcct cctcacgctt gataattttt tcaataaagt cacgcttctc aagaatctct
    55321 ggataatagg actccatgat atgacctaca gtagctacta gcttataaag gaaggtctca
    55381 tgaataccga gcctacgacc atgcataaca gcacgacgaa gcaagcgacg aagcacatag
    55441 ccacgacctt cattaccagg tagggcacca tctccaatcg caaatgacaa ggcacgaatg
    55501 tggtctgcaa tgaccttaaa gctcatgttg tcaccatctt ggtcgtaagt atggccagat
    55561 agcttttcca cttccttgat gatcggcata aataggtcgg tttcaaagtt tgtttttgcg
    55621 ccctgcataa cagccacaag acgctctaag ccagcacccg tatcaatgtt tttgtttgga
    55681 agctccttgt actctgagcg aggaattgta gggtctgcgt taaattgaga caaaacaata
    55741 ttccaaattt caatataacg gtcgttttca atgtcctctt ccagcaatct aatcccaata
    55801 tgatcaggat cataagcctc accacgatca aagaaaatct ctgtatcagg tcctgacggg
    55861 cctgcaccaa tctcccaaaa attttcctct aatggaatca aatggcttgg ctcaacgccc
    55921 agagcaatcc aacgattgta agagtccttg tcatctgggt agtaggtcat gtataatttt
    55981 tcctttggaa aatcgaacca ttccggactt gttaacaatt caaagcccca ctcaatcgct
    56041 tcgtcgcgaa aataatctcc gatagaaaaa ttaccaagca tttcaaacat agtatggtga
    56101 cgagctgtct taccaacatt ttcaatatcg ttagtgcgga ttgacttttg agcgttggta
    56161 atacgaggat tttcaggaat gactgaccca tcaaaatatt ttttgagggt ggccacacca
    56221 gagttaatcc aaagcagggt tgggtcattg actggcacaa gattggccga aggctcaata
    56281 gagtgacctt ttgatttcca aaaatcaagc cacatttggc ggatttgggc tgatgttaac
    56341 tgtttcatga ttaagatacc aagagcgatt agagagactg ggtatgattg tccttagcat
    56401 aagtagcctg gggagacgat ctctactcgc attcagttcc tttcgttgat tttttatggg
    56461 attaggctaa aagccatcaa aacaaaacaa gcccatatca cagagggcga aaaccgcggt
    56521 accacctcta ttcaatgagc ttgtcattct taattactta tatcagataa aatcacatta
    56581 agcagcatgc ctatcagatt atccgtaact cacagcaacc gtcacttctc tgggtcaaat
    56641 ccttgataaa caattcttaa ctaaaccagt ataaagcttt tttgagcatt cgtcaatgaa
    56701 aatctatttt tctgacttag atttagaaga ttgactatcc ttgcttgagt ctgaagatga
    56761 tttctgatct gacttgcttg tgttcgcctt gcttgctttt ttatcagtat tggcatactg
    56821 tgccaagata ttagcaaatg cttggtcttt gatcttaaca tttgccttgt ctaaggcctt
    56881 tgcaatgacc ttattttgga aatcaatgtt ttgtgtcttt tcagccaaga caatttcttt
    56941 tagacgtttc ttatatttct tccaatcaga agccttttcg gcttttttgg ttaccttaac
    57001 aatatagaac ttgttttgat aagtagccgg atctaagaca gaaaccacct ctgaaatatc
    57061 accctctttt aatcctgagg cggccttgat cacatctgct ggtaacttag tgtctcctga
    57121 gtcaaactta tagtctacct tcttgtctgc tgctgttgtc ttttccttag caatagcagc
    57181 aaagtcagca ccctcagcct taacctcacc taaaacagcc tttgctgttt cttcattgtc
    57241 tagagtagtg acctgagtag tcatttctgg tgtgtatgac tcataggctt ttttgtaatc
    57301 agcatctgtc agctcttttt tagctgcttc tttaacagca tattcaacca gcatggctga
    57361 gcgaatttga cgcttgtagg tatctgttgt caagccagac tgcgcaaggg ctgcagagaa
    57421 tgacgcaccg tattgctcag ctgatttatt gtaagcttct tccgttcttt tcttagaaac
    57481 ctttttaccg tattggtcct caaaaacacg actaaccaca aggtttagca ttgctctttg
    57541 agaaatctct gtattttttg tttcattgta aaaatcacta acactgatag tgtcgccctt
    57601 catcgtaatg acacttgtat tgtcatttgt agactgacag gctgctaggg tcattgctga
    57661 tgctagggtt acgataccag caagtaattt agttgatttt ttcatgtgat tttgtgctcc
    57721 tttttgtcat taaccagtat attatatcac aatttcttaa acgtaactta atctaacaaa
    57781 cgaatatctg cttgattttt acgaatcatc agcaagccat cactaagcgg cagcaggctg
    57841 gctgtcaatc caggattatc aagagttgct gcaaataagt cctgaaggcc acgataaatc
    57901 gtgcgctgtc ctctccgaac ctccttgatc ggcttagcaa tgtcaccccc ctgaaacaca
    57961 tcatctaaaa caaccattcc acctattttt aagtgcttta acacctctgg aagaaactga
    58021 atgtattttg attttgcaga gtccataaaa acaaagtcaa actcgccagt aagtcctgct
    58081 aaaagatcag ccgcatctcc ttcaagaagg gtaatttgct tgcggctatc gtattttgca
    58141 aaattttcct tggcaaagcc aatcatctca gcattgcgat caatcgttat aatctctgcc
    58201 tcaggagcat tttctgccat tagcaaggca gaaaagccaa tagctgtgcc aatttctaaa
    58261 atccttttgg gctgcaagct ttgcaataaa agcctgaaat aagcaacaac ctcatgctgg
    58321 ataatgggaa tattttcttg tctggcaaag gcctcaagct ctgctaaaaa gccttcgttt
    58381 tgctttagct gcgttcgcat gtagtgaaca atgtcttctt tgacaataga gcggcgcata
    58441 ttatgatttg catttttact atatgattta accatgctat ccattatata aaaaaactct
    58501 aggtaatgct agggctttca ctagcctatt cacctttgac gatctgagta gtatctatca
    58561 aaggagctca cagacagcct taagctgctt gacaatgcta tcacaagcag acaagtcctg
    58621 taagggataa tcaggattgg caaagccgat acaggtcatc tgagcagcct tagcagcctg
    58681 actaccatgc ttactatcct caatgacaag gcaggtcttg ggatcaacgc ttaaccattc
    58741 agcagcctta agaaaaatat ctggcgctgg ctttgagcga gcaacctctt caccactaac
    58801 taacacctca aagcagtcca aaagacctag tgcagtgaga tttctaataa tatctgcctt
    58861 aggcgatgag gaagctactg ccaagcgata gcccttcgca tgcaggtgct tgattaattg
    58921 agcagcacct gctatggcct tgacaccgtc acgctcaagc attgcttgac gacgatgatt
    58981 catctcagcg atgagggctt caacagaatc ctctagctga cactcctttt tcatagttgt
    59041 ccacatatcg tcaaaggtgg ttcccataaa ctggtactga tacgcttcat tggtatctat
    59101 gcctcggtcc aatagcattt gtgtcttggt tgacaaaaag atatattctg agtcaacaat
    59161 cacaccgtcc atatcaaaaa taaggcttgt tttcatcatc tacctcctct tatgctatat
    59221 ctcagtcagg tcaagagcaa gactattaat tactagagct atttttacca gaaaaaagct
    59281 caacaatatc tgacagctga ctaatatgat gattatcatc actatctggc agcaataggt
    59341 tgatagagct aatcccagct gcccttgctg cagcaaggtc taagggccta tcaccaatat
    59401 agtaggtctg cgacttatcc atctgataat gatgaatgag aaaaagaagc gcttcagggt
    59461 ccggcttacg cttaaagcca caatctgctg taatcacctc tgtaaagtaa tcagcaatcc
    59521 ccagacgctg caaaacagcc tgagtggttc gtcctttatg agtcacaata aaaggcttaa
    59581 ccccctgctg agaggttaag gctaatgttt ccttggctgt aggcattagt gctattaggt
    59641 gatcacgcgc ttcctgctct cgggtaaaga aggccagcaa ttctgaaaaa tccagctgat
    59701 gtgcctctgc taacctcttc aaaagctgtc cgatggattc ttgaataatc gtatccataa
    59761 cccaagcctc atcaaagggc agctgatagg tctgatacaa taaacctagc gcctgacgaa
    59821 tagcctcaga ggattggact agagttccat caaagtccca aatgagatta actgtcacaa
    59881 tccttacctc ttaaatcaat ccaataacga gcaatagcct gccctgctaa gcttgtagta
    59941 gggtaatcat ctgccacctg aacaatatcc tctaaaatac caccagcctt ttcaatggtt
    60001 tttcgactgg ctatattatc tttattagct gttattaaga cacgcttgat cccacgctct
    60061 tgatattgct gtaatgcaaa ggccagcaag tctgtcataa ttccacgccc gcgataatct
    60121 gtccttgtca catagccaat atgtccgcca attgttgcta agtctccttt ttccaactgc
    60181 cagcgacagc ctattctagc cactagctga ccatctaaaa aatagtaata attagtgcta
    60241 gtggaccagt caggatgatc agtttggacc tcaaaccgtc tagattgctc aacaaaggct
    60301 gcaaagtcct ctactttttt ggtctcaaca aaggtattac ctgaagcttt ttcagctaac
    60361 agtatatcct gaaagcgctt aaaggctgct tgatcagcta aagcaattgt tctaatctct
    60421 ttcatgcctg gctccttttt attatgctaa aaatcaactg ggcatttctc aagcattcat
    60481 catgccaacg aaaaagagct gcccctagaa ctgttgatgt aatactacgt ctagaggctg
    60541 cccacaggcc tttaagctag gctgatagac actgactgct gctatttacc aatagctcaa
    60601 aacctaagag gagatggcaa ctattagaga tgtgcccctc ttgccactaa gtcctctagc
    60661 tctgtcaaac gctcttcaaa gaccctaaag gctgcttcta ggtaatcacc cttagccata
    60721 tcaacaccag ccttggcaat cacctcaagc ggataatctg aatttccaga cttcagatag
    60781 gtcaagtagt gatcaatatc ctcttgagta ccatgcacga tcttatcagc caagtagctg
    60841 gctgcagcaa agcctgttgc atattgatag acatagtagt tgtaatagaa atgcggaatg
    60901 cgagcccact catactggat aaaatggttg tcctcttttt ttaagccata atatttttcg
    60961 tttaaatcag catagagatt attgaggtat tcacttgtta acacctcgcc attttgatcc
    61021 gcctgatgaa tagcgtgctc aaactcagca aactgtgttt gacgaaaaac cgttccacga
    61081 aaaccatcta ggtaatgatt caaaatagca aagcgctcct tatcatcctg cacctcatgt
    61141 aacaaggcct cagtcatgat attttcatta gtggttgaag caatctcagc taagaaaatg
    61201 ctgtaatctc catacacgta aggctgtgtt tcacgcgtaa aggttgagtg caggctatgg
    61261 cctgtctcat gcactagcgt atagaggtta tcaagcgtgt cctgccaatt taagagcata
    61321 aaggcattgg tatcatagga accaccagag taagctcctg agcgtttgcc cttattgaca
    61381 tgcacatcaa tccaacgctc tgtaaaggca cgatgcacac gctctgaata atcctggcca
    61441 aaaacagcca aaaccttctc tgctttttcc aaggcctcat catagccgat agcaagatct
    61501 gtctcagata aaggagtata aacatcatac atctttagat catctaaacc aagcacctct
    61561 tgacgtagct tcaaataacg atgaagcagc ggcaaatgct tattaacgtt ttctagtagg
    61621 gtatcgtaaa cagcctctgg gataaagttg gctgacatcg ctgcctgacg ggctgaagca
    61681 tatttgtgaa cacgtgcctt ataattttgc acctttacat tggtttgcag ggttttagca
    61741 taggtgtgct ggaattgctc ataagtacta tacatggctt cataggcagc cctacgcacc
    61801 ttgcggtctt tcgattccat caagctaatg aaattaccat gtgttagctc aacctcttct
    61861 cccttatcat ttgtcacaat aggaaaagca atgtcggcat tatctaggat actaaaggtc
    61921 tcctcagcac cattaaagat ttcttgtgcc cctgctaata gctcctcctc agcctgacta
    61981 aggacatgct cacgcgtctt gaacaattta tcaaagaaat ggtcatagac tgttagctcc
    62041 ggtgtctcag ctaagaaggc ttggtaggct tcctgactta aggccataaa ttctggctca
    62101 tagaatgaaa aggcttcact aaatttagca taaataccag aggccttagc ttgatattct
    62161 tgatacttgg caactgtcgt atcctgatca tttttcatgc tagcataaac ataaaccttt
    62221 tcaacacgac gagccagctc caaatgcagc tctgtgatat ctaagagact gctgcttgaa
    62281 tccaacaaat gcccagcctg ctgccttgca gcctcaattg ctgccagcag actatctgcc
    62341 tctgtctccc aagctgcgtc tgttgcaaaa atagtgctta aatcccaagt gtacttttcc
    62401 tctagatgac tacgattatc tgtcatacgg acctcctaag tttctattac taatcatttt
    62461 aacataatat gctggtgaaa aaagcttttg cacctcttta tttgctgctt ttgcgtaata
    62521 tttttcaaag caatcgtaat agtggctcaa atcctcatga atctggcaaa agccagctga
    62581 gcaagcaatc ggcttaacct gtggataata agcctctagg ggcctatcaa gcaggttatc
    62641 cccagctaga taagcctctt cttgcttttt caaccatttg ctatcttttg ctagtaaggc
    62701 tttttgaatc cttctcagca agtgcttatc catctggagc tgataggctg acaggccttt
    62761 tctttggtaa ggcagccgca aaaaggccaa caaatcatca tctaaggaac aggtctttac
    62821 tagatagctg accttaccaa ataaatcctc atgaatcata
//
LOCUS       DARYJX010000007        58400 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYJX010000007 DARYJX010000000
VERSION     DARYJX010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58400
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..600)
                     /locus_tag="TU257_000413"
     CDS             complement(<1..600)
                     /locus_tag="TU257_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0833455.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TU257_000414"
     CDS             1005..1649
                     /locus_tag="TU257_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833456.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TU257_000415"
     CDS             1654..2403
                     /locus_tag="TU257_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0833457.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU257_000416"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU257_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0833458.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU257_000417"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU257_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL0833459.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TU257_000418"
     CDS             3125..3955
                     /locus_tag="TU257_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833460.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TU257_000419"
     CDS             4015..5295
                     /locus_tag="TU257_000419"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL0833461.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TU257_000420"
     CDS             complement(5500..6792)
                     /locus_tag="TU257_000420"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0833462.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TU257_000421"
     CDS             complement(6782..7498)
                     /locus_tag="TU257_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0833463.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TU257_000422"
     CDS             7752..7976
                     /locus_tag="TU257_000422"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833464.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TU257_000423"
     CDS             7987..8907
                     /locus_tag="TU257_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833465.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TU257_000424"
     CDS             8894..9634
                     /locus_tag="TU257_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833466.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TU257_000425"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TU257_000425"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL0833467.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TU257_000426"
     CDS             11532..12479
                     /locus_tag="TU257_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0833468.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TU257_000427"
     CDS             12495..13376
                     /locus_tag="TU257_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0833469.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TU257_000428"
     CDS             13520..14434
                     /locus_tag="TU257_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0833470.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TU257_000429"
     CDS             14606..16000
                     /locus_tag="TU257_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0833471.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TU257_000430"
     CDS             complement(16048..17739)
                     /locus_tag="TU257_000430"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL0833472.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TU257_000431"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TU257_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0833473.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TU257_000432"
     CDS             18455..18805
                     /locus_tag="TU257_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0833474.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TU257_000433"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TU257_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL0833475.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TU257_000434"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TU257_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL0833476.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TU257_000435"
     CDS             23487..24710
                     /locus_tag="TU257_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0833477.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TU257_000436"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TU257_000436"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL0833478.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TU257_000437"
     CDS             25318..25869
                     /locus_tag="TU257_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL0833479.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..27150)
                     /locus_tag="TU257_000438"
     CDS             complement(26305..27150)
                     /locus_tag="TU257_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0833480.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27447..28019
                     /locus_tag="TU257_000439"
     CDS             27447..28019
                     /locus_tag="TU257_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0833481.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            28013..28303
                     /locus_tag="TU257_000440"
     CDS             28013..28303
                     /locus_tag="TU257_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833482.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            28989..30260
                     /locus_tag="TU257_000441"
     CDS             28989..30260
                     /locus_tag="TU257_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL0833483.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            30354..31490
                     /gene="recA"
                     /locus_tag="TU257_000442"
     CDS             30354..31490
                     /gene="recA"
                     /locus_tag="TU257_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL0833484.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            31866..32264
                     /gene="spx"
                     /locus_tag="TU257_000443"
     CDS             31866..32264
                     /gene="spx"
                     /locus_tag="TU257_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL0833485.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            32377..32646
                     /locus_tag="TU257_000444"
     CDS             32377..32646
                     /locus_tag="TU257_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL0833486.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            32643..33062
                     /gene="ruvX"
                     /locus_tag="TU257_000445"
     CDS             32643..33062
                     /gene="ruvX"
                     /locus_tag="TU257_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL0833487.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            33072..33371
                     /locus_tag="TU257_000446"
     CDS             33072..33371
                     /locus_tag="TU257_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL0833488.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            33919..35478
                     /locus_tag="TU257_000447"
     CDS             33919..35478
                     /locus_tag="TU257_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL0833489.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            35575..37773
                     /gene="nrdD"
                     /locus_tag="TU257_000448"
     CDS             35575..37773
                     /gene="nrdD"
                     /locus_tag="TU257_000448"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL0833490.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            37879..38025
                     /locus_tag="TU257_000449"
     CDS             37879..38025
                     /locus_tag="TU257_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833491.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            38053..38988
                     /locus_tag="TU257_000450"
     CDS             38053..38988
                     /locus_tag="TU257_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0833492.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            39001..39495
                     /locus_tag="TU257_000451"
     CDS             39001..39495
                     /locus_tag="TU257_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833493.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            39505..40119
                     /gene="nrdG"
                     /locus_tag="TU257_000452"
     CDS             39505..40119
                     /gene="nrdG"
                     /locus_tag="TU257_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL0833494.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TU257_000453"
     CDS             complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TU257_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL0833495.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            41750..41953
                     /locus_tag="TU257_000454"
     CDS             41750..41953
                     /locus_tag="TU257_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0833496.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            41955..42408
                     /locus_tag="TU257_000455"
                     /pseudo
     CDS             41955..42408
                     /locus_tag="TU257_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            42418..43092
                     /locus_tag="TU257_000456"
     CDS             42418..43092
                     /locus_tag="TU257_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0833497.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            43122..43559
                     /locus_tag="TU257_000457"
     CDS             43122..43559
                     /locus_tag="TU257_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833498.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(43782..44555)
                     /locus_tag="TU257_000458"
     CDS             complement(43782..44555)
                     /locus_tag="TU257_000458"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL0833499.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(44639..45706)
                     /gene="pepA"
                     /locus_tag="TU257_000459"
     CDS             complement(44639..45706)
                     /gene="pepA"
                     /locus_tag="TU257_000459"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL0833500.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNLGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            46051..46398
                     /locus_tag="TU257_000460"
     CDS             46051..46398
                     /locus_tag="TU257_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL0833501.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            46395..46712
                     /locus_tag="TU257_000461"
     CDS             46395..46712
                     /locus_tag="TU257_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL0833502.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            46727..47353
                     /locus_tag="TU257_000462"
     CDS             46727..47353
                     /locus_tag="TU257_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL0833503.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(47656..48369)
                     /locus_tag="TU257_000463"
     CDS             complement(47656..48369)
                     /locus_tag="TU257_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0833504.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            48481..48876
                     /locus_tag="TU257_000464"
     CDS             48481..48876
                     /locus_tag="TU257_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0833505.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            49323..50297
                     /locus_tag="TU257_000465"
     CDS             49323..50297
                     /locus_tag="TU257_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0833506.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            50315..51277
                     /locus_tag="TU257_000466"
     CDS             50315..51277
                     /locus_tag="TU257_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0833507.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            51392..52276
                     /locus_tag="TU257_000467"
     CDS             51392..52276
                     /locus_tag="TU257_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833508.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            52285..53088
                     /locus_tag="TU257_000468"
     CDS             52285..53088
                     /locus_tag="TU257_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0833509.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(53187..54191)
                     /locus_tag="TU257_000469"
     CDS             complement(53187..54191)
                     /locus_tag="TU257_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833510.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(54477..55118)
                     /locus_tag="TU257_000470"
                     /pseudo
     CDS             complement(54477..55118)
                     /locus_tag="TU257_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(55139..56116)
                     /gene="dusB"
                     /locus_tag="TU257_000471"
     CDS             complement(55139..56116)
                     /gene="dusB"
                     /locus_tag="TU257_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL0833511.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(56103..56975)
                     /gene="hslO"
                     /locus_tag="TU257_000472"
     CDS             complement(56103..56975)
                     /gene="hslO"
                     /locus_tag="TU257_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL0833512.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(57225..>58400)
                     /locus_tag="TU257_000473"
     CDS             complement(57225..>58400)
                     /locus_tag="TU257_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL0833513.1"
                     /translation="LHNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNT
                     ELTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELV
                     GYISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLE
                     LENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLS
                     IIYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTN
                     KSVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYIL
                     KEKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        16831 a        10318 c        13185 g        18066 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacgcat aaaacacctc taaaatgtta ctaaatgcta
    27181 caaaaaaata aaatctacaa tagtatttta taatagcatt tagaaagagt aaaggaggaa
    27241 aatttatgag gagacatcta aaggttgtat tattacttgc agcactattg gcatttattg
    27301 taaatgaggg taattttcca tggtggcctt ggggaccata gtacttaact gattactgtt
    27361 atgttgttgc cattagacta tctagattaa tcaaagagta aaatacaagt agcttagtga
    27421 aagacatttt aagaggagaa aagcatatga agaaacgttt agcatttata ttagttgctt
    27481 ttggtatttt gggatttagt ttaggaaatg aagttttagc tgcagatact gcacctgcaa
    27541 gtgcaactat ggcaacagat agtgatgtga gtttttacaa tggagaactg ttgaaaaaat
    27601 atttggtcca aagtggtgat agattgtatt ttgattatga caaagctatt caagataaag
    27661 tttctgatgg tgtaatagat atgggattcc ttgttgagac aattagtgag gactattcac
    27721 aacaaacgtt tacctctcga aagtatttca aggcaggatg gcagctttat ggtaattatt
    27781 gtggacctgg ccataacgga aatcatttta ctttacctgt tattgatgtt ttagatcaag
    27841 gctgtcaaaa tcatgacagt tgttatcgat ggggagctgg gattggtgca aattgtgaat
    27901 gcaatcgtca gttagtaaat tacattaaag tatatcgacg gtggatgcca gctcatgcct
    27961 tgggggttgc tgatgctatt agagtatatt ttgaaacggt aggtgctatt ggatgttaac
    28021 cttaaaaaat attatcaatc gatactacat gtattatgta ttccttattg ttgtgatctg
    28081 gattgggatg ttttttgtac gatgggatac tactgtggct ggtgtattac tctatccact
    28141 gattatgaag caggtattta tcgtactagg agtagttgcg atgataatgg ccattatttc
    28201 tagaaaaatt gttcttggaa tttttggttt actatgctgt gctgcttttt ggattaatct
    28261 tttcttagct ttctatctat tacctggact tttgggaaat tagcgattaa actgtttttg
    28321 atgttttgaa gatgagaaac agattgtttt tctgtaaggc ttcctgttac ttctcaaatg
    28381 ctttggagta tctctttatc atttgttcac tgttgacaac gttaaaaaga ttattccaaa
    28441 catgggaatt gctgcttcag ggtattcctt gttaatattg gattgattag ttgttattta
    28501 tgcaaaatcc ttagagcatt gctttctcat tcttggttca tttgaataaa atgtaactaa
    28561 aaaaactttg taatcaattc aaattgtcac aagtataaaa gtaaaaaagc gactttgtta
    28621 gtgatctgat attcggaagt cctatcattg ctcgcttttt gttttttgag gttgattttt
    28681 attccgaaat tgttgtgaat aagtgcaatt ttaagctaag aattacctaa aatcttttga
    28741 agattactgc ttagcttcta atacctattt atcggtgtgt tgataattgg agagatagcg
    28801 ggattgtcat atgaaataaa ttttagaaaa tttaaacaag ttattctgat tattattatt
    28861 tcaacataag tctttatttg attatcattg aaaaccatta attcatctaa aattatttca
    28921 atgcttcatg gatgattctt tttttgttaa aatgagattg aatgtcgaat agataagtag
    28981 gtgggaaaat gaaagctgaa ctcattgcgg tgggaaccga gattctgact ggtcagattg
    29041 tgaataccaa tgctcaattt ttatcagaaa aaatggcgga gcttggtatt gatgtttatt
    29101 ttcaaacagc tgtaggagat aatgaagagc gtttgctttc tgttattgat attgctagcc
    29161 agcgaagtga tttagtgatt ttatgtggtg gtcttggtcc aacagatgat gatctaacga
    29221 agcagacctt agctaagtat ctgggaaaag ctttggtctt tgatgagcag gcaggtcaaa
    29281 aattagatgc tttttttgca catcgtaagc aggctgctag gacaccaaat aaccaacgtc
    29341 aggcgcagct gattgaaggc tctattgctt tgcaaaatca aacaggactt gcagtaggtg
    29401 ggttaataac tgtagatagg gtaacctatg ttgtcttacc agggcctcca agtgagctaa
    29461 agcctatggt aaaaaatgag ctggtgcccc ttctttcagc tagtcatgcc agtctatatt
    29521 caagagtgct gcgttttttt ggcattggtg aaagtcaact ggtgactgct ctggaggatt
    29581 tgattaagca tcaaacagat cctactattg ctccttatgc aaagaccggc gaggtaacac
    29641 tgcgactatc cacaaaggct gacaaccaag cattagctga tgaaaggctg aatcgactag
    29701 aggcgcagct cttatccata agaactgtag ataatcaacc cttacggcgt ttgctttatg
    29761 gctatgggga ggataattcc ttggcgcgtg agacctttga gctattgaag cgaagtggta
    29821 agacgataac agcagctgaa agcttaacag caggactgtt tcaagctcag ttaactgatt
    29881 ttgcgggagc ttcacaggtg tttaacggtg gctttatcac ctacagcatt gaagaaaaag
    29941 caagaatgct tggcattcca ttgggtgagc tacaaaggca tggtgttgtg agctctttta
    30001 cagctgagca aatggctgca caggcacgct gcttgaccaa ttcagatatc ggtattggtc
    30061 taacaggtgt tgctggtcca gaggcactcg agggacagcc agcaggaaca gttttcattg
    30121 gccttgccac taagaataag gtagaatctc ttaaagttgt tataggaggc cgtagccgtt
    30181 tggacgtgcg gtatattgct gccctatatg cttttaatat ggttcgtaaa actttattaa
    30241 aatcagagaa tttgctataa ttaggatagt gtattttagg aaattagtaa ctagacagat
    30301 gtgaggttat gctgtttatt gcttgctagt cagcctaaat agaggagaaa atattggcaa
    30361 aaaaagttaa aaaaaatgaa gaaatcacca aaaaatttgg tgatgaacgt cgtaaagcac
    30421 ttgatgatgc gttaaagaac atcgaaaaag attttggtaa gggtgcggtt atgcgccttg
    30481 gtgagcgtgc agagcaaaag gttcaggtga tgagttcagg cagtcttgct ttagacattg
    30541 cgcttggagc aggtggctat cctaaagggc gtattattga aatctatgga ccagagtctt
    30601 ctggtaaaac aacagttgcc ctgcatgcag tagcgcaggc tcaaaaagaa ggtggtattg
    30661 cagccttcat tgatgcggag catgccttgg accctgctta tgctgcggcg ctgggtgtta
    30721 atattgatga gctgcttttg tcacagccgg attctggtga gcaaggactt gagatagcag
    30781 gtaaactgat tgattctggt gctgttgatt tggttgttgt cgactctgtt gcagctctag
    30841 tgcctcgtgc tgagattgat ggtgatattg gtgataacca tgttggcttg caggctcgta
    30901 tgatgagtca ggcgatgcgt aagctttcag cctcaatcaa taaaaccaag acaattgcga
    30961 tctttattaa ccagctgcgt gaaaaggtag gggttatgtt tggtaatcca gagacgacac
    31021 caggtggtcg tgctttgaaa ttctatgcct ctgtccgtct ggatgttcgt ggaacaacac
    31081 aaataaaagg aactggagat caaaaagaca gtagtattgg taaggaaacc aagattaagg
    31141 ttgttaagaa taaggttgct ccgccattta aggtggctga ggttgaaatc atgtatggag
    31201 aaggcatctc acgtacaggt gagctgatta aaattgcttc agatttagac attattcaaa
    31261 aggctggtgc ttggttctct tataacggtg aaaaaattgg tcagggctct gaaaatgcca
    31321 agagatattt ggctgatcac ccagagctgt ttgatgagat tgaccataag gtgcgtgtta
    31381 aatttggctt gcttgaagat actgaggaaa gtgcagctgc agatacagtt gcagccaaag
    31441 cagatgagtt ggttttagag ctagacgatg ccattgaaat tgaggattag tgcttagtat
    31501 tagattttca gataaaggtg ctaaaaaggg cttaacagcg atcgtcaagc cctttttagc
    31561 ttgtgtttaa tcaagctctg tattggtctg ctcaggagct aggctgtacg cttggataat
    31621 ttgttagctg agtttatgtt ttctttaggg attaactgtt aagctataaa agccctagaa
    31681 aaaagggact tcctacagac aagatagtgg catagtaagc ttgcttgcaa ctagctcaat
    31741 ataggatttt ggccttggtt aaagggatca taaaagaaaa ctaaaaaata ggtccaaaga
    31801 ccgatattga ttagaaaaaa actatgctac aatagaggta tcacgagata gaaagtgaga
    31861 acaacatgat aaaaatttac acgatttcaa gttgtacgag ctgtaaaaag gctaaaacct
    31921 ggctgaatgc ccataagctc ccatataaag aacagaattt aggaaaagaa cctctttcaa
    31981 gagaagaaat tttagctatt ttatcaaaga ctgaaaacgg tgtggagagt attgtctctt
    32041 ctaaaaatcg ttatgccaaa gccttaaatt gtgatattga cgagttaagc gtaaatgagg
    32101 ttattgattt gattcaggat aatccccgta ttttaaaaag tccgattctt atcgatgaca
    32161 agcgtcttca ggtgggctac aaggaagacg atattcgtgc ctttttacct cgttctattc
    32221 gtaatattga aaatgcagag gcgcgtttac gcgctgcctt ataaaaagct ctgtcagagc
    32281 tttttttaat atcctaacaa atctgaattc ttgtttattc aataaaaata agctataata
    32341 gagcgtagca cttaaagtta gaaagaaggt gtaagtatgg gatttacaga tgaaacagtc
    32401 cgctttaatt tagacgatgg tgataaaaag cagattagcg aaacgctgac ggcagtttat
    32461 cattcactag atgaaaaagg ctacaatccg attaatcaaa ttgtaggtta tgtactaagc
    32521 ggggacccag cttatgttcc tcgttacaat gatgctcgca accaaattcg taaatatgag
    32581 cgcgatgaga tcgtagaaga gcttgttcgc tattatttgc aaggaaatgg aatagatatt
    32641 agatgagaat aatgggactt gatgtcggtt ctaagaccgt cggtgtggca attagtgatc
    32701 cacttggttt tactgcccaa ggactagaga ttattaggat caatgaagat aaacaggatt
    32761 ttggctttga tagattagct gagcttgtta agcaatatca ggttgatcga tttgtcattg
    32821 gcttgccaaa gaatatgaat aacactagtg gcccacgtgt tgaagcaagt aaggcttatg
    32881 gagataagat tgaggagctc tttcacattc cggtttctta tcaagatgag cgcttgacaa
    32941 ctgttgaggc agagcgtatg ttgattgagc aggcagacat cagtcgtggt aaacgtaaaa
    33001 aagtaatcga taagctggct gcgcagctga ttttacagaa ttatttagat tgtaactatt
    33061 aaggagaaca gatgacacat aatcatgatc acgaacacga agtcattaca cttgtcgatg
    33121 agcaaggaaa tgaagcattg tttgaaattt tattaaccat cgatggacgt gaagaattcg
    33181 gtaaaaacta tgttttacta gttcctgctg gttcgcaaga ggatgaatca ggagaggttg
    33241 agattcaggc ctattcattt acagaaaatg aagacggaac agagggtgat ttacagccaa
    33301 ttccagagga ttcagacgct gagtgggata tgattgagga agtctttaat agcttcttag
    33361 acgaagagta acaacctgag gcattagctt taaaataata aatagcctag aatcttggtg
    33421 ctagcagcat gggttttagg ctatttttat ggtttatcag acagtaggag tgatagctat
    33481 ttctatgacc tctaaatagc ctactgttaa gagtgttttt agggtcttgt agatgttgca
    33541 atagcctgta atttcgttga agttacttgc tgttgtcttt tttagtttaa gccttaacaa
    33601 agcttatagg aaatgactca acttagcaca gcataagccg cttattttga taagtaaaga
    33661 aatagccaat agctactttt agcttaaagc tgatcattac cagtaccctt agcttttctg
    33721 ggtattattt cgaataatct taatgggggt gattttatca aaagactcag tcaagaagaa
    33781 aaaagctttc taaagcatta taggctaaag acactgcacc gctttaaaga gctgctgact
    33841 tatgccagca tttgtcataa attgactaaa taatagattt tgctatactt gtaatatgac
    33901 atgtcaagga gaaacacatt gagtcaatta catcaagaag ttatgctgga aaaggtcaat
    33961 tatttggtga aagaccaccc atcgtcacat acgactaagt atgacatgaa ggtccctagt
    34021 ttatataaat tttatatctt tttctttagc atcatagcga gcttgcttac ggttgcggtt
    34081 cctttttttg cagatactgc aaatagcgtt cagtcacaaa atttatacat cggaatgatg
    34141 ttgactaaag gtcagattcc atatagtgac ttgtttacaa caggaggctt tctgtttttt
    34201 gtgctcatag ctttgagcta tcacttggga acaacggtat ggttggtact tgttcaagcg
    34261 ctgtgctttt atttgacagg tgtttatttc tataaattaa tccattatgt gacaggtatt
    34321 cagaaggtgg ctttaggttt tacagctatc tattacctat tgtctattag tcttggattt
    34381 ggtggcttat atgcgatcca gcttgccctg ccttttgtct tggtatcgct ttggttttta
    34441 accaagtatt ttgctggctt ggtaaaggac gaggccttta ttctctttgg ctttgcagcg
    34501 gcaatagcca tgctaattga gcctaggacg cttctttttt ggctgcttgc ctgcattgcg
    34561 attattgctt ataatgtgtc tcaaaagcat ttcgctcgag gcttttatca gctgttagca
    34621 gctatttttg gaatgctttt ggtgttttat acagcaggct attttatcct caatttacag
    34681 attttgagtc cttatttgga gcaggcgctt gtttatccgt ttagttattt tgtgacaggt
    34741 gatttatcgc tgattctcgg tttaacagtc caattaggac ttgttcttgg cttgggactg
    34801 ttaacggggc tgctgacgtt tatgaagcag cctaagctag agtctgatct tgctatgaaa
    34861 tggctactag tctttgttgt gtttagctat gctggtattg cggctatatc gcatgatttt
    34921 catacttatc acctactgcc tttactgcct tatgctttga tcttgctatc aagctctgtt
    34981 ggccgacaat atgaggcagg acttaggatg gttagtcatc gtcgtcgtaa ggggaaaaat
    35041 ggtgcgagac gggttattgc tatttatcta aataagcatt tctacgtgcc agcaatcata
    35101 atgctaggag cggtttttgg cacagcttat cagtatgtga ccagctctgc tattaatcaa
    35161 gagcgttctc agattgctca ctatctaaga cagaggctaa cggaggacca acccatctat
    35221 gtatgggacg atacgtcaaa aatttacctg gaaacgcagg ccaagtcagc ttcacagttt
    35281 gcctcaccct ttgttaatct gaaaaaagag agtcatcaac agatgttaga ggatgagcta
    35341 ctacagaata aggcagtcta tattgtggtc aacaagcaaa aagcattacc aaaggcagtc
    35401 aagaaaatag tgacagctaa ttataaaatt gacagaaaga ttgatgttaa gggctttagc
    35461 ctatatcaga aaaaataaat aaaatcaata tattgtgttg gtataaaaaa acttaacaca
    35521 atatattgat ttttttgtgt ggcgtgatat aatagtcgag taaggagata ggacatgata
    35581 acattagaaa aagacaaagt tattgttcag ccagctatta aggttattaa aagagatgga
    35641 cgcttggtta attttgatgc aacaaagatc tacagtgcgc tgttaaaagc aagcatgaag
    35701 gtaacacgca tgtcaccgct cgttgaagca aagctagaag ctatttctga acgcgttatt
    35761 gcagaaatta tcgagcgatt tcctacaaat attaaaattt atgaaattca aaatattgtt
    35821 gagcatgagc tattagccgc taatgaatat gctattgcta aggaatacat caattataga
    35881 acccagcgtg actttgcccg ctcgcaggcg acagatatta atttttctat tgataagctc
    35941 attcacaagg atcagacagt agtcaatgag aatgccaata aggatagtga tgttttcaat
    36001 acccagcgcg atttgacagc tgggattgtt ggtaagtcta tcggtttgaa gctgctgcca
    36061 gcgcatgttg ctaatgccca ccaaaaaggt gatattcact accatgattt agattatagt
    36121 ccttatacgc caatgacaaa ctgttgtttg attgatttta agggaatgct ggcaaatggc
    36181 tttaaaattg ggaacgctga ggttgaaagt cctaagtcta ttcaaacagc aacagctcaa
    36241 atttcacaaa tcattgctaa tgtggcctcc agtcagtacg gtggctgtac agccgatcgt
    36301 attgatgagt ttttggcacc atatgctgag ctaaatttca aaaagcatat ggctgacgct
    36361 gaaaaatggg ttattgagga gctgcgggaa agttacgcct ttgaaaaaac aaaaaaagac
    36421 atttatgatg ccatgcagtc tctagagtat gagatcaaca cgttatttac ctcaaacggt
    36481 cagaccccct ttacctcatt gggatttggt ctagggacct cttggtttga gcgtgagatt
    36541 caaaaggcta ttttaacgat tagaattaat ggcttaggca gcgagcaccg tacggcaatc
    36601 ttccctaagc tcatctttac ggtcaagcgt gggctcaatt tagagccaga ctcaccaaac
    36661 tatgatatta agaccttagc cttggaatgt gccacaaagc gcatgtatcc agatatgtta
    36721 tcttatgata agattattga gctgacagga tcctttaagt caccaatggg ctgtcgctct
    36781 ttccttcaag gctggaagga tgaacagggg caagatgtta cctcagggcg tatgaacctt
    36841 ggggttgtaa ccatgaattt acctcgtatt gctatggaat caaatggcga tatggataaa
    36901 ttctgggagc tgtttaacga acgattacac atttgtaagg acgctcttgt ttatcgtgta
    36961 gagcgcgtta aggaggcaac gccagccaat gctcctattc tttaccaata tggagccttt
    37021 ggcaagcggc tagctaagac tggcaatgtt gatgagctct ttaacaatcg ccgcgcaact
    37081 gtatcattgg gttacattgg cttatatgag gtagcaaccg tattttacgg tgggcaatgg
    37141 gagcacaacc aagaggccaa agactttaca atcactattg ttaaggaaat gaaaaaggct
    37201 tgcgagactt ggtcagatga atatggctat catttctctg tttactcaac accatcagaa
    37261 agcttgacag atcgtttttg ccgcctagat actgacaaat ttggcgttgt tgctgatatt
    37321 acagataaag aatactatac taattcattc cactatgatg ttcgtaaaaa tccaacacct
    37381 tttgagaagc tagattttga aaaggcttat ccagcagccg gtgcttcagg tggctttatc
    37441 cattactgtg agtaccctgt tttgcagcaa aatcccaagg ccttggaagc tgtttgggac
    37501 tatgcttatg atcgtgtggg ctacctaggc acaaatacgc caattgataa gtgctatgaa
    37561 tgccattttg agggagattt caccccaaca gagcgaggct ttacttgtcc aaattgtgga
    37621 aacaatgacc ctaagacagt agatgtggtt aaaagaacct gtggttattt aggaaaccct
    37681 caggctcgtc caatggtcaa tggtcgtcat aaggaaatct ctgctcgtgt caagcacatg
    37741 aacggatcaa ccatcaagta tccggggata taagccttgg agaataatct cattacacct
    37801 atatcattgt aaaggattgc ttcatgcaag cagtccttta gttatcaaga caggtctgta
    37861 acaaagaaag ggagaaacat gggaaaatac cagttagatt ataagggaat gcagcaagta
    37921 gagaggtttc atgagaaaca ttctgttgca aaaacagaca aaaagtctcg agtacagcag
    37981 cttagagcac aatttttaga aaaagcaaag caatcaaaga aataatggca cactcagtaa
    38041 aggcggtgaa gaatgctaga tattggaatt gttgggttag gcgctatttc acaaaaggcc
    38101 tatttaccct atatgcgtca attaagagga atcaattggc atttatctac tagaaatgcg
    38161 ttagtccgcc aggaggtggg tcagcttttt ggttgcgcaa ggctttacag cactgtcaat
    38221 gagttacttg aggctaagtt agatggtgtg tttatccatg cagccactaa ggctcattta
    38281 gagctggcta gtttgttttt acaaaaagga attccagttt acatggataa gcctttgacg
    38341 gaggatttct ttagcacgca ggctctttat caattagcag ataagcacaa tacctttttg
    38401 atggcagact ttaatagacg ctttgcacct ggtgtcaaga agttgtcaac cctgtcaacc
    38461 aaacgtaaag ttgttgttga gaaaaatgat attaatagac caggtgacaa acagtttaag
    38521 ctttttgact tctttataca ccctttagat acagctttat ttttagttga taggaggctt
    38581 gttgcaggct attttcatta tcagctgact gataatgatt tgctaagtca ggttagtgta
    38641 accttaagga cagaacagac tattatttca gcagctatga atctacagtc aggtagcagg
    38701 cgtgaggtga tggaggttca gacacctaaa gagacctatc acctagaaaa tctagagacc
    38761 ttgcgagctt atcgaggggt tgatcaagag atcaagggat ttagtgcttg ggatactacc
    38821 ttatctaaac gaggctttga ggctattgtg gattcttttt tacaggctgt caaggatggt
    38881 gttaaccctg tcaagccaga gacaagtctg ttgagtcact ggatttgtca ccaaatttgt
    38941 caatctcatg aagctgatgg catattagat gtttctcttc ccttataaag gagtgataat
    39001 atgaagctac gaagacctaa aaagcaagat gaagcgtctg ttttagaaat gatggcagag
    39061 tttgaagact atcagtctcc tcatgatggt ggtttttgga acgctgagca ttttgattat
    39121 gaaaaatggt tggaatctaa tgctctgatg gaggctggct tagctatccc tgagaattgg
    39181 gtgcctgcca tacagctcgt tgcctttgct gatcaacagg ctattggatt tgtcaatgta
    39241 cgcttgagat taaacgaaca gctactggta aaaggtgggc atattggtta ttctgttaga
    39301 cctagccagc gtggaaaggg ctatgcaaag ctgatgctaa aggaagcctt gcagcttgct
    39361 cgtcaaaagg gcattcgtga ggttttagtg acttgtcatt gcagcaatag tgctagtcgg
    39421 tctgttattt tagctaatgg tggtcagctg aaggattgca ataagggtat tgaacgctat
    39481 tggataaaag cataagaggc aataatgaag gaaaactgtt ggaattctcc caaaccaaaa
    39541 gaatggacat cagaggcatt aagccaagga cgcgttattg attataaggc atttaatttt
    39601 gtagatgggg agggagtgcg aaactcactt tatgtttcag gctgcatgtt ccattgtaag
    39661 ggctgctata acgcagcaac ctggtctttt aaggcgggta ttccttatac gaaagagctt
    39721 gaggagcaaa ttatgactga tcttgcaaag ccctatgttc aaggtttgac acttttgggc
    39781 ggtgagccct ttttgaatac gggaatattg attcctttga ttaagcgtat cagaaaagag
    39841 ctgccagaaa aggatatttg gtcttggaca ggctatacct gggaggaaat gatggaagaa
    39901 acccaggata agctagagct gttaagcatg attgatattt tagttgatgg ccgctttgat
    39961 atcaccaaaa agaatctgat gctgcaattt cgtggatcca gtaatcagcg tatcatcgat
    40021 gttaaaaagt cactggctgc tggagaggtg gttatttggg ataagctaaa tgatggtgat
    40081 cagtcctttg agcaaatgag ccgcgatgat ttgatttagt agagacttat caacatcact
    40141 agacttgaaa gctaataatg aaagcatgat tttaggctcc tgtggtcttg cttaaccaat
    40201 ctaataaggg gttttcccca cattatcctc atacttatcc acaggttgtg aataacctgt
    40261 tggtttgtgg ataaaaaaga gaattaaggg gttctttaat tctctaggcc tgaaaaaggg
    40321 ttctttttga tgttttttct taaaagaaag agaggcaagt gacctctctt gaaatagtat
    40381 acttaggctt taagcctagc tttcaatatc tctgaatgtc tgattttctt aggagtcagg
    40441 cattttttaa tggcgatggg aagtacggct tgtgggtcgc tttgtgtgct aagaggcttt
    40501 ctgagctgct atatgtcaat gattggtgat gtgacagctg aggcttgttc acattctgaa
    40561 agcactgatg tttttcctag ctttcttttt tgatgtagta gtaattagtt tcggttgata
    40621 gctcctcatt atagcaaaag ccagcaaagc tcagctgctt aagtgcttcc ttggtttgga
    40681 cattgttttc tagacaggct gttagaaagg ctcctcgagc tttttttgaa atggttgaat
    40741 gcgtcttgag ctgtcctgat ctttcctcca taaatttggg acttatccac agtttttgat
    40801 attcctttga aaaaacatct ctaaactcgt tggataacag agaaatgatt tgcttgtgat
    40861 ctttagcaaa ctgatcgtag atagggcgcc aataatgctt aaggctttgc ccattgatgg
    40921 ttactttagt gtgaaaatca tgccggtgct ctgcgatttt ctcatcagta gggataatgc
    40981 cataaaaaga cgaggtaatg tagacctgct ttgagaggta gtcttgctgg tctttagaga
    41041 gattgtcgcg cttgagatga cggtacatga gcccattaaa gagctgataa gcaggataag
    41101 cagaactctg cccttgagct atggccttta gtctcttggc ttccttgctt gctgcttcta
    41161 tacggatgct gtaggccctt gctagctcct ctagggatag ttcagccata gcctctaata
    41221 tgggcaggct tttttgggga agctgatgtg gatagcaagg tggaactggt ttcatttctt
    41281 tagctgttgg aattaaaaaa gttaacataa gtttattgta gtaaaggcgg caaccttctg
    41341 tcaagagtgg gatacatttg gtggttatgt catatgaaac taatttttat attttttaca
    41401 ttttgattag tttttaaaaa tatagtgatt tagtgttgca taacctctct aagtatgtta
    41461 atatatactt aagtctgttt gataaacaga agctcaggtc aagtgagtgt tccacttaca
    41521 ataacgcagt tgatgatggg gagactcaga ctcagactca gagtcaagga aaagaaatat
    41581 agtcttgtag gattacctac agggcttttt tctattttga attgagagat caatataagg
    41641 tgatgtgctg ttttttatta ccttaaacat ttggatattg gctattgaca aaaagtgtaa
    41701 aggaaactat actatatgtg taaagttaac ttgacatatt ggaggaacca tggaaaatcg
    41761 gatacaagaa ctccgtaagt cacgagggat tagtcaagct gatttggcag atatgatgtg
    41821 tgtcactagg caaaccatta tctccttaga gaaaggacgc tataatgcgt cattagagct
    41881 ggcctataaa ttagcgacat ttttcaatct gactatagaa gacgttttct tgtttgaaga
    41941 gaagggagaa tgagatgata tttagtgatt taagcgtcct gctgactcaa aaaagccagc
    42001 tagcctatgc caaaaggctg aagtatatgg gctttttcgc tctctgttta ggcggtttgt
    42061 ttttgttgct ggcctttgac gtgagactga cgagctttgc tcagggaatg ctggtagggc
    42121 ttggtagtgg tagcttatta ttaggtgttc gtgctttttc agattgcctt taatcctcaa
    42181 aggctgagag cctcttatat taaggcttat gatgagcgtc atcaggtagt tatcaagcta
    42241 gctgctgtat caaccttaat cttattagtg gtgttgatta ttggctgttt gtgcttgaat
    42301 gttttttgga gtttggtttt tggctttaga gtatttttag agatttgtct gtatacgatc
    42361 ttgcttggtt ttttaggcat caagctattg ttagagcata tgatttagga ggcttcaatg
    42421 gaaacaaaac attcagcagt aaaggtcatc atcagtaaat taaaatggtt tggcttagct
    42481 cttcttgtgt ttatgcttga gcaggctcca acatttttga taacaaaaga acagccaatg
    42541 tggcagacac ttcttcttgt ggtcattttt cttttgatta gtggaggtac ttattaccta
    42601 gctgtgaagc ttcacattgt gggagatcaa gctattccta agaatgacta tcgggcactt
    42661 tggattggtt tgggagtggt agctgtcttt gttgtcaaga tgattggtgg tattctgttg
    42721 tttttggagc atggtccggg agccaatacg gtcaatcaag ctgccttaga acaggcaggc
    42781 ttatctccga ttcttatggt tacgctagtt gctattgtgg caccaattgt ggaagaaatt
    42841 gcttttcgag ggctgcttta tgggaagctc tttggtgcag agtcttatct gggcttgatt
    42901 tttagcagta tcatgtttgg cttgattcat gtgccaacag attttggcag ttggtttatc
    42961 tatggcggta tggggctggt gttaggcttt gttttccata aaacaaagaa ggtcgaatac
    43021 acgatattga ttcatttttt gaataatgca ctagctgttc ttatcatgct tttgctgcct
    43081 tatcttcagt agtactgctt gagtaatgaa gggggtaatg aatgaaaaat gatcgttgga
    43141 ttgacaaaaa atatcaacgt tgggagaaag tgtataagag acttggtcat tctttactga
    43201 caatcggtgt gttggtaggg acttatggga tttttttgat tattcaaggg aatcatcaaa
    43261 cgggctttct cctttttatc ctggggccta tactattgat tgcgtcatgt ctttgctatt
    43321 atgtgtttac agagccaacg tctttacgag aatatctgat taatagctat gatgagcgta
    43381 accgagctat tcgtcagaaa gcacaggcct actgcttttg tctatttgct tttctctttt
    43441 tgatgcttgc gatattcttt ccaaatatga cgatcaagga gctttttggg tataatcttc
    43501 cgttgattgt tttcaatctg tatgtcatga ttagagcctg ggttagtaaa cacatgtagg
    43561 tcatgttaac acaaaggagt ctagagcaag ggctttgaat gaaactattt ttctaaaaac
    43621 gcaaaaaatc gcgtgcagta acagattagg ccatgttact gcatgcgatt ttgttgtttc
    43681 aaacgtgagc tcagaatgac atatcctttt tagaaagaat aggtatttag ggctgtcttg
    43741 agctagtctt aggtaatgag cttggagctc attggtgatg gttaggatag gtctttagct
    43801 tttttgatcg ttgtgtcaat ggcagagcag acagaatgtg tcaggcctgt tttttcaaga
    43861 tccatcaagc ctgcaatggt tgtgccgccg ggactgcaga tcttatcaat caaatcatgg
    43921 ggactatctg tgctgactag caggttcttg gcgctagcta ggacagtttg actaacgata
    43981 ctaagggcct tgtctttagg cagtccattt ttgactccgg cctttgccat agcttcgatg
    44041 aaaaggtaaa gataagcagg acttgaccct gctagagcag taaaggtatc aaaatccttt
    44101 tcagctattt caaaggttgt tccaaagctg ttggttagct ctttagcagt agctaataaa
    44161 tcagcagtta ctaagtcatt accagtcaaa gcagtggtgc tttggagaat ttgagcattc
    44221 atatttggca tgatacgtag gagtggcaaa tgagagcttg ttaattgagc tagtctgtct
    44281 aaggaaatac cagcagccat tgacatgata ggctgtttga actgtagagg gctaagaaca
    44341 gtctcaaaga gctgtggctt gatccctaga atgatgaagt caacctgatc gatcagctct
    44401 tggtgagatt gggcgtagct taggtgcaat tggccagcaa tttctttaga gcgagctaag
    44461 gatgagcctg agatgattag ctcgtgtggt gtgtgtgtta ggccttgaat gatagcagtt
    44521 gccattttgc caacaccgat aaatccaatt ttcataataa tgttcctaaa aatgaataaa
    44581 ggctcaatag gctagagtgc tcattgaacc ttagattcgc attttagcct tatccttcct
    44641 agtatttctt gattaaatca actgttgagc ggtcaagctt tttgacaatg gcttgcaaaa
    44701 aggcctgtgc ttctacgaaa tcatctaagg cgtacaagct ctgatgtgag tgaatgtagc
    44761 gagcgcagac accgattgtg gttgaaggga taccgccatt tttaaggtga gcagcaccgg
    44821 cgtctgtacc gcctttacca caataatatt ggaaggcaac cccagcctcc tcagcggtgg
    44881 ttaataggaa gtctcgcatg ttcttaagca tgatgtgtcc gggatcgtaa aagcgtagaa
    44941 gggttccatc accaatatgg ccaagattgc cataaatatc accagcaggt gagcaatcaa
    45001 cagcaaagaa aagctcagga tcaaatgtag tggctgacac atgggcacca cgaagcccga
    45061 cttcttcttg gacatttgct ccagcaataa gggtgttgtg aagtgtctgg tcttttaggg
    45121 cttctagcag ctcagtgacc atgagaacac catagcggtt gtcccaggcc tttgagatga
    45181 tattcttttt attggcagtt aaaatggttt cagactgcgg tacaataata tctcctggtg
    45241 tgatgccaaa gctttcggct tcagttttgt ctgtaaagcc accatcaaaa acaatatctg
    45301 aaaccgctgg cagactagca gcaccatttg ccccgcgcag aaaatgggga ggaactgagc
    45361 ctgaaataac aggaatggct tggccagcgc gagtgtataa ggtaaagcgc tgtgagctaa
    45421 caactagtgg attccagccg ccaatttcaa caacccgcag tgttccatca gctttaatct
    45481 cgctcaccat aaagccaacc tcgtccatgt gagccgcaac aagaatgcga ggagcttgat
    45541 ccgccttgct ttcttttatc ccaaatatgc cgccaagtcc atcaacctcc actcggtcaa
    45601 caagcggcgt gatcttagcg cgtaagtaat cccgaacagt gtgctcgtag ccggcgatgc
    45661 cgtctaattc agtaacttct ttaatttttg aaaataaatc aatcatttgt atactccatt
    45721 tgtcatgtaa gattaaaggt atcacgtctg cctctattct atcatttttt agtgaagaat
    45781 gggaaacagc ttgagcatag gaaaagagtt tgggagatta ggtgtgtctt tcttgcttga
    45841 taagctgctt attatcagtt tgattcagat gagataactg ctggtattga tggaatgaaa
    45901 cagctatgca caacagcctt gacaaggatc gacaggcctg agctgtctta tgctatcaat
    45961 tgcacttagg tagagcagta gcctgatatt gatgtgatta gttgctcttg tcaggtggtt
    46021 tattagtatt tcctaaagtg tcagctagtc ttggctgaga ttgttagctt ttgctctagc
    46081 ctattattcc ctttttgtga taaaatgaaa ggtatgaatg gaaaaaagac acgtattgtt
    46141 tcaggattaa ttggactggg tctgctagcc ggcttgggat tgaggcttaa ggaagtctat
    46201 caagaaagag agcgtcagag agtattggtt gaattgcgcg cctttttctc agccttagga
    46261 gagattgagg tcttgtacat caactccttt agctcaaagc gtgatgatgt cactggtggc
    46321 cttgtcatga cagatggtaa gacctatact taccattacc acaaaggaag tattgatttt
    46381 aaagaggatt tgacatgatt attccaacat ctaaggaaga acttgctagg ctaattgaga
    46441 cagagcctag gctggttttg ttttttacag cagattggtg tccggattgc cagtatatct
    46501 atcctgtaat gcctgagcta gaggctgaaa acccggatat gacctttgtc cgccttgatc
    46561 gcgatgattt tatcgattta gcgcaggatt ggcaaatttt tggcattcca agctttcttg
    46621 ttatggaaaa ggggcaggag aagggccgtt tggtcaatag attacgaaaa acaaaggctg
    46681 agattagtga ctttctagca gcctatcact aagaggagaa aatgagatga tttttgcata
    46741 taataaagag caggtcggtg atgttttgat ggtgatacta gaggataaaa aagacatcaa
    46801 gcgacaggtt gagcgtaagg ggagagtagc gcgtgttttt gcagaagaga cagggcaaac
    46861 ccttgcttgg aatatttttg aggcgtcagc cttaatcgct gttgagggaa atgggcaggt
    46921 tttcttgtct gaggaggagt tagcgatttt aaatgcggag cttgctcaag aagggtttac
    46981 tgaacgatta gaggctagcc cagcccctgt ttttgttgtg gggcaaatca ttgagatgat
    47041 tcctcaccca gatagtgatc atttgaatat ctgtcaggta cagattgctc ctgataaggc
    47101 tgtgcaaatc gttgcaggag cacctaatgc tgctgttggg ttaaaaacaa ttgttgcctt
    47161 gccaggtgct atgatgccaa gtggcagcct tatttttcca ggaaagcttc gtgggaagga
    47221 aagctttggt atgatgtgtt ctccacgcga attggccttg ccaaatgctc cacaaaagcg
    47281 tggtattatt gagcttggtg atgctgcagc ggttggtgaa gcctttgatc ctgctaagca
    47341 ttggcagagc tagcaggact tgatcagcat taaaatggtg tttagtcctt cttttgcttg
    47401 gtgaaaagcc tttggacctt gagccatgca gtgctttttg ctggtctgtg actgtcttta
    47461 gcttcaggat cgaagcatta gagtagctgc ttaacttatt gtcagcgctg ttgattgcag
    47521 tagcgctatg cttgtgacaa gtgaaggcaa agcctatcaa tgcccttggc tagggctaaa
    47581 aattgtcttt agagtcactt ttgaggtgag tagctcgcta atttcggtat tgaacggtgc
    47641 ttaggtaccg tttttttaag ctttgctgag tgtgacatgc tgaaaaaagg ccatgtcttt
    47701 atatggcttt tggtcacaga tggctaattc aatcgtccgc aacacttcca gccaatcagg
    47761 cttagcttta acctcatttg gttgaagtcc gtagcatgtc cgcagtccac gatagccttg
    47821 gagcttcaaa tcggtctttc tgagtaagtc atcaatactg taggtctgac ctgctgcaaa
    47881 ggataaactt tcaaaggctt gtccatttag cacattaagt gccttgtcat agtcgtgttc
    47941 aaaaataaca gagtggagaa cttttccgac ttgattgtgc ttgatgagtg atagctgccc
    48001 tttaggcttc aatagacgtt ccatctgagc taggtagatc gcatgctctt ttggggcgat
    48061 atattctaag acattgtggc atatgatcat atcaaaggct tgatcaggca gtttttctag
    48121 cgcttctaat gaacctttta ttttatgaat gctttcttgc ttttgggcaa ataataggtc
    48181 aggatttggc tcaattgcag ttacttcatt ctggacggct aatgcctctg ctgtgatgca
    48241 aaagcctgct ccgaaatcta aaatagtctt gcctgctatg gggcctaatt gggcaaagat
    48301 caaatcatac atgagctttc cccagggcct tgtgagcatg tcttgatagg ctttaagatt
    48361 aatagtcatt atctagtttt cctttcttta gctgctgtga gctattggca ggatttctaa
    48421 acttcacagc ttgtccttat tttaccatgt tttacgaata ataagataag gaggtatgac
    48481 atgtacaata aagtaatctt gataggccgt ttagtggcca agccagaatt aaacaagaca
    48541 ttaacggata agcaggtcgt tcgatttacc ttagcagtta atcgtcggtt taagacgacg
    48601 actggtgagc gtgaggtgga ttttatcaat gctgttgctt ggggaggttt ggctgaaacc
    48661 ttggcttcct atgctagcaa ggggagtctg ctgtcacttg atggcgagct tcgcacacga
    48721 aaatatgaca aggcgggtca gactcatttt gtgacagagg ttttgtgtca ttcttttcaa
    48781 ttgctggaaa gtcgagcgca acgagctata cgtgaaaaca acgctgctaa tgatttgatt
    48841 gatttggctt tagaggagga aaagcttccc ttttaaagac agctgctagc ttactgtcgc
    48901 taagggagtc agacactagc attgtgtatg ctagagatct caacataatc taaaaaatgg
    48961 caacgattct aaaaaaaatc ttgacacgtc ttagaaaaag gtttacaatg tatgacaatt
    49021 aaaatgaaag aaaacaggag gtgctggtat ggtagcagtt agcacagctc agacgatgac
    49081 taagcgttat tactttagct tctttagata gtgtttgtag acatgagcgc atggatacaa
    49141 acacactgaa cgttatgttt gtatctatgg ggctaagggc tatttgagtt gtttgtccac
    49201 atagatgata tctcttctaa gtggacacca tacagcatgt attttgttat ctcatgatac
    49261 ctgtatagga ccatttagat tatctagatg gtcttatttt tatgcaagaa agaggaaatg
    49321 acatgagatt taaacagtta tccttaacag cctttatagg gcttttggca atgctgctaa
    49381 cggcttgtcg acaagaaacc aaccaaacac atcaagctgc tagagttggg attattcaat
    49441 atgctgagca ctcagcccta gatgctgcgc gtgagggttt tattgaggcg cttgagcagg
    49501 gcggctttag agaggggaag aacctgacca ttacaaccaa aaatgcacag ggtgatcagg
    49561 ctaacctgca aacaatggtg gagcagctgg cgggtaagaa cgatttgcag cttgcgatcg
    49621 caacgccggc agcgcaggcg cttttaaata tggactcaga gacaccagct gtatttacag
    49681 cggtaacaga tcctgtctca gcaggtctgg ttgatacatt agctaagcct ggtgggaata
    49741 tgacaggctc tacagatgcg actgatgttg agaatcagat tgatttgttg accaaggcgc
    49801 tgcctcaagc taggacagtt gggattttct acaattcaag cgaggtgaat tcggagatac
    49861 aggctaagaa ggccaagagg gagcttgaga aaaaaggctt aaaggtcctt atgaaaaccg
    49921 taaccactac taatgatgtg cagcaggtta tgacaagctt ggctagtcag gttgacgctg
    49981 tttacctgcc aacagataat acggttgcct caacagctac tactattggg gatattttaa
    50041 aggaggccaa aattccttca atgggaagcg atgctgctta cctgagtgct gttttgttca
    50101 cctcaggtgt tgattaccat gctattggca tgcaggctgg tcagcaggcg gtagatattt
    50161 taaagggtaa aaaaccagca agcattcagg ttgctaagcc tcaaaaggca agcattgctg
    50221 ttaatgatga tatggcaaga cttctgggca ttgaccccga ggtgatcaag gctcttgcaa
    50281 gtaacggagc caactagcgt tttaggagga aggtatgaaa aaaggaagct atttaatact
    50341 gttagtgctt gcaggcttcg ttttggtggc ttgtcgttcg acagctagtc ctcgtaaggt
    50401 taaccaatct catgttaaca tcggtatttt acaatacatg gaacatgatt cgctgacggc
    50461 agctcgtcga ggctttgaag cgcaattaaa ggcagcgggc tatactaagg gagacaagct
    50521 gagccttcat tatcaaaatg cacagggcga ccaagctaat ttacagacga tttcagagca
    50581 gctagtgaag caaaatgatt tgatcttggc gattgcgaca ccggcagcgc aagccttagc
    50641 gaccgtctca tcagatagac caattgtttt tacagcagta acagatccta tctcagcagg
    50701 cttagtggat aggatcaaaa agcctggtgg cttgataaca ggaacaagtg accaggcgcc
    50761 gattgcaaag caaattgact tgttagccca agccttgcca gaggccaaaa ctattggcat
    50821 tttatacaca gctagtgaac gtaatgctga ggtgcaggta aaggaagctg aaacgctact
    50881 gaccaaggtt ggttataggg ttattaaaaa gggaattgcc acttcaaatg atgtgcaaga
    50941 tactgctgca agcttgatga gagcagtaga cgcgcttttt gtaccgacag ataataccgt
    51001 tgcttcaacc atgacaatgc tgggtgagct gtcattggct aataaggttc caattattgg
    51061 tggctcaacg gatatggttg atgcaggtgg gctcttgacc tatggtatcg actacgagag
    51121 ccttggtaga caggctggag aaatggccat taagatttta agaggacagg atccagcaag
    51181 cctagcagtg gagtacccaa aaacagtcaa gctacatatc aatcaagcaa tggcagacaa
    51241 gctagcgatt gatacttcca cattatcagt tgactaaatt gctaggttaa aggctaaatg
    51301 actgatctct agccagctgg ctaaatgaca aagtcttaac cagttagctt agcttactat
    51361 taacgattca tatgacaaaa aaggagaaat catgtcactc attttatcga gcttatcaca
    51421 gggcttattg tggtctatta tggcaattgg tgtttacctg acatttcgta ttttagatat
    51481 tgccgattta actgcagaag gttcctatcc gcttggggca gctatttgtg caacgggtat
    51541 tgtatcaggt gtttctccct tgctggctac gtttttagct tttattggag gcttgctggc
    51601 aggccttgtc tcaggattag ttcacaccaa attaaaaata ccagccttac taacaggaat
    51661 tatcactctg acaggcttgt attctgtgaa tctaaaggtg ctaggaagag ccaatgtggc
    51721 tttattacgt caaagaactt tagttaccca gctctatgat ctaggcttta ccaagcttgc
    51781 agcggtgcta attatgggct ttgtctttgt gaccattgtg atttttttat tagccctgct
    51841 gatgaaaact cagcttggcc tagctctgcg atcgaccgga gacaataatc caatgagtga
    51901 agccaatggt atcaaaacag atcagatgaa aatcatgggg tatatgctat ctaacggttt
    51961 gattgcccta tgtggtgcct tgctttgtca gaataatggc tatgcagatt taaatgctgg
    52021 tgttgggaca attgttattg ggctggcttc gattatcatt gctgaggtga tgattaggca
    52081 gctaagcatt ggctggcgct tagcttccat tgttttaggc tctattgttt atcgcttaat
    52141 tattctagct atcctagcca ttcccggtat ggatgcagat ttggttaagc ttttttcagc
    52201 catgctattg gcagctgttc tttttgtgcc agaattacag caaaggcttc gccttcgaaa
    52261 aacaagttta ggataggaga aatcatgtca gcaatattat caattaaggc tattcacaaa
    52321 acatttgaag caggtacgat taacgaaaat catgtcttga gaggcttatc tttggacatt
    52381 gaggaggggg attttatctc ggttatcggt gggaatggcg ctggaaaatc cacattaatg
    52441 aatactctag caggcactct ggcttttgat cagggcgata ttcttttaga gggaaaatca
    52501 atcaagcatt tatcagccgc taagcgtgcc aaggacatca gtcgagtgtt tcaagaccct
    52561 aagatgggaa ccgcttcacg cttgaccatt gaggaaaata tggctattgc ttaccgccga
    52621 gggaaatcaa gggggctagg ctggggcgtt aaagaaagag agcgccagat ctatcgtcag
    52681 gccttgcagg aattaggcct aaatctggaa aaccgtctta aggccgagac acagttttta
    52741 tcaggagggc aaagacaagc cttgaccctg ttaatggctt ccttagcaaa gcctaaggtc
    52801 ttgttgctag atgagcatac cgcagctctt gatcctaaga ccagtacaat ggtaatggct
    52861 ttgacaaagc agcttgttga gacacatggc ttgacaaccc tgatgattac ccataatttg
    52921 gaaaatgcta ttgcttatgg taatcgtctg gtcatgctcc atcaaggtaa tattgtggtg
    52981 gatattaaga gagaagagaa ggccaagctg acggttgacc acttgatggc actctttcac
    53041 caaaatagtg gtcatacgct ccttgatgat gcacttgttt tgggataggc taggtgaggg
    53101 ttagctctgt tttcaaatag cagccataat gaaaaggctt aaagccaacg cttctagaaa
    53161 cgctagctca agccttgtta taatacttag gagatttttc taagagtgat aaagccatga
    53221 tgacgtctat tgtagtcaaa ggatttgttt cggatgcgat aagcctcatt ttccacaatt
    53281 tcaattgcct tattcagctg ctgaatggta atcgcctcat caatctcatg aaaagcagtg
    53341 ctataataat cctcactaac acgttgattg cggtctttat aggtattttt atgctctgtt
    53401 aaaatggcct tagcctcagc acgttttgca atggtatcta taataccttg accatatgct
    53461 ctagcctctt gaaggattga cagcatattg tctagagaat atgcgtttgc taagcggctg
    53521 acaaagctat cagcgacctc aggacttaaa ttaataccat ctaagtgata aatcatctct
    53581 gggtgtagct ttaggtaata ctgcaattcg cggaacaaaa gcgctggaat tttcgacgaa
    53641 tccctatatg gattgagctg aatctcctga ctatgtagcc tattgataaa atcgtccttg
    53701 aactgcttaa tagcatcgta gtctgatttt tctagctctg ctttaatatt ggctagaatc
    53761 tgggcgtctg aataacgacg atagcttgat agtgaagcag caggcctact agtattggaa
    53821 tttcgagaag cttctgctct tctagtctct ttgcttggtg tttgctgctt atttgactga
    53881 gtctcctgct cggttagtcg tagctcaggg tgtaaacgac taatattgtt aagaaattgg
    53941 ttaacctcat attctgatga aaactttagc ctaggtctgg ccttgacctt ctcaatagcc
    54001 ttgtcaataa tccttttccc gtaccttttg agattactgt cagactggat caaataaaga
    54061 ttaacatgta agtgatcttg actatccgcc ttagataagc tgttaccaag gccaaggctt
    54121 cctaagagcg tagctagtaa cagcaggtgt tttactagac tacgctgaac aatattgtga
    54181 cgactaagca taagttattt tcccattcta ttgtaatata ccagaaaatg ttatcaaaat
    54241 aaagataaga tgtcaatgtc attaatggtg gttaatcttt aattaatggt cgttaatcta
    54301 gtatatcaga gagctagctt aggctggcag tggtcattct gtgcgtcttg gtacgaaatg
    54361 cccaagcaga tgcagctcac tagaatgatc aatagcctca acacaaagcc ccttacagct
    54421 tgacacaagc tgtaaggggc tttgttgtat taacagataa ctcaaatcct tgctttttat
    54481 aataaatcta aggtttttag cttgtcatca atcatgtgca gaacggttgc caaatcctct
    54541 gggttttgca cgaaatcaag cttgtttcca tcaatcttca tcttaggtga aacgtcatat
    54601 tgctcatacc agcttgggta ttcaccatgt acctgatggt aataggcttc taagtcagga
    54661 ttgtcgtcaa cctgctcaaa acgtctgccg cgcttttcaa tgcgctctag catcttctca
    54721 aaggagacat caatataaat cagcagatca ggccgttttt aaggcattcc ttcaagctcc
    54781 tctagcatat tggctaagag ctcttggtaa atttcaagct ctgtcttggt aacatttcca
    54841 tttttatagt taagtgtcaa gaagagctca tcttcaaaga ttgagcggtc aagaatatta
    54901 ttgtctgcct ggtaggcttc tttaatagat ttgaagcgct tgttcaaaaa gaaaatttgt
    54961 agtaaaaagg catatttttt agggtcttgg taatacagat caagaacagg attgttatca
    55021 acagcctcgt aaaatacctc tgttcctaaa tgctcaccca gtgcagcagc aagggaactc
    55081 ttgcctgcgc cgattgttcc agctaataca atcaacatgt ttctccttct atgtagtctt
    55141 agtgtatttg tgcaaaaatc gtttcaacct cagctaaggt tttagcgcgt gaaacggcac
    55201 tgcgaatttt ggcagcgcct gctgtccctc gcaggtaatg aggggctaac ccacgaaatt
    55261 cacgaacagc aatagcttct cccttgagcc tgatgaggcg cttgagatgg tctttagcaa
    55321 tatctagctt tttagcaaag ggcagctctg gcaaaacctc tcctgtctca aagaagtgat
    55381 taatttgggt gaagagataa gggttgttca tagctgcacg gccaatcatg accgcatcta
    55441 caccaatctc ctcaatcatg aacctagcgt cctgaacagt tctgacatct ccatttccaa
    55501 taaatggaat cctggtaata gctcttgaga cgcgtgcaag ggtttcatgg tcacaggtgc
    55561 cagtatacat ctgctcacga gtacggccat gcatggcaag agctgacaca ccagcagctt
    55621 cagcagccaa ggcattctca acagctagtg agctgtctgc ccagccggta cgcattttga
    55681 cagtcagtgg aatgtctaaa acagaggtta cctcctgaat gatatggtaa atcttatcag
    55741 gatcgcgaag ccacttggca cctgcttcat ttttaaccac cttgttaaca ggacagccca
    55801 tattgatgtc aacaatgtca gccttggtat ggctctggat aaaatcagcc gcacgcttta
    55861 gtccttcagc gtcaccgcca aatagttgga ttgacatggg gtgctcattg tcatcaatat
    55921 gaagcatatg cagggttttt tcgttattat agagaagtcc cttttcagaa atcatttcca
    55981 tgacaacaag gcctgcacca aattccttgg caatcgtgcg aaaggccgaa ttggtcacac
    56041 cagccatagg tgcaagcact gtacggtgag ggatttccac atgaccaatc ctaaagggtg
    56101 agttaagcct tgtcattgat cagcacctcc aaatcagttt ggtcaaattg gtacttggtg
    56161 ccacaaaatt ggcaaacaat ttcagccccc ttatcctcgt ttagcattgt caacaggtca
    56221 gctttaggga ggctcattag ggctgacgca aagcgctctc ttgagcagtc acactgaaag
    56281 ctcagctgct cttcagctaa tcgcttgtaa ggctcttcac cataaatagc tgctaacaga
    56341 gcgtctatat gattttccga cgctagaagg gttgaaatcg caggcatttc ctgaatgcgc
    56401 ttctcatagt ggctaatctc ttcgacagaa gctccaggca gcacctgcag cataaagccg
    56461 ccagcaacct tgaccttgtc ctcttgatct agaagcacat taaggccgac agcagatggt
    56521 gtctgctcag actctgtcaa gtagtaggcc agatcctcac caatctcacc ggtaatcaag
    56581 ggtgttgtag aggtgtaggg attgcctgtt ccatagtccg taattgtcac aaagtgtccc
    56641 tgtcccataa aaggaccaac cagtacttct ccagttgctg tttttttgat atcaacaccg
    56701 ggattttgaa tatagccctt gacatgccct tttgtgtcag caacagaaat aatatgccca
    56761 aaggaggaat cgccaataac cttgacagta accttactat ctcctttttg gttggcagct
    56821 agaatctgat tggcaatcaa ggtacgacca agtgcaaccg ttgaagatga taaggtatga
    56881 tgcctttcct gagcatatcg aacagtttcg gtgcaatcca aaacataggc cctgaaggca
    56941 ccggaggcag aaattgtttt aattagttta tccataattt ctattatagc ataatgaaca
    57001 aggcttgtgc tggttgcttt agaggaaagc tgcttgaaaa tagagaaaca ctatttggtt
    57061 aataatagca gctctataaa gccacttaaa aacagagcag tgctaacaaa tggtagtatt
    57121 cttgtcctta gcacgcagta agctaatcac ctaagtcagt acaatcaaac aagcatcaaa
    57181 aaacagctcc gataggttga ttaaaggaag aaatgataaa agagttattt cgtaatgctt
    57241 tgctgataat gagcaaggta atcatgtggt gtcgtatcag tgtacttttt gaaggttttc
    57301 aaaaaatggg tggtatcgta gaaataaagg agcttagcca cttctccagc tggtactcct
    57361 cttcgtaaaa gtagcttggc ttcttgtact ttttccttca aaatataggt ctgcaacgaa
    57421 atagaagaat acattttaaa aacagctcgt aaatgtgact ctgagatata aagatgctta
    57481 gcaatatctg atacctttaa ttttgaataa aggtgcttat cgacgtaata taaaatacta
    57541 ttataaattt gctgcttatc agaaacactt ttgttagtca atgattctga gaggctaata
    57601 atagcagctg ctcttatttg aagcacctta aggagatctg tagctttttc agttaggttc
    57661 ataaaatgct taatgcgctc gtagtttttg gcaacatcag tattttcagt aaagcttagt
    57721 tcaagcagct taataaaata aataatagaa agattttttt cagctcttaa tgcgggaata
    57781 gaagaggaga cgacatctga tgaagggata caattgattt cgtgctttaa tagctctgta
    57841 ttacccagct tgactaaatc aataatatga ttcaaataat ttaagacagc tggcacatga
    57901 aatgacgggg tattttccaa ttcgagatta gctataatat gaggatcctc ccagattagc
    57961 tgggcttcct ccagtaaatc attaatgctt tgctggcagc tcatttcaaa gttggtgtca
    58021 aaaaaggcat caacagctat caaaaggctt cgaatatgag aagcaggaaa atgaggaatg
    58081 gtagagatat agccaactag ctcttttttt gacttatcag gatagcgctt caagaagcta
    58141 tcggctaatt cctccttata gctatcctga aagaaagagg tgtaaaaagg cccaatgaaa
    58201 ataaacttgt caccaatagg aaacattaga gaggattcct caagcgttcc ctcataacaa
    58261 gtgagctcag tattactagg aatatctaat gttttaatta attcatagta ggggaatcga
    58321 cgctcctcgt catcataagc ctgaaggagc tcaagatttt gagaaagcac taaaacaggt
    58381 aattgtgata ggttatgcaa
//
LOCUS       DARYJX010000008        57161 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYJX010000008 DARYJX010000000
VERSION     DARYJX010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57161
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..336)
                     /gene="tnpA"
                     /locus_tag="TU257_000474"
     CDS             complement(<1..336)
                     /gene="tnpA"
                     /locus_tag="TU257_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL0833514.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYY"
     gene            complement(618..983)
                     /gene="rplL"
                     /locus_tag="TU257_000475"
     CDS             complement(618..983)
                     /gene="rplL"
                     /locus_tag="TU257_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL0833515.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(1048..1548)
                     /locus_tag="TU257_000476"
     CDS             complement(1048..1548)
                     /locus_tag="TU257_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL0833516.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(1577..1712)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1844..2485)
                     /locus_tag="TU257_000477"
     CDS             complement(1844..2485)
                     /locus_tag="TU257_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL0833517.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(2482..3249)
                     /locus_tag="TU257_000478"
     CDS             complement(2482..3249)
                     /locus_tag="TU257_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL0833518.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(3249..4001)
                     /locus_tag="TU257_000479"
     CDS             complement(3249..4001)
                     /locus_tag="TU257_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL0833519.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(4012..5142)
                     /locus_tag="TU257_000480"
     CDS             complement(4012..5142)
                     /locus_tag="TU257_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL0833520.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(5209..5895)
                     /locus_tag="TU257_000481"
     CDS             complement(5209..5895)
                     /locus_tag="TU257_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833521.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(5929..7281)
                     /locus_tag="TU257_000482"
     CDS             complement(5929..7281)
                     /locus_tag="TU257_000482"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL0833522.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(7334..8290)
                     /locus_tag="TU257_000483"
     CDS             complement(7334..8290)
                     /locus_tag="TU257_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL0833523.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(8287..9138)
                     /locus_tag="TU257_000484"
     CDS             complement(8287..9138)
                     /locus_tag="TU257_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL0833524.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            9240..10583
                     /locus_tag="TU257_000485"
     CDS             9240..10583
                     /locus_tag="TU257_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL0833525.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            10583..11371
                     /locus_tag="TU257_000486"
     CDS             10583..11371
                     /locus_tag="TU257_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL0833526.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(11995..12984)
                     /locus_tag="TU257_000487"
     CDS             complement(11995..12984)
                     /locus_tag="TU257_000487"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL0833527.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(13226..14995)
                     /gene="lpdA"
                     /locus_tag="TU257_000488"
     CDS             complement(13226..14995)
                     /gene="lpdA"
                     /locus_tag="TU257_000488"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL0833528.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(15204..16613)
                     /locus_tag="TU257_000489"
     CDS             complement(15204..16613)
                     /locus_tag="TU257_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL0833529.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(16737..17735)
                     /locus_tag="TU257_000490"
     CDS             complement(16737..17735)
                     /locus_tag="TU257_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL0833530.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(17815..18783)
                     /locus_tag="TU257_000491"
     CDS             complement(17815..18783)
                     /locus_tag="TU257_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL0833531.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(19289..21199)
                     /locus_tag="TU257_000492"
     CDS             complement(19289..21199)
                     /locus_tag="TU257_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0833532.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(21609..22394)
                     /locus_tag="TU257_000493"
     CDS             complement(21609..22394)
                     /locus_tag="TU257_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL0833533.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(22500..24161)
                     /locus_tag="TU257_000494"
     CDS             complement(22500..24161)
                     /locus_tag="TU257_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0833534.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(24371..25129)
                     /locus_tag="TU257_000495"
     CDS             complement(24371..25129)
                     /locus_tag="TU257_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833535.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(25126..25995)
                     /locus_tag="TU257_000496"
     CDS             complement(25126..25995)
                     /locus_tag="TU257_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833536.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(26009..27004)
                     /locus_tag="TU257_000497"
     CDS             complement(26009..27004)
                     /locus_tag="TU257_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0833537.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            27356..29026
                     /locus_tag="TU257_000498"
     CDS             27356..29026
                     /locus_tag="TU257_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL0833538.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(29115..30353)
                     /locus_tag="TU257_000499"
     CDS             complement(29115..30353)
                     /locus_tag="TU257_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL0833539.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(30343..31524)
                     /locus_tag="TU257_000500"
     CDS             complement(30343..31524)
                     /locus_tag="TU257_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0833540.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(31587..32063)
                     /locus_tag="TU257_000501"
     CDS             complement(31587..32063)
                     /locus_tag="TU257_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0833541.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(32241..33287)
                     /gene="rfbB"
                     /locus_tag="TU257_000502"
     CDS             complement(32241..33287)
                     /gene="rfbB"
                     /locus_tag="TU257_000502"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL0833542.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(33479..34075)
                     /locus_tag="TU257_000503"
     CDS             complement(33479..34075)
                     /locus_tag="TU257_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL0833543.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(34075..34944)
                     /gene="rfbA"
                     /locus_tag="TU257_000504"
     CDS             complement(34075..34944)
                     /gene="rfbA"
                     /locus_tag="TU257_000504"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL0833544.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(35001..36110)
                     /locus_tag="TU257_000505"
     CDS             complement(35001..36110)
                     /locus_tag="TU257_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL0833545.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(36165..36953)
                     /locus_tag="TU257_000506"
     CDS             complement(36165..36953)
                     /locus_tag="TU257_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL0833546.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(36943..37629)
                     /locus_tag="TU257_000507"
     CDS             complement(36943..37629)
                     /locus_tag="TU257_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL0833547.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(37703..38365)
                     /gene="nth"
                     /locus_tag="TU257_000508"
     CDS             complement(37703..38365)
                     /gene="nth"
                     /locus_tag="TU257_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL0833548.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(38365..39042)
                     /locus_tag="TU257_000509"
     CDS             complement(38365..39042)
                     /locus_tag="TU257_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL0833549.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(39109..39627)
                     /locus_tag="TU257_000510"
     CDS             complement(39109..39627)
                     /locus_tag="TU257_000510"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL0833550.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(39707..40075)
                     /locus_tag="TU257_000511"
     CDS             complement(39707..40075)
                     /locus_tag="TU257_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833551.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(40084..42294)
                     /gene="recJ"
                     /locus_tag="TU257_000512"
     CDS             complement(40084..42294)
                     /gene="recJ"
                     /locus_tag="TU257_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL0833552.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(42291..43055)
                     /locus_tag="TU257_000513"
     CDS             complement(42291..43055)
                     /locus_tag="TU257_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0833553.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(43055..43984)
                     /locus_tag="TU257_000514"
     CDS             complement(43055..43984)
                     /locus_tag="TU257_000514"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL0833554.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(43999..44637)
                     /locus_tag="TU257_000515"
     CDS             complement(43999..44637)
                     /locus_tag="TU257_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL0833555.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(44630..45868)
                     /gene="hflX"
                     /locus_tag="TU257_000516"
     CDS             complement(44630..45868)
                     /gene="hflX"
                     /locus_tag="TU257_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL0833556.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(45953..46843)
                     /gene="miaA"
                     /locus_tag="TU257_000517"
     CDS             complement(45953..46843)
                     /gene="miaA"
                     /locus_tag="TU257_000517"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL0833557.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            46976..47152
                     /locus_tag="TU257_000518"
     CDS             46976..47152
                     /locus_tag="TU257_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL0833558.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(47308..47945)
                     /locus_tag="TU257_000519"
                     /pseudo
     CDS             complement(47308..47945)
                     /locus_tag="TU257_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(48102..50366)
                     /gene="glgP"
                     /locus_tag="TU257_000520"
     CDS             complement(48102..50366)
                     /gene="glgP"
                     /locus_tag="TU257_000520"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL0833559.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(50392..51894)
                     /gene="malQ"
                     /locus_tag="TU257_000521"
     CDS             complement(50392..51894)
                     /gene="malQ"
                     /locus_tag="TU257_000521"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL0833560.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(52101..53123)
                     /locus_tag="TU257_000522"
     CDS             complement(52101..53123)
                     /locus_tag="TU257_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0833561.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            53370..54623
                     /locus_tag="TU257_000523"
     CDS             53370..54623
                     /locus_tag="TU257_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0833562.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            54923..56284
                     /locus_tag="TU257_000524"
     CDS             54923..56284
                     /locus_tag="TU257_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0833563.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            56284..57120
                     /locus_tag="TU257_000525"
     CDS             56284..57120
                     /locus_tag="TU257_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0833564.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        16602 a        13511 c        10760 g        16288 t
ORIGIN      
        1 atagtagcct ctagcccaaa actttcgatt tccatactta tattttaaat tagcgtgttt
       61 atcaaatatc atgagagcac ttttactttt caaatacccc atgaaatcgg aaatcgaaag
      121 ttttggaggt agcaagacga gcatatgaac atgatctggc atcatatgtc cctcaatgat
      181 ttccacgccc ttgtattgac ataggtgacg gaaaatatca attaagtcct gtctaatttt
      241 gtagtaaatg gattttctgc ggtactttgg tgtgaaaact atgtgatatt tgcacatcca
      301 tttggtatgt gataaactgt aactggtttt agccatctct ttttcctcct tgatctaacc
      361 tgaacaatta gattataaca ggaaaaagaa atggaagctc aaagccttgt cagccaccag
      421 catagctggt ggttttcttg tttttctcta cgagaaaaac tggctcgaag ccataataaa
      481 aataaaaacc ctgccaaaaa atctttggta gggtttttag caggaaacca aatcaattta
      541 tcagtttctc taaatcgctc taagcaatca ttaaaccttg atttactagg cttccgcaat
      601 caaattgcga tactctatta tttaagagtg atagttgctc cagcttcttc aagcttagct
      661 ttgatttctt ctgcttctgc tgctgcaaca ccttctttga tgttagcagg tgcgccgtca
      721 acaagacctt tagcttcttt aagtccaaga cctgtgattt cacgaactgc cttgataaca
      781 ccaacttttt tgtcaccagc agatgtcaac tcaacgtcaa atgaatcctt agtagcttct
      841 tcagcaccac cagcagcagc tacagctaca ggagcagctg cagtcacacc gaattcttct
      901 tcgatagctt ttacaagatc gttaagctca aggattgaag cttctttaat ttcagcaata
      961 atgttttcaa tgtttaatgc cattgtcatt tcctccaaat agttatatta aataatgatt
     1021 tgtagctcta ggctacctct aaaggcctta cgcagcgcct tctttgcttt ctgcaacagc
     1081 cttgacagcg tatgcaacgt tgcggactgg agcttgaagt acagaaagaa gcatagaaag
     1141 cattccttcg cggtttggca atgctgcaag tgcttgaatt tcctcttttg aagaaacaac
     1201 accttcgata gcaccacctt taatctcaag tgcttcagca gttttagcaa agtcgttgat
     1261 gactttagct ggtgcgataa catcttcatt tgaaaatgct actgcagatg gtcctacgaa
     1321 tatatctttt agctcgtcaa gacctgcttt ttcagctgca cgagtcaaga ttgagttttt
     1381 gataaccttg aactcaacgc cactttcacg aagtgaacga cgaagaacag tatcttgatc
     1441 aactgtaaga ccacgtgaat ctacaacaac gatacttaca gctgctttca ttttctcagc
     1501 gataagctca acttgttcag cttttttagc gataattgct tcactcatta gttttacctc
     1561 cgtttttatt tttgggctag gcacaaaaaa atcgcaccta aacctagaca cgaaagtaca
     1621 aatacgttat cttcaataat gacgttttgt gcctcggcag gaatattatg agcacgctcc
     1681 cctgctgtct taggtcagtt ttattcaaaa ccatagttag tatagccttt ttaaatgact
     1741 ttgtcaacct attttttaga aaatcttaaa taaaaaagga aagctcttgg ctttccgcta
     1801 aatagatctg attagtggct caaaagcgcc tcctaactta agcctaatga taagcaactt
     1861 gtgacgattg attgctataa cttagcccga tcaagctcca cagtatcatc tcataaataa
     1921 agaagaacaa ggcaaagcaa tgcccaaaaa aggcctctgg caaaatccaa atgacaggat
     1981 ctgtcagcgg atcaaacaac cagcttgaat ctcctacaaa gagaatttga tgaaaaaggg
     2041 taaagaactg atcaaagcca atcattaaag caaagcaagc aatcacaatt ggcaataagg
     2101 ctgctgctat tagccctctt cgaagcagca taacccttcc ttttttgatg ctctgataaa
     2161 aatagataat ggttggcaac ataagcaggc taaagatcag ctgtgttata tgaaacagca
     2221 ttttcacatc tgtaaaatgc tttagaccag ctcttgatgc tgaaaagctg gctagcttta
     2281 gctcacgaac aaaaggattg gttaagtaag tcagcaatat attatagttg tggagaatag
     2341 actttttgca catcaaaact gcctgctcta gttgcaaata atcaacctca atcggataaa
     2401 gcagccaaga taaatagata gttatcaaaa ctgccagtgc tagtagccaa agccaactgg
     2461 caatgaactt gcctttttca atcataatag ctcccactca tctaagctag ccaagacatg
     2521 atcaggctta attggaaggc ttggaacctc ttttgccttt gtaaagccgg ttgttactag
     2581 aatagttgcc atatcatttt gaattcctgc catgatatct gtcaggtaat tgtctccaac
     2641 catagccacc tcagaacgtg gtacctttaa gatctctagg gctttattca tgataatcgc
     2701 atttggcttt cctataaata ctggcttcac tctagttgct gcctcaagga gcgcatttaa
     2761 agcgccagca cctggcatta gcccacgctc tgttggaata tttaagtcag gattggtccc
     2821 aataaacaag gctccttttt gaatggcaag tgttgcaatt gataacattt cataggtaac
     2881 ctcagtatct aagccaacaa caacataggc tggattttct gtatcctcgg tatagcctgc
     2941 ctctgcaatg gcagacttta agccagtctc gccaatcaca taggctgttt tgcctcgatt
     3001 catatcattc atgtaatcaa cggttgccat tgtagcggtg taaatggttt caagacctgt
     3061 atgaacgtta aattgattgg ctagcatttc ctgaaccatt tcaggtgttc ttgtggtgtt
     3121 gttggtaact aagagataag ggataccttt ttcctgtaaa cgcttgataa agcgctcacc
     3181 agccgggata cgatttttcc cttgatagat ggttccatct aaatcaatta aataagcttt
     3241 atagggcact aatttgtctc actttcttta gtcgttatag gctgccattt gataatggcc
     3301 tgcgcattaa gctggcctga tgacctgatc tcatggtagg aggtcaaatg ctctagatga
     3361 tagcctgagg ttatttgagt gctgggcctc acctctttga tataggtcaa ggtaaggtgg
     3421 caaggtctgt ggtgtaataa aaattcatat cccaaaacgt catacatcca atccaaatac
     3481 ttactattat tggcatgacc attcatatca atgtcaaaat aacgaacctg ataagcttga
     3541 accataggat cctgaagctc atctattttg ataggacgct tgattttctt aacaaagtca
     3601 gcctgataag gcaccaccaa atcatctggt atcgcagctg ccttacgtgt ttgaggattt
     3661 agcagggcaa aatgagataa aatggtcatg atggcatgac ctgcctgatc ataaatgtga
     3721 aattgccggt aacaaaataa tttattgtaa gaaatagctt gcgtttcaat ggttactgtt
     3781 tccccaaacc ttggcatacg atcaatcgtt acatcataat ccgtaacaac ccaaatcaag
     3841 ccatattgct gaagtaacac ctcattgcct cgtccaattt cagctgattg tcttgctgat
     3901 accattaagc aatgtgctaa taaaaggggc agcttgacat cagccttaac atcacaaaaa
     3961 tcaaaagaca gcttaaggct ttcgctatac cttaatccca taacacacct cctaatctaa
     4021 gatgaatttt tcagcgacag aatcacctaa aaagaggcct tttttggtca ttctgataaa
     4081 gtccttgtcc tctaccaaaa gcccctgatt ctgaagctct ctcacaacag gaccatagcg
     4141 tgactcaaat gataggccaa atttttcttg aaaccgactg actgatactc ctgatttttt
     4201 tcgcagacca agaaaaagct cctcctccat catctcctcc ttggtgagca cttcctcact
     4261 taacctagca tttccatctg ctactgcctt taggtaatgc tgaataggaa cccggttgcg
     4321 gtaacgaatc ccatcaagat agccagaagc ccctgcgcca cagccaaaat actcatcatt
     4381 attccaatac atcagattgt gcctgctttc aaagccaggc ttagtaaaat tagaaatttc
     4441 gtaatgctca aagccactgg cttccatttc agaaataata tactcaaaca tctcagcttc
     4501 caaatcctca gtgggcaaat ggagcttgcc acgacgcatt ttgttcataa aaacagtgtg
     4561 atgctctagg ataaggctat acaggctaag gtgaggaata tctaaagcaa gtgccttagc
     4621 cacattttcc ttgacctgct gcatggtctg tccaggcaaa gcataaatga gatcgataga
     4681 catattttga aagcctgcct ccttaagact agcaatggtc gtataaatct gagcctcagt
     4741 atgactgcgt ccaatctgct ttaattgctt gtcattaaaa gtttgaacgc ctagggaaat
     4801 ccgattgaca gccgattgcc ttaatactgc aatcttatcc tcagtcaaat cacctggatt
     4861 ggcctcgatg gtaaattctt caagctggtc tagctgtagg tgctgctgca aatggctcag
     4921 caaataatca agctgattgg ctgttatggc tgttggtgtt ccaccgccaa tataaagtgt
     4981 cttcaaggag ctgatctgat aggattcaaa ttccttaatc agtgcctcta ggtaggcatc
     5041 gacaggctga tttttgataa ataccttaga aaaatcacaa tagtagcaaa tttgtgtgca
     5101 aaaaggaata tgcacatagg ctgaggttgg tttttttgac atggtaatat tatatcattt
     5161 tagctcagaa attcatgcca agtgattagc tttttgacat gtactaacct aaggctgctt
     5221 ctttttctcc attctcacaa aggaatgact actcccatta gcatactgct caaagcttga
     5281 ggttggctga tagcccattt tttggtagag gctttgtgcg cctttattaa agctagcgac
     5341 atttaaaaca taggtttctt gcggataagt agtgctagca aaggcttcaa tgctgcccaa
     5401 aaaagaaaca ccatcttcct gaccagtagt atcaggggcc ataccaagac caatctcaag
     5461 ctctgattcc tgttcaaaaa agctggcaaa gccaaaaaga acaccattgc gaagcacttg
     5521 aaagtaatgc tctccacgcg ccttgggtga caatattgac tgatagtcct caggatcagc
     5581 agtcatgcta tagcactcat aagctgggct atagatccag tcatgcgcaa tgatttcagc
     5641 actatgctgt gtcatcggca tcaggtaaaa agaagactca gacaataagc gatgaaaggt
     5701 cttgttgata tgctttatgc gacgccgctg cacatcaggc tgatctgttt gataaatgta
     5761 attagcatag ccctcctgat attctggaat cattgtcaaa tacagctttt gggtcaactc
     5821 atcaagctga ctagcaatcc tatccactct atgctttatc atattacctc caattctaat
     5881 gctgcttgat agcataaaaa gtgccgaagc aacgacactt tttctagatt aatcaaggcc
     5941 aatttccgca cgaacaaccg ctgcaatggt atcaacataa tagtcaactt cttcattgct
     6001 tggtgcctct gccatcacac gcaacaatgg ctctgtgccg ctaggcctta ccaaaatgcg
     6061 accattacca gccatttctc cttccatctg agcaataacc tcagcaatag caggcacttc
     6121 catagcacgc tccttcatgc tgttgtcaac acgaatatta acaagctttt gtgggtaaat
     6181 agtgacctca ctggccaatt cggagagagt tttacctgtc tccttcatga ttttggtgag
     6241 ctgaacagct gtcagttgac catcaccagt tgtattgtaa tccatgataa tgacatgccc
     6301 tgattgctca ccaccaagat tgtagccgaa ctgacgcatc tcctcaacaa cgtaacgatc
     6361 accaacagct gttaccttct tatgaatgcc acagctatct aatgccttgt gaaaaccaag
     6421 gttagacatc actgttgtca caatcgtatt tttagctagc aagcccttct cagaaagata
     6481 cttgcctatg ataaacatga tcttgtcgcc atcaacaata gcaccatttt catcaacagc
     6541 aattaaacga tcactatcgc catcaaaagc caatccaata tcagaggctg tttctgtcac
     6601 caagtcctga agcttttcag ggtgtgtaga gccgatacca tcattaatgt ttaatccatt
     6661 tggattctca ccaataactg taatgtctgc atttaaatct aaaaagacat tacgagctga
     6721 aacagaagct gcaccgttag cagtatcaag agctatcttt aaaccgtcta aatctgctcc
     6781 agtagtaacc aagaatctct cgtacttgcg caagccttct ggataatcaa ccaaggctcc
     6841 taagccctcc gcacttggac gtggtaggag gtcctctttg gcatctaaga gcgcttcgat
     6901 ttctagctct tgctcatcag ccaatttaaa gccatcactc ccaaaaaact taatgccatt
     6961 gtcaagagca ggattgtgac tagctgaaat catgacacca gcactagcct tttctgtacg
     7021 gaccaaatag gacacaccag gagttgcaag aacaccaagc ttatagacct ctatcccaac
     7081 agaaagcaag ccagcaatca gggctgcctc tagcatttca ccagagatac gggtgtcacg
     7141 agcgacaaaa actctaggcc tttcagtctc atgctgactt agcacataac caccgaaccg
     7201 accaagctta aaagcaagct ctggggtcaa ctctacatta gcctcgcctc gaacaccatc
     7261 cgttccaaaa tattttccca taatttatat cagctaaacg cttcctccat tccattttcc
     7321 tagctattat gctttatttt ttaattgttg tcaactgaac ggttactacc gaaggctcta
     7381 tagaaacctg atttgaaacc aagctgaccg ttttgctcgt gtttttggtg acgtcagaaa
     7441 tattgacctc tgccaccacc tcatcaatag tttcaaggac ctcccgacta ccagaaataa
     7501 cagcggtctg cttggagagc ttatactgga tatctgacag actgtcatcc attagtccaa
     7561 ctgcctcgac tcgaatagga actgatttgg tgattttttt gacagaaact gacaaattag
     7621 ccttggctgg atcgatcgca ctagctaaaa tggtaccatc ggcagctact gcctgcaggg
     7681 ttactcggct gctataatta gcatctagca cctgatcatc aggtaattta gcgacaacat
     7741 gatctatcaa ggcaatagta gactcatcac ttgtgacctc aaccttgtca atacctgttt
     7801 caattttgct aatctcatag cccttagcca gctgcttact atcgacgctg ccacgcaccg
     7861 gaaaggtctt tgttttctta tttccaatcg ttaccgaaat cttatcagga gaaacagttg
     7921 ctgtcacacc agtaggtaga ttgataacct ttagggtcac cgttgcagta cctggcttac
     7981 tctttgttag atcagctacg atcttaaagc ttctagtgtc actgtttacc tctgaatcca
     8041 gctttatgcg gttggtagag gtcagataaa cctctgcacc gtaagaatag ccgctgatga
     8101 agtactgatc actatcatac ttgatatcaa taggaacgtc ctttaagcta tgggtgtagg
     8161 tttcaatagg gctataaatt tgagaattag aatgattatg actgctagaa gcagcggtca
     8221 aaaaaagaat aatcgcaaaa aagattgaca ctaagcccag cccaagacga ctatttaaaa
     8281 acctcttcat ttagctttgc ctcctaagat ttttttatac caaggtaatg tcgcaccggg
     8341 ctcattcatc aaatgagtct tgagaaccgc ctcaagctct tctgttgaaa ggtcgtgtaa
     8401 aaattgaccc ttacgagcga tagagacagc tcctgtctcc tcagaaacaa ttatcgttac
     8461 agcatcagaa ttttctgaaa gtccaattgc tgctctgtga cgtgttccaa attctttgga
     8521 aatcgacatt gattcagaca aggggagata agcacaggct gcagcaattt tattgttagc
     8581 cacaatgacc gcaccatcat gcagcggtgt gtttgggata aagatattga tcaatagctg
     8641 actagaaata tcagcattta ggggaattcc tgttgcgata tattcctgca aggtctgcgt
     8701 ttgctcaata gcaatcagag caccaatctt ccgcggtccc atataagcaa ctgattttaa
     8761 gagcgcatca accagcatct cctcatcact caagctttgc ttttgcaaaa atacctgtgt
     8821 tgatcggcca aatttttcaa gccccgctcg aatttccgga gcaaaaatca ccacacctgc
     8881 aatcactcca taggtgatga cctgattcat cagataggtt atagtcgtaa accctatcca
     8941 ctcggcaatc acacgaatga tgataaagaa tataacccct tgtaccaagg acatgatctt
     9001 agttcctgcc aaggatttaa taaaacggta aatcaaatag gctactatta aaatatccag
     9061 caaatgaacc accaacatca aggggtcatc aatcaggctt agtaaaaatt ttgtgtcaat
     9121 acttgataaa ttactcatac aattctcatt tctatgtcag atagatacct ctaacattat
     9181 atcacgtttc aagatgtttt ccctatctaa aatttaagaa cttatgttaa aatattaaca
     9241 tgaaactaaa gacactactc gctatagcag ccggaaggac tgcgcagctc attttaaata
     9301 aaatcggaag aggctcaacc taccccggac gattggcctt gatgtgggat aaggatattt
     9361 tagacacact tgccaaggac tatgagattg ttgttgtgac agggacaaat gggaaaacct
     9421 taaccacagc tctaactgtt ggtatcctaa aagaagcctt tggtgaggtt ttgactaatc
     9481 caagtggcgc caacatgatg acagggatta cctctgcctt tttatctgct aaaagaaaaa
     9541 aaacaggcaa gcctattgcc gtcttagaga ttgatgaggc aagccttgca agggtaacaa
     9601 catacattaa gccaagtctt tttgtttaca ctaatatctt tcgagaccag atggatcgct
     9661 acggtgagat ttacaccacc tatcagatga ttgttgatgg tgctagtcaa gcgccgaagg
     9721 caaccattct agctaacggt gatagcccta tctttgcctc aaaggacctg gttaatcctg
     9781 ttaaatatta tggctttgac acacctaagc atgagccacg cctagctcac tacaacactg
     9841 aaggcatttt gtgcccaaaa tgtgaacaga ttctccgtta tcgtctcaac acctatgcta
     9901 atctaggaga ctatacctgc ttaaattgtg atttccaaag gcctaagttg gattacaagc
     9961 taacgcaatt aaccagcatt acccatcata gctcagcctt tgtgattgac gatcagactt
    10021 atcgcataaa tgttggagga ctctataaca tctataatgc cctcgcagct gttgctgttg
    10081 ctgagttttt tggcatttct gctgatcaga ttaaggctgg cttcaataaa agcaaggctg
    10141 tttttggtcg tcaggaaacc ttctccatca acggtaaagc ctgtacgctg gttctcatta
    10201 aaaaccctgt gggtgctagt caggcactag aaatgctgcg cctagccgat tatcccttta
    10261 gcctatctgt gcttttaaat gctgattatg ctgacggtat tgacacaagc tggatttggg
    10321 atgctgattt tgaattgatt aatcaaatgg acattactga gatcaacgcc ggtggggttc
    10381 ggcattctga aattgcaaga cgcttacgag tgacaggctt tgatgaggct aaaatcacat
    10441 cattcgataa gcttgaaggt atcatgcaag ccattgaaaa ccaagaggct gagcatgcct
    10501 atatcctagc gacctatact gctatgctag catttcgtga gctgcttgcc agccgccaca
    10561 ttgtcgaaaa ggagatgatc taatgaccta tacctcgcta caatctccgg aaaatcgcga
    10621 ttatcaatac gaccttcata ttgctcacct ttatggtaat ttgatgaata cctatggcga
    10681 taacggcaat gtcttgatgt tgaagtatgt cgctgaaaag ctaggcgcta aggttagagt
    10741 tgatattgta tccattgggg atacctttga ccaagatgat tatgacattg ttttctttgg
    10801 tggtggtcaa gattatgagc aagccattgt tgctagagat ttgccatcaa aaaaagaggc
    10861 cttagcagcc tatattcacc aaaataaggt actccttgcc atttgtggtg gctttcagct
    10921 gctgggacag tactatattc aagccaatgg ccttaaaatc aatggcattg gggttatggg
    10981 acattatacc ttaaaccaag ataataaccg ctttatcgga ggcattaaaa ttcacaatga
    11041 tgactttgac gaaacctact atggctttga aaatcatcaa ggacggacct ttttatctga
    11101 cgatgaaaag cctcttggac gtgtcattta tggaaatggt aataataaag aggaccaaac
    11161 tgagggcgtc cactataaaa acgtttacgg cagctacttt catggaccaa tcctttcgcg
    11221 taatgtcagc ctggcctatc gcctagtcac aactgctctc aaagaaaaat atggctcgac
    11281 tgtttcctta gcggcctatg ataagatctt acagcatgag acctcagagg aatacgctga
    11341 tgttaaaagc aaggctagct ttgacagtta agtccttctc atagcctgat taaaccacaa
    11401 cagacatgca aaacagttat tcccgaatga aaatatagat ttaaatagac accctcaatg
    11461 tttttcctat cataaaatcc ataaaagata agacatattc ttgcaataac tgaacattga
    11521 aagacagaaa gctttctgtc cttactaaac atctttcatg cgtctgtcgt gctgatcaag
    11581 cgagataacc ccaaaaaagt gctagcacag taacaaaatg gctatgacca tatgtctgtg
    11641 cagctctact gtcactgcat agacaggcta gaggggacgc cctacttggt tcagcgatct
    11701 aggggtaggt ctagcttgtt tgtgctgagt ctgtttcggt agcaaagatt gaatcctgct
    11761 ataagatact ctcaaaaaga ttaacccaaa agccttgcaa cacatttaac gtttttaggg
    11821 ataagtaccg atatgcagac acatagcagg agatctatgt gtctggtacc aaaggacaca
    11881 aaaaactaaa gtaacacact aaaagccaca tgatacccat ttgatagggg gcgtcatgtg
    11941 gcttttttct atctcactgt tcattacaaa aagccaaacc agcttctttt tgcattaggc
    12001 aacaatggcc tttgccacct cttctactgt catacgtgag aaatattgtg ttgtatcaat
    12061 ggtttgaaga cgctcaagca catcagcata ctcgtatttg caaccaatga gtaggctttc
    12121 aatatcctgc acgtccttaa taccaaagaa atcaccgtag atcttaagat tcttaataac
    12181 agaattttca acattagcaa aggttgagat tttaccggca gggtagcgaa cattacgttc
    12241 aatcgtgtat tcaggtgcct ttccataggt ccaatcccag ctcccaaatt gctcctcagc
    12301 cgattgttga atcttagcca gctcgtcctc tgacaagacg tattctgtca tgtctggata
    12361 ggtctccttc attttaacca aaatcttgtc tgaaaatgct tctacgctga ttttttctgg
    12421 cagctcattt aaaatattgg tcacgcgggc tcgtacagat ttgactcctt tggactcaat
    12481 cttatcctta ctgaccttga gcgcatcacc aagaacagtc atatccacat caaacaagag
    12541 acagccatga tgcatcatac gtcccttata ataggcttga gcattgccac agattttctt
    12601 gccatcaatt tcaatgtcat tgcgacctgt aaaattagcc ttaactccta aatcagccaa
    12661 ggtctcaata actggctgtg agaaggtttt aaaatcaaag gctccttctg ttgttttatt
    12721 ggaaataatc gtgtagttaa ggttattgag atcatggtaa actgcaccac cgccagacaa
    12781 gcgacgaacc acatgaatac catgctgttc gatgtactcc ttgttgattt cctgaatggt
    12841 attttgatgc ttaccaataa taatagccgg ctcattgatc cagaggataa acaattcatc
    12901 ctcatcaacc aattctctaa aggcataagc ctctagagca atgttaaagg cagggttgtg
    12961 gctcttatta acaatgtatt tcatttctat ctcctatagc gataatcgtt atcatattct
    13021 attctttatt ctaatggaaa ctcttacaaa agacaagcta aaagaggcta gcaaaagcaa
    13081 gggaactagt aaatgcttcc tcaatcaaga accatctgca agctagcagt aaagcttgat
    13141 ctaacttaaa gagccttcct tgtatcaacg aaagagctga gaaatctttt tcccagccct
    13201 tttttatcgc agctatatag ctagcttatt ttttacgttt tggtgggtta tgaatggctt
    13261 cgccaagcac atctgcaaag gcttcgtaca tcacctctga gaaggttggg tgtccatgaa
    13321 ttgacaatag caattcatca actgttagct cagcctccat gattgtggct gcttcattga
    13381 tcatttcagc ggctgctgga ccaatgatgt gaacaccaag tatttcatgg tatttagcat
    13441 ctgcaataac ctttacaaag ccatgagcct cgtttgacgc aatagcacga ccatttcctg
    13501 taaagctatt tttaccaata agaacatcgc catattgctc acgagcctgc tcttcagtta
    13561 aaccaaccat agcgacctca gggtgagtat agaccgccgc tggagtgtat tttaggttag
    13621 ccttacgtgt tgtgctgcca tgcatggcat tctcagcagc cacctcaccc atacggtaag
    13681 cagcgtgggc aagcatttta gtgccgttaa catcacccgg tgcataaatg cctgggattg
    13741 acgtttcttg gtagtcatta accttaatgc ggttacggtc catttcaagg ttgaggtttt
    13801 caagaccatt catctgtggc acacgtccaa tagatagcaa ggccttttca gcaacaacct
    13861 cttcgccatt attaagcttc aaggtcaact ggttgttggc ttcaacaatc tcagagacac
    13921 caactgaggt ctttattgtc atgcctttct tagaaaggat tttttgaagc tccagtgaaa
    13981 cctccttgtc catggcagga ataatgcggt cagccatttc aataactgta acctctacac
    14041 cgtaagaggc ccaaacaaga ccaagctcaa taccaacaac accaccgccc ataacagcaa
    14101 gtgatttcgg catttcacgc aaatcaagaa tatcatcaga tgtcaagaca agcttagaat
    14161 caatccctgg aatattgatg cgtgagacct tagagcctgt cgcaagaata atattgcgcc
    14221 ctttaatggt ttgcacacca atggtaaccg ttttatcagg atttacctga ccaaggccat
    14281 taaagatggt taccttgttg gctttaagaa gcccttgaac cccacctgtt agcgtcttaa
    14341 caaccgtatt tttaaagtca actgtcttat ccatgtcaat agtatagttg gttgaagcaa
    14401 ggttaatccc gcgtcctgct gcaatcttga tgccatcaag gatttcagca tttttgaggt
    14461 aggtttttgt tgggatacag ccaacgttta agcaggtacc gccaaattca gatttttcaa
    14521 cgatagcaat cttgccgccc agctgagcac cacgaatagc agcgtagtaa cccgcaggac
    14581 cgccaccgac aacaatgatg tcatattcat cagcagcaag ctctgccttt ggtgctgatg
    14641 gcgctgatcc ttgatccggt gcctttggca cctcaagacc agccgcctgt aaatcctcgg
    14701 ttgtacgcgc aacattgaca tcagccgctg ctgggcttga tacatcgata gcttcacccg
    14761 cagctccaat gtagccgata acttcggtta cagggactgt ctcacctgcc tggcgaatga
    14821 tttttaaaag cacacctgag tcttctgctt ctaattccat attggtcttg tctgacatga
    14881 tttccagaag aatgtcaccc tcgctgacag tgtcaccctc ctgctttttc cactcgatga
    14941 tctcgccttc ttgcatgtca acaccgagct ttggcataat aatttcaaca gccataatga
    15001 tattgtaagg aacgttcaaa tgcaatcaga tgccttaaca atcagcactg gctaacataa
    15061 gcctgctaaa agccctgcat ttagctcata gctagtgact acgagctcgt tccagatcct
    15121 ttctatagtt ttaaagaatt atcttttcgt tactttgttt ctgaaatatg ctctctttgc
    15181 atcgcaggcc ataaggcctg tcatcagatt agcagttcaa atggattttc catcaatttt
    15241 ttgagatcaa ccatgaattt agcaccattc atgccgtcca ccagacggtg gtcaattgtc
    15301 agacacattg ccatgattgg acgtgcaaca atctcaccat cgaccactgt tggggttgga
    15361 atggttgccc caatacctag aatagctgaa ttaggctgat tgataattgg attgaaggtt
    15421 ttggtgccaa acatacccag atttgtgatg gagaaggttg agcctgacat ttcggtagcc
    15481 tttagcttgc ctccttgagc ctttttgata acgtccttag aagcaaggac aaactctgag
    15541 agactcatct tatctgcacc atgaacaact ggcacaacta gcccatcatc aagtcctaca
    15601 gcaataccaa ggttgacaaa gcgatgaagc tcaatatcat tagcatcatt aatcaatgac
    15661 gcattcatgt attcgtgctc tggcttcatc aaggtcttaa caacggctaa accaatcaag
    15721 tcagtaaagc taacctttag ccctgtttta gccatgattg ggtcaatcag cttcttgcgc
    15781 aaggcaatca tttcggtcat gtcaatgtca taattaagcg taaaggttgg tgctgtaagg
    15841 taggaatgtg tcataccctt tgaaatagcc ttacgcatag cagacatctt cttaatttca
    15901 acaccctctg gaagctcctt agcaggcttt tcttcagcaa tagatgcttt ttccacagca
    15961 ggtgctgctg cgccaagcac agccaaaatg tcctccttgg taatcttgcc accaatacct
    16021 gttccgacca ccgctgcaag gtcaactccc ttgtcggcag ctatcttacg agcaagtggc
    16081 gttgccttag gctgagctcc tttgaagcct tcaacgtctt ctttgtggat acggcccttt
    16141 ggtcctgttc ctggcacttg gttaagctca attcccattt ctgaagctgc tttacgagct
    16201 gctggcgttg cgcgtacctt ttctccgaag gctggagcat tggcaactga tgctacctga
    16261 ggcgctgttg aggctgcttc tttcggtaca gttgttgtat tagcttctgc tgatgttggt
    16321 actggaattt cagttgtttt ctcacttgaa gcagtactat tatcaacaga ttcacctgca
    16381 gcaccaatat agccgataac ctcagtgaca gggactgttt cacctgcctg gcgagtgatt
    16441 tttagaagca cacctgaatc ctctgcttca agctccatat ttgtcttgtc tgacatgatt
    16501 tcaagaagaa tgtcaccctc gctaacagtg tcaccctcct gctttttcca ctcgatgatc
    16561 tcgccttctt gcatgtcaac accgagcttt ggcataataa tttcgacagc catatatttc
    16621 ctttcattta atcccgcagc ccatgatctt aagaccagat acagctgctg aaaaaaggga
    16681 tactgtttta tcagcctgat gaagaaagcc tctaagctaa gacttccttt gccatgctaa
    16741 tttcccttgt tgaccatttt tacaatagca gccttgattt tagcaacatc tggtaagata
    16801 gcttgctcaa gaacacgtgc ataaggtact ggtacgtcct cactagcaag acgcacaatt
    16861 gggtgatcaa ggtaatcaaa ggcttcactt tcagtgacca ttgctgcaat ctcaccgata
    16921 aagccaccag tcttataggc atcattaaca agcataagct tccctgtctt cttaacagaa
    16981 ttaataatta attccttatc tagtgggata agggtacgtg gatcaacaac ctccacatta
    17041 ataccatcag ctgcaagctc ttcggctgcc tgaaggacac gctctagcat acgcccatag
    17101 gaaacaatgg ttacatcagt cccttcacgc ttgatatccc ccttgccaag tgggatataa
    17161 aaatctggat cctgattgac ctcttctttt ttaccgtaca aggccttagg ctccatgaaa
    17221 ataacaatat tgttatcacg aatagctgac tttaaaagtc cctttgcttc gttagcagtt
    17281 ccaggtgcaa ccaccttgat cccaggaata tgcgtcaacc aagcctcaag agattgcgaa
    17341 tgctgagctg cagatccaat tcctgagcca gaagcaacac gaaaagttgc tggcgtgatc
    17401 aagccaccac caaacatgta gttgtttttt gccccattat taacaattgc atcaagtgca
    17461 atggtaataa agtccataaa agtaaggtca acaatcggac gaagccctgt aattgctgaa
    17521 ccaatcgctg cacctgcaat agcagcctct gaaatcggcg tatccttgac acgtttggca
    17581 ccaaattcct caatcatgcc aacagaagta ccaaagtctc ctccgtaaac acctacgtcc
    17641 tcacccataa ggtaaatcgt gtcatctttg cgcatctcct ctgtcatggc aagattgata
    17701 gcctcacgca aagccattaa ttttgtttct gtcattatta tctcctaatg tttacaaaat
    17761 agaattgtca atgttactgt gaatagattt ttgctcgatg tgctagcaga tcagctagtc
    17821 tacccaaacg tcctcaaagg ctacagaaat gtctggatct ggactatttt gtgcaaactc
    17881 ataagcgtca tcaatttctt gcttgacctg tgcttgaagc gcatctaatt cttcatctgt
    17941 agcaatgcct tcacctgtta ggtaagcgcg atacttaagc attgggtcct tttccttcca
    18001 ctcatcaacc tcttctttgg tgcggtattt gccggcatca gcagttgaat gaccaaacca
    18061 acggtaagac tcaacctcaa caacagcagg accattgcca ccgcgaacat gctcaacagc
    18121 cttactcatg gtttcataaa ctgccatcac atcgttgccg tcctcacaat aaaagcctgg
    18181 aataccataa gcctcagcac gcgtgtagag gtgaggtgta tttgtggcat tgttaatgct
    18241 catggaaatc ccatagcggt tgttaatgat aaagaaaatc acaggaagct tccaagttgc
    18301 tgccatattg acagactcat ggaaggagcc ctcatttgtt gcgccatctc cagaaaaggc
    18361 cacaacgata ttgttggtcc ccttgtattg ctgtgtcaag gcagcaccta ccgcaagggc
    18421 atagccacct ccaacgatac catttgttcc atagtttcct ttttcaaaat cagccaagtg
    18481 cattgagccg ccgcgtccct ttgacacacc tgttacctta ccggctagct cagccatcat
    18541 tttattgagg tccatatctt tagcaataga ttgcccatgc ccgcggtggt ttgaaaaaat
    18601 aatatcatca taggtcaaat gtgccacagc gccaacgttt gctgcctcct caccaactga
    18661 gaagtgtgtc atgccctgca caaatccacg acggacaagc ttattaatac gtgaatcaaa
    18721 ttcacgaata cgctccattt taaggaacat atctaaatgt tgttctttag aaactgttac
    18781 catttcggcc tccatattat catattactt cctaatcata aaacttttct tcacaatttg
    18841 caaggatttt aatcgctttc tttgtgacta taaaagcttt tttaagacgt tttagtttgt
    18901 ggtttcacaa gctagattgt tatagcatct gttacattta tatataacag attgaaaaat
    18961 gagtcagtgt ttattcaggg aggtcaagca cctattgact ttgatagtca gaaatatcat
    19021 cactctttaa gaggaaaata ggctctaaat gacctgtttc ttctagcaca atcatgatca
    19081 cctaccaaac gaacgctttg cttgcctcgc tccgatagag gcgaaatgaa ctaaaaatcg
    19141 cataactaaa aatgcctgat tttacctgaa aatcagacat ttaaaagctt taagacatta
    19201 gactcaggct ctaattataa tcctctaaga aaagcctgct accttgcact acccaagaat
    19261 agcaaggcaa tttcattatc tcaccaggct actccagctg tcctgcaatg tcctcccact
    19321 ccagcagcaa ggtctcctgt ttctgattaa gctgatccaa ctctttttgc cagtctatca
    19381 gttgagtcgt atcatttgat actagcattt gagcttctat agccttagcc tgtgcttcta
    19441 gcccttctaa ggtctgctca atctcctcaa agcgccttgt taagcgacgg tattcctttt
    19501 ggctggcctt ttgaagctga taatcagtta cagcagcttc tgctacatca gtctctacta
    19561 cgtgatctgc agcagctaga cgggctaatt cctcccgctc tgcctttttt tctacataat
    19621 agtcgtagtc ccccagatag agtgttgagc ctgcttcagt tatttctaaa accttagtgg
    19681 ccactcggtt gataaaatac ctgtcatgac taacaaacaa caaggtccca tcaaagtcaa
    19741 tcaaggcatt ttctagaacc tctttgctat caatatccag gtggttggtt ggctcatcta
    19801 gaatcagaaa attgtccttt ttcatagata attttgttaa gagcagccga gccttttcgc
    19861 ccccagatag catggccaca gactttttga cgtcctcacc agaaaagaga aaggcaccta
    19921 agcggctgcg gatctcaagc tcagctgtcg ttgggaaatc acgccaaagc tcctccaata
    19981 cagaattact accagtcaga tgagattgcg tttggtcata atagcctgtt tcaacattag
    20041 tcccataatg gcatgtccct ttaatcaaag gaatctctcc aataatggat ttgagtaggg
    20101 ttgacttgcc aataccattt ggcccaacaa tagcgattgc atctaaccta cggacatcta
    20161 gatgaattgg ctcagctaaa atatggtcat tgtagccaat agcggcgtct gtcacctgca
    20221 aaacaacatt tcctgagggc ttatcaatct gaaaagtcat actagctgat ttgcgagagc
    20281 tacttggctt gtctaagcgt tctagctttt ctagctgctt gcgtcttgcc tgagcacgct
    20341 tggtcgttga cgctcgaaca atgttttttt ggacaaaatc ctctagctta gcaatctctt
    20401 tttgctgctt gtcataatgc ttctcttctg ctgcaagctt ttcagccttt aaatcaataa
    20461 agcgtgagta attaccaaca tagcggtcta agctattttt agtcagatca agtgtgatgg
    20521 ttgcgacctt atccaagaaa tagcggtcat gactgacaat gatcaaggct ccctgataat
    20581 ttaccagata atgctccagc caggcaatgg tttcaatatc taaatggttg gtcggctcat
    20641 caagcaccaa tagctctggc ttttctagta gcatttttgc cagggccaaa cgggtatttt
    20701 gcccaccaga aagctctgag attttcattt cccacatgct ttcgtcaaac ttaaagccat
    20761 ttaaaatagc tcgaatatct gactcatagg tgaagccatt tcgcaagcga aagctttctg
    20821 acagccggtc atagtctgac atgagctggt ccagagcttg ccctgatcga ctggccatat
    20881 cagcctccat ttgccttagt cgctgctcat caaccctcaa ttcagcaaat acctttagca
    20941 tttcctgata aatggtcttg tcagactcaa atcggctatt ttgtgccaaa taagataggg
    21001 ttaagtccct ttttcgacta acctcaccgc tagttggctc ttcttctcca actaaaatct
    21061 taagaagggt tgatttgcca gcaccatttg gcccaaccaa ggcaatgcga tcacgttcac
    21121 caacctgcag cgataggttt tgaaaaagca cctctcctga aaaagagcgc tcaatgttat
    21181 ttccttgtaa tataatcata cccttattgt agcaaaaaaa tgcccttttg gggggcactt
    21241 ttagttattt ttacaggtaa gataagactc atcaacaagc taaagacata agccttaggc
    21301 taacatcgct tatcaccctt agtggtattt atctgatgag acaaactgct gcttgaaaaa
    21361 ccagtgggtt gacctgttag cgtatccaac aatcgcacca cctgctcagt tatgcttgaa
    21421 atgctattag ccagtgagga atcactatgg ttcgaataat aaatcaaacc aaaaataagc
    21481 aataccaata ctattagggt ctgcaaacag cctctgacaa gctgccagac aagcttcagc
    21541 agaagctttg ggaggcataa gaggatagtc agtagttttt tcatcgtaat aagcctaaat
    21601 tctttcgttt aggatagcct ttcttccttg tggtaagcaa tcggcagcca atctaatagg
    21661 gcctctagct gctgattcca ataataccat tcgtgcctgc catgatcctt acgataatca
    21721 atagtcaagc caagccttct caactcagca actgcctttt cattggcttc aaacaaaaag
    21781 tcctcatagc cacaccaagc gtatagctgg gtttgaccat cactttctgc tgctatactt
    21841 gtcaaataat gctttttgat atcaggagca ttcaaatctc caaaaacacc ctgccaataa
    21901 ggcagctcac ctataccttg ctgtaatagc atttccggcg aaaaatgcaa ggccccagaa
    21961 aaggaagcag cataggaaaa gcgattgctt tttaaggccc atttaaaggc accatagcct
    22021 cccattgaca gcccagcaac aaaggttttt tcacgcttag tggtcatatt aggaaagaaa
    22081 gaagctaata gccgaggaag ttcctctgca atagcttggt aataattcat accgtaggtg
    22141 gtatcggtat accagcctaa atcagtcgat ggcatcacca cgattaaatt ggtatggcga
    22201 agcagccttt caatattagt ccgcttttgc caggaatttt catttcctcc cataccatgt
    22261 aacagataaa gaactggaat atcttggtag ccttgctctt ctgggctaag ctcagactga
    22321 tcagggtaga tcaccttgac atgtctttcc atagccaaga tctctgaatg atactcaatg
    22381 ctaatgcttg ccatcagctc acctcctttt taatatcacc aaagcataag gaaagcccac
    22441 tcttaagacc taaaagccag atcctatttg accagctttt aggcagggct gtatctgtat
    22501 taacggacct ccataacaac cggaagaata gctggccgac gcttggtctg ctcaaataaa
    22561 aaccttgaga gctcctctct aacagagcct ttcaattcac tccaatcaaa atgatcccct
    22621 tgcagataat tgccaactgt tgtgttgacc aattcagcac tttctcgtaa aatatctctg
    22681 ctctttttca catagacaaa tccgcgagtg ttgaccttag ccttagagat aatacgtttt
    22741 tcctttttag atactgtgat cgcaacaata aaaataccgt cctctgataa gaccttacgg
    22801 tctctcaaaa caatattgcc aacatcacca atggcatttc catcaatcat cacatcacta
    22861 gcaggaaccg caccctcgtg taagaagcca tcctcatcaa gcaccatgat gtcaccacgc
    22921 ttcataatat gaatattttc aggtagtata ccagcctcct cagctaaatg agcatgagca
    22981 gctagatcgc ggtattcacc ttgaatcggg aacaggtatt ttggtttgac gagattaatc
    23041 atcagctgca ggtcacgcgc attggcatgt ccagaaacac gtaaatgctg cgtgatgagc
    23101 ttaacagagc cacctgcttt atagataagg ttttcaacac gagcaaccat tgcttccttg
    23161 gcagcgcttg gcgttgtgac aatgtaaacc agatctccgt ccttgatttg cacgtggcga
    23221 tgacgcccta ttgccatttt ctgtaggcta ttaatcggct cacccatacg tccagcctcc
    23281 agaacaatca attcgtgatc ctcaaactta gacatatcct ttggcttgat taatagcttt
    23341 tcatcagcaa tcactagctt tttaagacga agtgctgttc tgacaatatt ttcagcgtca
    23401 gtacctgtca gtaccactcg cctgctatag gctgctgcag aatcaaagac ctgctggata
    23461 cgaacaagat ttgaagcgac agctgcaatg ataatccgcc cgtcggcatg agcaatcacc
    23521 ttatccatct cctcgccaac ctcagcttcg ctggcagtct gctcattgct tgtggcattg
    23581 gccgagtcag ctaatagggc taacacccct tcttttccaa tgtctgccaa gcgagctagg
    23641 tctgtctgat agccctcacg cgaagcctgg tcaaacttga aatcacctgt atagacaata
    23701 ttccccttat cggttccaat aaccacgcct aaactttcag gaatagaatg tgttgtctta
    23761 aagaaggaaa ccaagccatc tttaaattca atttctgtgt cactgtcgac cacatggaaa
    23821 ttcttaaatc tcttggtgct attattggcc ttgacaaaca attttgctag ctcgatggtc
    23881 aattctgaac caaatactgg cactggaacc tccgccaaca ggtaaggcaa agctccgata
    23941 gcatcagcat gcccatgact taaaaagact ccctgaacct tgtccttgtt ttcaattaca
    24001 taatcaagac ttggaattac caaatctaca cctagctgtt ctgtttcagg gtatttcaag
    24061 ccagcatcca aaatgaacat ggaatcgtta atctctacta gatagaagtt tttcccgtac
    24121 tcacgtacgc ctcctaatgc aataatgttt atatcagtca tgatactcct ttttttatat
    24181 tagttattac aaacggtcct tactgggtaa gtcgaattac tgtcttgcag ctaagctgca
    24241 ctcttttaca gtatatcata ttttagggct tattacctca aattgccttg agactttctc
    24301 aatcttttca atagattatc aaaaaagcca agggaaggct ttcattccaa tggcttttag
    24361 agtatttatt ttagtcaaaa agctggtaat aatcagcaat ggtcatttga gattttctct
    24421 tctgatcaag gtcttgaatg attttaccat ttttcatcac aatcaggcga ttaccatagt
    24481 taagagcgtc ctccatgtga tgcgttatca ttaaggctgt caagcgatcc ttagctacaa
    24541 aatcatcagt caaggccatt aaggcttggc tggtcttagg gtctagcgct gcagtatgct
    24601 catctaatag taaaagctct ggtcttttta gggttgccat gagtaagcta agggcctgtc
    24661 tttgaccgcc tgataagaga ccagtcggag tctccagatg attttccaag ccatttccaa
    24721 ctcgcttgac caagtcagca aagtctgcca tataatggct aatcctgcgt gatgacaagc
    24781 ctcgcctttc ccctctttgc cttgcaatca aaaggttttc agctactgtc attcgaggtg
    24841 ctgttcccat tttaggatcc tgaaaaacac gtgataggta gctagctctt ttttctgctg
    24901 gcaggtgcgt cacatcatgc cctaaaagct taatttgacc cttgcttaac aatagcgtcc
    24961 cagcaatcac attaaaaagg gttgatttac cagcgccatt cccaccaaga atcgttaaaa
    25021 aatcatgctc ataaatggtc aaggaaacat catctaaaat agccttagtc tcatcaaagc
    25081 cattattgac ttcgacagta gcgtgaatta attcaataat ttttctcatc gtgataagct
    25141 agcctcctta ataattgctt tttttagcac aggcaccatc aggcaaagtg ctaatataat
    25201 ggcactaaat agcttaagat aatttgtatt aaagccaaga gcaataacta ctgagattaa
    25261 aaattgatac aggatagaac caaccacaat ggctatcaag cgctcaagca gggttaggcc
    25321 tgtagaatat aaaacctcac caacaataat actcgcaagg ccaattacaa tcacaccaat
    25381 cccctttgaa acatcagcat agccatcttg ctgactaacc aaggcaccag ataaggctat
    25441 caaggcatta gagatcgcta agcccataag ctccatacga tcagtatgaa tcccaaagct
    25501 cttagccata tcccgattat ctcctgtggc aatataagcc tgaccaatat tggtgtaaag
    25561 aaaatacatt aacaaaaaaa tcaccaatgt agctacaacc aaaccagcta ccaacacatt
    25621 ggtgtcagct gcaaagggaa ggtagtcctg aatgcgcttg atatcatgca agcccaaatt
    25681 ggccctgccc ataaccataa gcataatgga atggcaggag gtcatgacta gtatgccggc
    25741 aagaagtgtt ggtatctttc cttttgtgta taacaggcct gtggcgaagc ctgccaaggc
    25801 acccgccagc atagcagcca gagtagccag gataggattt aaaccgagat tgagcagagt
    25861 tactgctaca gcacctccta aaggaaagga cccttctgtt gtcatatctg ggaaattcaa
    25921 tattctaaag gtcaggtaaa tccccaagcc aagaattccc cataacaagc cttgtgatac
    25981 agatgaaata atcatatgaa ctccttttct attgcttacc tgtaaggtca gaacgcttca
    26041 gcaggtcttt tgagatcata agacctaaat cccttgctgc ctttagattt aaaaatggct
    26101 taccgtcatc aactacctcg acaggaacct ctgatacctc ttttccagcc ataagctgca
    26161 gcacctgcct agctgtctca acccctaatt ggtattgact ttgtgaaata gaagcaagac
    26221 tcccttgctc aaccattgta tcaacacttg agtagaccgg aagctgtgct gcatttgagg
    26281 caacaatcac cgctgaaaaa gcactggcaa tagtattatc ctgtgggata aaaacagcat
    26341 ctaccttctc agtcatcaca gacatggtcg tggtaacctc atttgttgag gggacagcgt
    26401 aagctagaac ctccaagcct tgcttttctg caagagctgt aaagtccttg acctgtgata
    26461 ttgaattgtc ctcactgctt gcataaagga caccgaccct tttgacctga ggggtcatct
    26521 ccttgatcag atcaaccgtc tgtcgaacag gaaccttatt tgataagcca gtaacatttg
    26581 cctcaggcct gtctaagtgc ttgactaatt tagcaccaac tggatcagaa atagctgaca
    26641 tcacaaccgg gatagtcttg gttgctgctg ctaatccttg agctgcaggc gttgcgatgc
    26701 caacaacaat atcgtttgtt ttgaccagct gcttgctcat ggtctgaatc ttactttgat
    26761 ctccttctgc attcataagg gtaatgctga ccttttgctc tggctgatga tgcttcttta
    26821 gctcgtcttt aatgccctgt gcaatctggt caagcgcctc atgagtaacc agctgcaata
    26881 taccaacctt aaccacacgc ttgctggcta actgtggctg ttttttgccc tcttttagca
    26941 ctagcgaagc agcaaccatt aaaaagagtg caatgactgt tacgataaga cctttatgtt
    27001 tcatgttcta cctcttaatt tccattctta ctccgttgct aacatttaga gtactcacaa
    27061 aaagaaaaaa cgcttagtaa tcagctacta ggcgcttttt ttgaaatcca atgtcagcgc
    27121 atagatacct ttttagaagt actctaaaag tcgtatctat gctaacccat aaacacaact
    27181 ttatctatgc cagctttgcc aatttatcat atgctgtgtt tgcttcatct tggatttcct
    27241 ttcttgtttt tttacattat aacctaaaag ctcaaaaata caagagcatt tgaacatatt
    27301 tttccattat tttttgtggt ataatgaaag aattagaact caggagggag aaaccatgtc
    27361 atttgacggc tttttcttac atcatttaac tcaagagctc aaccatagta ttgttaatgg
    27421 gcgcattcaa aaagtcaatc aaccctttga taatgagttg gttctgacta tccgtaacca
    27481 tcgccaaact tacaagctct tgctctcagc tcatccggtt tttggacgca ttcaactgac
    27541 ccaaacagac tttcaaaatc ctcaatttcc caataccttt accatgatca tgcgcaaata
    27601 ccttcaagga gctatcattg aaggctttga gcagattgat aatgaccgca tcatcgaaat
    27661 gaccgtctct aacaaaaatg agattggcga tgccataaag acgacattga tcatcgaaat
    27721 tatgggcaag cacagcaata ttattctggt tgaccgtcat gaaaacaaaa ttatcgagtc
    27781 tatcaagcac gtcggctttt cccaaaattc ctaccggact attttaccag gatcagccta
    27841 tatcgagcct ccgaaaacaa ctgctgtcaa tccttttacg atctcagata tcgctttatt
    27901 tgaagtcctg caaacacagg agttatctgc taaaaatctt caaaagcatt tccaagggct
    27961 tggccgagat accgcacaag agctatccag tctcctgaca actgataagc taaaacggtt
    28021 tagagacttt tttcaaagac ctagtcagcc aagtctaact cagacctcct ttgctccagt
    28081 tgccttctca aacacactga agaccttcca gaatctatct cagctgctag attattatta
    28141 tcatgacaag gctgagagag atcgtatcaa ccagcaggcc agtgacctga tccaccgcgt
    28201 tcaaaacgaa ttggaaaaaa atcgcagcaa actgattaag caagaggctg agctgctagc
    28261 cactgaaaat gcggaggact ttcgccaaaa gggtgagctc ttaacaacct atctgagcct
    28321 ggtgccaaat gaccaggatt cagttgagct tgataactac tataccggcc aaaaaataac
    28381 cattgcactt gataaggcgt tgactcccaa tcaaaatgcc caacgctatt ttaaaaaata
    28441 tcaaaaatta aaagaagctg tcaagcacct ctcaggtctc atcgctgaca cgcaacaaac
    28501 catcgcttat tttgaaagcg ttgattacaa tctatctcag gcaacgattg atgaaattga
    28561 ggacattcga gaagagctta ttcaggctgg ctttgtgaaa agccgtaagc ataacaagca
    28621 ccacaaacgt aaaaagccag agcaatacct ggcttcagat ggcaaaacaa ttattatggt
    28681 cggacgtaac aatctgcaaa atgaggaatt aacctttaaa atggccaaaa aaggcgagct
    28741 ctggtttcat gctaaggata ttcccggcag ccatgtgatc attaaggaca atctaagccc
    28801 aagcgacgag gtcaaaactg atgctgctga attggcggcc tattattcta aagcaagact
    28861 ttccaatctc gttcaggtgg acatgattga agccaaaaag ctgcacaagc caagtggtgc
    28921 aaagcctggc tttgtcacct atacaggaca aaagacacta agagtgacac ctatagaaag
    28981 caagattcaa gccatgaagt gctccccttc agcctcttcc tcataggact acagcaataa
    29041 agataaaaaa agctacagcc tcacacttgg agataggtcc agtcttaaag ctgcggcttt
    29101 tttatcatta cttgttaatc atctctcaaa tcatctaaga agccttgcat atgaatatca
    29161 tctggaacct gctgcaaata cctttttgcc tgcttaactg cttgatcagt atagccgaat
    29221 tcccttaata aataagcata atcctgtaaa aagtcaggat tttcttttag gtctccttcg
    29281 atatctttat agatagtgag ggctttttct tgctgctcca gagcctgata ggccttggca
    29341 agattccatt tagttagcac atgatcaatc tcctcatgct caagagcaat gacctcctca
    29401 aaacgctcca tatccaagta caggctagat aagcgcatga tgacctcttc gtcatcaaca
    29461 gctacttcct tggccctgag caaataccgc tctgagccag ctggatcatg caattcaaag
    29521 gcaagctgtg aagcaagcaa cagcagctgg gggtcaaagg catttttacg cagaccctgc
    29581 tgaactaggc gtaaggcctc ttctgtccga tgctcctcac gcaagctcat ggcatagggg
    29641 tactcgtagc ctaaaaagtc tgcattcatc gtttctaatt gcttgaaata gagattggcc
    29701 ttttggtaag cagcctgatc atataaaatc gtcgccagct caaacactgt ctcatcgtca
    29761 tactcaatgg caagagcctt ttcaagaaac tctacagcag cttcaaattt ccctaaataa
    29821 gcataggcac gccctatgcg ctggtaggtt gagatacctg tcagctcaag aatgtgacga
    29881 ttatcaagcc tagcatattg ctcaatagcc tcgctaaagt gctccagaga catctcgatt
    29941 tcggctaagc caaagatcac tatcggctcc tgactcaatt cagctgcttg aagtagcttc
    30001 tcacgcgcca catcagttag cccctccaaa tcataaagat cagccatgac gagcagagca
    30061 gacaaataat cagcactatc ctctggaatc ctatcaaggt acataaaggc ctcttcaatg
    30121 acattatcct cagctgcaat ctgagcaaga ttaatattga cctccggata agcctcacag
    30181 acctgcaaat aaatcgtctt agcatgcagt aaaaaaccaa tactctctag gtattctgcc
    30241 aaagccaaca aggtctcagc atcgtcctcc tgcaaggctc tttgaaaata gctttctgcc
    30301 tgctctaaat cctgttgctc tagtgaggca atcatttttt cactatttaa catcttcagc
    30361 gaccctctca gcttctgtag gctcttcctc atacaggcct gtaatatcct tgtaccaatc
    30421 aaatagctcc ttcacaacaa ccttaacaga agcataaact ggaatgacaa gaaagacacc
    30481 ccagacccca aacattgacc ctgctgtcaa taataaaaac ataatggtaa tcgggtgaat
    30541 gctcagctta tttccaagca ctagcggcgc gacaaaacgt ccttcaatcg tttgttcaat
    30601 aacaaaaata atcaacacct tgatcagcat caagggtcct tgcaccattc ccataatcac
    30661 tacaggaatc atggctaaaa agctccccag ataaggaatc atattaagaa agcctgcaat
    30721 aataccaaag gtaatagaat agttcaaacc aacaaggcta aacatcactg aaaacatgag
    30781 accaaccaca atcgcaacgg tcacctgtcc ctgcacatag ccagataatt gcttgttgat
    30841 ttctcctaag acacgtgcca taggctggcg cagcttaatc ggaagcacat tgaccaaacc
    30901 atttttcata tggccactgt cacgcagaaa ataaaagaga ataaaaggtg acatgatgat
    30961 tgcaacagta atacgggcaa tagctccagc aaaatttcct gcccaatcaa tagcattttt
    31021 agagaagctt tgcgcataat ctagagcctt ttggctcata ctagtcagca tatcctgcag
    31081 gttggacctg tagctaacca gccattcgtt ttcaagtagc ttattagcct ctagattgac
    31141 cttggcaaca tatttgggaa ggtcttcgac aaagctcctt agctggtctt gaatcatagg
    31201 gataaagcca gaaatagccc agaaaaatag gagaattact aagccaaaga caataaaaat
    31261 agaggctgtg cgatttggac ctagcttctc aaccatatca actaatggct tggtcaaata
    31321 atacaggata gttgagataa ccagcggcag catgataatg gccaaaaatg acaagatcgg
    31381 tgtaaagagg aaggatattt ttgtaaagac aaaaatagtc agaaaaacca gcagcgtgat
    31441 taacaaaacc atcaccgcct gattatttaa aaaccatttg taaaatagac tatcatgatg
    31501 attaggctta gaatgcaatg acattaatgg tatcgtcctt tcttaattgt ggcatcattc
    31561 tgatgagagc ttttaggtta gttgacttaa taaaaggtga ctgttttttc cactagcttg
    31621 ttgtggtcat catacctaaa tttagcagaa aaaaacggcc ggtcttccag tatccacttg
    31681 aaaatgtcgt aatctccctc ccaggttggc ttttccagca cctgatcata gggaacccat
    31741 tctagggtcc cttctctgga ctcctcatca gcaattaagt caccttcaaa gtctgtcacc
    31801 ttaaacacgt aagtatacca atcatgccct ggtgtaaaat caggaaaggt aatcactccc
    31861 ttaaagtcca ttgcttttac cagcaggtga gtttcctcta aaatttcacg tctggcacag
    31921 tcatcaggag attcgcctgg ctctaatttg ccaccaactg aaatccactt accttggtga
    31981 acatcatttt ccttcttgtt gcgatgcagc agcaataaag cctcaccgtt atcaatataa
    32041 caaatcgttg ctaacttagt cattcatacc cttcctttgt ttagttgtta ctattatacc
    32101 aatctctgag aaatatgcca tcattttatc atttaagcac atcaaacaag aaaaccacaa
    32161 tcactacaac tcttagccct gtactagcaa aaaagccttg ataaggcaac gtctgctgac
    32221 tcatcaagac ttatcactat ttaacgaatc acttcctgtg tcttagcgta attggcttca
    32281 actgcttctt tttcggaacg ccaccaatcc tgatgatcag tataccattg gatcgtttgc
    32341 tcaagtcctt ctgaaaaatc agtaaactgt ggctcccagc caagctcctg acgaagcttt
    32401 gtcgaatcaa tagcatagcg taaatcgtgg cctgcacgat ccgttacatg gtcataagcg
    32461 tccttaggct gccccatttt atccaggatt aattccagca cttccttatt atttttttcg
    32521 ccgtcagctc caataaggta ggtctcacca atacgtccct tggtcaaaat ggcccaaaca
    32581 ccagttgagt ggtcattggt gtgaatccag tcacgaacat tctttccttc accatacaat
    32641 tttggcttga taccagacaa gatattagtg atctgacgag ggataaattt ctcgatatgc
    32701 tggtagggac cataattatt tgaacagttt gaaatggttg ccttcacgcc aaaggagcga
    32761 acccaggcct taacaatcaa atcagaggct gccttggttg atgaataagg tgacgacgga
    32821 ttatagttag tatcagcggt gaatttttca cctggcccct caccatgacc tggcaaatcc
    32881 tcacgcagtg gcagatcccc ataaacctca tcagtggaca catgatggaa gcgaatatca
    32941 tatttacgag ccgcctctaa gagtgtataa gtcccaacga agttcgtgta aataaatgga
    33001 cttgggtcat tgagtgaatt atcattgtgg ctttcagcag catagtggac aatagcatct
    33061 gccttagcgg ccagcttatc taccaattca gcatcagcaa tgtcaccaac aaccaactcc
    33121 acgcgatcac ccaaaatctc ctcaaggttg gcacgattgc cagcgtaggt gagcttatcc
    33181 aaaacagtta cgtgaacctc tgggtgatgg ttgtaaacat aatgtacgaa gtttgaaccg
    33241 ataaagccag cgccaccggt aacaataatg tttttatatt cagacatgtt ttttcttttc
    33301 ctttgttttc agctatcagc actcaaaatg cagcttaatc cgacaggcaa gctcagttac
    33361 cagtgaaaac agcgactaag ctgcctcacc tcattgctcc taccatccat aaggtccttc
    33421 ctatcagaag gatacagaga cactcccatc aaaagccata gcttatttca aatgctaatt
    33481 atgataaatc ttcttgtctc aaaggcttaa cggcctctag gaagggatgg cttttatctg
    33541 cttctgaaac ctctgcttgt tcaagacttt cccacgcaat cccaaggctt gggtcagcat
    33601 aattaacaaa ggcatatttt tgcttgagct caagcgccca ataatcattg accagatagg
    33661 tataagccac cttatcagtc agtacttgaa agccattagc aacacctcga gggacaaaaa
    33721 tcccctttga agcgtcaatg actgtttgat aggtatgccc aaagctatca ccctcacgaa
    33781 gatcaaccca agctccaaga accttaccct catcagcaac agagatgtac ttgtcccaag
    33841 gctctgcatg caggcctcga agcacatgct tgcgcgaaaa tgaaatattg ttttgcagct
    33901 tacctgcggc aaaaaactgc tcaggaaagc ctagaggaat cattttttcc ttttgaaaat
    33961 tttccttaaa ccagccacga ttgtcccctc gaacagggat atcaaactcc aaaagtccag
    34021 gaatggcttc aatttcccga caggctaagg ctttatcaaa aaattgttct gtcatcaagc
    34081 ttctccaatc aaccgcagca ggtactgccc gtattcgttt ttcttaagcg actgcgctag
    34141 ctggtagaca tcttctttag tgatataacc catgcgatag gcaatctcct ctaggttggc
    34201 cacctgagcg ttttgcaagc gttgaactgt ctcgatgtat tgggcagcct ccagcaggct
    34261 ttcatgagtg ccagtatcta gccaggcaaa gccacgtccc atcaactcaa ccgataggtc
    34321 gccacgctct aaataggctt tattaacatc agtaatctca agctctcctc tggcacttgg
    34381 tttaatgctt ttagcaatct cgactacatc attgtcgtaa aaataaaggc ctgttacagc
    34441 aaaatgtgac ttaggaactg ccggcttttc ttcgatagaa atggcattca tctcatcgtc
    34501 aaactccaca accccaaaac gctccggatc cttgacctga taaccaaaaa cagtggctcc
    34561 tttttcctta gctgctgcct tttggagcat tttcgtaagg ccgtttccat gatagatgtt
    34621 gtcacctaaa atcaaggcaa ctcgatcatc accaataaac tcctcaccaa tgataaaggc
    34681 ctgtgctaag ccgtcaggac ttggttgctc cttgtaggac aagcttatcc caaactctga
    34741 gccatcgcct aatagctctt caaatcttgg aagatcttgg ggagttgaaa taatcaaaat
    34801 gtctcgaatc cctgccagca tcagtgttga taagggataa taaatcattg gcttatcata
    34861 aattggcatc aattgctttg aagctgcacg agtaagaggg tacaagcgtg ttcctgatcc
    34921 tcctgccaga ataatacctt tcatcgtagc tctcctcatt ttataatacg tcactatttt
    34981 atcatttttt aaaaacagtg tcacttttta tcattaatcc gacgaatata atgatgaatc
    35041 gggtattgac tagtatctaa gctagctttt tgccccaaaa gcagggcaat cagctgctga
    35101 gcaatcaaag gacctagggt caagccagat gagcctagac cgcttgcggc gtaaacacct
    35161 ggtagctgag gtacctgccc aaaaaatgga gaaaaatctc tggtataggc tcgaatgcct
    35221 acgcggtaag aaacatcaga ggcagaactc agcttagggt aataggtcaa ggcctcctgc
    35281 tccaaggcct ctaaaacagc tacatcaggc tcaaggtcat agcccttatc attttcatga
    35341 ctcgctccta cagacaacct atcatgctca aagggaataa tatccagctc cccctctggc
    35401 atgaccactg cgtagttatc tgtagtcaca ttcgcaatgt gataatcaat gagctgtcct
    35461 ttttgcggtc gaatatccac ctgatagcca agtggctcaa gcaattctgg cagccaagca
    35521 ccagcggcta gaatcagccg atcaaagacc ataccatcaa cgagatagcc ttgcttttct
    35581 atgcttatgc caacacgctt tttaaccacc tgatagccac tagcttcaag caaacactga
    35641 cataggtctg ccccatcaac acgtgcagcc ccagaagccc ataccagctg ctcaaaaccc
    35701 tgtaaatcag gaaaatcaac cctaatgtcc gaacgacacc ttatcgccaa atctccaatc
    35761 aaaggcgact cttgcttgcg tctaatggcc agctggtaga gctcctctag cttgtcctca
    35821 ttctttttta ataaataaac accagtctgc ttataaaaat gtgtagaaag cccctctttt
    35881 tgcagctcct tgattaagtc ctgataacaa tctgctccta accgagccag ctggtaccaa
    35941 gccttattcc ttctttttga aaaccaaggg cagataatgc cagcggctgc cttagttgct
    36001 tgaccattac catcatcaaa aatagtaacc tgctgatacc cttgtttttt taaataataa
    36061 gcggcgcttg aacctacaat tccagctcca atgattgcta tcgttgtcat tgccgtttcc
    36121 attctatcat actgcttacc aagcataggc catactcagt catgctatag atgactaaag
    36181 ggatttgttg acgccttgct agccataatg gttacttgcc agccttcctc ttttttccaa
    36241 gcctgcatct tggcaagtag tttatcaata aataaggact cgatgtgatg ccctggatca
    36301 attgccagca ggccttctgt cagcatttcc tgtgctgtgt gataataaat gtcaccagta
    36361 atataaactt gagctccctt agcaagcgct gcctgataaa atttatcacc actgccccca
    36421 caaatagcca ctcgcgaaat caaagggttt tgaccagtat atcgaaccag ccgaaccaca
    36481 tcaagcccaa aggcttcttt aactgtaagt cctaactcct ccaagctttg ctctgctaca
    36541 tttccgacac gtccaatacc atacccatct tgcgtctcaa ccaatacctc tgtctgctca
    36601 atgcccaaca gctcacaaaa ccaatcgttg agcccgtcag agacaatatc tatattggta
    36661 tgactgacat agacagaaat atcgtgcttc accagctcaa ggacaatatc tcgctgtggc
    36721 gaggagacca agtccttcaa gcccttaaaa ataggagcgt gcttggtgat aatcaggtct
    36781 accttggccg caatagcttc ggcaacggta ttttctctca catcaagggt gatcattacc
    36841 cttttgacct ccttatccag agagccaatt tggaggccac acacatctcc tgacatggat
    36901 agctcaagcg gacaatagct ttcatatttt tcgatgattg ttctagcttt catgactgat
    36961 gacctcctca atcgctttta ttttttgaga aatgctagcg cgttcaacag gcttcgttgc
    37021 tggcacacaa gacagggcat agacaagctt atctcgctct ttttgccatt tagccacaaa
    37081 gactgatgac ctttcctgag acaagaaagg accaaagcgc tgctcctgat ctgttagact
    37141 ttgttgacca ggctctgcaa caatgatttc ataatatttg ccattttctg tcatgatggt
    37201 ttcagcacta atacaaaaag cattggcaga tagccaagca cgcagctcat cctctcgatt
    37261 attgggctgt aaaatcaagc gctcaatccc ttgcagcttt tccttaccag ccgctaaaat
    37321 gtcagctatt aaacgccctc ccatgccaca gatggttatg cagtctacag catctctcgc
    37381 ctcaaaggca gctaagccat tagccagacg cacctcaata tgctctgtca aaccatattg
    37441 tgacacattt tttagggctg atacaaaagg tcccttgacc acctcacctg caatcgcctc
    37501 ttgaatatgc tcggtttcaa ccaaaaaaat aggaagataa gcatgatcac ttcccacgtc
    37561 taaaagctta gcaccatcag ggacatagga tgccacatgg cgtaagcgct ttgataaatg
    37621 actttccatt ttcttaatcc ttctaacaac taatcgtatc actattatag caaaatacag
    37681 accaattaaa aagaaagcca catcagacct tctttttacc ataggtagtc ttgtaatagc
    37741 tgcaatagct ctgtactggg caggtatcac acttaggatg cttagccaag cagtgatagc
    37801 gtccaaaaaa gatcaaacgg tggtgggtga tgatccaatc cttcttagga agcttggcca
    37861 tcaaatcagc ttcaatttca gtaacatcgg catctggggc agaaatgttc aagcgcttgg
    37921 caatccttga cacatgcgtg tcaactgcga ttgcagggac accataaatc tctgccaaga
    37981 ccacattagc agtcttacgg cctactcctg gtaaggattc gagctcctta tgggtttttg
    38041 gtacctgacc atcaaactgt gtcagtagct gctgagctgt cttgatgata ttttttgcct
    38101 tatttttata caagccaatt gtccttaggt gatcctcaac atctgacaca tttgcctgag
    38161 ccaaatctga aagctctggg tagctttgcc acagcttagg ggtaaccttg ttgactgcct
    38221 tatcagttgt ctgcgctgat aggataaccg taataagaag ctgaaagggc ttttcttggt
    38281 cccaattcag ctcgccctta gcctctggaa acatctcacc aatgattgat agaacctttt
    38341 ttaatcgttc tcttcctatc ctcattagtt actccaaagg ttcatcgccg caagaaaatc
    38401 atctgaaacc gtcacttcag acgccgtcat atcctctctg gcacgctttt tttcctcaag
    38461 ctgcctgagg cttgtaattc cctccttgcg ccaatttctt agaatagcct gaatatattt
    38521 ccaattggtt tttccattaa agacagcctc tctcagcgcc tcacgcacta aatccagatc
    38581 tgtttggtca tcatgaatgg ttttttccaa atcctctagc tccatcggac tcaaaaaacg
    38641 acccagctca cgctcaaact catcaacaag aagtttcaat tggttggtgt tttgctgttc
    38701 atgctcaccc ttttcatcac gcgccaatag ctggtctaaa gtgactaata caggactagc
    38761 atcaaaaatg atctcaatct ctccagccag ctctatggtt ttcatatcta ataacccctg
    38821 actggtcaag gaagaaatag ccttattcac ctctgctaca gacttaccca aggcattagc
    38881 aatctgacta ggtgccaatt cgtcaagcct agtcgtattt tggagataga aaaactgcca
    38941 aaccaaaaaa tcgtctgagc tcttaaaaat atccttgtaa tgaaacagta aggcagttgg
    39001 aaggaccaaa ttgccagact gataatgctc taaaaaactc ataattcccc tgccaaacgt
    39061 aatagcccaa cctagctttt aatcagtact gccattagca agcactgatt aaccaggaaa
    39121 atgcatcaat accttacaat cgtaatcacc aatagcctga cgaccattca agccgtccag
    39181 ctcaatgaga aaagcgcagc cagcaacaat gccgcccagc ttttcaacca gatcaatagt
    39241 agcctttact gtaccacctg ttgctaataa gtcgtccaca ataaggacac gttggcccgg
    39301 cttaatagca tcagcatgca tggtcaaggt gtctagacca tactcctttt catagctagc
    39361 agaaatcacc tctcttggca atttacccgg cttacgaaca ggagcaaagc caattcctag
    39421 ctcaactgcg accggacagc caataataaa gccacgagcc tccggtccaa caatcatgtc
    39481 aatgtcctta tcgcaggcat attgcacaat ctcacgaata gcatagctgt aggccttgcc
    39541 actagccatt agcggcgaaa tatcacgaaa ggtaatcccc tcctttgggt aattctcaat
    39601 tgaagcaata tattgtgtta aatccatcgt aaaatagtct ttctaatgtc ttttaaatta
    39661 aaatctttcc tattatagca tgaaagtcta aaaaggtaaa tgattcctaa tcatccagat
    39721 caatcccttt ttcctttaaa ttagtcaggc attcctgtaa ataggcctct tgatgctcag
    39781 gataaatcgg tgaggtcagt gccacctcct ctaagtcctc ataggcggca aggctttttc
    39841 ctcggtaatt tttatcctgc cagctcacat ctggctggta gccccgcgcc tgcatttcct
    39901 gcataatcaa caggtgatac tggtaaagct tataaagaga atgggcaaac acatagtcaa
    39961 ccgtcgcatg tggtctcccc cagcctgctc ctcgcaaggc cgcacattca cgatgctgcc
    40021 ccaacaattg ctgccttggt aggcgtgtga ttaaatcctg atgccaaaga cgcataagct
    40081 ctcctatttc tcttcactag tcattaaata ctgataaatc tcctgcggac tgcccaaggc
    40141 cataagctct tgaaacttta ccagctcttt tagctgttgg taaatgacac tgtcagcgat
    40201 gctacgtttt ggggcatcag tctttaccct catcagccca tcttcgatta ctacaaagcc
    40261 taactcctca aaaatttgta tcattttgac caagaggatt ttttcaatct tgaggtaatc
    40321 acttagcaag gtcagcttat ggcgaagatc aaattctggg tattgataga tggtcttata
    40381 aagcttggca aattgctctc tactgccata gcctgttagg taataagggc gcttaatatg
    40441 atttttaaag taaatcgctt caaattcccg atgtctaaaa aggcctttca aggcatcaat
    40501 atcgtcagga acctcatcta tgacaacaac cttggcctgc tggtcctcaa cagctgtagg
    40561 aatatgctca ggtgccctag cagtccttgc tcgaatatca aacagctgca ccccagtcac
    40621 tctagcgtca accagcatta attgcaggct agtatgacct cgccagtgat tgatcgcaag
    40681 actaaccgct aattccaagc cctgtgattg ctggtactcc tgtatcagat gtccctgacc
    40741 aaaggccaag acatcagcct caacggctcc tttgctgacc ttgaacttca agtgactttg
    40801 ttgctgacca atggtccttg cctgcttaat cgtaaaatct tttaagtaaa aaacaggctt
    40861 tttattatcc atgccaaagg gtgctagaag tagcagcttg ttcagactat ctatactcaa
    40921 tgcttctaaa tccaattcac cattgatcaa tagagtgttt ttttcctgac catcgtgtcc
    40981 cttggctgcc acgtattggc aaagtagctc tgatagctcc tctaggcgat cagatggcag
    41041 agtcatgcct gctgccccct catgaccacc aaaggctgta aataagctcc tattgctatt
    41101 aagtgcttca aagatattaa tgctctctaa gcttctggct gagcccttgg ctagcccctc
    41161 atcaatggtc aaaacaagaa cagtctgccc aatctcctcc atgatccgac cagctacaat
    41221 ccctaagacc cctgggtgcc agccagactt agctaaaacc tgcacaggct tgtctagatc
    41281 aagcatagcc attgcttgag caaaaatctc ctgtaccaag acctttcttt cctcattttt
    41341 actactaatc atcaaggcaa gctcatgaag ctcttcgtca tcaaagcctg tcagtagatc
    41401 aatagctgga tttggatcgt caagacgccc tagagcattg agctgcggag caagcttaaa
    41461 gctaataaca tcttcatcaa aatgcgctaa gtcaacctct gaaagcttca tcagctcctg
    41521 caagcctagt ctttctgtct cttttagaac agccagcccg tttttgacaa ggatacggtt
    41581 ttcacctcgt aggctgacca tatcagcaat tgtcccaata gcaaccagat ctaaaaagtc
    41641 tactggaatt gtctctaaca gagctgaagc caacttgaag gcgacgccac agccagctag
    41701 tttttgaaag ggataagcag cagctgggtg ctcagggtga ataatagcaa aggcatcagg
    41761 tagctctgct ggcaggctgt ggtggtctgt tacaataaca tctaccccct gtgcttgcgc
    41821 aaaggcaacc gcttcatggc ctgaaacacc attgtcaacg gtaataatca gcgaaacctg
    41881 ctcttgctcg atgaaatact tgtaaacact ttgattggga ccatagccat ctgtaaagcg
    41941 attaggcaaa taaacaagag gctctgctcc catcatttcc agcgtttcct tgacaataga
    42001 cgccgctgtc atgccatctg catcataatc tccgtagacc aaaatcctct caagcccctc
    42061 aatggcctga cgaatgcgat gaacagcttt ttccatatca tttagcaaat aagggtcatg
    42121 gagctgtgat aggtcagctg tcaaaaagct ggtaagctcc tcttcggtat gaacacctcg
    42181 gtcatagatg agctttgcag ctgtctgact aagtcccttt gcctgagcta gcttaaagaa
    42241 gccagcatct ggctccttat cagctatggt ccactgatat ttggacgtaa tcatttataa
    42301 ttaaatacct ttcttgcaag ataatcagat atagttggaa acaaggtata acacttatga
    42361 gcaagggcta ggctaatagg cagattaatc tctcgtttct tttttcctat tgcagcaatg
    42421 atttttttcg ccacagtatc cgcctgcagc gtaaagcctg caacactggc taaatactgc
    42481 ccgcttgggt cagcctgctc aaaaaaggag gttgcaatcg ggcctggatt aacagttgtc
    42541 acataaacct gcctttctgc cagctccaag cgaagggcat tagaaaagcc aatgactgca
    42601 aactttgtcg cagaatagat acttgacttg gcagaagcta ttaagcctgc cattgagaca
    42661 atattcataa tatgtccaga gccctgctct gccattttgt ggccaagcaa gcgtgcaaaa
    42721 tgaatgctgg ctaagctatt cacacgaaac atggcctcaa tctcttctgc agagaaatca
    42781 tcaaaggcct taaaagcacc aaagcctgca ttgttaatca aaacatcaat cctgccatgg
    42841 cgctggtaaa gctcatcaac aagagcctca atagcagcag ggtcttgaat agcaatctcg
    42901 tagcattcct tattaccgcg agcctgatat agactgtcta acctgtcttt gctgcgccct
    42961 aacaaaatca ggtaatcttc tcttggaagc tgtctgatga tagcctgtgc gagcccgcca
    43021 gaagcacctg ttatcagaat aattctctgt gccattaaat gatcacttcc tctaaatcgc
    43081 gaacaacctt cacattttca aaaatagttg ccgcatcctt ttccatttga cgacagtcac
    43141 gtcctaaaaa gcgtgctgaa acatgattca gtaaaagacg cttagcacct gcatcacgcg
    43201 cgatttgagc agcctgcatg tttgtcgaat gcccatgatt acgggccatt ctttcatcac
    43261 ccttcccgta ggtggactca tgcaccagca catcagcatc ttttgccaat ctaacactag
    43321 cagatgtctt gcgtgtatcg ccaataatgg tgatgatctt tccttttcga ggctctgaaa
    43381 taaagtcctt ggcaaaaatt ttggtgccat cctctagctc aatatcctgc ccatttttaa
    43441 ccttgccaaa aagtggacca aagggcactc ctactgctct aagagcttct gcatcaagtg
    43501 ttccttctaa atccttttga accacacgat accccataca aaagatggta tgtgccaagc
    43561 gctcagcata aacaataaat ttatctgttt ctaaaatctt gcccatagag gtgtcatcaa
    43621 actcatgata atgaatctga taaggcaatt tagagcctga tatcctgatg ctgtttgtta
    43681 cataggattt tatcccaaca ggtccataaa tctcaaggtc cgtctgctcc tcactagctt
    43741 gaaaagcccg actagataaa aagccaggca agccaaaaat atgatcacca tgcagatgcg
    43801 tgataaaaat cttcttgatt tttcgtggct tgattgttgt ttctaaaatt tgccgctggg
    43861 ttccctcgcc acaatcaaac atccacacct cattgatttc atctaatagc tttagcacta
    43921 agcttgaaac gttgcgatgc ttggctggct gcccagctcc agtacctaaa aattgtaatt
    43981 ccatacagtc tattctttct aatgcacaag gtaaatcatg aattctcttt gtgcaaactg
    44041 ataatatttc tttcctttga atgcttggct aagagccaac aattcatcac tattaaagcc
    44101 ctttagcagg gtcatttcgt ttgagaaacg atagatcgtg gttaacaaag catgctcagg
    44161 tgttatgtcc tctggctctc cttgctcaaa ttggcagctc ttcatcttga ttctaccatc
    44221 ttccacataa accacgtatt gtggaaaaat ctgagccagc tccagcagca gcgattcctc
    44281 aggctgcccc tgctcttttt cagcaaaaac aatcgcctcc tgtgcttcat tttcaaagac
    44341 aaagccatag gattgcccca acaaatttaa gcggacaaag ggcttcacct catcaaatga
    44401 cggctctgag gtaaacagct tcaaggccct tgatagctca aaataataat ctgtcgctgc
    44461 ttttggtgat tgcttctgat acatttctgc aaaataagca ttaatcacac ttgggggtgg
    44521 cgtgatggta gctaattttt gctggtctgt caagcccttt aagcaatttt gcaaataaac
    44581 cgtatctaaa ctcgtaaagc ctccataagt ctttgccaat tgaatataat cagtcataaa
    44641 attcttctaa tctccattta tttttgggag caatgtagcc agaaatctct tcaatctcct
    44701 tatcaaagct ataaggctcc aataacgcca acctgttgag gtcatagcat ttgtaggctt
    44761 gatcctgaca gagcttgatc gaaaatggct caaacatgtc ccgaatctga tcaataagca
    44821 actgtcttaa gaggctacga ctgtttttat cacgtgctga cagcctgaca tttggaaaaa
    44881 cagttgcagt caagctagct gtcttatcca tcttgttata aatagccagc cttggaatat
    44941 ccagcatatc taaatctttc aagatgtcta gaacaaccct ctcatgctcc aaatgattag
    45001 ggtcactggc atcaatcaca tgcaagagca aatcaacatg ccgactttcc tctaatgtcg
    45061 acttaaaagc agccacgagc tccgttggta aatcttggat aaagcctaca gtatctgtca
    45121 gagttgcctg aaactgattt tgcagataaa tttgcttggt ggtggcatca agtgttgcaa
    45181 ataattcatc agcctcatat tgcttgtcac cagtcaaaat agtcataata gtagacttac
    45241 ctgcattggt atagccgatc aatccaatat taaagacatc agaggtcatg cggcgatcac
    45301 gaatcgtttg acggtttttt tcgacagcag ctagctgccg ctcaatatct gcaatctgat
    45361 gacgaatgga gcgccggttc agctccagct ggctctcacc cggcccacga ctcccaatgc
    45421 ccccggcctg acgactaagc ataacaccct gtccgaccag tcttggcagc atgtatttga
    45481 gctgcgctaa atgcacctgc aatttccctt catggcttct agcccgcatc gcaaaaatat
    45541 caagaatcag ctgcatgcga tcaatgacct taatacctaa ggcgtcctcc aaattggcat
    45601 tttgccgagc cgttaaacga ttgttaacaa tcactgtatc aatctcattg gcagcaacca
    45661 tttctttgat ttcagccagc ttaccagagc caacaaaggt cttgctatca tagcgctccc
    45721 tcttttgcag atagcaatca acgacctctg cacctgcggt cttggctaga ctagccagct
    45781 ctgtcattga tagctcagca tggtcagctg cttgtaggac cacgcttagt aaaataactc
    45841 tttcctgcct tgcctttgtc tctatcatga acgcgactaa tcctccaaat tccgtagtgt
    45901 ttattatagc atagttttag ctattttcag ctagtttgcc atcgatagct tcctaaggct
    45961 ccttcaaaaa gcgctccacc ctatcatata ttgcctgcgg ataggacgac tcgctaatcg
    46021 agtcaaagcg cactgccata cggttacgaa accaagtcag ctgtcgttta gcaaagcggc
    46081 gtgtttgctg ctttagtgtg gctgttgctt cttctaaact agcctgaccc tgaaagtaag
    46141 ggaagagctc cttataaccg atccctcgac tagcctgaac agctggatac tgctcaaaaa
    46201 gccaccttgc ctcctccaat aggccagaag ccatcatcag atccacccgc ttattaatcc
    46261 gctcataaat aacctctcgc tcatcagtca agccaatgat caaggggtta tagggggcct
    46321 cttgattttc taaatcccta gcaaattgat ttagctcaag tgagcgaatg gcacgcctgc
    46381 ggttaacctg atcaaggtga atgcccttac tagctaatag ctgataaagc tctgtatctg
    46441 tcagtgtctc tagctgctgc cgataagcaa gtagctcctt ttgatcaaga tctcctccta
    46501 gatgatagcc ctctaacagg ctttgcaaat acaggccggt accaccgaca ataatcggca
    46561 gtttaccgcg gctaacaata tcttcaatag ctcgcttagc gtcctgcaca aaatcaaagg
    46621 ctgagtaaga ctctgtcacc tcacgaatgt caatcaaatg atgaaccgca agagcctgct
    46681 ccctggcact agccttagct gtcccaatat caaggtgacg ataaacctgc tgactatctc
    46741 cagatataat ttcaccatta aaggcaccag ccaaggcaat ccctagagct gtcttgccaa
    46801 cagcagtcgg gcctacaatc acaattatct tttcttttgt catttattgt ctttctactt
    46861 aaaaagcagc tgaaaaagtc ttttacttga attttctaat ctttttcgct accatatatt
    46921 ataacataag attgagagac agttatggtc ctcttaatag aaatggagaa tgattatggc
    46981 taaaaaacat ggattcgcaa agggtcttgc tacaggtgtt cttgctactg ctgctaccgt
    47041 tgcaggtgca gtatttgctg ttaaaaagac tattattgac cctgaggaag aaaaagcagc
    47101 atttgtagag gaaaatcgta aaaaagcagc acgtcgtcgt gttgctcgct aatcactaat
    47161 agatgaaaga ttcgacaggc tttatcaata gcctgtcgaa ttttttatgc tgtgagacca
    47221 agctttttgc ttagacacat aaaagaaaca gctcgtcagc gccgcatact gcctacttca
    47281 ttgaccaaca aacagggcaa actaaggcta attttcactg atatgacatg tttcgactat
    47341 aaagcggttt tgtgattgat tgatcacaat atcaaattgc tggtgataag ggtgcagata
    47401 acgagcatat tgagcgcgcc tattgacatg atgaactccg gattgcgacc tctaacgcta
    47461 gtatctctac caagccgcct ttggagctct gtgtcaccat ctgtataaaa gtaaagcgat
    47521 aagtcaaaca actctggctc taaaaaggtt gtcgacatgc cttcagcaat aaggatgggc
    47581 acattcccct tcaccaaaaa agagggagac caaggggtat caatactcaa aaaatccagt
    47641 ccttgcttaa acatcatgat gtcacgcctc agactggcca attcgtgcct agcagggtga
    47701 caggctgtta tactaccaag tacctcctct ccctgatcag ggtagctaat caaaacagcc
    47761 tgactaaaat cattagcgat gatataggca tctgtttcta acaattggct ttgtccatca
    47821 ggcaaaagct gctgtaagcg cttagcaaag gttgatttac cagatgcacc atgaccacta
    47881 attctaataa gcattttctc acgattggct gctgcagtta caatagcttg aagtagcttc
    47941 tccattatct ctcctcatca aataacattc taataatagg acatcattct acatcgaaaa
    48001 acaagccggt ctcccgaaac agcctgactg acagtaaaaa aagattgaag ggcaatccaa
    48061 taaggaaagc ttctccaatc tgattaatag tctataatgg cttaatatga gtgccaaatg
    48121 tcttggttat attgttcaat cgtacggtcc gatgaaaaga agccagcctt agcaatatta
    48181 tgcacaacct ttgtcagcca taggtcctga ttgtcataat cagccagcat ttgttctttg
    48241 actgcaatgt attcctcaag gtcaatcaag gtcataaacc agtccttaga gattaactcc
    48301 ttatagagac ggtcaagacg ttcctcatta ccaagctcta ataattctgg actgataata
    48361 aagttaactg cttccttgat agctgggtgg gcatcataat agtctttaga cacataacca
    48421 cctgtggcat aaagatcaat aatggtatct gaatccttac caaaggtgta gatattatcc
    48481 ataccagcaa gctcagcgat ttccacatta gccccgtcca tagtaccaag cgtcaaggca
    48541 ccattgagca tgaatttcat attaccagta cctgaagctt cctttgaagc tagagaaatt
    48601 tgctctgaaa tatcagttgc aggaatcaaa tgctctgcta ctgtcacatt gtaattttca
    48661 acaaggtgaa cattaaggta tggacttacc tccggatcgt tattgataag ctctgacaag
    48721 caaagaatca aatgaataat atcctgtgca atgatataag ccggtgcagc cttaccacca
    48781 aagataactg ttattttacg cttcggcagg ttgccttttt tgatctctaa gtatttatga
    48841 atcacataaa gggcattcat ctgctggcgc ttatattcgt ggaagcgttt aatttgggta
    48901 tcaatgattg aatgctcatc aagctcaatt cccttattat ccttgaggta gcgctttaag
    48961 gctactttat tatggtgctt aatttcagcc aatcttgcat gaacagcttg atcctcagca
    49021 aaggccatta atttttcaag ccttgtcgca tcagtcaagt aagcatcacc gataagctct
    49081 ttaatatagt ccgccaactc ttggttggcg aattctagcc aacgacggaa ggtaatacca
    49141 ttggttttgt tgttgaattt ttctggatac agctcataga aggccttcaa ttcgctattt
    49201 ttcaggattt cagtgtgaag ggcagcaacg ccgttgacac ttgtggcaaa atgaatatcc
    49261 atatgtgcca tatgcacgcg acctgtttca tcaatgattt ggacagctgg atctgatacc
    49321 cttgcacgaa caagagcatc taattgctcg ataatcgtta ccagctgcgg cacaacctca
    49381 ttaaggaagt caagaggcca tttttccaag gcttctgcaa ggatcgtgtg attggtgtaa
    49441 ccaaccatct tttgaaccac tgaaacagcc tcatcaaaat caaagccatg cttttgtgtc
    49501 aatagacgaa tcaattctgg aatgaccatt gatggatggg tatcattgat ctgcacgtat
    49561 gcgtaatcag ctaagtcatg caggtttgag ccacgctcaa gcgcttcatc gatcaagagc
    49621 tgagcggcat tagataccat gaaatattgc tggtaaatgc gaaggagctc accattttta
    49681 tcagaatcat cagggtaaag gaacagggtc aggtttttgg caatgtcagt cttatcaaat
    49741 gaaatgccat ctttaatcaa gccataatca accccttcaa tatcaaaaag gttaagatag
    49801 ttcttggtgt cacgcttata gcccaaaaca tcaatacggt ctaagcgaga tttcagggta
    49861 aagtttttaa agggaacatc atatgaaatg tcagtcggta ctagccaaga gtcatcctct
    49921 atccaaaaat taggctctgc tgtttgttca ttgtgtctaa agacctgctt gaacaagcca
    49981 caatgataat tcaagccaac cccttcacca ttaatgccaa ggcttgagat agaatcaata
    50041 aagcaagaag ccaaacgacc aagaccacca ttaccaagcg atggctccaa ttcaacgtcc
    50101 tctacctcag caattgattt gcccgcagca gccagctcct ctttgatgtc cttataaata
    50161 cctagattaa tgagattatt agaaagcaac ttaccaatca aaaattctgc tgagatgtaa
    50221 taaaccttac gtttagctgt gttttttgct tttttgcttg cttcttcttt gagataggaa
    50281 agcaacgaaa gatagatttc ctcgttgctt gcacttgcaa gagattttcc taatgtcatt
    50341 tcagtataat ctgtaaagcg tttcatgata tcctcttttc aatatagtat tctagtgatg
    50401 attattggct cgaccgtata gctcagtcaa atggattaaa taggccttgt gctctgcttt
    50461 aatatcgtcc tcaagcatgc gccactgcca gttgccaccg acagtgtttg gcatattcat
    50521 gcggctatca gctgacttat ccagcaaatc ctgcatacac aggatagcag tatcacacac
    50581 agtcgcaaag attgttctta gcatggcctt ggtgatgctt tcagcagctg ccttatggat
    50641 ataatgatta acaaactcaa cctgctctgc gctcaagtgc tcataccagc cattcaccac
    50701 ctcattgtca tgcgtaccag tgtagacaat gcaattgtga tcatagttat gcggcaaatc
    50761 aaagctttga cttgtcacat caaacaaacc aaactctaaa atcttcatgc ccggaaagcc
    50821 agtagatgcc agcagctgct cagccttttc atcaatgtag ccaaggtttt ctgcgataat
    50881 tggcagctca cccaaggcct ctcgaacagc tttaaataga gcaataccag gagctgactc
    50941 ccaatgacca tttttagcag tcacatcacc accaggaatt tcccaaaaat ctgagaagcc
    51001 cttgaaatgg tcaattctaa gcttatcgta cagcttgaag ctctctttga tccgatggat
    51061 ccaccaagca aagcctgttt gctcatggct ctcccagttg taaataggat tgccccaaag
    51121 ctgcccgtcc tcactaaagc catcagcagg tacacctgca atgtaaatcg gctttttatc
    51181 tgcatccacc ttaaagagct ctggcatcgt ccaaacctca acgctatcag cagacacgta
    51241 gattggcata tcaccaatga tagtaatgcc attttgatta gcataggtct tcagcgctag
    51301 ccactgctga taaaagaaat attggcagac cttatgatag gtgatgcctt tggccaacag
    51361 cttgcggtaa tgaagcaagg cagcctcttc acgcttaaca attgctctat cgtcccattc
    51421 ctggagggcc ttgtgatcaa aatgctcttt aatagccata aattcagcaa aatcatttag
    51481 ccagctcgca gttgcttcaa attcggcgag ctgtcttaag ccttcctcag ttgagacaaa
    51541 agcctgaact gctttttcta ataaagggcg tctggcttga aagacttgag cgtaatcaac
    51601 agactccgga tttgagccaa aatcaacagc agcataatca gcttcctgca aataaccgtc
    51661 ctttgccagc aattcaaggt caataaaatg cgtatttcct gcaatagctg aaaaagattg
    51721 ataaggagaa tctccaaagc tagttgttgt taagggcaaa atctgccaat aggtctgctt
    51781 ggtttccttt aaaaagtcaa caaattcaaa ggcctcttta ccaaagctcc caataccgaa
    51841 gcgtcccgga agcgagctga tatgcatcag aataccactt gcacgtttag tcattctttt
    51901 tttctccttg taaaatctta atgttgaaat tataacgcaa ccgtttgcgc aagtcaatat
    51961 cttttcaaaa aaaaagagac tttttcggca tgctagagct gctcaagcct tgataataat
    52021 gagggaagca gctaggacaa aaacaaaaaa aggattggag agacagccta agcagctgct
    52081 cttccatcct catctcactc ctatttggca ttaatatccc tgacactctc tcgctttttg
    52141 aggctaaagg gaaccaaaat tttctgactc agggtttgtt cattggcatt gataatgtct
    52201 aagagctgcc taaaggaggt tcttcccaaa ttttcaacgt taatatcaaa tgttgttaag
    52261 taagggtgaa tcaatttcga atagctagaa ttattaaagg taataatcga aatatcatct
    52321 ggcaccttaa tgtcataaaa ggacaagagc tggaccattc gcaccgacaa aacatcacca
    52381 atcacgatta aggctgtggc cttaaagcta cgtatcgttt caataacctt ttcgatgctt
    52441 attggatcct ttcgatcaaa taacagcatc ggtttgtttt ccaaggataa tttcaagcag
    52501 cccttgagat agccaatata gcgctcagaa gctacctctg cctccatatc gtctgtgata
    52561 aacaggatct gtcggtgacc cttttgatag agatgatcaa ctgcggtttt agccattagc
    52621 tggttgtcat tgtcaatata ggtgattttg ttctcatcac cttctggtgc gccaacaatg
    52681 acaaaaggaa tctggttggt catcaaatag cctctaacag gatcttcttg ctcagaatat
    52741 aatataataa agccatcaac acgcttttgc aggtgcatta acttaacctg gctcaataaa
    52801 tcctcaacag acatacctgt tgcaatggaa acagtgaaat gatgtttctt agcttcattg
    52861 gtaatggtcg atagaatttc cataaaaaag ggatcactca aacgatcatt agtgataatc
    52921 ggcggaaaaa ccaggccaat attatgtgtc aggccactag caagcatttg cgcagctaca
    52981 ttcggaacat agccaagctc gctcatagct cttctaacct tttcctttgt cttttgggag
    53041 atagatcgat tatccttgag gacacgactg acggtcgaag gattaacacc tgcttttaag
    53101 gcaacgtctt ttattgtaac catataaacc tcatttaata cctgataatg acgctatgtc
    53161 aggctttttc acatgtattt tgcttttatt atacaattat ctcctaaaaa atcaactctc
    53221 gccctgcaag aaggcgacat aaaaaactgc tgtcctcatg atcgaaaaaa tgttaaaaaa
    53281 atcaactttt tttaaaaaaa gactagactt tttccgtaaa cggttgcata atattaagtg
    53341 taagaaatat atcttaggag gaaatcgcta tgaaatcatg gcaaaaagtt atcgtcagtg
    53401 gggcaagctt gacacttgct agcgccttat tagtagggtg tgcatctggt tcaaaggaca
    53461 aaacagaaac tgcatcaggt actgattcaa aaacaattaa gctttgggta ccaacaggag
    53521 ctaaaaagtc atacacagat gttgtcgcta aatttgaaaa ggactctggc tacaaggtta
    53581 aggtgatcga gtcagaggat ccaaaagcac aagaaaaaat caaaaaagat gcttctactg
    53641 ctgccgatgt cttttcactt cctcatgacc agcttggtca gctcgtagaa tctggcatta
    53701 tccaagaagt cccagaggaa tacactaaag agatcgctga tacagcaact gatcaagcta
    53761 tccttggtgc tcaatacaag ggtaaaacct atgccttccc atttggtatt gagtcacagg
    53821 ttctcttcta caacaaaact aagctagctg ctgatgatgt tgcttcatac gataccatca
    53881 cgtctaaggc taccttcggt ggtaccttca agcaggctaa tgcttatgct actggtccat
    53941 tgttcatgtc tgttggtaac acattatttg gtgaaagcgg tgaagacact aaaggaacta
    54001 actggggcaa tgaaaaaggg gttgctgttc ttaaatggat ttcagaccaa gcctcaaaca
    54061 aaggatttgt taacttagat gccaacaacg tcatgtctca gtttggagac ggttcagttg
    54121 cttcatttga atcaggtcct tgggattacg aggcagcaca aaaggctatc ggtaaagaaa
    54181 accttggtgt tgctgtttat ccaaaggtaa ctatcggtgg cgaaaccgtt caacaaaagg
    54241 ccttcttggg agtgaagctc tatgcggtta accaagctcc tgctaaggga gataccaagc
    54301 gtatcgcagc cagctacaag cttgcttcat acctaacaaa tgctgaaagc caagaaaacc
    54361 aattcaagac acgtaacatc gtaccagcta acaagaccgt tcaagcttca gaggctgttc
    54421 aatcaaacga gcttgcaaaa acagttatca caatgggatc ttcttcagat tatactgttg
    54481 ttatgcctaa gcttagtcaa atgggtacct tctggactga aagtgctgca atccttagcg
    54541 atgccttcaa tggtaaaatc aaagaaggtg actaccttgc taagctacag cagtttgaca
    54601 aggacattgc agcaacaaaa taagctatct catttataat actatcctaa acaagtacag
    54661 aggtgggcta ttttaacgct atcctttcta ctcatctcta aaggggtgga actaagcatc
    54721 attatttttt cagggcttag tccactccta cttgtttttg atatgacgta aagcttggtg
    54781 ctacttaaat ttttaatcgc ttaaagattt aggtaacact tagctatgtg gtcgttagca
    54841 ccaaacgctt atgaccacag catctgaaca agagagtcag gtaatcctac tttcttgtat
    54901 cctaacataa aggagaacat atatgactca ggcaggctta gcatctcagg ttactgtaaa
    54961 agaggcttta acaaagggaa gcttcgatat taaactatcc gctatcatca tgggctttgc
    55021 caattttgct aataaacaat tcgtcaaagg aacactcttt ttattgagtg aggtggtctt
    55081 tttcatcgcc tttgtttcac aaatcattcc tgctattggc ggcctcatta ccctaggaac
    55141 acaaacacag ggcatgacaa ccaaaactat cgacggtatc agcattcagg ttgctgttga
    55201 tggagacaat tcgatgctaa tgctgatttt tggcttagcc tctctgattt tttgtttgtt
    55261 atttgcctat atttattggt gtaacctaaa aagcgcccgt cacctctaca tgctaaagca
    55321 agaaggggca aaaatcccaa gctttaagga ggattttgtt agtctagcaa atggtcgttt
    55381 ccatatgacc ttgatgacaa ttccattgat tggtgtgctt ctgtttacgg tacttccttt
    55441 gatctacatg atttgcttag catttactaa ctttgatcac aatcacctcc cgccaaagtc
    55501 actttttgat tgggttggtc tttccaattt tggtaacgtg ttaagtggtc gtatggcagg
    55561 aaccttcttt cctgttttct catggacact gatttgggct gtctttgcca cagtgactaa
    55621 cttcttcttt ggtatcattt tagcactctt gattaatacc aaaggcttaa aattgaaaaa
    55681 aatgtggcgg accttctttg tgattaccat cgcagttcct cagtttattt cactgctgat
    55741 tatgcgaaat ctgctaaatg accaaggtcc cttaaatgcc ctgcttagca aattagggtt
    55801 aatccaccat tctctaccgt ttttatctga tccaatttgg gctaaattct ctattatttt
    55861 tgttaatatg tggatcggta ttccatttac catgttaatc gcaacaggta tcattatgaa
    55921 cctgccaagc gaacaaattg aggctgcaga gattgatggg gcaagtaaat tccaggtctt
    55981 caaatcaatc accttccctc aaatcctcat tatcatgaca ccaaacctga ttcagcaatt
    56041 tattggaaac atcaataact tcaatgtgat ctatctctta actggtggtg ggccaaccaa
    56101 ttcagcctat taccaagctg gaaccaccga tctattggtg acttggctct ataaattgac
    56161 tgttacagca gcagattata atctagcctc tgttattggt atcttaatct ttaccgtatc
    56221 agcaatcttt agcttactgg cttacacaag aactgcatca tacaaggaag gagcagcgaa
    56281 ataatgaaaa acaaacgtcg atttcagctt ggattagttt acgccatttt aaccgttctc
    56341 tcaatcattt ggcttttacc tatcgcttgg gttgttctga ctagctttcg tgctgaaggc
    56401 actgcttatg tcgattattt tcttcccaag cacctcacat tagaccatta tattaagctc
    56461 tttacaaatg aaacatttcc ttttgggaga tggtttgtca atacctttgt tgttgctatc
    56521 tttacctgta tcatctcaac ctttattaca gtggcgatgg cttactcgct tagtcggatc
    56581 aaattcaagt ttcgcaatcg tttcttaaag cttgcactag tgctaaacat gtttccaggc
    56641 tttatgagca tgattgctat ctactatatc ctaaaagcac ttggccttac gcaaagtctt
    56701 accgccctag tccttgttta ttctgccggt gctgcacttg gattttacat tgctaagggc
    56761 ttctttgata ccattcctta ttcgcttgac gaatctgcca tgattgatgg ggctactcgt
    56821 atggatattt tctttaagat taccctaccg ctatcaaagc caatcattgt ttacactgca
    56881 ctccttgcct ttatgggacc ttgggttgac tttatctttg cccaagtgat tttaggagat
    56941 gcaaccagca gatatacggt agctatcgga ctcttttcaa tgctgcagcc tgacaccatc
    57001 aatgactggt tcatggcctt taccgctgga tctgtgttaa ttgctattcc aatcacattg
    57061 ctctttatgt ttatgcaaaa atactatgta gagggcgtta caggtggttc tgtcaaatag
    57121 cagtaatgat cacgataacc cttactcaaa aaatccttcc c
//
LOCUS       DARYJX010000009        53540 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYJX010000009 DARYJX010000000
VERSION     DARYJX010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53540
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            127..2313
                     /locus_tag="TU257_000526"
     CDS             127..2313
                     /locus_tag="TU257_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0833565.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2425..3144)
                     /locus_tag="TU257_000527"
     CDS             complement(2425..3144)
                     /locus_tag="TU257_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0833566.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(3750..4109)
                     /gene="rplT"
                     /locus_tag="TU257_000528"
     CDS             complement(3750..4109)
                     /gene="rplT"
                     /locus_tag="TU257_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL0833567.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(4170..4367)
                     /gene="rpmI"
                     /locus_tag="TU257_000529"
     CDS             complement(4170..4367)
                     /gene="rpmI"
                     /locus_tag="TU257_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL0833568.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(4407..4937)
                     /gene="infC"
                     /locus_tag="TU257_000530"
     CDS             complement(4407..4937)
                     /gene="infC"
                     /locus_tag="TU257_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL0833569.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(4952..5074)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(5098..5778)
                     /locus_tag="TU257_000531"
     CDS             complement(5098..5778)
                     /locus_tag="TU257_000531"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL0833570.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(5793..6290)
                     /locus_tag="TU257_000532"
     CDS             complement(5793..6290)
                     /locus_tag="TU257_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL0833571.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            6339..6536
                     /locus_tag="TU257_000533"
     CDS             6339..6536
                     /locus_tag="TU257_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL0833572.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(6523..7011)
                     /locus_tag="TU257_000534"
     CDS             complement(6523..7011)
                     /locus_tag="TU257_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL0833573.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(7056..8279)
                     /gene="pepT"
                     /locus_tag="TU257_000535"
     CDS             complement(7056..8279)
                     /gene="pepT"
                     /locus_tag="TU257_000535"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL0833574.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(8449..9468)
                     /gene="galE"
                     /locus_tag="TU257_000536"
     CDS             complement(8449..9468)
                     /gene="galE"
                     /locus_tag="TU257_000536"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0833575.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(9536..11905)
                     /locus_tag="TU257_000537"
     CDS             complement(9536..11905)
                     /locus_tag="TU257_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0833576.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(11985..13148)
                     /locus_tag="TU257_000538"
     CDS             complement(11985..13148)
                     /locus_tag="TU257_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0833577.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(13162..14646)
                     /locus_tag="TU257_000539"
     CDS             complement(13162..14646)
                     /locus_tag="TU257_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL0833578.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(14650..15891)
                     /locus_tag="TU257_000540"
     CDS             complement(14650..15891)
                     /locus_tag="TU257_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL0833579.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(15875..16231)
                     /locus_tag="TU257_000541"
     CDS             complement(15875..16231)
                     /locus_tag="TU257_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL0833580.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(16236..16925)
                     /locus_tag="TU257_000542"
     CDS             complement(16236..16925)
                     /locus_tag="TU257_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0833581.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(16955..18700)
                     /locus_tag="TU257_000543"
     CDS             complement(16955..18700)
                     /locus_tag="TU257_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL0833582.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(18697..19704)
                     /locus_tag="TU257_000544"
     CDS             complement(18697..19704)
                     /locus_tag="TU257_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0833583.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(19725..20933)
                     /locus_tag="TU257_000545"
     CDS             complement(19725..20933)
                     /locus_tag="TU257_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833584.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(20933..21736)
                     /locus_tag="TU257_000546"
     CDS             complement(20933..21736)
                     /locus_tag="TU257_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833585.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(21736..22671)
                     /locus_tag="TU257_000547"
     CDS             complement(21736..22671)
                     /locus_tag="TU257_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0833586.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(22661..23815)
                     /locus_tag="TU257_000548"
     CDS             complement(22661..23815)
                     /locus_tag="TU257_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL0833587.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(23940..24788)
                     /gene="rfbD"
                     /locus_tag="TU257_000549"
     CDS             complement(23940..24788)
                     /gene="rfbD"
                     /locus_tag="TU257_000549"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL0833588.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(24930..25268)
                     /locus_tag="TU257_000550"
     CDS             complement(24930..25268)
                     /locus_tag="TU257_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL0833589.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(25566..26675)
                     /gene="rpoD"
                     /locus_tag="TU257_000551"
     CDS             complement(25566..26675)
                     /gene="rpoD"
                     /locus_tag="TU257_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL0833590.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(26684..28498)
                     /gene="dnaG"
                     /locus_tag="TU257_000552"
     CDS             complement(26684..28498)
                     /gene="dnaG"
                     /locus_tag="TU257_000552"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0833591.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            28745..29119
                     /gene="mscL"
                     /locus_tag="TU257_000553"
     CDS             28745..29119
                     /gene="mscL"
                     /locus_tag="TU257_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL0833592.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(29345..29521)
                     /locus_tag="TU257_000554"
     CDS             complement(29345..29521)
                     /locus_tag="TU257_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL0833593.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(29676..30488)
                     /locus_tag="TU257_000555"
     CDS             complement(29676..30488)
                     /locus_tag="TU257_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0833594.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(30556..31671)
                     /locus_tag="TU257_000556"
     CDS             complement(30556..31671)
                     /locus_tag="TU257_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL0833595.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(31941..35582)
                     /gene="addA"
                     /locus_tag="TU257_000557"
     CDS             complement(31941..35582)
                     /gene="addA"
                     /locus_tag="TU257_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL0833596.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(35572..38793)
                     /gene="rexB"
                     /locus_tag="TU257_000558"
     CDS             complement(35572..38793)
                     /gene="rexB"
                     /locus_tag="TU257_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL0833597.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(39002..40402)
                     /locus_tag="TU257_000559"
     CDS             complement(39002..40402)
                     /locus_tag="TU257_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0833598.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(40544..42685)
                     /locus_tag="TU257_000560"
     CDS             complement(40544..42685)
                     /locus_tag="TU257_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833599.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(42692..44125)
                     /locus_tag="TU257_000561"
     CDS             complement(42692..44125)
                     /locus_tag="TU257_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL0833600.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(44131..44808)
                     /locus_tag="TU257_000562"
     CDS             complement(44131..44808)
                     /locus_tag="TU257_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL0833601.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(44822..45517)
                     /locus_tag="TU257_000563"
     CDS             complement(44822..45517)
                     /locus_tag="TU257_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL0833602.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(45645..46280)
                     /locus_tag="TU257_000564"
     CDS             complement(45645..46280)
                     /locus_tag="TU257_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL0833603.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(46270..46809)
                     /locus_tag="TU257_000565"
     CDS             complement(46270..46809)
                     /locus_tag="TU257_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL0833604.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(47098..50814)
                     /locus_tag="TU257_000566"
     CDS             complement(47098..50814)
                     /locus_tag="TU257_000566"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL0833605.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            51294..51839
                     /locus_tag="TU257_000567"
                     /pseudo
     CDS             51294..51839
                     /locus_tag="TU257_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            51920..52375
                     /locus_tag="TU257_000568"
     CDS             51920..52375
                     /locus_tag="TU257_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833606.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            52375..52662
                     /locus_tag="TU257_000569"
     CDS             52375..52662
                     /locus_tag="TU257_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833607.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            52655..53203
                     /locus_tag="TU257_000570"
     CDS             52655..53203
                     /locus_tag="TU257_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL0833608.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(53382..>53540)
                     /locus_tag="TU257_000571"
     CDS             complement(53382..>53540)
                     /locus_tag="TU257_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0833609.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT        15906 a        12204 c        10123 g        15307 t
ORIGIN      
        1 tattaaaaaa tcatactaga tttaaactta ttgcaagcat tagctccata tttttggtat
       61 aatttaatct gagattttat ttggagatta tatcttttag gaaaaaatga taaggaagtt
      121 cttactgtga agaattttaa aacatttatc acaagcttta tcaatacaag attaggcttt
      181 gtgctaacgc ttctcttctg cttttggata aaaaccctat gggcttacca tgctgacttt
      241 tcactagatt tgggaaatgc ctatcaggtc tttctaacaa ttattaaccc aatccctcta
      301 gctttgttac tattgggatt taccctttat atcaagaata ctagggcctt ttatatcagc
      361 tcttggatcg tctatattat ccttaacctc ttgttaatat caaattctat ttattaccga
      421 gagttttcag atttcattac ggttagtgct atgctagcca gtagtaaggt ttctgctggt
      481 ttaggagact ctgctttaaa ccttttgcgc atttgggata ttgtttacgt ccttgatttc
      541 atcattctga ttagtttatc agtaactaag accatcaaaa aagacccgcg tccttttaac
      601 aagcgggctt cctttgctgt tacagcactg tcttgcttgc tcttatctgt taatctgttt
      661 cttgcagaga ttgaccgccc ggagcttctg actagaggat tttcaaatac ctatatcgtt
      721 agagcgcttg gattgcctgc ttttaccatt tacagcggaa accagaccta tcaagcacaa
      781 aaagagcgta acggagcaac cgctgaagaa ttagtcgatg ttaagcaata tgtcaagaac
      841 cactacgccg cacctgatcc tcaatatttt ggaatcggta agggaaaaaa tgtcattgtg
      901 atccacttgg aaagcttcca acaatttctt attgattaca agctcaagga tgacgacaag
      961 gactatgagg tcacaccttt tattaattcc ctctaccact ccaatgccac actagccttc
     1021 tctaactttt tccatcaggt caaggctgga aaaacgtctg atgcagagac catgatggaa
     1081 aattcattat ttggcttaaa cagtggttct tttatggtaa attatggcgg cgaaaacaca
     1141 caattcgcca caccatcaat cctagcacaa aatggcggct atactagtgc cgtctttcat
     1201 gggaatgtag gaaccttctg gaatcgcaat aatgcttata agcaatgggg ctatcattac
     1261 ttttttgatt caagctattt ttcaaaacag actgataaaa actctttcca gtatggccta
     1321 aatgacaaat acatgtttag agattctatc aagtaccttg aacagcttca acaacccttc
     1381 tacactaagt ttattaccgt cagcaaccac tacccttaca ccagccttag aggcgaaagc
     1441 agtgaagagg gctttccact agccaaaacc gatgatgaaa ccatcaatgg ttactttgct
     1501 acagctaact atctggattc agccttgaaa tcattttttg attatctcaa ggcgacagga
     1561 ctttatgaca attctatctt tgttctatat ggtgaccact atggtatttc taattccaga
     1621 aatgtcagct tggcagaatt actaggtaaa gaccctgaaa cttggtccga atatgacaat
     1681 gcaatgctcc agcgtgtacc atatatgatc catattccag gctataccaa tggcgggatc
     1741 aaagaaacct ttggcggaga aattgattcc ttaccaacct tactgcatat cttgggcatt
     1801 gataccagca agatggttca actaggacag gatctcttgt cgccacaaaa tagtcaaatg
     1861 gtagcacaaa gaacctctgg aacttatatc acgccagact acactagcta tagcggtcgc
     1921 ctttacaaca ctcaaacagg cttggaaatt acaaaccctg atgagatgac aatggctaag
     1981 gtcaaagaaa tacgagcagc cgttgctcag cagctagcag ctagtgacgc tatccaaaca
     2041 ggagacctac tacgctttga taccgataat ggtctgaaac ctgttgaccc aacaaccttc
     2101 atttatacca agcagctaaa acaactcaaa gagatatcag agaaattagg atcacattca
     2161 accagcattt atagtaaaaa tggcaacaaa tcaactcaaa agctctttaa agcaccttct
     2221 tatctggagt taaatcctaa agaagccgaa aaacctgaat ctacttcgtc ttctgaccct
     2281 aaagaagaat ccgttaagga acaaagtcag tagtggatgt ctaaagcaag cctcactagg
     2341 atcgctctcg tagaagacta aaagcaagct aaaagccttc attgagcgtt acaacttaat
     2401 gagggctttt tagttctgac acttttattg aggaatggcc tcaaagtatt ctggatctgg
     2461 tgtcggttca ggtgttggca caggatctag cttaggctca ggcttcggtt ctggtgttgg
     2521 cacaggatct ggcttaggtt cgggtgtcgg tgctgggcta ttttcttgcg tcacaatata
     2581 acccacataa cagtaatcat caaccttttc ttctggagtg taagtaaagc ttaccccctt
     2641 aaccgtagtc ttagtgacga tatcattgag atgacgtacc acatcaactg cactaacagc
     2701 tgttgtcgca ccaccagcta ccaacaaggc aatcaacaca tagctaccgc ttttcctatt
     2761 tttgtaaata agatagcctg aaacacttag taagcctagc cctactgcca aaccaaccag
     2821 accatctgct gcaccacccg ttttaggcaa gaccttagcg ttagccttag gggtagacat
     2881 cattcctttt ggagatgctg tcactccaca gcttttgtcg taaacaagaa cgtaatgcaa
     2941 tttatcttgg ataggtactt catttggagt gcctttttga atgcctgctt tttgttcatt
     3001 tgtcagatta gaataggctg tataggtcaa atctaccgtt accgtatcag cattagtgtt
     3061 ggcattgaca ttagctgcta gcaaagatag acctaacatc gttgtagctc ccatgtattg
     3121 aaacgcttta gaaaaacgtg gcattataac tattctcctt aatgttttgt agaataaaac
     3181 caataactaa aaaggcatct cctatcatat caatcttatg attattatag gtaaatgtga
     3241 tttttgtaag cactatctaa aaatttcaaa tacactcata tcaatagata ttgaccaaat
     3301 ctcagcagct ttaagcatat cataacaata aatcacctta ttgacacaaa tagaaaggac
     3361 acatttatac ttatcatttt cattctatta tattaaacca tatcttgtgt taaaatacaa
     3421 tgaaattatg acattatggc tcctaaataa gttgttttgc attttattat tttggtgatg
     3481 gatttgatta aaactagaaa tcatatatct ccttatatga tcatcacttg atggactgct
     3541 caactgtctg atacaagatt aagccctttc ttcttagtta acagctacca aagaaaggta
     3601 aattggctcc tttatactaa attagagata gctaaaaaca tctcaaatac tcttgacaaa
     3661 acgtcatgac tgtcttatct agctagatta gctaacataa ggcattaaaa atagacttag
     3721 aaggtttcta agtctacagt cgatctctat tatttgccaa gctttgcctt agcagcatca
     3781 gcaagggctg taaaagctgc tgcatcattc accgctaaat cagcaagcat tttacggtta
     3841 acttcgattt cagcaagctt taggccatgc atcaattgtg aatatgacaa gccattcata
     3901 cgagcagctg cattgatacg tgtgatccat agcttacgga agtcacgttt tttctgacga
     3961 cggtcacgat aagcatagta ataagaattc atgacctgct cttttgcagt acggaacaag
     4021 atatgttttg ctccataata acctttagct aatttcaaaa tacgtttacg acgtttgcgt
     4081 gatacaacgc cacctttaac acgtgccatt aatattctcc ttcaaataac tcttataatt
     4141 ctagtaaata cctgttacaa cccttaatct taaaggccag taaccattgc tttaatacgc
     4201 ttgaaatctc ctgcatgcac catacctgct ttacgaagat gacggcgttg ctttttagtc
     4261 tttccatgga aacggtgtga tgtaaaggca cggaagcgtt tcaaaccgcc tgaacctgta
     4321 cgtttaaaac gtttagctga tgcgcggtgt gttttttgtt ttggcatttt aatattctcc
     4381 tcttaacata tagtgtaata tgacaattac ttcttgtctg aaattggtgc aagctgcata
     4441 aacatttggc gaccatccat ttttgctctt tgctcaataa tagcaatatc ttgagttgcc
     4501 tcagcaaaat cagccagtac cttagcacca atctccttgt gagtaatcat acgtccttta
     4561 aaacggatag aaaccttaac cttatttccc ttttcaagga acttacgacc attacgaagc
     4621 tttgtttcaa agtcaccctt gtcgataact gggctaagac gtacttcctt tacagttaca
     4681 acgctttgct ttttgcgttg ctccttttgc tttttttgat actcaaattt gaactttcca
     4741 tagtccataa gcttggcaac aggaggaaca gcttgcggct ggattaaaac caaatctaca
     4801 tttgcagcat cagctaaaga ctgagcttca gataatggtt taatgcctaa ttgttcacct
     4861 tcaagaccaa cgagacgaac ttcgcgaaca cgaatctcat cattaatgaa tagatctttt
     4921 ttagctatga tcttcacctc tttatttttt tagagaaaaa cgaaagcgga cttaatgaac
     4981 caagcccgca cacataatat cccgtaggaa tttgacatgt agggccagac aacctaggtc
     5041 gcaaggcgag aagctctcac ttctgctttt ctcattattg acattctaac aaataaatca
     5101 tgccatgtca attatttttt ctgctttttc ctgaataaat tggacaacag ctgaaatcgt
     5161 gataccggta gtatcaaaga taatcgcgtc atctgccgcc tttagcggcg aaacttgacg
     5221 atgactgtcc ttataatcgc gtgccgcaat ctcagccttt aaggtgtcaa aatcagctgc
     5281 aatccctttt tcaatatttt cctgataacg acgctgcgct ctttcttcaa cagaagcaat
     5341 caaaaagatc ttcaactcgg catcaggcag cacaaccgtt ccgatatcac gaccgtccat
     5401 gataatagca ccagtcctag caattcgtcg ctgctgattc accagctcct ctctaatctc
     5461 tggcaaggcg gacacccaag aaacattatt ggtgacatca ttttgcctga tcgccattgt
     5521 cacatcttgg tctccaagaa aaaccagttg tgagccatca gctgcttttt taaaagaaat
     5581 tggacgcttt gccaattctt gcaggattag attgacatct tctttgtgat aaccattttt
     5641 taatgcgata taagtcgctg agcgatacat ggcaccagta tctaaatagg tgtagccaag
     5701 atttttggca ataatcttgg ctaccgtact tttcccactt gaggctggtc catcaatcgc
     5761 aattctaatt gctttcatct tttcctcttt aattatttga tattgacctc gtcacctgga
     5821 ttggcatacc agtagccttg ggtcatatga tctgggttta gggcctgtaa ttgctcaaca
     5881 gaaattccag cacgagctgc aatagatgtt gctccttctc ctgctaatac tgtaattgtc
     5941 tttcctgctg cctctgtaga aggtgctgtt tcagtcttag aaggacttgt tgtgtcacta
     6001 gctgctgagc tattagagct cgcttttggc tttgtttttg gttttgagct gaccttcttt
     6061 gttgtctttt tctgagttga tgccccgtaa aatcctgttg tctcattttg cttgttacta
     6121 ccgctgtttg acgtatagaa gaaaataaaa agtatggcaa caataatgac aaagaaaaca
     6181 cttaacaagg cagtcaacca aggtgtgcta atgagtgctc ctcttgattt tcttgttctt
     6241 gtcgccttat tgtcatcaac aattttttct tcccatggtt ctttagccat gattcttccc
     6301 ccttgttaat ttaacaaaat catattagaa taatacctat gaaagtatct atccttccag
     6361 aaaaatgcat tgcctgtggt ctttgccaga cctactctgc tctttttgac tatcatgatg
     6421 atggtatcgt caaattggct cagtctgatg agtcaagtca actcatagat cctaatgatc
     6481 atgatgccat cttagcagta aaatcctgcc ctactaaagc ccttaccctc gagtaagagg
     6541 ctttttttcg tattggtagg cttcaaaata atccagttta atgaagttat ctagtaatat
     6601 aacctctccc ttaaaataag gattaatcgc tagatcatct aaaaaatatt ttttaggcca
     6661 ttttctcatg taaaaaaggt agctcttatc accaacaaat agacaaaccg ttgatttagt
     6721 aacctcaatt ttggtaattg aggcaatcat cagtctgtgc ggagcaaata gctttaaaga
     6781 tacgatcttc aagacaccat tattctcaat tacaaaataa cgatgcaggc caagtcccac
     6841 taatatagca aataaagcaa acaagacaaa aacacgactc ggtatttctg ttctttcata
     6901 caataaggac aggccaataa aaataggcgc aacagcaatt gaccaataaa taatagacca
     6961 agacagctct ggctgccaat gataccttac tttaccgaat aatttaatca tgcttttcca
     7021 tcacctccaa tccgttctga gcattttggg tgatgttaag ccttttggac aatgccaaga
     7081 atcacatcaa ctgccttttc catcgtttgc agactcacaa attcaaacct gccatgcata
     7141 ttttcaccac ctgcaaaaat atttggcgtt ggaatcccca taaaggaaat ctttgagcca
     7201 tcagtaccac cacgaatcgg ctcgataact ggcttaatag ctaggtcctc cataacagcc
     7261 ttagctagat tcacaggtgt catgtccttt tcaatcacct ttttcatgtt atagtactga
     7321 tccgtcactg ttacaaatac acgctctgct ccaagctgac tattcatctc ctcagctagc
     7381 tgtgttacaa aggcctttct agcttcaaag gagctatcct caaaatcacg aataatataa
     7441 gaggcctgtg cttcttctac agtaccagac atgctgtgta ggtggtaaaa gccttgatag
     7501 ccgtccgttt tttcaggacg atcgtcaact ggtaattgac tatggaaatc cattgctagc
     7561 tgcagggcat taatcatctg atttttagct gtaccagggt gaacattgcg acctaacacc
     7621 ttgagctcta gggctgctgc gctaaaggtt tcatattgta gctcgccaag cggacctcca
     7681 tcaatagtat aggcaaagtc aacatcaaaa gcattaacat caaacttatc tgcaccaaca
     7741 ccaatttctt catcaggtcc aaaggcaacc ttaatgtcgc aatgctcaat ctgagggttg
     7801 gcaacaagaa actcaatagc cgtcatgatt tctgcaattc cagatttatc gtcagctcct
     7861 aaaagggttg tgccatcagt tgtaatcagg gtctgtccca aatattggtt gagatttgga
     7921 aaatcctctg ggcataaaga atagcctgac tgaccaagct taatctcccc accctggtag
     7981 ctctcaataa tctgaggggc tactccttct gcattaaaat cagcagtatc catatgcgca
     8041 ataaaaccaa ttttccgagt caatttgctg ctgttagctg gtaagcttcc aatgaggtag
     8101 ccattagctg gattgtaatg aatgtcctgt aggccaatag cttccatctc tggctttagc
     8161 actgttagag caaagtcagc ttgactcttg gtgcttggag ttgtagtgct tgctggattg
     8221 ctccttgtgt tgatttttac atagttcaga aatcgttcta ataaagtttc gtatgtcata
     8281 gatcacctcg ataagttttc gttactatta tagcataaaa ggacctaaaa tacttgccta
     8341 agctcagttt tttacagtgc tttatctgtt ctgttacagt tgcgttctca taaaaagaca
     8401 gctgccaaga aagctcttga cagccttgat tattcatcag cccatgcctt aatcctcata
     8461 accatttggg tgcttgcttt gccatctcca agtatctgta cacatccttt ctaagccgta
     8521 ctctgcagtc cagttaagct cttttttagc cttgctagca tcagcatagc aggctgcgat
     8581 gtctccttga cgccttggta atatcttgta aggaatagac ctgccaacca cctgagaaaa
     8641 ggcttcgata atatctagca cagaatagcc tgtacctgtt cctaaattat aaatagatag
     8701 gcttggctct tcagcaaact ttgcaagcgc agcgacgtgt cctttagcca gatcaacaac
     8761 atggatataa tctctaacgc cagtgccgtc cttggtctca taatcatcac caaaaacgcc
     8821 aacacaatcc agcttaccaa cagctacctg agaaacataa ggtaataggt tgttaggtat
     8881 gcccttagga tcctctccta aatcaccaga ctcatgagct ccgataggat taaaatacct
     8941 taacaataca atatgccact cattatctga tgcatagagg tccttgaaaa tctcctctag
     9001 catcagcttt gtcctaccgt aaggattggt cactgatagt ggaaaggttt ctaaaatagg
     9061 aacggtatgc ggatctccat aaaccgttgc tgaggagcta aaaatgatct ttttacaatt
     9121 aaaggctgtc attaccttta gtagggtcaa tgtgccagag atattattgt cgtagtaatc
     9181 aagtggaatc ctgcttgact ctccaacagc ttttagccct gcaaagtgaa tgacactcac
     9241 aataggatgc ttactgaaaa tatctgttag cagctgttga tcgcgaatat ctccctgata
     9301 aaaggtcact tctcttccag ctatcgaggc aacagcagct aggcttttag gatttgaatt
     9361 gcacaaatta tcaaccacaa caacgtcata gccagcagct agcagttcaa cacaggtgtg
     9421 tgacccgata tagcctgcac caccagtaac taaaatactt cctaacattg attatatacc
     9481 tgactttcta ataattacta atattataac tgattactcc caaaaagtat atctatcatt
     9541 tcattttaaa gaaatcagga taggcattaa tgtagccctt gccttcaata agatcatatt
     9601 ctaacagctt taagtcagag gccacctgct tttgagcagc agttagctgg ctgtcatcgc
     9661 tatttctggt atccaagaca tctgtcaaaa gagcgtagta aggagacacc ttggaatccg
     9721 tatgctctag caataaagag gtaaaatcac tggaattaac acgaggtcta gccaatttgt
     9781 tggtctgatg attgctccag atgaaataat ctgttaaata tttgacctcc tcatcattct
     9841 taaagacctg atctggataa aagccaggta aatgatcacc ataaaacaca actgtaatag
     9901 gcttgtcaac cttttccagt gctgataaaa aggcctttgt tgacttgtcg gtaatgctta
     9961 ataaattcac ataactttgc aggctatccg tctcagactg gtccagtcct gctaggctaa
    10021 catcaacatc tcttagctct gtgtaccaag ggccatgatt ttgcatggta atcactgaaa
    10081 agaattgact tcttttgggg ttaagctggt ctaaaatatt gtcataggtt gactcatcac
    10141 tatagcttga gctcattcgt atcaagtgct ttggcttgtc agctgaatcc tctgtggcaa
    10201 tgaaggtatc aaatcccaat ttgttgtaaa cgatttttcg agagtaattg ttggcgctcg
    10261 caaggtgcaa aacaatccta tccttaggcg aaaaggcatt actaatggca ggcgaaaact
    10321 tcaacttagg aaagacatca gaatacaaaa tcgaaactgt tggattgagg ttatattttg
    10381 gtaggccaaa taggctttga aactccatat tagctgtacc gccgccatag ccatcagagg
    10441 tcattaggcc actcgttgtg gtttccatga tatgatggat ctctgcaata ggatccttgg
    10501 ccaattgaac cccagaaatc ctagctgggt cagcaaagct ctcactcagt atataaatca
    10561 ctgtttgatc agaaatacgc tgatgccttt gcttattgat atcagcagct ctagcttgat
    10621 atttctgata aatcttttgc atagcgctct tgctatagcc tgaaggctga ttaatggtgc
    10681 tggtggtaac ctgcttgaac caaacaaagc tcaaggattg aaaccttgca ttggttgtaa
    10741 gaccatacca gtcaatatca aagacattgt agactgatga cagaactgga ataccttttt
    10801 tgatttcacc atctttattt tggctaaata caaaaaggat agaggcaaat accaaaagga
    10861 tagagcctat tgacatcagt ctaagataaa gcgctgatag gatcttttct ctaaagtatc
    10921 ttttatacaa aacatagatc agcagacccg acaagactag tatcaaaata atactaatga
    10981 tttgagtcag actaatgtaa ttcaagaaaa acttaatctc tttgatccat ttcaaatctg
    11041 aaaacaataa aggctcactt cgctgcttgt atttttcaat attaacaata ctgattaaag
    11101 ctccgatcac cgtattgaca aataaagcaa tgatatagtt gttaatgagc aaaaacacca
    11161 gcacaaaaaa gagggtcaag acaagcacct gaaacagggt tgcacctgga ataatcactg
    11221 ccccatgaaa atcaccatat gctgtgatcc cagcctgaat aaagtaatta aagatgatcc
    11281 ctaaaaataa gctggtcact agagctaatc taagacccca tcgcttgctc aaaacctcga
    11341 taaaggctgt gacgatgagg taataaacca caaacgtcag catataagag caaaagctat
    11401 acttaaagag attcaggcta acaaggtttg actgactatc taaaggccaa taatcatttt
    11461 gcttaatcac agtcttaaat aaagagctgt tcagcgttaa gactgaaaaa gcctgactaa
    11521 gtaaaatgac ttggattcct ctgtttgatt ggtagtcctt cttaaacagg tattttttta
    11581 agagaacccc taaaataagc aggctgacta aagctgccag actgagtagc atttcctgaa
    11641 tcgtacgatt actgatggta aacctgctgt tgtttttatt gatggctaag gtgatatagc
    11701 tattagcaac agcatagtag ctactgacag ctacagaaac aataagcagc tttgaggaag
    11761 catgcttgat cagcaaacat gccattccag ctattaacac taagacaagc cacgaaccat
    11821 aagctccctt atttaacgtg tttttgctta ccgcaaaaat agataaataa agagatgaaa
    11881 ggctaaacaa tatcatatca agcatttcta gatcaactaa ctggcgagct tttgaaatta
    11941 tcttcgttat tataatggtc acaccctttc ctaactgcta aaagctagac attactctct
    12001 gactcagaag cgattacctc tgttactaat tgacgaacag tgacctccca ggtaaagcct
    12061 gaaagcacct gctgatgaat ggcttcttgc aggtcacacc gtttttcttt gtgctcaatc
    12121 aaatgatcca actgcctttt aatatcagag actgtatcat caatgatgat tccctgtgac
    12181 gggctcgtta tcacttcctt gacaccacct ctatctgttg ctaatacagc acatttcaac
    12241 atacctgcct ctaatacagc tgtcggaagc ccttcagcat agatggacgg attaacaaaa
    12301 atatcagatt gagacagcaa agacatggtc tcagcaaaat tcagcttgcc tgtaaagatg
    12361 atggactgat cctctttata gctatctctt agtgaagcaa gcaagggacc atctccagca
    12421 accaccaaga cagccctgtc cttatatgtc agctgctcaa aagcctccag cagcaaaaga
    12481 atcccctttt ccttgatcac tcgacctgca aaggtaataa tgaccttatc ctgcaaagct
    12541 ggtaaataag cctttgactt aaagacctca taaagatcag aatcaactga attgtagatg
    12601 acgcctttgg cttttattcc aaaggtcttg agccatgcca tactgcgctt agacaccgca
    12661 taaaagtcgg gctgataggc tttgacaaaa aaggtaatta catgctcata gactttagca
    12721 aacaagtcta gtagctggtg acctttaaca ttttcgccca cctgaacata gccaccacca
    12781 tgctcgatca caatactagg gatggctttt cttttggcta gcttcaagcc catgaggctt
    12841 gtcaaataaa atcgtgtatt gcagatcaca aagtcaatac gttcttccat cagctccgcc
    12901 agcatgctat gatacagatc attcttatct aaaatcggat agcgctgctt aaatagctgc
    12961 tttgaaggaa atcggtaata agtaatggct tgatctcttt caatagggct cagctggtgg
    13021 ctgttgctgg ttacaatgat gatacggtag cctaggctca ctaattgttg cgctattttt
    13081 tctgtatacc gctctactcc tcctagatga gggcttgtaa agccgctaaa aatggctatt
    13141 gttttcaaag cttttccctt cttatgtata atattgcagc attgttcgag taatcatacc
    13201 taggatcaat agcaacgagc caataagaac ctgtttatta cttaataggc cttgggcctt
    13261 ttcaaggtat ttgttattag aggccagcaa gaccaacact aaagggatca cacccaaaaa
    13321 gtacctatct tgaaccccta gcacattaag gtctccaact ggcgtaaagg tcaaataaag
    13381 gctaaaggta ataccgccta ttattcctaa agacatcaat cccataccaa agcgagataa
    13441 ggtcggcagc tgaagcttgt tggcattagt gatgacaaca gcaaaataat aaaccatact
    13501 aattggcatg agctctacca taccgtatga taaagggcca aacatgtaaa tccctgaagg
    13561 attaaggata tgagccaacg tgtgtcttag cagcataaag ccatatacta tagggttcct
    13621 taacacagtc agtagctgct ctttagcatt gaccttctgg agaaagtcag ccatatccac
    13681 ctgaggtgac ttgatttgac catatacctt taaccaaaaa acagtcacaa ccagcaccgt
    13741 cagaattgac aacagcttta gcagaaacgt gcgagaggct tttgctccaa attgacgtga
    13801 agggataaaa agcagcaaca aaatcaataa aatataaggc agcttagtaa aggtaatgat
    13861 tgagcacagc agggtatacc aaaagagctt ggataaggga atcttttcag ttgtagccat
    13921 ctgaacaaat aaagaaatcg tcagaataat caatccaata gagacacaat cctgattata
    13981 agaaccagca agatagatat tcatcggaag gagacttcct acagcaagca gctgcttgcc
    14041 tgctgtcagc aatcgtaagg caacaaaaac caagatggca taggcaagaa cattacaaag
    14101 cctacctaaa aggtaagata agcccatggt caagcctaag ctccttccaa taaataagcc
    14161 tattacctgt ggtatgtagg caaagttata atagccattt gttgagcgaa tttccttaaa
    14221 tgaaatagcc tcatctgtat ggtctctgct ccacagctga aagcgtaagg gcttgccatt
    14281 gttgtggtcc ataagattaa tgtcatcagt caccagcagc tttgagtcat cattggttaa
    14341 attaagattt ccctcagata agtataaggc tcttgcaaag tgaaccctct catcaggaat
    14401 atcattgatc ggtgagatga aggcagagac agaacccata accacaataa taagcactgt
    14461 cgcatattcc atatttgaag gtaaaaagat aatcaaaagc gcagcaattg caactaatat
    14521 tgctaaaaat ttaatgggta aatccgttga ttgcgtatat aaaagcagca acacaagaaa
    14581 ggcaccaagt aaaacaagca aagccttact cgccttttgc aatttgtcaa ataaggtatc
    14641 taacatatcc tatttccttt tttccataat gtacaagcca tatgacaata gcagccaaat
    14701 catcattgaa attataaaac cataggtaac tccaatcacc ccaaagcttc tagccaaaga
    14761 accagtgatg gctagtgagg agataaagga tacaacataa ggtatcacaa gcaagtgctg
    14821 ctttctgata atggtaatca aattatcaat ataagtggca aaggtgctga taatccctcc
    14881 aaaaataaga agcataaaat caagctggta atgccttaaa tcaataccat aaacaagcga
    14941 tagcaccggc agccccacaa aatagctagc aagcaagata gctaggcttg ctaatagcag
    15001 cactagactg agacgacgct ctaattgtgc aaagctcttc ttgtcctctt ttgaatggta
    15061 aatggccagc tgagtgatca taggccttaa aaacaagaaa atcaggttaa tcataaaaat
    15121 aggcataaac aaaatattaa attctgtttg aacaccggct gggatcagct gctttgagta
    15181 aagctgctcc aaaacaaact tgggctggtt gtagatataa atgagtaaaa aaccatttaa
    15241 aaagagggga aagctctcct tcaatagccc taagatgctt tgagcatcaa tacgacgctc
    15301 aaggctcgta aaggaaactg aaggggttat gtcaaatagc acaatacaag ccactgaaat
    15361 aagacatatc acgatcaaag acaggactag ctgcttggtc agaaccagac agagcgtaaa
    15421 gccaagaatc accagcatat ttcgataaaa caaggatttg ccggcaatat ctaagcgctc
    15481 tctttgttga aacattcctt gaaacacatc agaaatggca tctgtgcaac gatacaagca
    15541 aatcaaccaa atcactagcc ccttaaaccc actatagctc cccaaataaa tatagagcac
    15601 tgaaatggct atcatcaaga aacaggtgac tagtcttgta taaaaatagt ctttgaagcg
    15661 gtacttgtgt aatatatccg ttgattggaa atttctaatc tgaaataagc caatagtaat
    15721 cagctgattt ccaatagcat aggcaaagct aaaggtatct gaagctgatt tagataagac
    15781 ccgagacaca atcatcagta aaatcactga tattagtgct gtcgagctgg ttcccaacac
    15841 attccaaata aaaatcgact gatccgattg aatcctactg ctggttttca tcttcttcct
    15901 gcttttcctt ctcattaagg gctaaatact gaatcatttt tttaagctta atctctgtcc
    15961 gagacaattt ttgagtgata aaaaattggt tgatgatgag taaaaaaatg attgatagaa
    16021 aaacaaaatt tgccggcgat tcaaagccta gcagccttga aaaataaacc gcagcatttg
    16081 gaaacagtga cagcaaaagc actattaaag agaaaaagag ccaaaaaaag ctatcttcaa
    16141 ttaaaatttt ggatctgcga atgctatcta gtataaacat ggctgtcaat aatgcaacaa
    16201 tgatcaaaat cagctgtaac ccaataaaca tcctcttacc tctttctaaa gttttgaatt
    16261 aaaataatcg aaataaacat gtgaaccatg tatttaatag atctagaaag agtgaggtag
    16321 ctttgaccag ccagcctatc attcatttgc acctgaacct cactcaccct atagccttgt
    16381 cgaataagat aagagatcgt atcaggctct ggagtatagt taatattagt tgcaaaaatc
    16441 ctgatcagct cctgattaaa cattctcata ccagaggtcg gatcggtaat acgctttcct
    16501 gtggttagct tgataaaaaa gctaataagg ctattgccta tcattctcaa ggatctattc
    16561 ttttcagcac tgacaaacct tgatccaatg acacaatcag caccagcatt aattgaatcg
    16621 ctcaaagcct caatatactc tggcaagtgt tgaccatctg catcgaactg gagtgcttta
    16681 gcatatccct ttttaaaggc atatttaaag cccgtctgaa tagcaccaga taagccaaga
    16741 ttttccggca aatcaatgat attgtaatgg ttatgatgac agatctctga tgtccgatcc
    16801 gaagagccat cattgataat cacataatca tattgaggaa aatgtctttt gatattttcc
    16861 actacttttt caatcgactc ctcttcgtta tatgctggaa tcattaccaa taagtctttt
    16921 ttcatatcgt caaatattct ctctattcat tcgtctaaac gcgtcttttt agcaatcgct
    16981 ttatgatata acggatagcc ttagctggcc caatcacaat atattttaag gctcctttta
    17041 tacctcccat atagtcaaaa tcgacatagg tatgtggcac actgccttca cgcaggttta
    17101 agagcttatt atcaataaat ggtgtcaata gcttttcatt tcttgaaatt ctaaaatcat
    17161 agtgtctgtc ccaagcaata taaattaaga gacgttcaat ggcatgcagg atcgaatttt
    17221 gagacagagg ctctgctgga atatcagcct cacttaggtc taagtcaaac aagggcttta
    17281 aggcatcgta tttaaaccaa acaaaggtgc catagctcat gacaaaggta tccatcgtct
    17341 gaaaatcaat gcgttttgta agccccattg cctgccaaag ctgattcatt tcaggggcaa
    17401 taaggtgctc attccaagcg tcaacaattt tattaaaacg gaaaaaactt ggaatatctg
    17461 ctatcacaat accgatagca tcagcagcca gtgctgttag gatttgatcc gccggcttca
    17521 ccatcatatc aatcaattca gtgcgccagg attggcccgc ccaaaaatct gcttcctttg
    17581 attttttggt atgaaaatgc ccaatataat catattgaga caatcgttcc tttaaggtca
    17641 gcattggcaa gacatctcga ccgatatttc ctgtcaccaa tatgtcagca cttgccccgc
    17701 tttctcgtag aatttcttta atctcagcct ttttagcctt gctatcggtc gttatgagca
    17761 agtcataatc aaaatgaaaa tgactaaatg cttctaaaaa ctctgacaat aaatcaacat
    17821 aaaaaacatg aagatgaaca gcaattttct tgctttgatc aatgcttatc ggctgctctg
    17881 gcaggtattt atgtgccaga agatacttag catctggtgg atggacctgc gacatatgat
    17941 ccacaatcaa gctggcaggg tatgtcgttt tttggtcaat aaaatccaaa aggtaaggag
    18001 caatgtgctg gttagcgtca atagccttaa ccttgataaa gggcacatgg tgctttaaga
    18061 tggctgtcgg attgtaataa gagaaatccg catgcagcat agaggacgag tcctccttgg
    18121 tcgtatcaaa taccgtcttg tatcgaaagc cagcctccac aaagacagtg gttattctgg
    18181 tttcataatt gtggatcaca tcttgaacgt ctgttagctc aacgatattt tcccaaaact
    18241 gcctaaattc cttactatga acgagggatt ttttgaagct gataaaatag ctctgaatat
    18301 gctctttaaa ggccttggtc gctcgattgt tggtcatgcc ccagaaatca actgcttcat
    18361 ctgcttcata tttgagataa taaggcttca tatcccaaag cggaccaaag caggtatcgt
    18421 tcataatcgt gattgagtca aagtcaacaa ggtgctcaca gcctaaggcc ttcataccat
    18481 catgccaagc tgcaaaatca tagcctttat tgtgtcgttg aataaactga tccatcaaat
    18541 gccgctgttc aagctgctca aggtcctctt gatggatatc actatttgaa ataaagacaa
    18601 tctttgaaaa caaggctctc atctgttcga gctggtaata aacatgatcg cttaccttat
    18661 gatatttatt gaaatgcaca tacaataata gacgcttcat tttttcctcc taaaaagctc
    18721 aagcagcttt gataggtacc tccaacgacg tgaggtaacc acacaattgt attgatgggt
    18781 tagcgcttca acctcttgcc tttgatgatc aagctgctgc tgtagctgat ctatcttctc
    18841 tgcctgtaga gcctcctgat ctgcaagcgt ctgtcgtaat tgatgaatgg tatgacttaa
    18901 ttgatgaatc cgaatttcat ttttagcgtc ctgctttagt aatgcttttg caatagcttc
    18961 catattggct gtagggtatt tagacaaata ggacagctgg gtctccaaca agccttgaat
    19021 acggcccagc attttttcct ctgctgccgg ccttgaatct gaattatccg tcattcgata
    19081 aacagtggtc gaatccttca aataggctag agaggttgac tgaaacagct ctaattgtat
    19141 gtcaaaagtg tcgtctgacg tctccaaatc aatgcgttga ttaactgccc tcatcagatc
    19201 agcctccacc agccaggttg atgacatggt cattcctttt aaagcaagca ttttctcgta
    19261 ggtgtctgtt aagggagtaa agccactttc aaaggcattg ctctgaataa gcttgccgtc
    19321 agtatctaca aaatcaaagt cagtattaga ccattttgaa tctggtgagc tatccagcaa
    19381 atcaacctgc ttttgtagct tgagagtatc agtccaatag tcatcaccat cacatctggc
    19441 aatatactgt ccctttgcct ccaaacaagc cttgacccag gttcttgcaa tcccaagatt
    19501 tacctcatta acgatgagtc gtatacgatc tggaaagctg gcttgatagt ccatgaggat
    19561 ctgtctggaa tagtctgttg aagcgtcgtc aatgacaata atttcaacat caaagctggt
    19621 ctgttgggct aaaaagctgt ctaaggcctc tgaaatccaa ggccccttat tataattggt
    19681 gcaaataata gaaacttttt tcataggatg ctttctaatg acaattattg attaatgagc
    19741 cagctaccat ttctttgata taagccactg gcagagtcca aagcagacag gtcatctgga
    19801 gcaatatcgt ttcgttgaag cacgactaat ggggaatgat tagctgttaa aaagagcagc
    19861 atttgcccgt tttgatcgcg aacagtcacc tcaagcttta atttgatatc atttaggtgt
    19921 gagagctgac actggtagga tatgttctta tgaccaggac cacttgtcgg ttgatcctgt
    19981 gaattgtcat tatataccca aatattgcgg tcaatatcag tcaacgaaaa ggcaacatag
    20041 gtaggctcgt cctttaagac atgataggaa atctcaaagg aaatgggctc atctggacta
    20101 aggcttggct tagaggtcaa cctcacctct aactggcttg ccaaatcaga cacaggctca
    20161 gcagcagctc cttgctcagc atttttcaat tcagtattat caacactgta ttggttagcg
    20221 acatcaaagg gttcgccgta agccttgaca aggccatttt cgatgaggac tgcgcgattg
    20281 cagtattttt tgacagcccc catatcatgg gtcactagta tagtagtctt gccgctctcc
    20341 ttgcgctcca tgaagtagtc attgcatttt cgttgaaagg cctcatcacc aacagctaac
    20401 acctcatcaa gaatcagcac atctccctgt gccttgatag cgacagaaaa agcaagacga
    20461 acctgcatgc ctgaggaata attttttaat ttttgattca tgaaatcatg cagctcagca
    20521 aagtcaacga tatcatcata catatcatca acctcttctg tggtaaagcc cagcattgcg
    20581 ccattcatgt agacattttc acgcccagtc aactcaggat taaagccaac accaagctcg
    20641 atgaaggaca ccattttccc ctcaactgtg acctgtcctt tttctggaac ataaatttga
    20701 gaaataattt ttaataaggt tgattttcca gagccatttc gtccaacgat gccaaaaaaa
    20761 tcccccttat acacgtcaaa gctaatatcc cttagcacat gctgctcggt atagccctta
    20821 atgcctttaa aacggttaac aagagcagta cgaaagctct tggttgcctc tgttggcagc
    20881 ttaaaggact tactgacatg atcaactgtt actgcaattt ctttattagc cattagataa
    20941 tctccgcaaa cttcttagca tttttattaa acactgctac cccaagtgct aataggacaa
    21001 atggaatgag gtaaggaatg atgatatagc accaatttgt cgacatttgc caaatggtca
    21061 cattagctct gtcaatcagc agataccgca aatcttgaat aatctgtgct aaaggattaa
    21121 gcatcaaaat cttggcagca agagggtgtc ggtcaaacac aaaggtaatc gggtagatga
    21181 tgggagtcac atacatacct gcctgcaata gaacctccca aacctgagcc aaatcacgat
    21241 aataaacaaa gacggtagaa agcatcaagg ccacaccaac tgtaagaaca gccagctcaa
    21301 caaagagtgg taaggccaga taagcgtgag gagataaagt aactccattg atagctgcaa
    21361 aaaccaaaac cactaatagg ttgattgaaa agttaatcaa tgctcctaaa actgctgaaa
    21421 aaacgatagt atgctttgaa aaattcaatt ttctaagcag gtctcctcgc gatacaatag
    21481 agaccattcc catactggtt gcttctgaga aaaaggacca aatcacattg gcaagtaaaa
    21541 gagcaaccgg aaaatgagga acgtcaccac cagttcgcaa aaacctgata aacaccaaat
    21601 acatgatggt aaacatcatc aaaggcttta agatagacca caaataacca atagcactgc
    21661 cctgatacct tagtttaaag tctgttttaa caagctcttt caaaagaata cgattctttt
    21721 tactcaataa ttccattatt cttttctcct atagccaaat ttggtcatga tcaatgccat
    21781 aaaaacaagg gtatgaaagg cacgattttt ccgaaagcca tacgctttga aatcagacag
    21841 acgctgatag aaaggcctat ccaaaagccc tacgtaagcc tcaatcaatc ttctgtcagc
    21901 cggatttagc tgcaagtcta gcaattgcct tgcttgatgt tgactagaaa caataagcca
    21961 ccaatacttc tctatgagct tatggggctt acgccactgc ttcagtcgct tagaccaggt
    22021 tcttgcccct aaaacattag catcatgctg acgatagagc tctgttgcca catctagata
    22081 cacaagctct ccctgcgctg ctgcaatcaa ggctaaatac caatcatgca tcaccacatg
    22141 ctcacagctc acccactgct ctgccagcgc gtgattaatc atcatagtgc cgcctgtgac
    22201 tgtgttttca gtcaactcct ggactagctg agtattagca tgatgtgatt gtgtttggat
    22261 catactctca tgacgtactt ctaagtcttg attgaccacc tttaggtctg tgtagactag
    22321 taagggctcg cttatcttgt gcttttgcgc ttctgccaga gtaagctcta atttattgtc
    22381 taaccacaca tcgtcttggt cactgaaaaa ataaatatct gccttttcat atgttaaaag
    22441 ggtgtgaaag cttcgaatca caccgaggtt ttcctgcaca tcagcattaa tcaagcaaat
    22501 tctcggatcc tttttagcaa aagcctgaat gatggcaagc gttttatcag tagagccatc
    22561 atctctgact aataaggtcc aatcctgcac cgtctgcctt tgaatgcttt gtatttgctc
    22621 tgctaaaaac cgcgccccgt tgtaggtaga cattaaaata ttaatcttca tctaaaaata
    22681 aggcctcata ctctcctaca attttctccc aggtatattc tttggcaatg atttgcttag
    22741 ctctttctcc caaatcagca aacgattcct tttgatcaac cctgttaatc agtccagtaa
    22801 ggctgccctt ttcttttgtc caataaaggg ctgctgtttt agcaactgat tgattaaagg
    22861 tcactcccaa aaccaaatta agctgggtat gggctagggc ctccaaaaga cctggattgg
    22921 tacctccaac ctcatgccca tgaatataag caaaagcatg ctcacgaata taagctaaaa
    22981 gctgcttatc atactgtgtt ccaacaaatt ttacacgcgc gtccttatca cagccagttg
    23041 cactaaccag ccgctcaaaa taaggatttt tgtcatggtt gcaaataata accaaatccc
    23101 gctgagtaga tgatgccata aactctctaa tggctgtttc atagttgttt tcaggaacaa
    23161 agcgccccaa aatcaaatag tattggtttt ctgttatctc aaatgtttga aagtaagttc
    23221 tgactttttc atctgatgta gacaaacaag accgccctat ttctgtccca taggcaataa
    23281 aagtcgtttt tgcccaagga taagactttt tgatgtaggc ttcaatgcca atattatctg
    23341 agatgaccaa atcagcatgc tttgtcattt gcttttcggc gtatttcagg tattgctgaa
    23401 caggcttaga ccattttgaa cgcttccatt ccagcccatc aggattaatc aacaaacgcc
    23461 caccacgctg gtgaatctgc tttgcaaagg gggcaataaa gcctccaatg gtattgccta
    23521 gaacataaaa aataggcttt tgaatatgat acctatcaat ataagctaaa gcgtgactaa
    23581 tagccatcat atcataagca atcactctag ctggaccgag cttaggagga ttgatataaa
    23641 aacaatctgc tcccttgtac acaaaatgct ccttgtgctt gctatcgctc aagcaggcaa
    23701 tatgataggt aatgcttttg ttggtctgat tagtgactaa ttcttcaaca aaggtctcaa
    23761 aaccaccata ctttgctggt aaaccgcgac ttccgatgat gaaaacatcc tgcatagcac
    23821 actgccccat tctaaaatat aattagtagt attataccat ataaacaggt cttatgcgac
    23881 ataaaatcca tgaaaagaga gccaatctcc tagatcagct ctttagtgct atcgcttatt
    23941 cattgctgtt gcttgtaaaa agcctccagg gcttcttgcc aggtaggaat cacaaaacca
    24001 gttgccttag ccttatcaag attcatggtt gagttaaagg gtcttttggc tttagcagga
    24061 aaagccgatg aatccacagg cacaacctcg acagctgtct cttttaagat ttctctagca
    24121 aaatcatacc aagtggtgtc ttctttagca tcatttgaca aatgataata gccataaggc
    24181 ttgcgattgt ctgctagatg acacataaac tcagccaagg tcctcgtcca ggttggacgc
    24241 ccatgctgat cattgacgac tgtcaagcga gagtgggtct tagcaaggtt ttgcatggta
    24301 aacacaaaat tcttgccata atgaccaaac acccatgcgg tacgaataat gtaaaattgc
    24361 ttggtatatc gctcaacagc cagctcacct aagcgcttag cacgaccgta tgctgtttga
    24421 ggatcaggag tatctgtttc tagccattcc tgaccagctg gcttttgacc atcaaaaacg
    24481 taatccgttg aaatataaac caaggtcgcc ccgtagcgct cacaagcctt ggcaatatgc
    24541 tcagtaccag ctacattgat agcttcattc agtgcttttc cttcttcttc agcagcatca
    24601 actgctgtgt aggctgcaca gtgatacact aagctaggct tgacctgagc aaaaacctcc
    24661 tctactttag tcgcgttggt aatatccatt tcagcaacat caacagcaac ataatcgacg
    24721 cttcgttcgt ctaaaagata acgaagctct gttcctaatt gaccattact tcctgtaatt
    24781 aaaatcatct tttctccttt gtaaaggtct tatttctttg agctaatcac gcagctcact
    24841 cccatctaat cctaagagag gcttttttga tcagctgacc ctagcaagac ctttgttgtg
    24901 gtatcgtatc agccttgctt tttatctagc taccgaatac ctagggcaat tctcgcatag
    24961 cggctcatct tttcaacgct ccaaacaggg taccagacca actttacctc aaccttggtc
    25021 acctctggaa catctctcat cgcatcatga atatgatcag tcaacaaatc cgccaaagga
    25081 cagcccattg tggtcaaggt catgtcaatc tcggtatgac cattgtcatc aaaacgaatc
    25141 tcatagacca agcctagatt cacaatatca atacctagct ccggatcaat aaccgttccc
    25201 aaagcttcaa gaatccgatc cttgatagct gcaacctgct cttctgtgta ttttaatgtt
    25261 tcagtcatag ctattccttt cacttttttc gaagacctga tatgatgcca agtcaaaaac
    25321 cagcccaaag accagcgcat tcagcatacc tatgatgccc taagctgact aacattgata
    25381 gcctcttttt agtcaccctt acattaacac tagtctttag ctactggcta gcaaaggtaa
    25441 tctcataaac cagtaactag gcttggagtc gttgaccata ggccactcac cgtcaaggag
    25501 agataacgca tttcgggctc gtctcctatt tttagctcgc cgttaaaaag gtccaccgga
    25561 cctttttaat cctcaatgaa gtctctgagc tgcttgctgc ggcttgggtg gcggagctta
    25621 cgcaaagcct tagcctcaat ttgacgaatc cgttcacgag tgacattgaa gaccttccca
    25681 acgtcctcta atgtacgcat tttcccatca tcaagcccaa agcgcaggcg aagaacattt
    25741 tcctcacgat ctgtcagcgt atcaagcact tcgtctaatt gctcacgaag aaccacacga
    25801 gttgtgtaat caacaggatt ttcaatcact tcatcttcaa taaaatcacc taaatgactg
    25861 tcatcctctt caccgattgg tgtttcaaga gacactggct cctgagcgat tttcagaatt
    25921 tcacgcacct tatcaggggt catctccata cgctctgcga tctgctctgg agtaggatcc
    25981 tgccccaatt cttgaaggag gttgcgctgc tcacgcacta gtttattaat ggtttccacc
    26041 atatgcacag gaatccgaat ggtacgtgcc tgatctgcaa tagcacgagt aatggcctga
    26101 cgaatccacc aggtcgcata ggtcgaaaac ttgaagccct tagaataatc aaacttgtca
    26161 acagccttca ttaagcccat gttaccttct tgaatcaaat caagaaattg catgccacgc
    26221 cctacataac gctttgcaat cgacaccacc aaacgcagat tggcctcagc aagacgctgc
    26281 ttagcctcca tatcaccagc ggctactgca accgctaaaa ccttttcctc atcacttgtc
    26341 agcagcggca ccacaccgat ctccttgaga tacatgcgca caggatcgtt gaccttggct
    26401 gaattacttc cgataagctc ctcgtctgtc agctcctctg gcttaggctc ttcaacgacg
    26461 tatttagatg agggatttcc ttccttatct gtaatggaaa tgccaccatc tgtcaaacgc
    26521 tcaagcaaat catcaatttg gtcagcatct aaggtaaatg gaatcacgag tttttctgtg
    26581 acctcatcat cagtagctgt tccttccttt ttatgatgac gaataaactc cgcaatttga
    26641 acgttaaagg ttgtaatttc tttttctttt gccatatttt cctctattcc atttttcttt
    26701 tttcagcaat gaaacgctct aaagcctcta gagccatctg gtggtcaccc ttactgctag
    26761 attccctaat ctgctttcct tgcctatgca gctctctttg ctttagcaat gtcatttgcc
    26821 ttgataaaat atcctcaatc tcaccgctag ctatctcatc aggaagattt tcctctaaaa
    26881 cccggtaata ggcttggtta acctcttcag acagttgcga taggtcatag gaggtaatct
    26941 gccctgtggc ctttagctgc tcatacagcg tctgaagggc tggtgtatca aaataaaaat
    27001 ccggccgatg acgaaattca ttgagcaaat agtcgtgatg aagcaggcga tgcaggaggt
    27061 gactttctgt tttagccaag gctgtcatgc ttttgttaat cggtaaggtc accagagatg
    27121 cctttggttg actagcctgt ccttgttgta agctttgcct atcttgtagc cttaaagcat
    27181 ttaccgattg ctccacctga aaataatcaa aatccggcag caaatcagcc accttattaa
    27241 tatacgaatt ttgtgcggtg attgagggtg cttgagcaat aatctgtgat atatgctcca
    27301 cataagcaat ctgcgattgc aggttatcca tattttcagg cttcaggtga tcaatcaaaa
    27361 actcaacact gctaatgcgc gagtgctgga gcaattctgc tagagcctct ggtgaatgct
    27421 gctgaacaaa ttcatcggga tccattctat ttggtatttt cacgatctcc acttgaaaat
    27481 ctgccagcag ctcaagagac ttggcaatag cattttgccc ggcgtcgtca ccatcataag
    27541 tcaatacaac cttttgtgtc agctgcttga ggtgcctaac atgctctggc gtcaaggctg
    27601 tccccataga ggcaacagta ttaccatagc ctgcccggta ggctgcaata acgtccataa
    27661 agccttccat caaaaagacc tcatgagtct tagcgattat cggcttggcc ttatcaaggt
    27721 ggtaaagctc ataggacttg ttaaatagga ccgtagccct tgaattttta tacttggcct
    27781 gctgcttttc tatatcctct cttgcccaga tacgtcctga aaaagcaatc atattgccct
    27841 tatcatcaca taagggaaac atgattcgat gacgaaaggc atcataaata gcatttgatt
    27901 gttcagaaac atgaaacaag cctgaggctg ttaattgcgc ctcagtatac ttttttgaca
    27961 aggcttgata aaggtagtcc atctcgttag gcgccaagcc aatccgaaaa tactctatta
    28021 gctgatcatc aagccctctt tgataaagat actccttggc tctttggcca atctttgtcg
    28081 tcatcaaaac cgcatggtaa aacttagcag catcttcatg aagatcaatt aaagcctgat
    28141 gagggtgctg cttttgactc aaactagtct gacttggagc aacagtaact gccataccag
    28201 ccttatcagc cacaatctga acactttcta aaaaaggaac ctgccgatat tcctcaataa
    28261 acttaaaaac atcccccgac ttaccgcagc caaagcagtg aaagaactgt ctatcttcga
    28321 tgacattaaa agagggtgtt ttttctttat gaaagggaca caatccaagg tagtgccgac
    28381 cagcccgcga tagatggaca acttctccaa taacatcaac aatattgaca ttatgcttga
    28441 tctgagaaat catctctttg tcaatagcca aaccgtcacc tccccacaaa aagcccattg
    28501 taaatttaca tttcattata ccattgaaaa tgagctttgt aaattgtaaa agcacaatcc
    28561 ttcatcatct aaagcccgct acatcaagca ataagctatg ctaaagtatt gacgtctctt
    28621 atgatcacta gcttgactag cagtacagca ttaagtagct catcagtcct tgataagctc
    28681 ttctattagc ctttttgacc tatttgtgct atgataagat tatctgaaaa aaggggagtc
    28741 aatcatgctc aaagaattaa aagcattttt atttagaggg aatattatcg acctagcagt
    28801 tgcggtgatt gttgggagcg cctttagcgc tattgtcaca tcatttgtca acgacattat
    28861 cacaccgctg atcctaaacc cagccttgaa agctgcaaat gtggaaaaca ttgctcagct
    28921 cgcctggaat ggcatcaaat atggcagctt tctcagtgct attatcaact ttttaattgt
    28981 tggtaccagc cttttctttg tggttaaggt cgctcaaaaa gcaatgccta aaaagggaga
    29041 ggaagagccc gctaagccca aaacaccaac tcaggaagaa ttattacttg acatacgtga
    29101 tttgttagcc aaaaaataac tcaaagctct tacagcagct ggacctgtcc ggctgctttt
    29161 tgatatacaa gcacagagca cttagcgatc aaaagataat agaaccggct ctatttgctg
    29221 ttttagcata tcattgctat ttttatcagc agcaagctaa ggtaaaaaaa gacaaactag
    29281 tatcctcata ctggtttgcc ttcaaactaa ggcagcctac aaagggccgc cttttttatg
    29341 atgattagaa ttttttacgt ttgcgagctg cttctgattt gcgtttacgc tttacagaag
    29401 gtttttcgta gaattcacgc ttgcgtgatt cttgaagagt accagcttta gtaacagaac
    29461 gtttgaaacg acgaagagca tcatcaagcg attcattctt acgtactact gtttttgaca
    29521 tatgtttcac ctcctcaaga tattgtaaca ttttcacgtt ctagcttatc ttacatgatt
    29581 tttcggaaaa agtcaatgat cttttcttga ttttgaggtc attcttaaaa aaatacctta
    29641 aaatttgctg ctgcattagg catcacttgg caaggctatt ctactgcatt tcctgttaat
    29701 aatgctgctt cttgaataaa ggccttgtat ttgccatcct tgtttaattg cttgatcacc
    29761 ttattaatgg tttgccttag gtcatcactc ccctttggca tagctacagc cttagcatct
    29821 ccatcacttg cctgcaattt aaatggtgct aaagccaggt ctttatgttg agctaaaaag
    29881 cctgcagcta ctggtgcttc caaatcaaca gcctgcacct gcccagattt caactcatta
    29941 atagcctcac ccatcacagt tagagaaaca cagttggctt tattaagctg ctccttgact
    30001 aggccctcct cgatgctgcc tttttgaaca gccacctttt tgccaactaa gctatcctta
    30061 ttagcataat gcttggcatc tgacgctttc accaaaatag cattttcagt ttcatagtaa
    30121 gcctcagaaa aatcatacac tttggcacgc tctttggtgt aggacaaacc agaaatcgct
    30181 atatccacct taccagtttg cagactggat aagacattat caaaattcat agcagagagt
    30241 tcaagcttaa cccctagttc atcagcaatg gcctgtgcca gctcaatgtc tgctccgaca
    30301 atagtatcct tgccgtcaac caaggcctta aattcaaaag gagcatagtc agggctaaca
    30361 gcaaccacca gctttccctt ttcctggatc ctgtcttgaa ggctcgtctt gttagcttgg
    30421 ccacaagctg ccaaagcaaa aacagatacc atagcaagtg ctccaactaa taatcgcttc
    30481 atgttcatat tataattatt ccttttcttg ttgatgaatc ttattatatt gcattattat
    30541 tcaatggtca agtttttatt gaatattttt caagcactgc gatagtctgc ttaatcctgc
    30601 ctgtagaacc tgcggctgac agcaatagcc gattctcaca tgatttgctt gattaaagcg
    30661 atttcccgga acgaccaagg taccgtaatc ctccagcagc ctcaaagcaa aggcttccat
    30721 gtcctcatct atatctagcc taacaaaggc cgttgagacc tcattcggtc tatggtagga
    30781 ggccctggct tcacctgtta tccagtcctc taagatagca aggttagtcc tgataatggc
    30841 ttgattgcgc tgcaatagct tgtcagcatg cttcaaggct agcgaagcca ccatatcatc
    30901 aaaaacacct gcacagatca ttgtgtaatc tcgatataac ctaagctgat cacagatggt
    30961 ctcagaagcg gctacccagc caactcgaat gcccggaatc gaaaaggttt ttgacatgct
    31021 attaacagta atccccttat catacaaatc tgccaccgct aaaagatgat cagaggtaaa
    31081 ggaatgataa acctcatcac ttagcaggta aatatcatgc tctctagcaa tattgatgag
    31141 ctcctctaaa taaggcttgg tcatataggc acctgttggg ttgttggcat tgttgatcat
    31201 gatcattttt gtgttgggac gaatcatggc acctagctca ttaaggtctg gcagccaagc
    31261 ctgctcctct ctgatctgcc aataatcaac ctccactcca agagaagctg gaatatcata
    31321 tagctgctga tagctaggat agtgagcaat cacatgatca cctgcttcaa gcagtgcata
    31381 aataaccaaa aaattggcac ctgttgcccc attggtttgc aagatatttc tagctttctg
    31441 ctgctgataa agccctgcca ctgcctgctt aaagtcagga gagccttcta tccagccata
    31501 gtctaatggc ttttgatgca gctgctggta aaaggcttga ggctgctcct gtgttaagtc
    31561 aaagagctcc tcaagcgtta atgaagcaat agatgagcca gcaatatcgt atacagcacg
    31621 tttttcatgc tgatttagcc actcttctac accaaatacc ggtagtttca taagatcacc
    31681 ttatttcttg cgtaatattt attacaatat cgcataaaaa tacaattgtc aaatcaaaaa
    31741 ctatcctttt tttgataaga atcatgtcct atctaacagt tagtcctgat tggtctcgca
    31801 tgaaaggcta ctaaatagag caaaaatcac ataaaaagac tcccaaccca ccaatcagcg
    31861 ggattaggag cctgatagct cgtatcaatt cattgatttc agatcagagt gactatcatc
    31921 actctactat gagccaatga ctaggctagg cggacaactt ctagctgtga tccacccatt
    31981 aataccaagt atttttcgat ccttgcaatc ccgtaggatt ggctcagagc ctcggcatat
    32041 aggtccattt gctgctgata gcgctgcttc agctcagctg actgctgata gcgatctgtc
    32101 ttatagtcaa aaagaacaat acgatcctca aaaagcaggt agccatcaat aataccacgc
    32161 actacgtact gctcctgact taggctgtct tttttcagca tcgcaaaagg agcctcgcgg
    32221 tgtaggcgct ggtgatgctc ttgcaggagc tgccccaatt cagttgtcgc aaaaaaagag
    32281 gttacctttt caatgtcaag ccttgccttg acctctgcgt cagctgagac aagctgtaag
    32341 gtctgttcaa tatcaccagc agtaacctga tcagacattg gaatacgctg catgagctca
    32401 tgcaggcttg agccgacctg gctaggctca acagcctttt tcttagaaaa atcaggaagc
    32461 tcaaaggtct tgggcctatg ataaggctga tctatgatat caacaccatc agtatccatt
    32521 agaggctcat aaagggtttt aagctgactg ggggttctca ccgtcggcag ctcaatggcc
    32581 gcctgatagc ttgcattgag ctctgacacc ttatccagca tgtctaaggc acgcgcaatg
    32641 tcctctgttt gacggttatc cttgagatca tctgcttgca gcagccctga gggccttagc
    32701 tgaccaacag cttctggtgt taagtcactg tcatcaacaa atcgcacatc aataaacaag
    32761 tcctccttgc taaatgttgc tgctatcgct agtagccagt cttgaaagct cagcaatctt
    32821 tctcgactag ctaaggctaa gcgtccttcg gagctattgt cggctgtttt ttcctgtacc
    32881 ttttccttgc tagccttacc aatgaggtat accttttttt ctgctcgcgt catggccaca
    32941 tacaagagac gcatttgctc tgataaggtc gccaagcgta gctgctgctt attgagctgg
    33001 taaggaagag tttccatcgt aaccttgagc gacgccaatt tttcttctct tagaagctcc
    33061 tttacattgg cgacatattt gataccgatt ccctcatctc tatttagaat gattggcgcc
    33121 tgtaggtcag ccatcgcaaa gcgcttgtcg caattcaaaa tgaacacgta atgaaattca
    33181 agtccctttg atttatgaat tgtcatgagg ttaacagcat gcttaggcct ttcgacctca
    33241 acatctgcca aatcattttg cgtctccagc accttatcaa tcatgccaat aaagcgtgag
    33301 agtcccttgt agcctgattg ctcaaattgg tcagcccgta tagcaagggc gtaaaggttt
    33361 gcctgagcct gctctgcctt tggctggctt gctacaaagt caaagtaaaa gcgatcgtta
    33421 aaaatcttcc aaatcagctc ataaagcgaa tgaagctttg caaattgacg ccagtctctc
    33481 aaggtcccat caaaatcagc cagctttgtc atcagctcct gaccgatcag ctctgggtgc
    33541 tcgccttgtc ctctcaagct attgctaagc ttgtcataga aggcttgagg ctgcttttgt
    33601 gagctgcctt gcagtgagat tcttgccagc tgatcctcat caaaggaaaa cattggcgag
    33661 cgcattaagg ccactagggc ataatcattc aaaggattgt tgatgcttct tagcgtatcc
    33721 agcatgacca tcacctcaac tgatttgagg taattttctt ggccaccatc agcaacgaga
    33781 ggaatgccat actgattaaa gacctgaaaa atagtgtcat ttcgtgtgcg tgacgaaaca
    33841 agcagggtaa tatcttcaaa agcaaccttc tcctcgttat agagcctgat gatttcctta
    33901 gccactaaga tgacctcacc tgcggagata ccatcgttag ctaaggcttc ctcggtgcct
    33961 tcttgaactt gatcggtgtc atagagcagc aattgggctc gattgttagg atatggctgt
    34021 ctttgtccct cactgcctgc taccagctgg tgcttgtcat cataggtaat ctctcctaaa
    34081 gactcgtcca taaggcggct aaagacagcg ttggtgacat ttaggacctc tgactgactg
    34141 cggaaatttt cctttagtaa aatcagcttg ccatgctcgg gattgctttg ataatcctta
    34201 aacttttgat tgaagatttg aggatctgct tgcctaaagc gatagatgga ttgcttgata
    34261 tccccaacca taaaacgatt atggccatta gacagcagct ctaataggcg ctcctgcatg
    34321 tgattgttat cttggtattc atcaaccatg acctcatgat aatgaccttg gtaagcttgg
    34381 cgaatatctg gagcctgttg taaaatctca atggcaaaat gagctatatc tgaaaattca
    34441 aaggcatttt cttgcatttt tgcagccaaa taagcctctg aaaagctgat cacaaaggct
    34501 tgcagcacct ccaaaagtgg taagctctcc tgttgataag caaggatagt ctccaagtgc
    34561 ctaaatctta ccagctgctc ctgtagcgat ttgaaaatag ggtatttgtg accggctaca
    34621 gttatatcag ctcctgaagg aagtaaagct gttagctcct gtgctagctg acctagtcgc
    34681 gctttaccgt aaaggctgtc aaaatgcaaa gcccactcat ataagctgtc aatcattttg
    34741 aggtgcttag tgtatttggc agttagcttg ccagccttgg ttgtttgagc gtaaccctcc
    34801 atgtctgtga ggtctcgcag ctgatcagca gtgtcctgca tacaggctaa gagagcatct
    34861 acagcttggt ctggaatatc tgtaaagctg gtataggtct tagaccctcg taaaaagacc
    34921 tctgccaacc aactgctagg attggcagtt gattgactga aggcataaat gctatcaaca
    34981 atctctctaa aggctgagct atccttacga cgtccagaaa aattctgcac cagctgtata
    35041 aaggctttat tgtcagtctg cgacatatag tcttcaaaaa cctgacgaaa gacctcgcgc
    35101 tttaaaatgt cctgctctgc cttatcctgt atgatacgaa aatgcggtga aatccctaaa
    35161 acataaccat gctggtgaac caatttctga gcaaaggcat ccatcgtacc aatatcagcc
    35221 tgtgataaag cctgcaattg gtcattaagg taggccttga gctgataatc ctgagtctct
    35281 gctatagctg tgtgcagctt tttttcaatt ctctctatta gctcagtagc tgcttttacg
    35341 gtaaaggtcg aaataaataa gcaatcaacc ggaatacctc ttagaatctt atccaaaatg
    35401 cgctcaacca taacaaaggt cttacctgag ccagcagatg ctgatactaa gatattttgt
    35461 ccactgctat aaatagcctc aatctgctgc gctgtccgct tgtgcgtctt atctgataag
    35521 gcctcctcct gctgcaaacg agcaatagcc tctggcgtta gaaagccttc atcaatcctc
    35581 atgctttatc tcctcattca ttcgtgtcaa gaaagcctgt ctcctttctt ttgtcggtag
    35641 gacgactagg cgtctcgcgt accctagatc taaatccgcc tcaaagcgcg tgatggcctt
    35701 gagctggtca ccctgaacag acttgccgtc tgcggtataa gggtttatta ggaaatgccc
    35761 tgttttaatc tgcttcaccg cagacaaata tagctgctca ttataagcca gcagggtttc
    35821 tagctcatca gtctcataaa gtgtgttgtt aaggtgatag ctgccattag ccagatattc
    35881 cttggcttgg gctaaaaaaa tgcccttata ggttaactcc ttgtaagccg cagctactag
    35941 ctgatcatca agtgccttaa agtcagacag acttagcctt ggctcttgca tgtgcaggta
    36001 catggcgcca aacaggccct gccccttatt ctttagggca gcaagatagg tcacaagctg
    36061 aggactcaag ccattgtaaa aggcaacaat gtcaaatacc cttgcactgg atttgtagtc
    36121 cacaatgccc agcctaccat cagctagctg gtcaatacgg tcaataaccc ctcgaataag
    36181 cacttgctga cccagcgcta gctcaaaggc ctcctcttgc ttggttatct gcaggccttg
    36241 attaaggtct aagacagagg ctgttgagta agcaatcccc tttaggacct ctaagctata
    36301 tcgcccttca gcatcagcct gataaacctg ctgaaaagcg ctttgctgat taactgctgc
    36361 aatagctgcg cctagctttt ggtcaaaggc agcattagac ctatccttgg ttaccaactc
    36421 aaaaatacgg tgcaggtatt gaccatgaat gcgagcatct gggtgaatag actctggctc
    36481 ttgcagccct aggacatatt tcaagaaata cttgtattga ttgttataaa atacagtcaa
    36541 ggccgatgaa gacagattca agggctgctg acttgaaaag cgggtctcaa taacctcagg
    36601 tgctactggc ttagtagtca aatgatgctc aaaagctgga agacttagct gctcatcggc
    36661 tagcctacgt ttcaaataac gaagggcaac cgtccaaaag tttctgtcct cactggtcat
    36721 gtcatctgca attccctgcc gattaatagc caccaagcga gacaagagag ccttataatt
    36781 gccaatatct gccgctgagt gtgacaaacg gttctttcct ttttcaatga ctggaacacc
    36841 aagggcaatt agctccttca ggtaaggaga gacatcatct gagctattcg ttaagcttgt
    36901 aggcaggctt aacaccagct cctgcgtcgc tgcattaaac agggaaagtg ctgtttggtg
    36961 atttttcttg atattttcaa agctcggcac atcaaggcgc tggtaagagg cagtctgctc
    37021 attgatgctt gccctttcct gatcagagat caggctggtg ttttttgtct gcttaggaaa
    37081 atgggagcga ctcaggccaa tcgcaaacac aaagggcttg gaatgcggct ccaccagatc
    37141 ataggatttg atagacacaa catctaaggt cgcaggcact gtccgataat gtgctgtctg
    37201 catgcccatc ttgatcagag ctagacagtc tgcaagggtc attttttcct gaccaaacac
    37261 ctgataaaag gtctctaaaa tgcctgtgaa ggctttccaa acctcctcgt ccttttccct
    37321 atcagtctcc cttctactgc ctgctagtgc ctcaaaatta tcagccagct gaatggtctt
    37381 aaaaaaggtc attagcttat caagtaggga agcccctagc tgcttttgac tcttaaagag
    37441 ctgctggaga ggagtcacca cagcaagtcg cagctgattc aaaagaggca aaggatactg
    37501 acgtgaggaa tttagggtaa agggtcttga aaatttggtg aagccttgaa tatcagcaaa
    37561 gaccaagtat tgctcaagct gatccagctc tccctcttga aagcgcccaa agagtcctga
    37621 ttttagtaag ttgacaatat cctcacgtcg ccaattgtat ctgcggcctc tttctaagga
    37681 ttcgacaaat tgaaccaagg ggtgagcaga catcggctct tgcttgccga tataataagg
    37741 gatctcaaat ttctcaaaaa taggaccaat ttgcagctga taagacgcca catcacctaa
    37801 aaggacaagc atatccttat agcgataacc ctgatagagc ttctcacgaa tagcctttgc
    37861 aacatgctca agctcctctt tttgattgag cgcttgccag atcacaacct tgctcttgtc
    37921 cttggcactg agctgccaat caagctttga atagtcatga ttggcttcaa gaagctgtgt
    37981 taggcgagaa aatgacacat caaagacctt ttctgacgtt gtgtagatcg gcttggtttg
    38041 aaattgctgt gccagctgtt ggataaacgc aaggctcgcc tcgtagagat ttcccttggt
    38101 aaaggctagt cgataagcct tttgactgat ataggctcca ataacgattt cttcacaggc
    38161 ttcgtttaag agcgctagca gctgctcctc ctcagctgaa aagcgggtaa agccatcaat
    38221 cactaatacg gtctgcctta gctcgtcatc taggctcttg cttttgatag cctcagcaag
    38281 ctgagccagc ctacttgact ggtcgtaatc tccttgtgca atcagctgct cagccttggt
    38341 cataatcgtg atcaggtcct cttgcttttc tggtctatca agcgtcgtta agtcaaaggc
    38401 tgtcagatta gctgcttgca attccttata tagctcaact aactgggcaa taaaggcctg
    38461 atctgtccgt agccggtgaa aaacctttag ctcatcttct tgcagctgca tgagcacacg
    38521 ataaaaaatc atggctaagc cattatcatc taacgcttgt cgattagctg ccttagctaa
    38581 ggtaaaataa cgcgccatct gctcaaagcg ggtcaccgta atagcaaagg aaccctgctc
    38641 tggcaataag gctaggacag aacgttcctt ttcaaaggat agagagttag gagcaatata
    38701 aaagacacga tagcccttat cagcataagc tcttgcctct ttgactaaaa tctctgtcat
    38761 ggaatagcta atctctgtgt atagtaattt cataaaactc cttttatttg gacctgatac
    38821 aacgtctatg cctccattat aacaaatcag ccttgctttt cccattgtta atgatctttc
    38881 aaacgccaca agaagcgctc acagcatgaa aaaagcctac catttcacat ctgctgcttt
    38941 gcgcaagaaa tgataaggct ttgtcttgta taggctcaaa aaacagacta agagctccta
    39001 gttaagctgc cctgtgcttg tctcttgtga tctgtcccca ggcattcttt ttacgctgat
    39061 aaccaataaa gctgctcacc ttgataaggg ttaataccgt atgaagaaca aggcattggt
    39121 agatggcagc atagattacc caagccatat caaaaagagt aatgctacta ttgttttgca
    39181 aataaaccct atttaaaaac gatgtcaacg caataagcac acaatagcaa atatagagca
    39241 gcatcagtga cacaaaaaag gttgtgttta attgatggca tagcaaagac agcacaatga
    39301 taataacacc aaatgcctca ataaaaggag ataaaagctc aaacaaaaga tacagcacat
    39361 aggaaatgag taccgtcgct ttaaaccgac agcttacaaa aaactggaga tactttttca
    39421 agcattgata cagtcctaaa aaccaacgac gcctttgccg acacaaatcc ttcaagcgac
    39481 tgggcgcttg gctccagcaa atagcgtctg tttcatagcc aatacgataa ggaatcttgt
    39541 tgttatggca gaaaaaatgt aatttcatca ccagctccat atcttctccc agagtcccag
    39601 tgtcataacc atcaacagca atcgcaagct cttttttaaa cagtccaaac gctcctgata
    39661 tgattaaatt cccagcagcc tggtctaata aaacacgagc tccaaaaaag gcacaatcat
    39721 actcaattgc ctgcgcacac gaaataagct gacgcggcaa atggtagtct acgatcctcc
    39781 cagctgccaa tgctactccc tgcgaaacct tgaccatgcc cccaacagca atgacagacg
    39841 gatcctttgc agcagtcttt gcaatacgct taagcgaatc ctcctgtagc atcgaatcag
    39901 cgtccatgca caataaataa tcgtattgag cagcgttaat cccaagattg aggctatctc
    39961 ctttgccgcc atttgccttt tcaagcaggg tcagcttgat atgcttgagc tgcttttggc
    40021 ttacagcctt tagagggcgt gttgggatcc gctgattaat cgaacaagtc accgcttcta
    40081 aatgaaactg ctccttcaag agcttggcgg tatgatctgt tgacccatca tcaatgacaa
    40141 taatctcata gcagtcataa tcaagcatca gcaaggactc cactgtttcg ataatggtta
    40201 gctcttcatt ataggccgga accaaaatag acactggcgg taaagaaaca tcaccaccaa
    40261 caggcgcttg ctgtcgcctt tcataaaggt gaatagtccc aacaattaag gatagcagta
    40321 aaaagctcgc ataggcaatc aaaaacgcta aaaaaagata ttgggagtat ttcaatacta
    40381 aaaacagtag ctgcactatc attctccttt aacatgcaat cacttgtgct taccattcgc
    40441 cttacaaaag cgtctcaagg tctgcttcat caaatacccg atattaaagg caaggatcgc
    40501 taagcaaacg attatataaa aaaacaacag gtaataaatc atcttatctt ctcctctttt
    40561 cctgccagac agcctgcacc tgctgatagg aggtctttaa aacttctctt acccttggac
    40621 gctcccagct caacagtgga tactctacca ttgcaatgac ctttgattcc tttagcggtg
    40681 caaaaccaat agctattgct tcaatggcta attcctcaac accatagtgc tcaaaataat
    40741 catcgtgtat tttgtttgaa gctggatcag aaaaattgag cagctgccag ggaatcctaa
    40801 gctcaatcag acgctcgcca aaagaaatat cggtctgcga atcaaaatga gccgagcctc
    40861 gtttgccatt gccctgtttt aattggccgg tagggtagcg cttcagtcct ctttttgcaa
    40921 tcggaacctg atcaatggct gcaaaaatac catcatttct caccaccata tcaaccatag
    40981 taaatcttgg cgtatgcttg ttagggggaa agacataaaa gtcctttcca ttaatctgcc
    41041 taaggtaatt ggcatcagta gcatggtagc gctcctgcac caagaggcga ctgcctttgt
    41101 ggtcatcaac aacaagggca aaatcagcaa agcgatcaaa ccgagcgcta aagccttcaa
    41161 taaccctgct gcctgttttg ggcgtaatgt ctaagggaat gagccactgt ctttgtaagg
    41221 gctgcttttt tgtcgattca atagcaatat agaggtattt ttcgtcctga tcaacgagga
    41281 gctgctgccc atttttcttg taggttagag ctctagacca ctcatctgct gccttttgcc
    41341 catcaatagc atgcgtcctt ggagcatgct caaaggttaa gagaccataa ccttgagcct
    41401 tagactgaac atcaccccaa agaaagcttt gatgtttatt ggttgcaaag gaggtattcc
    41461 agctcctagc agtccaatcg tcctgccagc tatggatcgt tgcaccacag cagccagacg
    41521 caataaaggc tgtgtaatct gccatcaagc gctcgccttg atccttttct gtcaaagggc
    41581 tggaagtcga tatcatttgg tccacacctc tggctgtcga atagccatag cccgtcacaa
    41641 ccactgggac acgatgatag ctcgtcagta gcttgacgta tccctgatat aagggcatgc
    41701 gcttaatatc cccaacaagc ctatcagtaa gccctagacg gtcaaatagc agataatccc
    41761 tataagccga gtgacaatcc aagagcttat aggaagcaaa aagaccggcc ttaaccttag
    41821 cgctgggctt aatattttca atcgtcagtt gaacatattt tgctgcctga gaggcaaagg
    41881 gatcctgata gacaaaggga tctgattgag gcgtatttga aaagctcacc aagtgctgcc
    41941 agccatattt gcggctctcg tatgacgtga tttcctccat gatttcagcc agtatagcct
    42001 caaaccgatt ggcctgaggt gtcgttgcat aataccttcc cttaaagcct acaggcttgg
    42061 cgtgattctg atgattggta taggctatcg tcccactgta ccaatcatca ccaacaatat
    42121 agccgagtag ccatttactc atatcctgat cataatgctg aagccctaaa tccgaatgcc
    42181 agatccgttt tctcccatga atcacatcaa cactagccct agcttccctt aacagagtgc
    42241 ctaaataagc cttatctaag gcgctgatag aagaattgtc atgataagca tctattctaa
    42301 agccctgtaa taggtacaga ggatgacttg ctctgtcatt gtagcgtctc aaagcatggt
    42361 aaaaagtgac gggcataata acccttaccc tgatcgtatt tgcacccata gctgctattt
    42421 gcttgaacca cctatagtag gttttctcat caacgctaag gtctcgtcga cgatagcctg
    42481 ctatggaact ctccacatca acacccttga tgagataagg agatcccttt tgatcatata
    42541 tgcgcttgtc cttggtgtaa aagactgtcc gaatagctga ctggttagag accggcaggt
    42601 acaagcgacc atcaatatca caacaataat agctcaagcc aatcacagac aagagcaaac
    42661 caacaaagat taaatatttc ttcatcacta cctactccaa taatgtattg gtatttttag
    42721 acggtgcact gtactgatag agcgtctcaa tatgcttatc cagccatcgc ccacgacgtc
    42781 taataaagtc ctttagttgc ttaacagagg cctcatagct actgtagtta cgactggctg
    42841 gcacaaggta attagtggca tcgcttcttg atggcactgt aaacacatag ccccacttat
    42901 gataattgcg ctgaatagcc ggacctaaaa aagcaaccgt agcatcaata tacttgatca
    42961 aataatccgt tgataaaaca ttctgtcgga gctgatgata ccttgtgacc accagcttaa
    43021 caaagctagg atcctttagc agcatgcaaa accaaggagc atctgatagg gtaaagtccg
    43081 cctcatcata aggagcctca atctgattat caaaggcgtt gttaaaatcc cagaccacca
    43141 gcttgagctt atcgcgcaaa tccttataaa gataggttga aaacttccca gcatcaatat
    43201 ttctaaagaa ttcattgata ataaaatagt ctgcaaagga ctcttggtcc agataatcag
    43261 tgtattgctt taaatcataa gaatatagga gcttttcgat atgactgata tccttttcaa
    43321 taaactgctt ttgcttaggc gtcagacggt gcaggcttgg gtatttaatg tctaaagagg
    43381 acagacctgc ttgattcgta taggatacgt aatgatcaag agcctgctta gccttgtgtc
    43441 ttctatccca aacaaggata taaggcgttt tatcagattt tctatcactt ttttcgatgt
    43501 ttaccctatg ccgcccctgc tcaatactct ccacagccaa atacagacca caatactgat
    43561 gatccaccac taactcgcaa tacctgacgt taggtgcata ggtcatgatc tcaccggcaa
    43621 tattgtagct aagataattt cggactaggg tccgatctaa aaaaggacca tgcagcaccc
    43681 actcagactc cttggacatg ccagccagcg agactgcctt tggcttagct cttttattga
    43741 taaaccttag ctttaaggat ttcttgtcaa aatgacgtga cgaattgccc ctataagcaa
    43801 tcaatgctgt caaggacaag cgcggagact cagacaggct gtgctctcta tctagctgat
    43861 cacgaagcga gaccgtcgtt ttaatggttt tttgccgctt tgtctctccc tcgtattccc
    43921 tttgctctgg aatctgctga tgatgagtgt caatgctaat aatcggcaaa tgagagctaa
    43981 actccccagt gcttctggag ctctttttga ccgtctgcaa atggtgatga atacgctttg
    44041 cagaggtctt aggaaaaccg ataccacaaa tagcagctag caagagacac accagcacaa
    44101 tcacataaat cgtcttttct ttcatttacg tcaaccagtt atgtcatcgc tttgactaac
    44161 aatattaaaa taatcaactc gccccagctg ataaacagcc tcagttaacg gattagcctg
    44221 ctgataggtg ctgtcataat cctttcttga cagctcaaag atcatctcaa tatcatcaga
    44281 cgtggtgttt ttcacgctct ggatcgcctt acccgaaaag tagttaaaca ctaaccgctc
    44341 cagctcaatt tccatttgct tatcacagcg aacaatcaac aacagtctat tgtcatttct
    44401 gacagctccc ataagcaaca aaagcataaa gatcacgctg ctaccagttg cagcgacagt
    44461 ataatcacca acaccacagc aaatcccaac cacaatcgtc caaaaaatat agactgtatc
    44521 tctagagtct ttgattgctg tccgaaaacg cacaaccgac agcgcaccga ccataccaag
    44581 agacaaagca acattatttc cgataactgt catgacggtt gctgttaaga ccgtcaaggt
    44641 catcaacgaa acattaaact tcttgctata ggcagtccca gtgtgggtat aggcatatga
    44701 catataaatc acaatactta acaaggctgc agcaacaata tgcagcaaaa catcttgaaa
    44761 gctcaaggtc ccacgctgtt caaagacatg tcttaataat tgtttcatct taatatctct
    44821 cctaaaaacg ataatgcttg ctgatagctc tccccatgca atacttgctt gcacttagct
    44881 cgctaccatt aacagactcc aaaagctttt tgatataaga caacaaaaag ccattatact
    44941 tgacctccaa gatgaccaaa tagggatcta gcaggtaatt ctgaggcaga tgatctgaaa
    45001 aaatatcagc attggtctca gacccgataa tatgatgatc aaaggtaatg cgaatattgt
    45061 tttcctttgc cacaaatgcc ttgcgctggt attcgatcac tgtttttggc tgatagagct
    45121 gcattgacat gcgactatag cattcagcag caaagcgatc aggataagtc agcaatatag
    45181 acttgtctcc cttaatcaac aattgagcgt ctgctctggt caacctcaga gatcgctttt
    45241 tttgattgct cccttgcttt tgcttcatct ccaacttagc aaatgagctc tgactaccgt
    45301 aattgcgcag gcgaattttt cgcctaagct caataccgtc ctctttttcc tgccagtcaa
    45361 cgtcctccaa agaatcaaaa tacaaggatc gaatcacata tccctcacta gagctatgag
    45421 catctagacg caagagcttg gaaaattcat gcgataagcg ataataatcc tcaatggtaa
    45481 tcaaatactt tttttcttga cgcaatacct cattcacgcc agtgtcctcc tttttcgtct
    45541 gtaagcaatg ccttaacacc aagctgcctg taacagcagc caacaaacct gtctcataaa
    45601 taagtcaggg caaataaggt gattgttggc tctacaagag tcaatcacct gccaaaatag
    45661 taaatcctgc catctgttga aataatataa accagctgat cgtcttgatt gcaagacagg
    45721 cgcttttgtg actgatctag ctgtctgctg ctaatatcag ttgcattagc ctccttgagc
    45781 atggcctgct tgagctgttg ctggattttt ctggcttgca gctcagaaat ctcaaagctg
    45841 ccattaacct tttgagcctt gtgcttgtag accagtgcca catggtcttt agctgttgtc
    45901 ctagcagtcg acaggagccc ttctttgttg agctgagtat gctctcctac atcaatggca
    45961 acatagtcat agggtgcccg tatccggtgc gctgttagta ttgaggacaa aatccctgtc
    46021 acaaggcaga tgcttatcgt agccactatc atctgctgcc gctgcttacg aatgaacctt
    46081 gaaaaagcac agacctccgc ctgatattcc tgaagctctt cttcaacctt actgtaatcc
    46141 tgtctaagat cagccaagtc agtctgacag tccttgcagc ttgtcagatg agcctcaaca
    46201 accgctctac tataatcact caacgtatca tctacatata atggcaacaa atcctggatc
    46261 aactcacaat catacttcat agccatactc ctctcgtaat tgtcttttaa tatgttttct
    46321 tgccctaaag acaagaacct tggcagagga tactgtgatg ccaatatcct tagctatttt
    46381 ttcataggaa tctcccgaat aaatcctcgc cagaaagaca gcctgcattt tctctggaag
    46441 attaaaaata atcgttagtg taatctctaa cagctccctt cttgctatct tatcaagtgg
    46501 ttcatcatgc cctttagcat caacgatttc taagctttcc atcgacatat tctcatattt
    46561 tttcttttta atttctgtaa agaaggtgtt ctttgcaatg gtaaataacc atgttttgat
    46621 tgaactatcc ccactaaatt tagcaatatt acgataagcc tttagaaaag tctcttgagt
    46681 aatatcatct gataaactat tttgataaca gcacagctta tttacaaacc tataaacatc
    46741 atctttatat tctaaatata tgtcctcaaa ttccaacagc ttgtctcctc tcaatacacc
    46801 cttaaccatt agaccgtcca atctgccaaa agttacagat taatttaatt tttagtataa
    46861 gctgtcatca agtcagataa atagtaatga tctatcatct tattattgac tcaaacgaca
    46921 aattatattg cattttagta taagctgtca tcaagtcagg taaataacaa ggacatatca
    46981 tctaacattt gatccagaca aaaaagacct gattctgtaa tatacagaac caagtctttc
    47041 tcaatagaca ttgactagat gattgattta tagcgacata gctagatagg ctatgactta
    47101 ccgtcttttg gatttggaga caagcccgcc aagacctgcc aagataccac tgccagcaag
    47161 agccaataaa gcatctagct gactagtgcc tgttttaggg agagtcttag ctgagaactg
    47221 agaaacctct ccagcagtct gagcagcaac taatttctcc tgatgatggg ctgcttgatc
    47281 agtcattgca cctaaagtcc ccttatcaga ctgggacgcc ctaagacgga taatggtagc
    47341 tgttaagcct gatagcttga ccccgtcctt ggttagcaca accccctcag gacttgccag
    47401 cgcctcggtg cctgcttgct tggcatcgac gataacctca ccagcaagaa gagcctgaaa
    47461 ctcaccagtt agcctaatgg tacggtcatt gctatcagca ttgacaaaga cagcataaac
    47521 atcaccattg cttgctgttg tctgataagc aatcaccaaa tcctgtgcct tgatcccatg
    47581 ctcatttgga acagtgatca gcttgacctt ctggtctatc tcagccttac ttgccaagcg
    47641 aaaggcatct gtcgaacggc gcagcgcaat caatccctta gtaaaggcct gacttgtcgt
    47701 gctttcaggg tagcgctctg tatccgttgc ctttgcccag tcaaaatgat taatggcatc
    47761 tgtcgaatca taggaatcat gaataaagta tgggtattca aatggtgttc cgtcctcatt
    47821 gaccaagagg tgtgatttat ttggcacctt gtcatcagcg accttgccct tataggcttc
    47881 gtccttaaat tgctttgtac gaccatattc ctgaccagca tgtaggaaag gggtgccttg
    47941 agaggttagc accaagaggt tccctaggcg caagcgacga tgaatctctg ccgcatttgc
    48001 tgcaacagac ggatcctttt taatagactg ggcgataata tcaaacaagg tcaggttatc
    48061 atgtgcagcg atatactgaa tcacatcacc cggatcatca gccaaaaagt tagtcggctg
    48121 agccttgata ttatgaaaaa tggtcatgat atccctagca ccgcccgtaa taaaggctgg
    48181 agagccttca tttggaaagc ctgatttgag ctgattgcga aaatcatctg agaaggaggc
    48241 aacggtatct gtctgtgaca tccagctttg gtccgcaggc tgctcaggca tgtgctcatc
    48301 accctgatag gtgacccagc cctcaccaag catgatgata ttcggattaa gtgccttagc
    48361 tgctaaaaag gctttttcaa tagctgctgc atcatggtcc cccatcatgt caaaacgaaa
    48421 accatcaacc ttatactcat ccaccagata agtaatcgaa tccaccaaaa cacgacgact
    48481 catgtaatgc gttgtcccaa gtcgtccacc accaaatgag gtcctagcag tgccatcagc
    48541 attcataaag tgataataat tcggctccag gtcctcaaaa atatcaacat tagctgtatg
    48601 attgtagacc acatcaagga taacccccat accacgctta tggatttcat taacaagctg
    48661 cttaaattcc tcaatgcgct tagctgggtc ggttggatca gtcgaataca taccagtcaa
    48721 ggcaaaatag ctttgtggat catagcccca gttgtaatta ttatcacttg agctgtaggt
    48781 cagcatacgc tccttgttgg ccaattcgtt gacaaaataa tagctcatca caggcagcag
    48841 ttgaacatgc gtaataccaa gctccttgag ataatccaac ttttcaacaa aggcagcaaa
    48901 agtcccaaat tgagccttta gatcattagc aatcgcctga tctgaggtaa aatcacgaac
    48961 atgtgcctca tagataatgg cgtcctcacg cttatgaaag cccttaatat cagcaaaggc
    49021 cagctcctta tccccaatag cagcaggatc aacaatggcc gccttagcca ccttatagga
    49081 cgggtctgtc ttagcaagct cgctgttcca tgccgctaac gatttggcat aagggtccag
    49141 cacaaggaca gacttgccat ttctagtaat ctcataatga tagaaatagc ctctataatc
    49201 tgaaatccca agtccgctat ctgctgatag agtgattgac cactctccct tatcaccctt
    49261 tgctagagcg agattaccaa tcaccttggt ctgatcagcc ttatcataca aaacaagtga
    49321 caccttatca gcacttggtg accaaatcgt cagatcaacc ttagcacctg cttctctcac
    49381 acgcgctcct agctcaccgt cataagcata caggctatcc ttgtattgcc aatttggcct
    49441 agcctggaag ctctcatgat gaaaggtcac cgtataagtg gccactgctt gactaaaatc
    49501 acctgtgatg acagccttat gagtcttttc atctaaggtg atatcagtaa tagcaactgc
    49561 ttccttactg tcagtgctga tttttaattc ttttaaaagg ctttccttat ccacatctgc
    49621 tagagtcgta aagctcgcct caatactgct tgggctgacc tgctgagcac cgattaatct
    49681 aactgtatta acaaaataag ggttcgtata aatggttgga tcctcgtctt tcaagaaaat
    49741 ttgggtgtga ttctttaaat ctttaaaaat ataatcattg ggctgaattt taacagcgtc
    49801 acctgtctga cgctcatcta gcaagagaaa gcctagctca ttggtatcag ctagcttgac
    49861 atctatataa gcaccatatc gaccgacctg cttaaaatca ataccatctg gccaagcgcc
    49921 ctgctgacta gtcattgacg catcagcact tccccaaagc cagagcgatt tgttgtcata
    49981 atggccatca ctgcgataat aattgatacg gatatagccc tgagccagcg gccgatagta
    50041 agacagctcc tggccatcaa tccagacctc attcatctta gggctgagaa ggtctatggt
    50101 tcgatcgccc gtcagattgt ctcccttagt gttattgatc aaaaagctaa ccttattggc
    50161 ttgattggct gaaagcttaa cgtccatgta atagccatag tcatctgtct tcgctagact
    50221 aaaattggta gccccagtcg gccagcctcc cagctgatca gatggtgtct caacatcgtc
    50281 ccacacccaa agaccaagcg aggataggtc ttgagctggc agggtcttga aatgcagccg
    50341 caaggtctgc tccgctatcg gctcctctga gcttgtagct tctggtgtct ctagagagct
    50401 gtctgtcgta acagacacta tcgatgatga aggctgagac tggtctgtag tttcctcatg
    50461 cgcctgatcc tctacaagag gtacagctac tggctgaact tccttgacag tatcagcatt
    50521 gacagcagct gacaccttag tcacatcaga aataccagca atatcactaa tgtcagtagc
    50581 ttctggtagc tcatttgagc cttggtcagc agcctctgac ttgaccatga ccgcaccatc
    50641 agcaggctca acactcgtca gactctcagc tgctgctgtg atctgcccac tagctgtccc
    50701 caaagaaaaa gcggttgcaa tagctaccga agccactcca agcttaagct tacgaatgcc
    50761 aaataattga cgctcttcaa acagcgcttg attttccctt aaccttttca tcattcctcc
    50821 gtccttatcc tgatagttat taacacctta agtatacaaa agaaatcaca atagtgcaat
    50881 cgttttcttt attgaaaaca atgatattta tgaacaaatt agacaagaat caacgcaagc
    50941 gatttcctta ctgataaata cctgctcccc tcactaagac cagcccactg caaagcagaa
    51001 aagtagccta aagagcctta gtaacagata aatgagctta atgttgcttc atcaactagc
    51061 tggctgcaac cgttttgctc tgatgtggta acgtcttgtc atcatgacta agcttgacaa
    51121 aaaacgctgt tagttacata atcaacggtg cttggtagcc ttccattact cctttgattg
    51181 ttatacccta atgatacaca aaacctcagt ttttatagta gaatattaca ctttgttttg
    51241 acaaagatgt ttaatcttgc taaaataaac ttatcaatga gggagtacca atgatgacat
    51301 tcgaattcac atcgttattc gatttacaaa ctgcttttcc aacagagcag gcttgcataa
    51361 atcatttaga aaatatcact tggggtgacg tggtgatcag cccttttgac gctacctcaa
    51421 aggtctataa atgcaaggga aataaatacc gttgcaagaa tacagggaag tatttcactg
    51481 tcaaaacagg tactcttttt gataatacta agattaagct acaaaaatgg tttatggcaa
    51541 tctggcttgt gacttctcac aagagaggaa tctcctcagt gcaattatca aaagagattg
    51601 cagtgacaca aaaaacagca tggttcatgt tacagcgtat tcgtaaatgc tttggctctg
    51661 aaaactgaga tccacttggt gacgtcgttg aagtagataa aactgatatt gatggtaaaa
    51721 ataagaacca ccatgatcct aagaaggcaa aaacgttcaa gaaccatcct tctctgaaag
    51781 ataagtcggc agttattgga atggtgcaac aaaaaagtaa ggccaacgct catacaatac
    51841 tcgtgattac tctgatagtc ggcgttttat cttttatcag ctaatgctga tatgcgaaca
    51901 acttataagg agctgatcaa tggttaaaca tgcaaaaact aacctacact ttgaattaga
    51961 aagatctatc tctcgcaaag ttgatagtaa attgatagcc tatcaagtca gtctttcaga
    52021 tggcttttat gacaaataca ccaaattatg ggataaaacc tattcatttg attttgtcat
    52081 caaccatcgt gcgttttatg ctcagttgac caaaagatgt gtttacgatg tccttttgca
    52141 aactttggaa aaaatcagta gaaaagccat tgcaaagcaa ctagcagagc ttgaagcctt
    52201 ggttgatgtt tcggaaagta aggaagactt tcagatattt ttcgagaaaa aatacaaact
    52261 atcatttcct gatttgaaga attgtgttta tccaaagaaa aaggaacttt ccgattttga
    52321 tcaaaacctc tggatagctc tacattataa ccctagaaag gagagggata cataatgaca
    52381 acatggtatg attacatggt aagagccagc gaacactctg gaagtgatgg agacctctgg
    52441 tttcgttacc tttacaaggt tatcaaagac aaagaaacca aactaactac tgatgatgtg
    52501 gagcagttat taaaaaatcc gaatctaact ccttttcaga aggtaactct gcaagatgct
    52561 ttaacagaag gtacgcatac aagagagcat gttttacagg caaaccgtaa aagtcagcca
    52621 aaggatattt tgaaactctt tagagaggga aactatggat aaaaaaatct tattcaaagc
    52681 tctgaataca gaactagcta aagaaaatat tagccttgac attatctgtg tcggtggttt
    52741 tgtccttgaa tattacaatc tgcgaggaac acaagatatc gatgcctttt atcaagaagg
    52801 tgttaacatc aggcagatga tcaaaaaggt gggagatgag tttggcgtta atgaacctga
    52861 tgagctttgg cttaataatt cagttgccaa tcttaataga ataccaccta aaacgatttg
    52921 tgagacagta tttcactatt ctaacctaat tgtccttgtc ccacccttgt cttatattct
    52981 tggaatgaag ctagaaagcg gacgagatag ggatagacaa gatgccggag acattattaa
    53041 gctagctaat atccgttccc ctaaaaaact tatcaataca cttgaagagt atgattttca
    53101 acctgatatt tcaatgattt tagaagtctt tgaaatagct tatggcatgg aatggttagc
    53161 aaactatatg accgaacacc cagaagaatt taggcattat taaaagacga tttctgtttg
    53221 gaagtcgcct tttttgatgt ttttgaaaac accttgagat tagtctaaac taatctccat
    53281 aagcaaaaaa cagcttagcc ccgtctggga gtaagctgtt tttgctgtaa tgtatgagat
    53341 aattaggcta acatcaatca ttacataaag ggaataaagg gttaatgttt cttgcgtttg
    53401 cgtgatacta cagctacgcc tagacttgcc aatacggcaa gggctgctgc tgtaaagaat
    53461 ggagctgttg cttctcctgt tgacggaagc ttgtgttcca ttgctttagg taccgctggt
    53521 ttatctcctt tctgtgcttc
//
LOCUS       DARYJX010000010        52142 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYJX010000010 DARYJX010000000
VERSION     DARYJX010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52142
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..727
                     /locus_tag="TU257_000572"
     CDS             <1..727
                     /locus_tag="TU257_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0833610.1"
                     /translation="NKYKETKMGGRKRILLPEEEWEIIHNTHEAIVSREVFDKVRIIK
                     KKRIFGGYAKNREESVFSDKIFCKECGRHMGFRCDSRQKKNPNKVYKYRNYYCYFCKA
                     SRTPNNVKERDIIELIRPKLDEFKLQNTEKDKKTMDYEKIKEEYLREISALNSNLQII
                     YENYKKNSISKEEYLRKKILVQDRKKLLENKIKELENVEDDSKKELDINNLDEDNLLK
                     IYVDNIIDKIIASRTGEIEIIEK"
     gene            768..1382
                     /locus_tag="TU257_000573"
                     /pseudo
     CDS             768..1382
                     /locus_tag="TU257_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1912..2790
                     /gene="mvk"
                     /locus_tag="TU257_000574"
     CDS             1912..2790
                     /gene="mvk"
                     /locus_tag="TU257_000574"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL0833611.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2772..3716
                     /gene="mvaD"
                     /locus_tag="TU257_000575"
     CDS             2772..3716
                     /gene="mvaD"
                     /locus_tag="TU257_000575"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL0833612.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3709..4707
                     /locus_tag="TU257_000576"
     CDS             3709..4707
                     /locus_tag="TU257_000576"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL0833613.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4710..5702
                     /locus_tag="TU257_000577"
     CDS             4710..5702
                     /locus_tag="TU257_000577"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL0833614.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5987..7270)
                     /locus_tag="TU257_000578"
     CDS             complement(5987..7270)
                     /locus_tag="TU257_000578"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL0833615.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(7257..8432)
                     /locus_tag="TU257_000579"
     CDS             complement(7257..8432)
                     /locus_tag="TU257_000579"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL0833616.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            8617..9456
                     /locus_tag="TU257_000580"
     CDS             8617..9456
                     /locus_tag="TU257_000580"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL0833617.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            9537..10034
                     /locus_tag="TU257_000581"
     CDS             9537..10034
                     /locus_tag="TU257_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL0833618.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            10054..10224
                     /locus_tag="TU257_000582"
     CDS             10054..10224
                     /locus_tag="TU257_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833619.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            10260..11489
                     /gene="clpX"
                     /locus_tag="TU257_000583"
     CDS             10260..11489
                     /gene="clpX"
                     /locus_tag="TU257_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL0833620.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            11499..12098
                     /locus_tag="TU257_000584"
     CDS             11499..12098
                     /locus_tag="TU257_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL0833621.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            12462..15464
                     /locus_tag="TU257_000585"
     CDS             12462..15464
                     /locus_tag="TU257_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL0833622.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(15654..17747)
                     /locus_tag="TU257_000586"
     CDS             complement(15654..17747)
                     /locus_tag="TU257_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0833623.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            18118..18537
                     /gene="ndk"
                     /locus_tag="TU257_000587"
     CDS             18118..18537
                     /gene="ndk"
                     /locus_tag="TU257_000587"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL0833624.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            19038..19844
                     /locus_tag="TU257_000588"
     CDS             19038..19844
                     /locus_tag="TU257_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0833625.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(20136..21101)
                     /locus_tag="TU257_000589"
     CDS             complement(20136..21101)
                     /locus_tag="TU257_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0833626.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            21273..22556
                     /locus_tag="TU257_000590"
     CDS             21273..22556
                     /locus_tag="TU257_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL0833627.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            22558..23418
                     /locus_tag="TU257_000591"
     CDS             22558..23418
                     /locus_tag="TU257_000591"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL0833628.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            23583..24842
                     /locus_tag="TU257_000592"
     CDS             23583..24842
                     /locus_tag="TU257_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL0833629.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24842..25465
                     /gene="folE"
                     /locus_tag="TU257_000593"
     CDS             24842..25465
                     /gene="folE"
                     /locus_tag="TU257_000593"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL0833630.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            25473..26273
                     /gene="folP"
                     /locus_tag="TU257_000594"
     CDS             25473..26273
                     /gene="folP"
                     /locus_tag="TU257_000594"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL0833631.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            26280..26639
                     /gene="folB"
                     /locus_tag="TU257_000595"
     CDS             26280..26639
                     /gene="folB"
                     /locus_tag="TU257_000595"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL0833632.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            26636..27142
                     /gene="folK"
                     /locus_tag="TU257_000596"
     CDS             26636..27142
                     /gene="folK"
                     /locus_tag="TU257_000596"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL0833633.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            27238..28125
                     /gene="murB"
                     /locus_tag="TU257_000597"
     CDS             27238..28125
                     /gene="murB"
                     /locus_tag="TU257_000597"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL0833634.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            28171..29325
                     /locus_tag="TU257_000598"
     CDS             28171..29325
                     /locus_tag="TU257_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833635.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            29309..30103
                     /locus_tag="TU257_000599"
     CDS             29309..30103
                     /locus_tag="TU257_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833636.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            30100..30876
                     /locus_tag="TU257_000600"
     CDS             30100..30876
                     /locus_tag="TU257_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833637.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30869..31942
                     /locus_tag="TU257_000601"
     CDS             30869..31942
                     /locus_tag="TU257_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0833638.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            32100..33632
                     /locus_tag="TU257_000602"
     CDS             32100..33632
                     /locus_tag="TU257_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL0833639.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33838..34452
                     /locus_tag="TU257_000603"
     CDS             33838..34452
                     /locus_tag="TU257_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL0833640.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34800..35927
                     /locus_tag="TU257_000604"
     CDS             34800..35927
                     /locus_tag="TU257_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0833641.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            36079..36756
                     /gene="radC"
                     /locus_tag="TU257_000605"
     CDS             36079..36756
                     /gene="radC"
                     /locus_tag="TU257_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL0833642.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36758..37453)
                     /locus_tag="TU257_000606"
     CDS             complement(36758..37453)
                     /locus_tag="TU257_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL0833643.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(37465..38109)
                     /locus_tag="TU257_000607"
     CDS             complement(37465..38109)
                     /locus_tag="TU257_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL0833644.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(38395..38742)
                     /locus_tag="TU257_000608"
     CDS             complement(38395..38742)
                     /locus_tag="TU257_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL0833645.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38732..39859)
                     /locus_tag="TU257_000609"
     CDS             complement(38732..39859)
                     /locus_tag="TU257_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0833646.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39862..40836)
                     /locus_tag="TU257_000610"
     CDS             complement(39862..40836)
                     /locus_tag="TU257_000610"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0833647.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40971..41543)
                     /locus_tag="TU257_000611"
     CDS             complement(40971..41543)
                     /locus_tag="TU257_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL0833648.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            41638..42309
                     /locus_tag="TU257_000612"
     CDS             41638..42309
                     /locus_tag="TU257_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL0833649.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            42284..43120
                     /locus_tag="TU257_000613"
     CDS             42284..43120
                     /locus_tag="TU257_000613"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL0833650.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            43117..44019
                     /locus_tag="TU257_000614"
     CDS             43117..44019
                     /locus_tag="TU257_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0833651.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            44023..45024
                     /gene="pta"
                     /locus_tag="TU257_000615"
     CDS             44023..45024
                     /gene="pta"
                     /locus_tag="TU257_000615"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL0833652.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            45124..45882
                     /locus_tag="TU257_000616"
     CDS             45124..45882
                     /locus_tag="TU257_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0833653.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45987..46673)
                     /locus_tag="TU257_000617"
     CDS             complement(45987..46673)
                     /locus_tag="TU257_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL0833654.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46928..47656
                     /locus_tag="TU257_000618"
                     /pseudo
     CDS             46928..47656
                     /locus_tag="TU257_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            47649..49181
                     /locus_tag="TU257_000619"
                     /pseudo
     CDS             47649..49181
                     /locus_tag="TU257_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            49539..50522
                     /gene="guaC"
                     /locus_tag="TU257_000620"
     CDS             49539..50522
                     /gene="guaC"
                     /locus_tag="TU257_000620"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL0833655.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50708..51289
                     /locus_tag="TU257_000621"
     CDS             50708..51289
                     /locus_tag="TU257_000621"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL0833656.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(51577..>52142)
                     /locus_tag="TU257_000622"
     CDS             complement(51577..>52142)
                     /locus_tag="TU257_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0833657.1"
                     /translation="DQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAALI
                     NLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQIK
                     DKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPEV
                     EGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14847 a         9809 c        11928 g        15558 t
ORIGIN      
        1 taataaatac aaagaaacca aaatgggagg aagaaaaaga atcttgcttc ctgaagaaga
       61 atgggaaata attcataata ctcatgaagc gattgtttct agagaagttt ttgataaggt
      121 aaggataata aagaaaaaaa gaattttcgg gggatacgca aaaaacagag aagaatctgt
      181 tttttctgac aagatttttt gtaaagaatg cggtagacat atgggattta gatgtgatag
      241 taggcaaaag aaaaatccaa ataaagtgta taaatataga aattactatt gttatttctg
      301 taaagctagt agaactccca acaatgtcaa agaaagagac attatagagt tgataagacc
      361 aaaattagat gaatttaagt tacaaaatac agaaaaagat aaaaaaacga tggattatga
      421 aaagataaag gaagagtatt taagagaaat atctgcatta aatagtaact tgcaaataat
      481 ctatgagaat tacaagaaaa atagtatttc aaaagaagaa tatttacgaa aaaaaattct
      541 tgttcaagac agaaagaagt tactggaaaa caagataaaa gaattagaaa atgtagaaga
      601 tgattccaag aaagaactgg atattaataa cttagatgaa gataatttgt tgaaaatata
      661 tgtagataat ataattgata aaataattgc atcaagaact ggagaaatag agattataga
      721 gaaatagata attcaggaaa ttctatatca attgcttgac attgtaggga aagtcctcta
      781 tcatgaattt gctgtatcgc ttttatgatg tacaatcagg cctcattaca gttgatgggc
      841 aaaatattca ggagtattct agagaaagcc tgcgttcaca gatgggtatt gtcttgcagg
      901 atccttattt gtttacagga acgattgctt ctaatatcac gatgggaaat ccagcttatt
      961 cggatcagga tattttagat gctttggaaa aggtcggagc ctcttcgatg attgctcgtc
     1021 tggaaaaggg cattcatgag cctgtctatg aaaaaggctc ctcttattca agtggcgagc
     1081 ggcagctaat tgcttttgct aggacattga ttgccgaccc taaaattttg atcttagatg
     1141 aagcgacctc gcacattgat actgagacag aggacatcat tcaacaggct atggaggtct
     1201 taaagaaagg ccgaacaacc tttatcattg cccatcgctt gtctaccatt caatctgcta
     1261 atcaaatttt agtattggat aaggggagga tcgtcgaaag aggaacacat caggaattgc
     1321 tagatcagca aggcatttat gctgaaatgt ccaagctaca agaaaaggtg gctgtacagt
     1381 aatgcttttt agtgatagct atcaaaaaat tccttttcta ggccgtgtta agcagcagta
     1441 gtctgtgaag taggagctat atttaggttt tgtgcctaag cctttaaggt ttttaagagg
     1501 ctggattagg gcttaacatc aataaaatca tatgtcactt tatcacagca tgttgtggtg
     1561 aagtgttttt tgtgtcgtcc tgctaaaggg aagatcctca cagtcagggc ttggctggct
     1621 cctttatcag agtcagatca ttcatacgta cttcctgtca ggcttggcta agttgaattg
     1681 tatgttgaga tcagcatgtc agcaatttat gctttgtgtc tgacttttag cagcttgtac
     1741 atgaaatagg actaaaggac acttgaattg atgaagaatc agcttaaaaa ccatttgtcc
     1801 tagataggat aagaactgtc taaaaggggg atagatcatc gcaattttta acaatttagt
     1861 gtaaaatagt aaggtgaatg ttttgatgaa ataaacgaaa agatttagga tatgaataag
     1921 acaattggat atggcaaggc acacagcaaa atcattttaa tgggtgagca ttctgtggtc
     1981 tatggctacc ctgcgttggc cttgccctta aaagatattg aagtgacctg ccggattttc
     2041 cctgctgcaa agcccttagc ctttgatttt tatgatccct tatcaacggc agtttatgca
     2101 gccttggagc atttggggtg cttggcagag cccattcatt atgatattat gtctcaggta
     2161 ccacaaaagc ggggcatggg ctcctcagca gctgtttcga ttgcagctgt tcgagctgtt
     2221 ttttcttatt ttgggcagcc cttgtcagat gagctgttgg aaatcttggt gaataaggca
     2281 gaaatcattg ctcacaccaa tcccagtggc ctagatgcta agacctgcct cagtgataag
     2341 gccatcaaat ttattagaaa tgttggtttt gataccattg atattcagtt aaatgcttat
     2401 ttggtcattg ctgatacagg gattcagggg catacgcgtg aggctgtcaa taaggtggct
     2461 caatttgagg aggaaaatct tcctcattta gccaagcttg gctgtttcac agaggctgtt
     2521 gagcaagcaa ttaagacaaa cgattgccta gctattggac gattcatgac gcaggcacat
     2581 gaatcactaa aggctattgg tgtcagtgtg gcaaaggctg atcagctggt tgcagcagct
     2641 cttgaggctg gcgctttagg agctaaaatg actggtggtg gcttaggagg atgtatgatt
     2701 gcattagctg aaaggataac agacgctcag caaatcagta agaaactaaa agaagaggga
     2761 gctgtaaata cgtggattca aatactgtaa cggtaacttc ctacgctaat attgctattg
     2821 tcaaatactg ggggaaaaaa gatgaggcta agatgatccc atcaacctct agtatttctt
     2881 tgaccttgga aggcatgtac acgacaacaa gtctttcttt tttgcctgcc tcagcaaagg
     2941 gagatcagtt ttatatcaat ggtgttctgc aggacgccaa ggagcatgct aagattactg
     3001 cgattttgga tcagttccgt cagaaggacc agacttttgt caaggttgaa gccagcaaca
     3061 gcatgccaac tgcggcaggc ttatcctcaa gctctagtgg cttatctgct ctggtaaagg
     3121 cctgcaatca gctttttcaa gctaagctaa gtcaagaaga gcttgcccaa aaggctaagt
     3181 ttgcctctgg ctctgcttcg cgttcttttt ttggccctgt tgctgcctgg gataaggata
     3241 caggctctat ttataaggtc aaaacagatt taaagctggc catgattatg ctggtcttga
     3301 acgatgctag aaagcccatt tcgagtcgag aggggatgaa gcgctgcagc acaacctcaa
     3361 caagctttga ccagtggctg gcccagtcag aaagtgatta tcaggccatg ttgcgtgccc
     3421 ttagtgacaa tgattttgaa acggttggtt ggctgacaga agcaaatgct ctagccatgc
     3481 acgcaacgac caaaacagcc agtccttcct tctcttacct aacagaggcc tcctatcagg
     3541 ccatgctaag ggtcaaagag cttcgtcaag agggctattc ttgctatttt acgatggacg
     3601 ctggtccaaa tgtcaaggtg ctttgtttag aagaggactt agagcggctg tcgcaccttt
     3661 ttgaaaggga gtatcgtatc atcgcctcaa aaacaaagga attaccagat gtctaaatat
     3721 catgttcaag caggaggaaa gctgtatctg acaggcgaat atgcgattct aaggccgggg
     3781 caaacggcgt tgatttgcta tattcccata atgctgacag ctgtcattga agcagcagag
     3841 gctgttagta tcagctcaga tatgtttgac catgctgctg atttgtcacc ggataaggat
     3901 tataggctga ttcaagcctc tattgaagcc tttagtttat atatagataa ggatattaag
     3961 gagctgccag ccttttcttt gtctattact ggtaagcttg agcgtgacgg taaaaagttt
     4021 gggattggct ctagcggtag tgttgttgta ctaacgctaa gagctttggc agccttttat
     4081 caggttcagc tgctaccaga gcagctcttt aagctggctg cttataccct gcttaaatca
     4141 ggagataatg gctccatggg ggacattgcc tgcattgcct atgagagctt ggttgcttat
     4201 acatcctttg ataggcgtaa ggttggtcaa tggttgatcg agatgaccct aaaagagcta
     4261 atggcagcac attgggggta tacgattgag actattgagc ctgctctgcc ctgttggttt
     4321 cttgttggct ggacccaagt cccttctatc tcaagagaga tgattcagct ggttaacaag
     4381 agcattagct gtcagttttt agagcaaagc cagctggtca cacaggaagt gatgactgcc
     4441 ctgcagcttg gtcaaagaaa aaggctcaaa gctagcattg aaaaagcggg tcagttgctg
     4501 caagggttgg cttcagttat ttatcaccct aagcttacgc agcttgtcca ggcttgtcaa
     4561 gggcttgatg ctgctgccaa atcatcaggc tcaggaggtg gggattgtgg tattgcactc
     4621 gtttttgagg ctaaggacat tgagcctatc cttgccagat ggcagcaagc agggattgta
     4681 ttactatatc aggaggaatg gggataaaca tgactaatcg taaggatgac catatcacac
     4741 atgctttgag ctatcattct ccttacaatg catttgacga catggagctc attcactgtt
     4801 ccttgccgag ctatgattta gctgatattg atctctcaac ccattttgct ggctgtgatt
     4861 ttgagtttcc tttttatatc aatgcgatga caggtggtag caagaaaggc caagcagtca
     4921 atgaaaagct ggccaaagtg gctgcggcta caggtatttt aatggtgaca ggctcttaca
     4981 gtgcagcctt gaaaaatcct gaggacactt cctttcaatt gcgaggtgta gcaccagatt
     5041 tacagttggc caccaacatt ggtcttgata aggctgttga cctagggatt agagctgtcg
     5101 aggaaatgaa gcccttgttt ttacaggtac atgtgaatgc catgcaggag ctgttaatgc
     5161 cagagggaga gcgcagcttt aagcattgga aggatcattt agcggcctat gccaagcagc
     5221 ttccagtccc tttgatttta aaagaggttg gctttggtat ggatattaag accatcacta
     5281 tagcacgtga tatgggagta aaaacctttg atatttcagg aagaggagga acctcctttg
     5341 cctacatcga aaatcaaaga ggaagtaatc gctcttacct agacgattgg ggacagacaa
     5401 cagtgcaatg tctattaaac gccaaaggtc tggttgatga agtggagatc ttagcctcag
     5461 gtggtgtcag acacccctta gatatggtta aatgcttggt gctgggggca cgtgctgtgg
     5521 gcctatcgcg agtggtattg gagttagttg agacctatcc agttgagcag atcatcgcta
     5581 cgatcaatag ctggaagaag gagcttaagc tcatcatgtg tgctttagat tgtcgaacct
     5641 tgagcgattt gcgtcaggtg gattatttat tatatggtag gctttatcag gcaaaccgct
     5701 aaagactttt tagccctgag ctaactttcc ttagaaaatc atcacaggag ttaagaagct
     5761 gcctgcttgg tgctgcaagc taattcagct gattatggct cgtaagattt ttagatgtct
     5821 gaatgaaatg ataggacaga tgacatagta tagcgctaat ttctagtgaa aatcagtcct
     5881 tggtcaggtt actgagactg aggttaagtt tatgtttaca ctaacactta aaggatatga
     5941 aaacacttgg tagctgccac tgaagctgtt accaagtgtt tttagtctat gattggctta
     6001 atcgtatggc tgttaagagc tgtcctgcct tttctaggtt cattggctta tcctttagta
     6061 gagccttaac tagttgaggc acctcctgct cactagcacc tgctaataga gctagagact
     6121 tggcctgcag cttcatgtga ccagcctgga taccagttga ggtcaaagcc tttagagccg
     6181 caaaattttg cgccagccca actgcagtgg tgatttgggc gagaacctta gcatttggtt
     6241 gctctaaaag gctatgagca acactgacgg ttgggttgag accgatcgac cctcctttac
     6301 tagcaatggg cattggcagt gttagctctc cgcataagct atttttagat aaatcaacgt
     6361 gccagctact tagccctcta taagagccag tccttgcggc ataggcatgt gctccagcct
     6421 caatagctct ccagtcattt ccggtagcta tagctaccgc atcgattcca ttaaagattc
     6481 ccttattatg cgttgctgct cggtaagggt caatctgggc taatttgctt gccagctcta
     6541 tttttttggc caattgctga gcttcttcct tatgtcgact taggtatctg aggtcaacct
     6601 gacatttagc actaactaaa gcttttgttg catagtttga gaggatagcc attaagcatt
     6661 gaccaccgct tagggcctcc aaatcaggta ctaaagcctc catcatcgtg ttaacgatgt
     6721 tggctcccat agcctcttgg gtatcaacgc tcagatagac aatgaaaaaa tcctccttac
     6781 gctcaacggt aaggctcttt gcgccaccac cacgcttaac aatagaaggg taggcattgt
     6841 ttgcaacgtc aatcaatgta tctgcgttag ctagaatagc cagcctagcc tgctcgtcat
     6901 ctttaacatc ataaagagct acctgcccaa gcatttgacg actgagtacc tcagtctgaa
     6961 agccacctga tcgcttgatg attttggcag caaaggaagc agcagcaaca acagaaggct
     7021 cttcagtcac aaaggggacc tgataggtat gcccattgat cagaaaatca ggggctagac
     7081 taaaaggcag agccagtcga ccgatgacat tttcggtcat ttgattggca atagcaatgg
     7141 gtaagagctg gtctgtctct aacagctttt gctgctgcgg gccaagcagc tggtcatctg
     7201 cgagctgttg aatgcgttct gcaaggcttt ttttataaaa gccggcccaa tttggtttag
     7261 tttttgtcat catcttgata aattcgttgg tgttccttaa tttctttgag ggcaaacctg
     7321 ccagttagat atggtgaaaa gctggcattg ccatcttggt ctagtctagg ctcttcataa
     7381 aaaagtgctt cataatcagc cactgaaatc acctgacgtt ggtctaatag ggcttgtcga
     7441 ttagtcagta gcatgtcctt gtaaccgtca acaagctgcc ctgaaaacag ctcactaaca
     7501 gctcctgagc catagctaaa caatccaatc ctatcaccag cccttagcac ctgactattc
     7561 tctaaaagtg ataataagcc gaggtagagt gagcctgtgt aaatgttgcc gatttgcttg
     7621 ctgtaggcaa tagaagcttg aaagttttca taaagccttt ctttgtgatc atctgctagt
     7681 gattttgtca tgatcttatg aagtcccttt agagcaagct ttggaaaggg gatatgaaaa
     7741 caaacagcag caaggtctga tagctcaata ccttcttttt cttggtattt gtcccaggtt
     7801 gtttttaggg aatcaaggta ttgcttggtc gaataaatac cattgacaaa tggtgttgag
     7861 ctgtaatttg gacgccaaaa atccatcaca tcacgtgtct gtgcgacatt gtcatgattt
     7921 aactggagaa tacgaggatt agtagtaact agcatagcaa tacttccagc accttgtgtt
     7981 ggctctccgg cggatccaat gccgtatttg gcgatgtcac tggcaatgac caagaccttg
     8041 gaggctgggt gtgcagcaac atgtaatttg gcataatcta aagcagcagt agcgctgtag
     8101 caggcttcct ttatctcaaa ggagcgtgca aagggctgaa tatcaagcag ctgatgaacg
     8161 taaatactgg ctgcctttga ttgatcaatg cttgattcgg ttgctaaaat gaccatgtca
     8221 atgcttgctt tatcgtcttt ggtaaggatt tggtcagcag ctgatgcagc aagcgttaca
     8281 atatcctctg taacaggtgc aatgcttaga gcgtcaagca ttagcccctg atgaaatttt
     8341 gctggatcag tgctgcgagc aagtgccagg tcttccattt ttaagacgta ttgactggtc
     8401 gcaaagccaa tcttatcaat tccgatgttc ataaatatcc ttcttttatc cattttatag
     8461 tcctatccat tttatcatat tttcttagaa aattagctga tttaatacga tagttttacc
     8521 tttcaaacca aaaacagcag catatagctt tcttctggta tttttgaagg aaattagata
     8581 aaataatatg gactgtgctt acagaaaggg gtttccatga caaaagcaga tcatattttt
     8641 aaagctaata tcaaaaaaat tatggaggag ggagtcttta gcgagcaggc tcgcccaagg
     8701 tacaaaaatg gtcaaacagc caattccaaa tacattacag gtgcttttgc agagtatgat
     8761 ttgtctaagg gagagtttcc tattacaact ctaagatcaa tccctatcaa gtcagctatt
     8821 aaagagttat tttggattta tcaggaccaa tcaaacagcc ttgatgtttt agaaaacaaa
     8881 tacaacgttc actattggaa tgagtgggag gtcggtcaga caagaaccat cggtcagcgc
     8941 tacggtgcaa tcgttaaaaa gcatgatatc atctcaaaaa tcctcaagca gctagaggac
     9001 aacccttgga atcgccgaaa tgtgatttct ctgtgggatt acgaagcctt tgaagaatca
     9061 gaaggactgc taccatgtgc ctttcaggtg atgtttgatg ttaggcgagt agatggtgag
     9121 ctgtatttag atgccacgct gacccagcgc tcaaatgata tgctagtggc tcatcatatc
     9181 aatgccatgc aatatgttgc cctgcagcta atgattgcca agcattttgg ctggaaggct
     9241 ggtaagttct tttattttgt caataatttg cacatctatg acaaccaatt tgcgcaagcc
     9301 aaggagctat tggagcgtca gccagcagcc tgtcagccca agcttttgct gcatgttcct
     9361 gatgggacag acttttttga tataagacca gaggattttg agctacagga ttattaccca
     9421 gtgaagcctc agctcacctt tgacttggcg atttaagcga aaaagacgat tttttctgag
     9481 cattttgcca agaaatttga tagaataaaa gaagttcata ttgaggaaag ctagtgatga
     9541 caaagaagat tattgctatt tgggcagagg atgaagcagg acttatcgga gcgtgtggca
     9601 ggcttccttg gtacctacca aaagagttgc agcatttcaa ggaaacaaca ttgaatcaag
     9661 ctatcctgat gggacgagta acctttgagg gcatgaaggg tcgtttgctg ccaaatcgcc
     9721 aaacgcttgt tatgaccaga gacagttatt atcatgtgga gggcgcttta accataacca
     9781 gtgtgcagga ggctttggat tggtatcatg cgcaggataa gaccttatat gtgattggtg
     9841 gcagcaaggt tttagaggcc tttgatggtt attttgatgt catcatcaaa acagtggtac
     9901 atcaccagtt tgagggtgat acctaccgac ctaggttaga gctgagtgat tttgtagagg
     9961 agacctctgt attgtaccca agggacgata acaatcctta cgatttcact gttacagtat
    10021 tgagacatcg ctaatatagg gagatgatag tctatgcagc gtagtatttt tggggtattt
    10081 acggcctttt tgtgtgcgat ttgtgtttta tgtgccatac cggcctttag aaaaaatcgc
    10141 tatggcttag gattactttt tttattaaat gcctttacta acctagtgaa taccatacat
    10201 gccttttatg gaacactgtt ttaagcctaa gagaatgaaa agagaaagat agaggaatca
    10261 tggcaggaaa tcgtagtaac gatattaagg ttcattgctc gttttgcggc aagagccaag
    10321 acgaagtgaa aaaaattatt gcaggtaata acgtctttat ttgtaacgaa tgtgttgcct
    10381 tatcacaaga aatcatcaag gaagaattgg cagaagaggt tctcgctgat ctgactgagg
    10441 taccaaagcc aaaagagctg cttgagattt taaatcaata cgtcattggg caggagcgtg
    10501 ctaagagagc cttatcagtt gcagtttaca accactacaa gaggatttca tttactgaga
    10561 gtcgtgatga tgatgatgtg gatttgcaga agtccaatat tctgatgatt ggaccaacag
    10621 gctcaggaaa gacctttttg gcacagaccc tggctaagag tctgaatgtt ccgtttgcta
    10681 ttgctgatgc aacctctttg actgaggcag gctatgtcgg agaagatgtg gaaaatatcc
    10741 tcctgaaatt aattcaagcc gctgattaca atgttgagcg tgcagagcgc ggcattattt
    10801 atgttgacga aattgataaa atcgctaaaa aaggtgagaa tgtctctatc actcgtgacg
    10861 tatcaggaga aggtgtccaa caagccttgc taaaaatcat tgaaggaacg gttgctagtg
    10921 ttccaccgca aggtggtcgt aagcacccaa accaagagat ggtacagatt gataccaaaa
    10981 atatcttgtt tatcgtcgga ggcgcctttg atggtatcga agaaattgtc aagcagcgct
    11041 tgggagaaaa gatcattggc tttgggcaaa atagtcgaaa gattgatgac aatgcttcct
    11101 atatgcagga gatcattgct gaggatattc aaaaatttgg tctgattccc gaatttattg
    11161 gacgcttgcc tgttgtggca gcgcttgagc agcttaatac tgaggatttg attcgtattt
    11221 taacagagcc tagaaatgcc cttgtgaagc aatatcaagc cttattgtca tatgatggcg
    11281 tagagcttga gtttgaaaag ggggctctgg aggctattgc aggtagggct attgagcgca
    11341 agactggtgc gcgtggtctg aggtctatta ttgaagaaac catgctggat atcatgtttg
    11401 aggtgccaag ccaagaggaa gtaatcaagg tacgcattac taaggaagct gtcgaaggtc
    11461 aatcaaagcc tattttagag atagcctaag gaggtatgat gtctgaagag caaatcctta
    11521 acacgcataa tgcttcgata ttgcttagtg cggcaaataa gtctcattac ccacaagacg
    11581 accttcctga gattgctttg gcaggtcggt caaatgttgg aaaatcaagc tttatcaata
    11641 ctatactagg acgtaaaagc cttgctagaa cctcaagcaa acctggtaaa actcagcttc
    11701 ttaatttttt taacgttgat gataagctaa ggcttgttga cgttcctggc tatggttatg
    11761 ctaaggtatc taaggcagag cgggctagat ggggaaagat gatcgaagag tacctgacca
    11821 cacgacaaaa tctcagagca gttgttagtc tggttgattt tcgccatgag tcatcacagg
    11881 acgacattca gatgtatgag tttttgaagt attatgagat tccggtgatt attgtggcta
    11941 caaaggcaga caaggttcct cgtggtcgct ggaataagca tgagtctatg gttaaaaagt
    12001 ccttaaactt tgatcaaaca gatgcgttta ttattttttc atctgttgag cgtatcggta
    12061 ttgatgagtc ttgggatacc attttagagt atttataagc atatggtaaa aaatttaagt
    12121 atcttttaga caggcacttg tgtctggtct gagaggtgct tttttattga caaaaaaaca
    12181 atttgttgat gacgagcttg tgttcaaaaa tgtcagtttg ctaaaaaatg atgataacaa
    12241 acaagacttt tatgatataa tgcttagcag gataatatgg agacatgaga aaaaggtcag
    12301 agacagctaa tttgctatcc ctgattataa ctatgatgac cagcattatt ataatactca
    12361 tggtgctagc tattagtagc agcacctaac ctatagtgtt gctttttagg ttacaagcac
    12421 tggcgctagg agtattataa tatatttaga aaggtttttt tatgacaata aaaaaatgcc
    12481 ctcaaatact tgccttattc cttgcttttg cagcgctagc tagtcagggg caaaccgtcc
    12541 atgctctgga gcggcaggag acatctgtca agcaagctca tgaatcagat gattggtttg
    12601 atgaggacga aggagttagc gatatcaagt ctaatacccc tacagagata gactcaacag
    12661 taacagagtt atttggtgat gctgagccta agactaaggc tgaaaaagaa gagtcaaaag
    12721 ctccaagccc taagcaagaa gcactgccag cagagtctca aaaagaaaaa gagacatctg
    12781 ctaaatcgac tgaccatgcg acagtacaag cagaagaggc acagcctgag caaggctcag
    12841 atagtccttg gctagcagat gactttgtta ctaagggaga taccttggtt gggctatcta
    12901 aggcaggtct tgctaagtta tcaaagacac ctgtcttggt actaccaagg atagggattg
    12961 acaagacagt gttgacaagg attgctagct ttgcctttac tccaaataaa tcagtcgcta
    13021 ttgctgatta tacaggtaga gcaggtgaac atggcgagat caatcatctg gacgtcgaag
    13081 gcagagatat ccttactgag ggagaggatt ttggtgccta tgcgattaaa aagcttgtga
    13141 ttcctgaagg ctatcttttt atcggtcaag atgcctttaa tgacaataaa cagctagaag
    13201 aaatcagtct acctgatagc ttactcagta tttcagacta tgcctttgct cacatgagtt
    13261 tatctaagct taagctgcca aaaagcctac agtccattgg agatcaagcc ttttttgata
    13321 atcggattgc aggcactttg gtattgccaa aagctctaaa gcagctggga gaacgcgtct
    13381 ttaagtccaa tcgcctcact ggacttgtct ttgagggaga aggcttgtct gtcctaaaag
    13441 aagcagcctt tcaagacaat gctttcatta gtcttgttat cccagatagc attcaagcct
    13501 tagaagagga cgtctttaca ggaaaccttg gcgatgaaga atacggtaat catgccgttt
    13561 tacgaaccaa aaatggtcag aatccttaca gacttcacag tgccaatgtt cttgtcaatc
    13621 caagtgatca ggctagaaca ccacagccac caattgatta caacaggtgg cttgcagaag
    13681 attttaccta tactggacag acgataaccg gtttttcagc tagtggactg cgcaaggtca
    13741 aacgcaataa gcatttggtt ctgcctaaga attatcaggg tcagcccttg acagccattg
    13801 cagataatgc ctttagaaat gtcaattttc atgataaaac cttgcgtaaa tacgacctag
    13861 aaagcgtgac gttaccatct accattcaaa agattggtgc ctttgccttt cagtcaaata
    13921 atctagaaag ctttgaggcc agcgaggact tggttgagat tggtcaagga gcctttatga
    13981 ataatcgcat tgagattctg gccttgaatg ataagctgaa ggtcattgga gatgcggcct
    14041 ttcatatcaa tcggatttat gctattgtta tccctgagtc ggtcgaagta attggcattt
    14101 ctgcctttag gcaaaatggt gctaaacatg tgatgtttat gggagataag ctaataagta
    14161 ttggagaaat ggcttttttg agcaatactc tggaggaagt ggatttgagc agcttagcag
    14221 ggcttaagac catcgctgtt caagcctttg cagacaatca cttgagagag cttaagctgc
    14281 cagatagttt gatgcgtatt gaagcagaag cttttaaaat taatagactt caaagagtga
    14341 ccgttccaga cactgtcatt agcattagct ttaatgcctt tgatcataat agtgatgaca
    14401 aggttgtcct aaggaccacc aatcacaata aaaacctgct agctgatgga aatggcttta
    14461 ttgtggatcc agacctatta agtgcggatc aatcgactgt tcaagcagtt ttagaggacc
    14521 tgcggcgctt agatctagct agtctacgtg ctgatacagc agctcatttt atgacactca
    14581 tcacaagagg taagcagcta ctaaaagaat ccgctgtacg gttaggttat cagcttaggt
    14641 tccttgcaga gtcacgattt ttcttagggc gcgtgagact ggatcagctg attaaaactg
    14701 ctgacataac cctatctagc catcaagaca cacctaatgc taagctgttg atggctaagc
    14761 tagacaaggc caagctgcat tacaataata gcgcaatgac tgctccaaaa gtaagtcgct
    14821 tggaaaaaga gctcagcctg ttaattgatc ttgtccaagg ggtaggcgct atctctaaag
    14881 caacaatgac tcaaggtgtc tataagcttc agacaaccct acctattcca gagtattata
    14941 ttggggttaa tctttatact gatgatcagg ggaatatttt atttgtgctt gacatgagtg
    15001 atacgattgg gcagggacaa cttgatgact atggcaatcc tattttaaat gttgatgagg
    15061 ataatgaagg ctaccatgct ttggccattg agtccttagc agattacgaa ggccttacga
    15121 ttaaggatat attgaccaag gagctaaatc aattgcctat tcgcgatgtc aagcaagcaa
    15181 gagagcatcg tgttggtctt tttatggcaa tcagagatgc tgcaagggaa gctcagcttc
    15241 tactagaaaa gcagagcaaa gccttatcag aatcagccgg caaatctaat ggctcaaaag
    15301 tagctgactc aggacttgag ccttctgtga cactatcaac caataagact aagctgctac
    15361 caaaaacagg agccttcaaa gaagcttggg tgacaatgat cggaatgctt gttcttttgg
    15421 cggctaccct acttaaaggc gatagtcgct acaaaaagaa gtaaataggc ttgcttagca
    15481 agcacactct agcaccagta aggcttgagg ggcttacaaa gcctatctaa tctagcaata
    15541 gtatattgcc agtgtgagct ggtgcttgag cttcaaaaaa acaaaagagc ctgaaatgac
    15601 ttttactagc atttcaggct ctttttagct tgtgattctt ttttgtgtga agcttacttc
    15661 tcacttatcg taatagtatc ttgatcaagg cttgctaata ggtgtttagc agtcgggtga
    15721 tccaggtagt aatccgtaat gcggtcacga atttcttgtt cgatgacacg tctaagtgga
    15781 cgaactccca tcgcatgatc atagcccaga tcaatcaaac gctctttaac atcgtcagtc
    15841 acctcaaggc taatgccttt tttagcaagg gtttggttca cttctgttag cattaaagca
    15901 acaatttctt gtaaatcctt tttcgctaaa tggttgaatt cgatgacacc gttgaagcga
    15961 ttcaagaatt ctggtctaaa gtaaggtgca atacgctcca tgatagcagg ctcttgatca
    16021 gcacgatctc ctgcttgatg gccaaaacca gcattagagg ttgcgatgat aaccgtattt
    16081 ttgaaattga tcgtgttgcc ttgtccatct gtcaatcgcc catcatcaag cacttgaaga
    16141 agcagtgtaa tgacctgtgg gtctgctttt tcgatttcat caagcaagat gatagagtaa
    16201 ggactgcgac ggacacgttc tgtaagggta ttttgattat catcatagcc aacatagcca
    16261 gctgttgttc cgattaattt ggaaacagct gtgcggtcac tatattcaga catatctaag
    16321 cgaatgatag cgtcctttga gccgaacata tcaagggcta actgcttagc cagctcggtc
    16381 ttaccaacac cagttggacc aacaaagagg aaggagccaa ttgggcgatt accgtcatca
    16441 aagcctgcgc ggttgcgtcg aatcgcacga gcaacagcct caactgcacc atcttgtccg
    16501 ataacatggc ctttaagacg gttactgatt tccttgagcc tttctaaatc actagccccc
    16561 atatttgata ctggaacacc agttagacgt tcaacagatt ctgcaatatc attaacagtg
    16621 gcagtgacct tttgcccttc actgtgatga ttgatttgct tttggagctc ctcaatgcgg
    16681 gtcttagcag ttaaggcctt ttcaaagtct tcttctgcaa cagccttttc ctgtagctcc
    16741 ttttgcttag tgatttctgc ttcaagtgat tttagatcag tgacagggtg ctgagctgct
    16801 agatgagcag cagtcatatc aacaaggtca atggctttat ctggtaggct tcgttgtgga
    16861 atatattgga tagcataatc aatagctgcc ttcaagacag agtctggtag gatcacattg
    16921 tggtgctgct cgtagaggtt gcgaatgccc attaaaatgt ggaaggtatc ctctgctgaa
    16981 ggagcattaa ccttaacctc gttgaaacga cgagcaagag cagcattttt tagaatggtg
    17041 ttgcgatact catcttgagt tgtggcacca atcagggtca actcaccgcg tgagagggct
    17101 ggttttagaa tatcagctaa gcccttagag cctgagtctg aaccagctga ccctgcacca
    17161 aggatttgat ggatttcgtc aaagaagaga atgatattgc cagcctcctt aacctcttta
    17221 accatgtttt gaatgttttc ttcaaaggag ccacgatact gtgtgccagc ctcaaggcca
    17281 gaaatatcaa ttgagataat ctctttattt ttgatggcag ctggcacatc accgttgaca
    17341 atagcctggg ctaggccttc gacaacagca gttttaccaa caccagcgtc accgacaaga
    17401 acagggttat tcttggttcg tcttgctaga atttctgcgg tcgcttgaat ctcatcgttt
    17461 cgtccgatca caggatctaa cctgccttgc cgagcttctt cggtcaggtt tgttccgagc
    17521 ttggttagaa tgccgtcttt tttaaggctg ctagcctgtt tttcttgtcc ctcagctgca
    17581 gctagcttac cggttttccg gtattcttga aattcctctg gtgtcatctc acgtccattg
    17641 acaagatagc gacgattttc gctgcggtag ccgccgatgt ttcccattaa ctgattgaaa
    17701 atatcgtcca tattttcaaa ggggtctttt ccataatagg ttgccatata cacttacctc
    17761 acttgtatta tatttaccag tcattatgag ctactggtat aggtagaagg tgatcggtgt
    17821 tggctcatac agagatcata gagaggtctt atgagagtct attgctcagg cttattactc
    17881 accttctaat aatattatat ccaaaaggtc agtaaaggtc aaacaaaaag tatgaataat
    17941 taacctttat aatcaggtgc ttatagccct tgaaacatca gatgactatg ccataagctg
    18001 ctggtgcttt tttgctagca aggctatctg taaagaagag acttttgtca aaaatggttt
    18061 tactttttgt tctaaaggct ttcatgatat aataaaagaa aagcacagag gtcaattatg
    18121 gaacaaacat tttttatggt gaagcctgat ggtgtgaaac gtggcttggt tggagagatt
    18181 ctacgccgga ttgagcgtcg tggctttacc tttgataggc ttgaattgcg acaagcaacc
    18241 ccagaattgc tagctaagca ttatgacacc ttaatcaata agccctttta tccagagcta
    18301 gaggcctata tgacaagcgg acctgtttta atcggcatta tctccggtaa tcgtgtggtc
    18361 tcttcctggc gaaccatgat gggggtaacc aatcctaaag acgctttacc ggggactatt
    18421 cgtggtgatt ttgctcaagc ccctggtgat gatggcggca ttttcaacgt ggtgcatggt
    18481 tcggattcga gagattcagc caagcgagaa attgcgatct ggtttggaca tagctgacat
    18541 tgggcttggg cctattcttt taagaactga taaagcaatt gcataagggg ttgataagcc
    18601 catcatcaat agtagctcag cattagaagg gtaacagcct tgatgttggg ctattttttt
    18661 gcttgcctag ggtctgtatg cttgtcctga tgagcaggta gacaaagcag cataagttta
    18721 acaatccttt gcggcagtga tcaattgtag ctctaaccat agcatcagct atttgaaagc
    18781 cttgaaaaag aaagctaagg ctaacaagct agtctaggtc atttactaca agcgactttt
    18841 ttcaattagc tgctcaaggc aagtattgaa aaaagtccat ttttcatgtc atttgtaata
    18901 atatggtata tttttaacga aaagtcgttt tagttgagaa aatatacaaa aaaggctatg
    18961 atatagttaa taaagttgtt ataccccctg tgtcttgtac actatgactt gtagagagtt
    19021 tatcaaagga ggataagatg aacaaacaaa gcatgaccca tttttctaag aagctgatga
    19081 agttagccct tttaggtttg gcattgccat taagcttggt gtcggtggta gatactccgg
    19141 ttcttaacca atccgaaaaa gctgtttatg ccaatgattt tggatctgga aatcgagcca
    19201 gtgattatgt accggcggct aacgcttgga gctttgaggc ttatccagat tactacagta
    19261 ttttaggagc tagtcatctt aatcctgctg tctttccaga gcctagtaag atgtcataca
    19321 gtcctttaga cgagttgggc cgcacacagg tcgcaagagg aacaataacc tatcacaata
    19381 tcgtgatgaa ttacaatgtt cggcaacgct ttgctaaaaa tcagaaccct tcaggctgga
    19441 ttggtaaccc tagaaatgtt cgctacacta ttgagtggct agatggacta tcctatcagg
    19501 gagatttttg gaatcggagt catttgattg cagatagcct tggtggagca gccttacgtg
    19561 tcaatgctat tactggtaca agaacacaaa atgttggcgg cagaaatcaa agaggcggta
    19621 tgcgctatat tgagcaaaag gtgcagcagt ggattgagca gcatacaagc gcagttgttt
    19681 attacgaagc ggtgccaatt taccaggcaa atgagctagt tccaagagct gttgttgttt
    19741 cagcattgtc atcagacgga ggtcttgacg aaaaggtcat ggtctataat accgccaacg
    19801 gctataccat tgattatgcc actggcgcat tccgcagtaa ctaggctttt gtactaagct
    19861 gtagctgatc aaggtctgac taagacaagc tcatcagcaa ttggtatata aaaagacgtg
    19921 gcaacaacat gttttaaatg agttgtcatg tctttttagt gtcgtcagct tttcacattg
    19981 tcttagaatg atcacaccta gctagccgct aaaagcattg gtccaaagaa atgttaagaa
    20041 tagatagaat gccttttaat cagtggtatg ggactgctag ctaatataat gcctgcagtt
    20101 gagccaattt ctcatctagg ctaataacta acaagctatt gacttatcgt gttcattaga
    20161 atgtcagctg ttgtagttgg tagtattcga atacgattaa gcgatagcag gccattagca
    20221 gcacttgcta gtccttcatt tgttgtgacc cctaatttgt aatgcagatc ctcagcaatc
    20281 tttaatgtgg tatcagtata acgacctgct ggataggcaa ttgcaatggt atcttggtgt
    20341 agctctctat ctaggtattc tttagaatct ttcatttcag cggtttgact agcagcgctt
    20401 gcctgagata gatcagggtg gttaaccgta tgatcttgga aagacatgcc tgcctgcttc
    20461 atttccttca tctgatccaa tgtaagattg gccgcattac ctgcctctgt aaagccagtg
    20521 ataacgttat tggtggcctt gatgtcatac tttttcagga ttggaaaagc aacgttgtaa
    20581 aaatcaacca tgctatcatc aaaggttagc cagacaacct tttcagcagg aagctcgtta
    20641 gctgataaga ctcggtaggc ttcttcggga gataaaaagt agtagccggc ctccttcatt
    20701 gcctttagct ggctttcaaa aagatctgga gcaacgatga gattggcact tgctgcctct
    20761 tctggtgcca taacgtgaat agcatgatac attaagatag gaagcttaac agggttttgc
    20821 tgcttggtcc agctgacagc tcctttttgc tgctgactat ttgtatggct agcttcctta
    20881 ttagttgctt ttttgctagg cttgggagct ggttttttat cagtttttga aaataggctt
    20941 attttgggga ttgcctgcga taattgagag atgcttatct ttgaatggct cttgtaaagg
    21001 tagacaatag ctgataagcc tatgatacag gcaagtagta gcatgagatt aatcattttg
    21061 aagatttttc ttttcttacg ccgtttgttt ctgttgttca tcacttgctc cttgtttatt
    21121 gattagtcta ttgtaacatt tttttaagta agctgtcttt cgttaactta attttttgct
    21181 aacattctat tagtgttatg ctttgtaaaa caagacctag atttgctata ataagacaga
    21241 gtatttaaga cagtcaaaaa aaggaggata ggatgtcagt taaggttgca ttattaggct
    21301 ttgggactgt tgctagtggc attcccttgc tattagaaaa caatagtagc aagattcgtg
    21361 cagtggtagg tgatgatttg gtgattgcaa aggttctggt tagagatgag accactaaga
    21421 agcgtttgtt ggatcaaggc tattcctacc aatttgtgac ctccattgat gatattgttg
    21481 atgatgagag cattgatatg gtggtcgaat taatgggtcg tatcgagcct gcaaagacct
    21541 ttatctcgcg tgctctatca gccggaaagc ctgttgtgac tgctaataag gatttgatag
    21601 ccttgtacgg aggagagctc tcgactttgg cagctaagca tcaggtagct ttgtactacg
    21661 aggctgctgt tgctggtggt attccaatac taagagcttt ggctgattcc tttgcctcag
    21721 ataagctgac gcgtctgctc ggtgtgctca atggaacaac taatttcatg ttaaccaaga
    21781 tgattgatga gggctggacc tatgaaaggg ccctgcaaaa agcgcaggag ctgggctatg
    21841 ctgaaagtga tccgactaat gatgtgaaag ggatcgatgc agcttacaag gttgctattc
    21901 ttagtcagtt tgcttttgga atgaccattg actttgaggc tattagctat tcagggattg
    21961 ataaggttcg agtagaagat gtgacagtag cgcagaagct gggctatgtg atcaaattag
    22021 ttggtctact tgaagagacg gcttctgggc ttaacgcaga ggtatcccca gtctttttac
    22081 caaagacaca cccgttggct gctgtagacg gtgtgatgaa tgctgtttat atcgagtcaa
    22141 ttggggttgg gcaggctatg ttttatggtc caggtgccgg tcaaatgcca acagctacag
    22201 ctgttgtggc agatatgatt cagactgcct gcaccttacg tgaccataca gtctcagtct
    22261 ttaatcgttt tgctacaaaa actagactag ctaagtctga ggatattatg agtccctatt
    22321 actttgctat tcaagcaact aataagtttg gtcagctact agagctaaca aggctatgtg
    22381 atgtttgtgg cattagagtt gagcagctgt tatcagatga gatagatagt gacaggttag
    22441 actttgtgat gattactcat gagatgagca aaaaggagct tgcttgcttt acagcgctac
    22501 tacaggatca tcaggatttc cgtatgttaa gtacatttaa gattttagga gattgacatg
    22561 aagatacgcg tacctgcaac ctcggctaat ttgggacctg gatttgactc aatggggatt
    22621 gctgtttcaa aatacctaga agttgacatt ttagaagaac gtgaccaatg gtttattgag
    22681 catgatttgg gtgatattcc aaatgatgat agcaacttac ttatccaaac agcccttagg
    22741 ctagcaccaa atattccagc acatcgtcta aagatgacgt ctgatattcc attggcacgt
    22801 ggcttgggat cgtcctcctc ggtgattgtc gctggtattg aattagctaa tcagctaggg
    22861 catttaaacc taacagacga ccgtaaattg gccatagcaa ctcgtattga ggggcaccct
    22921 gataatgtag ctccagcgat ttttggtcaa ttggtaattg cttcacagat tggtaaggac
    22981 gtggattaca tcattgcgcc ttttcctgac ctttctttgg tttgttttat tcctgattat
    23041 gagctgaaaa cctctgattc cagagatgta ttgcccaagc agctatcgta taagcaggca
    23101 gtggctgctt cctcagttgc taatcttgct atagctgcgc tattgaccgg taatttgaaa
    23161 aaggccggtc gggcgattga aaatgaccaa ttccacgaaa tctaccggca aagattagtc
    23221 agagagttcc agccgattaa gcgagctgca gcagctaatg gtgcttatgc aacctactta
    23281 tccggtgcag ggcctgctat tatggttatg tgtcccaata agaaaaaaat ggcgatttat
    23341 gaggccatcg agcagctagg tctaattggt cagttggtgt ctctagagct ggatcgtcag
    23401 gggctgtgtc ttgtctagac tggcaaggta ctggtatgct tgcctagtag gcttattgtt
    23461 gatatcagat ggacttaaag cttagtcatt caaatacatc aaaaaagtga ggcttgatcg
    23521 ttttatcggc tttcactttt ttcttgatat gttatactag agtagacttt gtgaggtgtg
    23581 tgatgaatta tcaagaaaca ttagactgga ttcatggtca ggaaagattt gggatcaagc
    23641 caggtgtaaa acgcatgcgt tgggtgcttg agcagctagg taatcctcaa gataggatta
    23701 gaggaatcca tgtggtcggc acaaatggta agggatcgac ggtcaatgac ctacagcata
    23761 tttttactag agcaggctat gaggttggaa cctttacctc gccttatatc atggatttta
    23821 aggaacgtat ctgtctcaat ggtgagatga tctcagagac tgaccttgtt aaggctgcta
    23881 attgtattcg tccactaacg gatcgcctta tcagtgagac aagtttgggt cctgcaacag
    23941 tctttgagct gatcactctg atcatgtttc tttattttgg tgagagtcac ccggttgata
    24001 ttgctattat cgaggcagga ttaggggggc tttatgactc cactaatgtg tttcaggcga
    24061 tggctgtggt ttgcccgtct attggtcttg atcatcaagc tattttaggt gatacctatg
    24121 ctgacattgc ctatcaaaaa gccggtgtgc taaagggtgg tgaagacctt atttttgcca
    24181 ttgataacaa agaggccaga caggtttttc taaaaaaagc agagcagctt ggcgtgccta
    24241 tttgggaatg gcgtcgacag ttcaacatgc tacagggtga aggtggttat caatttaaca
    24301 gtcagcttgg tcagctgtct catctagtgc ttgcaatgcc tggtcagcat caggtagcca
    24361 atgcaggcct agccactatg acaagcttga tattacagga tcggtaccca aaggtaactg
    24421 agtctgttat tagagaggct ctggcaagca gcttttggtt gggacgaaca gaattgttgg
    24481 cacccaacct gatgattgat ggtgctcata ataatgaaag cattgccgcc ctgattgatg
    24541 tgatatcatc agactatcag gataagcaga ttcatattct atttggtgcc attgatacca
    24601 agcctgtctc agatatgctg cagagtctgg agcgtcttgg agatgtgcaa gtaacaagct
    24661 ttcactatcc caatgcctat cctttggagg cttatccaga taggctaaca aaagtagcag
    24721 attttagagc atttttagac cggcttgagc aagcagctgc tgatgatttt ttcctgatta
    24781 caggctctct ttacttcatc tcagaggtca ggcagtattg gaaaaaggta ttaagcaagt
    24841 aatgctttct cacatcaact catcaaacaa gattaatcaa ctaaaaaggg gaaaaccatt
    24901 gccaatcaat caaaaaaaag cagaagccgc tatctatcaa ttattagaag ctatcggtga
    24961 ggatccaaac cgagaagggc tacgagatac cccaaagcgt gttgccaaga tgtatctaga
    25021 aatgctctca gggctggaac aggacgctaa ggatgaattt acagctgttt ttacagagca
    25081 tcacgacgat ttggtgattg ttaaggatat tagcttttat tccatgtgtg agcaccatct
    25141 ggtgccattt tatggtaagg cgcatattgc ttatttgcct agtgatgggc gtgtgacagg
    25201 cttgagtaag ctggcaaggg cagttgaggt gacgagcaaa agacctcagc tgcaggagcg
    25261 tttgacagct cagattgcta atgctcttgt tgatgccttg cagcccaaag gggtttttgt
    25321 tatggtagaa gcagagcata tgtgcatgac catgcgaggt gtcaaaaagc caggcagtaa
    25381 gaccattacg acaactgcta gagggattta caaggatagt agagacgaca ggcgtgaggt
    25441 tatgcaatta atcatggagg gctagggtat ttatgactat tggacattat tcagccgctg
    25501 gtgaggcagc tattatgggg attttaaatg tgactccgga ttcgttttca gatggtggct
    25561 cctatactag tgttaatcag gccttggcac aggccgaaaa aatgctgtca gaaggagcga
    25621 ctgtcattga tattggaggc gagtcaacac gaccgggctg ccaatttgtg ccggcagaag
    25681 aagagattgc acgcgttgtt ccaatcataa aggccattaa aaaacggtat gatgtcctta
    25741 ttagcattga tacctacaag acagaaactg ctagagcggc ccttgaagca ggagcagata
    25801 tgctcaatga tgtctgggca ggactatatg acggtcaaat gctaagtcta gccgccgaat
    25861 acgacgttcc cattatatta atgcataatc aaaccaaaga ggcttatgct gatgttacaa
    25921 aagaggtttg cagcttttta caggctagag cagctgcagc cctcaaagca ggtgtcaaaa
    25981 aagaacatat ctggcttgat ccaggatttg gctttgctaa aaatgttgag caaaatatag
    26041 ccttattaaa agggctaaat gaggtttgcc agttgggcta tcctgttctt tttgggattt
    26101 ccagaaagcg tgttgtagac gccctacttg gtggcggcac taaagccaag gatcgtgacg
    26161 gggctactgc cgccctatca gcctacgcta ttaataaggg gtgtcaaatg gtgcgcgtgc
    26221 ataatgtcgg tgctaacagg gatattgtct ctgtattgag tcaattaagg tgagaaatga
    26281 tggataaaat cagattagag gcttgtcgct tttatggtta tcatggtgcc tttaaggagg
    26341 agcaggtctt aggtcaaatt tttgtagtgg atttagaatt atcagttgac ttgatggctg
    26401 cctctctttc agactgccta gaggatactg ttcattatgg tttagttttt gaaacagtcc
    26461 gtcaaattgt tgaggaaaag acctttacgc ttatcgaacg tttggctggt gccatttgtc
    26521 aagagctatt tgcccagttt ttgcctatta aagcgattaa aatcgctatt aaaaaagaaa
    26581 atccaccgat tgcaggccat tatcaagctg tcggtattga attggagaga aagagatgac
    26641 acttgtttat ttaggcttgg gaactaatat gggagatagg gcaggctacc tacaggcagc
    26701 agttaatgcc ctatctaagc tgccagagac tgagttactg agacaatcct ctatctatca
    26761 aacagcagcc tggggaaaaa cagatcaaaa tgcctttttg aatatggctt gccagctaga
    26821 tactaggctg acatcagaag ctcttttggc agctacgcag gctatcgagc aggctctggg
    26881 acgagttcgt catgaaaaat ggggcccaag gacaattgat attgacctct tgctgtttgg
    26941 tgatgagccg tatcaatcag agaccttggt tattcctcac ccttacatga cacaaagagc
    27001 ctttgttttg attcctttat tagagattgc acccgatgtg accttacctg gtagccagaa
    27061 aagcctgagg tcttaccttg atgctttaga gcaatcagat gtagccttgt ggtcacatga
    27121 gtattcaaat aagttttctt aaactgtcgt tatttttact aaaatttgat ataatagtgc
    27181 tactctttgc tgattttttg tcttatatta agaaatgatt gaagaaagaa gaagattatg
    27241 atagctgaac ttgaaggcat tgatattcga gagaatgaag ccttaaaaca ttacacctat
    27301 acccaagtag gcggtccagc agatttcttg gcttttccta gaaatcatta cgaactatcc
    27361 cgtattgttg attatgccaa tcataatcat attccttgga tggtccttgg aaatgccagt
    27421 aatctcattg ttcgagacgg tggtattcgt ggctttgtta tcatgtttga taagctcaac
    27481 gccgtccgcc ttaatggtta taccttggag gcagaggcag gcgctaacct cattgaaaca
    27541 acaaaagttg ccaaatttca tagcttaaca ggctttgaat ttgcttgtgg cattcctgga
    27601 agcatagggg gtgctgtttt tatgaatgca ggtgcttatg gtggagagat tgctcatatt
    27661 tttttgtcgg ccaaggtctt gacaccagaa gggaaaataa aaaagatctc agccagagag
    27721 atggcctttg gctatcgtca ctctgtcatt caagaaactg gtgatattgt gatttcagcc
    27781 aagtttgctt taaaaccggg taatcatgac agtatttgtc aggagatgaa tcgcctcaac
    27841 caccttcgaa agctcaagca gcccttagaa tttccctctt gtgggtccgt ttttaagcgt
    27901 cctcctgggc attttgcagg gcaattgatt atggacgcta acctaaaagg gcatcgtgtt
    27961 ggcggtgttg aggtctctaa aaagcatgca ggctttatga ttaatgttgc tgatggctct
    28021 gccaaggatt atgaggactt aattgctcat gtcattagga cagttgagca ggcatctggc
    28081 gttaggcttg agccggaggt tcgtattatt ggtgaaagcc tttaatgatt gtgttatcaa
    28141 aaaagaaaaa ttgtggagga tttatgacaa ttgactaagc caattatcac atttgacaat
    28201 gtctcaaaga catttgagga cagcgggaca caggtcctaa agaacattaa ttttgagctt
    28261 gaggagggaa aattttacac cctgcttggt gcctcaggat ctgggaaatc aaccatttta
    28321 aatattatgg ctgggctgct tgatgcgacc agtggtgata tttatttaga tggtgagcgt
    28381 atcaatgatt tgccgaccaa taagcgtgat attcacactg tttttcagaa ttatgctttg
    28441 tttcctcata tgacggtttt tgagaacgtt gcctttgctt taaagctgaa aaaggttgac
    28501 aaacaggaga tagcaagacg tgtcaaggaa accttaaaaa tggttcagct ggagggctac
    28561 gaaaagcgat ccattcaaaa gctttccggt ggtcagcgtc agcgtgtagc gattgctcgt
    28621 gcgattatca atcagcctcg tcttgtccta ttagatgagc cactttctgc ccttgatttg
    28681 aaattgagaa cagaaatgca gtatgagctg cgtgagctgc agcagcgact gggcattacc
    28741 tttgtttttg ttacccatga tcaggaagaa gcactagcga tgagtgattg gatttttgtc
    28801 atgaatgatg gtgaaattgt gcaatcaggc acacctgtag atatttacga tgagccgatt
    28861 aatcattttg tagctagctt tattggtgaa tcaaacatca tcaatggtac gatgattaaa
    28921 gactatctgg tttcctttaa cgggaaagaa tttgagtcag ttgatggtgg tatgcgaccc
    28981 aatgagccag ttgaggtggt tattcgaccg gaggatttac aaatcaccct gccagaggaa
    29041 ggaaagcttc aggtaaaggt agatacacag ctctttcgtg gtgttcacta tgaaatcatt
    29101 gcctatgatg atttaggcaa cgaatggatg attcactcaa cccgcaaggc cattgaagga
    29161 gaagtgattg gtttagattt cacaccagag gatattcata ttatgcgcct caatgaaaca
    29221 gaagaagaat ttgatgctcg tatcgaagaa tacgttgaaa tcgatgagca tgcggatggc
    29281 ttaatcaatg ctattgagga ggagcgcaat gaagaaaacc tctagcctct ttgcagttcc
    29341 ctatttttta tggattgtcc tctttgttat ggcaccggtt gcccttttgc tttatcaatc
    29401 cttttttgac atcgaaggac gattgacact agccaattac gagacttttt ttagctcatg
    29461 gacttacctg agaatgggct taaactctat cttatatgct ggtatcgtta ccttggtgac
    29521 ctttttgatt tcatatccca cagctttatt gttaacgcgt ttaaagcaca agcagctgtg
    29581 gttaatgctt attattttac caacctgggt caatctgctc ctcaaggctt atgcttttat
    29641 ggggattttt gggcagcagg gtggtatcaa tagcttttta acctttatgg gcttaggacc
    29701 acagcaaatt ctgtttactg atttttcgtt tatttttgtg gcctcttata ttgagctgcc
    29761 ctttatgatt ttgcctattt ttaatgcttt agatgatatt gatgataata ttatcaatgc
    29821 cagtaaggac ctgggtgcca atgactacca gaccttttca agggttatct ttcctttgtc
    29881 gctaaacggt gttagagcag gggttcagtc tgtttttatt cccagcttga gtctctttat
    29941 gcttacgcgt ctcatcggtg gaaatcgtgt gattacgctg gggacagcta ttgaacagca
    30001 tttcctaaca acagaaaact ggggcatggg ctcaaccata ggtgttgtcc taattatcgc
    30061 gatgattgtg attatgtggc taacaaagga gaaaagtaaa tgaaaaaatt tgccaatctt
    30121 tacttagcgt gtgtttttat tttgctctat attccaatct tttacttgat tgtttattct
    30181 tttaacaagg gtggagacat gaatggcttt tctggcttga cgctagagca ttataagacc
    30241 atgtttgatg atagtcgctt gatggcgatt ttattgcaga cctttgtgtt agcctttaca
    30301 agtgccttgc ttgcaaccat tatcgggacc tttggggcga tttttattca tcagagtaaa
    30361 aagaagtacc aaaatgcgat actgtctgca aataatgtgt tgatggtttc ccctgatgtg
    30421 atgataggtg cctctttctt gattctcttt acgtccttga aatttcaatt aggaatcctc
    30481 tcggttttga tgagtcatat tgctttttcc attccgattg tggtcttaat ggtgcttcct
    30541 cggttgaagg aaatgaatca agatatgatt aatgcagctt atgatctagg agcaaatcac
    30601 tttcaaatgc taaaggaggt tatgcttcct tatctgacac cgggcattat cgcaggctac
    30661 tttatggcct ttacttattc cttagatgat tttgcggtga ccttttttct aacaggaaat
    30721 ggctttacaa ccctgtctgt tgagatctat tcgcgtgctc gaaggggtat ttcattagat
    30781 atcaatgcct tatcaacgat tgtctttttg ttctcaattc tattagtcat tggctattat
    30841 tacatttcac aggacaagga ggaaaagcat gcgtaagcta tactcttttt tagcgggaat
    30901 tatcggggtt atcttgctgc ttgcgaccct gtcctttatt ttgcagaaaa aaacgagctc
    30961 tgctagtcaa tctgataagc tggtgattta taactggggt gattacattg atcccgcttt
    31021 gctgaaaaaa ttcactaagg aaaccggtat cgaggttcag tatgagacct ttgattccaa
    31081 tgaagccatg tacaccaaga tcaaacaggg tggaacgacc tatgacattg ctgttccgag
    31141 tgattacacg attgacaaga tgattaagga aaagcttctt gttaagctag ataagtccaa
    31201 gcttgttggt ctagataaca ttggtcagga gtttttagga aaaagctttg atccgcacaa
    31261 tgattattcc attccttatt tttggggaac ggtaggcatt gtctataatg accagctggt
    31321 ggataaggct cctatgcatt gggaggattt atggcggcca gaataccaaa atagtatcat
    31381 gctagttgat ggtgctcgtg agattttagg tgttggattg accacatttg gctatagcgt
    31441 taactcaaag cacctaaagc agcttgaagc agctgaaaaa aaactacagg ccttaacccc
    31501 taatgtaaaa gcaatcgtcg ctgacgagat gaaggggtat atgattcagg gtgacgctgc
    31561 tattggtgtt accttctcag gagaggctag cgaaatgctg gacaataacg accatctaca
    31621 ctatgttgta ccatcagagg gctcaaacct ttggtttgat aatctggtgc ttcccaaaac
    31681 aatgaagcat gaaaatgaag cctatgcctt tatcaacttt atcatgaagc cggaaaatgc
    31741 agcacaaaat gctgaatata tcggctatgc cactcccaat acaaaagcga aggctttatt
    31801 gccagatgat attaaaaatg acccagcctt ttacccaact gacgagaccg taaagaaatt
    31861 agaggtttat gataatttag gctctaaatg gcttggtatt tacaacgacc tttacctaca
    31921 atttaagatg tatcgaaaat aggtcatgca agattgaagg agctattcat tggaaagctt
    31981 cttcagtctt ttttagcttg gtctggtctc aataatctca tgagattaaa aagaactaga
    32041 atcttgcttt cgtctttgat acaatagtag tggtttatta aaatgaaaga gatgacaaaa
    32101 tggaaaatca taaaaacgag tttacctttt ccaaacattc aatcatagcc tacgtttggc
    32161 gtggcatttt agtcgggata attgctggag ctattgtcag tttgtttcgc ttattgattg
    32221 agatggttag tgaggctgtt gttggctatt atcaccaagc tcacagcaat cgcatgctcc
    32281 ttgttccgat agcaggcttt agcttattag ctgttttttt agttggtctt ttggtcaagt
    32341 ctgacgccaa cattaaaggc tctggtattc cacacgtcga aggggagcta aagggcttga
    32401 tgtcacccaa ttggtggagt gtgctttgga aaaaatacct tggtggaaca attgccattt
    32461 ctatgggctt aatgcttgga agagaaggcc cttctataca attaggggct atgtcagcta
    32521 aaggcttagc taagtacctg aaatctagtc gtctagaaaa acgtgtcttg atcgctagtg
    32581 gagcagctgc tggcttatca gctgctttta atgcgcctat tgcaggactg ctttttgttg
    32641 ttgaggagat ttaccaccat ttttcaagat tagtgtggat cactgccttg gttgcaagcc
    32701 ttgttgcgaa ctttatttcg ttgaatattt ttggccttag acctgttttg gccatgccta
    32761 aggccatgcc ctttcttgcc ttacatcaat attggctgct cttaatctta ggccttgtgc
    32821 ttggctgtct gggctttctt tatgaagagg tcattttaca ttttcatagg gtttatgatt
    32881 ttcttggaaa gagcttgcgc ctagcgccgc attttcatgg gctgattgtt gttgctatta
    32941 tcctgctgat tggctattat ttgccacagc tattgggcgg aggtcatggt ttgattatgt
    33001 ccttgtcaga gcaaaagcta ccactgttga ctgttcttgc ttacttcttt attcgatttt
    33061 tagggagtat gtttagctat ggcagtggcc tgcctggagg aatttttttg cctattctaa
    33121 ccttaggtgc cttgtccgga actatttttg gattgattct tcagcaaata ggactgttag
    33181 atcgccagat gattcctctc tttttagtat tgggaatggc aggctacttt gctgctgtat
    33241 caaaggcacc cttgacagga atgatcttag tgactgaaat ggtaggggat ctgaagccct
    33301 taatggccat tgctgttgtg accttcgtgg cctacttggt gatggatttg ttaaatggtc
    33361 agcctatcta tgaagcaatg ctagagaaaa tggctatcaa acacccaaca gatctagtgg
    33421 agccgaccct gatcgaatta cctgtaagtg agaaaattgc aggcagatat gtccgagacc
    33481 tgaagctacc taaaaacgtt ttaattacaa cgcagctcca ccataagaaa tcacaggtcg
    33541 tctcaggtga tacgctattg atttcaggtg ctacgatctt tttggtggtc aatgaagctg
    33601 atacaggctt tgttcgagag gtcttgatgt agagcaaggt cggttaagca gtcagcagta
    33661 gctgtgctac cgatcaaaga agcagatcag tgctttttct catctgatga aaggtattga
    33721 tttgcttttt ttgtgttatt aaacctttgt tagcaagagc catagcctta gcagtcgtat
    33781 ctgatgaata cctgctgtct ttttgttata cttaagtatc aatcaaagga gctttatatg
    33841 ctagaagtta tttcaaaaga gctgcgccat taccaaaaga ataagcttgc cgcctatcaa
    33901 aaaaagaacc aaggcataga agctggtgga attgtttttg ctggcgattc gttaatcgaa
    33961 tttttcccgt tgaaaaaata tttcaaacag gtctcaacca tttataatcg cggaattgca
    34021 gggatagaca gtcagtggtt gctagagcat attgacagtc atgtgaatga tctggagccc
    34081 agtcatgtgt ttatcctgat tggctgtaat gatattgggc ttggctttga tcaatcgcat
    34141 atcgtatcga ccattgttga tcttattagt cgtattcgca gtcagtctat ttatactagg
    34201 attagccttc tgtccttatt gccggtttct gaaaatcccg cctatcaggc gactgtcaag
    34261 ctaaggacaa atagggctat tgatgagatt aatcaagcat tagcaatgat accagcgatt
    34321 gaatttattg atcttaacgc ctgcttaaag gacgagactg gtggcttagc agctgcttat
    34381 acggtagatg gcattcatct taatgccctt ggctatgaac acttagctca agctattagt
    34441 ccctatctat gaaaggtaaa ggctggagct gctaatttgt aagggatctt taaaaaacaa
    34501 gcactgatga atcatcattg aaacccttca gagtgccgat aggctgcaca atcaaagaag
    34561 cattaggttt gtctatgacg cccttgtgtt aagctggctt ttaggtttat actgcgagaa
    34621 aatcagtcat tgggctggga gtctcaaagc ttagctgtgg taattaaatg cgagctcctg
    34681 ctagcttgtg ctgatcaagc agtatagcaa ggagggactg aacttttagt ctcagataat
    34741 attagacttt ttatcctata ttaaacgatt tagtgtataa taaacaggaa ggagttaaaa
    34801 tgaaatttga aaaaaaacaa gtcttttatg ttgtgcttgc ctttgtgctt tgttatgcta
    34861 ttcaagctaa ttgggataat ggggctaata ttgtcacaac cgtttataag acaagcctgc
    34921 cctttcttta tggagcagca gtcgcctata ttgttaatat tgtcatgagt gcctatgaaa
    34981 gagcttatac ttatacccta aaaccctttc cttttgccat gaaggctaga agagggctct
    35041 gtatgctttt ggcatatttt acctttatca gcttgatcgt atggattatt tctattgtaa
    35101 tccctgattt gattgcaagc attagctcgt taacgcaatt tgatacaaga gctatcaagg
    35161 aggtcatcag tgatttaggt cacaataagc tgattgcacg tgccattaat tacattggtg
    35221 gagatgctaa gctgacagaa acaattacca attatagcca gcagctgctc aagcaattta
    35281 taggtgttct aaccggtatt ttgacatcgg ttacagcagt tgcctcagcc attatcaatg
    35341 tggttatcag ctttgtcttt tccctgtatg tgcttgctag caaggaagag ctttgtcagc
    35401 aggcaactac cttaattgac acctatactg gtaaatacgc aaaggccatt cattatttag
    35461 tgggtttgct gcatagtcgt tttcgtggct tctttgtgag tcagacgctt gaagcaatga
    35521 ttttaggctc cttgactgcc attggcatgt ttatcctgca attacccttt gcaggaacta
    35581 ttggagtctt ggttgctttt actgccttga tccctgttgt tggtgcttca atcggtgctg
    35641 cgataggctt tgttttgatt atgactcagt caatgtcgca ggcagtcgtc tttattgtct
    35701 ttcttgttat actacagcaa atcgagggga attttattta tcccagagtg gttggtgggt
    35761 ctatcgggtt accagctatg tgggtcttaa tggcaatcac cattggtgct gctctcaaag
    35821 gcattgttgg tatgatcgtt gcagtgccat tagcggcaac gctttatcaa gtggtaaagg
    35881 atcacattca taaaaagcag gccttacaaa atcgtcagtc cagctaatta acagcatcag
    35941 atcaaggaaa acgtctatta caagaccgat ttcttggtct tttatgctgt ctgattgact
    36001 gcgtatggcc ttatttttat gctgtggtaa tgaaaaaagc cgtcttattt atcgaatatc
    36061 attagtggag gtaataagat gtattccatc aaaactgatc ataaattaat gcctagagag
    36121 cgtttgattc gactgggtcc agaaaagcta agcaatcaag agcaactagc gatcctactt
    36181 aggacaggta acaaggaaaa gcatgtctta gagttgtctg cttatttatt gtcaagctta
    36241 gatagtctag ctgacttgaa gaaattttct ttacaagaac tacagcgctt atccgggata
    36301 ggaaaggtca aggctattga gattaaggcc atgctggagc tggcagaccg tattcagata
    36361 gcgggacaag cagtagcaga tcctgtctta tctagtgctc aggtggctga aaagatgatg
    36421 attgaattag gagacaagca gcaggagcat ttagtcgcta tttatctcga tagtcaaaat
    36481 aaaatcattg aagaaaagac gatatttata ggaaccgtca gaaaatcaat tgcagagcct
    36541 agagaaattc tttattatgc gtgtaaaaat atggcgacta gccttattgt tgttcacaat
    36601 catccctcag gcctgaccaa gccaagcgca aatgactatc acttcacaga aaaaataaaa
    36661 cgatcatgtg attatttagg acttatctgc ctagatcaca ttatcgttag taagtatgac
    36721 tactatagct ttcgggaaaa atcagattta ttttgagtta gaaactatgg ataaaccaat
    36781 caaagagcct taggtcttct tctctaatag cctgaagcag ctctgggtgc cactggacac
    36841 cgagaaaggg aatatcagga ttgcaggaga taacagcctc gatggtgcca tcgttaggat
    36901 cccttgcaat cactcttaag tcctctgcga cctgctttag gctctggtgg tgaaatgaat
    36961 taatcagcgc tcttggacca tagatagggt acaaaggtga agtcttttcg atcactatct
    37021 cctgtgataa acagtcagag gcagtctttt gccaatggcc ctcaatgtgc tggtttagac
    37081 tgccacctag agcaacattt attaactgca taccgcgaca aatccctaaa attggttttt
    37141 tctgcgctag ggcttcttta atgatggcta gctcaaagat gtcacgctgg ggtgaaaaat
    37201 caccatcaag tgcagctctt ttttcatgat aatatttagg atcaacatgc tgaccaccaa
    37261 taagaatgat tttatcaacc attgcgacat aggatttggc agccgcctca tccccaatcg
    37321 gaagaagtaa gggtaggcca ccagatcttg tcacagcctc gatgaagctt gttggagcat
    37381 aggagcaagg caggttatct agagccttgg tccccctttg gttagcagtt atcccaataa
    37441 ttgttttaga cacgaccttc tccattaatc aagatgattt tggttcataa agtatagcaa
    37501 ggtttgcaac tcgctggtca aatcaacaga ttggacgatc acaccttttg gaacctgtaa
    37561 gtgaagtgga gcaaagctta aaataccgcg aatgccagct tcaatcagtt gatctgcaac
    37621 ctcttgagca tagatgcttg ggactgttag aatagccgtt tcaatgcctg aattatccag
    37681 gtgctcctta atggtagaaa tgccataaat aggaatatca tcaggcgttt tggtgccgac
    37741 cataggatta tcatcagtgt caaatcccat aacaatctgc attttgtttc gatcgtggaa
    37801 gcggtagtga agaagtgcac gaccaatatt gccgcagcca actaaaatca catgcgttgt
    37861 tgagtgatca tttagcaaat ctgcaaaaaa attcattaat tttgtgacat catagccaaa
    37921 tccacgtcgg cctaattcac caaagtaaga aaaatcacgt cgaacagttg cagaatcaat
    37981 tcccatagca tcagcaatct gttttgagct tgccttttca acctgatcag cataaaagcg
    38041 tttaaaaata cgataataga gtgataagcg ttttgcagtc gcttttggaa tagatttatc
    38101 aataaccact tttgtagctc cttctattgt tattttaatg ttatctatca ccattgtagc
    38161 agatagattg tgaaatatgc aactatttga ccattctttt tgtgtttttc gttataaaat
    38221 gacttgacag cacaagcatt ggtatttttc aaacccagtc acctcgagta taaaaaagca
    38281 gacaatgaag cacttgccct ttaggtcagc tgcgatggct gggcttgtct tgttaaaggc
    38341 aaatgtactg tcattgtctg atatttctct gagattagaa gagctcttgt gtgcttagca
    38401 ttctttttta atgaaaatat cacgctcaac aaggctatcc attaaaaagt aaaacttgtc
    38461 ctgtagtatg ctatgctctt cagatttaaa aatgttcacc agtcttagac cggattggtc
    38521 tgttatagct agcttaaagc catctaaatc tttattaatc gtaattttta aagggaagcc
    38581 ctcacccgaa ttagggactt tttccagtag tcgtgttaac tgatagtgac caatcttggt
    38641 ctgactaaag gttgtgtctc ttagggtgta ttttttaatc tttgggctaa tcctgtagct
    38701 gtatttgcag tctttaaggg caatttcttt ttcaaatgcc atatgatcct cctaaaatat
    38761 ttttgagctg ggttgctagt gcgataacgt ctttttgagt attttgctct gaaaagctaa
    38821 ctcgaatagc ttctgtgaga cgatgggact gcttgccgaa ataagctgcc aaaacgtgac
    38881 ttggctcaac agcaccagct gtacaagcag agcctgacga cacagcaaag cctgctaaat
    38941 caagctgagt cagtaataca tgattttggt aaccaggaaa gccgatatta atgatatagg
    39001 gaagatgaca ctcattatga ttgagctgat aagaaatacc ttctaattca ctaagcaaga
    39061 gctgtgatag ctctttagca tgctggtaat gctgtggcag ccttgagaca gcctcatcta
    39121 atgcttgggt catgccgacg atattaatca ggctttcagt gccggctctt tgtttgtttt
    39181 cttgattgcc gccatgtaag aggggggcca actttaagcc tttattgtat aaaaaaccag
    39241 tcccctttgg tccatgaaac ttatgggcag aggcagagag caaatcaatc cccaaatctg
    39301 ccggctgtat tgggaccttg ccaatagctt ggacagcatc aacatgaaag acagcctgat
    39361 gctgctttag catgctacca acagcctgaa taggcagcaa atctcccgtt tcgttgttag
    39421 caaacatcat gctgactaag attgtatcct ctcttaaggc agcttggagc tgatttagat
    39481 caatgattcc atttttagcc tcaaggtagg tcacctcaaa gccaaatcgt tcttccagat
    39541 aggccattgt gcttaacacg gaatgatgct caatagcagt tgtaatcaag tgtttgcctt
    39601 tttcctgatg agctaaggca tagcccttga tagcagtatt gttactttca gtacctcctg
    39661 aggtaaagat aatgtggttt tctgcagctc ctaggcagtt ggcaatagct tttcggcact
    39721 ctcttaattg tttgtttgcc tgccgcccat aagcatgaat actagatggg ttaccaaaat
    39781 catcagccat agcttcagtc atcgccttga tagcagcctg actaagcgat gttgtagcag
    39841 cattatcaaa ataaatcatg attagttagt gctttcaggt ttgtaagaaa acagtggact
    39901 tagtggtttt ctttcgtgaa tgcgaatgat agcctctgca attaaatcac tggcactaag
    39961 ataggttact gttttaggga tacgattttt agtcttgaca gagtccgtga caatgatctc
    40021 tttgattgga gcagtctcta aaatatcagc tgcacctcct gcaaaaatcc catgactagc
    40081 cactgcataa atgtcagttg cgcctgcaca ttctaggatc ttagctgcct ctgcaaaggt
    40141 ttttcctgtg ttgagaatgt catcaatcaa gatagccttc ttgccagcaa catcaccaat
    40201 cacatagcct tcttcgcgct cagcatcgtc ttgtgcataa tcgataatgg caattggaga
    40261 gttaagatac tctgctaagc ttctagcacg cttgatacca gaatttttag ggctgacaat
    40321 aaccgtatca ggtcctgaga ggcccagtgg ataatagtgc tttgcaaaaa gaggcactgt
    40381 aaataaatta tcaactggaa tgtcaaaaaa gccttggacc tgaaccgcat gcaaatcaag
    40441 ggttacaacg cgatcaatcc ctgctttggt cagcatgttt gcgaccagct ttgctgtaat
    40501 aggctcgcga gactttgcaa cacgatcctg acgcgaataa ccaaaatatg gcaaaacaat
    40561 attgactgta ttagcacttg cacgcttaca agcatcaatc atgatgagca gctcccatag
    40621 gttatcgttg acaggaaagc ttgttgattg aatgatataa atatcatcac cacgaactgt
    40681 ttcttcaatg ttaatcatga tctcaccatc agaaaattga cgagatgaga cctttccaag
    40741 cggaatacca gcagccttag aaattttttc agcgattgcg agatttgaag tgagtgagaa
    40801 cagcttgatt tgcttgtcag catatcgttc agtcatgata aaattagctc cttacattac
    40861 attaacgata gaataacagg ttaacagtta ttcaagatta caaatagaca gtactatttt
    40921 aacaaaaaaa cagaaaaatt tcagtctttc tgttgatttt ctgtcctctc ctaggatttt
    40981 ttaagggtct tgctaaagcg agcgaccttg cttttggaat atttaaaggt gatctgatgc
    41041 tgggctaaaa agtggtcaaa atcaaccttt cctcttacag gatcagtcac ctctagctca
    41101 agctcatagt ctttgatacc agcatattga ttataatcca gcgctagctt gccaatagga
    41161 gtatctgcct ctcgacgaat ggtagtcagg tttccgaagg tttttatagc agataggtca
    41221 acgtcaagag tgctgataat atcaaggata gctgattttg gtagctgtcc tgtctgaatg
    41281 atagcttttg cttgggtgtc atcaagctct aaattgtact cgcgattacc aaccttttca
    41341 gggactttta aggttaattc agcaggagca gcaacaaagg tgcgaatgcg aagtgacatt
    41401 ttatgagcct tgagatcaaa atgatcagta tcaatgtaat aatttgtctg ggtaactggt
    41461 gggacatgag tcatttgaga gaggaggcga ttatattcgt cctttgtcag taaggtcttg
    41521 tattcgattt ctaggttagt catgcgaacg ttccttttaa ctatatttta tgctataata
    41581 aattgttatc ttaattttat attaatatcc gaggtttgac aagaaaggag agaaaggatg
    41641 gctttagatt gggaagaatt tttggatcct tatatacaaa cggttggcga attgaaaatt
    41701 aagctgcgcg gtatccgaaa gcagtttcgc aagcaaaacc gttattctcc tattgagttt
    41761 gtgactggac gtgtcaagtc ggttgagagc atcaaggaaa aaatggcctt gcgtggtgtc
    41821 ttggaagaaa atatcgctca agatattcaa gacatcgctg ggcttaggat tatggtgcag
    41881 tttgtggacg atattgagga cgttttgtcc ttgcttagac aaagacagga catgacaatt
    41941 gtttatgagc gagactacat tagaaacatg aaatctagtg gttatcgctc gtatcatgtt
    42001 gtcgttgagt atcctgttga taccattgag ggtcaaaaaa aagtattagc agaaattcaa
    42061 atccgtactt tagcaatgaa tttttgggca accattgagc attccttgaa ctacaagtac
    42121 ggtggtgatt ttccagaaga aataaaaaaa cgattagagg ttacagcaaa aattgctttg
    42181 gagcttgatg aagaaatgcg aaaaattcgt gaagacattc gtgaagcaca attgttattt
    42241 gatcctgtaa cacgtcattt gagtgatggt gtaggaaata gtgatgacac agatgaatta
    42301 tacagataaa gtaaagcgcg ttgctatcat tgcaaacggc aaatatcaga gtaagcgcct
    42361 tgcctcaaag ctttttggcg tctttaagga cgatccgagt ttttacctat ccaaaaaaaa
    42421 tccggatatt gtgatttcaa ttggcggaga tggcatgctt ctatcagcct ttcatatgta
    42481 cgaaaaagaa ttagacaggg tgcgatttgt aggcattcac actggacacc ttggttttta
    42541 cactgattat cgtgattttg aggttgatca attgatagcc aatcttagaa gagacaccgg
    42601 tgagcaaatt tcttacccta ttttaaaggt agttattacg cttgatgacg gtcgcctgtt
    42661 taaggctagg gctctcaatg aagcaactat taagcgtatc gagaaaacga tggttgcaga
    42721 tattatcatt aacaatgtca agtttgaaag ctttcgtggt gatggcatct ctgtatccac
    42781 accaactgga agcacagcct ataacaaatc cttaggtgga gctgtattgc acccaacgat
    42841 tgaggccctt cagctaacag aaatctcgag cctgaacaat cgtgtattta gaaccttggg
    42901 gtcctcagtg attattccta aaaaagataa aattgagctt gttccaaaaa gactaggcgt
    42961 ttatactgtc tctgttgaca ataaaaccta ccacttaaaa aatgtggtta aggtggaata
    43021 ttttatcggc aatgaaaaga ttcattttgt gtcctcacct agccacacca gcttttggga
    43081 aagggttaag gacgctttta ttggggatag tgaatcatga ggtttgaatt tgttgcaact
    43141 aaaaaaacaa aggtaaagac ccttttaaaa gagcacgatg tgtcaaaggg attgctcgct
    43201 aagattaaat acaagggtgg caatatatgg gtaaatggcg ttgcgcaaaa tgccatttat
    43261 ttattggata ttggtgatgt ggtggctatt gatattccaa atgaggagtc ctttgagcaa
    43321 ttgacagcga tttcgcatga ccttgatatt gtgtatgagg acgaacattt tctcattctc
    43381 aacaagcctg ctggctacgc tagcattcca agtgctatcc attctaatac tatagctaat
    43441 tttatcaagg cttattatat caagcaggac tatcccaata aacaggttca tattgtgacg
    43501 cgcttagatc gggataccag tggcttaatg ctctttgcca agcatggcta tgcccatgcc
    43561 agattagata agcagctaca gcaaagagct atcaataaac gctattatgc tcttgtttgt
    43621 ggtcaggaga ggcttccaga tcaaggtgag attatagctc ctattggccg tacggacgac
    43681 agcattatca caagaactgt cacgccaaag ggaaagtatg ctaagacaag ctacaaggtc
    43741 attgcccgct atcctgaaaa tgtctctcta gtggatatta cgctgcacac tggtcggacc
    43801 catcaaatta gggtacattt tgctcatctt ggttttccac ttttgggaga tgatctgtat
    43861 ggtggtcgat tggaccttgg catgactaga caggcgctgc attgtcacca tcttagcttt
    43921 acgcacccat ttacagaaag tagaagcgat catacaatat gcttgacaga tgactttgag
    43981 agcgttatca tagatttaca gaaaaaagat agaggttagt taatgagtat tcgtaattta
    44041 tttggtggtt taagggaaaa aattgtcggc aaaaacatga agattgtttt ccctgaggga
    44101 aatgatgagc gtgttgtacg tgcagcagca cgtctaaagt ttgaaggtct tgttgagcca
    44161 attattcttg gtcaggcaga tgatattcgc agcctgctaa cacagctagg ctttgctgag
    44221 cagcactata caatcattaa cccaaatgat tatgctgatt ttgagaaaat gaaagcagcc
    44281 tttgtagagc ttcgtaaggt caaggcaacg cttgaagatg ctgatagact gcttagagat
    44341 gtcaattact ttggtgttat gctggttaag ctaggcttag cagatggcat ggtttcaggg
    44401 gctattcatt caacagctga tacggtgcgt ccggcgcttc agattatcaa gacaaagcca
    44461 ggcatttcta gaacatcagg tgtctttttg atgaatcgcg aaaatacaga gcagcgttta
    44521 gtgtttgctg attgtgccat taatattgac ccaactgctc aggagctcgc agaaattgcg
    44581 gtaaacacag cagatactgc gaaaattttt gatattgatc ctaaggttgc catgcttagc
    44641 ttttcaacaa tgggctctgc taaagcccca caggttgaaa aggttcaaga ggccgtccgt
    44701 attgctaagg aattgaggcc agagcttgct ttagacggtg agcttcaatt tgacgcagcc
    44761 tttgtaccaa gtacagcagc gatcaaagcc cctgattcat cagtggcagg ccatgcgaat
    44821 gtttttgtct tcccagattt acagtctgga aatattggct ataagattgc tcagcgctta
    44881 ggcatgtttg atgctatcgg accaatcctg caaggattga acaagcctgt taatgattta
    44941 tcacgtggct ctagtgcaga ggatatttac aagctagcta ttattacagc agcgcaagcg
    45001 cttgaaaatg agtctatcaa ttaactgcta atagccatta agttcacaag gcttagctat
    45061 agtagatgtt gcttaaaacg agttggataa gccagctcgt tttttcagaa agtgaggaag
    45121 gaaatgacaa agattgcatt agtaacaggc gcctctgctg gctttggtaa agccattgca
    45181 gagcagttaa tagcccaaaa catcaaggtg atcggagcag cccgccgcat agaaaagcta
    45241 agagagctag aaggtatttt tggttctgag aggttttatc cgcttcaaat ggacgtttca
    45301 gaaccaactg ccattgataa agcacttgca gaattaccta aagaatggca ggccattgat
    45361 attttagtta ataatgcagg actagcctta ggacttgata aggcctatga ggctgatgtc
    45421 gccaactggc taaccatgat taatactaat attattgggc ttatctattt aacacgtcag
    45481 gtattaccgc aaatggtaag cagcaacaat ggcatgatca tcaatatcgg ctcaactgct
    45541 ggcactattc cctatccggg agctaatgtt tatggggctt caaaagcctt tgttaagcag
    45601 ttttcgctta atttaagggc agatttagca ggaacaaata tcagggtgac caatattgag
    45661 cctggccttt gtgagggaac agagttttct catgttcgct ttaagggtga ccatgagcgt
    45721 gttaaagcac tttatgcagg tgcacatgct attcagccaa gggatatcgc aaatactgtc
    45781 tcatggatta ttgatcagcc agagcatgtt aacattaacc gcgtggaaat gatgcctgtc
    45841 tcacaaagct atggttctca gcctgttagc cgtcatgact aagaattaca agagcagatg
    45901 taaaaggatt gtcgaagtgc aacccaaaaa gacttaaagc ctagctgttt tatagcctgg
    45961 ctttaagtct ttttctctaa tttttcttag aaatgatccg aaagagaagg tccagatgtg
    46021 acatctgacc acccaacaat ggcctgccct gtttcttcca aatagtgctg cagcataggc
    46081 ttgaagtcca aaatcatgtc atagacccca acaaattgct tggtatcatc gtacaaggct
    46141 tgatattgct gcatataaat atgatcctgt gaagcagtcg gaataagata cagcttactg
    46201 ccagttgccg ccttgtgcaa atcagtcaag atccaatcct caatgacatc atgcttatca
    46261 gaagcaaaaa aattgccatt aaagcgatga ttatcaaaga tgatctgccc ctgatgatca
    46321 gcaattctag cctgaagggg aagataggtt aaaaaatgtg gggctaaggc ttggtaaaat
    46381 tgcatgaggt atttagcaag tcttaaagtt tgctgactat cagtaaaggt atgatcacta
    46441 acggtaaatc cttgctcttt gtctgcctga ttaaaataaa gtacaggtag tgaggcttca
    46501 aggttctgaa aggtaaaaat ggcctgagcc tttttgagct gctcagtagt cagctgacgg
    46561 acaatagtga tatgaaacag atagctaaac tcttgtgata aggtggtaaa aaaagtcttt
    46621 tgcagattat tcttatcatc aaccagtgct aaggtataaa tcgttttagt cataaggcta
    46681 tcatagcttt attttgttta aatagcaatg aaacagcctt ttagtctaca gacttagttg
    46741 atagcttaat aaaagaaagc aatatgaaaa aatgattaaa gcaaactagt tgacttgtta
    46801 gtttaaactt tttataataa atcaaatgag aagataatat gaggcttagc ctaagctgct
    46861 gagcttatct gataatcatt cttcttagca ctgagataac cccctttatc gattaattgg
    46921 agaatctatg atacgtttta ataatgtttc caaaaccttt ggtcacacca aggtgctgca
    46981 ggagcaaagt tttcaaatac agaatcgcga attttttgtg ctggtcggtc caagcggctc
    47041 tggcaaaaca aagctcttaa aaatgatcaa ttgccttact gaaccaagct ctggcgaaat
    47101 tctattaaac ggaaggccac aaaaagagct agatttgcga gatatgcgct tatctattgg
    47161 ctatgttctt cagcaaattg ccctgtttcc aaaccttaca gttgctgaaa atatcgctat
    47221 tattccagag atgaagaagt ggtcagacaa agagattaga actaagacag aggaattgtt
    47281 agataaggtt ggattgcctg caagggatta tctaaatcgc tatcccagtg atttatccgg
    47341 tggagagcag cagaggattg gtattgttcg tgccatcatt tctcacccca aggtgctgtt
    47401 aatggacgag ccgttttcag ccttggatcc tatttcacgc aagtaattac aggacttgat
    47461 gttaagtctt cacaaggagt ttgatatgac aattgtcttt gttactcatg atattgatga
    47521 ggctatcaag cttggagatc gtgtggctgt tttaaatgaa gggcaaattg ttcaactgga
    47581 tcgaccagat gcgatcatag ctgcgcctgc taatgatttt gtagcaagtc tatttggagg
    47641 tcgtgattat gcctagttta ctgatgacct tttgggatcg ttttggtgat tgggcaaggg
    47701 cattaggaga gcacttgcag atttctcttc tttctttgct ggctgccttg ctgataggca
    47761 ttccgcttgc agctctgttg agtaaaagta agcgctggtc aaatatcatc ttgcagctga
    47821 caggtgtttt tcaaaccatt ccttccctag ccttgttggg actatttatc cctctaatgg
    47881 gaatcggaac tgctccagct gtaacagctt tggttattta tgccatattt cctattttac
    47941 aaaatacgat tactggctta aatgctattg atccaagtct tgtagaggcc ggaacagcct
    48001 ttggaatgac caagtgggag cgactgaaaa tatttgaaat tcctattgct atgccagtta
    48061 ttatgtcagg tgttcggacc tcagcagtga tgattattgg aacagccacc ctagcttctt
    48121 tgatcggagc tggcggctta gggaccttta tcctattagg aattgaccgt aataatgctc
    48181 agctgattgt gattggtgct gtgtcgtcag ccttgcttgc gatagtgttt aacagtcttt
    48241 tgtgatacct tgagaaggcc tcactgaggc gtattgcgat aagctttgct gcgaccttat
    48301 tactgctctt aatttcctat actccaatgt ttgtcaagcg gtttgttaat cagtcaaata
    48361 ctctggtgat tgctggcaag ctaggagtag agccggatat tttgatcaat atctataaag
    48421 agctgattga agaccagtcc aagcttaagg ttgaattgaa acctaatttt ggcaagacaa
    48481 gctttttata cgaggcgatt aaatcaggag atattgatat ttatccagaa tttacaggaa
    48541 ccatcacctc tagcctatta aagaaaaagc ctaagctttc taatgaccct aatcaggttt
    48601 acttagctgc taaggagggg attgctgagc aggatcagtt gacgctttta aagccctttg
    48661 cctatcaaaa tacctatgca gtggcgatgc ctgaaaaaat agctgacgaa tttaacattc
    48721 aaagtatttc agatgtgaag aaatatgaaa aacagctaaa ggctggtttt acactagaat
    48781 ttaaggatag agaggacggc tataagggca tacaggataa gtatgatcta catttatcag
    48841 ttgcaacgat ggagccagct cttaggtacc aagccattca gtcaggaaac attcagctga
    48901 cagacgctta ttcaactgat gctgagatcg tgaaatatca gcttcgagtc ttaaaggacg
    48961 ataagcagct ctttccacct tatcaaggag cgccattgat gaaggcttcc ttactaagaa
    49021 agcaccctca tctcaaaacg attctcaatc agttatcagg aaagattact gaagaggaga
    49081 tgcaagcaat gaactatgag gtgtccgtaa agggcagagc agctagcctt gtggcacatg
    49141 actaccttgt aaaggccggt cttattgcaa gaaccaaata agcaggcatg ctagtcttat
    49201 tctggactgg catgctttat ttatgtgatt tttagtctgt ctggctctgc aaggtgtgtg
    49261 ccaaataacc gctcgtttga tgtgtggtta ttgatttagt agctaaggat tggaatctta
    49321 aaataaaatc cgaacgtttg tctaaaaaaa gctttaaaaa ttgacaaaac ataaacgaaa
    49381 ggataaaata aattaaggaa aggtaacatt ttacctagcg atgcctcgga caagcttgag
    49441 gtcataggaa ggtcatttta tatagaagct tatgtcagct gcagatcagg gaagtccttg
    49501 ctggattagt agctgaatgt tgaaaaagga gagaaatgat gtttaatgac atgcctgtat
    49561 ttgattatga ggatattcaa ttaattccta acaaatgtat catcaatagt cgttcagaag
    49621 cagatacgag tgtaagactt ggtaattata cctttaagct acctgttatt cccgccaaca
    49681 tgcaaaccat tattgacgaa acaattgcag agcagttggc aagagatggt tatttctata
    49741 ttatgcaccg ctttgatgag gaggggcgca agccctttat ccagcgtatg catgagcaac
    49801 agctcatcgc ctctatttcg gttggtgtaa aggattatga atacgatttc gtctcttctt
    49861 tgaaggagga cgcacctgag tttatcacga ttgatattgc tcatggccat gctgatagtg
    49921 tgatcaaaat gattaagcat attaaggctg agctgcctga gacctttgtt atagctggaa
    49981 atgtcggaac accagaggct gttcgagagc tcgaaaatgc tggtgctgac gcaacaaagg
    50041 tcgggattgg gcctggtaag gtttgtatca caaaggttaa gacaggcttt ggaacagggg
    50101 ggtggcaatt agctgctgta cgttggtgtg ctaaggctgc tcgtaagccg attattgctg
    50161 atggcggtat tcgtactcat ggtgatattg ccaagtcgat tcgatttggg gcaacaatgg
    50221 tgatgatcgg ttcactcttt gcaggtcata ttgaaagccc aggcaagatg gtagaaatcg
    50281 acggacagtc cttcaaggaa tattatggct ctgcctctga atatcaaaaa ggggagcata
    50341 aaaatgtcga aggcaagaag attttgcttc caaccaaggg tcatctagct gatactttaa
    50401 ccgaaatgaa gcaggattta cagtcatcaa tctcatatgc tggaggcaga gatttggaga
    50461 gcctgcgtcg tgtgaattat gttatcgtga aaaattctat ttggaatggt gactctattt
    50521 aaagccttgg ctaaagacct agtctaaata aggataagca agctgattga tgctgagaat
    50581 aagcacagcg tgtctatagg acgcctgaat gtctagtagc cagtaaagct tttaggcttg
    50641 ctgattggat aggtcattgt gcctatgtgc agcagggctc tagggactta gataaaaagg
    50701 agacatgatg aggttactgg aggagcgtat cctagctgat ggaactgttt taggtgagac
    50761 gattttgaag gtggatcaat ttttaacaca tcaggttgac tatcgcttga tgaaggaaat
    50821 cggtagagta tttgctgatc aatatgctga tttgggcatt accaaggtgg tcaccattga
    50881 agcctctggt atcgcaccag cagtttatac cgcagaagct cttgaggttc cgatgatttt
    50941 tgccaaaaag cacaaaaata tcacgatgac agagggaatt ttaacagcag aggtttattc
    51001 ctttaccaaa caagtgacaa gtactgtttc tattgcagga ggactgctat caaaagaaga
    51061 tagggttttg attattgatg actttttggc taatggtcaa gcggcaaaag gcttgattga
    51121 tatcattcat caagcagggg ccaaagctgt tggcataggc attgtcattg aaaaatcttt
    51181 tcaggctgga cggcaattgc ttgaggattt gggagtagag gtcacttcat tggctcgtat
    51241 taagcatttt gacaatggaa tagtaagctt tttggaggct gatgcctgat gactgcttct
    51301 tatctctcag cattaagctt tttacttgta tagctatacc agctttattt cagtagctat
    51361 tggctggtga taagggatat tggtatggcg gtgcattacg gcgagccgtg ggcagttgcc
    51421 cttgcggctt tacgatttag tatagactat caagaattga ctgcttcctt tttatcgaga
    51481 tgaatcatta gacagacaat catgatttgg cgtgaaggct gctttcagta aacattacat
    51541 catcaaaaat cagctaggta ttcacttagc tgatttttag tgcttataat gtagccgaaa
    51601 ggctcccttt aacccgtctg agatagtaac ctgaccatct ttggtaatga taatgccttc
    51661 cacctcaggc agcttattta gctgacttag gacaaaggaa tgctctaagc caaaaagacg
    51721 actactccat agctcaccat caagtgagaa ttggctgaca atggttaggc tagccatatt
    51781 ggtcttgata ggatagccgt tgtgaggatc aagaaggtga tgataagttt tgtctttgat
    51841 ttgtaattgt ctctcgccga ttcctgaggt tactacagat ttattgttaa ccttaatcac
    51901 gccgacatgc tgtcctcttt tttgattggt ctgctggatc ccaacgtaaa acaagccatt
    51961 atgtcgttgc ttgttggtgc catgcacaag gacatttcca cctagattga taagagcagc
    52021 agtgataccg tctttaataa gaaatgccat gagcttatca gcaatatagc cctttgctag
    52081 ggcacctaag tcgatagaca tgcccttttc tttcaaaaaa atacttccaa ggctttgatc
    52141 ta
//
LOCUS       DARYJX010000011        50719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYJX010000011 DARYJX010000000
VERSION     DARYJX010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            175..963
                     /locus_tag="TU257_000623"
     CDS             175..963
                     /locus_tag="TU257_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0833658.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TU257_000624"
     CDS             972..2141
                     /locus_tag="TU257_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL0833659.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TU257_000625"
     CDS             2144..2347
                     /locus_tag="TU257_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833660.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TU257_000626"
     CDS             2479..3912
                     /locus_tag="TU257_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0833661.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5110)
                     /locus_tag="TU257_000627"
                     /pseudo
     CDS             complement(3942..5110)
                     /locus_tag="TU257_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5166..5807
                     /locus_tag="TU257_000628"
     CDS             5166..5807
                     /locus_tag="TU257_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL0833662.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5928..6854
                     /gene="cysK"
                     /locus_tag="TU257_000629"
     CDS             5928..6854
                     /gene="cysK"
                     /locus_tag="TU257_000629"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL0833663.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7241..7603)
                     /locus_tag="TU257_000630"
     CDS             complement(7241..7603)
                     /locus_tag="TU257_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL0833664.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7603..9003)
                     /locus_tag="TU257_000631"
     CDS             complement(7603..9003)
                     /locus_tag="TU257_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0833665.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9036..9677)
                     /locus_tag="TU257_000632"
     CDS             complement(9036..9677)
                     /locus_tag="TU257_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0833666.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9670..10674)
                     /locus_tag="TU257_000633"
     CDS             complement(9670..10674)
                     /locus_tag="TU257_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0833667.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10671..11363)
                     /locus_tag="TU257_000634"
     CDS             complement(10671..11363)
                     /locus_tag="TU257_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL0833668.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TU257_000635"
     CDS             complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TU257_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL0833669.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13388..14128)
                     /locus_tag="TU257_000636"
     CDS             complement(13388..14128)
                     /locus_tag="TU257_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL0833670.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TU257_000637"
     CDS             complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TU257_000637"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL0833671.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15478..16413)
                     /locus_tag="TU257_000638"
     CDS             complement(15478..16413)
                     /locus_tag="TU257_000638"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL0833672.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16480..18864)
                     /locus_tag="TU257_000639"
     CDS             complement(16480..18864)
                     /locus_tag="TU257_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL0833673.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18928..19245)
                     /locus_tag="TU257_000640"
     CDS             complement(18928..19245)
                     /locus_tag="TU257_000640"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL0833674.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TU257_000641"
     CDS             complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TU257_000641"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL0833675.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20058..21668)
                     /locus_tag="TU257_000642"
     CDS             complement(20058..21668)
                     /locus_tag="TU257_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL0833676.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21825..22310
                     /locus_tag="TU257_000643"
     CDS             21825..22310
                     /locus_tag="TU257_000643"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL0833677.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22455..23906)
                     /locus_tag="TU257_000644"
     CDS             complement(22455..23906)
                     /locus_tag="TU257_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833678.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPEVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23920..25074)
                     /locus_tag="TU257_000645"
     CDS             complement(23920..25074)
                     /locus_tag="TU257_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL0833679.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25138..25506)
                     /gene="rnpB"
                     /locus_tag="TU257_000646"
     ncRNA           complement(25138..25506)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TU257_000646"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TU257_000647"
     CDS             complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TU257_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL0833680.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25964..26479)
                     /locus_tag="TU257_000648"
     CDS             complement(25964..26479)
                     /locus_tag="TU257_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL0833681.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26555..27163
                     /gene="recU"
                     /locus_tag="TU257_000649"
     CDS             26555..27163
                     /gene="recU"
                     /locus_tag="TU257_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL0833682.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27150..29315
                     /locus_tag="TU257_000650"
     CDS             27150..29315
                     /locus_tag="TU257_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0833683.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TU257_000651"
     CDS             complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TU257_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL0833684.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TU257_000652"
     CDS             complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TU257_000652"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL0833685.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32202..33662)
                     /locus_tag="TU257_000653"
     CDS             complement(32202..33662)
                     /locus_tag="TU257_000653"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL0833686.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33938..35332)
                     /locus_tag="TU257_000654"
     CDS             complement(33938..35332)
                     /locus_tag="TU257_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0833687.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TU257_000655"
     CDS             complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TU257_000655"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL0833688.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36429..36656)
                     /locus_tag="TU257_000656"
     CDS             complement(36429..36656)
                     /locus_tag="TU257_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL0833689.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36766..37509)
                     /locus_tag="TU257_000657"
     CDS             complement(36766..37509)
                     /locus_tag="TU257_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0833690.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37509..38312)
                     /locus_tag="TU257_000658"
     CDS             complement(37509..38312)
                     /locus_tag="TU257_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0833691.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38689..39516)
                     /locus_tag="TU257_000659"
     CDS             complement(38689..39516)
                     /locus_tag="TU257_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0833692.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40024..40479
                     /locus_tag="TU257_000660"
     CDS             40024..40479
                     /locus_tag="TU257_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833693.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41120..42463)
                     /locus_tag="TU257_000661"
     CDS             complement(41120..42463)
                     /locus_tag="TU257_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0833694.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42546..43553)
                     /locus_tag="TU257_000662"
     CDS             complement(42546..43553)
                     /locus_tag="TU257_000662"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL0833695.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43555..45810)
                     /locus_tag="TU257_000663"
     CDS             complement(43555..45810)
                     /locus_tag="TU257_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0833696.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TU257_000664"
     CDS             complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TU257_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL0833697.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TU257_000665"
     CDS             complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TU257_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL0833698.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47194..47610)
                     /locus_tag="TU257_000666"
     CDS             complement(47194..47610)
                     /locus_tag="TU257_000666"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833699.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47630..48877)
                     /locus_tag="TU257_000667"
     CDS             complement(47630..48877)
                     /locus_tag="TU257_000667"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL0833700.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TU257_000668"
     CDS             complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TU257_000668"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL0833701.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50296..>50719
                     /locus_tag="TU257_000669"
     CDS             50296..>50719
                     /locus_tag="TU257_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833702.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14988 a        11590 c         9689 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctg accttgcgct
     4381 ctaaatctct tgtagaggtt gctgttaggt atactgtcac tgcatctgct tttgcagcct
     4441 gatgagcagc atggtttaat tgacgattat tgacaaaggg gaaggcatct acttcgtcaa
     4501 taatgagcag atcaaaagca tggtaaaagg tcatcaattg atgtgttgtg gcaacgataa
     4561 tggggcttct atgataaacc tctgactcag catgcataag gcagacttga caggaaaagt
     4621 cccgcgatag tcgtttttca agctctatgc aaacatcaac tcgtggacta gcaatgcaga
     4681 cccagccacc cttattaaca actgctgcaa tagcttcata catcatctct gttttgccag
     4741 caccagtaac cgcatgaact aaggtgtctt gcttgagctt aacatggtta gtaagctgat
     4801 gagagatagc tgcctgatat gtcgtgagct gtccttgcca cctcagataa tgtccctttg
     4861 gaaaagaagc cggtggaaaa tagagcaagg ggcgatcaga ttggtttcga ccaaaaacaa
     4921 gacaggctct acagtagtaa gcaccgctag gcagctgatg agccttctca attaaactgc
     4981 tacagcgttg gcagtataac gttccctttt tagtgatcat gctttgtaag ctgcaagccc
     5041 aggcagaaac agcctttggg cattgccttt cgggtaaaag acgtccatag taattttcga
     5101 tattctccat accttattat ccgaattatt ttgctaaata tcagcatttt ttgtaaaatt
     5161 ttcttatgga agattataaa actattatga ctgatgggct ttttgaggaa agcatcaaaa
     5221 aatctcgctt tatttgccaa atcaaacgcg tctacacaga agaggaggcc agagccttta
     5281 ttgctgacat caaaaaaaag cactataagg ccaatcattc ctgctctgct atgattatcg
     5341 gagacaaagg acaaaccaag cggtcaagcg atgatggtga gccatctggt actgctggta
     5401 ttcccatgct atctgtctta gaaaggcagg aattaaccaa tcttgtagct gttgtgacac
     5461 gctattttgg aggtgttaaa ttaggagctg gagggctcat tcgcgcttac tccggcgtaa
     5521 ctgcggcagc tattcaggcc ttaaaggtcg ttgaggtaaa aaaacaaact ggactagcaa
     5581 tcagcctcac ctaccctcaa taccaaatct atcctaattt tctggagcaa gaagcattga
     5641 ttgaaatgaa taccgaattt tctgatgtcg tcagaacagc tatttacttt gatcctgagc
     5701 gcttggagag tatttctaag gcattgattg agcattatca tggcaaggtt tcctttgaag
     5761 agatcgaatc gcaaaggatt gaggtccctg ttttgcctgc caattagcat gaacagtgat
     5821 agcgtctctt tatcactacg atagtaaatg gctattttac tttgtcgatt attagctata
     5881 tacttttata taagcatgta ttgatacaag gataaaaagg aggacctatg tcaaagctat
     5941 atcacaacat tacagagttg gttgggaaaa cccctattat taaattgaga aacaccagtc
     6001 cagaggaggc tgccgatatt tatgtcaagc tagaagcttt taatccaggc tcttcagtta
     6061 aggatcgcat agcacttgca atgattgaag ctgctgagaa agcaggcatg atcaagccag
     6121 gtgatacaat cgttgagcca accagtggca atacagggat tggcttatcc tgggttgggg
     6181 ctgcaaaagg ctaccgagtg ctcattgtaa tgcctgagac aatgagtatt gaaagacgtc
     6241 aaatcattca agcttacgga gcagagctcg ttttaacccc aggtagtgat gggatgaaag
     6301 gtgcgattgc taaagcagaa gagattgcca gagagaccgg tgcttggatg ccctcgcaat
     6361 ttgacaatcc tgcaaatccc aaggttcatg aagagacaac agggcaagaa attatcgcgg
     6421 tttttggaga aaaaggactt gatgcctttg tttctggtgt gggaactggt ggcactattt
     6481 ctggcgttgc gcatgcctta aaggctgtta atcctgatat ttctatctat gctgtggaag
     6541 cagatgaatc tgccgtctta tctggtgaag agtcttctcc gcacaagatt caagggattt
     6601 cagctggctt tatcccaaat accttagata caaaggccta tgaccacatc attcgagtag
     6661 cgtcagaggc tgcccttgcc actgctcggt caatcggggc taaggagggc tttcttgtag
     6721 gcatttcttc tggagccgct gtttatgctg ctatccaagc tgctaaggag cttggaaaag
     6781 gtaaaaaggt cttagctata ttaccagata atggtgagcg gtacctgtct actgcccttt
     6841 atcagtttga ttagaataat catataagca ccagccctag cagctagaat aagctttcaa
     6901 gcataaatca tcgctcttac ttagtcacca ttaaaggcca gtcagctagc atatggaaaa
     6961 atgcttactt tgattccttt ttaacaataa acatagcata ccacgcctaa gcgccccaga
     7021 gcttctagct tcttggaaat aggctttcct agccgctttc accacagtaa aaaagactca
     7081 agctagtagg ctaagatgtt caaagaggac tagcaatcac aattggcttt ttttgaagat
     7141 agctttgaga taagtaaggt gactggtcca gagctgatag caaaaaaccg aggaacagtt
     7201 catatagctg tttctcggtt ttttatgttt ccaagtctgt ttacgatttt tcctgcttaa
     7261 agtggtctaa gccttcctca atccaattgg gtaagctggc ttcaagaggc ttaaagccaa
     7321 tcttataacg gctgtttgaa aagcgatgat gacttgacac atgatgcttt tcctcctcca
     7381 aagttctcaa ggacaggctg accttatgac tgtattcgtc atagtcaatg acctgaacta
     7441 aaaccgcctc accaagtctt aggatctgat gaatattatc aataaatccc gtcttaattt
     7501 ctgaaatatg aatgagacct gttgtcccat tttcaagggc aacaaaggct ccatagggtt
     7561 tgattcctgt aatggtccca tgcagcttat cgccaatttt catcaatcaa atacctcgat
     7621 ggcctcaatg acaacgtcct cttttggctt gtcttgtgcc cctgtttcga cagcagcaat
     7681 gttatccaag acctgataag aggcttcatc agccaactga ccaaatactg tatggcgacg
     7741 atccaggtaa ggagtccccc catgttcagc gtaggctgct gcaatgtcct ttggccagcc
     7801 accacgctct aattcctttt gagaataagg aaggcttgta ttttggacga taaagaattg
     7861 gctgccgttt gtatttggtc ctgcattagc catcgaaagg gctccgcgaa ggttgtacaa
     7921 ttcctctgaa aactcatcct caaagctttg accatagatg gattgcccac ccattccagt
     7981 gccagtcgga tctccacctt gaatcataaa atctgcaata atacgatgga aaataacacc
     8041 attatagtag ccttccttag ctagacctaa gaagttagca actgtttttg gagcatgctc
     8101 tggaaataaa gccaatgtca gctcaccatg atttgttttc atcaccactc ttggtccttc
     8161 atggccagcc aaatctagct gcggaaaatg taattctttg tcaatcaaac ctaattcctc
     8221 caaggcatat aaaatgccgt tttcttcaac tgttttagta ataaaatctg ctttttcttg
     8281 taattgtggg tgagaaaccc ccatagcaat gctgatgcca gcataatcaa atagctctaa
     8341 atcattgagc tcatcaccaa agaccaggat attttcaggc cttaagccca aatgctcaac
     8401 aacctttgat acacctagag ccttagaggt gccctttagg accacatcag aggagtgatc
     8461 atgccacctt actaggcgaa gctgctcagc caattcaaca ggtaattgca ggtcatctcc
     8521 cttgtcctca aaggtccaca tttggtagac atcatggtgc tcattgtaat ccgggcatac
     8581 ctctagtgtg gagtaaacct tatcaatagc atcactaatc atctcgttac gagctgataa
     8641 gacagcctcg tgacgtcctg ccatgccata atcaatgccg actgcattgg cccatttttt
     8701 ataggctaca acagtgtctg ctgggatagg tgcctgaaag ataatgtttt tttgattgtc
     8761 cttcacataa gcaccattta gcttaacaca ataatctgcc tgtaaatcct gaacctcctt
     8821 gggcacacca tatctggcgc gacccgaagc aattcctgtt aggatccctt ttttcttgag
     8881 ctctttgaaa accctctgga tagactctgg catatagcct gtgttcttta cgcgcagggt
     8941 atcatctatg tcaaagaaaa ccatcttgat tttcttggcc ttatacttta gttttgcgtc
     9001 catactttcc tccatgcaat agtactatta tagcattaat gatcatcttg aggcactaaa
     9061 tgatgtcgga aagcgtatac aacagcctga gtacgatcat caacctgcaa tttggctaaa
     9121 atatttgaca cgtgagtctt aactgtcttc aaggaaataa aaagctcatc agcaatggtc
     9181 tggttatcat agcccttggc caataaatgc aaaatatcgt attcacgcgc tgtaagctct
     9241 tcatgtaaat taggctgctg atcatgtgcc ttaatcttct tgtcaacctc cgtttcaatg
     9301 gcaagctcgc ccttagcaac ctttctaatg gcatttaaga tttcagctgc acttgatgtt
     9361 tttaacatat agcccttagc tcctgcatca atgacagggt aaattttttc attatcaaga
     9421 taggaggtta acaccaacac ccttgcttcc ttccatttgg agagtatttc tagggtcgcc
     9481 tctacacctc ctaattcagg cattaccaaa tccataacca cgacatctgg tctcaattca
     9541 agggcaagct caactccctc acgaccatta gaagcctcac ctatgacatc aacatcttgc
     9601 tgcaaattta agaagctttt taagcccatt cggaccattt catggtcatc aactaatatt
     9661 acggttatat tactcatctt catctcccat cacaagtggc agtctaatgt ccatcgaaac
     9721 gccctttcct ttttgactaa tcaaacgaag cgttccagcc aggtcattca cacgatcttc
     9781 aatattttta aggccatagc ttaattccct aacctgaccc atgtcaaaac caaccccatt
     9841 atcaaccatt tttagctgta gttctgttgg tgtttggttc aagtacacct caaggcggct
     9901 cgccttagca tgcttgaggg tattgctgat aaattcctga gcgatcctaa agagattatc
     9961 ctctatggcc tttggcagag tgccaatatt ttctttatag acaacctcaa tgccgctttt
    10021 atcagttagt tccttgagaa tcatcgtaaa gccctctgac aggctacgat ttgccaattc
    10081 tgtcgggcgc aggtgcaata ataaaatgcg taaatcattt tgagcatttt gcagcatggc
    10141 ttcaacagta actaattgtt gctgtagctg ctccttatcc atctgatcta ggctcataga
    10201 aacccctgac aaaatcatcg acgaagcaaa caattcttga ctaacagtgt cgtgcaggtc
    10261 tctagcgatt cgtttacgct cctgttgaac aattttttga ctatctaaaa tataagcatt
    10321 ctcttttttc tggatattgg ttgttatatg agacattttc gcagaaagtc tggtcaaatt
    10381 cgtgttgatt tcagaggtct cctccaaatg aattctttga ttgttgagaa tcctgcgtaa
    10441 atttttattg atgctccgct tgctattatc atctaaaata atccacaaca aaagcaacag
    10501 caaggttaca gagatgataa gcagcacaac tgaaaacacc aagcgctcta gctgccataa
    10561 atggctccgc aagtagtcaa aggtgatccc cagattatcc atcacaacaa aaacaattga
    10621 taaaatggtt atagtcgaat aaagccagac caaagcataa tacctttttt tcatcgtcta
    10681 gccacctcga catttcctgc tatagtggat acgataatct taaccttctt taaactgctg
    10741 tcctcggcct ctcctagggt gatggattca tttcgtaaat cgtactcttg aagctcaaaa
    10801 aaatcaacac tagcatagat agagctgacc tctaaggtaa cagccacatc aataggcact
    10861 aggatctttg tgttgccaaa gatctttctg ataatgatga cattgtccat tccagtcaca
    10921 atcacatttg tcagatcaat cgtatcattg ccagaggcac gaataatatt gatatcctca
    10981 aaggaataat aatcactttc atagttagct gcgccaagcc attgattttt gacctgtcgc
    11041 acagtcattt tttcttctgc aaaccgaatg agggcaaatc gattcttctt ttttacctgt
    11101 gaaaaatgat tgataatcac atacacaatc cccaacagaa ccgccataat aatataaggg
    11161 ttcagcataa aaattaagaa taaaagcaat aagctaactg ttagcaaaaa gctattgcgg
    11221 gtatcttgat tataaaaacg cagagccaat aaaatcaaga ccaaaattaa aataaagctt
    11281 gataagtcgt tggccaaaat ggtcataatc cccatagcca gcagcatgca ttcaacaagc
    11341 agaaagaatt gaaatttttt cattagactc cttccattac cctgacattt tatcaaaaat
    11401 taagcaaaaa ttcacccttg agtggcattc tagtaaaaaa gaatacctag cttagcaact
    11461 atgggcaagc cagatattct atatcctatt tacgtttacg gtgttgtaac agcgtcattt
    11521 tgacctaatt cggtatgact gcttgagtct gttgtatctc cagctgatgg attaggagcc
    11581 gaggtatcag agctcgatga gctgcttgat gcacgtgtct cctcagggta gaggtagagg
    11641 ctaatatcac ccttttcaga aaggctaatc tgggtaccat aatacggtgt ttgcccactg
    11701 acaaccgcct ttgagcttgg ggagctcacc tgcacaaagc ctgtcggaga gctggagctt
    11761 ggtacatagg ccttgattct tgcggcatca attcctaaag ctgttagtgt attgactgca
    11821 tctgcatagc tgtactcagt taccattggc atgatgactg tatcacccac tgctacactg
    11881 agggtaatct tggatttacc agctgggtta aatttttctc ctgcgcttgg agactggcta
    11941 ataacggtgt tttcagggta ttcatttgtc acgatacgct caatcttgat ttttgacttt
    12001 ggtacgccat aggtctcagt cagactggtc atcacatctt gataatcctg tcccttataa
    12061 ttttccatct caaagccttt atttccgatc gaaaggtaaa ggtcaacgct ggagcctttt
    12121 cgcttagctg agccagcttg aggatttgtc ttaaccacct gatcctcact aactgtgtca
    12181 ctttcaatct gatggacctt accgaccttt agtcccgcct cctccaagac ctgcttggca
    12241 gcattgagac tagagcctgt cacatcagga accttaaccg tagttggctt ggtcaagacc
    12301 aaataagcaa aaagagccac accaacaaca aaaaaggaaa acaagatttt taagagtgtt
    12361 cctagaaaac gcccattttt tttctttttt tgaggctttt gcagagtatc catctggcta
    12421 gtctgctcaa gtctagcatc aactgccgca gatgcctgac tagcatttga taccttaggt
    12481 gctgttacag gagtcggtgt tacctttggc aagggctttg tgctttcgac atcatcaaag
    12541 acaaccttac gctcacgact gcggttatag ctaagggctg tcatcaaatc cctgctcatc
    12601 tcaaaggtcg agcgataacg gtcacttagc tttttggcag tagcccgaat aacgacgttt
    12661 tccaaggctt gaggcacatt aggattttca tcaatgatag agggcagcgg cttttgaaaa
    12721 tgctgcaaag caatcgtcac agcgctatcg ccatcataag gaatatgccc tgttagcatt
    12781 tcaaagagca taattcccat cgcgtaaata tcactttgaa tcgtcgcttt agaaccacgc
    12841 gcttgctcag gtgagaggta atgcacactt cctagcatag aatttgtctg ggttagactg
    12901 gtctctgcaa aggcaacggc aatcccaaaa tctgtaacct taacaacact tgatttggtc
    12961 aaaagaatgt tttgaggctt taaatccctg tgaacaattc ctttttggtg ggccagagtc
    13021 atggcagaaa gaacctcttc catgattctc accacctcat tgttagataa tggcgcatga
    13081 tcctgaatgt attttttcaa gtcagagcca tcaacatatt ccattactaa aaattgctgt
    13141 ccgtcttcct cgcctatatc ccgaatggca acaatattgg ggtgatttaa ttcagccatg
    13201 gctcgcgctt ctctttgaaa acgcgcaaca gcaacctgat ctgtttgata attggtccgc
    13261 aagaccttaa tggcaacgtc ctcattatcc agaatcaaat cgtttgctaa ataaacatcc
    13321 gccataccac cgcggcctat agattttaga atgcgataac gaccagcaaa tagcttgcca
    13381 atctgaatca ttctgcttcc ccgctttcct tatgcaccaa agcaacggtg atgttgtcta
    13441 ggcctcctct ttggtttgcc aggtcaatca aggcttgatt tttctcatca aggctgatgt
    13501 cttgacataa tatgtcaaca atctcctcat tagcaatcat attggttaag ccatcactat
    13561 taatcactag gtaatcgccc ttttctaaaa ccttgacacc taagtctggc tctaccggtg
    13621 aagcttgacc tatagattgt gtgatgatat ttttttgtgg gtggctagca gcctcctctt
    13681 cggtaatctg accagccttc actagggcat taaccaagga atgatcactg gttaaaagac
    13741 tataatttcc ctcatgaacc aagccgatac gagaatcgcc aatatgggca taaatcgcat
    13801 tagaatctac tagagcaact gcctcaacgg ttgttcccat tcccttatag tcttcagatt
    13861 gtcccaagtc gtagatacgt tggttctctg cttcgatggt tgttaacaac caatccttga
    13921 tctgactaag ctcagtaaaa tctgtcttaa cccactctct acctaggtct gtaacggtca
    13981 tctcactggc aatatttcct gccctatgac ctcccatacc atctgctagg ataacaaggg
    14041 taatgccttt tttattatca aatttgttga taaaatcttg attgtttgag cgcttttgcc
    14101 caatatcggt ttttaatgaa atcttcatat aatcttttct gactaggtca gtctcctcct
    14161 aaatactaca agactcgtct gacttgccca ataaagaagc catcagtctg gtattgctct
    14221 ggtgtaatca taagacaacc gtccttgaca atatctgctt gtgcatgctt gagtgttact
    14281 tgttcaaaat taggatgacg ttgtaaaaat ttgtcaataa cttggaaatt ctcttcatca
    14341 aaaatcgtac aagtgctata ggttattata ccaccttttc gcagcgtttg acaaacgcta
    14401 gacaatatct ccagctgaat ttcctgcaat tgctggaagt cctgcccttc cttgttgtat
    14461 ttaatatctg gcttacgcct gatgaggcct ataccagagc agggagcatc aactaaaatc
    14521 ttatcaaagc tgttcttcgc aaaatgctta tgaacctctc tagcatcaag caccttagtt
    14581 tcaatccgat ctgctacccc tagacgctta gcattttcat tcactaaggc cagcttgtgc
    14641 tcatacaaat caagggccac tactttgccg ctcgtcaaat aagaggcaat gtgagctgtt
    14701 ttccctccgg gtgcactaca agcatctaaa atcatttcct gcccttgaat atccagcgtc
    14761 ggggcaacta gctgactggt ctcatcttgg atcgtaatgt ccccattgat gaaataactg
    14821 ctggcagcaa aattgccagc tctcttggtc agaccagtcc tagcaagtaa tgattgctct
    14881 gatcctgttg cctgcttgat ctcatcaagc tttgtcagat ctgtgacacg tatgctggct
    14941 ctgcttctca caaaaagact ttccatgatt gctacagctc gctcctcgcc aaattggtcg
    15001 atcaattttt tgactagcca gaccggtact gagtaagcaa cagcatagta tttgtttttt
    15061 cgcttgatgc tcttgatatc tggtaagggc ttattggtca gctggcgcaa aacggcattg
    15121 accagcttat ctgctcctct gccatgagct ctcgccttgg caagattaac agcgtcatta
    15181 acaatagcat gagcaggcac cttgtctagg taagccagct ggtaaaggct aagcatcaag
    15241 agataataaa cccatttatc cagcctgtct cggtcctcaa tatagtgagc cagataccat
    15301 tctagggtta tcttcctaga gatagtcccg taaacaatct ctgtgactag agccttgtcc
    15361 ttatcactta aaaactgatt cgccagctgg tgcttcaagg caaggttaga ataggctcca
    15421 tgatcaaaaa tatcctcaac gataagcagc gcctgtcctc tagctgattt tttccaatca
    15481 ttcgccaagg acatcaccca cctctaggct tctgccaata ccatttaaaa agtcaacaat
    15541 aggcatcttt ggcttgcctg ctggttgaac gagcgtcaag gatagagccc cctcacctgc
    15601 tgctacgacc aatgcttttt tagttttagc gatgatttgc ccagcagatc cagagccttc
    15661 agccaattca gcctcataaa ttttgaagcg ctgcccatct aataaggtat gagccaccgg
    15721 ccaagggttc attcctctga tatgattaaa cacctctctt gctggctttg accagtccag
    15781 tctttcttct tctgctgaaa gattgggaga aaaggtggct tggctatggt cttgaggaac
    15841 tggctttagg tcaccagaca agtaatcagg caaggttttc aataataaat ctcgtcctag
    15901 aatggccagc ttatcaaaca tggtaccaac attatcagta tctaaaattg gaaggcttgc
    15961 gcttgatatc atatccccag cgtccatctc cttaaccatc tccataatgg taactccagc
    16021 ttccttgtca ccattgataa tagcataatg gatcggagcg ccaccacgat atttaggaag
    16081 taaggacgcg tgcacattaa cagcaaatgt caccgaatcc aataagactg ttggtaaaaa
    16141 ttgcccaaag gctgccgtta caatcccgtc tgctcctaat gccatgatat ctgctagctc
    16201 ctgtgaacca gatagcttct caggctgaaa aacaggcagc tgatgtgcaa gcgccagctt
    16261 tttaacaggc gtcattgtga tgtctttttt gcgaccaacc gcacgatcag gctgggtcac
    16321 gaccgctaaa atgtcatagg ctggtttttc tagtaagccc tgcaaaacag ttgctgaaaa
    16381 ttggggagtg cccataaaaa ttaatcttgt catctatgtc ctctattttc tttctttttc
    16441 attatagcat agcttggcgc aaagtccggt aaagaacact tacataaagc tctgtggctc
    16501 ctgatcaatg ataaccttta gctcgcgatt atcctgctct tggctccaat caagaatttg
    16561 attcagggta gcttcaagct gatcctcaaa gcgatacttc aaaataatct gataatggta
    16621 aagattgtgc gttcttgcaa ttggctttgg cgttggccct aatattctga tctgatcaga
    16681 caagccctgc ttcaatatgg tcagcagttg ataggccttt ttgaccacct cttgctcact
    16741 cttatgcgat agggtcagac ctactgtgaa ataataggga ggatagccta gctttcgtcg
    16801 aatccccatt tcataagcgt aaaaggcttc aaaatcctgc tttttggcca gttgaatcgc
    16861 gtaatgctca ggattgtagg tctgaatcag gacttcacct ggcttgtctg cacgtcctgc
    16921 acgtcctgca acctgagtca gcaattgaaa ggttcgctcc gatgccctaa aatcaggtaa
    16981 atgcaaggaa gtatctgcat ttaaaacacc tactagggtg acgttgggaa aatccaaccc
    17041 ctttgcaatc atttgtgtcc caagcagcac atcagcatca ccatttccaa actggcttaa
    17101 aatagcctca tggcttcctt ttttacgtgt cgtgtctacg tccattcgta atattctagc
    17161 ttccggcaac acttgcttga gctcatcata ggctttttgc gtccctgttc cataatagcg
    17221 tatgcttttg ccttgacagc tagggcatag cttcggaata gccctttgaa agccgcaata
    17281 gtgacaattc atggttttcg tatccatgtg gagggttaag gaaatatcac aatttggaca
    17341 ttgatcaaca tagccacaat ctcgacacat gataaagcta gagtagccac gcctgttgag
    17401 catcaaaaca gcctgctctt ttctagcaag acgctctttg agtttatcaa tcaaataagg
    17461 ggtgaagctg ctaacctcct gctgaccaat ataatctcga aaatcaacaa tctcaacctg
    17521 aggcatactg gcaagaggat tggctctctc agtcagctgg ataaactgat acagtccctt
    17581 gctggctcta gcgcgactat caatactagg ggtcgctgag cccatcacta aggcagcctt
    17641 atggtgcctt gcacgaatga gagctacatc tctggcatgg tatctgggat tagattcctg
    17701 cttgtaggtg gcctcatgct cctcatcaat aataatggct ccaatatttt ctaaaggtga
    17761 aaaaatagca gagcgagcac cgaccaccac tctagcctgc cctgtcttaa ttttctgcca
    17821 ttcgtcaaat ttttctccat ctgacaaacc tgaatgcata atagcgacct gtcttccaaa
    17881 gcgggaaata aatcgagagg tcatttgagg cgtgagggag atttctggca ctaagacaat
    17941 agctgtcttt ccttgctcaa gcacatgcgc aatcacatga agatagacct ctgtcttgcc
    18001 agagcctgta ataccttcca gtaaaaaggg cttagcctct ctgccaacag ccttcgtaat
    18061 ctggtcaaca gcttgctgct gctgctgatt aagctttaag agtggggctg ccttgatgtg
    18121 attgaaataa tcctcactgc gattgacacg tcgctcctca agctcgatca gctggttggt
    18181 cacaaaatag ctaacaacct ctctagaata atcctgataa agcttggcta gcttatcttt
    18241 ttgtggattg gctaacaaat aagcctttaa ggcttggcgc tttttagccc gatttgaaat
    18301 cttatgctcc tgtaaggcta atctattgac ctgatagtaa gtctcggttt tgattgtctt
    18361 tttgtccttg gctagataag ttgccctaat cttaccagac tgtatcagcc taaggacacg
    18421 tccctcctgc tctggactta gcttagaata aagcaaggaa tccccattag agaaaacatc
    18481 agcaaggtca gccgcagcta agtcagctgt cggggtgagc agccgatcgt aatgagaatt
    18541 aagtaggcta ggaagcattg cctttaagag ggtgattttg taggaaaaga ctgtttgtcg
    18601 taattgctct gctaatgcca cctgctcctg atttaaaaca ggctcagcat ctaaaactga
    18661 ccaaatagcc ttcaattgct gcgttgattg actagaaaag ccaataacaa agccctgtag
    18721 caacctattg ccattaccaa aaggcacatg aacgcgagaa ccaatcttaa ccagagataa
    18781 tagctcatct ggaataagat aagaaaaggg cttatcggtt tgcatcaagg gaatatcaac
    18841 aatgacctgt gctatgtgtt gcattttgac ttcctttcta tcaagaaatg gacctgcaat
    18901 atgaaaaaaa ctaagattga ctcaacctta gattttttct ccctcttctt ctttttcttt
    18961 tgcaatctgc tcttttattt tacgctcttc ttcttctctt gctaaacgct ctgcctcaat
    19021 ccttgcacga acagccgcac gcttagcagc aggatccggg tgaatcacaa cattgcctga
    19081 ctcaatctcc tctagtgcct gaagtgttga tttgacagac ttaaaggact gtgtcggtgc
    19141 agcacctgct tctaattcat gagcacgctt ggcctgtaaa ataacaagtg aatattttga
    19201 tgggacttta tctaataaag tatcaattga aggttttaac atcatgggct ttactctttt
    19261 ctatttctat catctgagag attttgttgt tttaatcatt tgatcatagc gaccaatcac
    19321 acgctcaacg cgaaaatgct cggtctcaat aatacgcttg acacgctctg cagctaaagg
    19381 aacctcgtcg ttgaccacag cataatcata ctctcgcatg agcgcaatct cttccttagc
    19441 tctttcgata cgcttggcaa tcacctcttg gctgtctgtt ccacgaccaa ccaaacggtc
    19501 ctgcaattca tctaagtctg gcggcgttag aaaaatgaag acaccatcag gcaccttagc
    19561 cttgacctgc aaagcaccct gtacctcaat ttccaaaaag acatcaatgc ccttatcaag
    19621 ggtttcgtta acataggtta agggagtgcc atagtaattg ccgacatact ctgcatattc
    19681 tagcatttga ccatttttta ttagctcttc aaattcttct cgtgtgcgga agaaataatc
    19741 aaccccatca acttcacctg gtctctgtgg acgtgtcgtc atcgaaacag aatattcaaa
    19801 tttatgatct ggcgttgaaa aaatctcttg tctcaccgtt ccctttccga cacctgaggg
    19861 gccagagaaa acgattaaca aaccgcgttc agacattgtg ttctccttat tgattgcttt
    19921 ctaatagttt atcaaaaagg ctatcgtttt tcaagacaat tatcagccca atcctaagaa
    19981 agaaaaggaa gagatagacg ccttctcaaa gctagaggct aaactctggc ttttgaaaag
    20041 catacactct ttccttttta tttcgcataa tctattgctc gcaactcacg aataacagtt
    20101 accttgatat ttcctgggta atccaagtta ttttcaatct tttctcttac cttgtgtgag
    20161 agaaccacaa tctcgtcatc agaaatcttt tctggctgaa ccatgatgcg aatctcacga
    20221 ccggcttgga gggcaaagct actttgaaca ccatcaaagc ttgttgcgat ttcttcaagg
    20281 tcacgaagac gcttgatata gttttccaca gattcattgc gggcacctgg acgagcagag
    20341 ctaagggcat cagcagcagc taccagaact gcaataaccg aatccggctc gacatcgcca
    20401 tgatggctgg ctatggtgtt cacaacaaca gggtgctcct tgtacttgcg agcaaactcc
    20461 ataccaatct caacgtggct tccttcaacc tcacgatcaa tagccttgcc catatcatgc
    20521 aagaaacctg cgcgacgtgc aagtgccaca ttttcaccaa gctcgccagc taaaatacca
    20581 gctagcttac caacctcgac tgagtggcgt aaaacatttt gaccaaatga ggtacgaaac
    20641 tgtaagcgcc ccatgatctt aatcaaatcc gggtggaggt taggtgcacc gatctcatag
    20701 gcagcagcct caccatactc acgaatccta ttgtccatct caagacgatt tttctcaacc
    20761 aattcctcga tacgcgccgg gtgaatacga ccatcagcaa tcaaggactc tagggtcata
    20821 cgagcaatct ctcgacgaat agggtcaaag cctgataaaa caaccacttc cggggtatcg
    20881 tcaatgatca catcaatccc tgtcagactc tctagagtac ggatattgcg accctctcga
    20941 ccgataatac gccctttcat gttatcatca ggcaagtgca cacttgtaat cgtctgctca
    21001 gtcacatact caccagccat acgttgcatg gcctgtgcta acaggtcctt agcagtcttg
    21061 tctgtcctgt ccttgatgtc acgctctgca tcacgaatgc gtgttgcgat ctcatgcgtc
    21121 agcttgtttt cagtttccat caggataacc tcacgcgctt ctgcaatggt catagcagca
    21181 actcgttgga gctctgctct tttgtcttcc tcaagttttt caacctgtgc ctgtcgctca
    21241 tcaatgtgct tagatttatc ggtcagactt tgctctttgc tatctagtac tttttcttta
    21301 cttgatagat tttcatcctt acgatcaaga gttagagcac gctctgccaa gcgcgtctcc
    21361 agctgtttaa gctcttgtct ttcagattta aattcctgtt caatttcttc acgatacttt
    21421 cttgcctctt cctttgcttc taaaagtaat tctttacgac ttgctttact ttcacgttgt
    21481 gctgtctttt tgatatgagc ggcatcggcc tttgccttgc cacgaatatc aacagcatcc
    21541 tgttcagcgt ttaaaagagt caactctgca gcttccttcg cagacttgag tctaatcgaa
    21601 ataagtgcat aacctaatat tacaccaatg aggccacaga caagtaacgt tatgatatta
    21661 attaacatgt ctttacctca ataatagttt agttttcatt aacagaaagc catctcttag
    21721 tctatcataa aatgaagatt tagacaattt aaaatccacc tacatttttc taaaatctag
    21781 tgattttatg ttatgatatt gataaaaata aaaaggagtt tcttatgcca aaagaagtta
    21841 ttgttgaaag ctttgagctt gatcatacta ttgttaaggc accctatgta cggctaatct
    21901 ccgaggaatt tgggccccag ggagatgtga ttacaaattt tgatgttcga cttgttcagc
    21961 ctaatcaggc tgccattgag actgccggtt tacataccat tgagcattta ttagccaagc
    22021 tcattcgtca acgcattgat ggaatgattg attgctcccc ctttggctgc cgcacaggct
    22081 ttcacctcat catgtggggc aagcatagct caacagatat tgctaagatc atcacgtcca
    22141 gcctagagga aattgctaca agcatcactt gggaggacgt tcctggcaca accattgaat
    22201 cctgcggcaa ttataaggat cacagccttt ttgctgctaa ggaatgggca cagcttattc
    22261 tcaagcaagg gatctctgat gatccattta accgccatgt cacctcataa aacgaaagcc
    22321 tctcttttct gctaatgtga aggaggcttt taatgtattc aaaaaggtgc caaaggcaag
    22381 gctcaatgcc cttaccttta gcacctgtga taactagagt atccagttca ggatcacacc
    22441 ttgtcttcta agcattaata gtctaagtcc tctgcatgcc ccttgccatt tccgacaaaa
    22501 tagcctgttt tgcaattcaa tgaaaagagg taggtgccat caggcttaaa catgttgtaa
    22561 tagccattcc cattgataat attgaccggc tctaggatat aatcattgcc tgaaatatag
    22621 ccccttgctt gtgaggtagc cacaatacgc tcaagcacac ctggattaaa ggcccaagca
    22681 gggtttcctg tatcagcaat catagcctga ttgtagggca cacgagacag gtcacgctgc
    22741 aatattgaag ggtcatagcc tgtaatgcca tacattggag ccactggagc tggtacagca
    22801 ggaacctccg gagctgcagg gcttgctggt aaggcagaag cagctggagt gctagctgct
    22861 tgggtagcag acctgcttgc tagctgctca cgacctgcct tgatgcttga ttgtagcaat
    22921 gaatcaagtt ttgcattacc agtggttagc gtatcactag ctaggtcatc aaaattagca
    22981 tcagctttga cctcagctgc aatcttttca ccattgacaa ttgcagctgt tgtaaatttc
    23041 ccattaaccg cctgaatagc tgttacttgc tttttcagcc cagtaacctt ttccttagcc
    23101 ttgtcataat aggctgtccc ttcaagcctt tttaaagcag tctccaaatt cggtaactga
    23161 tcaaaggcgc tattttttag ggttgtttta tcattatctg tgaaaaatgt cttgtaaaga
    23221 tcttcaaaag ccttagcatt agcctttgtt ttgttggtct gattagctgt tgatgctttg
    23281 ctccttgctt ttttagaaac agtagccttt gactgaggct tatgcttaga cagctgatag
    23341 atatggttga gggcaaaggc tgaggctaca agggttagcg tggctaacaa aatagcaaac
    23401 agaggctttt tctttttaga cctacgacta gcatagctat ctgataaaat actctctact
    23461 tctgcaggtc gctcgctaac tgcgtcatca gctagctgcc cagtaaaatc actagcagaa
    23521 tcagtagctg ccgctgaagt gtcagctcta gctgctagag gctcaatgaa tgaggtctca
    23581 ccggctggct tctcctctgt tgaagcctcg tccactggct caacatcaac taagccggct
    23641 ttgctgagct cctctctttg ttttttgata aagttatcca gacttgctgt atctaactcc
    23701 atatactttg catcaaactt ttgtgatgac acttcgttac gatgccgctt aatatatttg
    23761 tctaaaacac tatcatcctc ggtaatccct gcttttagct ctgagtcctt gcgtactgcc
    23821 tcaccgattg tcattttttt ggcttcatga agctccaaat tttggctttc tgcctctgat
    23881 tcaaatgctt tgcttttttc tgacacgttt tttacctctc tatatcagat tgcgctttac
    23941 cctctctcca taaaattgat acaaatcaac ccttagagta ccattataaa gcttacgttt
    24001 tttatcagct ttttgaccat atttttgttc aaaatgatca tcactcgtca aaataaactt
    24061 gctccaggta actaatggag caaagacctg taccatctca ttatacaaga tgtctactgc
    24121 tttgtcatca agcaaacgct ctccataagg aggatttgaa atgatgacac cgtttatctt
    24181 gtctgtacgg aaatcctgca agcgcatttg cttaaaggta atgatatcag ccaagccagc
    24241 ctcctcagca tttctcttgg caagctcaac catacgaccg tcaatatcaa agcctgaaat
    24301 atccagctca atatcataat tagcctcttt ttcagcagcg tcacgaacct tttgaacacg
    24361 atctttgtcc acccagctcc attcctcaaa ggcaaaggag cgattaaagc caggagcgat
    24421 attcattccg atgagagccg cctcgataca aaaggtcccc gatccacagg tgggatcaac
    24481 caagggctta tccggaaacc aattagacag cttgaggata gctgctgcca tgttttcctt
    24541 aataggagct cccccttttt ccacccggta gccacgctta aataggcttg agccactagt
    24601 atcaatcatc agggtagcct gatcctttaa gattgagacc tcaattttga actcagcccc
    24661 cacctcttga aggggaatat gctccggtct atgaaaatgc tgctgcaatt ttctgacaat
    24721 ggcttttttg gtaatggctt gaacacttgg ctcgttgtgc agggttgacc tgacacactt
    24781 agcctttgca ataggaaacc tagcacctaa gggcaaataa tgctcccaat ccaaggcaaa
    24841 tacgccctga aacagctcct caaagcttcg tgctgggaac tgacctacaa taatcttaat
    24901 acggtcagcc gctcgcagcc aaagatttgc tttagcaata gcttcaatat cgccttcaaa
    24961 gaagaccttg ccattatcta ctcggcagtc aaatcccaag gcccttaatt ccttacccac
    25021 aacagcctct aggccagctg ctgcagttgc tactaatgta aattgttctt tcatatgact
    25081 ctttctatcc taaccaaata aaagctagca tatgctagct taacctatta tgcaattttc
    25141 tataagccat gttttgttcc agaaataact aggtattatc tccttcgata atcatctgtc
    25201 tactgtttgt caacagtcag gatagcttgt tcgtttccaa ctatcccatg cccctaccaa
    25261 agtttgggtt gctagcttga ggggtttacc gcgttccact ttttacgttt ccataaaaac
    25321 ttcgtcactg tggcactttc agagctactc tggcatatca aggacttagc cttttcactc
    25381 gccgtaatgt gtcaaacaca tccctaggct tatttgttcg cctagcacaa acactaccag
    25441 catcacagcc ggtgctagca tggactttcc tcatagtatt gcaatactac gcgattatcc
    25501 aaaaattgca catctacatt actcaataat ttgctttcca aaaacctctt tttccagctt
    25561 gctaatgcgc tttagcatgt caaaattggt ggctgactgt gctactctgg ttggctgtga
    25621 taccgcctga gagctgcctg ctaaaggatc acgcacctga gccttagcct tttttaaggc
    25681 ttcattttca gcctttaggg cctcgatctg agcattgaaa tactcataat ccttgatgac
    25741 gttatcaagg aattcgtcga cctccttctt atcaaagcca cgcatactgg tcttaaattc
    25801 ttgctcaaaa atgtcctttg gactataaat tatacctgtc attctatact ctccaaacgg
    25861 tcaatctttt tcaaatatca aactttgata tcactactta tggtacagaa aaataaatta
    25921 aaaagcaagt atttaaatac cagtgatttt taaatatcac tagctactca tctgcaatgt
    25981 catttaaacg ctcaaagttt aggaaagaaa gggggtaaca gggctgctcc ttcatagctg
    26041 ctaccaaata gcttaggcgc gtttcgtgct cactatcata aaaaagatag gctccgtctg
    26101 tattgtgaat caaaaagtga tggtagctct ttagctgttt agggctttca tagctgggat
    26161 agctatattt gacaaaatca gtctcccgaa attgctgcag ctgctgctga ttgcgatcat
    26221 tccaagtgct gccatgcgtt tcaaaggcaa aaatagtcgc tgtctttaag gggtaggtct
    26281 ttttgaggtc attagctacc tctaaagccc actgctcaaa ccctaaattc ccagtaaaaa
    26341 taaaccagtc taccccctcc tcaagataag caatcagatc tctttctatc gcttttttga
    26401 taatggcaac tcttttatcc ttttcactaa agatgcccag ctcaaaactt cgatagcctg
    26461 ttacgagaat tgcagtcatt agatgttatc ctttcaaaaa tatgttataa tgtgaatgct
    26521 taaattatta ttaagtcatg atgttaggag aacaatggtt aactaccctc ataatcctat
    26581 tcgccaaaag gtgacccctc ttcaaaagca gcaaaagcac aagcaagtag actttgctaa
    26641 tcgtggtatg tcctttgaag catccattaa tgcaaccaac gcttattact tggccaaggg
    26701 cattgctgtc attcataaaa agccaactcc gatacagatt gtcaaggtag actatccaag
    26761 acgtagtcga gccaagattg ttgaggctta ttttaagcag gcttcaacga ccgactattc
    26821 tggtatctac aaagggcatt atattgattt tgaagctaag gaaacaagac aaaaaacagc
    26881 tatgccaatg aaaaactttc acgcgcatca gattgagcac atggctgctg ttttaaagca
    26941 aaaaggcatt tgctttgtcc tccttcactt tgcgacacta aaggaaacct attatctacc
    27001 tgccaaagca ctcattgatt tttatcagat tgataggggc aacaaatcaa tgccacttga
    27061 ttatatcaga aaaaacggct ttgaggtcaa gctgggagca tttccacagg ttccttattt
    27121 agatattata gaacaaaaat ttttaggcgg tgattacaat taacaatcca aaaatcctta
    27181 aattcctgaa gtatacatta ggtgctatcc ttagccttat cattgtgaca attaccttag
    27241 gtggcctttt gtttgcttac tatatcagca gtgcccctaa gctttctgag gcccagctca
    27301 aatcgaccaa ttccagtctt gtttatgacg gtaataatca tttgattgct gacttgggct
    27361 ctgaaaagcg tgaaaatgtt acagctgaca gcattcctat taatctggtc aatgctatta
    27421 tttctataga agacaaacgc ttttttaatc atcggggggt tgatctctat cgtatcttag
    27481 gtgcagcctt tcacaattta acaagcaaaa caacccaagg ggggtctaca cttgatcagc
    27541 agctgattaa gctagcctac ttctcgacaa acgagtctga ccagaccttg aagcgaaaag
    27601 ctcaggaggt ttggctggcc cttcaaatgg agcgaaaata taccaagcaa gaaatcctga
    27661 ccttctacat caacaaggtt tatatgggaa atggtaatta tggtatgctg acagcagcca
    27721 aggcttatta tggcaaggat ttgaaagatt tgtcctatgc tcagctagcc ttgctggcag
    27781 ggattccaca ggccccaagc cagtatgacc cctacacaca gcctgagaca gctcaaagcc
    27841 gccgaaatat tgtccttcag caaatgtatg ctgaaaagaa cattaccaag gctgagtacg
    27901 aagcagctat cgccacacct atatcagaag gcctacagcc tctccagcaa cgcgccagct
    27961 atccaaaata tatggataat tacttaaaac aggtgatcga gcaggtaaag gctgagacca
    28021 acaaggatat ctttacctct ggtctaaagg tttacacaaa catcattcca gaggctcaaa
    28081 aaaaacttta tgacatttac aattctgagg actatgtgta ttaccctgat gctgactttc
    28141 aggttgcctc aaccgttatt gatgtcacaa atggacacgt tatcgcccaa ttaggaggac
    28201 gcaatcagga taccaacgtt tcctttggaa ccaatcaggc tgtcttaacc gatcgtgact
    28261 ggggatccac catgaagccg atcacagact atggacctgc cattgagtcc ggtgcttaca
    28321 attctacagc tcaaacaact aacgactctg tctactattg gccggggaca cacactcagc
    28381 tctataactg ggaccggaga tactatggtt ggatgaccat tcaagctgct ctcatgcaat
    28441 cacgaaacgt ccctgcagtt agggctctag aggcggcagg tcttagctat gcacagtcct
    28501 tcctcagtga tctaggcatt aattatccag agatgcatta ttcaaacgcc atctcaagta
    28561 acaatagcag ttctgattca aaatacggtg caagcagtga aaaaatggct gctgcctatg
    28621 cagcttttgc caacggtgga ctctattaca agccacaata cgtcaataaa attgaattca
    28681 gcgatgggac cagcaaggtc atcgaaaata agggcaagcg tgccatgaaa gaaacaacag
    28741 cctatatgat gactgatatg ctaaaaacgg tactaaccta cggtacaggt actgctgctg
    28801 ctatcccagg agttgcacag gctggtaaaa ctggtacctc aaactatacc gatgaggagc
    28861 tggcacaaat tgttgagaca catggactat ctcctgatta cgtgggaaca atggcgccag
    28921 atgaaaactt tgtcggctac accaaccgat acgctatggc ggtttggact ggttataaaa
    28981 accgtatgac gccaatttat ggctacagcc tagaaattgc ttctcatgtt tatcgcaaca
    29041 tgatcagcta tctcaccggc ggctacagcg acgattggac catgccaagt gggctctatc
    29101 gtagcggcgg cttcctctac ctaagtggta cctatacaaa cagtagcgat tatacaagct
    29161 ctgtctacaa caacctctat ggtaataaca gctcagcttc aagccaatcc tcagatgagg
    29221 atacaactga agacagccac tcagaagcaa acgacagcac aacgtcatca tcagagcagc
    29281 aatcaagctc caccgatgat aagaaaacca actgataaca aaaaactggt tcaaatgttc
    29341 tgaaccagtt ttttcaatta tttggctaag gcacccatcg gatcccaagg ggcaagtacc
    29401 tgtggttctg cctcataggc tgctaattca tcagctgtta gtaggtcctt gcgaacaaca
    29461 atctggtaag tatactcgtc catccaagca tcagaagcaa caaagtatcc tttgtcacca
    29521 accttgtctc cccaagaatt ttcaaccttc catttgatag gcttaccagt atcatctaaa
    29581 tcaacacctg tcaaaaccat agcatgtgtc attaagcttt cgctgtaatc aaggcgacca
    29641 gccttgtctt ggctcaactg aatatccata cctgcctgaa aatcataggt attaagggct
    29701 agaatcccct tttgacgatc tgatacctga ccaacgtctg aaccaaacca aacggactct
    29761 ccagcctgca tttgcttaat agcaagctcc ttgaagcgct ccatatcaag attaaggtag
    29821 cgcacctcag gactgccaac aacattacca agcatatcaa ccgtataaga tttgccataa
    29881 ggcttatcag ctgttggggc gttgataaca gacacataat cagacagctt tagaccaaca
    29941 tatttttcat aaaatgcctg tggtgtgatg cccttatcag catgatagtg attatcctta
    30001 tcacgataag caaaatcaaa ttgacgaggt ggcaaaccaa gattcatggc taagaaatta
    30061 aagatttcct gaagtagctc ttctttttta gcctgtactg cctgatgatc agcaccagca
    30121 ctgatcacat ctcgaagaat ctgagcgtcc tgacgcaaga gcttattgag gtattgattt
    30181 agctcacgac tattgcttga tgacacagac tctgggtaga ctgattttgg cacaacaccg
    30241 tatttttcaa acagggctac aaccatgtcc cactgaccac cgtcttgctg cggaacgtcc
    30301 aaaagaaact taaccctacg gctagtcaag gcttgatcag cagttgcaat cacctgttcc
    30361 ataaaccagt ttgatttttc gtatttgtcc cagaaaaagg tgtgtgcttg tgacaactca
    30421 aaatcttcta atttaaattc tgaaataagc ttatggcgaa aggtgtttaa ggctgcaaac
    30481 atccagcaac gacctgaagc cttttgatta gagaccttat cctttgtcaa gtcaatggaa
    30541 aagacaaaat cattgtcgat ctcactttgt cttgtctcca aggatttaag caagccattg
    30601 tgagtgatgg cattttcaag agctaaatat ttagcattag cttcataatt agcatatagc
    30661 tgttctgtaa atgtctctgt taatactgac atcattttcc tccaaagata ataaataaca
    30721 acacctaaaa ataaagttga cagaaaaatc cataaatact gtcaatttca ttttcaagga
    30781 ttacttctat tatagacctt atttgatatt cttcaagtaa aaaaattagg ctaacttaat
    30841 tttttaaagc taagcagcag ctttccaata accagacaaa aagccatctc aaaagacgac
    30901 aaaacctgct ggactttgag cacctaaaca tgtcatatgt ccacctcagc atgaactcaa
    30961 agaagctagc tgtgtctggc tatgacttca gtttaatcat tagcttgcct tagccacaaa
    31021 aagaatcgtc tccactgtag caaaagtgct tgatataaca ccatcggcta agtcaagggg
    31081 cccctgatag ttaactgaaa catatggcaa agctaaaacc aaagacttct tctccttaaa
    31141 gcctctggtt tttagttagc tgagcattct cctttatctt ggctgcttta agatagggac
    31201 aaatcaacaa ctaccccaat cccatttaca aaaaagccct aagtcagagc cttcataggg
    31261 ctaagggtga gggaagctct taggcaacag ctactggatt tatgcctaat agaagctcct
    31321 gtccctcctc acctatttaa aatagcattg gtttatctat agcctgtgta ggtttgagga
    31381 tcacttccaa aagtcatcaa aaatagtaat tggcagatgg cgcttgtgct gccctttatg
    31441 ccaccagtct tcaatccttg cctgagcttc agcggaaatc gtatgcccct ctaagtaatc
    31501 gtctatctct tgataagtaa cacctaatgc tacctcatct gcaagtcctg gcttcttatc
    31561 ctctagatct gctgttggca ccttctcata gaggctgggg tcagccttta gcacctttaa
    31621 caaggcctta ccctgccgct tagtcaagcg aaaaaggggt agaatatccg ctccgccatc
    31681 accaaactta gtgaaaaagc ccgtaacatt ttcggcggca tgatctgtcc caatgacagc
    31741 accagctgtt tgaccagcga tagcatactg actaatcata cgctgacgtg ccttaatgtt
    31801 tcccttatta aagtcagaaa tctcaagccc tgccgcctct aaggctctta gctgaccatc
    31861 aacagcctct ttaatattaa ccgtcaaggc ttgatcaggt tgaataaatg ctaaggcttt
    31921 ttgtgcatct gcctcatctg cctgaacacc atagggcaag cggacagcga taaattggta
    31981 ctgctcatca cctgtttcag cgcgcagctc ttcaatcgcc atctgagcta gctttccggc
    32041 taagctggaa tcctgaccac cagaaatccc taagacataa gtctttaaaa aagggtgctt
    32101 taacaaataa gcctttaaaa aatcaaccga ctggcgaatc tcctgcttag gatcaattac
    32161 tgctttgacc tcaagctgac gaatgatatc ctcttgtaat gtcatatcaa atcactcctt
    32221 ttacaggctt ccttgcggat tttgtcaata agatgcatct tattttgcca aacatcaagc
    32281 gcaagatcca cagggtaatg ctgcggattc aagacacgct tatattcgtc ccaaagctta
    32341 tcaaattcct ttctagcata agccttgatg tcttttaagc ttggcagctg ataaacgagc
    32401 tttcctttat caaaaatatc tactagcaaa ggaacagcat caaaatctct gacggtttta
    32461 ttaatgtagg tataagtcgg gtggaacatg tgaatttcct ctaggtcatt gacattaaca
    32521 cctgtaaagg tgatgtaatc gccttctgac ttgccctttt cgcggctggt aattcgccaa
    32581 acctgctttt tacctggtgt tgataccttt tctgcattat ttgatagctt gatagtatcg
    32641 cgcatggtac catctgcctg ctctatcgaa acaatcttat aaaccgctcc cagagctggt
    32701 tgatcatagg ctgtaatcaa ttttgttcca acaccccaaa cgtcaatttt agctttttgc
    32761 attttcaggt tgagaattgt attttcatct aaatcattgg aagcgtaaat cttagcctct
    32821 gtgaagccgg cagcatccag ctgctggcgt acccttttag ataggtaagc aaggtcacca
    32881 gaatccagac gaacacccaa gaaattaatc ttatcaccta attccttggc cacacgaata
    32941 gctgttggga cacctaccct caaggtatca taggtatcaa ccaagaaaat acaatccttg
    33001 tgcacactgg cataggcctt gaaagcatca taatcattac cataggcctg taccagagca
    33061 tgtgcatgcg tgccagacac aggaatgtca aaacgctttc cggcacgaac gttactagtt
    33121 gcgtctgctc cgccaataat ggcagcacgt gtcccccaaa cagcagcgtc catctcctga
    33181 gcgcggcgtg tcccaaactc taaaagtggc tcatcttcaa taacagagcg aatacgagct
    33241 gcctttgtag caatcaaggt ttggaaattc acgatattca aaagagctgt ttctactagc
    33301 tgacattgac ctaaaggtcc ctcaacctga acaataggct cattggcaaa gaccaagtct
    33361 ccctcttgtg ctgagcgaat cgttagctct aaacgaagct ctctgagata ggtcaaaaaa
    33421 gcagggctgt agcctagctc cttcaaataa gccaaatcgg tctcagaaaa ggtcaattgc
    33481 tcaaggtatt ctacgattcg ttgtagacca gcaaaaactg catagccatt gttaaaaggc
    33541 tctctacgaa aataaacctc aaagacagca ttacgattat gaatgccctg ctcaaaataa
    33601 acctgcatca tatttaattg atataaatca gtatgaaggg ttaagctatc atctctgtac
    33661 atataagtaa ctccttaaca taattgttat tattatacca tatttttggc atagacctgt
    33721 aagattcaac taaaatcctc tgctcaagct ttctaaaaaa gaagccttga gctgctatta
    33781 agcctgacat attttttgcc agtaccttcc taaaaagtct atagcacaag ggcttatggc
    33841 tttttaacaa aagcagtttc agttgatagc attcataaaa aaagattgaa gaaattgacc
    33901 aaaatagccc ctttcttcaa tctatttaac tcacacctta gccttttaac gcttttttac
    33961 acttgagctg actgtagcag ccaaagacta gaatccaaat gctagcacca attgccccga
    34021 tataggtgga cttctgtaaa aacagtgaaa taaaaacaaa ggcaaaaaag gctagggtca
    34081 atggtgttgt tagctgataa cttggcatca aataaccatc tggcataaag tcactggact
    34141 gacgatattt ccaatgcgca agcatggtca aagcataaat cgcaatataa acaccagatg
    34201 atgaggccgt aatcagcgaa aaggcatctg caacaccggg caggatatta atcaaggccg
    34261 acaccccaac agcaacagca gaagcaataa tagccctact tggtacccct tgacgagata
    34321 gggtgttaat cctcaaggct ttagtaagag catttggggt ctcattagcg atttgataca
    34381 aatgccgacc tgtcgaatac agggtcgaat ttagggctga tgctgctgat gttaagacca
    34441 caaaattaat taaagcagca gcccatttaa tcccaatcag cttaaagacc atcacaaagg
    34501 gagactcgtc cgtaggcaac tgataccaag gcacaatcgc cataatagac accaaagcac
    34561 caacgtaaaa aatgacaatc cgcatcggaa tctcttggat ggccttgggc aagacctttc
    34621 taggatttgc ggtctctgag gttgtaatac caacaaattc gatggcctga taggcaaaga
    34681 aaaccatctg aaaggccatg aaaaatttca acttcccatt cggaaatagt gaaaaatgat
    34741 ccacaatatt ggcaaggctg gcatgaccga catgcgtttc aaagcccgtt agaaccataa
    34801 aaacggctgt tgcaatcaag gctaaaatcg caacaatctt aatcatggca aaccaaaatt
    34861 cagtctctcc aaagacccgc acagcaatta aattgatgga gctaagcaac accaaaaaaa
    34921 cgagctgaat cagccaagat ggccaagcag gaaaccaaaa ctgaacatag gaggcgacag
    34981 ctgtaatctc tgccatgcca ataaagatca gggaaatcca gtaagaaagc ccagaaaaat
    35041 agccccagcc tggcccaata tattttgtaa tgaaattgat aaaggtatgc tgatccggat
    35101 catagtatag catctcacca atagcccgca tcatcaaaaa cataaagaca cctgtaatca
    35161 tgtaaacaaa gataatagac ggacccgtta aggcaataga acgaccagct cctagaaaga
    35221 gacctgttcc aatagtgcct gctatcgcaa tgagctgaac atgtcggttt tgcagccccc
    35281 ttaccatgcc attctcaagt tctttagtgc ttttagcttc ttttgtagac atttgactct
    35341 ccattcaatt aaaaaaacac cactattata tctgtttttc agaaaatgtt caactttctc
    35401 taaggcttgc aaactaaaaa ggccaaccaa gcctttttag cgttaacctt tttaagatga
    35461 taggctttca atgtaatggt agacgccttg accggcaatg gcaccatctc caactgctgt
    35521 tgtgatctga cgcagctgct tttgacgaac atcaccgaca gcaaaaatac caggaatact
    35581 tgtcttcatt tgatcgtctg tcacaatcca gccctcttga ttggtaatgc ctagctcaga
    35641 taccatttga gtaaccggaa tcaagccgac atagataaag acaccaccaa agtcatggct
    35701 agtcacttga cctgttttga cattttcaat cacaacatta gagaccttaa tatcgtttcc
    35761 ttgaatctcc ttgacaacag aatcccagat aaaatcaagc ttttcgttgg caaaagcacg
    35821 ctcctgcaag atcttttggg cacgcagctg atcacgacga tgcacaatcg ttactttctt
    35881 agcgaactgg gtcaggtaga tggcttcctc aactgctgaa tctcctcctc ctacaactaa
    35941 taactcctga ttgcgaaaga aagcaccatc acagaccgca caataagaaa cacctcgact
    36001 ggtgtactcc tcttctccag caacacctaa aagacgatgc tttgctcctg tcgcgacaat
    36061 cactgtttta gtatcgtagt gcgtatcttc tgtgtacaca cgcttataat caccacaatc
    36121 ctcaaccctt tgaacaatgc cataaatgtt ttcaacctta aatttttcaa gcggctcata
    36181 catctttaac gatagctctg gtcctgaaat gtgatcatag ccaggataat tttcaatatc
    36241 tgatgtgtta ttcatttgac cgccaggtgc cccctgctca ataatgccaa ctcgtaggtt
    36301 actacgtgct gcatataaag cagctgtcat accagcaggt cctgatccaa taatgagtgt
    36361 atcgtacatg ggttaactcc tcttaatagt cttgtcatca ttttaacaat agctacatcg
    36421 tattgcaatt atttcgcctt caataccacc agaatgctca taaaggcaaa ggacaaaatc
    36481 ggaatcgtca aaatagcaac cataatcatc tcatataaaa atgcctgtct ctggagaatg
    36541 gttttatcct ttttggtcac agcacgccat aaaatccaca aaagacaaag catgaccatc
    36601 gtaatagctg ctaacaacag accttccaaa taaaagcgaa aaatttctac taacatcttt
    36661 atctacctga ttaccataac cttttttcat ggcagcttag cttttaagca catacaagaa
    36721 aagcctagcc tacctagacc tttttattat atcaaaagcc ggcttttaaa tatacgtttt
    36781 tgcatagttt gcaaaaaatt cctttgttct tgcttcctta gggtgtctaa agatctgctc
    36841 aggagctccc tcttcaagaa ttttcccctt gtctaaaaaa agcaccctat ctgcaacctg
    36901 ataaacaaaa gccatatcat gactcactaa aatcatcgtt tgacctgcct tggcagcatc
    36961 aataatagac cgttcaacct ctccaaccag ctcaggatcc aaggctgagg taggctcatc
    37021 taataatagc acatctggct tcatggctaa agcacgcgca atagcaaccc tttgcttttg
    37081 accgccagat aaatgacgag ggtaatggtt ttcacgatca gacaagccaa ccttagctaa
    37141 ttctgctcta gctatgtctg ttgcttcttg gtcagacagt tttttaacta tttttaatcc
    37201 ttccttgaca ttgtcaagcg ctgtgcggcg ttcaaagagg ttaaattgct gaaagaccat
    37261 cgctaatttt cgtctaagcg ttagaatgtc ttcttttgtg atgtgttcaa agtcaactgc
    37321 aaagtcatca atcgtaatac ttcctgtatc tggctgttca agataattca tgcttctaag
    37381 gaaggttgat tttcctgcac ctgatgcacc aaccagagct ataacctgcc ctttttcaat
    37441 cgtcaccgtt aaatcgtcta agatcttttg tccagagaag gacttggtta aatgagttac
    37501 cttaatcatt agcgcaattc tcctatcttg ctattatttg ttgggattgg tgctttgata
    37561 gccatgttat attcaattag gcgaccagcc tgttctatca aaatactaat gccccaataa
    37621 actaaggcaa ctgagatgta acgttcaaaa taacgataat ctgctccccc tagaatctgt
    37681 gcctgtgcaa acatttcaac gatacctgca ttgaaggcca gagaggttcc ctttgtcagg
    37741 cctatcaacc cattaatcaa ggtcggtgtt gccacaacag cggcatttgg aatgataact
    37801 cggcgataaa cctgagcaga ggtcattcct aggctcttag cagcctcaat ttcgcctgtg
    37861 tgaacagatt gaatcgcagc tctaatggtt tcactcgtat aagcagcttc attgaaggca
    37921 aaggcggtaa tcgcaaagat agaagccgga atagcgttga tattccaatc aaagccatag
    37981 cgttgattta agaatttcag aaaaagagga ataccatagt agctcagcat tagctgaacc
    38041 aatatggggg ttccacgcaa aaagctaaca aaaaccgctt gaatcggata aagaatgcga
    38101 accctgttga ttttgacaat ggcaaaaacc aaggccaaaa aaagacccaa ggcagcacca
    38161 gctatcgtca aaccaagtgt gattggcaga cgcctgataa tatctggaat ggcatcaaaa
    38221 acagcatgcc agctaaacag cttcccttct gggatcaacg agatgagctt gtcataccaa
    38281 gcccacccac ttgttaaaaa cgtagatgtc atgtatcgcc cctttatact ggtttgtctc
    38341 aatattttca ttttaacatt cttgagatgt catgtaaaat agtaaatccg catgataatg
    38401 ataagaaaag cctatcgcag aggataggac tcaaacaaag gaaaaaaact ctttgaaata
    38461 ccgttaacag tagcctcttg gagctaccaa gcttgaactt gagccgaact ctcaaagcct
    38521 ccaagtggct aattctcaaa gaatatagcc actggtacaa gactaacaat cagctactag
    38581 gccaaaaagg tcaaaagctt ggctagctgg cacagctaac tgcctcaaag gctaggtcaa
    38641 cgaaagattg aagcctgccc agggcttgag ggcttttagc cctgtcaatt aattgacctt
    38701 ggagataaag tctcctccca aaaatgcttg gctgagcttt ctgagctgac ctgatttttt
    38761 aagcttagcc agccttttgt tgacaaagct ctgtagagcc ttaccctttt gatcattggc
    38821 aaacacataa tattccaagc catccttagc agtatcagcc tgctccttga gctttgtcac
    38881 atgcacatca aagccttgct cctcagctac ggttgttaga gaaatagcgt catagaaaag
    38941 aaagtccagt tgaccattct ccagcagctg cagcctttga gtaaatgggg ttgactcaga
    39001 agcataggta aggtgaatag gcttttggtc aggatgggat tggttccatt tttcaaggat
    39061 aagcatgtaa ttggagccag ctattccttg ggttttcttt ccagaaagat cagctaagct
    39121 tttatactgc tgcttaccct ttgttgccag agcataatgc gaggccgaaa tagggcttga
    39181 aaacaaatac ttttcagctc tttccttact atagccaaaa ttattggccc caatctgata
    39241 acgacctgca tcaataccag ccaggatcga tggaaaagga accacctcta tgcttaaccg
    39301 atactttttg gagcctttaa aaaccctttt tagaacctca atatcatagc ctgtaacgct
    39361 atgcttcttc ctataggtaa agggcttagt ggcagcatct gttgctactc tgatcacctc
    39421 tttttgacga gctgtgacct catggctagt cacgactgcc aagagtccta gacttgctag
    39481 caaaaaaaag agtgctcgct gtaattgttt tgtcatacca tactcctatc tcttatacag
    39541 tagccatttt aacaaaaaat gataaatttg aataatatca tttctctatc aaggcaataa
    39601 gaaaatagta tcaaacaagc aattaaaaca gcacattctt catttacctg atcatggatt
    39661 aaccacaaca gacaagcttt agctattagc aggctgccta agccaaaatc aacacctcaa
    39721 gctttcaact gactgatgta aaagctagta gtcacctcta caagaagaaa aagaactgtt
    39781 tgtgtcattc aaccagtagc acccttctta actggtcatt cctatccagc tctactacta
    39841 ggctgtcagt taacgatcag aaaaaaagtt gacctatctg ccttatgaag cctagaaaac
    39901 tagctttcat tctgtttaac attagaaaac gagtaaatag tttaaaataa atttttatta
    39961 ttaaacttta actgttgcta tattaatctt tttacattat aattaagtat aaggaggttt
    40021 tctatgaaaa aggcaatagt atcggttact ttgttaacag tagctgtttt aagcttatca
    40081 acaagattta tctactccac tgattattct gatttaaatc ataaggagat ggcacgtctt
    40141 atccagtcaa gaaaacaacc agtaattaag tatcatgaca atgtaaccat taataaaatg
    40201 attacttacc tagctcaggc taaaagagaa ggcattctga cagagacctt cctcatgaat
    40261 tatattttcg ctggagaggg tgagtacctg actaaaaatt caaggattat tgccgatcct
    40321 gacggagggt attggagtat cctagaaggt tatgagggag atggcggtgt taagactggt
    40381 attgacggcg tctcagagct caatatcttt agtccagaat ctaccagcat cggagagctt
    40441 caagaagcgg tgctagcctg gtatgaggct aataagtaac cgcagcttag ttaaccgact
    40501 gcttcatata atagctaata ttagctaatc ataggcctta taggcattga aatggtcaga
    40561 cccatgctca atgcttataa ggttttttag tgcttaccat ctaaccaaaa ccatagcctt
    40621 cagagagaca ttgagctgaa caagcaaaaa agaggagcaa gctcctcctc aaacattaat
    40681 acaccttaat ctacactccc acagaggaag taatttaagg ctggtgtgtc aaagcgtatc
    40741 aacccgttaa tttcaatcac tattctgaca gccaaaggtg cggctttagt tgttaatagc
    40801 tggttttagt tgccacgctt caaagatagt tgctgtaaca attgaagtag gttcgacaat
    40861 ttcaaatgta acaatacttt tatcacacct tttgcgggag cgtagattga aatccttgca
    40921 cgcaacgaca ggaccatttg acatgggaca ctgaacagag ttgaagcctt taaaaacaat
    40981 ccctaaacag ctttgggacc taatcacagt tccttgactc agctctgtca aggattctgt
    41041 tcatatcagc ttagaatgat cgctaaaaac tttttgatct aatttttctt gaacggatga
    41101 tctttaccaa gcacctgtct taaaagcttt gctttctgga ctgacgctct gctcgtccct
    41161 tggcacgttt ttctgctcgt cgctgcttgc gccgcttttc atcaactgcc cattgaattt
    41221 tctttttata gcccggttta atttttttct tttttttctt aaccaggcca atcatttcag
    41281 tgtctaattt ctgataagct ttttcacgat tctggcgacg atcacgatcg taagtatcct
    41341 gaaactcacc attttttaaa acctttggta taaaggtaat gcctagcttt tccagctcct
    41401 tgatatcaga atcatcactt ggctgataaa aggtaatggc tgtccctggc aggccgtttc
    41461 tacctgtccg ccccacacga tgcacaaaaa aggataggtc ttgaggaatg gcgtcgttaa
    41521 tcacatgact aaccccctca atatcaatac cacgcgccgc caaatccgtt gccacaatgt
    41581 attcaaatgc caggtttttg acttgattca tgatacgctt gcgctctcta ggaggaatac
    41641 ctccatgaag cttggctgcc ttcataccat tagctgctaa aaaggcatgt aagtcatcag
    41701 ctctctcctt ggtattgaca aaaagcatgg ccagataagg ctggatagcc tttagagtcg
    41761 ccaaaatttg ctcattttta tcgcgtccct tggttgataa cagccagttg tcaatcgtat
    41821 ctgcaataac ggtttctgtc ttgatctgtt caatgacagg attggtcaaa tacttcctta
    41881 aaaagggctg tagcttttgt ggaatggttg ctgaaaatac aagtatttgg atagtctttg
    41941 gcagtgctga agcaatctta tccacagtgc ttaaaaagcc catatccatt gtcatatcag
    42001 cctcatcaac aacaaaggta gaggccttat gaatggctaa atctcctgac ttgactagat
    42061 catagatacg acctggcgtt ccaatgacaa gctggggctg actaagcttt aacttgtcaa
    42121 gctgacgctg cttgtctgtc cctccaacgt aattagcaat acgaatctcc tgcttagaat
    42181 gcttagcaat ttgcctgctg gcctcaaaaa tctgtgttgc tagttcccgg ctaggtgctg
    42241 taatcacagc ttgaacctct tctttttcct ccttgagctt ttcaaaaata ggcagcaaaa
    42301 aggtatgcgt ctttcctgag cctgtctttg actcacccac taagtctcgt cctgtactga
    42361 caatcgggat aagacgctgc tgaacctctg ttggctctac aaagccaagc tcatctaggg
    42421 cctcttgaat ataatgctta aagtgataat cgtgaaatga cattatttac ctcgttttct
    42481 ttctgataat actattagtg cttgagatga gcaaaaggcg gtgcctcaag cactgcccca
    42541 gccgcttaca aataaagaat cgctaaaaca atgagactgg ctacaagacc aagagcccat
    42601 aggaaggcat caaccttcca ttcagaccac ttggctgctt taccggacaa gccgcctaat
    42661 tccagatgat gatgaaaagg agtcatccta aaaatccgac ggccttcacc atattttttc
    42721 ttggtgtatt taaagtaagt aacctgaagc atgactgagc ttgtctcaag aacatagaca
    42781 atcccaataa ccagcaaggt ccattcctga cgaagcgcaa tagaaatcgc tgctagcatt
    42841 gctcctaagg ctaagcttcc aacatcaccc ataaaaattt tggccggctt atggttaaac
    42901 aagaaaaagg ccagcaaggc accaaccatg atacctatca agagcaaaac atcaaattgt
    42961 ccctgagcat aagcgataac accataggcc agcaggctaa tcacaacaga taccgaggcc
    43021 agaccatcaa taccgtctgt caggttgacc gcatttgaaa agccaaccac ccaaaaaaga
    43081 acaaagcata ggtataaaaa gcccaaatgc caatgataac caaagacatt aatcgcatca
    43141 ataccacttg gcatgacgtg tatcacataa aagaccaggc ctccaacaat ctgaaacgtg
    43201 aatttttgct tggcagtaag gccttcatta acctgcttga agatctttaa gaaatcatct
    43261 aaaaagccta tgatcccgta aatcaataca atcaacaaga tccccgaaat caagcctagg
    43321 ctttgtccat ctcgaaaata gactaaagca aacacaaagg ataagcttgt agcaacaaga
    43381 agaaaaactg ttcctcccat tgtaggtgtt ccagccttag ccaaatgctg cttaacgtcc
    43441 tcatgcatct gctgcccccc aatttttttc aactggtaaa gccttataaa gtgaggcatg
    43501 gcaagggcag tcacagcaaa ggctatcaga cctgctagaa tggttaaaaa catgttaatc
    43561 tcctaaagtt atggtaattt ttttgacttt tttgagcgct tttccgacat caacgctctg
    43621 tttaacgaca cgtcccgagc ttgatccctt gtacttgata tcaatgccag tccatttagc
    43681 aaaggtagcc acattagcct tagtccagcc gtacatatca ggcatctcat caaaatgatt
    43741 tgataaaatc agaagctgtt ggttagcagc tagattggtc cctgcctttt tagatacctt
    43801 tttaatcttg ctgccattgc caaggacaat agggtgaacc agatttctgc gtagctcatc
    43861 agctgatttt cctgtatctt ggccaacaat atcaggcaac tgataagtag cctcgtgact
    43921 ggtatctaca gcaaccggct tgtctaaagt atccttcatc aaataggctt cctctaaaac
    43981 agggttgata atatcctgcc aaaacaccat tgcccaatgc tctgggtgct tcagtgtgac
    44041 atacatcaga aaatcaggct catcagctgg caccatagca accaccgaat aaatatagtt
    44101 tgtcaagcca ccatctaaat aacctgtacc gtccttagtc gcaatctgcg cagtccctga
    44161 cttgacagca actggtaatt gaccaacctt aaccactgga cctgatgatt tcaaatgaag
    44221 ggttccaaat tgtgggtcag tcccaacgtt aatcatgtat tttcgtgttt cactggcagc
    44281 cttttgggac accggctttc cgacaatctc cttgtctgac acccggtaag tatctgtatt
    44341 tgggtcataa atgcgactaa caaattgagg ctctagcatc acaccgtcat tagagatggc
    44401 tgtaaaggct ctaagcattt gaatttgcgt caccgaaatc ccctgaccaa aagcgctcat
    44461 tgcttgggta acaatattat cagaagggaa aatacctggg tcttcatttt ccaagccaaa
    44521 gcgtgtccgg aatccaaaac ggaatttagt taggtagttc atccatttgt catttcccat
    44581 tttttgctct agcttggtca tgccaacgtt acttgaaaac gaaaagcctt gagcataggt
    44641 catgtactgc cctgtagaaa tcccttcgtt aatcgcccaa tcctgaatgg tagcatcagc
    44701 aatggttaag ccattcgcat tgctaaaggt ctcatcagga ttaaagacct tctcatcaat
    44761 agcagctgcc agagtcataa ccttcatggt tgagccgggc tcaaactgcc cctgatggag
    44821 aatattttgc cagctatagc ttttgctgtt tagcccctcc aaggtgtctg cattataggt
    44881 tggtctttga gtagtcgcta agatttcacc agtcttagca tttactagag tagcactagc
    44941 aagctctcct tgcgccttcg actgaaagac gtccatttgc gtttctagaa aggtttgaat
    45001 aggctctgac agggtggtat aaacgtcctt accatcaact ggctttttca ctgtctttcc
    45061 tgttccaagc agggtattac cgtttctatc cttttgataa gtgatgattc catcttcccc
    45121 agataagatg ctatcaaagg ccgcctccat gcccatcttt ccaactaggc tcttggtacc
    45181 gtcctccttg ttttcctcaa gtgaagcaag accaatcagc tctgaagcaa aggtcccatt
    45241 tggatacata cggctaggac ttgctgaaaa tgcgatcccc ttgattttag ctgcctccat
    45301 agccttttgg atcgttgtca tcgtgctata agaaatacct gagccagacg gaccaaagga
    45361 aacctgaaaa agaccttttt gcttaagctg cttaataacg tccttttcct ccatacccag
    45421 ctgctccttg aggatttgag caaccttgtc atactgagac ggttgaacaa aaagcttctc
    45481 gccagtcgct gacacaaagg acttatcaag aatggcataa atgctatagg tcgtcgagtc
    45541 cacagcgata gctgtgccat tgcgatcata aatcgtgcct cgcttggcct gaacagaaac
    45601 cgtctcttga taaacctttt tggctccatc tgatagctta acaccgaatt tctgatccgt
    45661 cccgataatg atcataaaat taatcataaa gatgaagaaa ataaagatgg ttaagagcat
    45721 catgttttgc cccaccctca agcggttctg aacaggtgtc tttcgatcac gaaccacata
    45781 atctaaaaaa tatctttgcc attttgtcat agcttactcg accttcttaa tgttatcatt
    45841 tcggttacta agccctgctt tgccagcaat atcaacaatg cggtcacgtc gcgacagctc
    45901 attaacctct tgcttggcat tgttaagctc tgtcctttta tctgagatct gcctattgag
    45961 ctgagtgata tgctgctgga gctgcaattt acggctttgc aggtaaataa tgcttacagc
    46021 catcgttact gctgtcagga taagcgtagc ataaaaagcc ttctcaaccc tcgagaaagt
    46081 tctaattctt ttttgcaagg cttttgaaac tgcctgagtt cttttttcat taaccataat
    46141 ctatttccga acttttcttg cgactcgtag cttggctgaa tgtgccctat tgttagccat
    46201 tagctccttt tgacttggta aaatcggctt acgcgaaacc aattcaagct taggcttgag
    46261 ctcatcaggt ataaagggaa gtccctttgg agcatcagct gtgcttgctt ctttaaacaa
    46321 gtgctttgtc agacgatcct ccaaagaatg aaaggtaatc actgagatac ggccatcaag
    46381 ggctagcagc tctatcgccc gctggataga cgcatcagca gcaccaagct catcattgac
    46441 ctcaatacga atagcctgaa agatttgctt ggctgggtgt ccttttttct tgagctcctt
    46501 ggctggctta gctgatttga tcaatgctgc cagctctgtg gtggtgctga ttggcttaat
    46561 ggctctcgcc tgctcaatct tacgagcaat ctgctttgag aacttatcct caccatattt
    46621 aaaaaagatc cgaactaagt cattgaaatc ataggtattg acaacctcat aggctgtcaa
    46681 agccgcctgg ctatccattc gcatgtccaa gggagcgtcc tgcttgtaag aaaagccacg
    46741 ctctctctca tctaactgcg gactagaaac ccctaaatca tacaaaatcc catcaatctc
    46801 tgtaacccca tgctccagca agcgtgcctt aaggtgtcta aaattgtcct taataaaggt
    46861 cacctgtccc ttgtcaatat agggcttgag ctgctcctgc gcgtgatcaa tagccttttg
    46921 gtcctgatca aagcaataca agtgcccctt atcaccaagc agagacagca aataagctga
    46981 gtgcccagag ccaccaaggg tcgcatctac ataaatacca tctggcttaa tatccagcat
    47041 atcaacagct tcatgaagaa gtacagttac atgatgaaat tcgtttgtca tagctctaat
    47101 tgtaccatac ttcaaagggt ttataaatca aaaagtaaga gaaaagggct ttcaaggcct
    47161 aagaaagtcc ctctttatct tacttttttt ggcttagcta tccttgacat caagatgact
    47221 aagagcttgc tgcacagcct catacagcag ctcagccgat tcgagcacct gcttggtctc
    47281 ctttaacacc cgaaaatctg tcaccgaatt atctagccaa atatcaaaga tcttatcctg
    47341 tcttgtatga gataagctag aaggcaagcg caactcacta accttcagct ccttttgata
    47401 cctacagacc agatttctca cgtcccctag gctctcatta atagcactga ttttttgcct
    47461 ttttacccag cttgttagta tcccattgtc gaacaaatca aaaaatcccc acctcttaag
    47521 ctctttcaat gcctcaatga cagactcaag cttaaaagct aatgtcttta ggtctcgtat
    47581 ggtttcttgc ttctttagat cccttgtcat aagcctacct ccttagcagc tagctccgaa
    47641 tctggccatt tccattgatc aggtatttac tgctggtcaa ggcctcaagt cccatcgggc
    47701 cacgagcatg cattttttgt gtggaaatgc caatttctgc tcctagacca aagacaaagc
    47761 catctgtaaa gcgtgtcgag gcattcacat aaacagctgc cgagtcaacc agatcctgaa
    47821 aacgctctgc agcattgata ttagctgtga tgatggcttc tgaatgatga ctggtatact
    47881 gattaatcca agaaatagct tcatcaagag aggaaaccag atgaacagac atgatataat
    47941 ccaaaaattc agccgcataa tcttcctctg tggctaatac agccttgcta aacaaggctt
    48001 ttgcctgctc atctgctcgc cattccacct gctgaacctt gctgatggct gcttcaagca
    48061 tgggaataaa ggtcgctcct accttctcat gaataatcag gctttctgca gcattgcaga
    48121 cgcttggtct ttgcgtctta gcattaatca caaccttaac agccatctct agatcggctg
    48181 cttcatcaac ataaatgtga acattgccaa cccccgtctc aatgactggc accttagcct
    48241 tttccttgac cgtttgaatt aatctggcac ccccacgagg aatcaagaca tcaatataat
    48301 ccgttgcctg catcaattcc tcagctacag catgagaggt atcctcaacc agcaaaacag
    48361 catctggcgt aatagctgat gcctctaagg catttctgat aagcctgacc aaggccatat
    48421 tagagtagag agcatctttg ccacctctaa gaataatggc attattggtc ttaaaggcca
    48481 agctaaaggc gtcaacagaa acattagggc ggctttcaaa aatcatcgca ataacaccta
    48541 aaggcacacg cttttgggtt attttcaggc cgtccagatt tgtatagccc ttaatcactt
    48601 cgccaatggg atcagccaag tctgccacct gtctgacgcc ctgagccatc gcatggatac
    48661 gatctgctgt caggcgtaag cgatcgcaca gaatctctga aatcccatgc tcagccgcct
    48721 tagccagatc cttggcattt tctgtcaaaa tcatatccgt ctgggccact aattcctcag
    48781 ccaaaaaggc aagaaattga tttttatcct tcgttgtcaa ggataccaag gccctactag
    48841 ctgccttagc cctttgtcct agctgttcta ttgtcatcac gcgtcacctc tttctatctg
    48901 tttaaaccaa gtgcctagct tttctccctc caagaccctt aaaatgtctc tagggttggc
    48961 accattcatc aaaatcattt gcccctgatg ctcaaacatc atctgggctg attggatctt
    49021 acttagcata ccaccagttc caaatctgct gcctgcaccg cctgctgagg ctataatatc
    49081 ctctgtaatc tctgtcacat gactcctcaa gcgcgcgtcc tcatagatgg ttggattctt
    49141 atcaaacaaa ccatcaatgt ctgatagcat aatcagcaaa tcagcccttg taatacgagc
    49201 tacgatagct gataagcggt cattgtctcc aaattttgtt gaatgatcca tctcatcaac
    49261 actaacagca tcattttcgt tgacaatggg gacaatccct aaactaatca ggctttcaaa
    49321 ggcattggtg acatttgcca gactttctgg aaaaacaacc acatcacgtg tcagcaaaat
    49381 ctgagacact gtcgtctgat agtgggcaaa aatttgcgaa taaaggctca tcatagcaac
    49441 ctgccccaca cttgaaacag cctgctgctt ggcaagctga cttggtcttt tggccatttt
    49501 caacaggtca agcccaaagc ccatggcgcc agaggaaacc aaaataacct cttttccctt
    49561 attcattaag cttgaaatca caaaggctaa atggtcgatc ttttctaagt taatcttccc
    49621 attagcaagc accagcgagc tggttccaat tttaattaca atacgcttta catcttcaaa
    49681 ttgtcgtttc atcatattag gattatagca taaaaaacag cccagaggac tgttagattg
    49741 aagccaaaat caatcagcct atcagcttga taaaaaaaag gatcactggc tacccattca
    49801 cctaagatat aaaaatccac ctgatagcca ctccaagcag gatttccttt gtgacaccac
    49861 ataccacgct acgctttatc ctattgtaag tttaagtctg atcctcctgc attgtcctgt
    49921 catttttaat gaccatatac caacactaaa gctattgaca aaaacgcaca atacgataaa
    49981 atgaaagcgc aaacagctat atttactacc taagggccag accttgctgt aaagcgcaat
    50041 acctgacaga aagaacacgt ttcagaagta gcaagaacaa gtcacaggca tactgtctgg
    50101 cacattggcg caaaggctac cagtgttcaa caagactgga acgcaaatca ataggctgga
    50161 aatcaagtag gaaaaccgta tcatttaaat ttttggaatc ccaagactca attgttctca
    50221 attagtttgg gggcttagga cgacagagcc tgtcagtcat ctaaagcaat taattagtta
    50281 taggaataaa tcactatggt taaactatca aaaagaagca agatagctat gtcattttta
    50341 attgtctttt gtggtatatt tttcgtcgct caaaaacgat tcggttcatc agaccaatca
    50401 tttaccgtaa ggccagacgc agatttctat atagtcggtt accacaatat tgaaggttat
    50461 caattgacaa atgagcagcc gcaaaaaatt tctgacgcta agctcgaagt ggtcaaaggt
    50521 cagatcaatc aagtggttaa acgagcagag ctttcaaatc gttatctggt cttttccgag
    50581 gaggggccac ctttgggggc aataggaaga cttatcgctc ttgattttca aaaaggcaac
    50641 gtgacgtatc acccaacagc tgattatgcc tttacttcct ccggagtatc accagattat
    50701 tatttcactt ctacagcaa
//
LOCUS       DARYJX010000012        49070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYJX010000012 DARYJX010000000
VERSION     DARYJX010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(175..645)
                     /locus_tag="TU257_000670"
                     /pseudo
     CDS             complement(175..645)
                     /locus_tag="TU257_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            860..1081
                     /locus_tag="TU257_000671"
     CDS             860..1081
                     /locus_tag="TU257_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0833703.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1111..1404
                     /locus_tag="TU257_000672"
     CDS             1111..1404
                     /locus_tag="TU257_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0833704.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2541..4373
                     /gene="lepA"
                     /locus_tag="TU257_000673"
     CDS             2541..4373
                     /gene="lepA"
                     /locus_tag="TU257_000673"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL0833705.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4915..5352
                     /gene="msrB"
                     /locus_tag="TU257_000674"
     CDS             4915..5352
                     /gene="msrB"
                     /locus_tag="TU257_000674"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0833706.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5640..6659
                     /locus_tag="TU257_000675"
     CDS             5640..6659
                     /locus_tag="TU257_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL0833707.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            7003..7428
                     /locus_tag="TU257_000676"
     CDS             7003..7428
                     /locus_tag="TU257_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL0833708.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7443..7934
                     /locus_tag="TU257_000677"
     CDS             7443..7934
                     /locus_tag="TU257_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0833709.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            7952..8761
                     /locus_tag="TU257_000678"
     CDS             7952..8761
                     /locus_tag="TU257_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0833710.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8758..9585
                     /locus_tag="TU257_000679"
     CDS             8758..9585
                     /locus_tag="TU257_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0833711.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9775..11409
                     /locus_tag="TU257_000680"
     CDS             9775..11409
                     /locus_tag="TU257_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0833712.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11413..12198
                     /locus_tag="TU257_000681"
     CDS             11413..12198
                     /locus_tag="TU257_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0833713.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12222..13232
                     /locus_tag="TU257_000682"
     CDS             12222..13232
                     /locus_tag="TU257_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0833714.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13485..15269
                     /gene="uvrC"
                     /locus_tag="TU257_000683"
     CDS             13485..15269
                     /gene="uvrC"
                     /locus_tag="TU257_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL0833715.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15397..15999
                     /locus_tag="TU257_000684"
     CDS             15397..15999
                     /locus_tag="TU257_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL0833716.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16080..17489
                     /gene="pepV"
                     /locus_tag="TU257_000685"
     CDS             16080..17489
                     /gene="pepV"
                     /locus_tag="TU257_000685"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL0833717.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17756..19132)
                     /gene="mnmE"
                     /locus_tag="TU257_000686"
     CDS             complement(17756..19132)
                     /gene="mnmE"
                     /locus_tag="TU257_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL0833718.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19404..19625
                     /locus_tag="TU257_000687"
                     /pseudo
     CDS             19404..19625
                     /locus_tag="TU257_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            19748..20062
                     /locus_tag="TU257_000688"
     CDS             19748..20062
                     /locus_tag="TU257_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0833719.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            20067..20399
                     /locus_tag="TU257_000689"
     CDS             20067..20399
                     /locus_tag="TU257_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL0833720.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            20401..21999
                     /locus_tag="TU257_000690"
     CDS             20401..21999
                     /locus_tag="TU257_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833721.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            21993..22679
                     /locus_tag="TU257_000691"
     CDS             21993..22679
                     /locus_tag="TU257_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833722.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            22701..23387
                     /locus_tag="TU257_000692"
     CDS             22701..23387
                     /locus_tag="TU257_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833723.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            23409..24086
                     /locus_tag="TU257_000693"
     CDS             23409..24086
                     /locus_tag="TU257_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833724.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            24093..24407
                     /locus_tag="TU257_000694"
     CDS             24093..24407
                     /locus_tag="TU257_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0833725.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            24855..25538
                     /gene="rpiA"
                     /locus_tag="TU257_000695"
     CDS             24855..25538
                     /gene="rpiA"
                     /locus_tag="TU257_000695"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL0833726.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            25616..26827
                     /locus_tag="TU257_000696"
     CDS             25616..26827
                     /locus_tag="TU257_000696"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL0833727.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKSLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            27040..27849
                     /locus_tag="TU257_000697"
     CDS             27040..27849
                     /locus_tag="TU257_000697"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL0833728.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            27940..28725
                     /locus_tag="TU257_000698"
     CDS             27940..28725
                     /locus_tag="TU257_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL0833729.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(28858..29766)
                     /locus_tag="TU257_000699"
     CDS             complement(28858..29766)
                     /locus_tag="TU257_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0833730.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            30106..30555
                     /locus_tag="TU257_000700"
     CDS             30106..30555
                     /locus_tag="TU257_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833731.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            31176..31868
                     /gene="pyrF"
                     /locus_tag="TU257_000701"
     CDS             31176..31868
                     /gene="pyrF"
                     /locus_tag="TU257_000701"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL0833732.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            31928..32563
                     /locus_tag="TU257_000702"
     CDS             31928..32563
                     /locus_tag="TU257_000702"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL0833733.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            32615..33358
                     /locus_tag="TU257_000703"
     CDS             32615..33358
                     /locus_tag="TU257_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833734.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            33593..35047
                     /locus_tag="TU257_000704"
     CDS             33593..35047
                     /locus_tag="TU257_000704"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL0833735.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            35167..36033
                     /locus_tag="TU257_000705"
     CDS             35167..36033
                     /locus_tag="TU257_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0833736.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            36061..36714
                     /locus_tag="TU257_000706"
     CDS             36061..36714
                     /locus_tag="TU257_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0833737.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            36845..37252
                     /locus_tag="TU257_000707"
     CDS             36845..37252
                     /locus_tag="TU257_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833738.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            37264..37917
                     /locus_tag="TU257_000708"
     CDS             37264..37917
                     /locus_tag="TU257_000708"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL0833739.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            38149..39423
                     /locus_tag="TU257_000709"
     CDS             38149..39423
                     /locus_tag="TU257_000709"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL0833740.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(39477..40124)
                     /gene="plsY"
                     /locus_tag="TU257_000710"
     CDS             complement(39477..40124)
                     /gene="plsY"
                     /locus_tag="TU257_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL0833741.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            40257..42206
                     /gene="parE"
                     /locus_tag="TU257_000711"
     CDS             40257..42206
                     /gene="parE"
                     /locus_tag="TU257_000711"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL0833742.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            42308..43123
                     /locus_tag="TU257_000712"
     CDS             42308..43123
                     /locus_tag="TU257_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL0833743.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            43598..46057
                     /gene="parC"
                     /locus_tag="TU257_000713"
     CDS             43598..46057
                     /gene="parC"
                     /locus_tag="TU257_000713"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL0833744.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            46155..47180
                     /locus_tag="TU257_000714"
     CDS             46155..47180
                     /locus_tag="TU257_000714"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL0833745.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            47248..47478
                     /locus_tag="TU257_000715"
     CDS             47248..47478
                     /locus_tag="TU257_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL0833746.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            47539..47619
                     /locus_tag="TU257_000716"
     tRNA            47539..47619
                     /locus_tag="TU257_000716"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47573..47575,aa:Tyr,seq:gta)
     gene            47658..47729
                     /locus_tag="TU257_000717"
     tRNA            47658..47729
                     /locus_tag="TU257_000717"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47690..47692,aa:Gln,seq:ttg)
     gene            47857..49059
                     /gene="rpsA"
                     /locus_tag="TU257_000718"
     CDS             47857..49059
                     /gene="rpsA"
                     /locus_tag="TU257_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL0833747.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        14118 a         9097 c        11456 g        14399 t
ORIGIN      
        1 ggcataattt cacctcgtga cgataccgtt acttcttttt gaccaagaaa agaaaatgaa
       61 agtaaaaata tgacgaataa tgttaatggt ataataagaa ttatcgcaaa attatgatag
      121 cgtcgctgat aaaattcagc acttctaaac agatttggat tcatgaatat ctccttactt
      181 actaaataaa tgatgataga agccttgatg cgtcattaat tcgttatgcg aacctatctc
      241 gattattttt cctttatcaa gtacaacaat ttggctagta cgttcagcag tactaagacg
      301 atgggcaacg aaaataatcg ttttctcggt cattgacatt aggttatcaa tcactttttt
      361 ctccgttaag acatctagtc cgcttgtcgc ctcatcgaga attagaatag gagacttggt
      421 taataatgct ctagctaatg caattctctg tttttgtcca ccagaaaatc ctgccccatc
      481 agatagttct gtctgatagc ccataggcat ttgttcaata tcttctctaa tttctgccat
      541 atcacaggca ttgataatat cctcttgagt aatcgcttgg tttgcaccga gagtaagatt
      601 ttctaaaatt gatccactaa aaatataagc ttgttgaggc agatattggt tatcgaaacg
      661 tcctaaatgg taatctgaca aatctatcaa attatctcaa acggttgaat ttaagtctta
      721 agcggtaaat ttttcccatt taggacgttt cgatgactgt ttaggaaatg gagaacaaat
      781 tttaaccgaa agtgttatac taagtctgtc aagcttgcaa ccggacaaaa taaaaacaca
      841 tataaaggag gtattcgtca tggatacaaa atttacagcg ttgactgaag agcaattgaa
      901 atcagttgag ggtggaaaaa atggagttgt aaaattacct ggagggaccg gtgtatattg
      961 ttggaataca ggaaaaaata gtgcaaaatg tggtatggac tggagtgtgg caggaccata
     1021 tgttggtaag ataattgtca atggttgggt taaccatgga ccttgggcaa gtcgtccata
     1081 attttaattt atatagagag gtgtgaaatc atgaatgaaa gagatttagt acagctgata
     1141 gaacagactc taaaagatga agaggtgcaa aataatgtca cttataggaa tcttttggaa
     1201 gaaagtctcc agcaattatc actcaaaaag cctgtgtatt tagttagtac caggttagca
     1261 ggacatattt caacctatct aatgacaaat cattatgagg caccaaaagc gattatagtt
     1321 cttgctcaat ctatcgcatc aaccccagct aaacatagag gtttaatttc tataccattc
     1381 tggttaagta atatatttcg ttaaaaaata ttttcagatc aggatttaga aggagttgta
     1441 gattggcaat gcactcataa aataagacac attttttgga gttttttgct tgaactccta
     1501 acttttacat tagtctataa acagtcaaag gaagttcttt caatctctca aattgcaaaa
     1561 caattttggc tatattttaa aagtacaatt ttgattccaa ttttagttac aatcattctt
     1621 ataaaggaga ttttgtcaag tacattacaa ataatgattt atttttacct taatgttgtt
     1681 gtcatgtgct acgctattgg aatgatctta tcgttaggtt atgtgatttc acccaagcac
     1741 tctatattca ataaaattaa aaatataaaa ttaaataata gagtatccca agagattgcc
     1801 gaatcccaat ttaccagtct tttagagcga agagcgactt gaagaaactg ataaatttat
     1861 ttggttttct gctaaaaatc ctgccaaaaa atctttggca ggatttttat tttactaaga
     1921 gatatttagg agtggctttg tcatttaatg cagattatga tatagcagga gacatattgt
     1981 tgaagctgtc tatgtcactt ttggtggcag gtaggtctta ttggaattgg tgacttatga
     2041 catttatcgg tggctgtaag cgtttgactt tttcacgttt catagtggtc cgctctggaa
     2101 tgagtgggta ttttttcaga atatgatcaa agatagatga catgttttac agcaggctat
     2161 agctggtatg atttgtttaa aaaatcaagg ccaatgataa gtgctgggtg acataagtct
     2221 tatggcttta cttcttgtta gcttgtgtca gcaggtgctg agtcaatcgt tgtaggaatt
     2281 atcgtaaacc taacagtagc tgctgttcta tttgtttatt ttctggtttc tattcaaatt
     2341 tctaaaatgc tagggtaaca aatatgaaac aagcaagtgg cgtactgcga acagcttgat
     2401 aacttattgc ctgcttaaag agggtgctgt tatgcttggt tttattaggc ttatggcatg
     2461 ggattaaaag gttgctgtag cgccattgtc attattttgg tacaataata ggtaaaagac
     2521 taaatgtata ggaaaataga atgaacagtc aagaattaaa aaaacgtcag gagaacattc
     2581 gtaatttctc tattattgcc cacattgatc atggtaagtc gactcttgct gaccggattt
     2641 tggaaaagac agaaacggtt tcaagtcgtg aaatgcaggc acagctcctt gattcaatgg
     2701 acttggagcg ggagcgtggg attaccatca agctaaatgc gattgagctg aattataagg
     2761 ctaagaatgg tcaagattat atttttcact tgattgatac accagggcat gtggacttta
     2821 cctatgaggt gtcccggtca ctagctgcct gtgagggtgc tgttttagtg gtggatgctg
     2881 ctcaggggat tgaggcacag accctagcaa atgtctatct ggcgcttgat aatgatttgg
     2941 aaattcttcc agtgatcaac aagatcgatt tgccagcagc tgatcctgag cgggttcgtc
     3001 aggaaattga ggacgtgatt ggtctagatg cttcggaggc tgtacttgcc tctgcaaagt
     3061 ctgggattgg tattgaagat attttagagc aaattgttga aaaggttccc gcaccgtctg
     3121 gtgatgttga tcaaccgctg caggccttga tttttgattc ggtttatgat gcttatcgtg
     3181 gggttatcct gcaggtgcgt gttgtcaatg gtatggtcaa gccaggtgat acgatccaaa
     3241 tgatgtcaaa tggaaaaacc tttgatgtga ctgaggtggg gatttttacc cctaaggcta
     3301 ttggtaggga ttttcttgct actggtgatg ttggctatat tgcggcctca atcaagacag
     3361 ttgctgatac gcgtgtcggt gatacggtca ctctggctac aaatcctgca gcagagccct
     3421 tgcatggcta caagcagatg aatccaatgg tgtttgcagg gatttacccg attgagtcta
     3481 acaaatacaa tgatcttcgt gaggccttag aaaagcttca gcttaatgac gctagcttac
     3541 agtttgagcc tgaaacctcg caagcattgg gctttggttt tcgttgtggc tttcttgggc
     3601 tgttgcacat ggatgtcatt caagagcgtt tggagcgtga attcaacatt gatttgatca
     3661 tgacagctcc gtctgttgtc tatcatgtta atataactga tggtgacatg cttgaggtct
     3721 ctaacccgtc agaatttcct gatccaacta aggtagatag tattgaggag ccttatgtca
     3781 aagcccagat catggtgccg caggagtttg ttggtgctgt tatggagttg gcccagcgta
     3841 agcgtggaga ttttgtgacg atggattata ttgatgacaa tcgtgtcaat gtgatttacc
     3901 atattccctt agctgaaatt gtgtttgact tctttgataa gctgaaatca tcaacgcgag
     3961 gctatgctag ctttgactat gaaattgctg aataccgtcg ctcgcagctg gtgaaaatgg
     4021 atattttgtt gaatggtgat aaggttgacg ctcttagctt tattgttcat agagcatttg
     4081 cctatgagcg cggtaagctg attgttgaga aattaaagaa aattattcct cgtcagcaat
     4141 ttgaggtgcc gattcaagcg gctattggtc aaaagattgt ggctcgctct gatatcaagg
     4201 ccttacgcaa aaacgttctt gctaaatgct atggtggcga tgtttcccgt aagcgtaagt
     4261 tgcttgaaaa gcaaaaggct ggtaagaagc gtatgaaggc tattggctct gttgaggtgc
     4321 cgcaggaggc cttcttgagc gtcctatcaa tggacgatga gagtaagaaa tagtgacatg
     4381 ttaagtaagg agctggatca tgcgatctgg ctcttatgct tgatgtctcg ataggctaga
     4441 aaatagggct tgtgtcatga taggcttgta tgtttgagat ggtttggaac ataatgactc
     4501 tatcatatct gtagtggatt gacaaagagc cgtaaaccat tgatatttgg atagttaatt
     4561 tcgagttatt ctgtagtact ctcttaaggt ctttcatatg agcttttcta atgttggttt
     4621 ggttgctttt catgataagt catatgggat ttttttggta tactgaaaaa agcctatagc
     4681 ctctacagtg gcgtctccct ctacagagat gatagagcca gagtgattgt tacgatctgg
     4741 agatgtggcg ctaggcatta atgcaggagg acttaaccag attgctgtta ggcttgaaat
     4801 cttaagctat attgattgtc agcttgattt agagaagtct aagtttatgg ctcacaaatg
     4861 ctcggtcttt ttgttacaat agagttaatc agttattttt ataaggagac agctatggaa
     4921 tctaaggaag agcttcgcca gcgtattgga gatttggctt ttgaggtgac tcagcatgca
     4981 gcgaccgaaa gagcctttac aggtcagtat gatgattttt ttgagaaggg gatttatgtt
     5041 gatgtggtga gcggagaggt gctcttttcc tctttggata aattcaattc tggctgcggc
     5101 tggcctgcat tttctaagcc gattcagcat cgtatggtaa ccaatcacca tgattcatca
     5161 catggcatgc ggcgtgttga ggttaaaagc cgcgaggctg gctcccattt ggggcatgtt
     5221 tttaatgatg gccctaagga ggcaggaggc ttacgctatt gcattaactc cgccgcgctg
     5281 aaatttatcc cctatgatca aatggagcaa gagggctacg ccgaatggtt agggattttt
     5341 gataagagct aggaattgct agcggccaat gaaaaggtag agctcttagc caatgctagt
     5401 ggctaaatca aagaaataaa aaggtggcta aagtacatag aaaaaagagg taagcagatt
     5461 ggcaggtggt caatctgctt tttgtgagga gactttcagc ctgctttgcg ctaaaaagta
     5521 tgaaaccaat aaaccaccta ctatgcgggt gtgtgtcggt ggttagctta agttttttca
     5581 gttcggtttt acaagcttct ctaaaaggac tataatagct aatggaaaag gagattcata
     5641 tgctaacatc tttagaaaaa ttaccgggcg ttttactgtg cttgctgtta gcactgcctg
     5701 cctggtattt gggaagctta tttcctatta ttggagcgcc agtttttgct attttattgg
     5761 gaatgctatt ggcgcttgtc tatcagaagc gtgactacac taaatctgga atcgcattga
     5821 cgtccaaata tattttgcag ctggctgtgg ttttcttggg ctttggctta aacgtgacac
     5881 aggttttagt ggttggcttg caatccctgc cgattattgt agtaacgatt gtgactgcct
     5941 tgggcataag ctatttgttc aaaagatggt taaggctacc agccaagaca gctatcttag
     6001 ttggtgtggg ctcgtctatt tgtggtggct ctgctattgc agccacagct cctgtcattg
     6061 atgcgcagga cgatgacatt gccaaggcca tttcggttat ttttttgttt aatatcttgg
     6121 cggccttgct atttccagct ttgggtcaga tgcttggctt atcaaatcat ggctttgcta
     6181 tttttgctgg aacagcagtc aatgatacct catctgtaac agctacagcg acagcctggg
     6241 acgctattca ccagtctaat acgctagatg gggcaaccat tgtcaaatta accagaacgc
     6301 tggctattat tcccataaca cttggcttat ctatttacca aaccaagagc aggcaggcac
     6361 atacgacaga gggttccttt agcctcagaa aggcttttcc gacctttatt gtctttttct
     6421 tgctagcttc cttgataacc acctttgctg ctagcttagg tctgccaatg gcaatctttc
     6481 atcagcttaa gctactctca aaattcttta tcgttatggc catggcagcg atcggactta
     6541 ataccaatct agtgacctta gtcaaaactg gtggtaaggc cattttgctg ggtgggattt
     6601 gctggctagc gatcacatca gttagcttag caatgcaggc agctttgggg agctggtaac
     6661 tgatgagaat agctggtgat acgctgcttt ataggaaaag caaagccctt gctgctccta
     6721 aaaaagcttg ttagagcagc tcacttagct gttaagtgtg gcttggtggg gtgtaagtag
     6781 gctctatcag ttagaaaagc catcagaaca aacgctatca ttaagctgaa gccggggaaa
     6841 ctcggctttt acgttatgca gaattgtcta catattgaat aggattatcc attttaaaaa
     6901 cgttttcatt tgatagaata caattatagc ttggttatta gggtaaacga gattgaactt
     6961 cttatctggt ttagcttaag taaaaaagca gttggaggaa gcatgaaacg taaattttta
     7021 attggtagtc atgggagaat ggccagtgga ttgaaaagct ctattgacat tttggctggt
     7081 agaggtcagg aattacaagt cattgacgct tatattgatg atagtgatta tactgagcag
     7141 gtattgacct ttatcgaaga tgtagcagct gacgagcagg cactgatttt tacagattta
     7201 ttaggtggca gtgttaatca aaaaatagta actgccctaa tggacagtgg caaggaaaat
     7261 atctttttga tttcaaatag taatcttgca gccttgctat cgttgatgtt tttaaagcca
     7321 gaagaagagc tgacaaaaga cgagattgta gcaacgatta acgattctca ggtgcagctg
     7381 gtggatctag ctccagcgac agccgcagaa gatgactttt ttaattgagg aggaaaaatg
     7441 aaatgattac acaaattcgt gttgacgaca gattgattca tggacaggtt gctgttgttt
     7501 ggaccaagga gcttaatgcc cctttgcttg tggtggctaa cgatgaggct gctaaaaatg
     7561 agattacaca aatgactcta aaaatggcag ttcctaatgg catgaaatta ttgattcgct
     7621 ctgttgagga ctctatcaag gttttcaatg atccacgcgc agtggataag cgtatttttg
     7681 tcattgtcag ctcgattaag gatgcttgcc agattgcaaa gcaggtgaag gacttagagg
     7741 ctgttaacgt tgcaaatgta gggcgctttg acaagtcaga cccagcaact aaggtcaaat
     7801 tggcttcaag cctattgtta aatccggctg aattagaagc agcaaaagag ctggttagcc
     7861 tgcctaacct agatgttttc aatcaggtac tgccatctaa tagcaaggtt agcctgagcc
     7921 agctcatcaa ataaagaaag gtgtaatgac tatgttagta ccagcaacaa tggcagcctt
     7981 agctgtattg atttgtttcg ggggaaatta tttaactggc caaagcatga tggaaagacc
     8041 gcttgtggtt ggtttggtga caggattgct cttaggagat atgaaggtcg gtatcttgat
     8101 gggagcgtca ctagaggcac ttttcctagg aaatgttaac attggtggtg tcattgcagc
     8161 agagcctgta acagcaacag ctatggcaac gacctttacc atcatttcac atattgatca
     8221 aaaagcagct atgacgctag ctgttccgat tggcatgcta gcagcctttg tggtcatgtt
     8281 tttgaaaaat gtttttatga atatctttgc gccaatggtt gataaggcag cagcggcaaa
     8341 ccatcagggc aagcttgtca tgctgcacta tggcacatgg attgtctatt atttgattat
     8401 tgcctctatt tcctttatcg gtatcctagt tggaagcgga cctgttaacg cctttgttga
     8461 gcatattcca caaaatctga tgaatgggct aagtgcagct ggtggtcttc ttccagcagt
     8521 cggatttgcc atgctgatga agctcttatg gacaaataag ctagcagttt tcttcctatt
     8581 aggctttgtg ttgacagctt atttgaagct accagcagta gctgtggctg cacttggtgc
     8641 agttatctgt gtgatcagct cgcagcgtga tttagagtta gatgctatta ctaagggagc
     8701 tatcagtaac caaagcagct ttgactctaa agaatcagaa gaggaggact tctttgcatg
     8761 agatctcaag acaatttaac taaagaagaa agaaaaatgc tacgctctgt tttctggcgt
     8821 tcatggacca tgaatgctag tcgtacagga gctacgcaat accacgctgt tggggttatc
     8881 tataccttgt tgcctgttat caatctcttt tataagacag ataaggataa ggcagacgct
     8941 cttgttcgtc acaccacttg gtttaatgcg accatgcata ttaataactt tatcatgggc
     9001 ttggttgcct caatggaaaa gaaaaacagt gaggatccaa cctttgacgc tagtgctatt
     9061 acagcggtca aggcttcctt gatgggacct atttctggtg ttggagattc ctttttctgg
     9121 ggtattttga gggtcattgc agctggtatt gggatttcac ttgctagcac aggctcagcg
     9181 atgggagcag tagtcttttt acttctctat aatattcctg cttttatcat tcattattat
     9241 agcctttatg gtggctattc tgttggtgct ggctttatta aaaagcttta tgagtctggt
     9301 ggtattaaga ttgtgaccaa gacctcaagc atgcttgggt caatgatggt tggctccatg
     9361 acagcttcaa atgtgaagtt taagaccatt ttaacagttg ctgcaaaggg agccaaggaa
     9421 gcagcctcta tccaaaatta tttggatcag ctctttattg gaattgtccc tcttttagta
     9481 accatgaccg ccttttggct tttgcgtaag aaggtgaaca ttaactggat tatgtttggc
     9541 attatgctat tgggtattgt tcttggtctt ttaggtattt gctaataatc tcctagcatc
     9601 aaggataggt aaggcaggga cttcttgctt tgcttatcct tttttgtagt gagggctgct
     9661 gaaatagcca cctgcttgct taaatggctt atggatttgt tagatagatt aagattttct
     9721 tagctttgag aaatgatttg gtataataga aggaaataag ggaaaaggct gcctatggaa
     9781 gaaagattta aaaagcgatt gcaggatgat atttcacatc atttttcaca ccaatcattg
     9841 attttgtcca ttttactgat tggactcttt ctcatttttt cattggcacc tcagcaaatt
     9901 gggctgtatc aagatttgaa ggctgttgaa catagctatc accagctgat tcggcaaaat
     9961 aaggcgcttt taacggagct caatcagcat attctgacca aatttgtgaa tcatcagctg
    10021 agctcttctg accttagcaa acaatattat cacctaagaa accgctcaca aagccaatca
    10081 gagctgctgg tttttgatgc taacagtcac atgctgtttg ctagtaatca gcatctggga
    10141 aatttttttc gcaatgctgt ctatatgaca gaagtcttaa aaaaagcaag gcaaaggagt
    10201 agcttcttga ggatcagtat ggataatgag gaggggcatt atttactgct gataaagcct
    10261 attaagatag atcatcaggt taagggctat tcgcttcttg tgatgaatgg taaggatttt
    10321 cttcagctat cacatcagat tgcttcagat tttgtgattg cagatcagtt tgacaatagc
    10381 tttgccttta ccaatcggac ctttatgacc tcaagtctga ataagcttga cagtcatttt
    10441 cttaagggct attttatctt tcacgagcat cgtgccttta tcctaagaaa ggtcgctctt
    10501 agtccttcta tcactcttta cagctaccgc cctttgattc cagtttctat tgcactcttg
    10561 ttttcattga tgtcctctgt catgatttat gctattttgt attggaagtc taaggctctg
    10621 gcgacgcaga ttgcttctag caattcagca gcgatcaatc agatgattct tgatatgcag
    10681 gccatctcaa ggcaggaaaa aaatgccatt gacctgcaaa gtcaagatga atttcaatac
    10741 ctgtcggttc agatcaatca gatgattagc cgattgcagg cacttcatca gaagacccta
    10801 gccttagaaa agcaaaatgt gagttttgaa aaacgcatgc tggaagccca atttaaccct
    10861 cattttctct ataatacact tgaaacaatt ttgattacaa gtcattatga cagtgacctc
    10921 acagaaaaaa ttgtccttca gctaaccagg ctgcttcgct atagcttaga cgaatcacag
    10981 gaggctgtgt gtctgggaga ggatttggct gtcttagaat cctatctgtt gattagccag
    11041 attaggtttg aagagctgcg ctacacgata gctgttgaac cagccctaga gaccctaagg
    11101 gttcccaaat tatttttatt gccattgatt gaaaatgcga tcaaatatgg tctgcgctat
    11161 cgccatgacc ttgtgattga gatcagcgtg agacagcttg ctgatggaat ttactttact
    11221 gtagcagata acggtcctgg aattagtcaa aaaaggcagg ccgatattaa agagctcttg
    11281 cattcagagg attcacatca tggcttggtc aattcttatc gtcgactcaa gcatcaattt
    11341 ataaaagttg aattgatctt ttgtcaaaga gatgagcgct ttttactaac ctatatggtt
    11401 aaggagtaac agatgtataa gctactaatt gttgaagatg agcatattat tcgcaaatgg
    11461 cttcgttatg cgattgatta tcatgcgctc aatatccttg ttatcggaga agctaaggac
    11521 ggtcagcagg gggctaagct gattgcagag gctaagccag atattgtttt gacagacatt
    11581 aacatgccga ttatgactgc ctttgagatg tttgaggcca caaaagagca gtcctatgct
    11641 aaaatcattt tgtctggcta tgctgatttc gctaatgcaa agtctgctat ccattatggt
    11701 gtgcttgagt ttttgaccaa gcccttggaa aggcaggcct tacatgattg cttgctaact
    11761 attatccaaa agctgcaaca gcagtctcaa gagcaggagc taagccagca gcaggattac
    11821 ctcaaactgc cacagcctaa tgaccaattg cctgatgttg tccaagaaat gctcagctgg
    11881 atccatgagc attaccagga taaaatcatg attggtcagt tggctcacga tctgggctat
    11941 agcgaaagtc acctctatca tttagctaaa aaatacctga aaatgacttt tagtgactat
    12001 atcaaccaat accgcctgaa tcgagcaatt caattgctga ttgctgagcc ggatgtgatg
    12061 gtttatcagc ttgcagaggc tgttggcatt tatgactacc gctattttga tcgtgtgttc
    12121 aaaaaatatt taggacaaac ggtcaaggat ttcagagaaa cggtattaca ccagagatca
    12181 gataggagtt cattgtgaca agaaaaaagc tgctattagc aatggcaata gtgatactag
    12241 gtgtgattgg ctctggcttg tatgctatct ggaggcatca agcaggacca gctcccagca
    12301 aaccaagaga attggttgtt ttgacaccca acagtcaaaa tatcctaaca ggtacgatcc
    12361 cagcctttga agaaaaatac ggcattaaaa tccgtctgat tcaaggaggc acaggccagc
    12421 tcattgatcg cttgcaaaag gacaaggacc agctccatgc agacatcttt tttgggggga
    12481 attacacaca atttgagagt cataaggagc tatttgagcc ttacctttca aagcatattg
    12541 gctttgtatt gcctgattac ctgctgcaaa gcgaggtcgc aaccccctat acgcttaatg
    12601 gaagtgttct cattgtgaat aatgaattgg caaaggacat ggttattacc agctatgagg
    12661 atttgctaaa gccagagcta aagggaaaga ttgcttttgc agaccccaac acctcctcta
    12721 gtgccttttc tcagctgacc aatattctct tagccaaggg gggctacact aaccccaagg
    12781 cttggagcta tatcaagcag ttgattcata gcatgaattc aatcaaatct gctagctcat
    12841 cagatgttta tcagtcagta gcagaaggaa agatgaccgt cggtcttacc tatgaggacc
    12901 cctgtgttaa ccttttaaag agtggtgcca acgtttctat tgtgtatcca aaggagggaa
    12961 cggttttttt accctcagca gttgccattg ttaagcaatc taaggccaag gctgatgcca
    13021 aattgtttat taattatatg ttgtctttag atgtgcagcg ggcctttggt caatcaacca
    13081 gtaataggcc aattcgaaag gacgctaagg ccagtcaaga catgaagcct ttagatgaca
    13141 ttatcacgct aaaggaagac tatgattata tcacaagaca taaaaaggat attttagaac
    13201 gatacaatca attgagaaag accactgact aaatggcttt gttatatgaa acagttcatg
    13261 ctgtgctgca cctgaatcgt tagctgcttt gtctagcttt ttgaggtcaa tctctgcttg
    13321 ggctgttttt tatgttacca taacccactg catttgttta gaaagtcaag cgagatctta
    13381 atagccagtt ataataggtc tttgagaggg agtctgagct tgcttgaggt ggcaagaaga
    13441 tctgttttga cgtcaaatgg ctgaattttt ggtaaaatga tagcatgaat gaactgataa
    13501 aacacaagct agagcttttg ccagatagtc ctggctgtta tttgcataag gataaggctg
    13561 gcactattat ttatgttggc aaggccaaaa atctgagaaa tcgcgtacgc tcttattttc
    13621 gaggaagcca tgataccaag acagagctgt tagtttctga aatagctgat tttgagttta
    13681 ttgtcacagg atcaaataca gaagcactct tattggaaat caatttgatt caagagaaca
    13741 tgcccaagta caatatcaag ctaaaggacg acaagtctta tccctttatc aagatcacta
    13801 acgagccatt tccaagacta ttaatcacac gtcagattaa aaaaaatgac ggcctgtatt
    13861 ttggtcccta cccagatgct tacactgcca ctgaggttaa aaagctgcta gaccgtattt
    13921 ttccctttaa aaaatgcaaa aaccctgtta acaaggtctg cttttactat catttagggc
    13981 aatgtcaggc tcacacgatt tgccatacag acaaggctta ttgggacagc ttggttgctg
    14041 atgtcaagca gtttttaaac ggtaaggacg acaagatcat tgatgatttg cgctccaaga
    14101 tgcttgaagc ttcgcacaat caagaatttg aacgggcagc tgaatatcgt gatttgattt
    14161 caggtattgc caccatgcga accaagcaaa gggtgatgag taaggacttg caggataggg
    14221 atatttttgg ctattttgtt gataagggct ggatgtgtgt gcaggtcttt tttgtccgtc
    14281 agggtaagct cattcagcga gatgtgaata tgtttcctta ttacaacgaa gctgaagagg
    14341 attttttgac ctatgtcggg caattttata gcgaccaacg gcatttgatc cctaaggagg
    14401 tctttattcc agagacgatt gatgagacct tggttgcagc cattgttcca gcaaggattg
    14461 tcaagccgca gcgaggggaa aaaaagcagc tggtcgcctt agcaactaag aatgctcggg
    14521 ttagccttca gcaaaaattt gatttgctgg aaaaggattt aagaaaaaca agtggtgcta
    14581 ttgagcatct tggtcagctg ttaggcattg aaaagcctgt tcgtattgag gcctttgaca
    14641 attcaaacat tcagggcaca agtccggtag ctgcgatggt ggtttttgtc gatgggaagc
    14701 ccagcaagaa ggactatcgc aaatttaaaa tcaaaacagt gattggtcca gatgattatg
    14761 cgagcatgag agaggtgatt tatcgtcgtt atagccgcgt gaagcatgaa gggctacagg
    14821 cacctgattt gattattgtt gatggtgggc agggtcaggt caaggctgct cgtgatgtga
    14881 ttgagcacca gctaggcctt agcattccag tagctggtct gcaaaaaaat gacaagcacc
    14941 agacccatga attgcttttt ggtaacccct tggcagtggt tgagctgccg agaaattcag
    15001 aagagttttt tctgctgcat cgtatacaag atgaggttca tcgctttgcc attacctttc
    15061 acaggcaggt caggagtaaa aatgcctttt catcaaagct agatcacatt gcaggcttag
    15121 ggccaaaacg caaacagcta ctactcaagc gatttaaaag catgactgct cttgaacagg
    15181 ctagtcttga agaaattcag cagctaggga ttccaaaaac agtcgctgag gcactgtttg
    15241 atcaccttac ctcaaaaagt gaggtctgaa ttggccttgt caggagctca agcagtctga
    15301 attttcttga caaaagtgaa aaaatagctg aaaccagttt caaaaaatga tagaatgata
    15361 ctacaacata aaagaattag ataggaagca tttgcagtga aatttctcga attaaacaaa
    15421 aaacgccatg ctattaaacg gtttaacgat aagcccgttg attataatga cttgcgaaca
    15481 gctattgagg ttgccactct ggcaccaagt gctaacaata ttcagccttg gaaatttgtc
    15541 attgttgagg aaaaaaaggc agagctggca aaggatctgc cgttggctaa taagactcag
    15601 gtagagcagg ctcagtatgt tattgccctg ttttctgata ccgacctcat tcagcgctct
    15661 cgtaagattg cccgcattgg ggtcaagtcc ttgcctgata acttgattgg ttattacatg
    15721 gagaccctgc cgccacgttt tgctaccttt actgagaccc aaaaaggcga atatctggcc
    15781 attaatgctg gcttggtggc gatgaatttg gtccttgcct taacggatca gaaaatggcc
    15841 tcaaatatta ttttaggctt taataaaaag ctaactaatg agattttaga tattgatcca
    15901 cgctttcgtc ctgaattatt gataactgtg gggtatagcg atgacaagcc agagcctagc
    15961 tatcgcctac cagtagacga aatcattgaa agacgctaag atacacaact actcgtccag
    16021 ctagcctata agtttttgga tttaggagga tagcgaggca acacataaag gagaaaaaga
    16081 tgacaacaat tgattttaaa gcagaggttg ataagcgcaa ggaagctatg ctagaggatc
    16141 tatcaaacct attaagcatt aattccgagc gagacgatgc taaggcagat gccaagcacc
    16201 catttggtcc tggtccggtt aaggccttgg agttctttct tgccatggca gagcgtgatg
    16261 gttaccaaac gcgtaatatt gataactatg ctggtgattt tgaatttggt cagggagatg
    16321 aggttttagg gatttttgcc catttagacg tggtacctgc tggtagtggc tgggagacag
    16381 acccttataa gccggtgatt aaggataatc gtatctatgc gcgtggttca tctgatgata
    16441 aggggccaac catggcttgc tattatgccc tgaaaatcat caaggaatta ggcttgccag
    16501 tttctaaaag ggttcgcttc attgttggga ctgatgagga gtcaggctgg ggtgatatgg
    16561 actattattt tgctcacaat ggcttgaaga accctgattt tggtttttca ccagatgctg
    16621 aatttcccat tatcaatggt gagaaaggaa acattacaga ataccttcat tttgttggtc
    16681 aaaatgctgg agcttttgtc cttcatcgct tccaaggcgg tttacgtgaa aatatggttc
    16741 ctgaatcagc gacagctctg atcagctcac cgcatgagct taatgttatc gaagcttctt
    16801 tggagcaatt cttatctgag cacgcagtga caggatctgt caaagaggct gatgggctat
    16861 tggaagtgac cattattggg aaatctgctc atggctctac accagaggct ggtgttaacg
    16921 gtgcaaccct gctggctaaa ttcttaaatc aatttagctt tgatggcgca gccaaggctt
    16981 atttgcatat tgcaggtgag gtgcttcatg aggatttcac agcagaaaag cttggcttgg
    17041 cttatacaga tgacaaaatg ggtgccctta gcatgaatgc aggtgtcttt agctttgcta
    17101 aggattcaga tgacaatacc attgccttga atttccgtta tccaaaggga accaatgcag
    17161 cagtgctaaa ggcagggctt gagcaattac caggcttgac taaggttacc ttatctgagc
    17221 atgaacacac ccctcactat gtgccaatgg acgatgagct ggtctcaacc ctcctatccg
    17281 tctatgaaaa gcaaacagga ctcaagggct acgagcaggt tatcggtggt ggcacctttg
    17341 gacgcttgct tgagcgtggt gttgcctttg gtgcgatgtt cccaggtgat gaaaacacaa
    17401 tgcatcaggc caatgaatac atgccattag acaatattta ccgatcagct gccatttacg
    17461 ccgaagctat ttatgaattg atcaaataag agattgaaca agctctctgt ctaagatgag
    17521 ccttgctaat attaacgaat aaaagcctta tgaagttagt cgtttaatga gacttcataa
    17581 ggctttttgt ttggcgtcaa gccattattt acaaagagaa atgccacagt ggatcatctt
    17641 ttgaaaagtc cttgtaaaaa cagacgtaaa actagtttta gaggagacat tgataggcag
    17701 tcatgcttat caagagatct tgtctagcag ttatggcaaa aagatcagtg aactattatt
    17761 ttccaaggca gaactgactg aacaattgag taattaattc atcaggtgcg gcatcgcctg
    17821 tgatttctcc taggatttcc caagctctgg tcaaatcaat ctgtaagaga tcaaccggca
    17881 ttcctaaagc aagtccttca ttgacagcct ctaagctttg tactgcctgc tcaatcaagg
    17941 aaatatgacg agcattggat aggtaagtcg catcttgctc tattagccca gtatgatcaa
    18001 agaaaatctg attgatccgg tcttcgatca ggtcaatgtt ttggttttgc aaaactgata
    18061 ttgggatcgc ctcttctgga agctggtctt tttcaatgac ctgctccaga tcggttttat
    18121 tgaggagaat aatgcgattg ctatcctgac taagggctag cagagccttg tcctgttcgg
    18181 tcagcttttc cgaagcattg agaactaaaa ggaccagatc agcctcctgt agggcttttt
    18241 tagaccgctc aacaccaatt tgctctacta aatcatctgt ttctctaatt ccagcagtat
    18301 caactagctt tagaggaatt cccttgatat tgacatattc ttcaatgaca tcacgagttg
    18361 ttcctgcaat atcagtgaca atggccttat cctcacgtaa caaggtattg agcagactag
    18421 actttcctac attcggtcgg ccgataatag ctgttgacaa gccctcacgt aggatcttcc
    18481 cgcgcttggc agtacgtagg agctgctcta aaagtgtttg aaattctcgc gttttgtcac
    18541 gcaaaagagc agtggtcatt tcttcgacat catcatattc ggggtagtcg atattaacct
    18601 caacctgggc taaggtattt aggatttctt gacgtgtgtc gctgatgagc tgtgataggg
    18661 agccgtctag ctgcttgata gcaatagaca tggccttatc agtctttgca cgaatcagat
    18721 ccatgactgc ctcagcctgt gttaaatcaa tacggccatt taaaaaagca cgctttgtaa
    18781 attcgccggg ctctgccatt cgagctccct gtttaatgag gagctgtaaa atgtcatttg
    18841 tcaccgcaat accgccatgg gtattgattt caatcacgtc ctctctggta aaggtttttg
    18901 gcgccagcat gactgatacc atgacctcat caatcacttc acctgtgctt ggcttgataa
    18961 tatgaccata gttaagggta tgtgaggcga ctgttgttag atcttttcct ttaaagatcg
    19021 atttagcaat gtccagagcc ttggtaccag acaagcgaac aatgccaata gctccttcac
    19081 ctaacggagt tgaaatggct gcaattgtat caaattcttt agttatactc atgccttcta
    19141 ttgtagaaca agtcagcata gaaagcaagg tattgcatta gctgctcgtt gtcgtcattc
    19201 ttgtctagtg gcaaagcctc aaaagcagtt gtaaacagct aaagctatga ttaaaaagcc
    19261 ttgtatggta agtacaggat aaagccaaaa agctgatgag ttttagataa acatacaggc
    19321 tcgaaaagcc ctattaaacc gacagcaaca atcctcacac agtatagttg acttaactac
    19381 ctgatgtcat ttctggctgt ttttataatg acaatggcaa tatcggttat tttgactatg
    19441 ctgggtgctt gtatcctagt ggactgactg acaatcaggg cttctttttc aaccacgaaa
    19501 acattaaaaa agtctggttt ggaggctata ttgacgatag tgaaagagaa gctcaagact
    19561 tttttaaaaa agaggcaggc tatattaaat atcctaaact tagtatagat aatagcacta
    19621 gatagcatta atttaagtat ataacgttat gattatggtt ggattagttc attatacact
    19681 agcaataagg tagattattt tgttataata aaatatatac aattattaga gagttagaaa
    19741 gagttatatg gtagtattac aaaataatag tagcacagct agtgagcgag cgacagcttt
    19801 ggcaagagga gtccaggccc tctctagtgc tggtgcggtg agcaaagata tgaagacgac
    19861 cgttactgga aatcgtagtg atgccagctc tgccattgat ttatcgcaca acgtttcagc
    19921 gcaggtagtt gggatcatcg cttctatgtc gcaacacatt cagagtgtct ctgcctcttt
    19981 tcaagcgatg gatcttcagc ttggaaaaga gttagggcgt ttagaaaaca ggcggaggtt
    20041 tagtctcaat gacccaaaat gagctcatgt accagaagga gagattggat aaacgcttgg
    20101 aaaccatagc ccaagagctt aagcgtaatg aacagcgctt tgaagactat gaggaactat
    20161 ctaacctagc ggcacaactg ttaacagcag ctgcaaccac ctttcgttca tcatcagata
    20221 gtcatctctt tgaaggggct ttggcagaag aatgttattt gaaaaggaaa acacaagcgt
    20281 ccttggaaca aagtcatgag gagctcttag gagagcagcg tcgtttgtac caagaagagg
    20341 aagccctcac ccgacaatta aagctagtca aaggaaagga gagagctaat gagcattgac
    20401 atgtatctgg ggtcatcgga ccagcaagct agtagcgttg gtaaggtctt gcagcagcgg
    20461 ataacagctt ataagtcttt gcaaagagct ttggagcaat tggtgtcttc tagtcctgac
    20521 ttatcagggc atacctatgc ttctgctaaa aggtacagcg agcaggtatt gatccctttg
    20581 atgaggggct gtatcctgct agatgaagcc atcaaggaag cctgtgcagc atttcctaat
    20641 gactaccgtc gtcaggttga tagtgtggat ttgaaggaga gtgagctggt ggatcagatc
    20701 agccgctcag accgcatcat aggtcgttac gttgagttga ttgatctgga gtatcggcag
    20761 gagctgccga attactctta tattactaat ctcaagagcg gagcgagtaa ccagcgtcaa
    20821 gtcaagagaa aattagaaga gaagctcctt aagctgcgag agtttgatag caattcccgt
    20881 cacctctttt cgtctatcgc agccttagcc gaggcagtca atataggtat cagacaaacc
    20941 aagacctctt ggaatgggac aagtcagacg ttcactcttc ccagggctct tgacttagag
    21001 tggaccaagg tagtagaaaa gaggtggacg caaagggagg aaaaagcctc gaagctgaag
    21061 ctacagcagg cagcagaaaa actttcgaga gaaaccggga ttaagtacga agatgcctat
    21121 cgttttgtga tggacggtgt tctgtcagat gaaaataaga acaaaatcaa gagtgtaaag
    21181 aaactagtta agtatacaaa gggtgggctg tatatcgttt cctcaggaag gtattattgg
    21241 aaacattcag gtaaacatta ttggaaaaat acaccaaaca aaacatggaa tatttggaaa
    21301 gcatctaaaa acgatcccaa ttttgacaaa ggagggatca aaggtaaaca tttttctaaa
    21361 aaaggagccc gttacacaga cttacctggt atcaagcaat tgaagaagag tgaaacagta
    21421 caatccctca tttcaaaaat ttcaaaagat aatcaaggga agctcaccaa agttggtaaa
    21481 gggttaaaga aagttgataa agagctaagc aacatatcgt caaaactcaa gtcatatgag
    21541 catggacgcc taaatagaga cttgaaaatg atgaaggaga ataacctggg taaaagtctc
    21601 ggtaagtttg ggaaagttgg aaaagctgca agcaaggtgc tcaagtttgc aggaaaaggt
    21661 ctcaaagttg cgggttgggt aggtgctgct ataaatgtta aggactcggt tgaaacttac
    21721 aagaaaaaag gctatagcaa tgagcaaact gctgctttaa cagcccgtaa ggtagctgtt
    21781 gatactgcaa caactgttgt cggaagcaat attgggcgtg taacaggtgc agttattggt
    21841 caagcagtta tacctattcc aggtgtaggt gctgctatcg gttctgttgc aggaagtatt
    21901 ttaggagcta tggcaggtag ttggattggt agtacaatta atgacaattt agataagaac
    21961 gtaaaaccta aacaatcagg aaggagttta gcatggtaat gttaatgaga acactgttat
    22021 ttccagttga taacggactt gattcaggat tgactggtga tggttatgca gctgagtatg
    22081 atttgtggac tggaaaggtc acgtggcgac aacttggtga tggaaaaata aaaaggcaac
    22141 aaaaggtagc agctataatt aatctcattg cagctgcaat atctccactt gtcatcatgt
    22201 ctatcatttt tacggcaaaa agtctgaagc tttttgatgt agatactagt acaacaattt
    22261 atcgatatgc tcctctgatg gtaggcttgg tctttttctt ctcgtttgaa ttattgatgc
    22321 tggctattag acgtctgtat ccattagcca aagaggagcc aagtttaaag cgtcaacatg
    22381 ggtattttaa gaccatgtat gacaatacta tacgtgagaa tgatggtgtt tttaataatt
    22441 tatcagtacc ttttataggg ctttatgtag ctttcttgat tgccttttcg gttattccaa
    22501 ttttttactc tcaatatctg cagcaaaatt ctttttggtc ctatttagga aatttagtag
    22561 gaagtagcat tcttatttcc ttagtcccca attttttatg gaatgtctta gtgaaacaat
    22621 tgatttacat caagcttatt cgcaaaacga aagaaaaaat cttaaagaat gaaacctaaa
    22681 caatcaggaa ggagtttagc atggtaatgt taatgagaac cttgttattt cccatagata
    22741 atggtatgga taataactta attggagacg gcttatcagc tgagtatgac ctatggactg
    22801 gaaaagttac gtggcgtcag cccagtgatg ataagattag aacccaacaa aaggtagcat
    22861 ttgtacttaa tcttatagct ggtagtttat ctccattagc tatattttta tttgttatta
    22921 ttgttagacg cttaggcgtt tttagtggcg atactaattc aatgattttc aagtgggcac
    22981 cgctaatagt tggatttatc ctttttatat cgtttgaatt attgatgttg gcgcttagaa
    23041 gtagatatac gatattagag aaagagcccg atttagatcg tcaactatac tattatcgta
    23101 caatgtatga taatactata catgacaatt caggtgtttt taacaattta tcagtacctt
    23161 atgtaggtct atacattact ttatttctaa tttttttaat cattccactt tgttatcatt
    23221 tttacttgca cccatcttca tttggggatt atctcgctgc attatctgta acaagtttgt
    23281 tgatttcctt atttcccaat tttttatgga atggtgtctt gaagcacgtt atatatgtca
    23341 aacttattcg ccaaacaaaa gaaagaattt taaagaatga aacctaaaca atcaggaagg
    23401 agcttagcat ggtaatgtta atgagaacgc tgttattccc agttgataat ggcatgggaa
    23461 cgggcttgac cggtgatggt tatgcggctg agtatgatct atggactgga aaggtcacgt
    23521 ggcgacaagc caccaaacaa acaattgaaa agcaacaagc actaacgtct aaccttttga
    23581 ttattgcctc atgcttatca ccagttactg ttgcaggaat gatactgttg agtagaagtt
    23641 tccctatttt cgaggaagac ttatcagaga aaattgatac ttatgctcca attattcttg
    23701 gtgttgtgtt atttcttgct tttgagacgt taatgcttgc tatcagaggt cgtgatccat
    23761 tagcggagaa ggaaccagat ttaaagcggc agcatgacta ttttgaaaag atgtttgatt
    23821 ttgctattcg tagaaatttg tcgtcagata atttaaaaac tccttatata gctacttatt
    23881 ttgcttttgg tatttcttta ctctgtattc catttagcta ttatgtttat ctgaatccgg
    23941 agcaattccc taatttggat tatggtcatt tatcaatcct gcttgtaaca agtattctta
    24001 tttccctagt tcccaacttt ttatggaatg ttctattaaa gcacattatc tatatcaagc
    24061 ttattcgcaa aacgaaagga caataaaaca ttatgaacaa accagaacac attttaccga
    24121 ttggtactat agtgctgacg gagacaggag aaattccttt gatgattgtg agtcgtgcct
    24181 ctctttttga tgataatgga gaaatcggct attttgatta tgctgcagtt ccttatccag
    24241 aaggcatagg aaatgataat gagtaccttt tcttcaacca tgaggatatt gctgatgtca
    24301 tctattttgg gtatgtcaat tccaatgaac agctttttgc agaagcctac gatgatttgg
    24361 tgaaaacatc aggttatcgt aaattaagct tagatcacca tcaatagaaa aaggacatga
    24421 agattatcta gaaaaagaaa agaactaatg agcattgaca tgtatctggg gtcatcgaac
    24481 cagcaggcta atgatgtatg gccaatattt tgagaggatc ggcctgctcc tcttttttgt
    24541 atgttcaaag ctataaaaag cttacttttt gaggtataaa gcttcgacaa tcaagagtat
    24601 ttgctctggt ggctttaatg atcttgctta tagcttctgg tcagattgtt ttagcctgct
    24661 tgtgctgtct gatccagatt tgactgaggc tttgatgaca gtcgtgaagg cgggtttaag
    24721 aatggcatgt ctaatgtcaa tttacaatag agaaggaaaa ttgatcaaac agtgtgagat
    24781 attattaaca agtttgcgct ttcatggtat aataaagtgc taggaagcat tttattataa
    24841 gataaggggg aatcatggaa gcactgaaaa agattgccgg tgtgactgct gcgcaatatg
    24901 taacagatgg aatgaccatt ggattaggaa caggatcaac agcttattac tttgttgaag
    24961 aaattggtcg tcgcatcaag gaagagggac tacaggttgt tggtgtgaca acctcaagtg
    25021 taacaaccaa gcaagcagag ggcctaggta ttcccttaac atcaattgat gatattgact
    25081 gcattgacct gactgttgat ggtgctgatg aggtggataa ggcctttaac ggtattaagg
    25141 gtggtggagc agctctattg atggagaaaa ttgttgcaac accaaccaag gaatacatct
    25201 gggttgttga tgaatcaaag ctggtggatc atttaggtgc tttcaagctc cctgttgagg
    25261 tcgttcaata cggtgctgat aggctatttc gagtctttga aagggctggc tataagccct
    25321 cttttcgcat gaagggggat aagcgtctca taacggatat gcagaacttt atcattgatc
    25381 ttaaccttgg ctgtatcgaa aatccttgtg agtttgggcg tctgctggat caaactgttg
    25441 gtgttgtcga gcatggcctt ttcaatggta tggttgataa ggtcattgtt gctggtcagg
    25501 ctggtgtaac ggtccttgaa gctaatcagt caacctaatt cctagctcaa tcatgtttta
    25561 cattatttta taggttttgg ggagccaacc gtaacctccc ctagattgga gacttatgtc
    25621 aaaatttaat cgtattcact tagtcgttct agattctgtt ggtattggtg cagcaccaga
    25681 tgccgacaaa ttctttaatg ctggtgtagc tgatacagat tctgacaccc tcggtcatat
    25741 ttcagagaca gctggtctgg ctgttccaaa tatggcaaaa attggacttg gtcatattcc
    25801 tcgtcctgtc cccctaaaga cagttccagc tgaggctgat cctactggct atgtcaccaa
    25861 attagaagag gtatctcttg gtaaggatac catgacaggt cactgggaaa ttatgggctt
    25921 aaacattact gagccatttg ataccttctg ggatggcttt ccagaggaga ttatccaaaa
    25981 aatcgaagct ttttcaggcc gtaaggtcat tcgtgaagcc aataagcctt actcagggac
    26041 aaaggtgatt gatgattttg gtccccgtca aatggaaact ggtgagctga ttgtttatac
    26101 ctctgccgac cctgtattgc aaattgcagc acatgaggag gtgattcctg ttgaggagct
    26161 ttaccggatt tgtgagtatg cgcgttccat tacccttgag cgtcctgctc ttttaggtcg
    26221 tattattgcc cgtccgtata taggagagcc aggcagcttc actcgcacag ctaatcgtcg
    26281 tgattatgca gtctcaccgt tccaagacac tgtcttaaat aagctggctg acgctgggat
    26341 ttctacttat gctgttggga aaatcaatga catctttaat ggctcaggga ttaccaacga
    26401 tatggggcac aataagtcta acagtcatgg gattgatacc ctgatcaaaa gcttgcagtt
    26461 gccagcattt acaaaaggtc tttcttttac taacttggtt gattttgatg ctagctttgg
    26521 tcaccgtcgt gatccagagg gctatcgtga ctgtttgcat gaatttgatc gtcgcctgcc
    26581 agagatcatt gccaacatga aggacgatga tctgctcttg attacagctg atcatggcaa
    26641 tgacccaacc tatgctggaa ctgaccacac acgtgagtat attccattgc ttgcttactc
    26701 agcctcctgc actggagcag gtgtgattcc acagggacat tttgctgata tttcagcgac
    26761 tattgccgaa aacttcggtg tggacactgc tatgattgga acatcattct tagctgactt
    26821 ggtataggag taagcaaata tcatttgata ggccaaggag cttggcgtat caaattgaaa
    26881 accagcgctg tggttaggtc tattaatagg cttgtggcag gttgtctagt tctgatgatc
    26941 ggtgtgatat tagttgattt attggacttt gctacagcaa aaagctcaag agaagtatgc
    27001 tttatagtaa aaaataaata agataaaggg agaaataaga tgacattact tgaaaaaatt
    27061 cgtgaaacac aggctttcct agaaagcaag ggcattgata agcctgaatt tggtctcatt
    27121 ttaggctctg gtctaggtga gcttgccaat gaggttgagc aggcgattgt gattgattat
    27181 gctgatattc caaactgggg caaatcaaca gttgttggtc atgctggaaa attagtttat
    27241 ggtgagctgg ctggtcgtaa agtattggca cttcaagggc gctttcattt ctatgaaggt
    27301 aatccaatgg aggttgtgac cttcccggta cgtgtgatga aggctctggg ctgccatagc
    27361 ttgctggtga caaatgcagc aggcggtatc ggctatggtc ctgggacgct tatgctaatc
    27421 aatgaccata ttaatatgac aggaacaaac ccgctcattg gtgaaaacct agatgaattt
    27481 ggcccacgct tcccagatat gtctgatgcc tatacagcag cttatcgtga gacagctcgc
    27541 tcagtagcag aaaaactagg cttagacctg caagagggtg tttaccttgg ctgttcagga
    27601 ccaacctatg aaacaccagc tgagattcgt gcctttaagg ttatgggagc agatgctgtt
    27661 ggtatgtcaa ctgttccaga ggttattatc gctgcccact caggcttgaa ggtgcttgga
    27721 atttcagcga ttacaaactt tgcagcgggc ttccaatcag agcttaacca tgaagaggtt
    27781 gtagaggtaa ctgagcgtat caaggaaaac tttaaaggct tggttaaggc tattttggca
    27841 gagctttaag gcttgctctt agactagcag taaccatgag cgactgctag tactttgatc
    27901 gataagacga ggaaaaataa ggattgggac attagagtga tgactgatat ggaacatacg
    27961 ataagtattc ttttagaagt ttatgcttat agtcatgcct acaaaattgc aagaactctg
    28021 cctgattttt cccccaaggt actttatttg cttgagcttt taaaggaaag aagagagctt
    28081 aacgttgctt atgcctttca acatagggcg gaaaataggc ttattgagga tagacatcag
    28141 gttaagcttt tgttaaatga agctcaagag gaggagcaga ctgcaaatta cctgcttgat
    28201 ttggcagcta aggtcaaaaa cggtgagatt attgattttg taaggtcagt atcgcctgtc
    28261 ttgtatcgtc tctttttgcg gctgcttgag caggctgtcc cagatgttca aagctatatt
    28321 attgatacca agaatgatca atatgacact tggaatttta aggcgatgga aaaagccgat
    28381 aatgacctct ttaggagcta tctggcacaa agacagccac gtcatgtgac gacacgcagc
    28441 ttggctgatt tacttgtttt atcagagctt ccagctgata ttaaaagact agtggtagtc
    28501 ttaaggcagt ttgaaaaatc agtccgcaat cccctagcac atttgatcaa accctttgat
    28561 gaggaggagc tatatcggac aactcatttt tcctctcaag cctttctaga tggtttgatt
    28621 cgcttagcag ttttttctgg tgttaactat atcaaagagc ccttctattt tgatgtcgtt
    28681 aatgctgtca ttgaaaagga gctgttagac agcgccaagc cttagctatt tgaaagatta
    28741 gcaataataa aaaacctgaa cgatctgaac gaggcttctc taagctagct atgactagtc
    28801 agcttagagc cttagaacag gtctttcagg ttttttatgt ttagctagtg tggttaatta
    28861 atgattgaag ctaatttctt ctagcaggta gtcaataaat cgctctccca tttttgagag
    28921 gttagccttt tcgtgcttga taaagacaat ctcaatcaca tcagggacat ctaagggaat
    28981 agcgacaatc tggtctccat ttagatttgt gtttaaaata ccgctggcaa cggtgtagcc
    29041 atttaagcca atcatgagat taaatagggt agctcggtca ctcaccacaa tagacttact
    29101 gtgagggata tgtgccatca tctcctctga gaaataaaag gaattgtgaa tcccctgatc
    29161 atagcttaga taaggaaaat caaggagatc atcaatggtt aagctggttt tatttgccag
    29221 aggattggac ttgctgataa agatatgcgg tgtggtttta aatagggtgg aaacggtcaa
    29281 atgattttcc tcaaacagct tggtaaggac gtctcggttg tagtcattga taaacaaaac
    29341 gccgatttct gagcgaaaat ttttcacatc gtcaatgatt tcccaggttc ttgtttctcg
    29401 caagaaaagc tcgtactggg tcatatcagc ccgctttaat aaagagacaa aagcattgac
    29461 aacaaaggcg taatgctgag aggaaacact aaagagctca cgactagtat tgtgattttt
    29521 atagcgatcc tctagcagtg ctgtttgttc aataatttgt ctggcataag atagaaactc
    29581 aaccccgtcc ttggttaagg taatgccctt gggattacga atgaaaatag taatgcccat
    29641 ctcctgctct aattccttga cagcattaga cagactgggc tgcgtgataa ataattgctt
    29701 agcggcttcg ttcatggaac cgcattcaac aatctttata atgtattgta gttgttggat
    29761 tctcatactg acagtctatc ttaaatagta caaagaatca agtgccttta ttagagctta
    29821 agacaaggtt tcacaagcgg tagcctagct tgtgcggtga agctagcttg atgctagtgt
    29881 tgtacccagg taaaaaagag ctggcaaata ggcagtttta tcgcttttta ccgcttattt
    29941 ttggcatgcc tgtgttttga taaacggctg gtcttgatcg gtaaaaagta atcgtgataa
    30001 tgtcagataa tacctatttt tccattgctc ttttaatttt cttgtgttat attaataata
    30061 ttgatatatt taatgttttg agataaaggg tggtgatggt gtaatatgac tggacaaagt
    30121 agtcatcagg tattaattca aaagctgttg gtcagcactc actatttgac attatttaga
    30181 gatgagctga agctagttga gaggacacca tctattttgg gaagtgagtt tcctgtctct
    30241 cttgttcaaa cggaattagg tgatattatc accttggtgg ataccttaaa taagcagcag
    30301 cgcttgattg agtcgacctt ttggtatgag gagtcagcct ttaagctcat gaacaaggcc
    30361 ttagatattg ttgataattg gataaagggg atagatggct taattaagct ctgccagtcc
    30421 aaggaggtct ttcaggccat tgttggtgat aaaagaacac gtgtttttgg tgttttgatt
    30481 gatgtttttt cttccctaaa aattagcacc atgtcattga aggaatttgc agctccggct
    30541 gctctttgcc attagattaa gctgggctaa gcttggatag tggctggtta agcctgcaag
    30601 ttgcccctct catgacaagt ctaggcttta tttagggtga gcagtgtgcc aagggtgtat
    30661 taagtgctgg ttgctttgaa gcttcgcctt gctaggttag ctgtgagtga tgtcacgata
    30721 actgcgcgaa acagttattt ctgaattata atacaggtta aagtaggtac ttttaatgtt
    30781 tttcctattg taaaatctat acaaaatagg atatattttt gaaatagctg aacattaacg
    30841 tacagcaagc tttattttct tgctaaaaat cttttttata cctttgtcgt gtgagtaatg
    30901 tcaaaaccct ttgacaaggg ctgtcaaaaa agctataatg attgagataa gttaccttta
    30961 agtgagtcca gagaggcgag caaggtacac aggataagat gagagggttt gctctcttga
    31021 ttttcgtgta gcctcgcttc tttggaagtg aggcttttat ggtgtgactt tcagttggtc
    31081 tcgtggtaat gattcataag accaataaac cgctcgttag acgggtgggc atgatttgtt
    31141 tgggagtacc ccaagctgca tagaaaggat aggttatgcg agaagaacgc cctattattg
    31201 ccttagattt tccttccttt gaggaggtca agtcatttct gtcgctgttt ccagctgatg
    31261 agaggctata cgttaagatt ggtatggaac tgtattatgc tgaaggacca gatattgtcc
    31321 gttatgtcaa gtccttaggt cacagtgttt ttctggattt gaagctgcat gatattccaa
    31381 atacagtcaa atcaacgatg gcagtcctat caaggcttgg tatagacatg acgactgtgc
    31441 aggctgctgg aggtgtagag atgcttagag cagcgcgtga gggcttgggg cagggtccga
    31501 ttctcattgc ggtgacacag ctaacatcaa ctagcgaaga gcaaatgcgt gaggatcaaa
    31561 acattcaatc cacgctgtta gcatctgtgc ttcactatgc caagcgtacc gctcaggcta
    31621 agctagatgg cgtggtttgc tcagcccatg aggtcaaggc cattaagtca gaagtaccag
    31681 caggctttgt gtgtttgaca cctgggattc gcccgacagg tgctgacatc ggagatcaaa
    31741 agcgggtgat gacacctcat caagctagag ctatcggaag tgactatatt gttcttggtc
    31801 gtccgatcac tcaggctaca gaccctgtca aggcttatca ccagattaag gcagagtgga
    31861 accgttagca gcaggatcat catgacacat atagctggac tatgacacca aggaaaagag
    31921 gagaaaaatg acactagcag cacaaattgc aacagattta cttgagatta aggccgttta
    31981 cctaagacca aaggagccct ttacttgggc gtcaggcatt acatcaccga tttatacgga
    32041 caatcggatc accctttctt atccaaaaac cagaagcttg attgaaaatg gctttgtgga
    32101 gacgattaag gcagtatttc cagaggttga ggtgattgct ggcacagcaa ctgctggtat
    32161 tccacatggt gctatcgttg cagataagat ggacctgcct tttgcctata tccgcagcaa
    32221 gccaaaggat catggagcag gcaaccaaat agaagggcat gtgcgctgcg ggcaaaaaat
    32281 ggtgattatc gaggatttga tttcaacagg tggatcagtt ctggaggcgg cagcggcagc
    32341 tagtcgcgaa ggtgctgatg tactaggagt ggtggcaatt tttacctatg aattgccagt
    32401 agcaagcatc aattttgaaa aggcagggct ttccttggtg accttgtcta attattcaga
    32461 cctcattaag gtcgctaagg ccaagggcta tattgatgct gatggcttgg ccctgttaaa
    32521 aagatttaag gaggatcaaa agcattggca gcatgagagt taaacagtgc tgaaaagctg
    32581 ctgacatgct gactatgtct taaggagaga aaaaatgact tacaaagatt tacttgagat
    32641 aggtgagacc agttattatc agacggatcg cttgacttac tacaaaaatc ctgtggtatc
    32701 tgagcgctat tttgataatt accttagcta tcgtagcatg ccttctttgg ctgatttgaa
    32761 aaaggacttg gcctatgtgg caaaagagca gcaggattat cctagtcact acgcctttct
    32821 cttttttgct gaaaatgaag agctaagtac agacatgcga gcttatttga cagatcatca
    32881 ctttagcctt gaaaagcacc tgatctttac caatgagctg gcaaagcttc acctaaagga
    32941 gcgtgatata tcaccagtca ctattgaaca gctctcagaa acaagctttt ctgcctatct
    33001 ggcttacaaa tatcaggcta atttggctta tggtgaaacc tatgccaatc aatgcaaggc
    33061 tgataatgaa gccaatctat tgacaaacgg ctcaaccatt tatttagcca tcaaggaagg
    33121 gaagattatc ggagatatta cggcttggga atgtggcgac tatattgaaa tggacgattt
    33181 cagtgtagat gaggcctatc gtggtcgtgg tatcggtaca gccttacagc gtaaggccag
    33241 tcaaggctat aagaaggtca ttctcatctc agaagaagct aatcgcgcca tgtatgagca
    33301 ccaaggctat caggaggttg cttactactg gacagcgcta aaaacatcga ctagataagt
    33361 gataaagaaa cagattatag gattgaaggt gtaggctctt atgagtatga ctcttcaatc
    33421 ctttttttct gagcgcattt gctaatcata cctaatgaat aagtcgtagc ctgtctagtg
    33481 gctcatttta atggcgtctt gctctgtttt atgattaaat atagagaaaa agctattgtt
    33541 agggcatgct tgttggtcta gcaaggctga tggatgatag gatagggaat tgatgatttt
    33601 taaagatgca acagaaatgg cgcaggctgt tcgagaaggt agggtgagcc cctcagcctt
    33661 agtgagagac acaattaaaa aggctcaagc actcaatcct gagttgaatg ctattacctc
    33721 agagcgtttt tcagaagctc ttgctgaggc agcagcaagg gatttttctg gaaagccatt
    33781 tgctggtgtg cctatttttc taaaggattt agggcaggag caggagggcc aattggccac
    33841 tgcaggatca gtgttattta aggattatcg tgcctcaaaa acggattatg ttgtgcagcg
    33901 actagaggag ctgggcttta ttattttagg aagaagcaat acacctgaat ttggctttaa
    33961 aaatattagt gatagtcgct tacatggtcc ggtaaatctg ccacaggaca agagccgtaa
    34021 tgctggtggt tcatcaggtg gggcagcagc tcttgtgtcc tcaggaatca ccttgctggc
    34081 tcctgctagt gacggaggag gatccattcg gattcctgcc tcctttaatg gcttgatcgg
    34141 tttaaagcca agcagaggaa gagtgcctgt ggggccaggc tcttatcgtg gctggcaggg
    34201 ggcgtctgtt cattttgctc taacgaggtc tattcgagac acaagtcgtc ttctttatca
    34261 cttgcaggtt tatcaggtag aaagcccttt tccattagtg ccattaacca aagaagagct
    34321 ttttcaccct ttagacagac ccttaaggat tgctctttat gatcacatga tagatggaac
    34381 taccgcctct atagatgctc agacagcttt aaccgaggcc tgtcattttc taaaagagat
    34441 ggggcatgag gttgtgcgat tagataagct tcctctagat ataccaaagg ttatgaggga
    34501 ttactacctg atgactagtg ttgagacagc tgctatgttt gctgatagcc aagaagccct
    34561 tggtcgtcag gtgaccaaag cagatatgga ggtcatgacc tgggctatct accaagcggg
    34621 taaggatatt cttgcttcgg tctattctca ggcgctgcag cgctgggacc attatagtgc
    34681 tgaaatggca agctttcatg agcagtatga tcttttgctg acctttaccg ccaatacgcc
    34741 tgctccaaag catggacagt tccagccaag caaggagcta atagataagc tggctaaggc
    34801 ggaatgctac ccctccagtc agcgcctagc gctagtagaa gccatgtttg agcagagctt
    34861 gttcataacc ccttacacag ctttggcaaa tctgacaggc caaccagctc ttagtttacc
    34921 aacctatgaa acgtctgctg gattgccgat gggcattcaa ttgatagctg ctaaagggcg
    34981 agaagactta ttgctgggaa tagctagaca gtttgaacgg gctggattgt taaagctacc
    35041 tggttaaata ttataaaaca gagctaatct attataggtt agcttttttg ttaaatcgag
    35101 catatctagt ctcttataag attagtcaat gctatactgt cattaataat gaaaaaggag
    35161 ttcttgatga aaaaaggagt tgctttactt tctgttagct tggcgagctt gctgttagcc
    35221 gcctgtgggt cacagccatc agctcaaaaa acaagctggg aaaagattaa agataaaggt
    35281 gttttaaagg ttgctacgcc tgcgacctac cagccaacat cgtactataa tgatgccaat
    35341 gaattggtcg gctatgaggt tgacctgatg aaggaaattg ggaaacgcct tgatcttaag
    35401 gtgaagttca ttgaaacagg ctatgatcag gcttttactt cggttgatag cggtcgtgtt
    35461 gatgtttctc tcaataattt tgacattaca gccaagcggc aaaaaaaata caacatctca
    35521 acgccttata agtatggtgt tgggggaatg attgttcgtg ctgatggcag ctcaggcata
    35581 agcaaggctg acctaagcga ttggaaaggg aaaaaagcag ctggcgcctc tggtacagaa
    35641 tacatgaagg ttgccaagaa gcaaggtgct gaattagtca cttatgataa tgtgacgggt
    35701 gatgtttacc tgaacgatgt tgctaatggc agaacagact ttattcccaa tgattatcct
    35761 gcacaaaagc tttttgtgga ttacatgaag tctcaaaatc ctaacctcaa tgtcaaaatg
    35821 agtgatgtgc tgtataatcc gacagcacag ggcattatca tgagtaaaaa agatgacacc
    35881 cttaagaaaa agattgatgc ggtcatcaaa gacatgaaac aagatggcag cttgaaaacc
    35941 atttcaaaga catactatgc tggtcaggat ttgacagttc cttttggtaa ggacaagaaa
    36001 attccagtca ttgatgccag tgatgtggac tagtgcctta gacaaaggag ctctaaagcg
    36061 atgcttaatc ttagattgat actagagagc ttgggctttg ttttgtcagg tttgccctat
    36121 accttaggca tttctttttt aagctttcta acaggccttt tgctgggctt gcttttagcc
    36181 tttttaaggc gttctactag tcactttagt cattatctgg tcaggagcta tgtgtccata
    36241 atgcgtggcg ttcctatgat tgtggtgctc tttgtccttt attttgggct tccctattat
    36301 ggcttagaac tgtctgcctt gttatgtgcc tatttgggct tttcactggt tagtgcagcc
    36361 tatatctctg aggtctttcg tgcctcgatt gatgctattg atcagggaca atgggaggca
    36421 gcaagggctt tggggctgcc ttatgtcagc attgtcaagc atgtgattct gcctcaggcc
    36481 tttcgtattg ctattccgcc tttaggaaat gttgtgattg atatggtcaa aagttcgtct
    36541 ttggcagcta tgattaccgt tcctgatatt tttcaaaagg ctaaaattat tggtggcagg
    36601 gagtgggatt acatgtctat gtatatcttg gttgccttta tttattgggt gattgccttt
    36661 ttgctggagc gctgtcaggg ctttttagaa aagaggctgc gcttactctc ttaaaaaccg
    36721 aatatttacc ctagaaatat tgtatttcta gggtttttat gataaaaata tgatagacta
    36781 aagtagccta atcagttagt tagctttgtc aagaactgac tggctagagt gttggaggta
    36841 ggatatggca gactctattg tatttcggaa aaatcatatg atttcaactc aggcctttgc
    36901 tcgagtgctg gaagcctcag ggattaaaag accgactaag gacgaggcta gattatcgca
    36961 aatgctaaag cattccaatt atctatggac agcatgggaa ggtgacaagt tagttggtgt
    37021 tgctagagcc cttactgact atgcttatgt ctgctatatt tctgacctag cagttgatca
    37081 ggcatatcag ggtcaaggga taggcaagca attgctgtct tttatctcag aggatcttgg
    37141 agatgctgtt gctcttgtat tgctgtcagc accttcggcg atgtcctatt accctaagct
    37201 tggctttgaa caatcagaca aagccttcat tattccacga aaaccgtttt agagaggtat
    37261 ctaatgacac attcagcttg gcatgatgag attaagcaag tgttacctaa ggattattat
    37321 cggcgtatca atcgcttttt agatgaggtc tatgcgactg gagtggttta cccgcccaga
    37381 gacaatgtgt ttaaggcctt acaggtaacg ccattagaag agacaagagt gcttatttta
    37441 gggcaggacc cttatcatgg ccctcttcaa gctcagggac tttccttttc agtgcctgac
    37501 tccattcctg ctccgccatc tttgcaaaat attttggagg aattagcagc agatattgga
    37561 gtaaggaatc atcacgatct tagcagctgg gctgagcagg gagtgttgct cttgaatgcc
    37621 tgcttgaccg ttccagaagg acgcgccaat gggcatgcag gtctcatctg ggagcccttt
    37681 accgatgcgg ttataaaggt cttgaatgct aaggataggc ctgttgtgtt tatcctctgg
    37741 ggagcctatg cgagaagaaa gaaggccttg attactaatc cgattcacca tgttatcgaa
    37801 agccctcacc ctagccctct gtcagcctat cgtggctttt ttggcagcaa gcccttttca
    37861 agagctaacg ccattttaga aaaagaaggc ctaggacaga ttgactggct gcgctaggca
    37921 ttgaggcagg ctattatggc taagcaggac gatttaccaa taaagtatcc ggctttggag
    37981 acttgggtat acctagctaa atagagattg atgatatcag ggatcaagac agttacgtcc
    38041 gatatgtcaa gcaaaacaaa taatcactgc ctagataaat cagaaattgc tagggttatg
    38101 cttgattatc ctgataagca gataagtaga tttgacatag gaggggtcat gttattaatt
    38161 aaaaatgggc gtgtgatgga tccaaaatca cagctagatc aggtggcaga tgtcttaatt
    38221 gataatggaa ggattttacg gattgctcca gacattgagc atgatgaggt agagcagatc
    38281 gatgccagtg gacttgttgt tgctcctggt ttagtggata ttcatgttca ttttagagag
    38341 ccgggtcaaa cgcacaagga ggacattcat acaggtgctc tggcagcagc tgctggtggg
    38401 gtgacaacag tagtcatgat ggcaaacacc aatcctgtta tatcagatac ggaaacctta
    38461 caggctgttc tagcaagtgc tgctaaagaa aaaattaaca tttataccaa tgctagtgtg
    38521 accaagcggt tcaatggcca agagctaaca gactttaaag cgctcttagc agctggtgcg
    38581 gtcagttttt ctgatgatgg cattccttta gagagctcca aggtcttaaa ggaagcattg
    38641 gatttggcta aggccaacaa gaccttcatt gccctgcatg aggaggatcc ccaattaaac
    38701 ggtgtccttg gcttcaatga gcatatcgct aaggatcatt ttcatttttg tggcgctact
    38761 ggtgtggcag aatatagtat gattgccaga gatgtgatga ttgcctatga tcgacaagct
    38821 catgttcata ttcaacattt atctaaggct gagtctgtta aggtagttgc ctttgctcag
    38881 cagttaggtg ccaaggtcac agccgaggca acaccgcagc atttttctaa aacagaagac
    38941 cttttacggc ttgcaggggc aaatgccaag atgaatccgc ctctaagaac agaacaagat
    39001 agattagcag ttattgaggg gctcaaatca ggtgtcatag ctattattgc aacggatcat
    39061 gcaccacatc atcgtgatga aaaggccgtt gctgatctga ccaaggcacc atctggaatg
    39121 accggcttag aaacctcatt gtcattaggc ctgacaaatc ttgtggagcc gagccatctt
    39181 tcattgatgg cgttattaga gaaaatgacc attaatccag cctcactata tagctttgat
    39241 gctggttatt tggctgagtc tggccctgct gatcttgtta tttttgctga caaggaggag
    39301 cgtttggtaa cagaagcctt tgcttcaaag gctagtaatt caccttttat tggcgaaacc
    39361 ctaaagggag ttgtgaaata caccattgct aagggacaaa ttgtttatca ggcagacaac
    39421 taatcaacac ttaaaaagct gagcatctga tagtaactga tgctcagctt tttgatttag
    39481 tgatggcttg cgggctgctg cttgcttaag ttcaagcccc aaggaatgag attttcagat
    39541 tgctgcttga ttcgcttcat attatcctga tgccttagga taatgattgc tgctagcaca
    39601 acgatggtaa tggttaatag ccaatcgtag ctaggcaata aaaagtgggc ggcaggaaaa
    39661 gtcagaacgc taatcacagc tactacagac gctgttagac tagctagtga aatcatgcta
    39721 aataaataaa gcgttagcac aaacacagcc gctaaaaaaa ggagatagag tggggcaaag
    39781 cctagcaaga caccagcact ggttgcgact gcctttcctc ccttgaagcc agcgaaaata
    39841 ggaaaggtat gccctaggac agcaaaaaag ccaatagtaa ttggtgagat attgctagcg
    39901 ccaaccaaaa ccggaagaag cgtggcaagc gtgcccttaa aaatatcaat caataaggtt
    39961 gcagcaccag cttttagccc aagaatccga aacgtattgg tcgtaccggt attacctgag
    40021 ccatgctcac gcaggttgat gttatagaaa tactgtccaa tccataagcc tgttggaatg
    40081 gagccaagta aatatgctgt aagaattaat aggatcaatt tcataacata cattatatca
    40141 taatgattga tttaagcgga agcagttaca aagaattacg aaaaaatctt aaattatttt
    40201 gcaaaattct caaaaaacct gtaagataaa aaagatgaaa acgtctggag gtcaacttgg
    40261 ctaagaaaga aataagcata acaaattata atgatgatgc cattcaggtc ctagagggct
    40321 tagaggcagt tcgtaaaaga ccagggatgt atatcggatc aaccgatgca accggacttc
    40381 accatttgat ttgggagatt gtcgacaatg ctgttgacga ggccttatct ggctttggaa
    40441 atgagatcga tgtgacgcta aacaaggatg gttctgccac catttctgac agcggacgag
    40501 gcatgccgac cggacagcac gcccttggta taccaactgt tcaggtcatc tttaccatct
    40561 tgcatgcagg tggtaaattt ggtcaaggag gctataaaac ctcaggaggc ctgcatggtg
    40621 tgggctcttc agttgtaaat gccctatcgt catggctaga ggtggaaatc acgagagacg
    40681 gagcggttta caagcagcgc tttgaaaatg gcggtaggcc agtgacaggc ttagaaaaaa
    40741 tagctacagc tccaaaaagc aaatcaggga caagggttac tttcatgcct gatgacaaga
    40801 ttttttcgac aactgagttc aagtggaata ctatcgcaga gcgtctaaag gaatctgctt
    40861 ttctgctaaa gacggttaaa atgaccctga ctgatctacg aggtgacgat ccggtcgttg
    40921 aggaatttca ttatgaaaat ggtgttcagg attttgttgc ctatctcaat gaggacaagg
    40981 aaaccttgac tcctgtgatt tacatggaag ggcaggagca ggattttcag gttgaggtcg
    41041 ctttgcaata caatgatggg ttttcagata acattttgtc ctttgttaac aatgttagga
    41101 caaaggacgg tggcagccat gaaactggct taaaatcagc tattacaaag gccatgaatg
    41161 actatgcccg caaaaccagc ctactaaagg aaaaggataa aaacttggag ggctcagatt
    41221 atcgtgaggg cttgtctgca gtgttatcga tccttgtacc agagcagcat ttgcaatttg
    41281 aagggcaaac aaaggacaag ctaggaagcc cactggcaag gccgatcgtt gagagcattg
    41341 tatcagaaaa gctgaccttc tttttacttg aaaatggtga gctggcaggt catttgattc
    41401 gtaaggctat caaggcaaga gacgcgcgtg aggcagccag aagagcgcgt gatgagtctc
    41461 gaaatggtaa gaaaaacaaa aaggacaagg ggcttctttc tgggaaatta actccagccc
    41521 agtccaaaaa tcctaagaaa aacgagctgt acctagtcga gggggactca gctggaggct
    41581 cagctaagca gggcagggat cgtaaatttc aggcaattct ccccttacgt ggtaaggttt
    41641 tgaacacaga aaaggccaag atggctgata ttctcaaaaa tgaggaaatc aatacaatgg
    41701 tttataccat tggcgcaggt gttggtgctg atttcaatct tgatgatatt aattacgaca
    41761 agattattat catgaccgat gctgatacgg atggggctca tattcagacc ctgctgctga
    41821 cctttttcta ccgttatatg cggccgctgg ttgaagcagg acatgtctat attgccttgc
    41881 ctcctcttta taaaatgtca aagggtaaag gcaaatcgga gaaggtttcc tatgcttgga
    41941 cagatggtga gctggaggat cttcgcaagg aatttggtaa aggtgcaagt ctccaacgct
    42001 ataagggact tggggagatg aatgccgatc agctatggga aaccacgatg gaccctgaca
    42061 cacgaaccct tatccgagtg acgattgatg acctggctag ggcagagcga cgcgtttcag
    42121 tcctcatggg agacaaggct gccccacgcc gtcaatggat tgaggacaat gtcaccttta
    42181 ccttggagga aaatacggtt ttttaaggca tttttcctaa ggagggttct aaaatatctc
    42241 atatcaaatt gctattcatg tgctcagcat tcatttatca aggattgtaa tcattgaggt
    42301 aacagtgatg aagctagata tttgtcaaca aagctacagt cttcagtggg gaggcaccta
    42361 ttattttgca ttgacagatt atcccaatat caaggcttgg gaactggaaa agctagcagc
    42421 cttttgtgcc tacgaaaaat ggaatcatcg tcaaacagac attagctgtc aggacagcaa
    42481 gcttcttgaa gaggttcatc aatttcttga agcacatgct tgtgcctatc tctttaggcc
    42541 tagctgtaaa ttggtggctt caacatttaa catcaatgga gaggcagtct gttgtcctta
    42601 tttaagtcat acctgcactg tagcggctgc tctaagcatt tttaagacag gaaggctatt
    42661 gtctgctgta agagcttttg gggtaacggc acaggagttg gctaggagtg atcgaaatgc
    42721 tgctggtgat cctgctgatt attttcatta tgtgatgctt ggctggtcca atacgacctc
    42781 aggctatcgc ttggctatgg agagattgct taatcgtatg ccaaatgaaa aggacttaag
    42841 agagcatttt gtacccggag ttagctttca ctatagctat tctgatattt gtcagatgaa
    42901 aggctatgtt tttgatggct atcaccctgc caagatcaaa gacgagctta gtttggagga
    42961 attgcaggct tgcattattc ctaaaagctg gcagcagcgc tttgaagcaa ttattccaaa
    43021 ggccttacgc tcaagggttc attacctaga ctataaaggc gaaggcttgg tcgagtggtc
    43081 tgatagggtt tatcagctgt taagagtgat cagtgacagc tagctgtaaa taggctagct
    43141 ttatactatt ttttgaatat aatagacaat ctaacagaaa ggaaagctca gtgagaggtc
    43201 tcttgctggg tgtgggatgg atttcctaga aactgctaat cctagcgata ggggagcgta
    43261 gcgagcccat tctgaaagct cctgccgtag tgaaaagaag ataatcgctt acgattatct
    43321 tcgagggaaa tttcgagccg aagtctcgaa atttaggaat ggaaccgtag gttcgcttct
    43381 gtccccacta cctaaaggaa ctttcaaaaa aaactaatta aagaaagaga tatctttctg
    43441 aaagaaacaa agaaaggaat gttcagctag tttactaact gaacacggga ctatttttcc
    43501 tagaaaaatc ggtaacctcc tagtgtccaa ggacacgtcg tcagttccag cattttttac
    43561 ggaaaaattt cgcaagcgaa acgtcccttt gtatcttatg agtaatattc aaaacatgtc
    43621 ccttgaggac atcatgggag agcgttttgg acgctactcc aaatacatca ttcaggagcg
    43681 agcgcttcct gatattcgag atggtctaaa gcctgttcag cgccgcattc tttattctat
    43741 gaataaggac ggtaatacct ttgaaaaggg ctaccgcaag tcagccaagt ctgttggtaa
    43801 tatcatgggc aatttccacc cgcatggaga ttcttcgatc tatgacgcta tggtacgcat
    43861 gagtcaggat tggaagaatc gtgaaattct tgtggaaatg catggcaata acggctcgat
    43921 ggacggtgat ccaccggcag ctatgcggta cactgaggca agattatctg aaattgctgg
    43981 ttacctgcta caggacatcg ataaaaaaac agtgccattt gcttggaatt ttgacgatac
    44041 cgaaaaagag ccaacagtat tgccagctgc ctttccaaat ctattggtca atggctcatc
    44101 agggatctca gcaggctatg ctacagatat tccaccacat aatttgtcag aggtgatcga
    44161 tgctgttatt tatatgattg accacccaaa tgccaagctg gataagttaa tggagctatt
    44221 gccgggtcct gattttccaa caggtggtat tatccaagga gcagccgaaa ttaaaaaagc
    44281 ctacgaaaca ggtaagagcc gcgttgttgt tcgctccaga actgaaattg aggatctaaa
    44341 gggaggcaag cagcagatca ttgtgaccga acttccttat gaggtcaata aagctgtcct
    44401 agttaaaaaa attgatgatg ttcgggttaa taacaaggtt ccagacatag cagaggtgcg
    44461 tgatgagtca gaccgtacag ggctacgcat tgctattgag ctcaaaaaag acgctgacag
    44521 ccaaaccatc ttgaattatt tgttgaagta taccgagctt caagtcaatt ataattttaa
    44581 tatggttgcg attgatcatt ttacgcctcg tcaggttgga ttgcaaaaaa tcttatcaag
    44641 ctatatcgct caccgcaaaa gtattattat caagcgctct cagtttgaca aggaaaaggc
    44701 tgaaaagaga ttgcatattg ttgagggctt gatacgtgtc ttatctattt tagatgagat
    44761 tatcgcgctg atccgagctt ctgacaataa ggctgacgcc aaggaaaacc taaaggtcag
    44821 ctatgatttt tcagaggaac aagcagaggc tatcgtaacc ttacagcttt atcgactgac
    44881 caatacagat attgttaccc tccagcagga agaacatgac ctaagagagc tcatcacaac
    44941 tctctctgcc attattggtg atgaagcaac catgtataac gtgatgaagc gtgagctaag
    45001 agaggtcaag aaaaagtttg cagggccgcg tttatcagag ctgcaggctg aaagccaagc
    45061 gattgaaatt gattctgcta gtcttatttt ggaggaagaa acctttgtca gtgtgactca
    45121 gggaggctat atcaagcgaa caagccctag gtcatttcac gcctcaagcc ttgaggaaat
    45181 tggtaagcgt gatgatgatc atctgatctt tgttaagcag gctaagacaa cagaccacct
    45241 gttactcttt actaatttag gtaatgttat ttaccgtccg gtctatgagc tgactgactt
    45301 gcgctggaag gacatcgggg agcatttatc acaggctatt gctaattttg ctgctgatga
    45361 gctggtgata tatgctgagt tgatccagtc ctttgaagag ggactatata tctcagtgac
    45421 acagcatgga ctgattaaac ggtttgagcg caaggagctg acgccttggc gaacctacaa
    45481 atcaaaatca attaaatacg ccaagctaaa agacatagat gatcgcattg tggcaatagc
    45541 accaattatc atggaagatc ttcttttggt gacgcagcag ggctacgcct tgcggttttc
    45601 tagccaagaa ataccgattc agggcctaaa ggctgccgga gttaaaggaa ttaacctaaa
    45661 ggctcaggat tacttggttt ctgcctgccc agtcaatgct gattccttct ttgtgctgac
    45721 gcaaagagga gcactaaagc gagtggcgat tgctgatatt ccacagacca gccgagctaa
    45781 cagaggtctg ccggtgttac gagaattaaa gaccaagcca cacagagttt tcttggcagg
    45841 aatggtaaaa ggagatacta caacaggtac cattgactta tttacacatg attcagagga
    45901 cacagctagt gaccagcaat tagaggttat tagtaagact ggtcaacaat accagcttgc
    45961 tctcaatagc ctgtctctat cagataggac aagtaatggc tcctttattt cagagagcat
    46021 ttcagatcag gaggtcgctg ctgcaaggct catctagcca aagctttttc gctgtaccag
    46081 tgagggctct gagtctttca tcgaaaaaag atgcaaaaca atgaagaaaa gaatacaaaa
    46141 agaaaagagg taggataatg acaacagcta ttgattggga aaacttaggc tttgaatacc
    46201 gtaagctgcc atttcgctat gtatcatatt acaaggacgg caaatgggac gcaggtcgct
    46261 taacagaaga tgctaccctg cacatctcag aaagtgcacc agctctgcat tatgggcaac
    46321 aagcctttga aggcttaaag gcctatcgca ctaagaacgg ctctattcag ctatttcgcc
    46381 cagaccgcaa tgcagctcgc ttacaggcaa cagctgaccg tttgctgatg ccacaggtat
    46441 ctaccgagca attcattgac gccgttaagc aagtggtaaa ggcaaatgag gattttgtac
    46501 cgccatatgg aactggtgct accctttacc ttagaccctt gttaattggt gttggcgata
    46561 ttatcggtgt taagcctgct aacgaatata tatttatagt ttttgccatg cctgttggca
    46621 attactttaa aggcgggctt gcgccgacca actttatcgt ctctgaggat tatgatagag
    46681 cagctcctta tggcactgga gctgccaagg ttggtgggaa ctatgcaggt agcttattgc
    46741 caggaaaagc agctaagaca gcagggtatt cagatgtgat ttacctagat ccagcaactc
    46801 acactaagat tgaagaggtc ggagccgcta atttctttgg catcactgcc aataatgaat
    46861 ttattacgcc gcttagccca tcaatcttgc cttcaattac caaatactcc ttactccaat
    46921 tagccgaaga aaggcttggt atgaccgcta ttgagggtga tgtgccgatt aatgatttgg
    46981 accgatttgt tgaggcagga gcttgtggga cagctgctgt gatctcacca attggaggca
    47041 ttcagtatca ggataagcta catgtctttt acagcgagac tgaggttggt ccagtgacac
    47101 gtcgattata cgatgagctg gtcggtatcc aattcggtga tatcgaagca ccagaaggct
    47161 ggattgtagc tattgattaa aataagtgaa gcttgctatt gcaagctctt ttgattttgt
    47221 gtaaaataga caaggcgagg tgaagtgatg agtaaaaaag agaaaaaaat tgaactgcaa
    47281 ttatgcgatc aacaagtaac agtcaacaat accaagatag acggttatca gttacaaatt
    47341 ggcaagcgtg tcgttggcga gattgcagag cttgatggca agtttgctgt cttaaaagac
    47401 agcacagtag atgctttttt taaaacatta gagcaagcag ttgaaaatat tattgaaaac
    47461 tataatttga accactaaaa atgcttaaaa agacttgtca gcttacaaaa actatggtag
    47521 aatagttttt gttgttacgg aaagatagcg aagaggctaa acgcggcgga ctgtaaatcc
    47581 gctcctttgg gttcgggggt tcgaatccct ctctttccat gcctaagcta ttaggttcat
    47641 tgttttaatg atgatattgg ggtatagcca agcggtaagg caagggactt tgactccctc
    47701 atgcgttggt tcgaatccag ctaccccagt cagaggtatc agattagcgt ctgagatcgt
    47761 caaggataaa agttgttgtc attgcgggtt accttgagaa aatatattgt tatcaaaagc
    47821 tagcataagc tagcttttgt tggaggattt tttagaatga atgaatttga agatttgcta
    47881 aacagtgtta gcgaagtcaa tcctggtgat gttgtcactg cggaggtttt gacagttgat
    47941 aacggtcaag caaacgttgt tattgaaggc acaggtgttg aaggcgtttt gacacttcgt
    48001 gaattgacta acgatcgtga agctgatatt aatgactatg ttaaagctgg cgacaccgtt
    48061 gaagtgcttg ttcttcgtca agttgtaggt aaagatactg atacagttac tttcctagta
    48121 tctaaaaaac gtttggaagc tcgtaaggca tgggacaagc ttattggtcg tgaaggtgaa
    48181 gtcgttactg ttaaggggac tcgtgctgtt aaaggtggac tttcagttga atttgaaggg
    48241 cttcgcggat ttatccctgc ttcaatgatt gacactcgtt ttgttcgcaa tacagaaaag
    48301 tttgtcggtc aagaatttga cgctaaaatc aaagaagttg atgcagcaga aaaccgcttt
    48361 atcttatcac gtcgtgaggt tgttgaagaa gcagctaagc aagcacgtga caaagtcttt
    48421 tcaacacttt cagaaggttc agtggtaact ggtactgttg cgcgtttgac aagctttggt
    48481 gcttttattg atcttggtgg tgttgacggt cttgttcacg taactgagct ctcacatgag
    48541 cgtaatgtgt cgcctaaatc agttgtttct gttggtgaag aggttgaggt gaaggtactt
    48601 gctcttgatg aggaagcagg tcgcgtatca ctatcactta aagcaacaac acctggacct
    48661 tgggatggcg ttgagcaaaa gcttgcacaa ggtgatgtta tcgaaggtaa ggttaagcgc
    48721 ttgactgact ttggtgcttt tgttgaggta ttacctggaa ttgatggact tgtacacatt
    48781 tcacaaatct cacacaagcg tgttgaaaat ccaaaggacg tgcttactgt aggtcaagag
    48841 gtaactgtta aggttcttga cgttaacgct gctgatgagc gtgtatcatt gtcaatcaag
    48901 gcacttgaag agcgtccagc acaagcagag ggtgaaaagg aagaaaaacg tcaatcacgt
    48961 ccacgtcatc aaaaacgtga agctaagcgt gattatgagc ttccagaaac acaaactgga
    49021 ttttcaatgg ctgacctttt tggtgatatt gaattataat actataaaaa
//
LOCUS       DARYJX010000013        48757 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYJX010000013 DARYJX010000000
VERSION     DARYJX010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48757
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            110..637
                     /locus_tag="TU257_000719"
     CDS             110..637
                     /locus_tag="TU257_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL0833748.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TU257_000720"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TU257_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL0833749.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TU257_000721"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TU257_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL0833750.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TU257_000722"
     CDS             2207..2839
                     /locus_tag="TU257_000722"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL0833751.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TU257_000723"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TU257_000723"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL0833752.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TU257_000724"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TU257_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL0833753.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TU257_000725"
     CDS             3914..4657
                     /locus_tag="TU257_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0833754.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TU257_000726"
     CDS             4767..5867
                     /locus_tag="TU257_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL0833755.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TU257_000727"
     CDS             6223..6930
                     /locus_tag="TU257_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0833756.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TU257_000728"
     CDS             7071..7787
                     /locus_tag="TU257_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0833757.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TU257_000729"
     CDS             8009..8854
                     /locus_tag="TU257_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0833758.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TU257_000730"
     CDS             9226..10071
                     /locus_tag="TU257_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0833759.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TU257_000731"
     CDS             10149..11519
                     /locus_tag="TU257_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL0833760.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TU257_000732"
     CDS             11512..12576
                     /locus_tag="TU257_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL0833761.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TU257_000733"
     CDS             12577..13269
                     /locus_tag="TU257_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833762.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU257_000734"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU257_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL0833763.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TU257_000735"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TU257_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL0833764.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TU257_000736"
     CDS             complement(16695..17369)
                     /locus_tag="TU257_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL0833765.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TU257_000737"
     CDS             complement(17379..18755)
                     /locus_tag="TU257_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL0833766.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TU257_000738"
     CDS             complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TU257_000738"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL0833767.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKNHCKRL"
     gene            20126..20683
                     /locus_tag="TU257_000739"
     CDS             20126..20683
                     /locus_tag="TU257_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0833768.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20720..21613
                     /gene="htpX"
                     /locus_tag="TU257_000740"
     CDS             20720..21613
                     /gene="htpX"
                     /locus_tag="TU257_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL0833769.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21901..22434
                     /locus_tag="TU257_000741"
     CDS             21901..22434
                     /locus_tag="TU257_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL0833770.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22619..23305
                     /gene="covR"
                     /locus_tag="TU257_000742"
                     /gene_synonym="csrR"
     CDS             22619..23305
                     /gene="covR"
                     /locus_tag="TU257_000742"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL0833771.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23309..24799
                     /locus_tag="TU257_000743"
     CDS             23309..24799
                     /locus_tag="TU257_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL0833772.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24990..25484
                     /gene="nrdR"
                     /locus_tag="TU257_000744"
     CDS             24990..25484
                     /gene="nrdR"
                     /locus_tag="TU257_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL0833773.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25468..26631
                     /locus_tag="TU257_000745"
     CDS             25468..26631
                     /locus_tag="TU257_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL0833774.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26632..27540
                     /gene="dnaI"
                     /locus_tag="TU257_000746"
     CDS             26632..27540
                     /gene="dnaI"
                     /locus_tag="TU257_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL0833775.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27590..28900
                     /gene="der"
                     /locus_tag="TU257_000747"
     CDS             27590..28900
                     /gene="der"
                     /locus_tag="TU257_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL0833776.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29241..32333
                     /locus_tag="TU257_000748"
     CDS             29241..32333
                     /locus_tag="TU257_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0833777.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32537..33130
                     /locus_tag="TU257_000749"
     CDS             32537..33130
                     /locus_tag="TU257_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833778.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33174..34505
                     /locus_tag="TU257_000750"
     CDS             33174..34505
                     /locus_tag="TU257_000750"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL0833779.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34553..35035
                     /locus_tag="TU257_000751"
     CDS             34553..35035
                     /locus_tag="TU257_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833780.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35144..36718
                     /gene="mltG"
                     /locus_tag="TU257_000752"
     CDS             35144..36718
                     /gene="mltG"
                     /locus_tag="TU257_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL0833781.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36791..37273
                     /gene="greA"
                     /locus_tag="TU257_000753"
     CDS             36791..37273
                     /gene="greA"
                     /locus_tag="TU257_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL0833782.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TU257_000754"
     CDS             complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TU257_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0833783.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38517..38795)
                     /locus_tag="TU257_000755"
     CDS             complement(38517..38795)
                     /locus_tag="TU257_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL0833784.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            39088..39825
                     /locus_tag="TU257_000756"
     CDS             39088..39825
                     /locus_tag="TU257_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL0833785.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39864..40364
                     /locus_tag="TU257_000757"
     CDS             39864..40364
                     /locus_tag="TU257_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0833786.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40383..41072
                     /locus_tag="TU257_000758"
     CDS             40383..41072
                     /locus_tag="TU257_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL0833787.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41466..41708
                     /locus_tag="TU257_000759"
     CDS             41466..41708
                     /locus_tag="TU257_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL0833788.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41888..42682
                     /gene="racE"
                     /locus_tag="TU257_000760"
     CDS             41888..42682
                     /gene="racE"
                     /locus_tag="TU257_000760"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL0833789.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42679..43668
                     /locus_tag="TU257_000761"
     CDS             42679..43668
                     /locus_tag="TU257_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL0833790.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43644..44165
                     /locus_tag="TU257_000762"
     CDS             43644..44165
                     /locus_tag="TU257_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL0833791.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            44162..44623
                     /locus_tag="TU257_000763"
     CDS             44162..44623
                     /locus_tag="TU257_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0833792.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44620..45366
                     /gene="xerD"
                     /locus_tag="TU257_000764"
     CDS             44620..45366
                     /gene="xerD"
                     /locus_tag="TU257_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL0833793.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45366..46073
                     /locus_tag="TU257_000765"
     CDS             45366..46073
                     /locus_tag="TU257_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL0833794.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            46070..46609
                     /locus_tag="TU257_000766"
     CDS             46070..46609
                     /locus_tag="TU257_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL0833795.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46846..47568
                     /locus_tag="TU257_000767"
     CDS             46846..47568
                     /locus_tag="TU257_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0833796.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            47565..47843
                     /gene="yidD"
                     /locus_tag="TU257_000768"
     CDS             47565..47843
                     /gene="yidD"
                     /locus_tag="TU257_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL0833797.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48002..48550
                     /locus_tag="TU257_000769"
     CDS             48002..48550
                     /locus_tag="TU257_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL0833798.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT        13999 a         9070 c        11524 g        14164 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt tattaggaat accggctttt cgagggtact
    19321 tgtttggcgt ttcctttttc ttttcgacaa gagtgatata gcggccatct ccattaggaa
    19381 gttggtaggg ctggtgatca agcaccttag caaaaagtag ctgaagtgcc tttttagctt
    19441 cttctaattc ttggtccgct gcttgtgcct ttaaagcaat cagttttccc ttgattttta
    19501 aaaaaggaat ggtcaactca gacagaatct gcatgcgggc aacagctcta gcagttacca
    19561 aatcaaattg gccacgaaat tgcttgtctt gtccaaaatc ctctgcccta ccatgataga
    19621 aatgtactcc ctctaatcct agctctttag caaggagctg aagaaaatgt atgcgcttat
    19681 tgagagaatc aataatggta acatcaagct ttggaaacat aattttcata ggaatgcttg
    19741 ggaagcctgc tccagcccca atatctaaca gcctgagagg ctcatttgga atatatccct
    19801 gtaaaagcgg agcaacagag tcataaaagt gcttgagata gacttcattt tcttcagtga
    19861 tggctgttaa gttgatctta cggttccaat caaccaaaag cttaaaataa gtgtcgaatt
    19921 gttctttttg atgatttgtc agagcaaatc ctgcttgctc caggacaagg taaaaggctt
    19981 ggggtgtcat atatatcctc tgtttttaat taattgctac tattttagca taaaatagca
    20041 gaaaactgct gaaaagtccc ttcaatactt gctattaaac tgaaaattgc tataattgag
    20101 acacaaagat taaaggagaa ttacaatgcc aatgttttta gtaatagtag cccttatcgg
    20161 tgtgctggtt gtttggctga tggttagcta taatggcctg gttaaagctc gtatgcatac
    20221 aaaagaagct tggagtcaga ttgacgtgca gctaaagcgt cgcaatgact tgattccaaa
    20281 ccttgttgag acggtcaaag gctatgctaa tcatgaagag aaaaccttag aaaagattac
    20341 tagtcttaga tcacgtgtgg ctgatgctac tacaccgcag gccacaatgg cagcctccaa
    20401 tgaattgagc aagcaggtca ctagcctctt tgcagttgca gagagctatc cagacttaaa
    20461 ggccaatagt aatttcctaa aattgcaaga ggaattaacc aatacagaaa ataaaatttc
    20521 ttattcgcgt caattattta atacaacaac atcgcattat aaccttaagc tagaaagctt
    20581 tccgagcaat cttgtggcta aattgtttgg cttcaagcca agtgagtttt tacaggttcc
    20641 tgaagctgaa aaagaggttc caaaggtaga ctttaccgtc tagtctaatg cggctaatca
    20701 aggtcagaag aggacatcaa tgctttatca acaaatttca caaaataaac gacgaactgt
    20761 tatcctgctt tttgcctttt ttgtcttact ggtagtgatt ggcgctgctg ctgggtattt
    20821 actggctgac agctaccagc tgggggctgc ttttgctctg attattggtg ctatttatgc
    20881 ctttagcatg atttttcagt caaccagcct cgttatggga atgaataagg ctaaggaaat
    20941 cacagtaaac gatgctcctg atttctttca tattgttgag gatatggctc tggttgctca
    21001 gattccaatg ccaagagtat ttatcattga tgatccctca ctaaacgcct ttgccacagg
    21061 ctccagccct caaaatgcag ctgttgcggc aaccactggt ctactaaagg tgatgaatcg
    21121 tgaggagtta gaagcagtga ttgggcatga agtcagccat attcgtaatt atgatattcg
    21181 gatatccact attgcagttg ctttagctag tgctgtcaca ctgatttcca gcattggggg
    21241 gcgtatgatg tggtatagcg gtggcaggag acgtgataac gatcgcaacg ataatggctt
    21301 tggcgctatt atgctgattt tctcaatctt gtcactgatc ttggctcctc ttgcggcctc
    21361 tctggttcaa ttagccattt ctcgtcaaag agagtatctg gcagatgcca gctctgtcgc
    21421 gttaaccaga aatccagagg gcatgattag ggctctacaa aagctaagca attcacagcc
    21481 tatgactcat ccagtagatg atgctagcgc agccttatac atcaatgagc ctagaaaaaa
    21541 agaaaagctt agcgctttat ttagtaccca tccgccgatt gaagatagaa ttgaacgctt
    21601 gaagcatatg tgagagcttg agactagctc agctctcatt tttactagcc ataatgttca
    21661 gaaaacatca ttaattaatt gttttgaccc ggacattttt taagactttt atggaaattt
    21721 gggctatttt cataggggtt ttatggttaa acatttgatt gttggcttgt caatacttat
    21781 ttgtatccag acttaatgtt aaaaaaagtt atgaatttgt cataaagcta ttgacaaatt
    21841 cttgatatca tagtaaaaat agattagagt tttattagga agtgttttat aggagaaagc
    21901 atgttatctg tttcagatat tagaaagcga ccggaaggca ttcgctttga gagagagtac
    21961 gatgttaagg aagcgctgct tatacgtgat ccgcaggtta tagatattaa taacgtcaga
    22021 gcttcgggga gagctcagtt tgatgacggc ttgtatctat tagagtatca gctgggctat
    22081 cagattaccc tgccctcgag ccgttccatg gcgcctgttg tcttagatga gatgcagacg
    22141 gttcaggagc tgtttatcga ggaagcagat gtggcaagta agcaggaaat ggttgatgaa
    22201 aaccttgtct tagtcttatc agaggatcag cttgaccttg aagagagtat tattgacaat
    22261 attttgttgg cgattccctt gcaggtattg acagaggctg aaaaggagtc acaaatcttg
    22321 ccgacagggg aggattgggc agtcttaact gaggagcaat accaggccca gcagaaggaa
    22381 aaagcaaaag acaacagtcc ttttgcgggc ttacagggtc tttttgatga gtaaaaataa
    22441 aaattaaaga tgtctgtatt ttttatttga aaaaagaaca gttgtctggt atactttata
    22501 aatatacggc atattagtca ttttgatgac taaatagcaa tacttgatta atacaaaatg
    22561 gatgaatctt gtacatagct gataaggggc tgtgatacag gaagtaagga ttggtgtaat
    22621 gacaaagaaa attttaatta tcgaagatga aaagaatctt gcaagatttg tttcgcttga
    22681 gctacagcat gagggttacg aggtaaccgt cgaggttaat ggtcgtgagg gcttggagac
    22741 agccctagag aaggactttg acttaatcct tcttgatttg atgcttcctg agatggacgg
    22801 atttgaagtg acacgtcgat tgcaaacaga aaaaacgact tacatcatga tgatgactgc
    22861 gcgtgactct attatggacg ttgtagctgg cttggatcgt ggtgctgacg attacatcgt
    22921 gaagccattt gccattgagg aattgctggc gcgtattcgt gctatcttcc gtcgtcagga
    22981 cattgagtca gagaaaaaga ctcctagtca aggcgtttac cgcgacttag tcttaaaccc
    23041 tcaaaaccgc tctgtcaatc gcggtgatga cgagatttca ctgactaagc gtgaatatga
    23101 cctgcttaat attttgatga caaacatgaa tcgtgtcatg actcgtgagg agctcttgtc
    23161 taacgtttgg aaatatgacg aggctgttga aactaacgtt gttgatgttt atattcgtta
    23221 ccttcgtggg aagatcgata tccctgggaa agagtcttac attcaaactg ttcgtggaat
    23281 gggttatgtg attcgcgaga aataattgat ggcaaagcag aaaaaatata agaaaacgtt
    23341 accaaaacgt ttatcgaatc ttttgttcgt tctcttcttt tgcattttct ctgcctttac
    23401 cctactcgct tatatttcaa caaactactt tttgttgaaa cgagaaaagc aaactatttt
    23461 tcaggctgtt aacattgtta gagttcgtct ctctgaggtg gactctaatt ttacgttaga
    23521 gaatttagca gaggttctct ataaaaatga cagaacgcat ttaaagattg atgacgcaaa
    23581 tggtagtcgt attatcagaa gtgaacgaaa tatcaccaac acgctcaatg ccaatgagga
    23641 tatctatgtc tacaatgttg ataagcaaat gatcttcaca acagatgacg aagaggcctc
    23701 gccaggctta aatggaacta ttggtaaggt aaccaaggac cacattgagg agcaatacaa
    23761 gggcttttca atgactcaga aggtctactc taataagaca gggaagtttg taggctatgt
    23821 tcaggttttc catgacttgg aaaactacta catgatcaga gcacgcctct tcttttggct
    23881 tttggtggtt gagctctttg gggttggtct ggcgtatttc attatcttaa ttgtcacacg
    23941 caacttcttg aagcctctga acaatcttca tgatgtgatg cggacaattt ccaaaaatcc
    24001 agataatctg atgctgcgct cgggtatttc ctcgggtgat gaaattgagg aattgtccgt
    24061 tatttttgat aaaatgcttg ataagattga gacgcataca cgattgcaat caagatttat
    24121 tagtgacgtc agtcatgagc tgcgcacgcc agttgccatt atcaaggggc atattggatt
    24181 attgcagcgc tggggcaagg acgatagtgc tattttagat gaaagcctca ctgcagctgc
    24241 gcaagaggtt gaccgaatgg ctattatgat caatgacatg cttgatatga tccgagtaca
    24301 ggggtccttt gaagggcatc aaaatgatac aactgtttta gagagctcta ttgagaccgt
    24361 tgttggtaat tttagggtcc tgcgtgagga ttttgatttt acctggtact ctgaaaatca
    24421 aagaacccta gccaagattt ataaaaatca ttttgagcag gctctgatga ttttgataga
    24481 taatgcggtc aagtattcta ggaaggaaaa gaaaatcgtc atagaattag cggttaatgc
    24541 tagcaatgaa gctgtggtta aggtcaaaga cagaggtgag gggatctcag aagaggatat
    24601 taagcatatt tttgagcgct tctaccgcac cgataggtcc agaaatcgaa ccagcaccca
    24661 agcaggtctt gggattggct tatccatttt aaagcaaatt gttgatggct atcatttaca
    24721 tatggaggtt gagagtgagc taaataaagg gtcggtcttt attttgcgga ttcccttagc
    24781 tgatcatcaa ggctcatagc tgtatacctg cctgagtatc tagtagatgc tcaggctttt
    24841 gactgttcta atgtgtggtg tgatgatgag gtgtttatca gggaaggagg gctcttggag
    24901 gtaaacctga gtgcttgtct attcttttgt tatccctaaa attatggtaa aatagggtat
    24961 tagattaacg atagaattgg ggtgtttgcg tgcgttgtcc gaaatgtaac tataataagt
    25021 caagtgttgt tgatagtaga caggcagaag atggcaatac gattcgtcgc cgcagagaat
    25081 gcgaaagctg tcacacgcgc tttacaacct ttgagcgctt agaagagctt ccattactag
    25141 tgatcaaaaa ggacgggact agggagcagt tttcaagaga taaaatctta aatggtgttg
    25201 ttcaaagtgc ccaaaagcgt ccggtgtcaa gtactgacat tgaaaatctc atttctcgca
    25261 ttgagcagaa ggttcgtaca gcctatgaaa atgaggtgtc aagtactgtt attggcaatc
    25321 tggtgatgga ggaattagca gagcttgatg agattaccta tgttcgtttt gctagtgtct
    25381 ataaaagctt taaggattta gacgaaatcg aagagctctt acagcagatt actaatcgcg
    25441 ttagaggaaa aaagaagagc agtgtagatg atgaagccta ttgatacctt ttcttatatt
    25501 aagcataatc aggttcaata cgattcaagc agcctgattc agttgtattt tcctattatt
    25561 ggaaatgacg cagtggcagt ttatcagtat ttggttcact tttttgatga tggctcagga
    25621 gcccacaaat ttagtgatat tttaaaccat ctgcagtttg gaatgaagcg cctagaggaa
    25681 gccttggtga tgctgacagc tattgatttg ctggtcttat atcagctgcc agatgcttat
    25741 ttgataaaac tacatcagcc cttgggcagg gaagcctttt taaataaccc aatttatcgt
    25801 aggcttttag agcaaaagat tggagatgta gcggttttgg agttgcaaat ggtgattccg
    25861 aaccaggcta gaaacatctc aaagaccttt tcagatgttt ttggaataga ctctcaggag
    25921 cttaagcagc ctcagccatc aaagataaat tttgatttag atagctttca gcagctaatg
    25981 cggcgtgacg gtcttaggtt tgaggatcat caaaaggacg ttatcagtct ttacagtatt
    26041 tctgagcaat accacctaac ctggtttgac acctatcagc tggctaaggc aacagcagtc
    26101 ggcggcagca ttcgcccaga gcgcatgcta gtcaagaagc agcaagaggg cgctcaaaaa
    26161 acaagtgaat cgttctcacc agctgagcag gttgttctta gagagtctaa gcaggacacg
    26221 cctcttgtct ttttagagaa gatcaaaaaa gctaggcgag ctagagtcac aaaggacgaa
    26281 aaggaattgt tgctgactct agcccgcatg aatttcttgg acgaggtcat caatattatg
    26341 gtattatata ccttcaataa gaccaagtca gctaatcttc acaagactta tctgatgaaa
    26401 atggcaaatg attttgctta ccagcgggtt ttaacagcgg aaactgctat tatcaagaca
    26461 cgcgcctttg gtgagcgtaa gcagcaggca aagtcacagc agtccaatgt gcctaagtgg
    26521 agcaatccgg attatcaaga aaaaacaagt caggaagaac aggcaaagct agagcagttt
    26581 aagcaggctg ccttaaaaag gctggagaac ctaggaaaga gtggtgacta gatggaaaag
    26641 atcgggaaaa tggtagagca tttgggacag gctagtcgtg tagctagtgc tgagctgatt
    26701 gaggctatac ttgctgatca ggaggtggct gagtttatca aggctcacca gctatctcag
    26761 gcagaaataa agctgagttt atcaaagttc aaccagtttt tagttgagcg ccggaaatac
    26821 cagacaggtg atgagaccta tattgctaag ggctatcagc ccattttggt catgaacgag
    26881 ggctatgcag atgtgtctta cctagagaca agagagcttg ttgaagccca aaggcaggca
    26941 gctattgcag atcggattca tttggttagt ctgccaagat cttatcgtag ggtttctttg
    27001 tcagctgttg atgttaacaa tgccagtcgt atgcaggtgt tttcagagct tttggatttt
    27061 gttgagcagt atccagcggc agagcaaaag ggtctctacc tttatggcga tatgggggtc
    27121 gggaaatcct atctgatggc tgctatggca catgaattgt ctgaaaaaaa gggtgtatca
    27181 acaactcttc ttcattttcc tagctttacg attgatgtta aaaatgccat ttcaaatggc
    27241 tctgtcaaag aagagattga tgccatcaag catgtccctg ttttaatttt agatgatatt
    27301 ggtgcagagc aggcgacctc atgggtgcgt gatgaggtgc tacaggttat tttgcagcat
    27361 cgtatgctag aggatttgcc aacctttttc acctctaatt acagctttgc agatttggag
    27421 agaaaatggg caaagatcaa aggaaatgat gagacctggc aggccaagcg tgttatggag
    27481 cgtgtgcgtt atttagcacg tgaatgccat ttagaagggg ttaatcgccg ccagggctag
    27541 ctaaacgcta gctcaagcga tggataatga gataaagaaa aggagaatca tggttttacc
    27601 tacagttgcc attgttggac gtcctaatgt tggaaagtcc acgttattta accgaattgc
    27661 aggagagcgt atttctatag ttgaagacgt cgaaggggtt actcgcgacc gcatttacac
    27721 gactggtgag tggcttaacc gccaattttc attgattgac acaggtggta ttgatgacgt
    27781 tgatgctccc tttatggagc aaatcaagca tcaggctcat attgcgatgg acgaggcaga
    27841 tgttattgtc tttgtggttt ctggtaaaga gggcgttact gatgcagacg aatatgtctc
    27901 taagctcttg tatcgtacca acaagccagt gattttggtt gtcaacaagg tggacaatcc
    27961 agagatgcga aacgatattt atgattttta ttctcttggc ttaggagatt ccttcccggt
    28021 atcatcagtt catggtattg gtacgggtga tgttttagat gctatcattg ataacctgcc
    28081 gatagaagag ccagtagaaa acgacgatgt gattcgcttt agcctaattg gacgtccaaa
    28141 tgttggaaaa tcaagcctca ttaatgcgat cctaggagaa gagcgtgtca ttgccagtcc
    28201 tgttgctggt acgactcgtg atgcgattga tacaagcttt accgatgaat ccggtcaagc
    28261 ctataccatg attgataccg caggaatgcg taagtccggc aaggtctatg aaaatactga
    28321 aaaatactca gtgatgcgtg ccatgcgtgc cattgaccga tcagatattg tgttaatggt
    28381 tattaatgcc gaggagggca ttcgtgacta tgataagcgg attgcaggct ttgcgcatga
    28441 ggcaggtaag ggcatgatta tcgttgttaa taagtgggac accatcgaaa aggataatca
    28501 tacagtagct aggtgggagg ctgatattcg tgatcaattt caatttttga cctacgcccc
    28561 tattatcttt gtttctgccg ttacaaagca gcgcttaaac aggcttcctg agttgattaa
    28621 gcgtatcagt gatagtcaaa gccagcggat ctcgtcagct attttaaacg atgtgattat
    28681 ggatgctatt gcgatcaacc caaccccaac ggataaggga cggcgtctaa agattttcta
    28741 tgctacacag gtttctgtga agccgccaac ctttgttgtt tttgtgaatg aagaagagct
    28801 gatgcacttc tcttatctgc gctttctaga aaaccagatt cgtgctgctt tcacctttga
    28861 agggacacca atcaagctga ttgcgcgcaa tcgcaaataa gcccttttat tactcttgtt
    28921 agtattggaa gcagcgagtg ctgttgatgt gcggtgtcta gaccttgtgt gtcaggactt
    28981 ttgaccgacc aataagcctt accagaaatg agaggctgct atccaaatag agcttaccag
    29041 caagcaaggc gtgccaagca ttgatgtcac atgataatca ttagccctag gctagtgatt
    29101 ttttagtgct ttaaagccta tcagaacagc tatatacagc tactcaaata tgttttaata
    29161 gcctttaaga gagatttttg caggaaatct aagctgaagt ttgttataat caaaggataa
    29221 gcaaaaaggt gggagcagat atggctagat taattccggg gcggattcgc aatcaaggca
    29281 tcgagcttta tgagcaaggc ttggtgaaaa tcatagatga caggactgac cttcttcgag
    29341 cagaggtgga tacttatcag gttcaatatg gtatcaatga tgaggatatt aggtgtcagt
    29401 gtgattattt tgagcgaaag cagtattgcc agcacattgc ggctctagaa tattttctga
    29461 aaaataatca gaagggcaag tcgctctcag agcagcttaa caaccagctg gaaagtaagg
    29521 aggaaactaa aaagctgacc tcctttggta gtcttttttt ggacagtttg cacatgaacg
    29581 aggacgacac gaccaaatat aggcttttag cttctggtgc taaaagtcct ttctcatctg
    29641 attactggtg gagccttaag ataaatcgct tgcccggaga gaaggcttat gttatccgcg
    29701 atatcaaggc ctttattcat ttggtcaaag ttgagggctt ttaccagatt ggaaagaatt
    29761 actttgagtc tctttccata ttgcagtttg atcaggctag tcaggagctg attcgttttc
    29821 tttggcgttt atcaacgcat tcagataagt tagattacga atggctattt cctaaccacg
    29881 ctcgtcatct tcggttaccg gcaggctttt ttgaggaggg cattgacctg ctgacggggc
    29941 tttacgagtt ttcatttgag acctcctctc aaacctattc tcatctttat gttcgacctc
    30001 tggaggcaga ggctggtctc tttcagttta cagttgatgt tcatcgcagc tctattgagc
    30061 tttacattaa ggaaaaaaat atagagtatt ttttcaataa tgaatacctg ctatacatga
    30121 acacctttta ccacctgagc ctgaagcagc aaaaaatggt tcaagctatt cgcagcctgc
    30181 ctattgaggc cgatttggcc aagcacattc attttgatct tgatgatcag gctaagctgg
    30241 cagctagctt gctggaattt cgagagcttg gtcaggtgaa ggctcctaaa agctttgata
    30301 ttagagattt ccaagtgact tttgtctttg atattactga aaaaggtgag ttgacctctc
    30361 agctgatttt tgactatggg agcattcaga tcagtgataa ggcaagctta gaccagctcc
    30421 cctttgctag ccattataaa aaagaaagca gtatttatcg tgccttgaag cgctttgggc
    30481 tttctccgca gttttttgct aagaaagcct tgactgaccc caaggactgg tatcgctttt
    30541 ttacagaagc tgttccttat tttgaaagtc taggtagggt tcagctttcc tctaagctcc
    30601 aagatcagcg cttaatggaa agccctcagc ttacagtcaa acgtgaggga ggtcttttag
    30661 atatttcctt tgatttttca acggtttgtc agactgatat tgaaaaggct ttggccactt
    30721 tgtttagtga tcgctcttat tttgtcaatc agtcaggcaa gctggtcgtt tttgatgaag
    30781 agacacaaaa aatcagccgt agcttacagg aactaagagc taagcagctg gcaaatggtc
    30841 acctccagct agaaggaata gctgccaccc agctgtctca tctattttcg gatctgtctt
    30901 ctgttcattt ttctgaggag ctagagaccc taatcaagga cctgcagcac ccggatcgct
    30961 ttgagctggg agagctggcc gttaaggcca aggtgagaga ttatcagctg cagggcatca
    31021 aatggctctc tgtgcttgat aagtatggct ttggtggtat cttggcagat gatatgggct
    31081 tgggcaagac actgcaaatc attgcctttt tatcaagcag gctaaccgag acctccaagg
    31141 tgcttatctt ggcaccctct agcttgattt acaattggtt agatgagttt agtaaatttg
    31201 cccctcagat agatgctgct gtatcctacg ggctaaagcc ggcacgagat gctcttattc
    31261 aagaaggaca tcaggtgacg attaccagct attcttcctt taggcaagat ttagaaacct
    31321 atcaggcaaa tgattatgat tatttaatct tagatgaggc gcagatgatt aaaaatgccc
    31381 agaccaagat tgctcagagc ctgcgtgcct ttgacgtgaa gaattgcttt gctttatctg
    31441 gtacgccgat tgaaaataag ctgcttgaaa tctggtccat ttttcaaatt gttctgccag
    31501 gcctgctgcc atctaaaaaa gcctttttga aaatggaggc cagagacgtt tctcgctata
    31561 ttaagccctt tgtcatgcga cgcaaaaaag aggaggtctt gccagagcta ccagaattaa
    31621 tcgagatgaa ttattacaat gagatgtccg atggtcaaaa agcgatttat ctggcacagc
    31681 taaggcagat gcaggagcgg ctgtctgctg caactgatga tgatattaat cgcagtaagc
    31741 tggaaatcct gtctggtatc acacgtctaa ggcaaatctg tgatactcct agcctgttta
    31801 tggattatca aggaggaagc ggtaagctag acaatctaag aaccttgctg ctgcaaatta
    31861 aagaaaacgg tcatagggct ttgctgtttt cacaatttaa gggcatgctg gctcttgtca
    31921 agcaggaaat ggatcagctt ggcttatcat cttataccat aacaggctca acaccggcca
    31981 atgaccgtca agaaatgaca cgtgccttca ataatggctc aaaggacgcc tttttgattt
    32041 ccttaaaggc cggtggtgtt ggactcaatt taacaggtgc tgatactgtt attttgattg
    32101 atctatggtg gaacccagct gtagaaatgc aggccattag tcgtgctcat cgtattggtc
    32161 aggaggacaa tgtagaggtt taccggttga ttacccgcgg aacaattgag gaaaaaatac
    32221 tggagcttca ggaaaataag cgtcatctga ttaccactgt tttagatggc aaacaaggcc
    32281 tagcaagcat gtctgtcgag gagatcaaag aaatccttgg tcttcagccc tagcatgtat
    32341 ggcttttagc acacgctctt aagcctatca gctaaaggct agtgtctgtt ctctataaca
    32401 aataaggcaa gagaatagag gtgatgagct agtcacatca tttttgcttt gctgcctttc
    32461 tttttaggaa ttactttgaa aaataggatt atttagttta taatagggaa tgctatagga
    32521 aggagagtga gatagaatga caaagcatgc gtttcctctg gttgcagatg gtgagcctat
    32581 tattgagtca gctaggcaga tggctttata tgaaaacgaa gatttgatca caaatattgc
    32641 tggcagctat caagataaac attacgacga catcataaga gaccatcaat ttgctgagaa
    32701 gactcctgtc gtctctaaag gatcccttca tcattctcca gttgtcgatg aagatcatag
    32761 ctacgctcaa aaggccagaa ggcaagcaaa gcaggatgtc aaagaaaaaa gacaggctta
    32821 tattgctaaa aatatggctt atagcccaaa gcaggcaagc aagaaaggtc aaagtggggc
    32881 cttctcttct aaaaaaccag cgacagaatt gagccgtttt acagagaaat taaaccaaga
    32941 gtcttatatt ttagctgagc ttcctcgtca atataaggag ccgcaaaata ccagccaagc
    33001 agctgtcaaa aaaaataatt atgacttttt gaagcgcagc caaatctaca atcatcaaga
    33061 agacagagat catcgtgaaa agaccattgc tcaagagcta aacctgagtc gctttgaaga
    33121 tattaagtaa gctttataca gccttatgtc tgtcaacatt aaaaggagtt aacatgtcaa
    33181 aaacctatca ttttatcgga attaaaggat ctggaatgag tgccttagcc ctgctgctcc
    33241 atcaaatggg gcataaggtt caaggcagtg atgtggagaa gtattatttc acacaaagag
    33301 gcctagagca agcaggcatt accattttgc cctttagcga agataatatt tctccggata
    33361 tggagctgat agcaggtaat gcttttcgtg aggacaacaa tagcgaggtt gcttatgcga
    33421 tgcgtcatca gctgcccttt aaacgctacc atgagttttt aggtgagttt atgaagcagt
    33481 ttactagtct tggtgtagcc ggtgctcatg ggaaaacctc taccacaggc ttgttgtcac
    33541 atgtgctcaa gcacatgacg gctacttctt atttgattgg tgatggtact gggcatgggg
    33601 ctgccgatgc tcgttatttt gtgtttgaat cagatgagta cgagcgtcac tttatgcctt
    33661 atcacccgga atattctatt atcactaata ttgattttga tcaccctgat tattttacag
    33721 gccttgatga tgtgttcaat gcctttaatg actatgctaa gcaggtgaaa aaggctcttt
    33781 ttgtttacgg tgaagatgag gaattaagaa agattagctc tcctgcaccg atttactatt
    33841 atggctttga ggacactgat gatttcgtag cctttgatat cacacgcacg acaaatggct
    33901 cagactttaa ggtaaagcac aagggtcatg ctattggtca gtttcatgtt ccagcctatg
    33961 ggcgtcacaa tattttaaat gctactgcgg tgattgctaa tttatttatt gcaggctttg
    34021 atatgaagct tgttgcagag catctgaaga gcttttcagg ggtgaagcgt cgttttactg
    34081 aaaaggtgat caatgacact attattattg atgactttgc tcatcaccca acagaaatca
    34141 ttgcaacgct tgatgctgct aggcaaaaat accctaataa ggaaatcatc gctatttttc
    34201 agccacacac ctttacaagg accattgctt tgctagatga ctttgcccat gccctaaatg
    34261 aggctgacag tgtttatcta gcgcctatct acggctcagc gcgtgaggtt gataagggtg
    34321 atgtcaaggt ggaggatcta gcggctaggg ttgagcgccc agccaaggtc atctcagttg
    34381 acaatgtatc gccgctgctg gatcatgata atgcagtcta tgtttttatg ggagcaggtg
    34441 atattcagtt gtatgaacgc tcgtttgaag agctgctggc taacttaact aaaaataatc
    34501 aatgattaag cgacctgcct taggcaggtt ttctcgtcgt aaaggaggac ctatgctaat
    34561 tagacatgtg aatcagactg actgggagat tattgctgat atcgaacagg ccaatttttc
    34621 tccccaagag gctgtagcag ccaatgtgat aaaagagcgt gcagagctta tttcggatac
    34681 ctttcttgtg gctgttatcg ccaatcagtt tgtcggctat atcgaaggac ctgtcattgc
    34741 tgagccaagg cttgaggatc acctatttca tggtgtgacc aagaatccag caagaggtgg
    34801 ctatatagcc attaccagtc tttctgttgc tcctggatac caaaagcagg ggattggcac
    34861 agctctctta gctgcaatga aggatttagc agttgcacag gatcggctgg gtatcatact
    34921 tacctgtcat gactatttga ttccttacta tgagatgaat ggttttcaag atcaaggcct
    34981 gtcagcttca aagcatggtg gctctgtttg gtatcaaatg ctatggcagc cataggaagg
    35041 ctattaaagc ttagcatgta ttaagaatta gtaacaaaag ggggatttta ttgcatttat
    35101 agtgcaatta ggatataatg gcggttgatt aagtttagga ggaatggctt tgactgattt
    35161 taaagatgat gagcaaagac gtcagcagca aaaaagcttc aaagaaaaga ttctagccga
    35221 attagaaaaa gcaaatcaga ttagaaaaga aaaagaagaa gagcttttta aaaaggatct
    35281 agaggttcaa gaggctgcta gaagaacagc tcagctttat gcagaatata aaagacaaga
    35341 agcactaagc aataacccca aacaagcgtc tgatatagca gctgcgtcgc aagagacgac
    35401 ctcaacggct tcaacagccc acacctctgc gattaagcta gaagagacag cagtagctac
    35461 tggggatcaa gcattgtcgc caccagagga gcctgcattg agtgaaagcc tgcttaagga
    35521 agaggcaagt gtcgaaggtc agactaagaa gggtggtcca gtgagaagaa aaacaagtaa
    35581 gcgccagcag acagatcgaa tggccaaaaa aatttcgaca gtactgatat cgtcgattgt
    35641 cgctattatt gtggtgattg gcctcgcagg gacagcctat gtgtatagtg cccttaaccc
    35701 tgttgacaaa aatagcgatg actttgttca ggttgaaatc ccagccggct caggcaataa
    35761 gcttattggg cagatccttg aaaaagaggg gctgatcaaa aatagtaccg tctttagctt
    35821 ttacactaag tttaaaaatt tcactaattt tcaaagtggc tactacaacc tacaaaagag
    35881 catgagccta gaagacattg cccaggcctt acaagagggt ggcacagcag agcctacaaa
    35941 gccagtacta ggaaaaattt taattccaga gggctatacc attaagcaaa ttgctaaggc
    36001 catagaaact aatagtaggg caaagaatcg tagcaaggct aaaacaccat ttcactcaaa
    36061 ggatttcttg aatttggtga caagtgatgc ctttattcaa gagatggcta aaaaatatcc
    36121 gaaattgcta ggagatcttc caagcaagga agtagctact tatcagctag aaggctacct
    36181 tttccctgcg acctataatt attataagga aacaacacta aaagaccttg cagaggaaat
    36241 gattgcagcg gcaaatgcaa acctagcgcc ttattatgag gcgattgcag ctagtggcaa
    36301 gacagttaat gaggtgctga ctttggcctc cttagttgaa aaggaaggct ctactgatga
    36361 cgatcggcgt caaattgcca gcgtatttta caatcgctta aataatggca tggccttaca
    36421 gtctaacatt gctatattgt atgcaatggg taaattggga gaaaagacaa ccttagcaga
    36481 ggacgctgct attgacacaa ccattaattc tccttataat gtttatatca atactggctt
    36541 aatgcctggt ccagttgata gtccagggct tgcagctatt gaggcgacta tcaatccagc
    36601 ggcaacagat tacgtttatt ttgtagccga tgtgcgtact ggtgaggttt attatgcaaa
    36661 aacatttgaa gagcactctg caaatgttga aaaatatgtt aacagtcaaa ttcagtaagg
    36721 acaaacatgg tgctttagca tcatgtttgt gtttctgatt cgtcaaaaga aaaaggaaaa
    36781 gagaaagata atggcagaaa agacttatcc aatgacagca gcagaaaaag aacagcttga
    36841 aaaggaatta gaagagctaa aattagttcg tcgtccagag gttgttgagc gcataaaaat
    36901 cgctcgttcg tatggagacc tttctgaaaa ctctgaatac gatgctgcta aagatgagca
    36961 ggcttttgtt gagggacaaa tctcaacctt ggagacaaag attcgctatg ctgagattat
    37021 tgatagcgat gctgttgcca aggacgaggt ggcgattggt aagacagttg ttgtccagga
    37081 ggttggcaca caaacaacag acacttatca tattgtcggt gcggcaggag cagatatttt
    37141 ttctggaaag atttcaaacg agagtccaat tgcacaggcc ttgattggta agaaaacagg
    37201 agataaggtt aagattgagt ctccagcagc tacctatgag gttactatca tcagcgttga
    37261 caaaacacaa taagacttat ctgactatca gtgcagtgtc ctgatagtct ttttagtggc
    37321 ttgcttttta atatcagttg ttgtggtcta ttaaaaagag ctgcacttta gaaagtttta
    37381 actaagatac tttatgacct agtctcatac attaaaaaag cgaacaggtc taattttcgg
    37441 aatccctgaa aattagacct gttcgtttgt tttatcttga gtcagacttt tgtcacagac
    37501 tcttttagct atcttagcga cgcttttttt gtttaccggc gtttcggttt aacttagtcc
    37561 tcttgcttgt gctaagggct tgcttttcag ctgtaacgtc cttgcgtggc tggtgagatt
    37621 tataggcctt aggagggttc tttgcgaact cctctgcaat ttgcttgcgg agccttggtt
    37681 ttaaaaggta ggttgtgatc aattgctgaa tgatactaaa gaaaccacca actagccaat
    37741 acaagcctaa tccggcaggc aggtaaaacg acatgacaat catcataatt ggcatggtgt
    37801 acagcatggc tttcatttgt tcacgttgct cctcagggac tgccatcatt gacagccagg
    37861 attgaacgaa gtataaagcc gcaattacag ctgtaagcaa gacgctgcga tgccccaggt
    37921 caatgcccat aaaggtactt gttgagactc ccttggtaaa ttggaccgca acatacatgg
    37981 cagaaaagaa aggcatttga atcagcagtg gcaaacagcc tataccgcct agcgggttga
    38041 ctccattttc acgctgggcc gccattaatt ctgtttgggc tgccattttt tcttcagtgc
    38101 ttgtagcgtt tttgatgcgt tgattaattg gctcaaaaaa aggctttagg taggccattt
    38161 tttctgattg gtagcttgcc ttccatgatt ggtagagccc aagtggtagg ataatcgttc
    38221 taacaataat agttacaaca atgatggcaa gaccatagcc tagggcggtg ctgttagcaa
    38281 agtaatcaat gagaaaggaa acgggctttc caaggtaatc ccaaatgatg ccctccgggt
    38341 gccccttggc gtctctgccg acacaccctg tcaatgtcag taggaccgat aaggcaagtc
    38401 ctgagaaaag tatgcgattc gttttgagtt tcaatgtgtt tgtcctttaa tttttaatat
    38461 acctaaccat tttactgttt ttttgagaaa ttaacaatag ttctacagta ggatttttaa
    38521 ttgctgatcc taaaatcatg gaaatcctca aagtgagatg gattaacatc aacataggtc
    38581 acctttgccc atttagaagg tccttttctg atttcctgga taaagcgcgt catctttgca
    38641 gggtcactag cctgtgctaa aatctcaaca gtcccatcac tattgttcca cacgcggccg
    38701 taaatatcac caatttccaa agctagtgcg taggttgaat agcgaaagcc aacaccctgc
    38761 accctgcctg aaacgattag tctgaccttt ttcataagtc acctcttttc tttttattat
    38821 agcatagata gcttataaat actaaaagtt gtcatggagc aggcagccaa aggataggca
    38881 aagactgcaa gtgggctatc tgctgaggta aacaataggt cttagtgcag caaggctatg
    38941 tttatggtta gctctccttc ttgtcttcta aaaaggaaag ctaatgggct tacgacacct
    39001 gataagggga gaaagctcct tttaggctga tagccttctg atggttttta tgcaaaagag
    39061 tgaacaattt tgtgatataa taagaccatg attatcacat caaaagcaaa ccatttgatt
    39121 aagcaggcta agaaattact gcaaaaaaag catcgcaagc actcttactt gattgagggc
    39181 tggcacctat ttgaggaggc tcagagatct gggcaggaat tgatacatat ttttgttctg
    39241 gaggaaatgg cagagcgctt atcaggcttt gatcaggttg tcatcgtcag tccagagatt
    39301 ctaaaggagc tgacgagctc tcccaatcca cagggcatta ttgctgaggt taagctttgt
    39361 caacaggcct taccgactag ctatgctgga aaatatttga ttttagagga cattcaggat
    39421 ccaggcaatc tagggacaat cattagaaca gcggacgcag caaagtttga tggggtgttt
    39481 ttgtctgaga agtctgcgga tgtctacaat caaaaaactc tacgctccat gcagggcagt
    39541 cattttcacc tgccgatttg gcgaacggat atttatcagg tcagtcaggt gatgcagcag
    39601 caaaaaatac cagtgctagc aacgaccttg tctcaggatt cgattgatta caaggacctc
    39661 tcagctagga gcagccttgc ccttgtttta ggaaatgaag gtcagggcat tagtcctgag
    39721 atggcagctt tggctgatca gctgattcat attagcatgc ctggacaagc tgaaagctta
    39781 aatgttgcag ttgcagcagg aatcctcatt ttcagcctaa tttaagctag tatggtataa
    39841 taatgatgtg aggtgattag tgtatgcatt atacagaaga tacagaatac atggagcatg
    39901 ttggtcattt gattgctcac cctcgctttc aaaggcttgg agatattgtt cagcatcacc
    39961 attctactcg cttagagcac tctgtcaatg tttcttattc tagctatagg ctggcaaaga
    40021 ggcttggctt agacgccaag agtaccgcac gaggtggctt gctacacgat ttcttttatt
    40081 atgattggcg agtaaccaag tttaacaagg gacacgcttg ggtgcaccct agaattgctg
    40141 ttcgaaatgc taaaaaatta acagcactca acaaaaaaga agaggatatt atcctaaagc
    40201 atatgtgggg agctactatt gcttttcctc gctataagga aagctatatt gttacctttg
    40261 ttgataaata ttgggcggtc aaggaggcca tgacgccgct gcgtcaaaaa tggacgaacc
    40321 gtcgcttcct gcgtcgaaag acgcttcaaa gtcacaatca ttaagtaaaa aaaggagtta
    40381 tgatgaacga taatgttatt tacacacagt ctgacgcagg cttgagccat ttttttgcca
    40441 aggtctatag cctggttggt atgggagttg ggctttctgc ctttgtttct tatttgatgc
    40501 tgtttccatt taggcaaaat ttagtctcga ttgttcttga tcatcctatg gtctattatg
    40561 gggcggctat tgttgagctt gtactggttt ttgttgctag tggtgctgca cgtcgcaata
    40621 caccagcagc tttaccctta tttcttgtct attcagcctt aaatggcttt accttgagct
    40681 tcattattgc agcttatgcg caaacaacgg tgctacaggc ctttatctca tcggcagctg
    40741 ttttctttgc tatgtcactg cttggtgtta aggttaagcg tgatctgtca ggtattcgaa
    40801 aggccatgtt tgcagccttg attgggatta tcgtggctag tctggtaaat ctctttatcg
    40861 gtagtgacct gatgagctat gtgatcagcc ttatttcagt gttgatcttt tctggcttga
    40921 ttgcttcaga caatcagatg atcaagcagg tctaccaagc ctctaacggt caggttggtg
    40981 acggctgggc tgtcgctatg gctcttagct tatacctaga ctttatcaac ctctttatca
    41041 gtctacttcg tctcttggga agaaatgact aatagctatt ttaagcgcag ctgctgattg
    41101 tcacttaatc gctattacga gaaatcagcg aagctgcagg tgttaccttt tgttagaaaa
    41161 gagtggctgc tgctagtaag aaagtagctg ctaggagagc ctgatgagcg tgactgtcaa
    41221 ggaaggccag ttactattgc taccatctag ggaaggtacc aaaaaaagtc aagaagcggg
    41281 cccaagggct cgtttttgtt tgcttgattt gtggtaaagt gcttcaaacc aagcctatat
    41341 ctagtctgat agctcttatc agctgacaac atcatattta caatgcctgt tggtgtagat
    41401 ttgtaaagca tgctcttttt tggtataatg agaggaacaa aaaatcgagg agaatatcta
    41461 tcaatatgtc tacagctatc tggatattat taatcattgt tgctcttaca gccggtcttt
    41521 ttggtgggat ttttattgcc cgcaagcaaa ttgaaaagga aattggagag cacccacgat
    41581 taacgcctga ggccattcgt gaaatgatga gtcaaatggg tcaaaaacca agtgaagcga
    41641 aaattcaaca aacttaccgc aacattgtca agcaatcaaa agccgcaatg actaagggta
    41701 aaaaataggt tacggattag aaatcgtggt ttctaagcaa tagctaagag tgaacagtct
    41761 ttgatgttaa aagcttgttt agagcttgca ttgtcagtta gaggtgtcaa ctgttcaggg
    41821 gttaacaata gactcagttg gctcttacca gctgagtttt ttatgcttca atgaggaaat
    41881 aatcgttatg gacaatagac caattggttt tttagattct ggtgtaggag gcttaactgt
    41941 tgttagtgag ctgatgcgtc agcttcccca tgaaaaaatc atttatattg gtgattcagc
    42001 aagagctcct tatggtccta gacctgctga acaaatcaga gaatatacct gggagttggt
    42061 tcgtttttta ttaacgaaac atgtcaagat gattgtcttt gcttgtaaca ctgcaacagc
    42121 tgttgcttgg gaggaggtca aggaggcttt ggatattcct gttttgggcg ttatcctgcc
    42181 gggcgctagc gcagctatca aggctactag tggaggaaag gttggtgtta ttggcacatc
    42241 aatgactatt tcttcaggca tttaccagga aaagatccag ttgctggctc ccactgttca
    42301 ggtaactagc ctagcctgtc ctagatttgt tcctattgtg gagtccaatg agataagctc
    42361 aagtgtggcc aagaaaattg tctatgaaac cttggctccc ttagttggaa agatagatac
    42421 ccttgttttg ggctgcaccc attatcctct tcttaggacg attatccaaa atgtgctggg
    42481 accacaggtt aaattgattg atagtggggc agagtgtgtg cgtgatattt ctgttctttt
    42541 aaattatttt gagattaatg gcagtcgaga tgatgaacat aggcgtcatc atttttacac
    42601 tacagccggc tcagacagct ttcaagcaat tgcctcagcc tggctaaatc aaacgataga
    42661 tgtggagcat gtgaccttat gagtgataac atttatgaat acaaggataa agacaattgg
    42721 tttattggca agatgacagg ccataattta atggctggct ggggggttaa ccatgagctt
    42781 attgccaaaa tagacgatat gttaggtgcg attgctggtg atgtggattg ggaaagtccg
    42841 gtcggttatg atgtgactgt tattcgttac gcctcccctt ttgccttgat tagctttgtt
    42901 gttggcatga tcaatcagaa agccaatcga gcccttaagg ttgttcggca ctcaggtgcg
    42961 attttagtga ccgaaaacga gcgattgctt gctgtgcata tgccagatga tggcgtccct
    43021 gtggctgact tctttggtca acaggcagat ggctttgggg atacgatttt gattgcgact
    43081 cgaaatgaag gcaagaccaa ggaatttcgc cggctttttg gtgatatggg atatcgcgtt
    43141 gaaaatctca atgattaccc agagcttcca gatgtggcag aaaccggggt cacctttgag
    43201 gaaaatgccc gcctaaaagc agaaaccatt tcaaggctta ctggaaagat ggttctggca
    43261 gatgattcag ggctcaaggt ggatatttta ggtggcttac ctggggtctg gtcagctcgt
    43321 ttttcgggcc ctgatgctac tgatgagact aataatgcta agctattgca tgagctggca
    43381 atggtatttg atcaaaagga tcgctctgct caatttcata cgaccttggt ggttgctgca
    43441 cctggtaaag acagcttggt tgtcgaggct gattggcatg gctatattgc aaccaagcca
    43501 aaaggcgagc atggctttgg ctatgatccc ttgtttatcg ttggggagac tggacgtcat
    43561 gcagcagagc tagctgctga tgaaaaaaac aagctgtctc ataggggaca ggcggtcaag
    43621 aggttaatgg aggtatttcc agcatggcaa gcaaaacaat cattgtgatg agcgattcgc
    43681 atggcgatcg tgaggttgtg gcagctatta aaggccgtta ccttggaaag gttgatgcca
    43741 ttttccataa tggcgattct gagctagaaa gctcagatcc tatttgggag gggattcatg
    43801 ttgtggcagg caactgtgac catgatagcg gctataagga tagcctagtc acctcctttg
    43861 atggcttgac tattgctcaa acacatgggc atttgtatca tattaacttt acttgggata
    43921 ggctagatta ttttgctcag gagactggag cggatatttg tttgtatggg cacttgcaca
    43981 gacctgctgc ttggcaattg ggcaagactg tctttatcaa tcctggctcg gtcgctcagc
    44041 cgcgtggtga ggtgaatgaa aagctgtacg cgcgtgttga atggacagca gcttgcatta
    44101 gggtggatta ctttacctgt cagcataagt cttacccatc actttctaag gaatttaaac
    44161 gatgatagca aaagaatttg aagccttttt aatcagtcat ttggatagct acctgattcc
    44221 agcagaggag ctagccattt ttatcaacac gcataatgct gatcatgtca tgctcttatt
    44281 ggttagcaat ggtttttcac gagttcctgt cattaccaag gaaaagcaat atgtcggaac
    44341 gatcagcatt tctgatataa tgacctatca agccaaaagg cagctaacag actgggagat
    44401 gacgcaaact aatattggcg acatggtcaa tacaaagatt gagaccatca atattacctc
    44461 tagcttgact gaaatcatgc ataaattggt tgattttccc tttttaccag ttgttaatga
    44521 tgacaatcga tttatcggta ttattacgcg taagtccatt ttgaaggcgg ttaatagcct
    44581 tttgcatgac ttcactgatg aatacacaat cacaaaaaaa tgatagcatt tattgaaccc
    44641 tttctagcaa gcaaatctct tgctaataac agccagcaat cctatcgcta tgatttaagg
    44701 cagttttgcc agcaggtcgg acagcgtatt aatcctgaaa ccctagccct ctatcagcaa
    44761 agcttgtctg gccttacggt agcagctaaa aagcgcaagc tttcaacggt caatcagttt
    44821 ttgtactatt tgtaccagca gaaggctttg acagactatt ttaaaatgga cgataggata
    44881 gaagcctctt tttctttgaa gccccagctg acaaggcttg acaccagcgc tttttatgct
    44941 gaaacagcct tcctaaaagg gcagctcatt gcgctgctga ttctggagct gggcttgacg
    45001 ccaagtgaga tagcagggct tcgtcttgct gattttgacc tgggtcttca ggtgctaagg
    45061 ttgcaatctc acagaggcat tcgtgtgatg accttatcaa aggccttgct gccatttttg
    45121 gaaaaggcaa cagaagctca gcagctctac ctctttgatc atgacgccaa gcccttttca
    45181 aggcaatggt tttttaacca gctcagagat tttttagaga gcattggctg tgcggagctt
    45241 tcagcccaga gtctgagaga gcaattcatt ttaaatgaaa aagcagccgg taaatccatc
    45301 attgaggtgg ctcagctgct ggggctaaaa agcccgatca ccttagaaaa atattataag
    45361 atgtaatgga tataaaagta aaagattttg aaggtcctct tgatttactc ttgcacctag
    45421 tgtcaaagta tgaggttgat gtttaccagg tgcctattgt ggaggtcatt gaacaatact
    45481 tggcctatat tgagaccctg caggcgatgc gcttggagct tgctggagag tacatgctga
    45541 tggctagtca gctgatgctc atcaaaagca gacgactgct gccaaagctg gtagacaagg
    45601 agcctgatga ggaggatctt gagcaagagc ttttgggtaa gattgaagaa tatagtcgtt
    45661 tcaaggctct gagtcaggag ttggccagcc agcatgacaa gagggctctg cttttttcca
    45721 agccaaagca ggagcttatc tttgagcagg ccgtcctaca aaaggataaa acagtcatgg
    45781 atttgttttt agctttttca cagttaatgg ctgcaaagca agaggccttt aaatataacc
    45841 atacggttat tgagcgagat gattatcgta ttgaggatat gatggagctt attgaagcta
    45901 ggcttgagct agagcaggag cttactttga cggatttatt gaagcattgt gatcatctca
    45961 atgaggccat taccttgttt ttagcaagcc tagaattaat caaacggcag cttgttggta
    46021 ttgagcagac atcacatttt ggccagattg ttttgcgaaa ggagatccaa tgacctattt
    46081 atctcagctg gaggccttgc tgtttgtcgc aggagaagaa ggactaagcc tacgtcagtt
    46141 ggccagccta ttagagttaa caccgacagc cttacagcag cagctcgaca agctttctca
    46201 gaaatacaaa gaggataagg aatctggcct gtgcttgatt gagtcctcta ggacctataa
    46261 gttagtcacc aaagagtgtc tggctccctt gcttaaagac tatgctaagg ctccaatcaa
    46321 ccaaaccttg tcacgagcaa gcctggaggt tttgtcaatt gttgcctata agcagccgat
    46381 tactcggatt gaaattgacg agattcgtgg tgtcaattca agtggtgccc ttagtaaatt
    46441 agtggccttt ggtttggttc aagaggctgg caaaaaggaa gtgattggtc gaccaaatct
    46501 ttatgcaaca acagattact ttcttgatta tatgggtatc aatcatttag aagagctggt
    46561 tgatatttct tctattgctg ttgaagagca agagacaacc ctgttttaaa ggcaaagagg
    46621 agcttgtctc atttgcagat aggccttatg ccctctacta gaagagataa cagtcctaac
    46681 aaggtatagt gcctgaaaat cctattgtcg ttatggacag cggtcttttt aggcatgcta
    46741 ttaataagag tagacctgtt taagctagtg agcttttacc cataggagag tgactggtct
    46801 gttggagcta tcatcagatt tcctaataag aaagagagaa ggataatgag aattaacaaa
    46861 tacatcgccc atgcaggcct tgctagccgt cgtaaggctg aagagctgat caagcgaggg
    46921 ctggtgaccc taaatggtca ggtgataaca gatttagcaa ctactgttaa atcaggcgac
    46981 cttgttgagg tagaggggat tcctatttac aatgaagaga aggtttatta tctcctcaac
    47041 aagcctcgtg gtgtcatctc aagcgtttca gatgataagg ggcgtcagac agtgattgat
    47101 ttgctgccgc aggttaagga gcgcatttac cctgttggtc gcttggactg ggatacctct
    47161 ggcttattaa ttttgaccaa tgatggtgat tttacagata aaatgattca cccccgtaat
    47221 gaaatcgaca aggtttatct ggctcgtgtc aagggagtgg taactaaaga aagcctgcgt
    47281 cccttaacac gtggtgtcgt tattgatggt aaaaaaacaa agccggctcg ttaccgcatt
    47341 attcgtgttg agcctgataa aaatcgctct attgttgaac taaccattca tgagggccgt
    47401 catcatcagg tcaagaaaat gtttgaagtg gttggacact tggttgataa gctatcaagg
    47461 acacagtttg gcagccttga tgtcagaggc ctaaagcccg gagaagccag aaggctgagc
    47521 aaaaaagaag tcagccagct acatcattta gcgagcacac gaaaatgatc aaagccctac
    47581 tcattgctcc tgtcagagcc tatcagaaat atatttctcc cttatttcct ccttcctgtc
    47641 gttatcagcc gacctgctcg gcctatatga ttacagctat tgaaaagcat ggtgctaagg
    47701 gtgttttgat gggacttacc agactattaa ggtgccaccc ttttgccgct ggcggagaag
    47761 acccggttcc agataccttt tccttaaaaa gacatttcat aacgcatgaa aaaatacagg
    47821 attttgacca aaaaactgat tgacaatagc agttaaagtg ctataatagc agttaagtat
    47881 tcgttggttt aaatcaaacc tgttatgatt taagttagcg agtcaccgtc aaccacattg
    47941 tttgctgagc atgactccgg gcagtgtggt ttttttgatg aaaagagtaa gcgggacaag
    48001 catgaaacaa gaaatcatta atagacaata tagggaaaaa gatagtcaaa accatgtggt
    48061 gctctttcag ccacaaattc cacaaaacac aggaaatatt gctaggacct gtgctgccac
    48121 caacacgcct ttacatatca tcaggcctat gggctttccg attgatgacc gtaagatgaa
    48181 aagagcgggg ctagattatt gggataagct agacattaga ttttatgatc atctagatga
    48241 atttttagca caatgtgatg ggagcttgca tgtgattagc aaatttgctg atagggtata
    48301 ctcagatgaa gcctacaatg atcgtcagtc tcattatttt ttgtttgggc gtgaggatac
    48361 tggtctgcct gagcccttta tgcgtcaata tgctgatagg gcactcagga ttcctatgaa
    48421 tgatgagcat gtcagaagtc tcaatgtctc taatgctgtt tgcatgatcg tctatgaggc
    48481 acttagacag caagccttta agggcttaga gcttagccat acctatgagc atgacaaact
    48541 aaaatcataa taagcatatc gcaaaacatc agttagattg aagaagtatc cgtaggggag
    48601 cttcttcagt ctttttttat tgtattcttt gcttattaac caagcagttg acacgaaaat
    48661 tccaatagat cgtttaaagc caataaaacc attattaggc ttgcattaca ggcaggtatc
    48721 aaagaaagat atagaaaaat ataccagaaa aaaatct
//
LOCUS       DARYJX010000014        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYJX010000014 DARYJX010000000
VERSION     DARYJX010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TU257_000770"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TU257_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL0833799.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TU257_000771"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TU257_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TU257_000772"
     CDS             1286..2599
                     /locus_tag="TU257_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0833800.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TU257_000773"
     CDS             2700..3587
                     /locus_tag="TU257_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0833801.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TU257_000774"
     CDS             3600..4430
                     /locus_tag="TU257_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0833802.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TU257_000775"
     CDS             4446..4901
                     /locus_tag="TU257_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL0833803.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TU257_000776"
     CDS             4926..5576
                     /locus_tag="TU257_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL0833804.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TU257_000777"
     CDS             5605..6525
                     /locus_tag="TU257_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL0833805.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TU257_000778"
     CDS             6540..7424
                     /locus_tag="TU257_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0833806.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TU257_000779"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TU257_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TU257_000780"
     CDS             complement(7738..8562)
                     /locus_tag="TU257_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL0833807.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TU257_000781"
     CDS             8791..9564
                     /locus_tag="TU257_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL0833808.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TU257_000782"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TU257_000782"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL0833809.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TU257_000783"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TU257_000783"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL0833810.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TU257_000784"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TU257_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL0833811.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TU257_000785"
     CDS             12390..13052
                     /locus_tag="TU257_000785"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL0833812.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TU257_000786"
     CDS             13045..13677
                     /locus_tag="TU257_000786"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL0833813.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TU257_000787"
     CDS             13679..14950
                     /locus_tag="TU257_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL0833814.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TU257_000788"
     CDS             14940..15878
                     /locus_tag="TU257_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL0833815.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TU257_000789"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TU257_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL0833816.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TU257_000790"
     CDS             16830..19334
                     /locus_tag="TU257_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL0833817.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TU257_000791"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TU257_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL0833818.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TU257_000792"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TU257_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL0833819.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TU257_000793"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TU257_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL0833820.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23059..23277
                     /locus_tag="TU257_000794"
     CDS             23059..23277
                     /locus_tag="TU257_000794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833821.1"
                     /translation="MDSIPAFLMCYNRWAVQQLIKAMTEKSSPIRHKRLGKGLKKALL
                     TTLSDTFGCPKKLFAVSILMEKQSFENG"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TU257_000795"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TU257_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL0833822.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAYL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TU257_000796"
     CDS             24977..25831
                     /locus_tag="TU257_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL0833823.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TU257_000797"
     CDS             26041..27237
                     /locus_tag="TU257_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL0833824.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYEAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TU257_000798"
     CDS             27660..28181
                     /locus_tag="TU257_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0833825.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TU257_000799"
     CDS             28257..28628
                     /locus_tag="TU257_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0833826.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TU257_000800"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TU257_000800"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL0833827.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TU257_000801"
     CDS             30244..31902
                     /locus_tag="TU257_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0833828.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TU257_000802"
     CDS             32071..32985
                     /locus_tag="TU257_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833829.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TU257_000803"
     CDS             32995..34026
                     /locus_tag="TU257_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833830.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TU257_000804"
     CDS             34038..35084
                     /locus_tag="TU257_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833831.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TU257_000805"
     CDS             35084..36019
                     /locus_tag="TU257_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0833832.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TU257_000806"
     CDS             complement(36648..38330)
                     /locus_tag="TU257_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0833833.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TU257_000807"
     CDS             complement(38332..38562)
                     /locus_tag="TU257_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL0833834.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TU257_000808"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TU257_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL0833835.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TU257_000809"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TU257_000809"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL0833836.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TU257_000810"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TU257_000810"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL0833837.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TU257_000811"
     CDS             41002..42030
                     /locus_tag="TU257_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL0833838.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU257_000812"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU257_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL0833839.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TU257_000813"
     CDS             complement(42888..44060)
                     /locus_tag="TU257_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0833840.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TU257_000814"
     CDS             44186..44716
                     /locus_tag="TU257_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL0833841.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TU257_000815"
     CDS             44761..45348
                     /locus_tag="TU257_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL0833842.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TU257_000816"
     CDS             45452..46174
                     /locus_tag="TU257_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0833843.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TU257_000817"
     CDS             complement(46216..46515)
                     /locus_tag="TU257_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL0833844.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TU257_000818"
     CDS             46913..47500
                     /locus_tag="TU257_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833845.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TU257_000819"
     CDS             47639..>48181
                     /locus_tag="TU257_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0833846.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13643 a         9419 c        11267 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct acaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcata tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctacg aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga caaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYJX010000015        44665 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYJX010000015 DARYJX010000000
VERSION     DARYJX010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44665
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            398..811
                     /locus_tag="TU257_000820"
     CDS             398..811
                     /locus_tag="TU257_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0833847.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TU257_000821"
     CDS             1071..1652
                     /locus_tag="TU257_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL0833848.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TU257_000822"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TU257_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TU257_000823"
     CDS             2457..4460
                     /locus_tag="TU257_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0833849.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TU257_000824"
     CDS             4457..5065
                     /locus_tag="TU257_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0833850.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TU257_000825"
     CDS             complement(5254..7980)
                     /locus_tag="TU257_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL0833851.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TU257_000826"
     CDS             complement(7995..9281)
                     /locus_tag="TU257_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL0833852.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TU257_000827"
     CDS             9414..10472
                     /locus_tag="TU257_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0833853.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TU257_000828"
     CDS             10487..12181
                     /locus_tag="TU257_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL0833854.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TU257_000829"
     CDS             12208..13599
                     /locus_tag="TU257_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0833855.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13586..13723
                     /locus_tag="TU257_000830"
     CDS             13586..13723
                     /locus_tag="TU257_000830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833856.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TU257_000831"
     CDS             complement(13919..16093)
                     /locus_tag="TU257_000831"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL0833857.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TU257_000832"
     CDS             complement(16081..16974)
                     /locus_tag="TU257_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0833858.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TU257_000833"
     CDS             17186..18136
                     /locus_tag="TU257_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0833859.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TU257_000834"
     CDS             18146..19072
                     /locus_tag="TU257_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0833860.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TU257_000835"
     CDS             19156..20601
                     /locus_tag="TU257_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0833861.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TU257_000836"
     CDS             20949..21554
                     /locus_tag="TU257_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL0833862.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TU257_000837"
     CDS             21544..23268
                     /locus_tag="TU257_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0833863.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TU257_000838"
     CDS             23268..24752
                     /locus_tag="TU257_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0833864.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TU257_000839"
     CDS             24766..28209
                     /locus_tag="TU257_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL0833865.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TU257_000840"
     CDS             28360..29244
                     /locus_tag="TU257_000840"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL0833866.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TU257_000841"
     CDS             29370..30143
                     /locus_tag="TU257_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL0833867.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TU257_000842"
     CDS             complement(30475..31557)
                     /locus_tag="TU257_000842"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL0833868.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TU257_000843"
     CDS             complement(31616..32371)
                     /locus_tag="TU257_000843"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL0833869.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TU257_000844"
     CDS             32809..32979
                     /locus_tag="TU257_000844"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833870.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            complement(33641..33799)
                     /locus_tag="TU257_000845"
     CDS             complement(33641..33799)
                     /locus_tag="TU257_000845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833871.1"
                     /translation="MACYSGRVKKLRQVAARSEWVVVPMGDSSTANKMEEAKKLAAFE
                     ATQTLFKL"
     gene            33886..33956
                     /locus_tag="TU257_000846"
     tRNA            33886..33956
                     /locus_tag="TU257_000846"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TU257_000847"
     CDS             34484..34738
                     /locus_tag="TU257_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL0833872.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TU257_000848"
     CDS             34760..35260
                     /locus_tag="TU257_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0833873.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TU257_000849"
     CDS             35520..36104
                     /locus_tag="TU257_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833874.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TU257_000850"
     CDS             36304..36867
                     /locus_tag="TU257_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0833875.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TU257_000851"
     CDS             36880..39531
                     /locus_tag="TU257_000851"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL0833876.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39744..40232
                     /locus_tag="TU257_000852"
     CDS             39744..40232
                     /locus_tag="TU257_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL0833877.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41235)
                     /locus_tag="TU257_000853"
     CDS             complement(40435..41235)
                     /locus_tag="TU257_000853"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833878.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
     gene            41746..41982
                     /locus_tag="TU257_000854"
     CDS             41746..41982
                     /locus_tag="TU257_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL0833879.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
     gene            41975..42673
                     /locus_tag="TU257_000855"
     CDS             41975..42673
                     /locus_tag="TU257_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL0833880.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            42873..43331
                     /locus_tag="TU257_000856"
                     /pseudo
     CDS             42873..43331
                     /locus_tag="TU257_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            43332..44306
                     /locus_tag="TU257_000857"
     CDS             43332..44306
                     /locus_tag="TU257_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0833881.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
BASE COUNT        12281 a         8909 c        10444 g        13031 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttggaaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatca gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttta aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctat acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcatttttt cttcctaacc tccattactt atgtttattt aataatagct
    41281 agggttagta taaatgagat gttgtgtaag gtaaagatgt ttattaaaag tgactaaaag
    41341 taaagaaata atcctaatag tagtttgggg atattttgat ttatacaaaa aataatgtca
    41401 ttgaacacgc tttatctaaa atagtctaac attctaacga aaataattcc aattattttc
    41461 atatactggc tagacatgct gtattagctt aatcaagaat tacagccgca gttttaaaga
    41521 cactcaggtt agtgtattat aaaaagctgg tgtgggttac aaaggatttc atatcactta
    41581 gattatgtca taattagtta agatgatgaa tccttatcta aaaacaaagc aaacttgtac
    41641 gtttgcgact ttcgtgatct ttaagcttac aaaagctgag taaattggta taatgatcat
    41701 taaaagagct catgctatga tgtagaccta taaaaggaga aaaccatgac atttgaagag
    41761 attttgccag gcttgaaggc caagaaaaaa tacgttcgta agggctgggg aggcgctgaa
    41821 aactatgttc agctgtttga tagcattgaa caaaatggtg tggcacttga ggtgacgcct
    41881 tactttttga ttaacgtgtc aggagctggc gagggctttt ccatgtgggc accgactccc
    41941 tgcgacgttc ttgctactga ctgggtagag gtctatgact aagcgggtgc tgatcactgg
    42001 tgtgtcatcg ggcataggac tggcacaggc gcgcctgttt ttgagaaatg gctttactgt
    42061 ttatggggtt gacaaggcaa aaaagcctga tttatcagga gattttcagt ttttacagtt
    42121 agatattaca ggtgatttag ctgagctttt tgaggctgtg cctagggttg atgtgttgtg
    42181 tcatactgcg ggcgttcttg atgcctataa gcccttgctt gataccacac aggctgattt
    42241 tgaggctctc tttcaggtca atttctttgc agctgtccgc atcacgcgtc actatttggc
    42301 acagatgctg acagctcaat caggtattat catcaatatg tgctctattg ctagcttcat
    42361 ggcaggtggc ggcggagctg cctatacctc cagcaagcat gctctggctg gttttaccag
    42421 acagctagcg cttgattatg ccaaggcagg cattcaggtt tttggcattg cccctggcgc
    42481 agtgcaaaca gcaatgacag ccacagactt tgagccaggt ggcttagccc agtgggtggc
    42541 tgatgagact cctatcggtc gttggcttag ggctgaagaa atagccgagc tgaccatgtt
    42601 tttggcatct ggaaaagcta gcgccatgca gggagaaatt gttaaaattg atggcggttg
    42661 gagcttaaag tgaaacagca catcgacata aggcctagca agatctggct tgtctgtaca
    42721 gagggtgaca gttgatagct gtatcaagca atcttgtcac aggctaagag ggagctgatg
    42781 aagttttttc catgaagcct agtgcctagt aggtttgctt aatacagcag gagcctacct
    42841 gtctagagga ttcgatcaat agaggtgata acatgactgc agaagaatta tggtctcaat
    42901 accagcaaat caatcctggt gttggtgatc tagctgaggc ctgggccttt ggagctgagc
    42961 ctgatttatt agcgcaatta gtgctagaag gcactaaaac agctacagcc tctgcctatg
    43021 actgatatga gcctgatcat gagccgcttt ccaaagaggg cagctatgac gtgattttgg
    43081 atagtaggga tcaggcgatc tgtattatcc agattactaa ggttagtctt gttcccttca
    43141 aggacgtgcc agcagagcat gcctataagg aaggagaggg tgataaaagc ttggaagaat
    43201 ggcggctgct tcatgaggcc tttttcagac cttattttga agaggtaggc ttacgcttta
    43261 ccgaggatag ccttattgtg ttagaggagt ttcagagggt ttaccctgaa gctgctaaaa
    43321 aggagaaata aatgaaatta gcccttgttg gtacaggcat gattgtcaaa gaggttttgc
    43381 ctgttttaaa ggagatcaaa agcatagact taatggcgat tgtttcaacg cctcgtagtc
    43441 ttgaaaccgc agaggcgctt gctgacgcct ttggcattca acaggccagc tgtcagctag
    43501 ccgaggtcct aaaaaatgaa gaggtggata cggtttatgt tgccacccca aatcatttgc
    43561 attttgaagt ggctaagcaa gcccttgagg ctggtaagca tgtcatttgt gaaaagccat
    43621 ttaccatgac agccaaggag cttgatgctt taagcagcat tgcaagagct aagcagctga
    43681 tattattaga agctattacc aaccaatatt tgccaaacac ccaatttatt aaggatcact
    43741 tgactgagtt aggagagatt aagcttgtgg agtgcaatta ttctcaatat tcctctcgtt
    43801 atgatgcctt taagcgtggg gagattgcac cagcctttga tcctaaaaag ggtggagggg
    43861 ccttgcgtga tttgaatatt tataatatcc atctgctcgt tggcttattt ggcaagcccc
    43921 aaacggttca gtacctagct aatatggagc ggcaggttga cacctctggt gttttgctga
    43981 tggattatga gcgatttaag gctgtttgta ttggggctaa ggattgcagt gcagagattg
    44041 tctctacgat tcaggggaat aaaggctttc tttctgtttt aggtgctcct aatgctgtac
    44101 cagagctttt actagccatt cgaggtgagc aagcaaggac cgtcaacttt aaccacccgt
    44161 ctcatcgcat gtacgatgaa tttattgcct tttcagatat tatctctaat aaggacatgg
    44221 aaagggcaga gcaggccttg gagcacagca aggcagtcat ggctgtttta gagcaggcag
    44281 cagcttcgct agaaagcgat agctaagagt agctagtggc tacaagctaa gtcatctttt
    44341 ttgctagctg tcttaagaag tgatgaccct tcttgttcta tcagatacag gtcttgttcc
    44401 tgatgactcg gagtctttca atcgcggagc ctaactgctt ttttcatagt gaggggtcta
    44461 atttgcagct tgctttgttt acgacatctt tgatacttag cgatgacagg cagctctagc
    44521 tagctgcttt aaaaaaggag tcaaggtagg taagggagtt tgtctgaagc taaggactat
    44581 tgcagcattc ttgttttttc tgcaaattaa ggccatttgt gctataatga gatgatctat
    44641 gtacaaacgg aggaagtcat tatgc
//
LOCUS       DARYJX010000016        43743 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYJX010000016 DARYJX010000000
VERSION     DARYJX010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43743
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(19..1290)
                     /locus_tag="TU257_000858"
     CDS             complement(19..1290)
                     /locus_tag="TU257_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL0833882.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TU257_000859"
     CDS             complement(1283..1891)
                     /locus_tag="TU257_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL0833883.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TU257_000860"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TU257_000860"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL0833884.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TU257_000861"
     CDS             3817..4287
                     /locus_tag="TU257_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL0833885.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TU257_000862"
     CDS             4289..4633
                     /locus_tag="TU257_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL0833886.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TU257_000863"
     CDS             4650..5078
                     /locus_tag="TU257_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0833887.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TU257_000864"
     CDS             complement(5276..7813)
                     /locus_tag="TU257_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0833888.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            7958..8131
                     /locus_tag="TU257_000865"
     CDS             7958..8131
                     /locus_tag="TU257_000865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833889.1"
                     /translation="MKGFLAISKAWSFNRRISYWFFWIYEKELLFFDVAGIKYGKIGS
                     IKSLSTFRLAEIC"
     gene            8376..9329
                     /locus_tag="TU257_000866"
     CDS             8376..9329
                     /locus_tag="TU257_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL0833890.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TU257_000867"
     CDS             9329..10075
                     /locus_tag="TU257_000867"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL0833891.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TU257_000868"
     CDS             10324..11328
                     /locus_tag="TU257_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0833892.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TU257_000869"
     CDS             11625..13811
                     /locus_tag="TU257_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0833893.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TU257_000870"
     CDS             13889..14710
                     /locus_tag="TU257_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0833894.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVPLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TU257_000871"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TU257_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0833895.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TU257_000872"
     CDS             complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TU257_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL0833896.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYSYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIITFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17294..18898
                     /locus_tag="TU257_000873"
     CDS             17294..18898
                     /locus_tag="TU257_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0833897.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLNDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGKDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDSYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19121..21340
                     /locus_tag="TU257_000874"
     CDS             19121..21340
                     /locus_tag="TU257_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL0833898.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21355..21798
                     /locus_tag="TU257_000875"
     CDS             21355..21798
                     /locus_tag="TU257_000875"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL0833899.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21925..23217)
                     /locus_tag="TU257_000876"
     CDS             complement(21925..23217)
                     /locus_tag="TU257_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL0833900.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23501..23677
                     /locus_tag="TU257_000877"
     CDS             23501..23677
                     /locus_tag="TU257_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833901.1"
                     /translation="MTRISILLFKGYVSYDKRDQAIGKSSVLKGFEALALNLSSGVSM
                     KMTWALYQIRMKSN"
     gene            23972..24820
                     /locus_tag="TU257_000878"
     CDS             23972..24820
                     /locus_tag="TU257_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL0833902.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24970..26103
                     /gene="ugpC"
                     /locus_tag="TU257_000879"
     CDS             24970..26103
                     /gene="ugpC"
                     /locus_tag="TU257_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL0833903.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26287..27906
                     /locus_tag="TU257_000880"
     CDS             26287..27906
                     /locus_tag="TU257_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL0833904.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28015..28377
                     /gene="traF"
                     /locus_tag="TU257_000881"
                     /pseudo
     CDS             28015..28377
                     /gene="traF"
                     /locus_tag="TU257_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28491..28850
                     /gene="yajC"
                     /locus_tag="TU257_000882"
     CDS             28491..28850
                     /gene="yajC"
                     /locus_tag="TU257_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL0833905.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29024..29773
                     /locus_tag="TU257_000883"
     CDS             29024..29773
                     /locus_tag="TU257_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL0833906.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29783..30577
                     /locus_tag="TU257_000884"
     CDS             29783..30577
                     /locus_tag="TU257_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL0833907.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30609..31874
                     /gene="rseP"
                     /locus_tag="TU257_000885"
     CDS             30609..31874
                     /gene="rseP"
                     /locus_tag="TU257_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL0833908.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32144..34000
                     /locus_tag="TU257_000886"
     CDS             32144..34000
                     /locus_tag="TU257_000886"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL0833909.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34052..34609
                     /locus_tag="TU257_000887"
     CDS             34052..34609
                     /locus_tag="TU257_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL0833910.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34944..39341
                     /locus_tag="TU257_000888"
     CDS             34944..39341
                     /locus_tag="TU257_000888"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL0833911.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39463..39891
                     /locus_tag="TU257_000889"
     CDS             39463..39891
                     /locus_tag="TU257_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0833912.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40021..40566
                     /locus_tag="TU257_000890"
     CDS             40021..40566
                     /locus_tag="TU257_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0833913.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40745..41359)
                     /locus_tag="TU257_000891"
     CDS             complement(40745..41359)
                     /locus_tag="TU257_000891"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0833914.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41724..43151
                     /locus_tag="TU257_000892"
     CDS             41724..43151
                     /locus_tag="TU257_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0833915.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43417..43686
                     /gene="rpsO"
                     /locus_tag="TU257_000893"
     CDS             43417..43686
                     /gene="rpsO"
                     /locus_tag="TU257_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL0833916.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT        12328 a         8698 c        10414 g        12303 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaagctt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gccattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tggaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggta atgatagaat
    16381 aatttttttc agagcgcagc gtatcaccac tcaccacagg gataaaggta tttcgtagac
    16441 tgaagatgat ttccttgagc ttgtgcacat caccctcttg aacaatgcta gataaatttt
    16501 tctcataact gtagagacaa accttagatt cctgcttctt gacaaacata ttggcctttt
    16561 gcacctcgat attgtcggaa aaatccctaa tatagtgacg taaaggaggt gataacaaat
    16621 cctctatctt gccggaaaag aagtaatgga ccacaatcaa gaggtcacga atagcattca
    16681 aaggataaac aggtaaatgc tttagcgctt ggtaaagaat ctcttcttct tccttagtca
    16741 aatccttatc agcaacggcc accttaaaaa aggtcttatc caaaacatta cagcgccaag
    16801 ggccaattaa aatataatga tcctgataac ggtatattaa aaaaagctca ttatagcttc
    16861 cctgaaagaa aagattggtt gcctgttcct tgtccatttg cctaagcact gcttgaaaac
    16921 gataataaaa ttcaaaggta tcatcattcc aaaagctttc tgtcacctga tggtccttat
    16981 caaatactgt aattgataac ttcaaacagc cctgtagaga ttttactaac gacatagtat
    17041 ccatgctaag cgtcaccccc ttcataatcc tcacggtatc ttattctatc ttaaaattta
    17101 agaaaagcaa ggatatgcac ttataatgaa aaaatagaca taaaaaacaa taatatacat
    17161 tcttgcttat taaataaaaa tgacaatgta ctgcataaag aagttcctgt cattaaaata
    17221 aaagtgccat gaggttataa tagtatggta aaacaaaaaa gtgtgcccat aacgggtaga
    17281 gaggaattga catatgtttt tgagaaataa caagcaaaaa tttagcatca gaaaactaag
    17341 tgccggtgca gcatcagtat tagttgcaac aagtgtgttg ggagggacaa ctgtaaaagc
    17401 gaactctgag gttagtcgta cggcgactcc aagattatcg cgtgatttaa aaaatagatt
    17461 aaacgatata gccataagta gagatgcctc atcagcccaa aaagttcgaa atcttctaaa
    17521 aggcgcctct gttggggatt tacaggcatt attgagaggt cttgattcag caagggctgc
    17581 gtatggtaaa gatgattatt acaatttatt gatgcacctt tcatcgatgt taaatgataa
    17641 acctgatggg gatagaagac aattaagttt ggcttcatta cttgtagatg aaattgaaaa
    17701 gcggattgct gatggagata gttatgcaaa acttcttgag gctaaacttg cagctattaa
    17761 atctcaacaa gaaatgctta gagaaagaga ttcccaactt cgaaatctag agaaggaaaa
    17821 agaacaagaa ctacaaaaag ctaaagatga gcgtcaagct cttaccgaat cattcaacaa
    17881 aactttatca agatcaacaa aagagtataa taaactaaaa acagaacttg caaaagaaaa
    17941 agaaaaagca gctaagatga ctaaggaatt agcagataag ctaagcaatg ctgaagcaag
    18001 tcgtgataaa gcctttgcag tatcaaaaga tttagcagat aaactaagta gtgctgaagc
    18061 aagtcgtgat aaagcttttg cagtatcaaa agatttagca gataaattgg cagctaaaac
    18121 agcagaagct gaaaagttaa tggaaaacgt tggtagtcta gaccgcttgg tagagtctgc
    18181 aaaacgtgaa atggctcaaa aattagcaga aattgatcaa ttaactgctg ataaggctaa
    18241 ggctgatgca gagcttgcag ctgcaaatga caccattgca tcacttcaaa cagagctaga
    18301 aaaagctaag acagagcttg ctgtttcaga gcgtttgatt gaatcaggca aacgtgaaat
    18361 tgctgagcta caaaaacaaa aagatgcttc tgataaggct ttagtagaat cacaagctaa
    18421 tgtagcagag cttgaaaaac aaaaagcagc atcagatgct aaggtagcag agcttgaaaa
    18481 agaagttgaa gctgctaaag ctgaggttgc agatcttaaa gcacaattag ctaagaaaga
    18541 agaagagctt gaagccgtta agaaggaaaa agaagcgctt gaagctaaga ttgaagagct
    18601 caaaaaagct catgctgagg aactttcaaa acttaaagaa atgcttgaga agaaagacca
    18661 tgcaaatgca gatcttcaag cagaaatcaa tcgcttgaag caagagctag ctgacaggat
    18721 taagtcattg tcacaaggtg gtcgtgcttc acaaacaaac ccaggcacta caactgctaa
    18781 agcaggtcaa ttgccatcta ctggtgagtc tgctaaccca ttcttcacta ttgcagctct
    18841 tactgtcatc gctggtgctg gtatggctgt ggtgtctcct aaacgcaaag aaaactaagc
    18901 tatttcctct ttccccaatg gacaatagcc gaaataatag agcgactatc gttctaacac
    18961 aaaagcaaca gtctcctgtc tgttgctttt tgtgatatta gggctcatca gtctaggcta
    19021 atggttttct gcgctttatc tgcagctttg aggattcctt cttttgcttt tacagtgaaa
    19081 gtgttaaaat aggaaaaaca actagtaatt gaggaagtaa atggttaaag aaatcaattt
    19141 atcaggagag gaagtagttg cccttgctgc caagtacatg acagacggtg acgtcgagct
    19201 tgtgcaaaag gcgcttgatt atgcgacagc tgctcatttt taccaggtta gaaagtcggg
    19261 ggagccttat attgtgcacc ctattcaggt agcagcaatc ctagcagacc tgcatttgga
    19321 cgctgtgaca gttgtctgtg gctttttgca tgatgtggta gaggatactg atattactct
    19381 agaggacatt gagtttgact ttggtaagga cgttcgtgac attgttgatg gggtcacaaa
    19441 gcttggtaag gtagaataca agtctcacga ggagcagctg gctgaaaacc accgcaaaat
    19501 gctcatggcc atgtcaaagg acattcgtgt gattttggtc aagctagccg accgactgca
    19561 caatatgcgc accctcaagc acctccgtaa ggacaagcag gagcggattt ctcgtgaaac
    19621 catggaaatc tatgccccgc tagcccatcg cttggggatc agtcggatca agtgggagct
    19681 ggaggatcta gcttttcgct acctcaatga gatcgaattc tacaaaatct ctcatatgat
    19741 gagagaaaag cggcgggagc gcgaagcttt ggttgatgat attgtcacta agattaaagc
    19801 ctacaccacc gatcaagggc tttatggtga tgtctatggc cgtcctaagc acatctactc
    19861 ggtttaccgg aaaatgcgtg acaagaaaaa gcgctttgat cagatatttg acttgattgc
    19921 gatccgttgt gtcatggaga cacaaagtga tgtttacgcg atggtcggct atattcatga
    19981 gctctggcgt cccatgcctg gccgcttcaa ggactacatt gcagcgccta agaccaatgg
    20041 ctatcagtcg attcacacga ctgtttacgg gccaaaagga ccgattgaaa ttcagattcg
    20101 gaccaaggaa atgcatcagg tcgctgagta tggggtagca gcccactggg cctacaaaaa
    20161 aggtattcgt ggcaaggtca atcaagtcga gcaaaaggtt ggtatgaatt ggattaagga
    20221 gcttgtcgag cttcaggctg cctcaaatgg cgatgctaag ggctttgttg actcggtgaa
    20281 ggaggacatc ttttcagagc gtatctatgt gttcacaccg acaggagcag tgcaggaatt
    20341 gcccaaggat tcaggcccta tagactttgc ctatgccgtt cacactcagg ttggtgaaaa
    20401 ggcgacagga gccaaggtca atggccgcat ggtgcccttg acagccaagt taaaaaccgg
    20461 tgatgtggtg gaaattgtca ccaatccgaa ttcctttggt cctagtcgtg actggattaa
    20521 gctcgtcaag accaataagg ctcgtaacaa gattcgccaa ttctttaaaa atcaggacaa
    20581 ggagctgtct atcaataaag gacgtgagct tctggttagt tattttcaag agcagggcta
    20641 tgttgccaac aagtaccttg agcgtaagcg tattgaggag attttaccaa aggtcagtgt
    20701 taaaagcgag gagtctctct atgccgctgt tggctttggc gatattagcc cagtcagtgt
    20761 ctttaataaa ttaaccgaaa gagaaaggcg tgaggaggag cgtgccaagg ctaaggctga
    20821 agctgaggag ctggttaagg gcggtgaggt caagcatgaa aacaaagaga ttctcaaggt
    20881 ccgcagtgaa aatggcgtga ttatccaagg ggcgtctggg cttctcatgc gtatcgccaa
    20941 atgctgcaat cccgtaccag gagatgtgat tgaaggctat attaccaagg gacgaggcat
    21001 tgctattcac cgcgcagact gtaataacat caagagtcag gacggctatc aggagcgtct
    21061 cattgaggtt gagtgggatt tggagcattc tagcaaggat taccaagctg agattgatat
    21121 ttatggttta aatcgtatcg gcctgctcaa tgatgtcctg caaatcctat ctaacgccac
    21181 caagagcatt tcaactgtca atgcccagcc gaccaaggac atgaagtttg ccaatattca
    21241 tgtgagcttt ggcattccta atctggctca gctgacagct gttgttgaaa aggtcaaggc
    21301 ggttccagat gtttacagcg tcaaacgaac caacggataa aaaggagacc aaccatgaaa
    21361 attgtgattc agcgcgtcaa ggaagcctca gtgtcgattg atgggaaaat agctggcgct
    21421 attgatcaag ggctgctgct gcttgttggc ataggtccag atgatcaggc agaggatata
    21481 gactatgcag tgcgtaaaat cagtcatatg cggatttttt cagaccccga gggcaagatg
    21541 aaccgatcca ttcaggacat tgagggcagt gtcttgtcta tctcgcagtt tacgctatat
    21601 gctgacacca aaaagggcaa ccgacctgcc ttcaccgggg ctgctaagcc tgacagggcc
    21661 agccagcttt ataacagctt caacgctcag ctagagcagc ttgtaccggt tcagcgaggg
    21721 gtctttggtg cggacatgca ggttagtctg atcaatgatg gcccagttac gattatccta
    21781 gatacgaagt atcgataact gcctagcgat cgatcgtttg cttaggagag tcatataaag
    21841 gaaaaacaaa aagacgagtg gtatgagaag cactcgtctt tgtcgtttat gctgctgtgt
    21901 tgaagctagc tagggctact agtcttattt ttgcaggtct ttgtagactg cgatgaattc
    21961 tgtctcagaa attggggtta agctgccagt gaattggtaa gaagtaccat ttttagcttg
    22021 gaaagtatta ggtaaacctt taaggtattt gtcgatagtc tcagtggtaa ttgcttcgtg
    22081 tgttttaaag gtgtattcgt taatcagctg ctgctgtttg tcctgttggt aaatagtaac
    22141 tgaacgatag gttgtgctat agtcatcgtt aatatcctta gaaataaaat aggtttctac
    22201 aacagaatct gaatgtgtcg catagctaat gggattgttg acgtcatact ttgaattata
    22261 tacttgagct atcctgttag aatctatgat atagttaaag tcctcatcgc gatcagcatg
    22321 gtagaccatg cgttcactag ctccactgta aatctcaccg ttatggcttt gatgagttat
    22381 atcaggatcc tgcgtgactg ttgtactgat tcgcttgacg agctgatacc cgtctttgaa
    22441 agcctgagtg gtttcaaaag cctttttagc agcttcaaag agctcctcag aagagaccct
    22501 gctgccatag tatcttaacc cggtaagtcc ttctttacca aggctgtcag ttacatcaac
    22561 attaacaagc tgcccattgt cttttttgag gaatttaacg tgctgtgtca cagctacggc
    22621 atctgaatct tggattgggt ttcctgcctt atctgttacc ttaatgtcct tgagagctac
    22681 cttgctaact ttttccacaa ggacctgacc cgtcaagatg tatgtttggt ctttttgatg
    22741 atactgtcct ttgattggtg tcgtaaaatg gtctgtgcta agtatttcag ctgtagaagc
    22801 ttttgttaat ttggcatttt tcaaactaat gaccttaaag ctttctgctg aaggatctat
    22861 gacgtcttga actagcttta tcatctcatt tgtggtgtag gttttgccat attctagtct
    22921 aatatcctga taatgtggag atacgatggt gtgattagtg ttatctactc cagtgatatt
    22981 gaccatgagg tacagtcctg tggtttcttg atagtctttt gaatggattg gcttagtggt
    23041 gtcctcgtat ttatagtgat ttgctaccct actagagctt gaccatgccc acccaacttt
    23101 gtaatggttt gctttaacgg caggtgctcc caaggtcatg gtgaatagtc caatgactac
    23161 agttcctatt tctaaaggtg ttttcccaag gtgatacagt ctttttgaag tcaacatatt
    23221 tcaaacctcc ctaaatcctg tcagtctcta tagttataaa aatacagaga atcgttagaa
    23281 gaattaatgt ttcatgccgg caagatgagt gtaacaaaag attggtgccg atacaagaag
    23341 atggagatta gagcatctgg tttcaatgag agttacataa tagcagaagg ttttttcact
    23401 atgagagcta atcgtcttaa aatggtataa tagcaagtga ataggctatc taactggttt
    23461 aacagccatt tttagagaag cttaatagta ttgctgataa gtgactcgta tctccatatt
    23521 gcttttcaaa ggctatgtta gctatgataa gcgtgaccag gctatcggaa aatccagtgt
    23581 tcttaaaggc tttgaagctc tggctttgaa ccttagctct ggtgtttcta tgaaaatgac
    23641 ttgggccttg taccagataa gaatgaagtc aaattgaggt tttttgacaa aatgtttgag
    23701 taaatacaag ttcatagaag tctaatgtat aaaaatacaa ttgtatcgcc ataatctgaa
    23761 tgaccaaacc attaaaaaaa taaaattttt aaacattttg gaaaacgctt tcaaaactaa
    23821 aaagaactgt cctatagtca ttgcttagca ttaaagcaag gtgtgaaatg ttatcatatg
    23881 gagaaatagg ctgtcttgtg ctgtatctgt gccaaaaaag aatgcttgtt tttgtgatat
    23941 aatgtgacta agaaacctga aaggaatgct tatggcatta aaagactatt ttcctgatat
    24001 gcaagagggt gcatttcctc tggctgacca agattggatt agcgttgagg ttggggagca
    24061 gtacctccat ttccccaaat ccagcttgtc agagcgagag cagcttttgc ttggtttggg
    24121 gcggcagcgc aaagagccgt ccaaggatca gaaatctcct tggtatcatt atttgattct
    24181 gggccaaggg gagcagccgg aggagtttca gggttgccag ttcatctata tcaaccatca
    24241 atgtccttta gcaggtgatt tgattgagct tctaaagggg atcatagagg gagttgaggc
    24301 tgttttgccc attagccaga ccaggacagc ttttttggtc tgtcaccata gccgttcaga
    24361 cctttttcag ctcttagcaa atttattgcc cacgattgag agcgattttg gtttggcctt
    24421 gatgattttt atcggtaatg gctggtatca ggtgtcagga aatgccttga gagactattt
    24481 taaggaagaa aatgctgtgt ttacagctta tcttgctgag cactctgcca gtcgcttgct
    24541 gaccttttca gaggtcatgc tctggtcact cttagcaaac agtggtttgc cagccttgtc
    24601 aaagcatttt agtcagctgc ttttagccaa taaagaggtc atggatctgg tgctcgccat
    24661 gtggcaggag catggcaacc tggtacagac agcccagcgc ttgtatattc atcgcaattc
    24721 gctgcaatat aagctggata agtttgctca gcagtcaggt ctctatttaa agcagctaga
    24781 tgacttggcc tttgcttatc tatttatact gaagcattag atttgtgcag ggtgcccaaa
    24841 gacatttggg cgttttgtct atatgatgaa aacgctatct ttgctataat aaaagcatca
    24901 aataaaaagt gtcagggttg ctagcattgc agtcagctag cagcctatct gacccattag
    24961 gagtaacgca tggttgaatt aaacttaaag cacatctata agaaataccc aaataccaca
    25021 cactatgctg ttgaggattt cgatttagac attaaggata aggaatttat cgtttttgta
    25081 gggccttcag gctgtggtaa gtcaacaacg cttcgtatga ttgctgggct tgaggatatt
    25141 tcagagggtg aattgaaaat tgacggtgag gttgtgaatg acaaatcacc aaaggaccgc
    25201 gatatcgcga tggttttcca aaactatgcc ctttacccgc atatgaccgt ttatgacaac
    25261 atggcctttg gtctcaagct acgtaaatac aaaaaagatg atattgatcg tcgtgtcaag
    25321 gaagcagcag aaatccttgg cttgacagaa tttttagaac gtaagccagc agacctttct
    25381 ggtggtcagc gtcagcgtgt ggctatggga cgtgctatcg tgcgtgatgc caaggtattc
    25441 ttgatggacg agcctttgtc aaacctagac gctaagctgc gggtgtcaat gcgtgctgaa
    25501 attgcgaaaa ttcaccgccg tatcggctca acaacaatct acgtaacgca cgaccagacc
    25561 gaagcgatga ccttggcaga tcgtatcgtt atcatgagtg ccactaaaaa ccctcaaggc
    25621 aacggtacaa tcggaaagat tgagcaggtt ggctcaccac aggagctcta taacctaccg
    25681 gccaataaat ttgttgcagg ctttattgga agccctgcga tgaacttctt tgaggtggtt
    25741 gtcaaggacg gtcagatcat cagtgaggac gggcttgata ttgctattcc agaaggtcag
    25801 gctaaaatgc ttgaagcagc tggctataag ggcaagaagg ttatttttgg tatccgtcca
    25861 gaagatattt caagcaacca aatcgtgcat gacacctatc caaatgccaa tgtcacagca
    25921 gaggtcttgg tttctgagct gcttggatct gaaaccatgc tttatgttaa gcttggtcaa
    25981 acagagtttg cttcacgagt tgatgcgcgt gacttccaca atccaggtga aaaggttagc
    26041 ttgaccttca atgttgctaa ggggcatttc tttgatctag aaacagagca agctattcgc
    26101 taataacacc tcctagaata aaatcctcat cttgcttgag gattttttaa caaaagaaaa
    26161 tgcaagcgat tgcgctatca aaaagaaaaa gggatttatc ataaagacaa cagatgttct
    26221 gtagtgctag gcgatcataa tgatggcacg aaatagcagg agactgttta gtaataagga
    26281 gatatgatgg aaaaacactg gtggcataaa gcgacaattt atcaaattta cccaaggtcc
    26341 ttcatggata caagtgggaa tggtattggt gatttaaaag gaatcacagg taagctggat
    26401 tatctacagg agctagggat cacagctatt tggctgtctc cagtttatca atcaccaatg
    26461 gacgataacg gctatgatat ttcagactat caggccattg cagctatttt tggtgatatg
    26521 gctgatatgg acgagctgct tgatgaggcc aagcagcggg ggatcaaaat catcatggat
    26581 ttggttgtca atcacacctc tgatgagcac gcttggtttg tggaggcaag agaaaatcct
    26641 gacagtccta aacgagatta ttacatttgg cgtgatcagc ctaataatct catgtcgatc
    26701 ttttctggct ctgcttggga atatgatgat gcctctgggc agtattatct gcacatattc
    26761 agtaaaaaac agcccgactt gaattgggaa aatgctgaat tgcgtcaaag catttatgac
    26821 atgatgaatt tctggattga taaggggata ggtggctttc gcatggacgt cattgacctg
    26881 attggtaaga ttccggattc tgaaattaca ggcaatggcc caaggctgca tgaatacctc
    26941 aaggagatga accaggcaag ctttgggaat catgacctga tgactgttgg tgaaacatgg
    27001 ggcgctacac cggaaattgc tcgtcagtat tcacgtcctg aaaataagga gctgtcaatg
    27061 gtctttcaat ttgaacatat cggcttgcag cataagccaa atgcttctaa atgggattac
    27121 gcagctgagt tgaatgttcc ggctctcaag gagattttta gcaagtggca gacagagcta
    27181 aagctaggtg aaggctggaa ctcccttttt tggaacaatc atgacttgcc tcgtgtcgtc
    27241 tccatttggg gaaatgatac agtatataga gagaagtctg ccaaggcaat ggctattttg
    27301 ctgcatttaa tgcgtgggac accttatatt tatcagggtg aagagattgg catgaccaat
    27361 tacccctttg agcgcttgag tgatgtgaat gatattgaat cactgaatta tgccaaggag
    27421 gctatggcta atggcatgtc agaggaggct gttcttgatt gtatttgtag ggtgggtcga
    27481 gacaatgcaa gaacaccaat gcaatggagc agtcaaaaga acgccggctt ttcaactgct
    27541 gatcagacct ggctgcctgt caacccaaat catcaagaga ttaatgtggc tagtgctcta
    27601 gctgatcctg attctgtttt ttacacctat caaaagctta ttcagctgcg tcagacacag
    27661 gattggctgg tggaggcaga ttatcagctg ctggaaacat cagataaggt ttttgcctat
    27721 aagcgtcagc ttggtagaga gacttacctt gttgttgtca atctgtctaa tcaagagcag
    27781 ttttttgaag aaagtcttca taaggcccaa gtgattatca gcaataccga tgtgcaggca
    27841 gtcgtagaaa gtcaacagct ggagccttgg gacgcctttt gtgttaagct tgatgagacc
    27901 ttgtagccta gctgcttgct gtgcctcagc tcaataatcg tagcgattct ttgagaattt
    27961 tgacaaattg ctgtatgatt agtagaagaa ttagatacaa aagaggaggc tgagatgacc
    28021 gttgaagaaa ccatgacctt tgcaaaaagc attgcagcat ttagataggt agagattagt
    28081 gaggtagtca ctaggctagc agcaggtgag gacatcaccg tctttttagg cagagcgacc
    28141 tgtccttatt gtcgtcgctt tgcacccaag ctagcaagcg tagcaaggca ggagcataag
    28201 gatattttct ttgtagatag tgaagactca acagagcttg cagacctgca ggcctttcgt
    28261 gagcgctatg ggcttgctac tgtgcctgcc ctgctcatta gtcgtcatca ggaggtcaag
    28321 gcagtctgtg attctagctt gactgaggaa gccattttgg ctttcctaga gcagtgacag
    28381 acagctaatt atctggtgca agtaatagaa atgtaatcag tcatgtcttg ctatgtgagt
    28441 ccaaatctgc tatagtagga catgactttt agacgaaata aggagatatt atgggcttac
    28501 caacaatttt aatgtttgtt gtcatgattg gtttaatttg gtttatgcag cgtcagcaaa
    28561 aaaagcaggc gcaggagcgc caaaatcagc ttaatgcgat tgaaaaaggc gatgagattg
    28621 tgacgattgg tggcatgttt gcagtggtcg atgaggttga tttagcagca aagcgaattg
    28681 tcttagatgt tgatggtgtc tatctgccat ttgagctatc agcgatcaag cgcgtggtcg
    28741 aaaaaggaag tgcagtgaca tcagctgatg tggatacgac agagactgca gttgatgaca
    28801 cagcggttga ggcttcagac gaagctgaat cagctattga gacaaattaa gaaaatgagg
    28861 tctgaagcat tagtgtttca gactttttta ggtgatgata gcaggtagcc agacagagct
    28921 gtcatgtgct atggaaatat cgtctacaac gagaaaaagc gagccaaacc gcatgaaata
    28981 tggtaaaata tgaggtaagt atgcttgtga ataaggaaaa aacatgtttg gattaaaagc
    29041 gaagtcaaaa aaaatcgttt tggataggat tccaaagcac attgggatca tcatggatgg
    29101 taatggacgc tgggcgaaaa aacgcttaaa gccgcgtgtc tttggacata aggcgggtat
    29161 ggacgctttg caggaggtaa cgattgcagc ttcagattta ggggttaagg tgttaacagt
    29221 ctatgccttt tcgacagaaa attggtcaag accacaagat gaggtgagct tcattatgaa
    29281 cctgcctgtt gagttttttg ataagtatgt gcctgagctg cacaaaaata atgtcaaggt
    29341 gcagatgatc ggtgagacca accgcctacc taaggataca ctaaaggcct tggaagcagc
    29401 tattgctaag acaaggcaaa atactggctt gattctaaac tttgctctta attatggggg
    29461 tcgcgcggaa atcaccaatg ctgtcggtct cattgctcaa gatgtcctag acgccaagct
    29521 gaaccctggt gacattaccg aggatttgat tgccaactat ttgatgacgg atcatttgcc
    29581 ctatctctat cgcgatcctg accttattat cagaacgagc ggtgaattgc gcttgagtaa
    29641 ttttatgcct tggcaatcag cctatagtga gctttacttt acgccggtgc tgtggcctga
    29701 ttttaaaaga gctgaactac taaaggccat agaggattat aaccatcgtc atcgccgttt
    29761 cggtgctatt taaggagaga gtatgagaga acgtttcatt tggggtggtg ttgcagctgc
    29821 tgttttccta ccctttttac tcattggcag cttacccttt caattgtttg taggtgtgct
    29881 tgccatgatt ggtgtatcag agctgttaag aatgaagagg cttgaggtct tttcctttga
    29941 gggtgttttt gccatgctag cagctttcgt tttgacagtg ccgttggatc attacctgac
    30001 ctttttgccg atggacgcta gttttgcttg ttacgggctg ttggtgtttt tccttttagc
    30061 aggaatagtg attagcagcg attcttatgg ctttgaggat gctagctttc cgattgcagc
    30121 tagcttatat gttggtattg gctttcataa tctggttaat gcgcgaatga cagggataga
    30181 caaggttttt ctggctcttt ttattgtctg ggcgactgat attggagctt acttgattgg
    30241 gcgccgattt ggtaagcgaa agctcctgcc aaaaatatca cccaacaaaa caattgaggg
    30301 cagccttggt ggtatagtca gtgcggtgct tgtttccttt gtgtttatgc tctttgataa
    30361 ggctgtttat gctcctcatc attttggaac aatgttgatt ttggtggctc ttttttctat
    30421 ttttgctcag tttggagatt tggttgaaag tgctgtcaaa agacatttcg gagttaagga
    30481 ctcaggcaaa ttgattccag gccatggtgg tattttagat cgttttgatt cgatgatctt
    30541 tgtttttccc attatgcatc tatttgggtt attttaaagc tcattatcaa tagactgaaa
    30601 ggaaatctat gttaggaata attaccttta ttattatttt tggtattctt gtgcttgtcc
    30661 atgagtttgg ccatttctat tttgctaaac gatctggtat tttagtcaga gagtttgcta
    30721 ttggcatggg accaaaactc ttttcgcatg ttgatcagca aggaacgctt tacacgatcc
    30781 ggctattacc gcttggtggc tatgtgcgaa tggcaggctg gggtgatgac acaactgaga
    30841 taaaaacagg aacgcctgct agcttaacgc ttaatgatca gggcttggtc aagcggatta
    30901 acctgtctca gagcaagctt gatccgacta gcctgcctat gaatgtgact gcttatgact
    30961 tagaagataa gttgacgatt acagggctgg ttcttgatga gatcaagacc tattcggtag
    31021 accatgacgc gaccattgtc gaggaggacg gtacagagat ccggattgcg ccgcttgatg
    31081 ttcagtatca aaacgcaagc attggcggtc gtttgatcac caattttgca ggacctatga
    31141 ataattttat tctaggtatt gttgtcttta ttttgtttgc ctttgttcaa ggtggtgtgg
    31201 ctgattatca tagcaaccat attcgtgtgg tggaaaatgg cgcagcagcc aaggctggta
    31261 ttagagacaa tgatcagatt ttagagatta atcatcaaaa gattaatgac tggtatgagt
    31321 tgacgcaggc cgttactgat tcagcagcag atgttaaggc taagggcaag ctagagatta
    31381 cctatcagac aggtgatcag gttaagacta tagcactgaa gcctgaaaaa aaaggcgatc
    31441 agtaccttat tggtgtccag tacccactaa aaacaagtct gacagacaag ctaataggtg
    31501 gctttgagat ggctggtaat ggtgctctag tgattgtcac tgctctaaag agtttgatta
    31561 cctcctttag cctagataaa ttaggtgggc cagttgccat gtatcagatg tccaatcagg
    31621 cagcaaagaa tggtttagag tctgtcttgt ccttgatggc aatgctctct atcaatttag
    31681 ggatttttaa tttgattccg attcccgcac tagatggtgg taagatcctg atgaatgtga
    31741 ttgaagcact tcgtcgtaag ccattaaagc aagagacaga gacttatatt acccttgcag
    31801 gtgttgcgat tatggtggta ctcatgattg cagtgacctg gaacgatatt atgcgagcct
    31861 ttttccaagg ctgatggtct ctctcattta aaggagagcc taaaaggctt aatgtaacag
    31921 aaataacaag agatatagtg tcattattgt ggttctaaga ccttgcaaat gcagcaaaag
    31981 cttagccaat atagctcatt ttgtctcttt tttagaaatg aattctcaac gaaaggaaag
    32041 agagctgttg accaagctgg gctaaggcct acagctgaaa tcaaaatgct agacctgcta
    32101 ttagtctaag ggcgttttga gctgctctct atagcttatt ttaatgaaac aaagtaaaat
    32161 gcttatccca accctgcgcg aaatgccaag tgacgctcag gtaatcagtc atgccctcat
    32221 ggtgcgtgcg ggctatgtcc gtcaggtatc tgccggtatt tatgcctatt tgccattagc
    32281 tcatcgtaca attgaaaaat tcaagacgat tatgcggcag gaatttgaca aaattggtgc
    32341 tgttgaaatg ctagcacctg cccttttaac agctgacctc tggcgtgaat caggccgcta
    32401 tgagacttac ggtgaggacc tttacaagct aaaaaaccgc gacaaatcag actttatctt
    32461 aggtcctacc catgaagaaa cctttactac actggtgcgt gatgcggtta aatcctataa
    32521 gcagctgccg ctcaatctgt atcagattca atccaaatat cgtgatgaaa agcgtcctcg
    32581 taatggcctg cttcgcacac gtgaatttat catgaaggac ggctatagct ttcatcaaag
    32641 ctatgatgat ttagatgtca cctatgacgc ctatcgtcag gcctatgagg ctatttttac
    32701 cagagcaggc ttggatttca aaggaattat cggtgatggt ggtgctatgg gtggtaagga
    32761 ttcgcaggaa tttatggcta tcacaccgga ccgtactaat ttagaccgct ggctggtctt
    32821 agacaagtct attccgtcat tggctgacat tccagaggag gtcttggaag agattaaggc
    32881 cgagctggct tcatggctgg tttcaggaga ggacaccatt gcttattcaa gtgaatcaag
    32941 ctatgctgct aaccttgaga tggcaaccag tgagtacaag tcctcatcaa aggtaacagc
    33001 cttagatgat ctcgtcgaga ttgagacacc aaattgtaaa accattgatg aagtggcggc
    33061 ctttcttgac gttgctgagc atcaggtcat taaaaccctg ctctttatgg tggaccatga
    33121 gcctgtgctt gctttattgg ttggaaatga ccagatcaat gctgtcaaat tgaaaaacca
    33181 cctcggtgca gacttcttag agccagctag cgaggaggag gcgcgtgcta tcctaggtgc
    33241 aggctttggt tcacttggtc cagttcattt gacagatggt atccgtattg tggctgatcg
    33301 taaggtccaa gaccttgcta atgctgtagc tggagccaat aaagatggtt atcacctgac
    33361 tggtgtcaat ccaaatcgtg atttccaagc agagtatgct gatattcgtg aggtaaaaga
    33421 gggagagacc tctccagata gacatggcgt gctgcagttt gccagaggta ttgaaatcgg
    33481 tcatatcttt aagctgggga cccgctattc tgatagcatg gcagctaata tccttgatga
    33541 gaatggcaga gcagttccga ttgtcatggg ctgctatggt attggggtta gtcgtatcct
    33601 atcagcagtc attgagcagc atgctcgtct ctttgtcagc aagacaccaa agggtgatta
    33661 tcgctatgct tgggggatta atttccctaa agagctagct ccgtttgatg tgcatttgat
    33721 taccgttaat gtcaaggatc aggaggcgca ggacctgaca gaaagagtag aggctagtct
    33781 gatggccaag ggctatgatg tcctcactga tgaccgcaat gagcgtgtcg gctctaagtt
    33841 ctctgatagt gatttgattg ggcttccgat tcgtgtgacg attggtaaaa aagcagctga
    33901 gggcattgtt gagatcaaaa tcaaagcaac aggtgacagc attgaggtgc acgctgatag
    33961 cttgattgaa actcttgaca ttctcacaaa ggacaactaa tgatatgagg tcaacgatgg
    34021 ttgatctctt tttgtatgct ataatgaaag catgacaatt gaggaattac agcagctggt
    34081 gctagcagat catgagctaa tgactattct aagcattata gagaccttgc ctttaaagga
    34141 ttgttggctg gcagcaggtg caattcggaa cgctatttgg aatcatttag cttatgggat
    34201 aggctttgat ccgctgacag atgtagatgt ggtctttttt gaccctgaga tctcttacga
    34261 agctgagcag ctgctagaag agcagcttaa gtgtgcttat cccatgtacc aatgggaggt
    34321 tcgcaatcaa gcctatatgg cagcacataa ccccaagacg cctccttatc gatctagtca
    34381 agacgctatc acaaagtatc cggagcgctg tacagcgatt gctgttagac ttgtaggagg
    34441 acagctagag gtttttgctc cctatggttt agcagacatt agtcactttg tctgtcggcc
    34501 aacaccgcat tttttagagg attcagagcg tatggactgc tataggcagc gcctagcaaa
    34561 gaaggactgg cacaagaaat ggccacagct gacctaccac gactgctaag tcagaggaaa
    34621 caaagcaggc taggagctcc gtacagccaa gcaattagtc cgctcccaga cccgttagct
    34681 acagctctca cctagtcaaa acaagcacat gaacagatca ttggcagata gccttgcctt
    34741 tgcagatatt gtcacaccct atttagctgt accatgtgtc ttatgatagg cgtgatagtg
    34801 ctgtcagaag cgccagctga gccagaaaaa gcgttaagcc tacagcaagg ggcttttaac
    34861 ctttggtatg ttgtcttgta ggagaggtcg aaaatgatca ctatttatga taaaatagac
    34921 cctaagaaaa tcaggagaaa gctatgtcag atttattcgg taaattgatg gaacaaattg
    34981 aaatgccact tgagataaga caatcaagtg ccttttcgtc tgctgatatt atcgaggtca
    35041 aggtgcattc agtgtctcgt ctgtgggaat ttcatttttc ctttgcagag gttctcccga
    35101 tagagagcta tcgagagctg tcagataggc ttgtgagaac ctttgaggca gcagatatta
    35161 aggtaacatt tgacatcaag gcagagacaa ttaattattc ggatcagctg ctgcaagcct
    35221 actatcaaga agcatttgag catgagccct gtaatggggc tagcttcaag tcatcttttt
    35281 ctagacttca ggtcaggtat gaccatcatc agctgatcat tatggcacct gactttgtga
    35341 ataatgatca ctttaggaaa aatcatttac ccaatctggc agctcagttt gagcgctttg
    35401 gctttgggag gctagcgatt gatatggtgt ctgatcagga gatgacagac catttgacaa
    35461 aggactttga gaccaaccgt caggctctgg tggaaaaggc tgtacaggat aatatcgcag
    35521 cacagcaatc attggaggcc atgcagccac cagctgagga ggcagcacca agcccaagcc
    35581 ttgactatag agagcgtatg gctcagcgcc aagcaagctt tgataaggcg gtcattacac
    35641 caatgattga ggtggataca gaagaaaatc gcattgtttt tgaaggaatg gtctttgatg
    35701 tggagcgcaa gacgacaaga acaggccgcc atatcatcaa cttcaagatg acagattaca
    35761 cctcctcctt tgccatgcaa aaatgggcca aagatgacga tgagctcaga aaatttgatc
    35821 tgattgcgaa gggagcttgg ctgcgcgttc agggaaatat cgaaaacaac cccttcacca
    35881 agagcctaac catgaatgtg cagcaggtta aggcgattgt tcaccatgag cgtaaggatc
    35941 tcatgccaga agggcaaaag cgtgttgaat ttcatgcaca cactaatatg tccacaatgg
    36001 acgctctacc gacggtagaa gacctgattg atacagcagc caggtgggga catcaggcag
    36061 tagcgattac tgaccacgct aatgttcaga gctttccgca tggctatcat agagcacgca
    36121 aggcaggaat caaggcaatc tttggcttag aggccaatat tgttgaggat aaggtaccta
    36181 tttccttcaa tcctgtcgct atggacctgc atgaagccac ctatgttgtc tttgacgtgg
    36241 agaccaccgg cctttctgcc atgaacaatg atttgattca gatcgcagct tccaaaatgt
    36301 tcaagggaaa tatcattgag cagtttgatg agtttatcaa tccaggccac cccttatctg
    36361 cttttacaac agaattgaca gggattacag ataatcattt ggtaggagct aagcctatac
    36421 agcaggtgtt agaggcattt caggcctttt gtcagggcac tatcctagtt gcccacaatg
    36481 ctagctttga cgtgggattt atgaatgcca actacgatcg gtatggttta gcaaaaatca
    36541 gccagccagt tattgacacc ctggagcttg ccagaaacct gtaccctgag tataagcggc
    36601 atggcttggg ccctttgact aagcgctttc aggttagcct tgagcaccat cacatggcca
    36661 attacgatgc tgaagcaaca gggcgtttgc tctttatctt cctaaaggaa gctagagaaa
    36721 agcatgggat tacaaacctg cttcagctca atacagactt agtggcagag gattcctata
    36781 agaaagcacg gatcaagcac gccacgatct atgttcaaaa tcagctaggt ctcaaaaaca
    36841 tgtttaagct ggttagcctt tcaaatgtga aatattttga aggtgtgcct agaattccaa
    36901 gaaccgtcct tgatcagcat cgtgaaggct tgctgcttgg gacagcctgc tcagacggcg
    36961 aggtctttga cgctgttttg acccaaggaa ttgacgctgc tgttgatctg gccaaatact
    37021 acgattttat cgaaatcatg ccgcctgcaa tttaccagcc cttggtagtc cgagagctaa
    37081 tcaaggatca agcaggagtt gagcagatta ttcgcgattt gattgaggtc ggccgcagag
    37141 ctgaaaagcc tgtcctagct actggaaacg tgcactacat tgagccagag gacgccatct
    37201 atcgtgacat tatcgttcgt agtctagggc aaggtgccct gattaaccgt actattggcc
    37261 gcggagaggc tgccaagcct gtcccgctac cagaggctca ttttagaaca accaatgaaa
    37321 tgcttgatga ttttgccttt ttaggtcagg acttggccta tgaggttgtg gtgcaaaata
    37381 cccaagccct tgctgatcga attgaaaagg tggaggttgt taaggatgat ctgtacaccc
    37441 catatattga taaggcagaa gaaaccgttg ctgagctgac ttatcaaaag gcctttgcta
    37501 tctatggcaa cccacttcca gatatcattg atctgcgcat tgaaaaggag ctaacgtcca
    37561 ttttgggaaa cggctttgcg gtgatttatc tagcctcaca aatgctggtt aatcgctcta
    37621 atgagcgtgg ttatctggta ggctcacgtg gctctgttgg ttcaagcttt gttgcgacca
    37681 tgattggcat cacagaggtc aatccaatgc cgcctcatta tgtctgccca agctgccagc
    37741 agtcagagtt tatcacagat ggctcggtcg gctctggcta tgatttgcca aacaaggcct
    37801 gtcctagatg tgggacgctg tacaaaaagg acggacagga tattcctttt gaaaccttcc
    37861 ttggctttga tggtgataag gttccagata ttgatttgaa cttctcagga gatgatcagc
    37921 ccaatgccca cttggacgtt cgtgatatct tcggggaaga atacgccttt cgtgcaggta
    37981 ctgttggtac tgtcgctgaa aaaacagcct atggctttgt caagggctat gagagagatt
    38041 atggcaagtt ttacccagat gcagaggttg atcgtctagc tgctggtgct gctggtgtta
    38101 agcggacgac tggtcagcac cctggtggga tcgttgttat ccctaactat atggacgttt
    38161 atgattttac acctgtgcag tttccggcag atgatgtgac agcctcatgg cagacgaccc
    38221 actttaattt ccatgatatt gatgaaaatg tcctaaagct cgatgtactc ggtcatgatg
    38281 atcccaccat gattcgtaag ctgcaggatt tatcaggtat tgatccgatt actattccag
    38341 cagatgatcc tgacgtgatg gcactttttt ctggaacaga ggtgctcgga gtgactcctg
    38401 aacaaattgg aacaccaaca ggtatgcttg ggatcccaga gtttggaacg aactttgttc
    38461 gtggcatggt gaatgagacc cacccaacga cctttgcaga attgctgcag ctatcaggtc
    38521 tatcgcatgg aacggacgtc tggctgggta atgctcagga tctgatcaaa gaaggcattg
    38581 ccaccctaaa aacagttatc ggttgtcgag atgacatcat ggtttacctc atgcatgctg
    38641 gtctagagcc taagatggcc tttaccatca tggagcgtgt gcgtaagggg ctctggctaa
    38701 agatttccga ggaggagcgc agctcctata tcaaggccat gcggcaaaac aacgtcccag
    38761 actggtacat cgaatcctgt ggtaaaatca agtacatgtt ccccaaggct cacgctgccg
    38821 cctatgtttt gatggcattg cgagtggctt atttcaaggt tcatcacccc atcatgtatt
    38881 actgtgctta tttctctatt cgtgccaagg cctttgagct caaaaccatg agtggtgggc
    38941 tagctgctgt caaggctcgc atggaggaca tcagcaacaa gcgcaagcgc aatgaagcct
    39001 caaacgttga aaatgacctg tttaccactt tagaaattgt caatgaaatg cttgagagag
    39061 ggtttaagtt tggcaagcta gacctttaca agagcgaggc aactgagttt caaattgaag
    39121 gggataccct aattccacct tttattgcct tagaaggctt gggagaaaac gttgctagac
    39181 aaatcgtcaa ggctcgccaa gatggtgaat ttctatcaaa aatggaatta cgcaagcgtg
    39241 gtggtgcttc tgccactcta gttgataaga tggacgagct gggcatttta ggaaatatgc
    39301 cagatgacaa tcagctgagt ctatttgatg actttttcta agattgcaca gccctaatat
    39361 tgtctatgtt agcttgtcat acagtgaaga gcagggcagg aaggcttcct gtcctctttt
    39421 tgtcaatacg caaagaaagc ccaaaaaaga acgaggaaaa gcatgaatga attagacaaa
    39481 aatcctgcct taaaggcaat ggttgttttt agaaaagcac agcgtacctt agatgctcaa
    39541 agctccgcct tttttcaaaa ggccaatctg actcctaccc aatttagcgt cttagaggtg
    39601 ctttattcca aaggaagcat gagaattaac aagctcatcg gttctctctt ggcaacctct
    39661 ggcaatatga ccgtagtgct gaaaaatatg gagagaaatg gctggatcag ccgctgccaa
    39721 gatgctaaag ataagcgtgc ctgcttggta cagctaacgc cagagggcaa agccttgatt
    39781 gagactatcc tacctgagca tatcaaacgt gttgaagccc ttttttcagt gctgacagag
    39841 actgagcaaa aacaattgat tacgctttta aagaaattta aagaactcta agcaaatggc
    39901 tttacaggat ctcccaagta ggatataatc actacatagt acaaaaagat actaactagt
    39961 cataataagt catcaagaca gcagatggct agttaccaga taatcaatgg gagacaaagc
    40021 atgaaacaaa ttttaatcat taatggttca ttacggacag gttcatttaa tcatcagctt
    40081 gctcaagcgg ctgagcagct acttgaaggc aaggcagctg tatcttactt ggactgggaa
    40141 caggtaccta tgtttagtca ggatttagaa gcaagcaccc ctgagtcagt ggcaggcgta
    40201 cgagaagcca ttcaagcagc agatgctatc tggatttttt cacctgtcta taattttgca
    40261 atcccgggct ctatcaaaaa cctattagac tgggtatcac gcgcccttga tttgtcagac
    40321 ccatcaggac catcagcaat caatggtaag gtagttaccg tatcatctgt tgctaatggt
    40381 gggcacgagc agctatttgc gcaataccag gacctgctgc cctttatccg tacgacagta
    40441 gttggtaact ttaccaaagc cgctgtcaat ccagaagcat gggcgacagg tgttcttgat
    40501 atttctgagg aaacaaggca aagccttgca gcacaggcag aagcccttct tgaagccatt
    40561 cactaagact ctctgagcat taaacagata aagctgcagc taggatcaaa aagcagctag
    40621 acacataaaa agagcttaaa ccagaaatgt acggcactcc aaaagctaga caaaaactct
    40681 agcgattggg gtacaggtca aaacggtttt aagctctttt ttagacttat tttatagtag
    40741 taacttaatt aagaattagc ataccctctt tagcctcaaa ggggtttttc gcattaatac
    40801 ggtcatagaa taagacacca ttaatatgat caatctcatg ctgaaccacg atagcattgt
    40861 agccctttag cttaatgcgg tgcttttcat tgtgcttatc gtaatattcc actgtcacac
    40921 gcgcatgacg gacgacatag ccttccacca cacgatcaac agacaaacac ccctcaccgt
    40981 cagcaagagc agcgtcttga acagaatgag acacaatttt aggattatag agcacttcct
    41041 ccatgctgta agcctcctta ggtggattgc cctcgctgtc ttcaggattt ggaaccagaa
    41101 cagcgatgat acgctttgac acatcaatct gaggtgctgc tagaccaact cctgctcgaa
    41161 gccctaattt ttctcccatg acagggtctt gagaatgctt taaaaattgc atcatttttt
    41221 cacctaaaat gatgtcatca tcactaagag gaaactcgac ctccttagcc acagcacgaa
    41281 gcgtaggatt gccttcgcgg ataatatcat tcatatcaat gagatgctgt gctttaatta
    41341 atttatcttg tgcagacatt ttgcctccct ttttttatat ttgataatgg ctttactata
    41401 tcacaaaatc cttattttta aaagataagg caggccagtg atgacgatat tagctaactc
    41461 tatcagatat attaaattat ttaaaaaata gttcgttaat tagcacgaca tatatataag
    41521 aaatacacag gaattctaat aattaataga taaaaaatga taatcgttcg taaataaatc
    41581 aaacatctaa tctaaaaaaa ttatattgtt ctgattgttc ggtaattaaa gcaatagcgc
    41641 ttgtcgaaaa actaatgttc tcttaatatc aggtagccat gccaagggtt ttgtgttaaa
    41701 gtataggacg ttcaaaaaat gaaatggaga gactaatgag aacacaattg aaaaaattgc
    41761 tggcaggaac agcagcaggt accctgctgc tgtttaacct gacctgcgga atgattaatg
    41821 cttttgcaga gcagtattac gggtggagtg acgggagtag cagctatccg agtgctttgt
    41881 atgttacacc ggtaggagat actacgaaaa agatagctat tcctgtttat tgctttgact
    41941 ataagtttca ggagccactt gcttggaaag aaataactca accgtcacac ttgattgtct
    42001 atgataagta tgatggcaaa aatttgatgg cagcactggt tgaaaaacct aatatggtaa
    42061 gctatgagac taaaactaaa cttcaaacac ttttaaagac aaagtcaaat ctaataactg
    42121 caattttaag tagaggttat ccaaacaaaa gtttttttga taagtataaa aaattaactg
    42181 atgaagataa aagacgagtg acacaatgtg ctctttggta tcatactgac aatatttcag
    42241 aacaagatct tatcacaaaa catttggatg gggattcagg tgaaaaaagt caagcgctaa
    42301 aggagttaat aggggttgta aaaaatactt ctaatgagtt aggagaggga ttaaccttct
    42361 atactcgtta taatgataga tatggtccta aatatcaaaa cctaataggc tcaattattg
    42421 ttcccgaaga gcctcagaat gatcttgaaa ttggtggtgg aaatgttatt gatttaaact
    42481 accaatctgg accaatggta gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg
    42541 acactaaaaa gcctgatgtg attattggtg gtcagggaag cgttactgag actactgagg
    42601 atactcaaaa gggtatgagt ggcagtactg agactcagcc agaggttgag gatactaagc
    42661 agccacaatc agatattatc ctaggcggac aaggcaatgt gattgacaca actgaaaata
    42721 cccaagaggg catgggtggc caatcaggtg atactacaga gactgaggat accaagcagc
    42781 cacaatcaga cattatccta ggtggacagg gcaatgtaat tgacaccact gaaaatactc
    42841 aagagggtat gagtggttcc aacaatggtc aaacatttga ggaggacaca cgtcctaagc
    42901 tggaattcca ttttgataat gaagtgccta acgatgatga cgctcctaaa ccagagcaac
    42961 cagaacagcc agagaagccg gagcaaccaa ggaagccaca gcaggagcag caaagcctac
    43021 cacgtccaat agagggcaac cagtcattgc caaaaacaca tgaggcaaaa ggtgtactgg
    43081 ctctagtagg agtaggaatc cttgctatgc taggactagg cttttggttt agaccttatc
    43141 aaaaagacta aatcaaggct cagcagctat ttaagctaaa cagctgtgct cagctaaatg
    43201 ataaaacaat taagattgga gaatgtggct attagtagct tctccaatct tttttgatag
    43261 cagcatgtgc tttttctgcc gtattttatt gagaataata gttgaccagt ctaggcgatt
    43321 ttgctagaat agagaggtcg caagacagac taactttttc ttggttttag gagtgccaac
    43381 cctaaaactc ggattaagca aaaaaggaga attattatgg caatctcaaa agagaaaaaa
    43441 aatgaaatta ttgcacaata tgcacgtcac gaaggtgaca caggctcagt tgaggttcag
    43501 gtagctgtcc ttacttggga aatcaaccac ttgaacaacc acatcaagga gcacaaaaaa
    43561 gaccacgcaa cttatcgtgg attgatgaaa aaaatcggac accgtcgtaa cctattagca
    43621 tacctacgtc gtacagatgt taaccgttac cgcgagttaa tccaatcact tggacttcgt
    43681 cgttaattgg cttgacagag gtcattttag agataaccaa gttctattga aaaaagatct
    43741 gct
//
LOCUS       DARYJX010000017        40180 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYJX010000017 DARYJX010000000
VERSION     DARYJX010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40180
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            310..2454
                     /gene="pnp"
                     /locus_tag="TU257_000894"
     CDS             310..2454
                     /gene="pnp"
                     /locus_tag="TU257_000894"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL0833917.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2447..3199
                     /locus_tag="TU257_000895"
     CDS             2447..3199
                     /locus_tag="TU257_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL0833918.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3211..3747
                     /gene="cysE"
                     /locus_tag="TU257_000896"
     CDS             3211..3747
                     /gene="cysE"
                     /locus_tag="TU257_000896"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL0833919.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3865..5208
                     /locus_tag="TU257_000897"
     CDS             3865..5208
                     /locus_tag="TU257_000897"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL0833920.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5201..5608
                     /locus_tag="TU257_000898"
     CDS             5201..5608
                     /locus_tag="TU257_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL0833921.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5825..6613
                     /locus_tag="TU257_000899"
     CDS             5825..6613
                     /locus_tag="TU257_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833922.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6662..7408
                     /gene="rlmB"
                     /locus_tag="TU257_000900"
     CDS             6662..7408
                     /gene="rlmB"
                     /locus_tag="TU257_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL0833923.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7409..7927
                     /locus_tag="TU257_000901"
     CDS             7409..7927
                     /locus_tag="TU257_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL0833924.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8111..8971
                     /locus_tag="TU257_000902"
     CDS             8111..8971
                     /locus_tag="TU257_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0833925.1"
                     /translation="MTFVLMTDSTADLGSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9510..9956
                     /gene="rplM"
                     /locus_tag="TU257_000903"
     CDS             9510..9956
                     /gene="rplM"
                     /locus_tag="TU257_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL0833926.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9976..10368
                     /gene="rpsI"
                     /locus_tag="TU257_000904"
     CDS             9976..10368
                     /gene="rpsI"
                     /locus_tag="TU257_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL0833927.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10483..11574)
                     /locus_tag="TU257_000905"
                     /pseudo
     CDS             complement(10483..11574)
                     /locus_tag="TU257_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11628..12146)
                     /locus_tag="TU257_000906"
     CDS             complement(11628..12146)
                     /locus_tag="TU257_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0833928.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12299..12583
                     /locus_tag="TU257_000907"
     CDS             12299..12583
                     /locus_tag="TU257_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0833929.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12592..13077
                     /locus_tag="TU257_000908"
                     /pseudo
     CDS             12592..13077
                     /locus_tag="TU257_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13129..13416
                     /locus_tag="TU257_000909"
     CDS             13129..13416
                     /locus_tag="TU257_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL0833930.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13431..13721
                     /locus_tag="TU257_000910"
     CDS             13431..13721
                     /locus_tag="TU257_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833931.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13714..14076
                     /locus_tag="TU257_000911"
     CDS             13714..14076
                     /locus_tag="TU257_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0833932.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14076..14432
                     /locus_tag="TU257_000912"
     CDS             14076..14432
                     /locus_tag="TU257_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0833933.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14776..16320
                     /locus_tag="TU257_000913"
     CDS             14776..16320
                     /locus_tag="TU257_000913"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL0833934.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16322..17584
                     /locus_tag="TU257_000914"
     CDS             16322..17584
                     /locus_tag="TU257_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0833935.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYSTDKT"
     gene            17593..18198
                     /locus_tag="TU257_000915"
     CDS             17593..18198
                     /locus_tag="TU257_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0833936.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            18213..19421
                     /locus_tag="TU257_000916"
     CDS             18213..19421
                     /locus_tag="TU257_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0833937.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            19424..22519
                     /locus_tag="TU257_000917"
     CDS             19424..22519
                     /locus_tag="TU257_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL0833938.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            22687..24138
                     /locus_tag="TU257_000918"
     CDS             22687..24138
                     /locus_tag="TU257_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0833939.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
     gene            24500..24787
                     /locus_tag="TU257_000919"
     CDS             24500..24787
                     /locus_tag="TU257_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL0833940.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
     gene            24777..25115
                     /locus_tag="TU257_000920"
     CDS             24777..25115
                     /locus_tag="TU257_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0833941.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(25707..25868)
                     /locus_tag="TU257_000921"
     CDS             complement(25707..25868)
                     /locus_tag="TU257_000921"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0833942.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(26482..26625)
                     /locus_tag="TU257_000922"
     CDS             complement(26482..26625)
                     /locus_tag="TU257_000922"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0833943.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            complement(26926..27969)
                     /locus_tag="TU257_000923"
     CDS             complement(26926..27969)
                     /locus_tag="TU257_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL0833944.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            complement(28046..29056)
                     /gene="galE"
                     /locus_tag="TU257_000924"
     CDS             complement(28046..29056)
                     /gene="galE"
                     /locus_tag="TU257_000924"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0833945.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            complement(29066..30550)
                     /gene="galT"
                     /locus_tag="TU257_000925"
     CDS             complement(29066..30550)
                     /gene="galT"
                     /locus_tag="TU257_000925"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL0833946.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            complement(30554..31726)
                     /locus_tag="TU257_000926"
     CDS             complement(30554..31726)
                     /locus_tag="TU257_000926"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL0833947.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            31867..32868
                     /locus_tag="TU257_000927"
     CDS             31867..32868
                     /locus_tag="TU257_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0833948.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            33033..33914
                     /locus_tag="TU257_000928"
     CDS             33033..33914
                     /locus_tag="TU257_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0833949.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            34539..36086
                     /locus_tag="TU257_000929"
     CDS             34539..36086
                     /locus_tag="TU257_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0833950.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            36413..37336
                     /locus_tag="TU257_000930"
     CDS             36413..37336
                     /locus_tag="TU257_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0833951.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            37351..39762
                     /locus_tag="TU257_000931"
     CDS             37351..39762
                     /locus_tag="TU257_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0833952.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVEEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
BASE COUNT        12031 a         7389 c         9039 g        11721 t
ORIGIN      
        1 gcaggtcttt ttttgctgcg tcatcagcgg cttagcgtgc ttggctgtag ggctatagtg
       61 ataaaagaga gtgctgctgg tattgacagc cctttcaaac tttttctagg aatgcctttt
      121 agggtcgtga atttttaact attttatggt aaaatgtagc agatacgtcg tttgatacaa
      181 agaggagtgt gtaattcctt acagattgct ctttgtagca aaacaacgta tagccataaa
      241 aaataaaagg ctagcaagct ttggtcgggt caaacggcta tggtaggcta gctcgttcaa
      301 ggagaaagaa tgtcaaaaca aacatttaca acaacctttg caggcaaacc acttgttgtt
      361 gaggtcggtc aagtagccaa gcgagcaaat ggtgccactg tcgttcgtta tggggagtct
      421 acagtgctaa ctgctgctgt catgtctaag aagatgtcaa caggagactt tttcccgctt
      481 caagtcaatt atgaagaaaa aatgtatgcc gcaggtaaat ttcccggtgg ctggatgaag
      541 cgtgagggac gtccgtcaac agatgcgacc ttaaccgctc gcttgattga ccgccctatc
      601 cgtcctatgt ttgctgaggg ctttcgtaat gaggtccagg tgattaatac tgtcctgtct
      661 tatgacgaag atgctagtgc ccctatggct gctatgcttg gtagctcatt agccctatcg
      721 atttcagata ttccttttaa tgggccgatt gctggtgttc aggtggccta tgttgagggt
      781 gaatttatca tcaatcctga taaggcccag caggaggctt cattattaga gttaaccgta
      841 gcaggaacaa aagatgcgat caatatggtt gaatctggtg ctaaggaatt gccagaggct
      901 attatgctag aagcactttt ggttggccat aaggctatac aggagttgat tgcttttcaa
      961 gaagagattg ttgcagcggt gggcaaggaa aaggctgagg tagagctatt acaggttgct
     1021 gctgatttgc aggctgagat catagagact tacaatgctg atttgcagca ggctattcag
     1081 gttgaggaga aaaaagcacg tgaagccgca accgaggctg tcaaggagcg tgtcatagct
     1141 gcatacgagg agcgttatgc agcagacgaa gagcatgacc gtatcatgcg tgatgtggct
     1201 gaaattttgg agcaaatgga gcatgctgag gttcgtcgcc tcatcactga ggataaggtt
     1261 cgtcctgatg gtcgtcgtgt tgatgagatt cgtccgcttg ctgctgagat tgatttctta
     1321 ccaagggtgc atggctcagg cctctttacg cgcggtcaaa ctcaagcttt gtctgtcttg
     1381 actctagccc caatgggaga tactcaaatt attgatgggc ttgagcctga gtacaaaaaa
     1441 cgcttcttgc accactataa tttccctcaa tattctgttg gtgagacagg ccgctacggt
     1501 gcagcagggc gtcgtgaaat tgggcatggt gctttaggcg agcgcgctct tgcacaagtc
     1561 cttccaagcc ttgaggcatt tccatatgct attcgtctag tggctgaggt attggaatca
     1621 aacggttctt cctcgcaggc ctctatctgt gcagggacgc ttgctttgat ggctggtggt
     1681 gtgccgatca aggcaccggt tgcgggtatt gctatgggac ttatctctga tgggaccaat
     1741 tatactgttt taacagacat tcaggggtta gaggatcatt ttggcgacat ggacttcaag
     1801 gttgctggga cacgccaagg gattacagca ctgcaaatgg atatcaagat cgaaggtatc
     1861 acccctcaaa tcctagaaga agccttggcg caggctaaaa aggctcgctt tgaaattctt
     1921 gacttgattg aggcaaccat tgctgagcct cgtccagaat tggcaccaac agcaccaaag
     1981 attgatacca tcaagattga tgttgataag attaaggtgg ttattggtaa gggtggcgaa
     2041 accattgata agattattgc tgagacaggt gttaagattg acattgatga ggaaggaaat
     2101 gtttcaatct actcaagtga tcaggacgct atcaatcgtg ctaaggaaat cattgctagc
     2161 ctagtacgtg aggctaaggt aggagaggtc taccatgcta aggttgtccg tattgaaaaa
     2221 tttggtgcct ttgttaacct ctttgacaag acagatgcgc tggtgcatat ctctgaaatt
     2281 gcttggagcc gcactaccaa tgtctcagat gttcttgaaa tcggtgaaga ggttgacgtt
     2341 aaggttatta aggttgatga taagggacgt attgacgcat caatgaaagc cttggtgcca
     2401 cgcccgccaa agccagaaaa atcagaagca aaaaaagaag gcaaacatga ctaatacaaa
     2461 tgaactagat attcgtttaa gagcctttat caatgcccct gataattttt tagatagcgt
     2521 ggccttggtt aatgcttttc accagtatcc ggtgtgggca gcaaaaaagc cctatgctat
     2581 tgagattgaa ggggtaagga tttttcctgt attcacagat aaggacgaca tggcgacctt
     2641 taaagaggag caaaagagtg cacaagctca gtattgggta gagcgctctg ctcttactgt
     2701 cttggaggag gctgttcatg caggtgctgc tgggctaggc tttaatctca agaaaaaggg
     2761 agattttggc aattctacag tgttcaagtc tgctgatatg attcagttta tgaacaatta
     2821 cacaacgatt ttgaatacct tgatgagtga tgacaatagc gcagcagata ccctggatag
     2881 gctttatctg gtgccggcct ttgtttaccc taaggaagag gagcattact atgacaggct
     2941 ttttccaacc atgtcaactc cagaggggaa gcgttatgtt cctgcctttt caaatcttca
     3001 gagcttcgct aaatggtaca atcaagagga gtttggcggc ctttttagga aatcaggtgg
     3061 tgttatctta acatggaaga tagcagacat ttatcagcca agaaatggca ataatgacat
     3121 agacgagacc tttggggttg ctattgaccc ctttgatgat cagcagattc ttgttgattg
     3181 gtctgatatt gacacataaa aggagtttaa atgggctggt ggaaggacaa tattgatatt
     3241 gtaaagcaac tagatcctgc tgcacgtagc accctagagg ttatcctaac ctaccctgga
     3301 ttaaaggcct tggcagcgca caggctgtca cattttttgt ggcagcatgg ctttaagctg
     3361 ctggctcgaa tgcatagcca gttttggcga ttttggacac agattgaaat ccacccagga
     3421 gctaggattg cttcaggtgt tttcattgac catggggctg gcttggtgat tggtgagacg
     3481 gccattgttg aaaaaggagc catgctttat catggagtga cgcttggtgg aactggaaaa
     3541 gatcgaggga agcggcaccc tactgttcgt gagggggcac tgatttctgc ccatgctcaa
     3601 attatcggtc ctgtcgagat tgggaaatcg gctaaggttg gagctgcagc tgttgtgttg
     3661 actgatgtac ctgctggcgt gacggtcgtt ggcattccag cccaaattgt tcgagtgcat
     3721 gagaaaaagc cctcaaggca ggattaatag ttttctctag aggcagtcag ccaaaaaacg
     3781 ggagagttag agccctatgc ttacctcagt tgctgacagc ttgcgcagtc taggagaaaa
     3841 ggataaaaac aaaagggaaa agtgatgata aaaatctatg ataccatgac cagaagtctg
     3901 cgagagtttg taccaataac tgataaggtg gtcaatatgt atgtctgcgg gccaacggtt
     3961 tacaattata ttcacattgg caatgcacgt tcggctgtgg cctttgatac gattcgtcgc
     4021 tactttgaat acgcaggcta tacagtcaat tacatttcaa attttacaga tgtagacgat
     4081 aagattatca aggcagccaa ggaatcaggt gtatcaccca aggaattggc ggacagattt
     4141 attgctgcct ttatggagga taccaaggca ctcggtgtga agccggccac caaaaatcca
     4201 cgcgtcatgg actatatgga cgagatcatt gcctttatcg ctgctttaat caaaaaaggc
     4261 tatgcctatg agtcggcagg tgatatttat ttccgcgtgg caaaggcatc aaattatgcc
     4321 agactggcta ataaaacgat tgctgatttg gaggctggtg ctagtggtcg tacagatacc
     4381 gaaactgctc tcaaggaaga tcctttggac tttgccctat ggaaatcagc aaagctaggc
     4441 gagatttctt gggcaagtcc ttggagcgcc ggtcgtcctg gctggcatat cgagtgctct
     4501 gtaatggcaa ccgagctttt gggagatacc attgatattc atggtggtgg cgcagacctg
     4561 gaattcccac accataccaa tgaaattgct caatcagaag caaaaactag caaaactttt
     4621 gccaattact ggatgcataa tggctttgtt aatgttgaca acgaaaaaat gtctaagtca
     4681 ctgggcaact ttgtgactgt tcatgatctg ctaaagacgg tggatgggca aacgctacgc
     4741 tttttcttgg ctactcagca ttatcgtaag ccgattaatt ttactgaaaa agctattcat
     4801 gatgctggag ttaacctcaa atacttgaaa aacacgcttc agcagcccac agtagccact
     4861 gcagatgcta gccagcttgc tgcctttatc actgccttca aagcagccat gaatgatgat
     4921 tttaatacag caaatgggat tacagtctta tttgacatgg caaaatggat taactccggc
     4981 gcctattctg aggctgtcaa atcagcattt gaagagatgc tagctgtttt tggcattgtc
     5041 tttgaagcag aaagcctaga cacagagatt gagcagctga ttgctgagcg tcaggaggca
     5101 cgtgccaatc gagattttgc aagggcagat gctattcggg atcagttggc agctcagggg
     5161 atcaagctgt tggatacaaa agaaggtgtg aggtggatac gtggctaatt cagttgatgt
     5221 caatttgatt aatggcattg cccttgcctt tgttggtgat gctgtttatt cttactatat
     5281 tcgtcgtcat ctgattttcc aaggccagac caagccaaat aagctccact accttgcaac
     5341 aaaatatgtt tctgcaaagg cacaggcttc tctgattcag gccatgctag aagcacaact
     5401 attgaccgaa aaagaaaaag acatctacaa acgaggccgc aataccaaca gccataccaa
     5461 ggctaaaaat gctgatgtag taacctatcg tatgtcaaca ggctttgaag ctattatggg
     5521 ctaccttgat atgacaggtc agacagaacg gctagaactg ttgatccagt ggtgtatcaa
     5581 gcaggtggag aacagtcctc aatcataatg atgaatcatc taaaacattc tctgtgtcac
     5641 tagcgatctg ccatcgctca aagtcatgag agtgttttta tgttgtgttt aaaagttatg
     5701 tcacaatata gatacacacg aaacataaaa taaatatttg taacaaaaac gtaacaaaac
     5761 tattgaaaaa ttttccgaat agtttataat gaaagagtca taataaaatg ataggagaat
     5821 gtctatgaaa ccaatgagaa acgtagcctt agttatttca gcaatgttac tgttaagctc
     5881 acaggccttt gtatcagcag tagcagcaca ggacaatcaa ccaaccatag cagttcaagc
     5941 acaggcagca gctgaggcca atgtcagtgc tcgtatgcgt tcagatcagc ccgttattga
     6001 agctaacatt gctaccagtc agccagttag ccaaagcact gaggctacta ttttactaaa
     6061 ggatgccaaa ggcaacgcga ttaatagcac agcctatacc atgcaggctg gtcaaagccg
     6121 gttttcagta tggtttgacc ttacgaacct aaaggttagt gattatagta tatcagtgag
     6181 tgttcctgat aaagaaaagg cctttagtgg tagctcagca cctattcatt ttgatggaaa
     6241 gccaaccaaa aataccccag agacagaaca gaaaaacagc aatccagtac cagctaataa
     6301 ccagcctaaa cccgctgcta gcggcagggt gacaagcact gagcaacccc aaaatgtgcc
     6361 tagcgcgact gctagcgcca atcatatgac aagaaccaat catcgatctg ataaggtcct
     6421 aaaggcaagc tcaagcaaca caccatcagc tgccaaatca atagactctg ctgagaaagg
     6481 caagggcatg ctttctgata gcacagccca agataaagag caaaaaggct ttccttggct
     6541 gctatcatct ctaattgcaa ttacagcagc tgctttactt gctcttgtca tcaaagctgt
     6601 tcacaggaaa taaaaagagc agcaagagct attttattgc tttcgtggta taataaaaac
     6661 catgaaagct aaagaaatca atgaaaccaa ggatattgtt tatggcgtcc atgccgttac
     6721 cgaaagccta ctagccaata ctggaaataa gctttacatt caagaggatc tgtgtggtaa
     6781 gcatgttgat cacatcaagg atttagccac tagtaagaag gtgtctatct cttggacaaa
     6841 aaagaaagct ttgaccgaaa tgacagcagg agctgttcat cagggctttg cgcttcgagt
     6901 gtcagccttt gcttatactg agctagatga gctgctagag ctggcacagc aggaggataa
     6961 tcccttgctg ctcatcctag atgggctgac agatcctcat aattttgggt ctattttaag
     7021 aacagccgac gcaacaggtg tttgtggtgt gattatccct aagcatcgtg ctgttggtgt
     7081 gacaccagtg gttgctaaga cctcaacagg agctgttgag catgttccaa ttgctcgcgt
     7141 gacaaatctt agccaagcat tggatcagct aaaagcaaat ggcttttggg tcttcgggac
     7201 agatgtaact ggtacaccat catacaagtg gaatacctca ggcaagctgg ctttgattat
     7261 tggcaatgag ggtaagggca tttcagctaa catcaaaaaa caggtagatg aaatgattac
     7321 cattcctatg atgggtcatg ttcagagctt aaatgctagc gttgcagctg ctattttgat
     7381 gtatgaagta tttagaaata aattatagat gaaaaaaaga ctattgctgg ttgatggcta
     7441 taacatgatt gccttttggg aatcaactcg tcagtttttt aagacaaacc aattggatca
     7501 agctagaagg atcttgctaa ataagctgaa caactatgcg cattttgatg atagtgacat
     7561 tatttgcgta tttgatgctc agtatgttcc aggacttaga cagcgttatg accaatatag
     7621 gatttctgtt atttttaccg aagaggaaga aacagctgat agctatattg agcggactgc
     7681 tgctgagcta aacaccgctc taaccatggt agaggtggct actagtgatc tgaatgaaca
     7741 gtggacgatc ttttcccaag gcgccttgcg tgtcactgct aaagagcttg agcagcgtgt
     7801 taatgctgtt aagtcggatt tagataagct gtcacaggat attgatctta aaaagcctag
     7861 actgggtccc tttgatcaag ggcagcttaa tcagctcaag gactttatga atcgattaga
     7921 tgattaataa gcttatcttg ctagcttttc taggtatgat tctccaggct gctagagcag
     7981 ctcatacgat ctaacggtga tcatttctga ggcagctggt tcttattgct ttcttagctg
     8041 atattttttt gttatactat gagaaaatca tttgattatt aaacgataat gacgttactt
     8101 gggagttcag atgacatttg tattgatgac agattcaaca gcggatttag gttctttttg
     8161 ggcaaaggag cataacatcg atatagtagg cctaactgtt gaatgtgatg gcaaggttta
     8221 caagacggtt ggtccagata gattaacgag tgatgctttg ctagctatga tgaaaagtgg
     8281 gagccagccc aaaacaagcc agataaatgt tggtcagttt gaagagattt ttcgacatta
     8341 cgcagctgat aaccaagctc ttttatatat cgccttttct tcagtcctat caggtaccta
     8401 tcaaagtgct gtcatggcac gtgagctggt tttggaggac tatccggacg ctgtaattga
     8461 gattgttgat agcttggctg cagcaggagg agagggctat ttgaccatgc tagcctcgga
     8521 ggcgcgtgat aatggaaaaa gcctattaga aaccaaagcg ataatagaag gtattttgcc
     8581 tcgcttacgc acctatttct tagtagatga tctttttcat cttgtgcgag gaggacgctt
     8641 gtcaaaaggc tctgctttta taggcagcct agtgaatatt aagcctctct tatggattga
     8701 tgccagcgga aaattagttc ctattgccaa gattcgtggc cgtaaaaagg ccattaagga
     8761 aattgctgac agagccacaa aagatattgc tgattcaact gttgttgtgt cctatactag
     8821 tgatcagact ggggcagatg acctacgaga acagctatta gcacatgaag gtatcagtga
     8881 tgtctttatg ctgccgctcg gaccggtgat tgctgctcat acaggtccag ataccttagc
     8941 ggtctttgtc atcggcaagg aaaaaagata aaaagaaaag gattgaagcg cttgtttcaa
     9001 ttcttttttg tcgactatag cttgttttag ctgtgatgcc gcttaagagt atgggtgttc
     9061 gcatttttta tttttaatca aaagttagaa tgaattgttt gacaatgaag gtgcgcgtgc
     9121 aggtaaggaa ctagcataac agaacagggc tttttgattt gccagaagtc agatgtcaaa
     9181 tgttttagca gttgacagga gctttggtca ttccaccact aatctttgta ttgttatttg
     9241 cataggagct aacaggaact gagcggattt tttggaggga agtcaaggct aatagtccag
     9301 ctcaaaagca agcctgttct tcttgtgaaa aagcaaaaat aatcaaagaa atagagctaa
     9361 accacttgac tatcagttaa gaagtttgat actatagtag acggtattgt ttaccccatt
     9421 tgaaaggccc cggaaccttc caaatacctt cgatggaccg gaacatccat cactaatgta
     9481 aacaaaaacg aattcgtata ggagaaatca tgaacaaaac aactttcatg gctaaaccag
     9541 gccaagttga acgcaaatgg tacgttgttg acgcaacaga tgtgccactt ggacgccttt
     9601 ctgcagtagt tgctagcgta cttcgcggaa agaacaagcc aactttcaca ccgcacactg
     9661 atacaggtga ctttgttatt gttatcaatg ctgagaaggt taaattaact ggtaaaaaag
     9721 caactgataa ggtttattac actcactcaa tgtacccagg tggcttgaaa tcaatcactg
     9781 ctggtgagct tcgctctaaa aatgccgttc gtttgattga aaagtcagta aaaggcatgc
     9841 ttccacacaa cactcttgga cgtgcacaag gtatgaaatt aaaggtcttt gttggcggtg
     9901 agcacactca tgctgcacaa caaccagaag tacttgatat ttcaggactt atctaagaga
     9961 aaggagcatt aaataatggc acaagcacaa tatgcaggta ctggtcgtcg taaaaacgct
    10021 gttgcacgcg ttcgtttagt tccaggtact ggtaaaatca ctgttaataa aaaagatgtt
    10081 gaagaataca tcccacatgc tgacctacgt ttagtcatta atcagccttt tgcagtgact
    10141 tcaactgaag gctcatacga cgtttttgtt aacgttgtag gtggtggtta tgctggtcaa
    10201 tcaggtgcga ttcgtcatgg tatcgctcgt gcgcttcttc aagtggaccc agatttccgt
    10261 gactcactaa agcgcgctgg tcttcttaca cgtgacgcac gtatggttga acgtaaaaaa
    10321 ccaggtctta aaaaagcccg taaagctagc cagttctcaa aacgttaata tccagttata
    10381 ccaacgtttc agagcacttt gcgaagtttt cgcaaggtgc ttttttgttg aaaaaagcac
    10441 cttggtaatc tgttgagacc tagttttaag agaggttaag ttagaatgac tataagtatc
    10501 taaagtcatc tggctgctag catgacctag acgcttagcg gtattaactg ggtcaattcc
    10561 catttcaatc atcaaggttg cgtgagtgtg cctaaaccca tgtgggctaa tctttttaag
    10621 attatgcttt cgtataatgc gttttagaat attgttgata tagtcagcgt gtaagggttc
    10681 tatctcacca tctctgttgc agtatgtaaa cataaattct ttgtcgagag aaaggggctg
    10741 tactgataat tgcccctttt ctttgctagt ttcctgtttc catttgttga ggatagaaca
    10801 ggtttcatca tcaagataga tagagcgtac tgagaatgta tttttagttc ctttttcaat
    10861 ggcatgacca tctattcttc ctaaactttt gctgactgtt aatagttgat tctcagaatc
    10921 aaaatcttcc catttgaggg cgtagagctc tccttttcgt aacccgctgt atgctagtaa
    10981 tcgaaataga gcataatgtt tataaggttc attttctaaa atgattgtca aaaaatgatg
    11041 caactcgtta actgtccagt agttctcact gacagttttt ttgagtttag gcataataac
    11101 tttgctcata ggattacgtt caatatgatt catattgatg gcaaattcaa aggttttaga
    11161 ggtgtatgac ttgatttgct tcatgttctt gaatgatttc gctttatctg tgataaaggt
    11221 ttggcagtct agcggactga tttttgaaat ctttttctct ccaaaggttg gaagaatatg
    11281 aaggcgatat aaatcggccg ttttagctgc agtagttgtt tcaacggtat ctttgtaagc
    11341 ttcataccac ctttgatata gttcttggta agtataggtt gtttgagcag taagatgggc
    11401 aaaagttcca ctattcagct gatgattaac agcagtttca tgagctttgg cagctttacg
    11461 cgtcttgaat cctcgtttag tgtaatattt tttcttaccg tagtcgttta gaccaaggta
    11521 aactttaaca aaataggtaa ttccttttgt agattggtat ttgtgtacag acataacagt
    11581 tctccgtttc taagttttcg gagcttatgt aattgagaaa tattagtcta ttttctgtca
    11641 cgatctgctc gtctaatttg aaactcttcg gtttgtatcc atgttttcca aatatccgat
    11701 ttttggcctt ggttattcat aaacttaatt aagtctttga taaaggtttc ttcataatcc
    11761 attaagtagt tagaaagaat acgtctaaag tcatctgaga aaacctcgtt taagggcata
    11821 gacaaatgaa tctctcctag ttcgattcct ttcttaagct tctccatatc gcttttaaaa
    11881 ggtgttacag aagtaatttc agatgtcttg aaactatcag tgacgatttt taaatttgac
    11941 ggagcgtact tttcttcgtc aattccaagg atgtatgcca ctgagacacc aaaataatcc
    12001 gctaactttt gagcattctc ttttttaggt tttcgtattc cttggttata gctagatagt
    12061 gttgggtagg atatatctag cgcttcactg atacttttta tttttttgcc actttcttct
    12121 ataagtttag ctatattatt agtcatagat tcctcctaat tgatattcta ccacatttaa
    12181 tacaaaaagt ataataccac ttgacaagaa tacaaaaagt atttataatt taaaatgtat
    12241 aataaaatat acaaatttcg gagtttattt aattgagaaa tggaaacgag gtaatgatat
    12301 gtctgaagaa gcgactttag ttgttcaact tcccaaagtt ttggaaaaac aattaagggc
    12361 acattatgat gaaatggttt ctacagctat tgaaagagcg ctagaggata aagaattata
    12421 taaacctatg gttcggatgg cagccctttc tagatggctt gatgtgtcaa cgacaacact
    12481 tcaaaagtgg acgcgagaag gaatgcctac aatggttatt gatggtgtga ctctgtacga
    12541 taaacgtgcg gttacacgtt ggttgaagca atatgaaaga tgaggtaaag aatggctaat
    12601 agacgaatgt tgagtaaaac ggtggtgcag atacaacgat ttttacgcct accacttgaa
    12661 gcgcaggcgc tttactgtca cttggtagtc aatgcagatg atgatggtat tgttgaagct
    12721 tttcctgtta tgcggatgat taatgctaat gaggacagtt tgaatttatt aactcttaag
    12781 cagtatttac tcttgttaaa caatgaaatg gtttacttta tcaaggattt ctttgagcag
    12841 aataccatca aagcagatcg ttacacaccg agtagtcatc gtcaacttct tatagattat
    12901 ctgaaggata atcagttgtt ggagtgtcta aatctaggac cacgcttgat taattatctt
    12961 caaaatactc ggctccaagt tggagccagt ctggatccag atgggaaccg caatataatt
    13021 aaagataaga taagtaaaga taggataggt aaagataagt taagtcaaga taagatagga
    13081 ttagataatg atccaatctc atcacaactg actgatgaca tctggttaat ggaaacacta
    13141 tggcatcgag aattaaccca acaggagaaa gtattattag aaggattcgc ggttaatgat
    13201 tctttattgc agttagctat tcagaaaaca gaggagcttg agccaaagaa acaaaacatg
    13261 agttatgtca aagggatact aatgaattgg gaagctagag ggtttataac tgttgaccaa
    13321 gtgatagcat ctgaagaaga ctaccgtcca ttagaaattg caaatgtaga agtttcagaa
    13381 gatttcttag cagctatgga tatatggaaa gactagggga ataatgagtt atgacagtat
    13441 attatcaatt agaaaatatg ttagtggctg ggtttaagtc acaagatgag tacgaccgct
    13501 atcaggctct caagagggac tatgaagggg agtcagagga ctatagcttt tcaatcagag
    13561 aaatcacaaa tcaacttgaa atcatttgtc agacctcaga gaatgatttt ccgaacttat
    13621 cagaagcatt aatgattgat tatttagaac tggtaggaga gttgaaacga tatgatacta
    13681 atcaggcaga caggtattta gggatggttc gtcatgtctg aacgtatcag aactatttta
    13741 aagaagtttt atgtgacgga attgcagaat gaagtactta atcaactagt aaatgataca
    13801 ggcttgcaaa cattctctaa ttatgctcgt cggatgcttt ttaaggaaac atcactcttt
    13861 atgcgatttg atgaatctca gtttgatgag ttgatttatt ctttaaggcg tattcaaaat
    13921 aatttaaggc agttatctaa aattgcagag cagtctcaag atagtcaagc ctacagagct
    13981 atggactata gcagaaggtt agtttcacat tatgaaaagc agttaacgcg ttaccacaag
    14041 aaaaagaaac ggaaattatt atctaaggga gcttaatgga taaaaggaga attaggaacg
    14101 taattaaaca agtctttttg tctgaagaag aaaatcaaaa actgttagag aaaatgaagc
    14161 aagatggctt cacaaacttt tctctttttg ctagaaagca attattaaaa cctgattttg
    14221 aaacttggct agttagtttt ccagaatatc agccgctgac tggcaggtta ctatctgttg
    14281 gtagaacaat taatggcatc gctaaaagcg caacacagtt tggaaaaatt tcccaacatg
    14341 atttgatgga attaggtcag ttgatggagg aacttgtaga actggtagag aaacaagtga
    14401 aggaagacaa gcaacgaata gccaagaagt gatagtcgtt cagtcatttt ggtagaatag
    14461 ttttaaataa aacaacaaaa acgctgatgg tagtcagcgt tttttagcat gtaattgtaa
    14521 aaaatccttg tacggacaat gtgcggcacc gtataaagta cgggaaatca ctaaaaatgg
    14581 agttaggtct ttgcgagctc agatagtgta tacacactat cgtaaaaata gaaccatcag
    14641 taaaggtcag actgacactt tttgattgat gcttatattt tattttgggg caaagcccca
    14701 aaccccttga gaaaacgtgt gagaagtagg gaaaaatggt ataatagaaa tattaaagac
    14761 tgtgaggatt tgaagatgtc agaacaagca caaaggcaag agttgcaccg caaaatctgg
    14821 gcaatcgcag atgatgtccg tggtgcggta gatggttggg atttcaaaca atatattttg
    14881 ggaatccttt tttaccgttt tatcagtgaa aatttcaaga cttatatcga gggtggtgag
    14941 gacttcaact atgaggagat tccggatgaa gtaatcacac ctgaggttaa ggatgatgcg
    15001 attaagacaa aggggtactt tattatgcct gcgcagcttt tttccaatgt tgtgaaaaca
    15061 gctcgtagta atgacaactt aaatacggaa ctcaaggata tttttgatgc cattgaggcg
    15121 agtgctatgg gttatgccag tgaaaatgat attaaaggtc tttttgatga cgtagacacc
    15181 agaagtaata agctaggaag taccgtccca gagcgtaatg aacgcttagc ccttatccta
    15241 gaaggtattg ccagccttga ttttggtagt ttcgaggaca atcatatcga cctttttggc
    15301 gatgcctatg agtttctgat ttctaactac gcttctaacg ccgggaaatc aggcggagag
    15361 tttttcacac cgcagagcgt gtcacggctc ctagcacgta tcgtcatgtt aggcaaggat
    15421 gaaaagaaca aaatcaataa gatttatgac cctgcttgtg gttctggttc tctcttgctt
    15481 caagccaaaa aacaatttac ggagcatatt atcgaggatg gtttttatgg tcaggaaatc
    15541 aacatgacca cctacaactt ggctcggatg aatatgttcc ttcataatat caactacgac
    15601 aagtttagca ttgagcgtgg caatacgctg ctggacccta agcatggcaa tgataagccc
    15661 tttgatgcta tcgtgtccaa cccgccttat tcaatcaagt gggttggtag cgatgacccg
    15721 acgctaatta atgatgaccg ttttgcacca gcggggattc tggcacccaa gtctaaagcg
    15781 gattttgctt ttatcatgca tagcctttct tatttgtcca ataaaggcag agcggctatt
    15841 gtgaccttcc ctgggatttt ttatcgtggt ggagcggagc aaaagattcg tcagtatttg
    15901 gtagacggaa actttgtcga aactgttatc caattgccgg ataatctcct ttttgggacg
    15961 tctatcgcta cctgtatcct tattcttgct aagaataagc cgacaacaga tgttctcttc
    16021 attgacgcta gccagcagtt caaaaaagaa accaataaca atgtcttgac agaagagaac
    16081 atcgagaaaa ttctgaaaag tgttgagcat aagaataatg aagagtattt tgctcagctc
    16141 atttcccaag aaaaaattgt ggaagctgac tacaatctct ctgtatctac ctacgtggaa
    16201 aaagaggata cgcgtgagaa gattaatatt gatgtattaa acaaagaaat tgctgagacc
    16261 gtgaaaaata ttgaccgatt gcgggcagag attgataaga ttgtcgagga gttgagctga
    16321 tatgacctac attgatgaga tgattaaaga gctttgtcct gacggagtgg agtggaaaga
    16381 gttgggtgaa gtcgttgact acgaacagcc aacaaagtat atcgtaaaat ctaaggaata
    16441 cagcgatgat tattccattc cagttttgac agcaggtcag acatttattc ttggatacac
    16501 aaatgaagta actggtattt atccagcaag taaggaacat ccagttatta ttttcgatga
    16561 ctttacgaca gctagaaagt gggtggattt tgaatttaaa gttaagtcct cggcgatgaa
    16621 actactctct atcaagtcag accgtcaaga tgatgtttca ataaggtatg tttggcacta
    16681 tttaggaaca ataaaataca caccagaaca gcacgcacga cagtggatag ggactttttc
    16741 taaatttaaa atcccccttc ccccactaga aattcaaggg gagatagtta aaatacttga
    16801 caaattcacg gaacatgtta cagaattgac cgcagaattg accgcagaat tgacctttcg
    16861 acagaaacaa tattcttatt ttagagataa gctcctaagt tttgatgatg aaagtatggg
    16921 aggggcgaac gataaggttt acactgtcca gtggaaaacg ctgggggagg tggtgaattt
    16981 taggagaggg tctttccctc agccttacac agatatgtcg ttctatggtg gagaagatgc
    17041 ccaaccattt gttcaagttg tagatgttgc tgatgaagga tttagactga atactaaaac
    17101 gaaaaaaaca atttctcaaa aagctattcc aaaaagtgtt tttgtaccta agggaaccgt
    17161 tatcgttacc ttgcaaggca ccctaggaag ggtagcggtt acccagtatg atgcttatgt
    17221 cgatagaacg ttagcaattt ttgacggtta taagcaagaa gttgataaac gctatttcgc
    17281 acaccaattg aagtttattt ttgacagaga aaaagaattt gctagaggaa gtactctgaa
    17341 aacaataaca aaacaagaat tctcgaattt caaaatccca gtccctcctc tggatattca
    17401 gcgtcgtatt gtccaagttt tggataattt tgatacggtt tgtaatgacc taaatatcgg
    17461 gctacctaag gagattgagc ttcatcagaa acagtatgcc tattttagag acaaactctt
    17521 gaccttcacc gccgaaggcg tgtatactga cagtacagta cagtacagta cagacaagac
    17581 ctaattaggc tcttgacttg ggtttttgga ccgattaagg ttgagttggg ggctgtctgc
    17641 gatgtggtgc gtgggaatgg tttgcaaaag aaggattttg ttaatgaggg ttatcctgtt
    17701 attcattatg gacaaatcta taccttctat ggattgagtg ctcgcgtgac gaaatctttt
    17761 gtgtcaccag aagttggtca aaaattgaaa aaagctaaaa ctggtgatgt gattgtagct
    17821 actacttctg aaaatattga agatgttggt aaagcacttg tttgggaagg tgctgaagat
    17881 gtttgtattg gtggacactc ttgtgtattg cacacggaac aaaactcgaa gtacttgctt
    17941 tattattttc agacaactgt gtttcaaaag caaaaggaaa agttagtgat aggaactaaa
    18001 gtgattgaac tgtatcctaa aaatttagaa aaggcgatta ttattctccc acctgtatac
    18061 gaacaagggc gtatcgtctc cattcttgac aaatttgata cactaacttc tgaccttacc
    18121 caaggtcttc cgaaagaaat tgagcaacga cagaaacagt atgagtattg gcgggattta
    18181 ctacttaact ttccgtagga ggaagaatag atatgggaaa tgatatcaaa tttgaaaatt
    18241 tagaacagat ttcggataat attatttcta gtaataagaa agttcatttg ctatatgcct
    18301 ataatgctac tgggaaaact aggctttcta tggaattgaa aaataaggta aatgagactg
    18361 atagtgatgg taatagcatt aagcacattt tatatttcaa ttcatatacg gaggatcttt
    18421 ttacgtggga taatgatttg gaaaacgatg aagatcgata tttgatttat gataaacgaa
    18481 cttattttgg aaatttcctt gaagagcaac aacttttcga acgtgctgta gacaattttc
    18541 aaaagtatgt tggtagatct attgatattg agttccaaga tgttattgaa acagttaaag
    18601 atgagttcgg aaatgttcaa aaagataata ggggtgaggc actaacaatt agtaataaaa
    18661 agagtataag atttaaagta gatgggcata caataaaggt gtctagagga gaagagagga
    18721 tttttgtttg gtcagttttc ttaacgctcc ttgaaattat tattgaagat ttgactgagt
    18781 ctgctgatac ctcagaattt tcaaaaatga actatatcta tattgacgat cctatatctt
    18841 ctttggatga tactaatatt attaatgctg caatttattt gagtgatgtt ataggtagtg
    18901 ctgaaaatac tgatttgaaa tttgtcgtct ctactcatca agcattattt tataatgtac
    18961 tttataatga aatccgattt gatagaagaa tcaagaaaaa ggttttttac gtcatgaaag
    19021 ctactgatga aattgaggat gagaaacaat ttaaatattt gttgacagat gttgaagggg
    19081 attctccatt tggatatcat ctcagagtga gagaagaatt gagaaaagca attcaagatg
    19141 aacaggtaga gaaattccat tttgctcttt ttagaaacct agttgaaaaa acagcaacat
    19201 ttttaggata tggacgatgg gaaaatatct tgttaggttt agatgttgct ggacatgtta
    19261 taacatctga aaatattaaa ctctatacac aactgattga tttatacact cataataggc
    19321 atgctgattt agaatataga gaattgcctc cccaagagaa aaatactctt ataaatttat
    19381 ttaatagctt tgattcaatc tatcgattta aagaggacta actatgactg aaatcatcca
    19441 aacagatact attttagagg ctaagaactt cattgtactg gaaaaataca ccaagttgga
    19501 aaagcctagc acctatcaga cggaagcaga cttggagcga gagctggtta gcgatttgcg
    19561 gcagcaggga tacgagtacc tcaacaatct gacgacccca gaagctctct tagataacct
    19621 aaagacccag atggaagccc ttaatggcgt ggttttttct gaggcagaat ggctgcgttt
    19681 tttagaggag tacctcaata agcctagtga tggtttgatt gaccgcaccc gaaagctcca
    19741 cgataaccac atctacgact ttatctttga cgatgggcat atccaaaata tttatctctg
    19801 ggataagaaa aatatcagtc gaaataagct tcaggtcatt aaccaaatgt ctcaagttgg
    19861 gacttcaagt aaccgttatg atgtgaccat tttggttaat gggctaccct tagtacaaat
    19921 tgagcttaaa aagcgtgggg tggctattcg tgaggctttc aaccaggttc accgttacag
    19981 taaggaaagc tttaatgagg aaaattcgct cttcaagtat ctccagattt ttgtcatttc
    20041 aaatgggacg gatactcgct attttgctaa taccactaag cgagagaaaa attcttttga
    20101 ctttaccatg aattgggcac taaaaaataa tgagccaatc aaggatttga aggattttac
    20161 agcgaccttc ttcagtcagc agacactctt aaacattctc atcaactact cagtttttga
    20221 tactagtgat accctcctaa tcatgcgtcc ctatcagatt gctgcgacgg agcgcatcat
    20281 ctggaagatt cgttcggcca ttgatagcaa aatcaagagt ggtcctgaga ctggcggcta
    20341 tatctggcat acgacggggt ctggtaagac cttgaccagt tttaaggctg cgagactggc
    20401 gactgagatg gataaagtgg acaaggtttt ctttgtggtt gataggaaag acttggacta
    20461 ccagactatg aaagaatacc agcgtttttc acctgactca gttaatgggt caaatagcac
    20521 agctggactt aaacgcaata tcgaaaaaga tgacaataag attgttgtga cgacgattca
    20581 aaagctcaat aactttatgt ctagtgaagc acagcatgag atttacaaca agcaagtggt
    20641 ctttatcttt gacgaatgcc actgttcaca gtttggcgag gctcaaaagc gcttaaaaca
    20701 aaagtttaag aagtattgtc agtttggttt tacaggcacg ccgattaaag ttgaaaatgc
    20761 tttaggcagt gagacgacag cttctgtatt cggtcgggag cttcatgcat acgtcattac
    20821 tgatgctatc cgtgaccaaa aggtgttgaa atttaaggtg gattataatg atgttcgtcc
    20881 acagtttaag tcgttagaaa ctgagcaaga tttagggaaa ttatctgctg ctgaaaataa
    20941 aaaagcccta cttcatccaa cacggattac agagatttcg gcttatattt tagaacattt
    21001 taatcaaaag acacataggc aaaacggtaa aggatttaac gctatgtttg ctgtgtcaag
    21061 tgtcgaggcg gccaaggctt actaccaaga gttgcaagac caacaagctg gaaaagctaa
    21121 accattgaag attgcaacca tcttctctta tgcagcaaat gaggagcagg ctgcgattgg
    21181 ggagattgat gacgagactt tcagccctgc tgacttgtca gatattagta gtaaggaatt
    21241 tttgagcgga gcgatttccg attataatcg cctttttcag actaatttta gtatcaatgg
    21301 caatgagttt caaaactatt accgtgattt agctaagcga gttaagtctg gagaagtgga
    21361 tttgctgatt gtcgttggta tgtttttgac tggttttgat gcaccaacct tgaatactct
    21421 ttttgtggat aaaaacttgc gttatcatgg gcttattcag gctttttctc ggacgaatcg
    21481 gatttataat gcgacaaaga catttggaaa tattgtaact ttccgtgatt tggagaaggc
    21541 tacgacggat gctattaagt tgttcgggaa gacggagacg gctgatattc tgttagagcg
    21601 ctcttacgag gactacatga atggctacat tgaggctggt caagagcaaa aaggatattt
    21661 ggaagtcgta aaagaattgc aggagagatt tccagatcca acgactatta tcaaagaaag
    21721 tgataagaaa gaatttgtga ccttgtttgg tcagttcttg cgcttggata atatcttgca
    21781 gaactatgat gatttcatga gtttgcaggc tttgcaagag ttagatgtta cagatataga
    21841 ggctttggca gatttcaaag gacgttttca tttggatgac gaagcagttg cagtactctc
    21901 tcaactggac atcccaagtg ttcgtgagat tcaagattat cgctccgctt acaatgatat
    21961 caagtcttgg tatgacaatg agcggcgtaa tcagcagaat aacgattccg aaatcgactg
    22021 ggatgcggtt gtctttgaag tggagttgtt gaaatcacag gaaatcaatc tggactatat
    22081 tctggaattg atttttgaaa ccaaccaaaa ggtatctgac aaggatcaac tcattgaaga
    22141 aattacacga actatccgtg ctagtctggg tcagagagct aaggaaagtt tgatcgtgga
    22201 ttttatcaat gccagtgact tggacagttt ttctgagaag tcagatatct tggagcaatt
    22261 ttatacattt gcccgtcaaa aacaaaaaga agcagtggct aatttgattg agactgaggg
    22321 attgaatgta gagagtgcta gccgctatat tcagatgtca ctcaaacgag agtatgccag
    22381 tgaaaatggt aatgctctca atgaagcact tcctaagatg agtccgctca atcctcaata
    22441 tcgtaccaaa aagcagatgg tgtttgaaaa aattgtggat ttggtggaga tatttaaggg
    22501 gattggtgga gaaatttaat tattattatt tcttctagat atagaagaga taaactttaa
    22561 attagagctt gaaattttaa gaaatattaa ggcatcatat cagtagtata aaaagctgac
    22621 ttataattta tttggaaacg acagttaatc ctaaaatacg atgcttgata tggaggaggc
    22681 ttaaacttgg aaaataaaaa ggatttaatt caaaccttag cctactacca attctcacta
    22741 gaaaaccaat acttggatag aaaatcagca cgaaagaagc cgcaagaatt actcaagcat
    22801 ctgattgctt ttgccaatgc ggacggcggt cagttggtta ttggtattga agatgagaag
    22861 caggacaata ttatcactgg tttcaaggat ggcagagctt atcccataga cgatttcaaa
    22921 aaaattgacc atgagatgcg ggagactcct ctggatttgt ctttagagga aatccctgtg
    22981 ctaaatcata agggagaaga tgacctgatt ttggttattt ctgttgaatt atcgtcgaac
    23041 cgagtgattg ctgcgcctaa tgatgaggtt tatctgcgtc agggcgatga atcggttaaa
    23101 ttaagctatg agcaacgtac tcagcttagc tatgataagg gccaacgttt ctttgaagat
    23161 gaagtggtac ctgatgcgac cttggaagat attgatgatg ggttagtcca ggacttcaaa
    23221 aatcggtttg atatttcaga gcgctccatg gaagaagttc ttaaagcaag acgattcttg
    23281 gttaatggta aattaactaa ggcagcgatt ctactctttg ccaaatatcc atcagcgttt
    23341 tttccacaag ctcgtgttcg ttttcaacgg tttgacggga cggatatggg aacaggcagt
    23401 agctttaatg ttattaaaga agtaactttt gatgatgctc tgcccacctt aattatcaaa
    23461 gtgcgagatt ttatccgtac tcagctgcgt gaatttcagt acttagacga taatgggcaa
    23521 ttccagattt tgcctgagta tcctgaattt gcttggtttg agggtgttgt caatgcggtg
    23581 actcaccgtg attactctgt ctatggggat cacattcgtg tactcatgtt tgatgataga
    23641 ctggagattc atagcccagg gaaattacca aatatcgtta ccgttgacaa tatcaagcat
    23701 gaatgttttt ctagaaatcc tcggattgcg agaaccctga ctgaatttgg atgggttcgt
    23761 gagatgaatg aaggagtgaa gcgtatctat tctgagatgg aatcagcttt tcttcatgaa
    23821 cctaaatatt tagaaccagg taataaggta gttttgaccc ttgaaaataa catcgtgagt
    23881 cgacatctcc gaacacgaga tagtttggaa aaacaatttt ctgattttgg aaatctgact
    23941 gcagatgaac aagctatcgt tcactacatg tataattctg gcgataaaat gacaacagca
    24001 aaggcgattg agttgacagg gagaagtcgt tcgtttgttg tcaaaatgct acatcatctt
    24061 cgtgatttag aaatcatcac ttggtttggt tcaagtaaaa atgaccgtaa tcaatattat
    24121 cttttagttg ataaatgatt gcagccagga tacttattag taataagaat acagtagaat
    24181 acagaaaaag tggtgttcca taaaatattg atcaccactt ttgattatag aagtttaaat
    24241 aaagtggata tttgtatata gttcacaata tatacctcaa atacaataag aaatagtggt
    24301 tatatttttc tgttattgta gatatttaaa aatagttgat aagtgattac atttagcatc
    24361 tctcaactga taaattccga aaacatactt atttttagta aactaatggc aagtttgcaa
    24421 attgctttat attgctaagt cactattgat ttgttataat cttgttatac ataaggataa
    24481 cgcaattaag gagactataa tggctacatt aataagagat agacagtata attttagagt
    24541 aaatacggaa atgatggaag aagcaaagcg tattttagaa gctaaaaata ttagtgttcc
    24601 agatgctctt aatctatttg ttgaacgggt ggtggaagaa aaagatttac ctattaaaac
    24661 tgcagaacaa attagagctg aatcattttt aaatgaactg atatcagagc ttgatgaagg
    24721 gtatcaagat attttagcag gacgtacgaa gccagctaat gaggtatttt caaaatatgg
    24781 cttatgatat ctatatttca aataaggcag aacaagattt agatgaaatc tataactact
    24841 atttaacaga attttcgcac tcaagcgctc aaaaagttat tgaatctttg cagtcagcta
    24901 tttctattct tgagatatcc cctgaaggtt atgttgattt tgacgatcgt gtaggacgta
    24961 aactatttcc tgaaggccag ctaaggatga ttcctagtaa gcatttcata gtattttatt
    25021 taattcgtca gtcaagggta gatattcttc gtattagaag tactaaaact gattatttaa
    25081 atgatttaga gaatcttttt aacaatatcc tttaatgata gagtaagtat tgttttttat
    25141 gtaactattt aatcatgctc tgttatgacg ggatgatagt ataaagtgga tatataaaag
    25201 caaagtaaat acgagatttt ctcaactaca taagctccga aaactgagtt ttggtaatct
    25261 aatggtaatc tattatttgt aggattgggt taaaagtgct tatatttaat gaaaatgagt
    25321 tttgaaagct tgatttgata agcttttaca gatatttggt ttttgtcacc caaaaccagg
    25381 tcttaagaaa gctcgtaaag ctagtcagtt ctcaaaacgt taagaaccag ctacaataca
    25441 gcagaacaat acttcatggg ttaccatggg gtattttctt ttttgaaaga actggcgacg
    25501 caattgacgt agtcgttgcg gctttagtcg cttacgaata cggctgcaaa ggagacgcag
    25561 tctccgtgcc tcaaaacgtt aatatatcgc attatatcaa cgtttcaaag cactcaagag
    25621 tttacctcat gggtgttttt tctgtgcttt ctacgaaaat ggctctataa tttggctcaa
    25681 tgtcaactgc agtgggtgac tgatagctaa gcacgagaag agataaattt tgtctcttct
    25741 tttgtgatgt ttaaagcatt gggaatcttg actttgaagt tcttaaagtt cctaaatcca
    25801 aaggcttgct ctttcatgtc cttaatagtc ttgttagtgg gctccaattt agcattggaa
    25861 taaggcattt gtgatgtagg gtttgtattt caaaaagatt ttgaggacgg ttaaaacgtg
    25921 atgattgacc aagcttaaag ctcttcaatc agcccgaaaa actcggttac ccactttttg
    25981 aaaatgaaag agcaagagct ggtaaaggtc gtggtaattc cacagctcat ctgagaaatc
    26041 aagtattttc tgacttacct tttttgagta ttaaggtttg cttaaaggtt cgtgactaga
    26101 agcgctgatc agacagttta tgactgtcct tttggagcag tcatcaatga tattttatgg
    26161 ttcgataaag cagaaatggc tgctcaaagc ccttcataat ggctatcaat tctggcggtc
    26221 atcaaagctc gacccaggtg ctgaatgatg tgaaagtaat cccatacaat gctatcaaac
    26281 acttattgtc aatcaaaaga ggttgtctgt tccagcctct ttatactgtg actataagct
    26341 gctctcatcg gtcgaggata acgaggtcat tgaatactcg cgctccactt ttccgagcgg
    26401 gagttcaatc aaaaggttac tttttcttat ttggttggcc tgtaaatgga tcaatggtct
    26461 caaatgatgt cagttggttt gctaccctat cttcctatag tgatttgaaa tatatttggc
    26521 tatcgttttt agatttttac cagctgtgtc tccataatag cccatatacc aaaatttctg
    26581 atgcctatgt ttatgcttaa ggttggtgtc tttgtcaaaa atgattaggc tgctcttata
    26641 cttttaagta tctcataaag ctggcaacac ttcgtttagg aaaaagactt actaatgcat
    26701 agatgtagtc ggaacatgta ttcgctttgt gatgataagc tcttagcatt ccacatattt
    26761 ggtatgatgt tcctatatct actttgtaac gcctatagat aaaaagagga aaagaccttg
    26821 atgaatgaac tgatcctcgc ttgttagagt ttttggctaa cggttggggt gcaattcaaa
    26881 aaaatcaagg tcttgttatt tcattaaagc ttggctgtac ttatgttaat ctggcagatg
    26941 ctcataggct aggcagatag tgtagctttt ggtgcctcct tctttgagga taatgtcacc
    27001 aaactggttg tggtgaatag catcaggcag ggtttgtgct tccatagcga tcccctcacg
    27061 agccagtccc tccttgccct gatctcttcc aaaatacaag ccatcttgga tactgtccat
    27121 ggtataaatg acgagtgcgt ttcggtcaga gtagatgctg atttggtcat ggctgacgct
    27181 gtcttgtaag acagcaatag gtttggttgt tccaatagcc tgctgatcaa tttcaaaggc
    27241 agtatcaaag ccattatttt cgacaatagc aggatagagg gactttattg atctaaaatc
    27301 atagaccgtc tggtcaactg ctagcttttg acctgttggg attagctcat tatctgtttc
    27361 aatcctatgt gatgctgcga tgtataggtt gtgattggtt aagtcttgtg tttgccctaa
    27421 attaaaataa acatggttgg ttggattgaa taggctagtg cctctcatgc tatgagcctt
    27481 aaagtgaatg cttaaacgat tatggttgtc tagacggtag gtaatgctta cggtcaggtc
    27541 acctgggaaa tggtcatctg cttctaaaat atccctttta aaggttactt caaggtaatc
    27601 aactgtttgg cgggtatcat aaggccaatg aagcttatga aagcccttga agcctccatg
    27661 caggcaatgc ccattttcat tggtgtcaac acaaaccctt tgctgctcta gctgaaagct
    27721 tcctctcttt atgcgacctg ctactcggcc aatggtttgc cctgcacaaa gaggattttt
    27781 taggtagtca cttggtcggt catgtcccaa aatgatattt tttggctgct tttcatttga
    27841 cactagaaag gcctgtagag tggctcctag tgtcaatagg tgagcctcaa caccgttagt
    27901 attaatcagt cttagctggg tgactggcac ttgatcgatg tattcaatga tgtcttgata
    27961 aatgttcaca gtttgtttct cctattagta taggtgtatg aattaaggga ggctgactac
    28021 ttgctgtggt agctgtcttg agggactagc tgccacttgc tttatcgtca tatccttttg
    28081 gatgcttggt atgccaggcc caggctgatg cgattatctt gtcaatatcg tcatagcttg
    28141 gcttccaatt gagaaccttg cgtgcttttt ctgatgacgc aattaaggtg tctggatcac
    28201 cgggacgtct tgcagctttt ttggctggta tggcttgtcc tgttacccga cgagcggctt
    28261 caagcagttg acgattggaa aagcctgttt gagaccctag attaaagacc tgtgatggtt
    28321 tgccctgacg caggtatgcc atcgctaaaa tgtgtgcatc agctaaatcg ataggatgga
    28381 cgtaatctcg aacgttagta ccatctggtg tgtcataatc atcaccaaaa atcatcacct
    28441 gctcacgcac tccctgtgca gtctgtagga taatgggtaa taaatgtgtt tctggctcgt
    28501 ggtcttcacc gatggagcca tctggctttg ctccggcaac attgaagtag cgaagggcca
    28561 caaatgtgat gccataggct ttgtcggccc aggtcattat cgtttccatc ataagcttgc
    28621 tttggccata aggattgatt gggcatttag gcgctgactc taagatgggg actgtttttg
    28681 gaatgccata gacggctgct gttgatgaaa agacaatgcg cttaaccttg gcttctctca
    28741 tgacctcaag cagcttaatc atacctgctg tgttattgtc aaagtatttc agagggtctg
    28801 ccattgattc tgcgaccaag gaagaggcag caaagtgaat cacagtgtct atgtctggat
    28861 tgtccctaaa gacttgacgc ataaaggctt tgtctgctaa gtctcctttg taaaacagag
    28921 cctctgggtg aacggcttta cggtgccctg tcaccaagct atcaacaaca atgacttttt
    28981 cttctctctg tgatattagc cagtccactg tatgtgatcc aatgtagcct gcaccgccta
    29041 aaactagaac agtcattttt tcctcctatt cttcaattgc ttcaatgcca atgctcttaa
    29101 gaaaacgcat aaaggctgct tgaccttctt gatcacgttt gtagacgcca gcgtcctcaa
    29161 ggacacgaac aaagacagag ccgacctctt cttggataat gtcatcaaca gttatcgctg
    29221 agagatctgg tcgtaatgtg atctgatcag cccagtcctt gtggtagtct gcgatttgat
    29281 tggcttgatt gaggatatat tttttgacct caaccaattc ctctttgagg cgcggtggta
    29341 aaatagctag ccccataacc tcaataaggc cgatgttttc tttcttaatg tgttgcacat
    29401 cggcatgtgg gtggtaaaca ccgtctggaa attgctcaga ggtatggtta tcacgtagaa
    29461 ccaagtctaa ttcaaactgc ccttcttttt ttctggcaat aggtgtgatg gtatggtgag
    29521 gctcttggtt ggtataagcg acgatatcaa cactgtcgtc agaataatga cgccaagcca
    29581 gtcgaatcgt gtctgctaat tgaactagct gatctttgtt gctgctgcgc agtcggataa
    29641 ctgacatagg ccagttgaga gtggcagcct gtatgtctgg aaatccttta aaggtaaagc
    29701 gtttgtcttg ttttgcgatt tccatcggaa aaacgtgccg accggcctga taatggttgt
    29761 gggtcaaaat agagccgcca acaataggca gatcagcatt agagccgaca aaatagtctg
    29821 gcaggatatc aacaatatca aggagctgtc taaaggtgct tgtactgatt gtcattggca
    29881 catgctcagt attaaaaata atactgtgct cattaaaata agcgtagggt gaatactgga
    29941 atccccaagc ctcattgcct aagctcatac ggataatgcg atgattagct cgggctgggt
    30001 ggttaatccg tccttgataa ccttcgtttt ccatacaaag ctggcatttt ggataagagg
    30061 atgccttagc cttcttagcg gctgcaatgg ccttagggtc cttttcaggc tttgataggt
    30121 taatggtaat agccatatca ccatattgag aaggcactgt aaaggagatg tttttggcaa
    30181 ttgctgctgt tttgatgtag tcatttagct gactaagctg gtaaaaatct gagatagcct
    30241 gttgaggaga ttgtgcatag gtatcccaga agcgacgatt aaccacactt ggaatagggg
    30301 ttatcatgtt cattaattca gctcctaagc agtccttttc ttcaggaagc ctgcctattt
    30361 tgccattttc agcagctagc tcaaccaatg cttctttgag agctattaag gctgttaagg
    30421 aggtttcttg ccagacatgg ttctcaccaa ccaatgctaa aacccgattg cggatataaa
    30481 tagcgtcctc tgatgtgtag tcgctgtgtt caatcacctt ccttacaaag gtgtctatta
    30541 agcttgccat atcttatttc cttgaaagta gtcgtgctcc ctgagcaatc tcagccagat
    30601 aaaaggctgg agcatagcca atgaccttag tataggcctt gccaactgtt tcgataaagc
    30661 tatctacctt atccttagcc acgatagcaa tgccacagcc tccaaagcct gctcctgtca
    30721 tgcgagcccc taggacccct tcttgctccc aagcggtgtg gaccagtgtg tccagctcag
    30781 ggcctgtgac ctcataatca tgctccaagg atacatgaga agcattcatc agacgaccaa
    30841 attgctccaa tgctcctgct tcaagggcct gtcttgcttg gagtgttcgt tgattttcca
    30901 aaacagcgtg gcgagcgcgt ttgagacgtt taccatcttt gataaggtag ctgtactcat
    30961 caaagcgctg agcgtctaat tcccccagtg ctttaatatc cagaagggca tttaattcct
    31021 caagggcttg ttcacactct gctcggcgtt cattatactt tgaatcggct agctctcggc
    31081 gcttgttggt attcatgatg acaatcacgt gatcaccaag gtcaagcgga acagcctcat
    31141 aggctaaggt gttggtatca aggtatagag cctgcttatc agctcccatg cctatggcaa
    31201 attggtccat gatacctgaa ttcaccccga taaagtgatt ttcagcttgc tgaccgattt
    31261 taatcagatc taaccgttcc acatcaagcc caaacagctc ttgtgccaca atacctgtca
    31321 aaagctccag tgatgccgag gaggacagac cagacccatt tggaatgttg ccaaaaacgt
    31381 aaagctcaaa gcccgtatca ataaggtgcc cagctttttg caaaaaggag agaactccct
    31441 tagggtaatt agcccaaagg tcagcctgat caaaggtcag ctgatttaag tcaacctcaa
    31501 taatcccagc ctcttcaaaa tttgctgaga aaaagcgcag ctgctgatcc tcacgcttgc
    31561 gggccagccc ataggttccc agactgatag cagctggaaa gacatgtcca ccattgtaat
    31621 cagtgtgctc accaatgagg ttgatgcgac ccggtgagaa aaagacagca tctggctcct
    31681 tgccaaaaac gtcagtaaag ctttgcttaa gttgcgcgat atccattagc ggctccttta
    31741 acgatgttga tagcttgatt ttacgcttcg ctaagctgct cgtcaacatt tttactaaaa
    31801 ttttactaaa tattgctttt gaaaatgctt gtgatatact agaagaaatc agaaagaagg
    31861 tttgatatgg taacgcttaa ggatattgca gctctggcaa aggtttctcc tgcaactgtt
    31921 tctagagttt taaataagga ccaaagcttg tctgttggtc aagagacaaa gcaccgcatt
    31981 ctcacaattg ctgatgagct gggctaccaa aagcatttaa aagcgacgaa tagccctaaa
    32041 tcaaagctaa aaatagctat tgttcaatgg tattctcaag aagaggagct caatgacctc
    32101 tactattatg cgatccgcat tggcattgaa aaaagagctt atgaattgga ttatgatatt
    32161 gttcgttatt tcaacaatga cattttgagg gtttcagatg accatgccgg gattattgct
    32221 attggaaagt ttagcgcttg tcaaatcaag gagcttgaag ccttatccca gcatttggtg
    32281 tttgttgata gtgacacgct tgaattgggc cacccctgtg tcacaactga ctttgacaat
    32341 gcagtgctga aagttcttga ttattttatg agcaaaggga tttatagcat tggcatgatt
    32401 gctggtgagg aaaagacaac tgacggtaga gaagctttag tggaccagcg ctttcgcacc
    32461 tataaaaatt atgcctctga gcatgggatt tatcagccga ggtatgtcta tatcggtcct
    32521 ttttcagcac aatctggcta tgagcttatg acacaggcaa ttgaggagct aggtgatgat
    32581 ttgcctaaag cattttttat tgctaatgat acccttgcaa taggtgctct aagagctctc
    32641 caagaaagag ggcttgcggt gcctgagcgt gttgagctta tctcctttaa cgatactcct
    32701 ttaacaagac aggtctttcc tgcgctttct agtgtgactg tatttacaga ggatatggga
    32761 cgtatggctg ttgatgtgct taataggaat atccttaacc cagaacgtgt caagaccatg
    32821 acgatattgg cgacagagtt gaccttaaga gacagcacga ttggttaggc attgagctag
    32881 ctgggtaaag agttcagtaa aatgaaacac tagacggcaa ccatattaga agctttaaga
    32941 ctgactaatg acatagtgag tattatttga cgatgttttg aataatgatt ataatagtcg
    33001 tgaaatataa tagaaaatgt aggatatcat aaatgaaaaa agccctattg attgttaacc
    33061 ctagctcagg tggtgagaaa gccaaggaat atgaagcctt agcctatgat aaactagctt
    33121 cgtattttga tgatgttgac gttaagcaca ctgaaaaagg aggagatgcc aaacggtttg
    33181 ctcatgaggc agcccagcag cggctggaca gtgtctttgt catgggaggt gatggaacag
    33241 tcaatgaagg gatcagcggg cttgcagagc aggactatcg ccctaagttt ggcttttttc
    33301 ctctaggaac agtcaatgat ttggcacgtg ccttgggcat gtcgttagac ccagaggaag
    33361 cgattaatca gataagcttt gagacaacca gtcctctgga tattggtaag gtcaacgatg
    33421 cttactttat gaatgttgtt gccataggga cgctcccaga ggcgatcaat gatgttgccc
    33481 ctgaggagaa gacgaccttt gggaaaatgg cttattttat gtcaggcttt aagcagctga
    33541 tcaaaaataa aagctatacc ttccagctag atattgatgg caaaacaaaa gaaatcaaca
    33601 gcacaacact cttgattggc ttgaccaatt caatcggggg ctttgagcgg attttgccag
    33661 aggcacgtgt ggacgatggt ttgctgcacc ttatctatct gaaggatagc aatctattag
    33721 aaacggtgaa ggcccttcct agcctattga agggagttga ggcttcagat caaacacttg
    33781 gctatcaaac cttcaaggag gccactattg ccatgaagga aggacagcta tctatcaatg
    33841 tggacggtga tgagggtgag gccttaccaa tcactgtcaa ggtacttcct cagcacctgc
    33901 aggtatatcg ttaatctgaa taatgaagtt agtcattctt atacggtgga ggatatgacc
    33961 tagtgtgatt agcaatggta gccttaacaa gcgtgtccgt cgtagctgtt aatcagacct
    34021 tcatatcagc gtggctatac catttgcctt tagcatgata cgttaacagc agcaggctta
    34081 gtagagagag gatttggttt gaatcctctt ttttgctgcc tggggcttgg ctgatttggc
    34141 tgttcagtca tcatcaaaat gctttgcttg ctgtggtatg agcattgttg ttgacttggc
    34201 gggggttatt tgataggata gcagcacaaa aatcttaact agttaagttt tattaaaaag
    34261 catagacaat cacatcatca ctgcggcgac agccttgaga gtagctaaaa tggctactaa
    34321 ctattatctt agatcggctg ttgcctctag atgtctgttc atctgatgct ttttgttgtg
    34381 gcatgtagcc ccttaggtgg actttgaaaa cttagcttta aagcttaggc atcataggct
    34441 aagagagatt gctgctgttc ctatcacctc agaaagggta tcaaggggat atttcccatt
    34501 aaaactaggc tagttaatca aaataaagga gcttttttat gaagaaacag tcattgaaaa
    34561 aagtcagtct tttaacggtt actgttatat ctagcttggc cttggcagcc aatgccaata
    34621 cctatacgac ttatgccaga gacaacgttg tcactgcgac gtcgcaagcg gctgagggtt
    34681 ttgattttgt tgccacgata cttgatagca acggtcgtgc tcttgaagga aaaacagttg
    34741 tcttgttaga cacgacagct aatcccgcta agcaggtagc ttctgctgtc tctaacagca
    34801 atggtcaggc tatttttact caattaccct taaacattaa tttgagtgtt tctgttgacg
    34861 gggaaaccaa gggctataca gtgagaacca gtcttgctgg atctaaagag gcagcaagct
    34921 ttgtcgctaa gggagcaggg acaaaggagc ctctttatag taaaaatgtc attgatatta
    34981 cggtccgaaa tcaagatagt gagcccttag aagggcaaac agtcacccta aaaatacgtc
    35041 agggtcaact ggtgggaagt cttgtctcag ataaaaatgg aaaggtaacc ttcaaggatc
    35101 gtttgttgga cggaaccttt tatcattatg agcttaatgg taagtatata gggcaggtca
    35161 tgacaaaaat gtctgttaat gcttaccttg atacctcatc aagctcgtca tcaggtacgt
    35221 cacctcagtc caaggacact cctaagcagg aggatggaaa gtcaagtccg ctagaggaag
    35281 gctttcattt tgttgtcact gccctagata aagaggatag ggttgttgca ggcaaggagg
    35341 taagcttgac tgctctgata gacggtgcta agacgacaat tgcttcagca aagacaaatg
    35401 ctgatggtca agcagtcttt accaaactac cactatcacg taatatcagt gtctcaattg
    35461 atggtaagct acagggctat actgttcgca cgagtgagtc taatgagcat aaggctgctg
    35521 ctttttatgt cgacggtaaa ggaacaaagc ctgttgttta ctctaagaca ccagccatag
    35581 taactgttta tgatgccaat ggaaataagt tggcagggca agaggttgtg ctgaaaaatc
    35641 gatacggagc tatcagggca ataggcaaaa ctgatcaatc aggtaaggca acctttgtga
    35701 atcagctcat ggacggtatg ttttatgaga ttgttatcaa cggggtcaag atacctaaaa
    35761 aagcctctac cggtagtgat gtcagcggct ttttaaccaa agctcaaatc agaaccgata
    35821 ataaactcag cgagtctgag cgccattcta aagacacaaa gcccttaggc aaggagccaa
    35881 aggatcctga aaaggataag aatgtcgcta agccagaaac caagtcctcg tcaaaccgta
    35941 atgtagcccc taaagaaggt aaaaaagaga ctaaggcttt gccaagatct ggtgaatcag
    36001 cagcgccgat ggtagcgttc atgggagttc tattaatagg ccttgcagct gtcatcggtc
    36061 ttgtgacaaa acgtcgctct agctaaaacc aaataagtaa aaacgtcttg cagctatcaa
    36121 ggcgtttttt tgacggttaa gtgattgttc agcgccgttc tacaatctaa aaaaagaagg
    36181 ctaaatcttt tttaaacgta tcatgcaaca gtaagataac agacagtgag gtcatgcgtc
    36241 acagaccaca gtttatcata gagctatggc ttcttataaa ggttaagcag gttaggggct
    36301 gattaagcca tcgttttaat ggcttttatt ttttattaaa aaatttgaca aatacatcta
    36361 aagctgttaa aattaaccgg ttcataactg gttaatgagc aaaggagatt atatgaaaag
    36421 aaaatggata catttaacac tgttgcttgc tcttttttca ggtcttgttg cctgtagcaa
    36481 gcccaaggag caaagcaagc agtcaagagg catgacgatc gtcactagct tttatcctat
    36541 ttacgccatg acaaaggcgg tatctggtga gctaaacgat gttcggatga ttcagtcagg
    36601 ggcaggtatt cattcctttg agccatctgt aaatgacgtt gctgccattt acgatgctga
    36661 tttatttgtt tatcactctc acaccctaga ggcctgggct gatgatttgg atcctaattt
    36721 gaagaaatca aaggttgctg tttttgaagc ttccaaatct ttaaccttag atcgtgttac
    36781 tggtttggag gatattgagg tgacagatgg cattgaccct gctaccctgt atgatcctca
    36841 tacctggaca gatcctattt tagcaggtga agaagcactc gctattgcta aggagctcag
    36901 tcgtttagat cctaagcatg aggccattta cactgagaat gctcaagcat tccaaaagga
    36961 agcaaaagag ctggctgatg agtacactaa aaagtttaaa aagacatcat ctaaaacctt
    37021 tgtcacacag cacacagcct tttcttatct agcaaaacgc tttggcttaa agcagttagg
    37081 tatttctggt atttcgccag agcaagagcc tactcctcgc caactaactg aaattcaaga
    37141 ctttgttaaa gaatataagg taaaaacgat ttttgcagag gataatgtta atcctaaaat
    37201 tgctaaggcg atagctaaaa cagcaggagc aaaggtcaag ctgctcagtc cactagaggc
    37261 agcgcccaaa aacaacaagt cctatctaga caatttgaga gctaatttgg aagctcttta
    37321 ccaaagctta aaataaaggg agatgaaaac gtgaaaaaga agcatattgt tttaggatca
    37381 gctgtggcca ttttattggc tactaatgct gcttcatatc agtttggaat gcataaggct
    37441 ctaaattcct catctaaaga taatagcatt gcctatattg attcaaagga tggcaaaaaa
    37501 gccctcccca aagaaaaaac aatggatcaa atcagcgcag aagaggggat ctctgcagag
    37561 caaatcgttg ttaaaatcac agatcaaggc tatgtaacct cacatggtga tcatttccat
    37621 ttctacaatg gtaaggttcc ctatgatgct attcttagtg aagagctatt aatgacggac
    37681 cccaattatc agtttaaaca gtctgatgtt gttaacgaga ttctagatgg ctatattatc
    37741 aaggttgatg gcaagtatta tgtttatcta aagccaggaa gcaagcgtaa aaatattcgt
    37801 accaagcagc aaattgctga gcaggttgaa aagggaacaa aggaagctaa ggaaaaaggc
    37861 ttggctaagg ttgcccactt gagtaaggca gaggtggcag ctgttaacga agcaagaagt
    37921 caaggacgct atacaactga tgatggctat atctttagcc cgacagatgt tattggagac
    37981 atgggagatg cctttttagt gccccatggc agtcacttcc actatattcc taaaaaggac
    38041 ttatccccaa gtgagctagt agcagcgcag gcctattgga ataacaagca aggcggaaaa
    38101 ccaagtgtta ttggcggtca gcctttacca ggtcaaggag atcagcctag accatatgat
    38161 attcctgtta acccgattca ccacccagct gggaatttgc cgtcagtagg agatccaagc
    38221 ctatcatttg cagataaaac ctttggagaa ttgttggatc aattgcatgg cttggataag
    38281 aaatacaggc acgtcgagga agatggtctc atttttgagc caactcaggt gacccttgcc
    38341 aatgcctttg gctatgttat tcctcatgga gatcactacc atattattcc tcgtgagcaa
    38401 ttgtcagccc ttgaaataac cttggctgat cgttacctag caggtcaaac gcagggcagt
    38461 ccaatagcta agccaaagcc agctactcaa gaccagactg caaaagaggt tacacatcaa
    38521 ttccttggcc atcagattaa ggcttatggt aaaggcttag atggcaagcc ttatgacacg
    38581 agtgatcatt atgtctttag taaggcatct atttcctctg ttgataaggc aggcatcaca
    38641 gctaagcatg aggagcattt ccattacatg ggctttggtg agctagagca agaggagctt
    38701 gaccaggttg cacaatggct gcaggagcat ggtcaagcag atgagattgc aagggcatta
    38761 gttcaatcag acggtaaaga catgtccttt gacgctaagc atgtcagtcg caaggtaacc
    38821 aatggcggta aggttggtta catgatgaca aaagatggca aagagtattt ctatgatcgt
    38881 gagcatttag acctaacaca aattgccttt gcagagcaag agctcatgct taaggataag
    38941 caacactata tttatgacat tgttgataca ggcgttcagc caaagctagc tgtagaggta
    39001 tccagcctac cgatgcatgc tggtaatgca acctatgata catggacatc ttttgtcatt
    39061 cctcacatcg atcatatcca tgttgtacct tattcatggc taactaagga tcagattgcg
    39121 accatcaaat atgtcatgca gcaccctaat actcgtcctg atgtttggtc taacccaaat
    39181 catgatgaag ctggaggagt cattgctaat gtcacaccag ctgatcaacg tacttcaatg
    39241 gaaaactggc aaattattca ctctgccgaa gaggtccaag cagctatcaa ggcaggtcgg
    39301 tacgcagctc cagatggcta tatttttgat cctaaggacg ttcttgctga aggaaccttt
    39361 gtttggcgta atgattcctt tagcattcct agagttggtg gacgctcttt aagaaccatt
    39421 actaaagatg agttatctca tgatgaatgg caaaaggttc aagaattatt aggcaataag
    39481 acctcagacg cagctgaaag cactattaag ccaaccaaag accaggaacc gtcagcgcaa
    39541 gatactgccg cagatggcat agagcagacc aagtctttat ttgacgatat tcctaattat
    39601 ggtttagatc gggcaactct tgaacgtcag atcaatcagt tagctgaaat agcaggcatt
    39661 aaaccggagt atcttatttt cgtgccagag ggtgtcaaat tctatgacca aaaaggacac
    39721 ctaatgcttt atgatgtgac aacattgcaa caaatcaaat aaacactata aaatagctaa
    39781 ggcatacaaa tcacagctta tccccaaaaa gctattggta tgatgacctg ttcttacgcc
    39841 tcacagccta agatcgctta gtaggctttt gcttgcagca acagtcagag aagctgactt
    39901 gatcagcagc ttagcacctc atagctttta aagcattgga tctctgtagg ctatatgtgg
    39961 gttttggttc caagaaagtc tatatgacct aaggagggca gcacagaaag agtttttacc
    40021 aattaacctc acacctaata gtcctccagt caaaaccgcc tagcctttaa tagctagacc
    40081 tcccctttaa agtggacagt gaaaaacaat cactaaaaac gataagggga gttttttggt
    40141 gtctaaaagg gttaggaaaa aggttagcag ccgtacaatt
//
LOCUS       DARYJX010000018        39693 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYJX010000018 DARYJX010000000
VERSION     DARYJX010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39693
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..274)
                     /locus_tag="TU257_000932"
     CDS             complement(<1..274)
                     /locus_tag="TU257_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL0833953.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGL"
     gene            complement(311..1687)
                     /locus_tag="TU257_000933"
     CDS             complement(311..1687)
                     /locus_tag="TU257_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0833954.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(1855..1986)
                     /locus_tag="TU257_000934"
     CDS             complement(1855..1986)
                     /locus_tag="TU257_000934"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833955.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(3095..5041)
                     /gene="thrS"
                     /locus_tag="TU257_000935"
     CDS             complement(3095..5041)
                     /gene="thrS"
                     /locus_tag="TU257_000935"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL0833956.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(5632..6966)
                     /locus_tag="TU257_000936"
     CDS             complement(5632..6966)
                     /locus_tag="TU257_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0833957.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(6968..7966)
                     /locus_tag="TU257_000937"
     CDS             complement(6968..7966)
                     /locus_tag="TU257_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0833958.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(8262..9737)
                     /locus_tag="TU257_000938"
     CDS             complement(8262..9737)
                     /locus_tag="TU257_000938"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0833959.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(9807..10808)
                     /gene="ccpA"
                     /locus_tag="TU257_000939"
     CDS             complement(9807..10808)
                     /gene="ccpA"
                     /locus_tag="TU257_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL0833960.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            10982..12067
                     /locus_tag="TU257_000940"
     CDS             10982..12067
                     /locus_tag="TU257_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0833961.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSILPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(12241..13824)
                     /locus_tag="TU257_000941"
     CDS             complement(12241..13824)
                     /locus_tag="TU257_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0833962.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            14062..14913
                     /locus_tag="TU257_000942"
     CDS             14062..14913
                     /locus_tag="TU257_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0833963.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            15174..15842
                     /locus_tag="TU257_000943"
     CDS             15174..15842
                     /locus_tag="TU257_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0833964.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            15957..16883
                     /locus_tag="TU257_000944"
     CDS             15957..16883
                     /locus_tag="TU257_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0833965.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(16867..17055)
                     /locus_tag="TU257_000945"
     CDS             complement(16867..17055)
                     /locus_tag="TU257_000945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833966.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(17167..17634)
                     /gene="smpB"
                     /locus_tag="TU257_000946"
     CDS             complement(17167..17634)
                     /gene="smpB"
                     /locus_tag="TU257_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL0833967.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(17637..19961)
                     /gene="rnr"
                     /locus_tag="TU257_000947"
     CDS             complement(17637..19961)
                     /gene="rnr"
                     /locus_tag="TU257_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL0833968.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(20048..20284)
                     /gene="secG"
                     /locus_tag="TU257_000948"
     CDS             complement(20048..20284)
                     /gene="secG"
                     /locus_tag="TU257_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL0833969.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(20330..20476)
                     /gene="rpmG"
                     /locus_tag="TU257_000949"
     CDS             complement(20330..20476)
                     /gene="rpmG"
                     /locus_tag="TU257_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0833970.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            20964..22796
                     /locus_tag="TU257_000950"
     CDS             20964..22796
                     /locus_tag="TU257_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0833971.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPRG
                     ENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPS
                     TITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            23110..24150
                     /locus_tag="TU257_000951"
                     /pseudo
     CDS             23110..24150
                     /locus_tag="TU257_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(24313..24906)
                     /locus_tag="TU257_000952"
     CDS             complement(24313..24906)
                     /locus_tag="TU257_000952"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL0833972.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(24903..25724)
                     /gene="mutM"
                     /locus_tag="TU257_000953"
     CDS             complement(24903..25724)
                     /gene="mutM"
                     /locus_tag="TU257_000953"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL0833973.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(26139..27938)
                     /locus_tag="TU257_000954"
     CDS             complement(26139..27938)
                     /locus_tag="TU257_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0833974.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(28099..32739)
                     /locus_tag="TU257_000955"
     CDS             complement(28099..32739)
                     /locus_tag="TU257_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL0833975.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(32912..34259)
                     /locus_tag="TU257_000956"
                     /pseudo
     CDS             complement(32912..34259)
                     /locus_tag="TU257_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(34324..35640)
                     /locus_tag="TU257_000957"
     CDS             complement(34324..35640)
                     /locus_tag="TU257_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0833976.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(35633..35965)
                     /locus_tag="TU257_000958"
     CDS             complement(35633..35965)
                     /locus_tag="TU257_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0833977.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(35975..36292)
                     /locus_tag="TU257_000959"
     CDS             complement(35975..36292)
                     /locus_tag="TU257_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0833978.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(36316..37215)
                     /locus_tag="TU257_000960"
     CDS             complement(36316..37215)
                     /locus_tag="TU257_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL0833979.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            37395..38597
                     /locus_tag="TU257_000961"
     CDS             37395..38597
                     /locus_tag="TU257_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL0833980.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(38760..39236)
                     /locus_tag="TU257_000962"
     CDS             complement(38760..39236)
                     /locus_tag="TU257_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0833981.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(39381..39590)
                     /locus_tag="TU257_000963"
     CDS             complement(39381..39590)
                     /locus_tag="TU257_000963"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833982.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        12040 a         9433 c         7309 g        10911 t
ORIGIN      
        1 ttaatccttt aataatatcg tcttcagtat ctttagcact aacaaagata ataggagaag
       61 caactttatc tcggattaat tgacaaattt gtgtaccttc aacattaggc atcatgacat
      121 ctaataaaat caagtcaaac ccttgaaaat ctctaaaatt gattggaaaa gtcacttctt
      181 gataggttgt taccttgtaa tttttcatct caagaatggt ccgcataagt tttaaaatct
      241 cataatcatc atcaacaact agaatcttat acatagtctt acctcataat agttacactg
      301 ttattttaca ctattttgag ataaaatctg taatatttaa caatctaatt ggttttccat
      361 tatcatccaa gctactccaa gagttactat acaaaatagt tatggcctca tctggtttat
      421 cttttaaatc atatttttcg atgattaaac ctaaggcagc agctacttta ggggctgcaa
      481 tagaggtccc gtagccataa gtatatttcc cttctagtgt tgggataata acccaatctt
      541 gctcaaataa tttattgtta atccaagtgt catagccatg aagcgctagc ttcttgcttc
      601 ctccacctgc cgcaaagata tcaacgacat tccttccacg attggaaaag ttagatattg
      661 caccatcacc atcaacagat cctactgtca caacattatc tagctgtgcg ggaatatcct
      721 ctattgtccc atcgactgaa ctaaacgctc ttcctgtgag agcactgact aagttcttaa
      781 gctcagcttg attatttaag ttagctccct catcaccaac agaagcaact accactgagc
      841 cttgtttgtg tgcataattg attgcccgtt gatagctatt gattagagca gttctatctt
      901 catcaatatt tgatgaagcc tttaataaat actgaccaag actcaaattt atgacatcaa
      961 catcatcctt tgctgcttga ataattgctt ttaaaatcca ttcatcttga gcgtttccct
     1021 cttcaaacac cttatacatt ctaaccttca tgcctggagc aattcctgta taataaccat
     1081 ttgaagacat ttgtccaaca acagatgtac catgacctgt tttatccaaa acattattaa
     1141 catcaattgc cttagttact ggatcctccg taaaattttg aacagaaatg atctttgaag
     1201 aaatgtcagt attattatca gtaataccag aatctattac accaatggtt acctcacctg
     1261 atgacttatg ccaaaaccta ctactagtac taatacttct ttgcatatcc cattgtttat
     1321 tccagtaatt taaatcacta tctaaataaa atgcatgccc aaactgatat gtcattttgg
     1381 gatttactgt aaaagtatta ttccttgaaa tgtcatcaat atagttacaa ttcttttcca
     1441 aaatcataga tgagtcattt gcagcagcga ttgtcaaaac attaatttca ggaatttcat
     1501 caagcactat cattccctga tcatttaatt gcttttttac cttattggta tctaagcttt
     1561 cttttataag aatattatat tgagttttgc tactagtctc agcatagaca tgtaacatat
     1621 gaaattgaga tacaaaaata gacagtagca aacagaaaat caacatttta tgcttcatgg
     1681 tcagcactcc tttaagtatt gtttttacac ttatcgtatg actaacattt cagatttgtt
     1741 tcagattcta gaaaataata cttactattg tgcttattta agtccaaaaa ttagcattac
     1801 actcattaag tatctgagat taatctagct aacattctaa attgttttct cccactaatc
     1861 ttttgttctt aattccgact tataattaaa gacaaaagct aatttttcta actgcctcgc
     1921 atagcactca tacttgccaa tcattgttgt catcgtctcc tgattgagct tagtttcttc
     1981 ttccacctgc tccagtttac tagctgatat gcaagtgcaa tggtcgtttt ttgtgaatca
     2041 cacctacttt gaatctggta aaatcattct actaacaaac ttcctgtgta atttctagta
     2101 gcctaggtag cctgataaag agatttcttc aaataaaaat aaccatgtcg aatgccagcg
     2161 ctccatttct taccagcatt ttcattattc cccagctaaa gctctatcca tgaggctaag
     2221 tgacctgtgc ttagaattaa ctcatatcca cactagtctc agaaataaag actgaagcta
     2281 tcatgatgtc actactagga atgaatgaaa tctagggttt ctacttgaca gtcatagtga
     2341 gacaaacaag cggcaatttg ctcttctaaa ctcccgattt gtttctaata gcaagcataa
     2401 atctccatag actaccccca tagaaaatgg tggtgattgg agaaatcacc attaagtgct
     2461 tcacgacgtt gaggagcttt cttcttcaaa ctagtataaa caattaatgg actacttact
     2521 ctagctgtca taggcgtttg agcaatcagt agttgaaata gcttgcaacc gaaagcaccc
     2581 agcatactct caatgcggat cggaagttca atgccaccta actgtagaat tttataatgc
     2641 aaattgtcct ttattaagaa ccttattgat cattttaagc tttagttcgg gagaggaacg
     2701 aatctttttc cttagcagct ttacaatcaa ttaatcgtgc taaatacttt aaatggaatt
     2761 gattgatatc aaattgtttg aatgaataac tctggttttg taggccgcag atttctacct
     2821 tgtcttgatg tcttaatgtc atgttaaaag caccccattc gttagatagt ttgtctaact
     2881 tttggggcgc agttcattca ttagattttt tatctaattt ttgagaagca gtttacttct
     2941 gatgagggct tctatattgc tttcattagt tctatgagtg agagcaaagc tcttgtagct
     3001 atttgtccca gattttttta tgtcatctgt tttgcaagtc aagctgacgt ctgcttaatc
     3061 agcctatcta aaaccagctt gcttggtctg ctttttagcc ttcagctggg cgtgatttgc
     3121 gggcaatatc agccaaaatg ttatcaacaa atgctgaaat agcttcggta tgtgttgcct
     3181 tactgccata gcggcgcaca ttaactgact tgtcctgcat ctccttatca ccaacgatta
     3241 attggtaagg gattttactg gtttgagagg cacgaatctt atattgcatt ttctcattac
     3301 gatcatccac atctgcacga atcccatgat cacgaaggat tttagcaacc tcccaagcat
     3361 agtcaatatg ggcctcattg gaaattggga taactgttac ctgacgtggt gccagccatg
     3421 ttgggaaagc tcccttatag gtttcaatca aaatagcagt aaagcgctcc atggttgaaa
     3481 tcaccccgcg gtggatcatc accggacggt gttcttctcc atcagcacca atatagctca
     3541 gattaaaacg ctcaggcagt aagaagtcca gctgaatggt tgatagggtt tcttcatttc
     3601 caagggctgt tttgacctga atatcaagct ttggcccgta aaaggcagcc tctccttctg
     3661 cttcaaagta atcagcgccc atttcatcaa gcgcagcctt cagcatgctt tgagcatttt
     3721 cccacatctc atcgttatcg taatatttat gtgtatcctt tggatcacga taggacagac
     3781 ggaagcggta atctgttagg ttaaaatcct cataaacgtc aataatcagc tgaagagctc
     3841 gctggaattc ctcctgaatc tgctctggcg tcacaaacag gtgcccatcg tttaaggtca
     3901 tctcccgcac gcgctgaagc cctgaaagag cccctgattt ttcatagcgg tgcatcatac
     3961 caagctctgc aatacgaatc ggcagctcgc gataggaatg cacatggttt ttataaacct
     4021 gaatatggtg tgggcaattc attggacgaa ggacaaattc ttcaccatct cccatatcca
     4081 ttgtcgggaa catatcctcc tgataatgct cccagtggcc tgatgtttta taaagctcaa
     4141 ctgaagcaag cggcggagta taaacatgct gatagcctga tgccagctct ttatcagtga
     4201 tatagcgctc aagcgtgcga cgaatcgtcg ctccatttgg tagccaaaat ggcaagcctt
     4261 gtcctacctc ctgagagatc ataaacaaat caagctcctt gcctagctta cggtgatcgc
     4321 gctccttagc ctcctcaagg cgtgtcaaat aggccttgag gtccttttta tcaaaccagg
     4381 ctgtcccata gacacgctgc atcatgttat tatcgctatt gccacgccag taagctccag
     4441 ctacatttaa caaatgaaag acccgaatcc gacctgttga cggcacatga ggaccacgac
     4501 aaaggtccac aaattcaccc tgacggtaaa cagttaagcc agccgcatca tctgcatgct
     4561 cattaatcaa ctcaacctta taagggtcat ccttaaaaag ctcaagagcc tcttcttttg
     4621 tgatctcctc acgaatacat ggaaagttct ctttgacaat ttttttcatt tcctcttcaa
     4681 tgcgaggcag gtcttcgtta gagatttgac catcagcatt atctgtatca taataaaaac
     4741 catctgcaat ggcagggcct acaccaagat gcagcttggg gaacaagcgc ttagcagctt
     4801 gagcaaacaa gtgagccgca gaatgacgca gcacctcaaa agcgtcctca tgatcagcag
     4861 ttataatttc tatactaccg tcctcttcaa tggcgcgcgt ggtatcaatt aattgaccat
     4921 taaacttacc agccaaggcc tttttagcta gagatttgct gatagagtca gcaatctcaa
     4981 aggttgtgac accagattca aattcacgca ccgcgccgtc tgggaaagtg attgtaatca
     5041 tctgttttct cctataaacc atctagatac ttaaaacaag ctaatcaagc agggctatat
     5101 ctcccaagcc ttctgctgct acgacaaaat aaaaactgac tgcctcccaa aggacgcaat
     5161 cagcgtggtt ccacctttat ttatgcatga caaagaaatc ctgtcctgca cctcagcttg
     5221 gctatatcgt gaccaccgtt ttatgtttgc ataaaagcaa ggaaggagta ttacactaga
     5281 caccctgtgc tcttctcacc aaccagcact cgcttaaagg atgcgaccta atctaacttg
     5341 tcttcctgat tattatagca atatttggaa ataattcaag tgatttttcc taaaaaagct
     5401 gagataagcc cacagacctc caagcccaca aggcaagaat gactaggcaa ggaaccctga
     5461 aacttctgcc acaagccttt gaagaacagc tcaaacagga cttgccgcct gtcgtctcag
     5521 ttcacaagac aacaaactaa atcctttaga caaatgatta tcctaaagag ctatctgctc
     5581 tctcacgcag aaccaaagcc tgtaattgca ggcttctttg tttatttagc cttagtccaa
     5641 aaagtctcgg atcgcattga ccagcttgat aggggctttg agcaccttga cagatgtcag
     5701 tgcagttgcc ttagctgctc gcttaggcaa gtgaatcgct ccttgaacca gcttgattga
     5761 gccactcttt tctgttcgat tgagatagag acttagcttt ttcgtctctt tattgtgtcg
     5821 cgaaatcaag gtatctaaat aaaaggtgta cactgatttg ccaaaatgct gagctgaaat
     5881 ctcatagcgc ttctcatcta gcagcctctg gttcatttga ggtgtttcta aaatggcatc
     5941 aataatcgca tctgacaatt ctgactcagc ataataaagt gttccaaaca tcttatcggt
     6001 aatcaaatca tctaggtagg gattgccatg agcgatgatg ggcttgccac tagcaaggct
     6061 ctcaatataa gttagcccct gtgtctcact cgttgacgct gaaataaaga aatcacaggc
     6121 cttataataa agcccaacct gatcatgagc aatcatacca gtaaagacca catgatcctc
     6181 aacgcctaag ctgacagcca gctcctttaa ggcttgaaga taaggaccat caccaacaat
     6241 gacaagcttg atcctgctat tttcactcaa aacagctggc agctgatgga taatagcctg
     6301 aatattcttc tcataagaca cccgcgacag gctcaatagc atggtctcat catcagaaat
     6361 ggccaattcc tttctcaagg cagcgacatc ttctttttta atatcctcac gaacatagtt
     6421 ctctagtgca atgccagtcg gaatcacacg cttaggaatg gttacctcgt acccttccaa
     6481 aagatttagc acaatccgac ttgggcaaat aacaccatca aggtccttta aatacccacg
     6541 aagcaggggc ttgaccatgc taggtcgaat gatcttacca ttagcaatat agctcacata
     6601 atcctcatac tgggtatgat aggtgtgaac aaccggaatt cttaaggcct tgcccaccat
     6661 tttgcccaac aaacctaagc taaactctgt ttgagtatgg ataatgtcta aatgatattc
     6721 cttagcaatc ttgtaggagg aaatgagccc acgataaacc acacgacgat ccgtaaagga
     6781 cacaaaagga acacttggta accgaataat ggtcggatcc tcaaagcgct taacatgctt
     6841 gtctgttgtt gtgaaaatat agacctcatg cccctctttt tccagctcct cctttagggt
     6901 gcgaatactg gtagccactc cggaaacctg tggaaaatag gtatctgtaa atagacctac
     6961 acgcatctta taactccatt actttttgat aaatagccac taattgatga gcaatcctat
     7021 caaggctgcg cccctcggcg acacgatagc cggcctctgt tttgttgctt tcccctgaaa
     7081 gaatgcgtct taaggctgca acaaagcctg aggtatcatt tgccaactca gcactgtctt
     7141 gatcaatcca gccctcatag actggtatat cgcgtaaaac aagatgctgc cggctggcta
     7201 aggcttcgag aaccacaatg ccttctgttt cctcacgact tgggaagaaa aaggcgtcag
     7261 ccccagtcat agccccctca tacacatctc ccttgatata accagggaag atcacattat
     7321 cggggtgctt accgttgaca atctggcgga cacgagcagg aataacccat ttattggtat
     7381 caccaaacca gataaaccga acatctggca tcatctcagc aaccttaaca aactcatcaa
     7441 tcccttttct aagaaagaaa agccccgctc ccatgactac cttctcaccc tctttgaggt
     7501 taaaataacg ccgaaaggca gcttctttgt cagcattagc accatattgc tccaaatcaa
     7561 tcccattaga tactgcaaaa ataggagtct taaccccgta atgctcaatc aaggctttag
     7621 aataaggggt cggtgtgata atggcgtccg ccttattgta aaagcggcag agataggctt
     7681 tgaataaagg agacactaga tttgaaaaaa taaaggaatt tctaaaatcc tcctctgtcg
     7741 aatgcccatg catgatcacc tttttaccgg ccttttgagc ctttgacatc aaaagccagc
     7801 ttttaagccc ataggtattg agatgaacca aatcatagtc gtcctttgga tcagtggtga
     7861 actcctgtcc cacaagcgat agcgcttttg cctgatgctt aatcgctcgc ccgatacctg
     7921 attttcttaa ataattttct gcttctaaat acaataagac tttcatactg tctattatag
     7981 cctattttat ggtatttttc actaagagag ttaaaaatca gcccttagac tgattttagg
     8041 gtaaggcttc ttctacccct atactcatct caaaaatgct tttaagtcct gcttttgctg
     8101 tcatcaaatg gctgatcttg gtaatatcag ctagaccaag atcgtgaaag ctccagctca
     8161 aggctcacgt attagccctt tcaagaaagc ctcccacctt tctcactggc caaaaagcca
     8221 gcaagacctg gccttttctt ctgattaatt cagcctatca gctaagcttc ttcttttggc
     8281 tgtgcttttt gtaacaccca ggctgagata gagcctgcct ctaccttgaa atctgcccag
     8341 ccatcctcag caacaacaac agtctcctga caattgtcta agaaatcaca aaaaacttga
     8401 ccagcatagg cttgaccaac ctccatgtgc ttccagcctg catcgccatt agacaaaaca
     8461 actgccaaag gctgaggacg ctgatcatct cctaagcagg tccagccgat acaattggca
     8521 tgatcaaagt aatcaatctg ctccccatag accagctgct gcctgagctc tgccattttt
     8581 gtgataacct ccttaaaact ttgctgaggg tagtctccag aaataccata ataatcacca
     8641 taaaaaagac agggcttgcc ctcttgtcgt aaaagaatca ggccataggc taagggcttg
     8701 aaccattcct caacagttga ctctaaggct tgccctcttt gggtgtcatg gttttccaca
     8761 aaggtaatag caaggtctgg ccgactagcc acaagactgc catcaaaaat agtggtcaaa
     8821 tcaaaatcag ctccctgctg gctagcatta aaaaaggaca tgtgcagcgc aacatcaact
     8881 agagcaaact gagccttcgt tgcttcgagg taatcctcca tagattcctg atcagacttc
     8941 cagtattctc caaaaacctc taaatcgggc tttagctggg tacgaatatc attgataaag
     9001 gtctgaataa aataagaatc aatatgcttc acagcgtcta aacgaaagcc ctcaatacca
     9061 gttgtctcaa taaaccactt ggcccaatcc tgtaaatttt ggattacctc aggatgcttg
     9121 aaatctaagt cattgtacat tagataatca aaattaccat gctcatcgtc aatcagctca
     9181 tcattggccc agcccttgtt atcaccggtg atcatgtaaa tacctgtttc attagccttg
     9241 gcgtcataat ccaatcccgt aaaatggtac cagtgccatt taaagtcatt ataggtattt
     9301 tgtctgccgg gaaaatcaaa gcctgtccag ccttcaatct catagggctc tgtaagggcc
     9361 tgctgacggt tctctggatt cattttgatc acagaaaagc gttccttgtg atcaccatta
     9421 gccttgtggt tcagcacaac atcagcaata ggctttattt ttgcctcttt tagggctgca
     9481 atcagctgca aataatcctc tttgctgcca tattttgtgc tgacagttcc attttggtta
     9541 aactctccca aatcaaacaa atcgtaaaca ccgtacccca catcatcaga gctagtgccc
     9601 ttaaaggcag gcggcagcca cagctgacta acccctagct gttgtagctc aggaatactg
     9661 cttttcagcc tttgccaatg ccttccatcg gcaggcaaat accattcaaa ggcctgcatt
     9721 aatagttgat gactcatctt aacctcctaa aaaggacaaa ccagaaaact cctagtttgt
     9781 cctcaaaact gcctaaacag gcagaactat tttgttgtcc cacgcttttt aatgccatgg
     9841 ttcaataaaa tttctttttc ttctaattct tccttattca tgatcttagt gagcatacgc
     9901 atgctaacag cccccaagtc atagaccggc tggctgatag agctcaaatt tggacgtgtg
     9961 tactgaacga ctggagaatc attgcttgtg ataatctcaa agtcttctgg aacacgctta
    10021 ccagcttcaa aaagaccatt caaaaggcct gctgccagct cgtcctctgc aacataggca
    10081 gctgtcgctc cggaattgat cacacgctga gccagctcaa agccttcctt ataagaatag
    10141 ttggcctcaa acaccagacc ctctttaaag tcaagcttgt tcttcttgag tccgtccttg
    10201 tagccagcta aacgcacctt tccgttgata tcatcaatga gcggccctga aacaaaggca
    10261 atgctttggt ggtctttagc taaaatatcc accacatcag caacagccgc cttataatca
    10321 atgttaacac ttggcagctg atgatccaga tcaaccgttc ctgccagaac gattggcgta
    10381 cgcgaacgag aaaactctgc ccgaatcttg tcagtcaagt gatgtcccat gaaaataatg
    10441 ccatcgacct gctttgcaaa gagggtattc acaacattga cctctttatc atcgtcctca
    10501 tcacttgaag caagaacaat attgtacttg tacatagcag caatatcatc aattcccttt
    10561 gccagaatag aaaaatagct atttgcaata ttaggaatca caacaccgac tgttgttgtc
    10621 tttttacttg caagaccacg agcaacagca tttggacgat aatcgagacg atcaataacc
    10681 tctaagacct ttttgcgggt attttccttt acatttttgt taccatttac aactcgacta
    10741 actgtcgcca ttgaaactcc cgcttcgcga gcaacatcat aaatcgtgat tgtatcatct
    10801 gtattcattc ttcatcttcc tttctaactg aaaatgacgc tttcaaaaag tattttagca
    10861 tgatttgtaa ccactttcaa gtattaacgg ttgatttttg aaaaagtttt caaaaattca
    10921 taataagctt gcttttttaa gtattttttg gaaaaataga aggcagaaag aaggtttatc
    10981 tatgactaaa ttagatcaaa ttcgtttgta ccttaatcag gaaaaggctg agcttgctat
    11041 cttttctgat tctgtaacga tcaattactt aactggtttt ttatgtgatc ctcatgaaag
    11101 gcagatgttc ctatttgtct atcatgacaa ggctcctgtt ttgtttgtac cagctttaga
    11161 ggttgcaagg gctgaacaat tgctggactt ccctgttttt ggctacgttg actctgaaaa
    11221 tccttgggaa aaaatcaagt ctatcctacc aagcacagca gcaaagacca tttacgctga
    11281 gtttgatcat ttgaacatta ccaagtttca agggctgcag agtgtctttt caggacgctt
    11341 tgacaatcta accccttaca ttcaaagaat gcggctcatc aagtctgctg acgaaattca
    11401 aaaaatgctg attgctggag aatttgccga taaggctgtc aatgtgggct ttgataatat
    11461 ttcacttgac gtcaccgaga cagatatcat cgctcaaatc gaatttgaaa tgaaaaaaca
    11521 aggcatcagc aagatgagct ttgaaacgat ggttttaact ggtaacaacg ctgcaaaccc
    11581 acatggcatt ccaggaacca ataaaatcga aaacaatgcc ctgctgctct ttgaccttgg
    11641 tgttgaaaca ttaggctata ctagcgacat gacgcgtaca gttgccgttg gaaagccaga
    11701 ccaatttaag cttgatattt atcagctttg cttagaggct cagctaactg ctcttgatat
    11761 gattaagcca ggagtgactg cagctcaggt agatgccgct gctcgccaag tgattgaaaa
    11821 ggctggctat ggcgactact tcaatcacag gctcggccat ggtatcggta tggacgttca
    11881 cgaatttcca tcaatcatgg ctggcaatga cctgattctt gaagaaggca tgtgcttctc
    11941 agttgagcct ggtatctata tcccaggcaa ggttggggtt cgtattgagg actgtggtca
    12001 cgtaactaaa gacggctttg agctcttcac ccaaacacca aaagaattac tatactttga
    12061 agggtaatag gaggcttaaa aagcctgaaa caaaatgtct cagaccctaa tatctaaagc
    12121 aacagcactt ggtctgttac ttttcatatt acaggctatt ttctcacaag gaaaagtcaa
    12181 agcacccctt gatgggaaat cagaggggca aaagctattt gtactaagct caaaagctaa
    12241 tcaagagcac ctgaccagct ctttatcctt taagtgataa atgcaatcat aagactgtgc
    12301 attatattta tgagctatct caaccatggt gcaggggagt gaatggagta actcacgaat
    12361 ctctctggcg ctttctttgt ctagggcagc tgtgacctca tcagccagca aaatcggttt
    12421 tagtatcagc aagcagcgtg caatttccag cttcatgatt tgcccgccag agagattttg
    12481 cccatctaga tggagatcaa gatctccgtt tagctcattc caaagatgaa cctgctgtaa
    12541 tatctccttt agtcgctggt ccgaataatc ctgaaacagc gtgagattat ctcgcaagct
    12601 tccttcaaat atgtaaggct tttgatgtat caaagacaca acatcatagg aaggaaaata
    12661 gcgttttcca ttggcagctt caaaataaat agttccagaa taatccttat cctcaccaca
    12721 caaaagagca aataaagtag atttcccact accactggct cctgttagca aggttttgtg
    12781 ccctgctgaa atatgaccat ctatcccttg aaaaataagc ctatgatcaa aatacttatc
    12841 taacctctta aagtagatat caagtgtaag atcatctgta ggggttaagg cttgatgttt
    12901 tgtctcttcc tccagagcca atactctaac catcttctcc ttaacagcag ttgcagactg
    12961 taaactcgaa gtagcttcta ataattgctg caagggagag acaagattcg tagaagctgt
    13021 tatcatagca atgagagttg ttagtgatag acttgaatag ctcatcacca acagaccaat
    13081 aataagagga ctaaccaagc caatcccttt taatggacca gtccaaaaca ttaccagatt
    13141 gtgggtagta taatagctat attgcttgtc ttccatatgc tgaatcattt ctaacacatg
    13201 gtgagcaaaa gcttcgttgg cttgattact ctgtatcgtg tctgccccct tagtaaaatc
    13261 ggtgatactg gctaggcttt tctccctcgc ctgactaagc tctaagcctc gtgattgaag
    13321 taagtgattg aacacaaact gtggaataat catcaaaaag ccaccaatag taaaggcaat
    13381 accaatataa atatcctgca aaagaaggta caagacagag gctaagatag ataggccaaa
    13441 aacaggataa atgaataagg ggaccaaata ctcctgccaa aacataggaa tatcttgggt
    13501 caaaaacgaa tttaaggctg aagtaaaata gttgagctgt ttatgataaa aatgatataa
    13561 agccttcttt gcaataaggc aattaaacgc tctaaccata gaacgtgcta aaatgttatt
    13621 aagatacatg cacatataaa taaagacaaa aaaagctacg cctccaagac caaaaagcaa
    13681 taccattcct ttattgttca tatcaatttg ccctgctatc tgaattaata ctgataacaa
    13741 tagtccctgc aaggaataga gcaaagccaa taaactatac aagcaaagct gccattttga
    13801 aatgacttgt aaaatacttt tcatatcaat cactcctcac ctgaaaccta aatgtatcgc
    13861 tctcttggaa agtataaacg aaacatcctc atacaccaat catttccacc acaaactaga
    13921 ttcttgaatg ttaaatcaag ctcttgatca aaatcatgtt ctctgatttc ttgaacaacc
    13981 attggttctc tcctttcatt cttactattt ctagtatata atgggaaaaa atacgaaagg
    14041 aaaaatttcg gaaatccgga tatgaatatc agagagaaat ttaaagcaat tcgtaaacaa
    14101 agaagactat ccttaaaaac gcttggtaaa atagctggct cagccactag tatttctgac
    14161 ttcgaaaatg gaaaaacgaa cctttctaat gatgttttat tgcagctttt aggctttatg
    14221 attgttgaaa taaacgagct attcgaatgg gaggattttc acgaaaagga attggttgaa
    14281 gccatcaagc aaatcgaact ggcaataaaa tctaaacata ttcctgctct atctcagcta
    14341 cagcaggact ttcaaagctt atctaagaca aaggaacagt acatttacca catcatctca
    14401 ctgatcctaa ccatcaccat tgcagaatat caaaacaaag agatcgatcc acacatcatg
    14461 tctgagctaa cagactactt ctttttcttg gagtattgga ctaaccttga tgtcggccta
    14521 ctaggaaaca tcgtccacta catgacaaca gatgccctaa tcttattgac aaatgacatc
    14581 ttagagcata cgcctcaagt actccgaaat aacctagatc gtattaggat cgatactgta
    14641 ttaaactgtc ttactgtctt gattaatcgt aaagaggaga aggcaagcag aacacttctt
    14701 aaattattat ttaacaaaca ttatcctaat tactttgcct ttgaaaagct ctatttacat
    14761 gaattacaag cagtctatga ttttaactgg aaagataaag aacaggcgct tgcagctcat
    14821 cacgtcatac tggctaccat ttcattacta tttacagctg atgaagccaa agaatgggac
    14881 agcttctttc aagaaagtac tagctctttg taatactcca gctcatacac taaagaaaag
    14941 caaggataat cacataaaaa ctaatcacat cactttgccc tgctagctga attagcttgg
    15001 gtcatctctt atgcccagca aaacatcatc tagtctcagc tttcttccaa agcttcttgt
    15061 ctctctgggc ttgcaagctt ttgatagctt aagaggcaca agcattaaca aaggctaaca
    15121 aatgcctgta aaaatatgct atgatagggg taacaaaaac ctaggaggtg cttatgtcac
    15181 acaaatccat tcatcaacag cttagaaatg ctttttcctt tcggacagcg gtacgcgtct
    15241 acaatgacca aaaaatagcc aaagaagact tagacctgat tttagatgct gcctggctca
    15301 gtccttcctc tatcggcctt gaggcctggc ggtttgtcgt tttagaaaac gaagctgtca
    15361 agcatgagct aaaggaggtc tcttggggag cagtttatca gtttgagaca gctagtcata
    15421 tgatcctttt aatcagcgaa aaaaacgcca gatatgatgg cgcttctatc aagcaaagct
    15481 tattgcgcag aggcattact gacgagcaag ccttggccag tcgtctggca tgctacgaag
    15541 ccttccaaaa gcatgatatg aaaatagcag atgatcctcg ggctctcttt gactggactg
    15601 ccaagcaaac ctatatcgcg cttgctaata tgatgaccac tgctgctttt atggggattg
    15661 actcttgtcc gattgagggc tttaactatg acaaggtaaa tgctatctta gcaaaacatg
    15721 ggattatcaa ccctgatacc gagggtatct ctagcatgct gtctttaggc tatcgcctgc
    15781 gcgatcccaa acactcacaa accagaaagc ccagagaaga ggttatttcc ttctttaact
    15841 aagccccttt tgccattgct cccaaagaaa gtgcaaagac agtcctttgc cttttctttt
    15901 tcataactgt cgaattatgg tacaatgtgt caaaagacct atggaaagtg atgcctatga
    15961 cattattatc tgtaattatc ccctgcttca acgaagaaga cacgattatt ccttatcttg
    16021 aagaaatgaa gcaaatcgaa gcggccatga ccagccaatt agcctttgaa tatcttttta
    16081 ttgatgatgg ctctacagat caaaccctga gcgtgctaag agagcttgcg gggcgcttct
    16141 ctaatgtgca ttacctctcc ttttcacgac attttggcaa ggaagctgga ctattagccg
    16201 gcctagaaga ggcaaaagga agctatatta cggtgatgga cgttgacctc caggacccac
    16261 ccgagcttct cccgctgatg tatagcaaat tacaggaggg ctttgatgtg gttgccacaa
    16321 gaagacagag ccgacaagga gagcctgcta tccgttcctt ttttgctaga ctcttctaca
    16381 gattagtcaa gcatgtctcc aacaccgaaa tcgtcgatgg ggtacgtgat tatcgtttaa
    16441 tgacaagaca ggtggtggat agtattttag agttgggaga ggtcaatcgc ttttccaagg
    16501 ggattttttc ttgggttggc tacaatactg cctatatcag ctttgacaat cgtaagcggc
    16561 agtacggcaa aaccagctgg aactttcttg agcttttgaa ctactcgata gacggcttta
    16621 tcaatttttc tgagatgccc ttaaccattg ctacctggac tgggacactt agctttttgc
    16681 tatctctgct agccatttgc tttattgtta tacgcaagct gctttttggt gatccggttt
    16741 caggctgggc aagcactgta tccattatgc tatttatcgg tggaattcag ctgttttgca
    16801 tgggaatcat tggaaaatac atttccaaga tcttccttga aaccaagaaa agacccgtct
    16861 acatcatcaa agaaaagaaa taacagagca atcatcaagg cccctatcag ccgccaatga
    16921 ggccgataag gactggttgc cctcatcatg acaagcacga caaaaagact tgatggtccc
    16981 aatcaaaacc atcaagtctt ttttagtatg tgaccttgcg tctgcctcgc acctaaaaag
    17041 acgagataat gtcataacca ccgtctatct actgacccca aaaagttgga caatttagtt
    17101 ttaagcaagg gatttagttc tgtattgcac aggactaagc aaggccatca gcttgtaaac
    17161 agacgcttag cggcggttca cactcttcat cacacgccga atgtcacgat cctgctcgcg
    17221 tcgcttgatc gattcacgct tgtcataatc atgctttcct ttggcaaggc cgattaacac
    17281 cttggcaaag ccatccttaa gataaacctt tagaggaata agggtcattc ctgtgccctt
    17341 tagctcatct gctaggtgct gaatctcacg ctttttgagc aataatttgc gcgtgcgctc
    17401 cggatcagca ttccagatat ttccctgctc aaagggagca atatgaacat tgaccaacca
    17461 ggcctcacca ttcttgattt gggcaaagcc gtccttgagc tggatacgcg cggcacgaac
    17521 actcttaatc tccgtaccgg tcaacacaat tccagcctca actgtctcaa cgatatgata
    17581 gtcatgacga gcctttttgt gttgcgctaa tacattacct tcaccttttg ccatgcttaa
    17641 ctccttttac gacctttctt tttagcagct ttttggtaaa atggtttctt tgcttttttt
    17701 cttgtcttct gctttgattt tggctttgag ggcttggact ccttactcct gctagccctt
    17761 gaagcagcct tttgcctgtg cttatgctta gctttagctg accttgtggt cttttcaacc
    17821 acatcatagt cactagccaa gtaatcaaaa tcaatgtcac ctgtttcctt gtcagccctc
    17881 accaatctaa cccgaatcgg ctgacctgct ctaaatacct ttcctgagcg ttcacccttt
    17941 aaggagagtg tccgttcatt atagtgataa tattcaggca aattggtaat atgcaccaga
    18001 ccttcaattg tatttggcaa ttcgacaaac atgccaaact taaccacact agcaatcacg
    18061 ccatcaaaca catcaccaat ataatctgcc atgtattctg cttttttcat cgcctcaacc
    18121 acacgctccg cgtcaattgc acgacgctct agctgagatg acgatactgc caattctgga
    18181 ataacctgtg caaaatgatc caccttctcc tgcgtgatct gattgtattc tcgaatcatg
    18241 cggtgcacca gtaaatcagg gtaacgacga atcgggctgg taaaatgcgt gtagtagtct
    18301 gctgctaagc catagtgacc atgattatgc tcagaatacc tagcctgctg catagagcgc
    18361 agcagcatca tattcaaaac ctctgctcca ggacttcctt ctacctttgc cataaaggcc
    18421 tgcaaggctt cttgagaaat cttattagca gttccctgaa tctgaatccc aaaggcacta
    18481 gcgtaatcaa taaaggtctg caatttctct gcctttggct cctcatgaac ccggtaaata
    18541 aatggcaagc cagcccttga aaaatgctca gcaacacatt catttgccgc tagcataaag
    18601 gactcaatca tgcgctctgc aacacctcgc tggcgcaaga ccacatcaac cggcatgccc
    18661 ttatcattga caataatcct agcctcctgc gtgtcaaagt tcaaggcccc gcgcttcaca
    18721 cgcatcgcct ctaagatctg atgcagctca accatagtac tcacatcatc agcaattcta
    18781 tcaaattccc taagcgcctc actgtcacct gcaatcatct gattgaccgc gctgtaggtc
    18841 attctaaagg ttgtgttaat cactgactga cacagctgat aatcaaccac atgtccctga
    18901 tgatcaatct ccatgatcgc tgactgggtc aaccggtcaa cctttggatt gagagagcag
    18961 ataccatttg acaaccgctc cggcagcatt ggcaccacac gatctgtcac gtaaacagag
    19021 gtcccgcgcg cagctgcctc acgatccaag gctgaccctt ccgtcacata gtaggacaca
    19081 tctgcgatat gaaccccaag ctcaacgttt ccattggcca atctcttgat atggatggcg
    19141 tcatctaggt ctttagcatc agcaccatca atagtgatgg tcgtttcttt gcgcaaatca
    19201 acacgcccca taagatcctg atcactcgga gcatctggaa tggcattggc ctcagctaga
    19261 acgtcatctg gaaacgccga tacaatatcc atagattcca aaacctccag cacatcaatg
    19321 ccgacatcat gctgatgccc aataatatca cacacagtcc ctacaaaata atcctgccca
    19381 gccttagggt attgcacaat atcagcctta atgatttcag taccatctaa ggcaattgga
    19441 gattttgcga tataaatcct ctgttgaatc ctttgatttt tcgacttgat gtagccagca
    19501 tacttagggt gatcatcatc taaaataacc ctaccaacaa ccgtctttaa agagcgctcc
    19561 acgatagcta ccacgcgagc ctctgctgct gtagccttaa gccgattagc tggtttttta
    19621 ataacagcct caaccctatc gccatcacta gcatacccca catcatcacg accaataaaa
    19681 atgtcgtcct cattgtcatc aaccgacaaa aagccaaagc cagccttatt ggcacgaaaa
    19741 ataccttgaa cccttatctc tggctttttt tgctgtggtg ctctaagaaa cacctcaccc
    19801 tcatctgaaa aagacaaaag tcccttgcct tccattttgg aaatggcttt aatcaggcga
    19861 ggaaagctcc tcgcatcagt catctctagt gcagccgcca aatcatgaat atttgattgg
    19921 ccatgctcct ttaaataatt cgtaatgttc tctatcatca tacctatctt ctatttctaa
    19981 caccatactt gatggttgtg ctcattgata aaaaaatgag ctagactaac tctgtcaagc
    20041 tcactcctta tttacttgat aaaatggcaa gcactaacgc aattcctaac caaaaaaaca
    20101 ctagaactgc tgtaaaacgt tgcataaaag cttcaaatcc gcgagctttt gtacgctcaa
    20161 acaaggcttc tgagccactg ctatcaaaaa cattgctact aggatttttt tgtggctgca
    20221 taaagatagc aatcacaagc aacactgata atactagcaa tatcgtaagt agtaagtcgt
    20281 acatgttaat tcctccactg tagtctcaat cattctaaca caaaaccaac taagattcaa
    20341 catgcagcgt tacttttctc tccttaggac agtatttagg aaccttaatc ttctcagggt
    20401 gacttgtttt atttttacta gtcaaataat ttttgctgcc gcaatggctg cactccaaat
    20461 gaatctttac tctcacatca tttccctaat cttactatat tttatcagcg tcataaggct
    20521 tcaaatcacc cgcagcttct ttattaaaga tatctctagt tattatagca tattatccag
    20581 taagaaaaca aactcaggac ttttagcaaa aaaggcttaa gcgccaacca ataaacattc
    20641 caaggctatc ggggaatatt ttctaatggt tattataaat catgaacaat tacctaacaa
    20701 agcaactcca aaacaaagat aaaagacgaa cattcacctt gctgctcagc tatcaagata
    20761 aacaatcctg atagcatcaa ttttctttag gtcctcagca atcggttgta atatcagaca
    20821 attcaggtgt tgattaaaaa aaacgaaact acggagacca attgtcagaa agctattcac
    20881 agcccgcagg cgtcgtgcta aagtattgtc tggaaaaaga aaggtttagg aatgattata
    20941 cctaaactca aaggagagaa acaatgagaa aaacaatgaa gaagatgcta gcagcctcga
    21001 cgctctgcat catcatgtca ggcagcttca tcagcggctc agctagagtg ttggcggaga
    21061 agtattatgg ttttaatgat ggcacaggag agcattcacc attccctgta tacgttactc
    21121 caattactaa acctaatagg aatactgcca aagttgtcta ctgtttcaat aaagatatga
    21181 agtggccaga aacttgggat aaagcagcac caaaaaaacc agataattta cctctatact
    21241 acgatatgga aggtactgat caattattca gtacatatgc aagtggacaa cttactccta
    21301 atgtcagtaa agtcttagct aatataatgg ctaaaggtta tccaaacaac aatgagtttg
    21361 ctcaccattt taaactcact cccaattccg ctgtaaaagt tactcaaatc gcagtttgga
    21421 ctgttacgga taacctaaaa aactattctc aatacagtct aaccagagaa gaggaagctg
    21481 cattaaatta cctaactgac aaaaatgggg acgactttag cgatagtatc aagttaaaat
    21541 tatacattcc acaaaatcct cgaactataa aatatcaaaa tcttctaggt tatgacctaa
    21601 tagttaaaac tccagaaaaa aaagataatt gtaaatgcac caaaatttat atagaagata
    21661 atggaaaaga tggctattat ctgtatattt attatgacaa caatgaaaat aatagatatg
    21721 actcggacaa agatagccta ttgcaaaaga aatacataaa aaatgggaaa gatgggaaac
    21781 caggaagacc aggggttcca ggacttcctg gccctgctgg acctcaaggg cctagaggag
    21841 acaaaggaga aaccggggaa cgtggaccta aaggtgaaaa aggtctagac ggtaagcctg
    21901 gtgaaaaggg tcctaaaggc gatacaggaa aagatggtaa ggacggacaa cccggacctc
    21961 agggacctaa gggtgaccct ggacgtgatg gaaaagatgg cgaacctgga aaacctggcg
    22021 agcgcggtga gaaaggacct caaggcgaac gtggacctca aggacttcct gggcccaaag
    22081 gtgagcctgg aattccaggg cctaaggatg aagatggaaa agatggtgct cctggacatg
    22141 acggacaacc ggggcctaaa ggtgaaaaag gggaccctgg gcaacaaggc attccaggac
    22201 ctaaagggga acctggacgt gatggtaaag atggagaaaa aggcgagcgt ggagagcaag
    22261 gacctcaagg cgaacgtgga gagcaaggac ctcaaggcga acgtggagag caaggacctc
    22321 aaggcgaacg cggggagcaa ggacctcaag gcgaacgtgg ggagcaagga cctcaaggcg
    22381 aacgcggaga gcaaggacct caaggcgaac gcggagagca aggacctcaa ggcgaacgtg
    22441 gagagcaagg acctcaaggc gaacgtgggg agcaaggacc tcgtggagaa aatcctactc
    22501 ctaccccaga tccaatgcca caaccagaac cacaaccaga accacaacca atgcctgatc
    22561 cagcacctaa accagaatcc aagccagaac ctaagccgat acctcaacca gaggttaagc
    22621 ctcagccaga gacaaaacct caacaaccaa acaagccatc aaccattact agccaatcta
    22681 gcggcaaatc actgccaaaa acaaatgaca ctggcagctt gatcacagca tttggtacag
    22741 gcttactcac tcttcttgga ctaggcttcc tagcaaaacg caaaagaaag caataattaa
    22801 aacactaccc atagcctttt aatcattggc tatcaactag ataacaaaaa gcttatcgtt
    22861 ttactcctaa cgataggctt tttcgcattc cctattgctt ggtctcaata ctatttttcc
    22921 agctttaggc tggttttgct aatccaaaat aatatcagac aatttccgtt ttaattaaaa
    22981 aaaaaaaaaa acgaaactac ggacgccaat tgtcagaaaa tggttcacag cttagagtca
    23041 ccatgttaag ctattctacg aagaagaaag gtttaggaat gactatttct aaactcaaag
    23101 gagagaaaca tgagaaaaac aatgaagaag atgctggcag cctcgacagt ctgcatcatc
    23161 atgtcaggta gctttatcgg cggatcagcc agaatcctag ccgagcagta ttatgggtgg
    23221 aatgatggaa caagagtaaa atcacctttt ttcctttatg ttacgccaac aaatgaaacg
    23281 actaggaaaa ccggaaaaaa tggtacaata gtctattgtt tcaacagaga taaggaatgg
    23341 ccagcaaatt gggaagaagg aagatcctta gaactagtga atgctgaaac agcttataaa
    23401 ttacccatct ataataaatt actaggtaca actgattcct ttactaaaaa tgctagtaaa
    23461 ccaagagtat ctggagatat tggtaaagcg ctaatagctg tactgaaaaa tggttatcct
    23521 aataaaaatt tatccggatt agatgacact aaaagtcgaa tactaactca actagctatc
    23581 tggtatttca gtgatagtta taataaagat tattttaaac aaaattatga attaactgat
    23641 caagaaaata actctcttat ggagctgatt aaagtcggtg aggaagcagc tcaaaaacaa
    23701 gaaaaaccag aatatcattt agatatatat ataactacag aaaaaaatta ttaacataaa
    23761 ccttatcaaa acctgcttgg ttctactcta attcctaaac ttgaccctaa gcctgaacca
    23821 gaaccagatc ctaagcctaa gccagatcct gaaccaatgc ctaaaccaga gcctaagcct
    23881 gaaccagagc ctaaacctga acctaagcct gaaccaatgc ctgatccggc acctaaacca
    23941 gagcctaagc ctgaaccaat gcctaaacca gagcctaagc cagagacaaa acctcaaaaa
    24001 ccaaccaagc cgtcaaacgc tactagccaa tctagtggca aagcactacc aaaaacaaat
    24061 gacactggca gcttgatgac tgcacttggt acaggcttac tctctcttct tggactaggc
    24121 ttcctggcaa aacgcaaaag aaagcaataa gctgaataag ctaatgcaag acagcactag
    24181 tatataatgc gtgcatggtc catctaatgc agcacaaaag ccttatcgca ccacgaatgg
    24241 gtacgataag gctttttgca tacgctatag aagctccaaa accactagac tagggcaaca
    24301 gcatggcaag gcttacgcct ctaaatcatg cagagcctta ctaatctgtg tctctaaagc
    24361 ctgaaaatca ccagtattat caatcactaa atcagcataa gctcttttct gagacatcgg
    24421 cagctggcta gcaatccgct gcctagcagc tagctctgtc aattgattac gcttcatcag
    24481 gcgcttgagc tgagtctcct catcaacata gagcagccaa atagcgtcaa accaatcctg
    24541 atagcccagc tcaactaaaa gcggtaaatc cataaagaaa atagcctctg tttgagatag
    24601 ctcctctttt tgcttggcta aggcttccct aatgatagca ttctgctgct gggaagattt
    24661 cgccatattt tccgaatgag caaacagcag ctccgctagc ttaggtctgt ctaattgccc
    24721 cgatggcaat aaaatatcct gtccaaaggt ctctagtagg acctgataaa gcttgccgcc
    24781 ctttttttgc agctcatgca ccacctgatc cgcatcaatc acctggtagc ctgcttgtct
    24841 gataagtgcg acagccgttg attttccgga ggcaatacct cctgtaatgc caattacctt
    24901 tgtcattgct tctgacacct aggacagaca tgtgtccctc ttcctccaac cttgagcttt
    24961 acaatggagg tcccgcagcg ctgacagggc ttgcctgttt ggccatagac catcaaataa
    25021 tgctgcatac taccattcat tcctaaggta ttctgatagg ttctaaccgt cgagccaccc
    25081 ttttcaatac ctaattgtaa aatacgaatc gtttcatcat gaatccgttt gatttctgcc
    25141 tttttcaggc tagcagatcg acgctcaggg tgtactctag ctgcccatag cacctcgtcc
    25201 acatagatat ttccaagacc agccactaaa gtctgatcca aaagatgagg cttaatggtc
    25261 tttttagagg ctagcagagc agcctcaaag gtcttcaatt gaaaggtctg cttcgtcggc
    25321 tcaggaccaa gctgacgctt ctggaaaaaa gcagccagct cagcctttgg tagcaaatca
    25381 aaggttccaa actttctcac atcttggtaa accagcgtgg agccatcagt cattgtcaaa
    25441 aagacatgaa aatgcttatg ctcaggtacc gtatcaggaa acaagaggta tttcccctcc
    25501 atacgcaaat gcgagatcat aaccagctgg ccaaagtcaa agagcaggta cttcccgcga
    25561 cgatctaccc cttgcacctg ctgcccaggg atcgtcatca caaaatgctc aaggtctgtt
    25621 ttgaccatct tgggcaccct aactgtcact gctgcaatct gcttgccaac gactaagcgc
    25681 tcaagcccgc gtcgcactgt ctcaacctca gggagttcag gcataattaa agataccaaa
    25741 cgcgctaaca aagaaaccac ataaccaaaa ccagcagaac cagccagttt tagcactctt
    25801 tactcagtct caatgttaca aacacgcttc ctttctataa gctactatta gaaagcccca
    25861 cccaaaacct caataagctt gagcacaaag gactatcctt tgataagaac tgttatcatt
    25921 cttattttac gcataatcca taaagaaagc aactctcacg aacagccttt gcagtcactg
    25981 ccgctatagc atcagaaaag cacatctcgc ccgccaatcc agcaagcaaa gacaaagccc
    26041 ctgagctagc ctattgtttg ccagcccaag ggcacgttgt ggcctttagt gtctgtaaat
    26101 agaaaaccaa gcaatgctgc aagcctcaac tgacaatgct aggtctgatc agtcctgtca
    26161 tcagcttgcg gataatctat actaattggc ctatcaacaa gacggatact atcctggtaa
    26221 acaccttctg tttcaaaaat aacaatgtca tttaatccct tgttgaaata gccctttgga
    26281 atataaaggg ttaataaggg acccacttcc caaaaacgac caatagggtg attgttgata
    26341 aagacacaac ccttcccaaa gccagtcata tcaatatagc ttgcctcagg ctcatgacat
    26401 tcaaattgat aatgataaaa gccgggctgc ccctcgtaaa aatcgccatc aaaacaaagc
    26461 tgagacaaat catcaagcgg cagacaatac atctcccaat tggtcacaaa gtgcaagtca
    26521 gccatcatac cacgtcctag acccttactt tgactaggtg ctgtcagctt gtgcccataa
    26581 ttgacccggc ccatattttc aattaaaaca tcgacctgac tcaaggcatg ctgctggtta
    26641 atgatgatat catcaccaat cgtctcctga tactgtgttg caaccttttg accatctaaa
    26701 aagacctgtg ctctatctct actatcaatc aagcgtaaac gctcgtcctc acgcttatcc
    26761 ttcaaaagat gtgtccgata caggatatag cccgttgatt gccctaaagc ctctatgtta
    26821 ctaggatagc aagcagtctg acagctgctg atgtgctcca gcgtgctaaa cagactaacc
    26881 ttgtccttca gaccaatcag aggcagtgac atcaagggct taatcaaggg aggagtaacc
    26941 tctatctctg aaagctccgc ggtcagacgc ttttgaatcg cgtaaaactt agctgtcgga
    27001 ttgccagcct catctaggat agcgtcataa tcataggagg tcacctgcgg aaggtccaat
    27061 tgctttctgg cagagcagcc attcataaac ccaaagtttg ttcccccatg aaacatatac
    27121 aggttaatac tgccctgcgc caaaacctcc atcactgcgt cagctcgctc ttcagggtcg
    27181 cgtttgatga tgggctcatg ccaacgattg aaccagccgt cccaaaattc catacacatt
    27241 aaaggccaat gcttgccatg ctcagaaaag aaggcctgca tgtcagcaaa attctcctgt
    27301 gcccttgagc caaagttgcc agtcacaaag acatcatctt caatcagact accagctcta
    27361 agagtggctc gccaaggacc atctgctgta aacaagggcg cactgaggtg ctcctccata
    27421 aagcccttaa cagctgttaa ataggcctta tcctctccat aggagccata ttcattttca
    27481 agctgaaaca tcaaaatatt gccgccctgc tgccattcat gccttgctag tctcggcagc
    27541 agctcctcat aatagcgcct cacataggct aaatagacag gatcagacga cctgatatga
    27601 caattctttg tcagcagcca agcaggtagg ccaccaaatt cccattctgc acaaatataa
    27661 ggactaggtc tgacaatagc atagagcccc aattgctgcg ccagcgtcaa aaaggcttcc
    27721 acatctaatt ggccagagaa atcatagctt tcctccctag cctcatgtaa attccaaggg
    27781 acataggtct caaccgtatt aaatcccagt gcctttaaat tataaagcga atgataccaa
    27841 tcatctgggt gaattctaaa ataatggata gcccctgaca ggatttgcag cgatctacca
    27901 tctaaataaa actgatctga aatctgaaaa cgttccaagc ttaattcctc acttattatt
    27961 gctattagcc tactaggcct cattgctgag cggcttggaa tggcccattc tagcaacagc
    28021 gaacaggcca ttcagcagac aggctaactt atcttatggt aacaattgta aacactatct
    28081 acagtctgac tcctcatgct atgctgtcac agcagcagga taagagacag tgtatgcctt
    28141 gtcatctgtc aatctaatcc catatttggt ttcaacaata gtatggtcaa actgcggtaa
    28201 aacagttatc ggtccttcag gcatactctc cagagacaat tcaaatatcg ctgtgtctgt
    28261 gccatctcct gaaacatagc tggcaagctt atctacgcca tttacagtaa ctgctaactg
    28321 acgatcacca agaataaaca tcggttgatt aaaggtcatc tgaatggtta tgcttacttt
    28381 gccattttgc tttggagctg ctgacgttat tgttacttct tcaatttcag ccttatcctc
    28441 acgaaactgg tctgagatca tctgcttgat attaaaggtt gaataggtga tctgaccact
    28501 atattcgtat aacaaaccaa ccctctcgtc gtctagttga accaagctag agtaagcaaa
    28561 acgctttggc tcaaaaatgg ttgaagcgac ccaatgaatg ctatcgtcct ctaagacctc
    28621 accgacacgc agaatccctt tcatgcgctg atttctaatc gtcagttgct cacctgaggg
    28681 ctctcctaaa ggattggata aaacaacata ttctttgcca tcaaccatca tatgaatagc
    28741 tgacaaattg acataaggct ctgggaggtc tgtgattgta ggattatcgt cccaagtcat
    28801 accatagtct gtgcttctgg caataacgat tgtctttccg gtattgcgca taaactgtaa
    28861 taagtgacca ttgtttagct gaatgatttg attttctgtc aattctgtga ctgatgtatc
    28921 aaaatcctta gaggttgttt gttggttatg accataaatt ctgccatcat ttggtgattc
    28981 acctcgttgc catgtttgac cgccatcatc actaaaaata ttagcactgc tttgacgacc
    29041 tagactagct gatgtcgcat tttgttgatt ggtatagtaa atcgggaaaa ctaaccgttt
    29101 cacctgctca ccctctgcat tgactgcgtc tatttcaatg ccagctgcgg cacccgtacc
    29161 taaaaatccc atccagtctt cttttatttg tggggtaata tcaagaggtg tggaccaggt
    29221 ttgcccttcg tcttcactgg ttagcagcca taaaaagctg gtcatgtaag taaatagagg
    29281 agctgtttgt gagccttctc tagtgatgcc ttgcttagtg cgaccacttc tcagataaat
    29341 attccctagt agaatatcct ctcctgcctc tgtttgatag aggttgccgc gtgtgctaaa
    29401 ggctgtctca aaattgccct catcaacata catatctgtc tgatggccac tctggtcata
    29461 gacgatacca ccttcacgca cagtgtattt attattgtca aaatcataaa gatttaaata
    29521 atactgaccg ttaatcaatt catatcctga gcctgcttta gaagcaacag caccctgtga
    29581 ctcaggaaag acatctacca gcaaataaag cttgccagaa gcgtctgtta gcaaggtgga
    29641 gtctattgaa aaagcagatt gagtcatgtt ggtattccaa tcagccaagc tatattgtgt
    29701 tgtaaaataa ggctgagttg gcatatctaa gaccgtaatg ttattactcc aggttttgcc
    29761 atcatcatgg cttatcctga caacagttgc aacatctccc cagtcattgt agtgcttctt
    29821 tcttgcatct gctgcggcta tcaaggttcc tgatggcgtt ttgacaacag agggaatccg
    29881 atattcaaag accccttcat catatttgtc ccaaacattc gtcttttcac cagtaactgg
    29941 tcgaagggtt ggctgatgag ccttggcaat atctgtcaga tcatacacat ctgtatcaat
    30001 cagcacctga tcaaccagtc cctttaaccc ccagtgaagg accgactcac catcataggt
    30061 gcgtttcaag cctccaattg ttagcgtatc agcagaagcc ttccaaggta attgcttcat
    30121 aaacccagca aagtcagctt ccccatataa gtcaccattc aagtaaatct ttagcctaga
    30181 ccctgtaaag acatagctga tcgtctgcca gtccgagttc gttaataaat taaagcctga
    30241 gccaactttt acaatcggaa cctcagctcc tttaaattca agacctattt tattgttttt
    30301 aggctcgata aagaaagagg cgtattcatt agctgatgct tgatttgaga tcgataacaa
    30361 ggccaagggc gatgagcttc tcactgttgt atcagcagta tctagacggt atctgattgt
    30421 tacagttcct tgggttaggt tcatcacatc gtctagctta ccaagagcct cgtcatctgt
    30481 tacggctgct ttttctgctg ttgcgtccaa aatagcattg cctaaatcaa ctaaaatgga
    30541 tgcttgatct gagattggct gatctgagat atagcttgct tctatgcttg tataaacagc
    30601 tcgtccgcct tctgtggtgt atttgatctg ataatgctct gcacttccca agatctcctc
    30661 tggcgtaacc cattgccaat tggctggcag ggctactgta gataagggtt ctcccttctt
    30721 accaatcaga ccttctttag gtaatacagt taaaatagct acttctcttg caatcttagc
    30781 agttggtgtt actgttgagc ctaaatcagc attgtaagga acagcactat agtaaatgtt
    30841 ataaatacca ggagctagct cagacaaggc tgacaaatca tctcgaccag cagcctgtaa
    30901 agcagcattg gtatttccac ccttgttagt aaacaagtat tcattttcaa ctgaaaaatc
    30961 aaccacatag ccttcctgat cagtggttac agcttgagct aaatcaggac tggttccctc
    31021 tagcatggtc aaatccttga cccccttgag aactggctgt gaggcataat aagcttctga
    31081 ggctgctttt tgctcagcat cttggtaata acgcacataa tcaatcacaa aggccgtctc
    31141 atctgaagct agatagtagc ctgcattttt actccaattg cctccagtag caaggttaaa
    31201 ctgaaggtat tgaggcttat taaaggcagc tgcggcagcc tctaagcgat catcaccggt
    31261 taaatacatg gtattataaa caatcccatc aacataccat tcaatcttat ccggatacca
    31321 attaatacca aagatatggt agtcatcata aaagtcatca cttaatgtca gattgccacc
    31381 caatgctgtt gggctatagc ttccatcttt gtctgcatca cccttgatat agtaaaaatg
    31441 aggggtcccg taaactgttt tgttgctttg atcaccttcg gcaagctcac cctcatgctc
    31501 tccgttagga gcaccgatta gctccataat gtcaagctca cctgtgcttg gccagccata
    31561 gccttgagtt gacgcaatat caccatctaa ggtaaaatca gcccccaatg tccaaaaggc
    31621 tggaaaggct cccttaccct tgggaagctt ggccctagct tcgatacgac catataaaaa
    31681 ttcttgcttg ccaaccgttc gtacgcttcc tgaatcataa atgacctgac gtgcgcttgt
    31741 tcctcctcta ggattggcat aacggtcctc cccataacgc tctgtgacgt ttaaaacaag
    31801 attgccatta tcaagataga cattctctgt gctgtctgtg tagtgctgct gctcattccc
    31861 gcgaatactt cccaattcat atccccagtt ctcttggttt aaccgatctc ctgaaaactc
    31921 atcctgccaa atcaattcat aatcattttc ctctacgaca ctcacgttat caatactagc
    31981 agaggcagcc aaggcttccg gagaagaggc ttccaaccat ttgactaagc caacaaaggt
    32041 ttctgaagtc gttgctgtaa aggagagctt gatatgtgac caagtaccgt ctgtatctgt
    32101 gaggctgacc tctttgataa cagggccctg aagattgtga ttggactctt tagcggtaag
    32161 gtataagcca ttatgaggtg tgtcagcttc aaccttcaca tcagcctcta gcgtataggt
    32221 tttcccaacc gttgtagaca ccttttgaag gatatgctca tctaaagtgc cgcttgttac
    32281 ctcagcatag ctattaccat tctctgttgt gaggactgaa tgacctccct ctctatattg
    32341 ccactgattc ttattggaca cataatcatt gtcaaaacca ccattagcca ccttattgag
    32401 ctcaatcgga gcgttagact tctcttcgtc tgctgtctga tcagcagcat tgctggtcac
    32461 agcattagct actactgcct catctactgt cgtctcctct gagactacta aggcctcgct
    32521 atctgtatct gtagcttgag gctcctgctc atggcttatc tctgttactg ctgctttcgt
    32581 aggctgctgc aggcttacct ctgaaacgtc atcagcataa acagccactg gcagaccagc
    32641 agcaagacca atacccacac acactgaagc aacaccgaca ctaagctttt tgatggcata
    32701 ttttctaatt tgctcttttc cgataggatt aaataacatg tttatttcct cacttatata
    32761 tacatcattt ttaaacacaa tagcttttca aaggcccatt tagcctaatc cagtgctggt
    32821 caggctaacg accttgttat aaaaacgctt tcaattcagc gcttaaaaga agatatacca
    32881 gatgaaaccg atatatcctc tcacaaagtg actaacctgc cttttcaagc tcattatcag
    32941 ccatcttaac aaatggaagg taaatcaggt ttgccaaggc caaattgaca agcgatagca
    33001 caatagcacg ccaatcaaaa ccagttgaaa agaagccata caagacaggc ggcattaccc
    33061 aggtcacatt ttgcgtaacg ggtgcaacca agcccagact agttgcgata taagcaacac
    33121 ttgacataac agcaggacaa acaataaacg gaataaacaa caaaggattt aaaacagttg
    33181 gtaaaccata catcactggc tctcctatat taaacaatac aggagcaaca cctagcttag
    33241 ccacctcacg atagtgttca tttttagact tccagaaaat agcaatcaag agccctaagg
    33301 ttgcatacca tacaaagaac actcgtccaa agataaggaa tcgcctcatg cttttgataa
    33361 gcctccaaat tagccaagag ggcaacacca aatactccct ccatatttgg cgccataaca
    33421 ttgccgccat gaatcccaaa gaaccagaaa aattgggtca aaacagctac caaaacaaca
    33481 gcaataaagc tttgtgataa gcccaaaagt gggatttgca agaccttata gatccaatca
    33541 atcatcaaag aacccgttag cttttcaaag acaaatgtta aaatagctac gctatacaag
    33601 gcgcaaaagc ctggtatgat agataagaag ggcttggcta cagcaggtgg cacactatct
    33661 ggtaatttaa ttgtccaatt ttttaacatt aatttacaaa aaataataga ggctaaaaag
    33721 ccaatcataa ttgctgtaaa ataaccattg gagttaattt gcgcaccagg caataggcct
    33781 gagatggtca cattaagtga gctgccgctg acagtaacac cactgtcctt aaaagccgtc
    33841 acaagatcaa cacccttgag acctgacgcg tcaatgctag aggtaacaga atccccaatc
    33901 gcaatcacaa aggcagctaa agaaaccaaa cctgatgaga gcgtatctgt cttataaagt
    33961 ttagcgacat taacccctaa gcaatacaca aatagcaagg acacaatcga aatgcttccc
    34021 ttaaagacaa ggttgttgat ggttacccac cattggaagg cctctgtaat gccttgcaag
    34081 ccaaattggt ctggaatatc cactaaaaag gcattgatca acagggcaat agagcctgtc
    34141 atcacaaccg gcatcgttgc aataaaagaa tctcgcaagg ccactaaaaa tcgttgatta
    34201 ccaatcttcg tagcaattgg cagcagcttt tgcgaaagaa agttcatata gttattcatt
    34261 catagctcct taaaacaatc ataaaacagc taagatagag cagtaaaggc tctctctaac
    34321 agcttagcct tcatttttag tttgctcgct cgcctgccat cttctttcca cattaataat
    34381 aaacggcaag taaagaagaa tatctagaat aattaaaaca agctgtagga ctgaggcttg
    34441 ccagctgccc gttgccaaaa atcctgaaat aacaggcggc atggtccacc ccggatcagc
    34501 ataggtgcca ggtacaatgc cagaagcaaa ggcaaaataa gcgacaaaca aattcataac
    34561 aggtgctagt acaaaaggaa taactgtcaa tagatttaaa acaaccggta agccaaacat
    34621 ggtcggctcg ttaatgttga aaaaccctgg aatcaaggtc aatggtgaca agacctttgc
    34681 ctgctgacta gccttgcgac gacgtgctaa ccaggctaaa gccaacacca agccaatggt
    34741 tgcaccagct ccgccgataa aaacaaagtt atccataaag acagacgtaa agacatgcgg
    34801 caattcctga ccagccttat gagctgccat attttcagtc aagttagata accagatcgg
    34861 cttcataata ggattgttta ggacatttcc accatgcaca ccacagaacc ataaaaagcc
    34921 attaagaaga acaacgataa aattaccaaa taaggtactt cccagcaagc caaatggaac
    34981 tcctagtacg gacttaacaa tgtcatggac atttggcagg ctaaaatgat ccaagaaagc
    35041 ataaacagca agccaaaaca caataatcac cgctccagga ataatggcgc taaagctttt
    35101 tgatactgca ggcggcacac cctcaggcat cttaatccga atatcctttt tcataaacca
    35161 ttgataagca tagccattta ccaatcccaa aacaatggca acaaacaagc cgcctgatga
    35221 aaggtaagaa ggcgcaatac ccgctacctc acccaaggct ttaccagatt cattgacaaa
    35281 tgaaacagta aatggggtca ctgttaaaaa ggcagagata ttaataatcc cagcagaaat
    35341 cccgtctgcc ttatactgct tagccaagct ataagaaatc ccaaaggccg caaccaaggc
    35401 aatcagatta aagctcgaat ctactccctt ccacagatag gtagagacac caatctcacc
    35461 aagccaagct tcccaaccag gaatcggcag gctagcaatc accattaaaa aggacccaat
    35521 caaaatcaag ggcatagcgt aggtgatccc atcacgaata gcaataagaa agcgattgct
    35581 tcctaggcga ccagcaactg gaacaagctt ttgctggata aaatcttcaa atttagtcat
    35641 tgttacctcc ttgtgacgtt aacctttcat aaatagatac tagctccctt gccaaatcaa
    35701 caaaggtaat actagtcatc aaatgatcct gaccatgaac taatagtagg cttactggtg
    35761 tagcatttcc ccgtgcctct tgagttagca tatctgtttg tgcatgatgg gcctgcacca
    35821 atgccttatc ggcctgcttt agactttcct gagcttgatt gagctctccc tttttagcaa
    35881 aagcaatcgc ctccatcgca agcgacttgg cactaccacc atgcatgatc aggcccataa
    35941 tcgtctctag ctgcttatct tccatgacca ccacctattt catcaaactt tcagctaagg
    36001 caataacctt atcaccattc atcataccgt aatcaaccat tggcacaacc gccactggaa
    36061 tgtccttttc tgccaagctt tcttgaaatg ctgacaattg ataagcaacc tgtggcccta
    36121 ataacaccac atcaacagga tggcttagag cgtaatcctc tgcctcagtc aatggcaatg
    36181 caaaaatatc tgcctcaagc ccccgattgt cagcagcctt ttccatcttt gtcactaata
    36241 gactggtact catacccgct gcacaggcca acataatttg ttttttactc atgatcttct
    36301 cctttatccc aaatcctaac gtcgaataga gcgcgacatt ctcacaatgg tatgtctttt
    36361 tcctcggata gcgtcactaa gagcaaagat attttccact ggcgcaatcc cgctatagcc
    36421 agcatctccg atatgatgaa tatcgacacc acagatttta ttgcgaatag caatgtctcg
    36481 aacgatcgta gtatctgacc cttcctgact cgttccaata gctgacataa ctagagcatc
    36541 gtgagcatgc acctcctcaa caatagctct aaggtcaccc tctgtaaagc caggaactgt
    36601 cccaacagca ggaactaaaa tcacatcagc cccagcctcg ataaaccgcc gaacagtttc
    36661 taagtcaatc accgcttcat tagagccagc agcatgcatc tttccagcaa taatcaagcc
    36721 tgaaaaatag tgcttggcct gttgaatagc tctttcaatc tgattattgc taacaccagt
    36781 acctggattt cctgtcaagc aaacaaagtc aaagcccaag gcttcaatct cttgaaaggt
    36841 cttagctgtc gcctgtcgcc cttctactag ctccaagcgc ttttcagtca tgtcaacgtc
    36901 caaatcaatt ggttctaaat taacaccaat tggacgcccc accagacgac gcagctctaa
    36961 aataggctga tcagtagcag gtagaccaga tatttgaaca tcaaagacat ctacacaatt
    37021 cagcaaaatc aaatcagcac taaaggctgc ggcaacctca gcgttcgtaa ggtcatctcc
    37081 agtccaagag ggtcttggcg ctacattttc tgagacaatg gtacgtccct cgcttgcctt
    37141 aatggcttgc tttagctcta acgatgttaa ctgtagcatt tctgagctac tagcactcaa
    37201 taatcgtgtt ttcatcgctt ctcctttatt tttattttaa aaacattaac aaaagataaa
    37261 taagatttaa ctcttatttg tttacttttt ataaacaaat aaagtatatt ctatttacca
    37321 atatttgtca acgttttcag gcaggatttt taattctttt ttggtatgat agaggtacga
    37381 taatagaggt tactatgaag acggataaac aacaagagct ttacgcaaaa attttagata
    37441 ccatttatgc ccaacggcct atttcacgca ttgatatttc aaagctaacg cacatcacac
    37501 ctgctacagt aggggctatc actaaagagc tgctagcaca ggggtggata cacgaaatcg
    37561 gagagctgac ggaccactcc gttggccgca aaaaaatatt acttgatgct tcggctaacg
    37621 ccttttattt tgctggtgtc gaattgtccg aaaagcattt ctatttggtc attacagata
    37681 acctgggcac catctatgcc aagcacaacc aacagatcga cccaagcatt tcctcctact
    37741 acaaagcaga ctatatctct gagctgattc aagccttcct caagcagcac aagcactatg
    37801 atgtacaagc cataggaata gcactgcctg ggcattacga tcattccacc tccagctcaa
    37861 cgcatattaa caccaacaat cccatctggc agcaggtcga tttaaccgca attgcgaagt
    37921 ccttccctat tccagtggtc tttagcaaca atgctcactg tatgattatt gccaagcgct
    37981 tatacgagcg tcaggcacat aatcacaatt ttattttctt tcatgtcgga cgaggcatgc
    38041 actgctccta tatgtataag ggggtcattt atagccgtca caatgctgtt gttggggaaa
    38101 tcggacatac cattgtcaac cccactggag agctttgtga atgtggcaaa aaaggctgtt
    38161 tacagaccta tgccagcaat gcctggttgc tcaaaaaagc aaaactgcta catcagtatg
    38221 cccccaattc tcatctaaga agccttgtcg ataaggcctg tgagctcaag ctagaccatc
    38281 tcttgattgc ctatgagctt ggtgatgtcg gggtgaccac gctcattcac acagctattg
    38341 attaccttgt tttatccctg tctaacctct ccttactgat tgataccgag caaatctatc
    38401 tccatggcag atttatcagc catcctctta tatcctccaa aattctgcaa gccctgcaaa
    38461 atgacattaa gcttcttagc aatcaaaaaa agccagaaat cattgtcatg cctttttctg
    38521 tctataatgc cgctgtggga gctacaggct tatgtataga tgagctttac ctcaattata
    38581 aaaacaaata tgattgataa cccccacacc aatatcagct aaagctttaa agcccatttg
    38641 agaagctatt tctcaagtgg gcttttgcat tatgcgactt tcagtccatc tcgctccgca
    38701 ggtgcgagac aaatgataac cataaaaaaa gagaggcact tggttctctc tgttctatcc
    38761 taatgcccca tttgaaactc accagcaaaa tactctgcca gcatcagtct atgcttgtct
    38821 gagattgaag acagctctgc aatctcttct ctagaaaaat aaccgagcct taaggtttca
    38881 tcattttgat aatcagtgat agccttatct gccttggcta taacctcata aagcatcaca
    38941 acggtctgaa ccttatcacc atttggatag gtctcttcaa aattggtata aacattcaac
    39001 aaccgtaaag gctctactgt aatccccgtc tcctcataaa attcacgcct gcaggtttca
    39061 gcagaagact cacccagctc catggcacct cccggaattg cccaggtttt cttatctgca
    39121 cgtagctgca aaagcacctt accttcggca ttggccaaaa taccaccagc aaaagtcaga
    39181 ataatgttat catgccccac ctttgagcga atataggaaa tatagtcctg tgtcatcgta
    39241 actcccttca ttgccatcat aagattaaag ccagtcagct ggcgcaattg ctgctttttt
    39301 gccaaccaat aagcaatgca ggctttgtct cttgtccttg ataggctggc aaagcatata
    39361 gccctaattt ttcaacctga ttatatcaca ctttttaaaa gccagaaaga gactcgaatg
    39421 ccaagtccct tttctttcaa tctataacca acctcagaaa aactcagaca agctacgata
    39481 acttttttaa tgtcttcttt ggccaatggt ttgcgactgg tcattgaatt actttcaata
    39541 ttatccccat catcacatga taaccacaaa taaacacgta cttgtgtcat tgccttctcc
    39601 tcaatcagta gtaggtacct actgtttttt tgattgattg tacctatagg tgtttttttc
    39661 cttcaaaatc tttaaataaa atacccttta taa
//
LOCUS       DARYJX010000019        39226 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYJX010000019 DARYJX010000000
VERSION     DARYJX010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39226
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(93..464)
                     /locus_tag="TU257_000964"
     CDS             complement(93..464)
                     /locus_tag="TU257_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833983.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TU257_000965"
     CDS             683..1321
                     /locus_tag="TU257_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL0833984.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TU257_000966"
     CDS             1517..2053
                     /locus_tag="TU257_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0833985.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TU257_000967"
     CDS             2916..3320
                     /locus_tag="TU257_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL0833986.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TU257_000968"
     CDS             complement(3376..4860)
                     /locus_tag="TU257_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL0833987.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TU257_000969"
     CDS             5219..6442
                     /locus_tag="TU257_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0833988.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TU257_000970"
     CDS             complement(6532..6891)
                     /locus_tag="TU257_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL0833989.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7769
                     /locus_tag="TU257_000971"
     CDS             7056..7769
                     /locus_tag="TU257_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0833990.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEALKA"
     gene            complement(7848..8675)
                     /locus_tag="TU257_000972"
     CDS             complement(7848..8675)
                     /locus_tag="TU257_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL0833991.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8936..9064
                     /locus_tag="TU257_000973"
     CDS             8936..9064
                     /locus_tag="TU257_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL0833992.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9118..10431
                     /gene="obgE"
                     /locus_tag="TU257_000974"
     CDS             9118..10431
                     /gene="obgE"
                     /locus_tag="TU257_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL0833993.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10552..10710
                     /locus_tag="TU257_000975"
     CDS             10552..10710
                     /locus_tag="TU257_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0833994.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10763..11467)
                     /locus_tag="TU257_000976"
     CDS             complement(10763..11467)
                     /locus_tag="TU257_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL0833995.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11802..13202
                     /locus_tag="TU257_000977"
     CDS             11802..13202
                     /locus_tag="TU257_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0833996.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13212..14306
                     /locus_tag="TU257_000978"
     CDS             13212..14306
                     /locus_tag="TU257_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL0833997.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPREVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14412..16406
                     /locus_tag="TU257_000979"
     CDS             14412..16406
                     /locus_tag="TU257_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0833998.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16420..16737
                     /locus_tag="TU257_000980"
     CDS             16420..16737
                     /locus_tag="TU257_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0833999.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16734..17069
                     /locus_tag="TU257_000981"
     CDS             16734..17069
                     /locus_tag="TU257_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0834000.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17069..17503
                     /locus_tag="TU257_000982"
     CDS             17069..17503
                     /locus_tag="TU257_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL0834001.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17578..18957
                     /locus_tag="TU257_000983"
     CDS             17578..18957
                     /locus_tag="TU257_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0834002.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18954..19106
                     /locus_tag="TU257_000984"
     CDS             18954..19106
                     /locus_tag="TU257_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834003.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19263..20003)
                     /locus_tag="TU257_000985"
     CDS             complement(19263..20003)
                     /locus_tag="TU257_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0834004.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(20003..22168)
                     /locus_tag="TU257_000986"
     CDS             complement(20003..22168)
                     /locus_tag="TU257_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0834005.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22360..24351
                     /gene="uvrB"
                     /locus_tag="TU257_000987"
     CDS             22360..24351
                     /gene="uvrB"
                     /locus_tag="TU257_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL0834006.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24690..24833
                     /locus_tag="TU257_000988"
     CDS             24690..24833
                     /locus_tag="TU257_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL0834007.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24845..26383
                     /gene="dltA"
                     /locus_tag="TU257_000989"
     CDS             24845..26383
                     /gene="dltA"
                     /locus_tag="TU257_000989"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL0834008.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26380..27627
                     /gene="dltB"
                     /locus_tag="TU257_000990"
     CDS             26380..27627
                     /gene="dltB"
                     /locus_tag="TU257_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL0834009.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27645..27884
                     /gene="dltC"
                     /locus_tag="TU257_000991"
     CDS             27645..27884
                     /gene="dltC"
                     /locus_tag="TU257_000991"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL0834010.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27877..29130
                     /gene="dltD"
                     /locus_tag="TU257_000992"
     CDS             27877..29130
                     /gene="dltD"
                     /locus_tag="TU257_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL0834011.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29164..30138
                     /locus_tag="TU257_000993"
     CDS             29164..30138
                     /locus_tag="TU257_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0834012.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30679..31938
                     /locus_tag="TU257_000994"
     CDS             30679..31938
                     /locus_tag="TU257_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0834013.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32111..33811
                     /locus_tag="TU257_000995"
     CDS             32111..33811
                     /locus_tag="TU257_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL0834014.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33840..35972
                     /locus_tag="TU257_000996"
     CDS             33840..35972
                     /locus_tag="TU257_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL0834015.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSIAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLAFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36048..37352
                     /locus_tag="TU257_000997"
     CDS             36048..37352
                     /locus_tag="TU257_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0834016.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37353..38213
                     /locus_tag="TU257_000998"
     CDS             37353..38213
                     /locus_tag="TU257_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0834017.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38238..39068
                     /locus_tag="TU257_000999"
     CDS             38238..39068
                     /locus_tag="TU257_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL0834018.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
     gene            complement(39131..>39226)
                     /locus_tag="TU257_001000"
     CDS             complement(39131..>39226)
                     /locus_tag="TU257_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0834019.1"
                     /translation="ITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
BASE COUNT        10915 a         7400 c         9076 g        11835 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggcctta aaagcctaag gctagactag tcactggctg ggttagctgc
     7801 tgaattgata gtaaaaaaga ccagtcttag actgatctgt agggtgatta gatcgcccat
     7861 tctcctcctc ggaagattgg aatgacttct ccgtctttgg taatgccatc gatatccatt
     7921 tgttcagaac caatcataaa gtccgcgtgg gctgttgagc gatttaggcc agccgcttcc
     7981 caaatgtgct gctcaggcat tccaagtctt aggtcagttc ctggtgccct gtagtgaagg
     8041 ctgtcaaact gataatcatt gaggagcctt gccttttttt ctaaacgttc ctgatgttgg
     8101 tcccaggcct tgacaggatc tgtctcgtaa atgcgattca ttttgaaaat ggcatcccac
     8161 aaagcgtcca cctgctcttc ttcgcttgtc aggtttggaa aaaccatagc agcccattcg
     8221 ggaccggctg cagctgctag attccagctg actttgttgg cctgagtggc agcccgctgt
     8281 ttttcaagag caatagctgt tgcgcgtgtt gctccagcta gcctatcaga atcaatatca
     8341 gcaaagacgt ttggattggc agagcgaatg actaagcggc ttgctttttg atcaaggaga
     8401 taatgtgact gttcaacgac ataatctggt acctgcaaga gacggtcttc atcagcctta
     8461 agaagcttct cgcgtgtgat ctgatcgtca ttatagtcaa caagaacctc agctgcacca
     8521 gcctcatagg cttttttggt taatagccgc gcaagcttgt gttgctctac tgcaatagaa
     8581 atgagtagtg tgtgaccttt ttgaatgttg actccttttt tgataagaag gttagcgtat
     8641 ttttcaagat aatcgtcaaa atgtggcaaa accatagcag tctcctaata tgttaatgtt
     8701 gcaaaattta atgtatcata tttgcgacta tttcacaagg agctagcctg tttcataggc
     8761 taaatgtctc ctagaatgcc tatcgtaaaa ggctcagtgt tggttttctc tgatgagtta
     8821 aaaaacgatc ccttttttga tcagtttgcg ctgcccttgc taatagatat ttgcttaata
     8881 gcgacattcg tgttaagata taagaggaaa aaatcaatag atgaggtatt taacagtggc
     8941 atttggagaa aatggacctc gcaaaaaaac tgcctttgaa aagttgacaa cagttgttgt
     9001 gatcgtgatg gttcttgtga ctgtcggtgg acttattgcg ggtgccctgt cagtattgat
     9061 gtaagaaaac gctgaaaggc gtttttttag gataagagaa ggtttgagaa gaaaagtatg
     9121 agtatgtttt tagatactgc taaggtcagt gttcaggctg gtcgtggcgg tgatggtatg
     9181 gtggcctttc gtcgtgaaaa atatgtgcct aatggcggcc cttggggcgg tgatggtggc
     9241 aagggtggct ctgtcatttt caaggttgat gaaggtttgc gtaccctaat agactttcgc
     9301 tacaatcgta agttcaaggc caaatccggt gaaaaaggca tgactaaggg catgcatggt
     9361 cgtggctcag aggatttgat tatctcagtg ccacagggaa cgactgtgcg tgatgctgaa
     9421 accggtaagg ttctgacgga tctggttgag catggtcaag aatttgtcgt ggctaagggt
     9481 ggtcgtggcg gtcgtgggaa cattcgtttt gcaacgccgc gcaatccagc acctgagatt
     9541 gctgaaaatg gtgaaccagg agaggagcgc caattagagc tagagcttaa gattttggca
     9601 gatgtgggac tggttggttt tccgtcagtt ggtaaatcaa cgctactaag cgtggtctca
     9661 tcagccaagc ccaagattgg tgcttatcac tttaccacta ttgtgcctaa tctaggtatg
     9721 gttcgaacca aatctggtga gagctttgct atggcagatc ttccaggctt aatcaaggga
     9781 gctagccagg gtgtggggct tggcactcag tttttgcgcc atattgagcg tacacgtgtg
     9841 attctacatg ttattgatat gtcagcagct gaaggacgag acccttatga ggactatgtg
     9901 gcgattaata aggagttaga agcatataat cttcgtctta tggagcgtcc gcaaattatc
     9961 gtcgccaata aaatggatat gccagaggca aaggagcagt tgcagcgctt caaggaacag
    10021 ttagctgctc agtatgatga ctttgaagaa ctgccaataa ttttcccgat ttctagcttg
    10081 gcacatcaag gcttggatag cctattagaa gcaacagcag agctattagc aaaaactgat
    10141 gatttcttgt tgtatgatga ggctgatttg gctgaggacg aggcttatta tggctttgcg
    10201 gctgaggaaa aggcctttga gattagtcgt gctgatgatg cagcttgggt attgtctggt
    10261 gagaaattag agcgtctctt tgtgatgacc aatctggagc gcgacgaatc tatcatgaaa
    10321 tttgctcgtc agctacgtgg catgggtgtt gatgaagcgc ttcgtgagcg tggtgctaag
    10381 gacggcgaca ttgttcgcat tggcaagttt gagtttgaat ttgtagacta atgacaaata
    10441 ccaagcttag ctgttttttg tagcaagtga tgctgagtca tatctgaagt aggctgtttg
    10501 ctcaattcac agcaatgagg tcttggttga tgtgagctag ggaggttttt tatgggagat
    10561 aaaccaatat ccttcaagga taaggacggt aactttgttt cggcagcaga tgtctggaat
    10621 gctgaaaaat tagaagaatt atttaatctc ttaaatccca ataggcgttt gcgtttggaa
    10681 cgtgacaaat taaaaaagga tgaagcttaa gtgcacttcc tctcaatcgt tagatttagt
    10741 gtctaacttt tgagggtgca cttcaaggct tcgtcctttt ttgatgcttt ttttcttggt
    10801 gatgctgcaa atgtagccaa ttaaaaaagg tgtaaatgtc attaacaaga aaggctgcaa
    10861 aacaaatgac cactgcgtat tggctggtat ttgcttgagc agcatagagc cacaggagaa
    10921 ttaagaccaa atcattaaga gcataggcca aggcaaaata agggctacgt ttgtagctta
    10981 agtaggctgc tgaaaaagag gtggcaatag ataaggtaga aacaggcaga taggctgtct
    11041 taagataggc taagatagca tagaacaagc tggtaactag tatggtaaga accactaagc
    11101 gcagccggtc tgctgttgtc aagcgtgaga tggttacctg agatgtctgg tcttcaaatg
    11161 ggtggcttag ccaggtaaac agtgacaaaa tagccatcgg cagggtcatg aagagatagg
    11221 ttatcagctc cccgtaataa ctgtttaata gtgacagata ggcataaata agggagaaaa
    11281 taatggccaa gctctgtcca atcggatttg ccttggcact aaagattaaa gctgtcacac
    11341 cgattaagga agctatcagt gctaagggag cttgttctcc aaagaaaaag gcactgagga
    11401 gaatagccga aatggaggtt aaccaaagcg tccactcggt ttttgtaaaa tagtttaaat
    11461 aagccatatc cttattcaag cataggcctt tttatctgtc aatagggtgt cgaccttagg
    11521 gaaaaataag ctaatacctg ccatagtgca attggttgtg aggcactaat actagcagat
    11581 aatggtgtta actagaggca aatgagctaa gagtttcctt attggctgct gctaatactc
    11641 cttgttgact ggtttagaag aaaaggacta agagccttag cttggctttg tcagttagtt
    11701 tccttgatga taaggaaaaa ctagattttt taaagcgttt acagtgtcct tttttcttcc
    11761 tataataggg gtataagtga caaaaagaaa ggaaaaagca tatgaagcaa tcaaaacgcc
    11821 gttaccaatt tccagaaggt tttttgtggg gaagctcaac atctggccct caaagtgagg
    11881 ggactgtttc tggagatggg aagggaccta gcaattggga ctactggttt agtctggagc
    11941 cagataagtt tcatcatcag attggtccag aggtaacctc aaccttttac accaactaca
    12001 aaagcgatat tgctctttta aaagagaccg gtcacacagc ttttcggacc tctattcaat
    12061 ggtctcgact gattccagaa ggggttggtc aggttaatcc aaaagctgta gccttttacc
    12121 gagaggtatt tcaggaaatc atggctcagg acattaagct gattgttaac ctctatcatt
    12181 ttgatctgcc ttatgccttg caaggaaaga gaggctggga ggctaaggag acggtctggg
    12241 cttatgagac ctatgctaag acctgttttg agctttttgg tgatttggtg gatacatgga
    12301 ttacctttaa cgaacctatt gttccagtcg aatgcggtta tttggggcat taccactatc
    12361 cttgcaaggt agatgccaag gcagctgttc aagtggctta ccatacccag ttggctagct
    12421 cacttgctat caaggcctgc cacgagttgt atcctaagca taggattagt attgtgctta
    12481 atgtgactcc tgcctatcct agaagtgatc agccagaaga tgtcaaggca gcgagaatcg
    12541 cagagctttt ccagactaaa tccttcctag atccgtctgt cttaggagtg tacccagaag
    12601 agttagtagt tcttttagag gcagctgatt tattgcccca gtatagtgct gatgaattgg
    12661 ctattatcaa aaacaatcct gttgatttct tgggagttaa ttactatcaa cctttgcgtg
    12721 tgcaagcgcc tagcaaaaca agacaagatg gtgaaccaat cacgctagcc tcttattttg
    12781 aaccttatga tatgccaggc aaaaaggtta accctcatcg cggttgggaa atctatgagc
    12841 agggccttta cgacattgct cttaatttaa aagagcatta tggcaatatt gactggttag
    12901 taactgaaaa tggtatggga gtagaaggtg aagaagcctt tttagttgat ggtcagatcc
    12961 aagacgatta ccggattgcc tttatcgaag accatttgat tcaattgcac agggctttag
    13021 aagaaggcgc gaactgtaaa ggctacctcc tgtggacctt tattgattgc tggtcttggt
    13081 taaatgccta taaaaatcgt tatggcttgg tagccttgga tttagagact caaaaacgaa
    13141 cccttaaaaa atctggccac tggtttaaga ccctgagtca gacaaatggt tttgataaat
    13201 aggagcgtat gatggtcacc ttaggatttt ccctttaccc tgagcggcat ggttttgcta
    13261 agagtaaggc ttatattgat ttactgcact gctatggagc caagcgcttg tttatgagcc
    13321 tcttacagtt ggcgccaaat gatcccaaga cctttaagtt ttatgcggat ctgattgctt
    13381 atgccaattg cttgggcatt cgggtcattg cagacgttag ccctgctttt atcaagcagg
    13441 ctggttggtc agatcaggtt attgaagagg ctcatgcttt tggcttagca ggcttgcgtt
    13501 tagatgaggc cttgccttta gaggatattg ttaggctaac gaaaaactct tttgggctta
    13561 agattgaact caatatgagt actgacaaga gtttattgac agccttgcta aaggcagctc
    13621 ctgatcggag taacctcatt ggttgtcata atttttaccc gcacgccttt accggcctgt
    13681 cactggagca ttttaaggaa atgtcccatt tttaccacga gcatgggatt gcaacggctg
    13741 cttttatcac agcccaatca gcaaaggaag gcccttggcc gctgtcagag ggcttaccga
    13801 ctgttgaggc tcatcggcaa ttgccaattg acgtgcaggt ggaactgatg aaggcgacag
    13861 gaactattga tactgtcatt ttgtccaatc aattcatcac tgaagatgaa ctcgttcagt
    13921 gccgtcaagc cttggataga tcagtcatgt ctattaaggt caagcctctg gttgatttga
    13981 cggacataga ggagaagatt atctgttacc cacattgtta tcggggagat gtatcagatt
    14041 atgtgattcg ctcaaccatg ccgcgtgagg tatatgctca agaagcaatt gctccaagag
    14101 agcagcccaa gcaggttaag cgaggcagta ttatcattga taatgaccgt tacaacaggt
    14161 acaagggaga attgcaaatt gcactcaaag cctttaccct tagctcaaag gccaatgtgg
    14221 tcgccaacat taaagaggat tacctaagcc tattagacga gttgaagccc tggcaggagt
    14281 tttcattggt gattgagact gactagtctg gcttcacaat cgatacggaa aatgatggtc
    14341 acttttttca ggaaacattt gctaaactaa gagagtaaag aaagcgtttt ctaaaagacg
    14401 aaggaggaat gatgctatca aaaaaagaaa tggctatagt agcatttcta atcagccaaa
    14461 aagggcagtt tgtctctagt gctaccttgg ctaaggctat tggcatgagt gatcgcacag
    14521 tcagaaaata cctaaaggag ctgattagca gccttcctag taagggagcg cacatcattt
    14581 ccaagcaagg tcagggctac tgtttagaga ttgatcattc tatggcgttt gagatctttt
    14641 ggcaggaaag cttggcctct aaaaagcgct tggctgatgt gactcaggtg gaagaaacag
    14701 ttgatcggga gcattatttg ctaaataaat tcttctttga agagcccgtt tgggattttg
    14761 aagagctctg ccaagaattg tatattagtc ggacgaccct aaaccatgtt ttagcggtta
    14821 ttagagaccg tattaggcct tatcagctac agcttgatgt gagtcatcag cgcgttcagg
    14881 tgacaggtaa ggaagaggct attaggcatt ttatcatgga ttattttttt gctaccagct
    14941 ttgatgactc catgtacgcc atagtagaca atacctttct tgatcatatc aagtttgctg
    15001 atatcacaat aattgtttta gatgaatgtc gagatgccaa actaaagctt tctgattttg
    15061 tcatgcacaa tttggttttg cacattgccc taatggttca gcgtattcgg tctggctatc
    15121 cgttagcatt tttttccatt ccagcagcta ttcgccaatc agacgagtat caagtggctc
    15181 tacgtatttt atatcgagta gaagaagtga tgggcattcg ttttcctaaa gaagaagcta
    15241 actatattgc tttacacctc aaggttaagc attccgttga tggcagccca caggacaata
    15301 aggccgatga cttgctgaga agtcatttaa aagcaggtat tgtcaaggct agtcagctga
    15361 caggtatgtc tttggaggct gatagcagct tgcttcaagg cctattggcc catatgaagc
    15421 ctttagccac aaggcttgaa aatcatattc agctgaccaa tcccttaact gaggagatta
    15481 aaagcaaata cccagaggct tttgccctga ctaagcaagc ttttgagaat attcctgagc
    15541 ttcaggctta tgacctgtct gatgacgaat gggcttacat tagcttgcat atcatggcag
    15601 ctattgagcg ctattccaat cgtcacaaac tgagggtgct tgtggtttgt gccacaggct
    15661 atggcagtgc catgatgctg aaaaatcgct tggaaaagga atttgaaggt cgctttcaga
    15721 ttgtagatgt tatcagctac tatgaaataa cacaggaacg actgcaaacg gttgatgtga
    15781 ttatttcttc tatcagcctt gctaatgtca tgtttttaac gccagtcatt actgtcagtg
    15841 tctttttatc tgatcaagac atcaaagcca ttcgccaatt tatcggggag caggagggaa
    15901 taagaagaga agctgcgtcg tcatcgcaga tgagcttgga aaaagcagag cagattctaa
    15961 aaggtgtctt tagtcctaag cgttttcttt atgtgaaaga aaaactatca aagaaggcct
    16021 tgctgttaaa gatgattgct tgtcttgacg aagcaatgga tgaagccttt gttgaggcct
    16081 tttatcacca aatcgtgttg agggaaaatt atagctcaat tgtttttggt gaggtgcttg
    16141 cctttccaca cccggctaat cccatgacct attctgaaca ggtggtggtg gctgtctgtc
    16201 aagagcctat tgactgggac gagagtcatc gggctgttca ctttatcttt ttgttgtcac
    16261 cgtccaaggg acgtaacagc tatttaaaat atatctcacc gagcttggtg tcttttgtca
    16321 atcaagcaga gcttcagcag gctttattag aagaaccaag ctatgcacaa ttcatcacat
    16381 tatttacccc actcatcact gaataaaagg agaagtatta tgaaaaccat tatgttagtt
    16441 tgtaatgccg gcatgtcaac cagtatgctg gtgactaaaa tgcaaaaagc cgctcaagcg
    16501 cgtggcatcg aggttgagat ttgggcagtt cctgtgagcg aagctgacaa tgaggttgct
    16561 gctaaaacca ttgatgtcct catgttaggg ccgcaggtca aattcttact aaaggacttt
    16621 aagaccaaat ttgaaccggc aattaaggta gatgtcatta acatggctga ctatggcctc
    16681 atgaatggtg acaaggtgct tgaaacagcc ctaacaatga tggaggaaga ggtatgacac
    16741 aatcatcaaa cctagaggcc attatgggat taatcatgta tggcggtgag gccaagggca
    16801 aggctgtaga agctattcat gcagctagag atggtcaatt tgaaaaggct cagcacttgc
    16861 ttcaagaggc tacacattct ttaaatgttg cccatagatc acaaaccaat ttgctatctc
    16921 aggaagcagc tggagatcag gttgatttgt ctttattgct ggtgcatggt caggatcata
    16981 tgatgacagc cttagccttt attgatttgg ccaaggaatt ggtcgctgtt tatgacaaaa
    17041 tatcaagaat ccaaagaggt gagctatgat gatgattaca gcagaaggag atgtctctgt
    17101 cactcaatgc ttcaaggcta tactaagctc tctccaagag gattatcatg aaaacaccct
    17161 gagacggctg ccaccagctg aattaaaagc agggctaagc tacataaagc attatggcaa
    17221 aagcaaggag cataacgtta gagtgctgat cacagcctta gaagctccgc acttatatgc
    17281 tgcttgcttt agctctaatc atgggctaaa aacattaagc taccgcttag aagctctggg
    17341 agagaagcgt accaaaataa cctattgcta cgactatcag ccacttgatg tctttcaaaa
    17401 agccaatcag ctgatcattg ggaagctttt taagaagagc ttcaaacggc aatcacaagc
    17461 ccaattggca gcccttatcc aatatgctaa gcagctaagc taggggaaga tttgagtaca
    17521 gattatctgg ctgattatag ggcttatcat actaaaaaat agaaacagga gaaaattatg
    17581 tcacattttt cggataagtt tatggagatt tcaggaaaga tgggatccca gcggcatttg
    17641 gttgccattc gtgattcctt tatttcgcta atgcccatca cgatggcggg ctctgttgcc
    17701 gtcttgctga atgttttctt gcgtgatatt ccaaacaata tgggctggac tggttttgca
    17761 gcagccatgc agcccattat tgacatcaat ggttatgtgt attttgggac aattggtatc
    17821 atggcactct tttttgcctt tgcttttggg tatcatttag ctcttatgca caaggtgaat
    17881 cctttggctg gaggtttaat ctcctttgct tcctttgtcg ccacccttcc tcaaagctta
    17941 accatttcca caccacttga aggggcgtca gcaagtttat tagcaggctt aaaggatatg
    18001 ggactatcag tggtcactgc aaatggagcc cgagttttag aaacaagcca gtggggagca
    18061 attgccctca aatatgctgg agcaacaggt ctttttacag cattgatcat tggcttttta
    18121 tctagctttg tttatgcgac tttgaccaaa cgtaacctga ccatcaaatt gccagataat
    18181 gtgccacctg cggttaataa ggcttttgcg gctattattc cagggacagt cgcgatttat
    18241 gtgtcagcga tcgtagctta ccttattttt gccctcacag gctcgtctct aagtgatatg
    18301 atttcgacct atatccaatt gcctttgttg gggctgtctc aagggcttgg ctctgttatc
    18361 ctgttaacct tcttggttca attgctctgg ttctttggtt tgcatggtca caatgtctta
    18421 gcacccgtgc ttgatggtgt gtacttagtg gctctaacag aaaatacagc tgcctataat
    18481 accagtcaga gcgttgctaa tctgccttat ctctggacga gaggctcctt tgatgcctat
    18541 gcacaaatgg gtggttcagg tgttactctg gctctgatta ttgctatctt tattttctca
    18601 aaacgtgagg agcacaagac cattgccaaa ttatcagcac cgatgggcgt gtttaacatc
    18661 aatgagccaa ttacctttgg tatgcctatt gtcttgaacc caacctttgc tatcccatgg
    18721 ctaatcgtac caccaatttg tgctagcatt gcttatgctg ccacagcaat aggcttgatc
    18781 cctcccgttt tcttgccagt tccttggatt acgccagttg gactttacgc ttacttggct
    18841 actggaggta gtgttatggc aggtctggtt tccttgttta acctctttgt tgcctttctt
    18901 atctgggcac catttgtcat gtcagctaat aaagaaaaag cgagtgacct ttcatgacag
    18961 caaaaaacgg agcaagcttt ttaatggcta taggattttt ccttattgcc attagtccaa
    19021 tggttggcaa caaataccta catatcgtga caggactagc ttttgttggc ttagggtatt
    19081 atctcactaa gcgcaagcgt ccttagtcaa tgcgagcagc tagcccctat gaaaagacaa
    19141 acctaagggc tagccttgat tttctatctt ggttatcgca tttaaaagca agcaaaaaag
    19201 caagggtaga tgcttacctt tgcttttttt attttttgac ctttaataga atatcttgct
    19261 acttaaacat ttaagacctt atctaaaaat tcaattaagc gtgggtgctt agggtgatca
    19321 aagatttcct ctggagtacc gtcctctagg aattggccgc cgtctgtaaa gatcacacga
    19381 ttagccactt gacgagcaaa gcccatttca tgtgtcacaa tcagcatggt catgccctgc
    19441 tctgctaggt ctttcataac gtttaagacg tctccaacca tctcagggtc aagagcagag
    19501 gtaggctcat caaagagcat gatatcaggg ttcatggcaa gacttcttgc aattgcaaca
    19561 cgctgctttt gaccacctga tagacttcct gggaaagcgt cagccttatc agctagaccg
    19621 accttctcta gaagagcaag tcccttttcc ttagccgcct cctttgagac ctttccaagc
    19681 tcaactggtg caaaggtaat gttatcaagg actgtcatat gtggaaagag attgaagtgc
    19741 tgaaacacca tgccgatatt ttcacgagcc ttatcaatat tggtattagg atctgaaagt
    19801 tcaaagccat caaccacaac cttaccacta gtaatggatt caaggagatt gagggtgcgc
    19861 aggaaggttg attttccaga gccagatggc ccgataatac aaacgacatc accctcgtaa
    19921 aatttagcat taatgccttt taagacctca ttttgcccat aggatttgtg taaatcttga
    19981 acatcaattt ttaattctgc cattagttaa gcctcttttc taaacgtttt gcaagccttg
    20041 ttaagagtgt aatcataatc aagtagataa ctgctaggat agcatacatg cggaaggatt
    20101 gatagtttct agcgataatg attttccctg tttggaagag ctccactaaa ccgatcgctg
    20161 agactatggt cgtatccttc aaggaaatga caaactgatt gatgaagttt ggcagcatta
    20221 gcttaatggc ctgaggaagg ataatccttc gcattgttgt gtgatatgac aagcccaagc
    20281 tgcgactagc ctccatttga cctgccggca cagcctcgat acccccacga acaatttcgg
    20341 caatataggc tccaccattt agcgaaagtg caatagtagc agctacaaaa tcgttaatcg
    20401 gtgattgatg cccagtcatg ctttcaatga ggtttggcac tccccagaag ataaaggcag
    20461 caacaatcat caaggggata ccacgcacca catcaacaaa gatagtagaa gccatgcgca
    20521 ggttctttga tggggataca gccatcattc caaaaacaat accaataacc aaagcaatgg
    20581 caaaggagat gagtgtcaga ccaagggttg ttccaagccc agccaataat tgcttgtagt
    20641 tattagctaa aagtccataa atagttgact catcggctgt tttgacagat gcctctgaat
    20701 caaggtatct gctgatgatg gcgtcgtatt ttcctgatgc tttaagagca gccaaaccgt
    20761 tgttaaacat ttcgatgagc tcagggttgg ctcctttttt aacagcaaaa ccatactcac
    20821 cagaaggctc tcccttgata ggaatatcaa gcttgtggcc tcgctgaata gcgtacctta
    20881 aaatagcttc atcatccata agcccgtcaa tagaaccaga atttaagcta tcgtacattg
    20941 aggaggcctc atcaaaggct tttagacggt aaccataaat atccttgttg ctttcaagga
    21001 aatcatagga ggctgttcct tttttggcac cgactatttt acccttgagg tccttgtatg
    21061 atttgataga gcttccggat ttgaccccaa ggcgaatgtt tgatgtgtag taggaatctg
    21121 aaaaatcaaa aatctcacga cgtgcaggtg tgatagacat acctgcaata acagcgtcag
    21181 cctgaccagc ttgaacagca tttaaagcag cgtcaaagcc aggattgctg atctcaatgg
    21241 taaagccttg ctgcttagca attgccttga tgaggtccat atcaataccg acatattctc
    21301 cgctgccaat ttgaaattca aagggagcaa aggaggagtc agccacgatt ttataaaccg
    21361 gctttaaagg agtggcctta gcagaggcat cgccagtagc cttgcctgct gtgaccttgt
    21421 cattgctgcc aagccatttt gtcatgatag cttgataggt tccatcagcc ttcatagcgc
    21481 ctaaggcttc attgaagtcg tcaatgagat aatcatagcc gctgcctttt ttgacagcaa
    21541 agccaaagct tccaatagcc tctcccttca tgttgatcgc aagatcctgc ttttggttaa
    21601 tggcatattg aatgacaggc tcgtcgtcca taacagcgtc aatagagcct gttgcaagac
    21661 tgttgtacat caggtcacct gtgtcaaatg ttttaacagt ataaccatac gattttttgt
    21721 atttatctaa gaaggcttga gcagctgttc catttttaac accgactgtt tttcctttta
    21781 gctcgctata tttcttaata gggttagcct ttcttgtagc aataacaatt tttgtatcgt
    21841 aatagggatc tgaaaaatgg aagacctttt gacgagcagc agtgatggtg gtgcctgcca
    21901 taagggcgtc agcttgacca gactgaatgg cattgacagc agcatcaaag ccagggaatg
    21961 tcatattgat attccaaccc tttcgctttg ctacttcatt gatgatgtca acatcaatcc
    22021 ccttatacac ctgatctgaa tccttgaatt caaacggtgc ataagcagta tcagaaacaa
    22081 tatcaattgt ctctgcactt gcaatcccag cagtcatcaa aacaactgac agcattgcaa
    22141 gcatccatgc ttttaatgtg tttttcatac tagtctcctt aataaaaata aaaaatatgc
    22201 ctaattatag cagatttttt tcaaacaagc aaatcatctc ttctttttat gtcataaaac
    22261 ctaacataaa caactaaaat agtcaaaaag ctttgataga gtctttaagt ccttaactat
    22321 gttacaatag ataagagata agatattgag gaccaataaa tgattgataa acgtgatttt
    22381 aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca ggcgattgag
    22441 accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg agcaacagga
    22501 acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc aacgttagtg
    22561 gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga gttctttcct
    22621 gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga ggcctatgtt
    22681 ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat tgacaagctg
    22741 cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt ggcttcggtt
    22801 tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt tagcctgcgt
    22861 cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat tcagtttgaa
    22921 cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt ggttgaagta
    22981 tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga tgagattgat
    23041 cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga tcatttagtg
    23101 ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc tattagcaag
    23161 attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa attgctagag
    23221 gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga aatgggctac
    23281 accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg agagcctcct
    23341 tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga gagtcacatg
    23401 accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca aatgcttgtg
    23461 gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg ggaggagttt
    23521 gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta cgagatggag
    23581 cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga tccggaggtt
    23641 gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa cctgagggtt
    23701 gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga ggatttgacc
    23761 gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat caagacatta
    23821 gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt gattggtatc
    23881 aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat tcttgatgcg
    23941 gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg tcgagctgcc
    24001 agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc catgcagcgc
    24061 gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga agagcatggg
    24121 attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc cagagcagtt
    24181 gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc tgaaagacaa
    24241 gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct ggattttgaa
    24301 ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta agacctgata
    24361 agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt cctttaggtc
    24421 tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat ctacgcaaga
    24481 gctagtgcag ccactagctt cagactactt taatgattta atgaaagatt gattttgata
    24541 agacaattct gatataatgt aaagtagttg gcaaaaatag aaacattaaa taaattttct
    24601 ttttaataat ttaactttta ccttgtcaac aaggctattt tcggatagaa tttcttagta
    24661 cattatttca ctaatacaag aaggtaagta tgttaaaaaa caagtcaaga ctgcgagcta
    24721 ttttcgtttt tgttgggaag atagcgttgt tttacgtgat tttgatgctg ctcgtttatt
    24781 tttttggtta cctagggcat ggtcaaagta attttattta taatgaattt taggagattg
    24841 tctgatggtt aacgatatga ttgaaacaat tgagtatttt gcacaagcac aaccggattt
    24901 tccagtttat gattgcttgg gagagcgccg tagctatggg cagctaaagg aggactcaga
    24961 tagtattgca gcccttattg agagcttaaa gctaggtgaa aaatcacctg ttttagtttt
    25021 tggggctcaa agctatgaca tgctggcttc ctttgtcgcc ttgacaaaga caggtcatgc
    25081 ttacattcct gttgatgttc attcggcgcc agagcgtgtc ttgtctatta ttgagattgc
    25141 tcagccaagt cttatcattg ctattgagga gctgccggtt agtattgatg cgattagggt
    25201 ggttagctta gcagagatag aggcagctaa agcagccaag gcagccttta ccatgaccag
    25261 tcctgtcaag ggagatgaca attattatat tatcttcacc tctggaacga caggacagcc
    25321 aaagggagtg caaatttcgc atgccaatct tttaagcttt accaattgga tgattgagga
    25381 tgctgagttt gctattcctg agagaccaca gatgctggct cagcctcctt attcctttga
    25441 tttgtcggtg atgtattggg cgccgacctt agctttaggt gggacattgt ttgctttacc
    25501 caaggaaatg gtttcagatt ttaagcgctt gtttagcaca attgcggagc tgccgatagg
    25561 gatttggacc tcaacaccgt cctttgccga catggcaatg cttaatgatg atttttgtca
    25621 ggagaagatg ccaaggctga cccactttta ttttgatggg gaggagctga cagtatcaac
    25681 tgcaagaaag ctatttgaac gctttccaga cgcacgcatt atcaatgcct atggtccaac
    25741 agaggcaacg gtggcgttat cagcgatttc aatcactaaa gatatgatag agacttacac
    25801 acgcttgccg ataggctatc caaagccgga ttcgcctact tatatcattg atgaagctgg
    25861 caatgctctg gagccggggc aacagggaga gattattgta acgggtccag cagtttctaa
    25921 gggttatctc aacaatcctg aaaagacagc tgaagccttc tttaccttta atggcatgcc
    25981 tgcttatcat acgggagatt taggatcatt tactgaggac aatgtgttac tttatggtgg
    26041 acgattagac tttcaaatca aatatgcagg ttaccgcatc gaattagaag atgtgtcgca
    26101 gcagctaaac caatcaccgc tggttgaatc agcagtagca gtaccaaggt ataacaaaga
    26161 gcataaggtc caaaatctct tagcttatgt tgtcttgaag gacggggtga gggagcaatt
    26221 tgcgagagat ttggatatta ccaaagccat taaagcctct gttaaggatc atatgatggc
    26281 ctatatgatg ccgtctaagt ttatttatcg tgaaaagctc ccattgacac caaatggcaa
    26341 aatcgatatc aaattcttga ttaacgaggt taatcatcaa tgacgacctt gtttcatcac
    26401 ataccttata tggagcctta tggcaatccg atttattttg tctacctcat cattgctttt
    26461 cttccagtta ttattgggat ctttaagcaa aggcgttttt cgacgtatga aagctttgtc
    26521 agcctgatct ttattttgct catgtttggt ggagagcact atcagcaatt gcttgccttt
    26581 ttagcctatc taatttggca aaccatcagt gttttggctt acaagcacta tcgtcaaaag
    26641 gcaaatgcag cgtgggtttt ctatcttagc attttagcca gtctatttcc tttgatttgt
    26701 gtgaaggtaa gcctcagtct aacgaggtct ttctttagct tcttaggtat ttcctattta
    26761 actttcaaaa gcgttgggat gatcattgaa atgcgtgatg gggttttgac agattttagt
    26821 ctaaaggatt ttctacgctt tatgattttc tttccgactt tttcaagcgg gccgattgat
    26881 cgcttcagaa ggtttcaaga ggcttacacc aagcttccta gtcgtgatgt ttaccttgat
    26941 atgctcaata aggctgtcat gtatctcatg ctgggctttc tgtacaagca tattatctct
    27001 tattgcttgg gtgggctgct attgcccctt gctgaaaata aggctctgac tgtaggtggc
    27061 tactttaata aagagacgat ctatgtcatg tacctttatg ggcttaatct cttttttgat
    27121 tttgctggct actcgatgtt tgcgattggg ttgtcttatt tactggggat taagacacct
    27181 gaaaatttca ataagccctt cttatcacca aatttaaaag agttttggaa cagatggcat
    27241 atgagcctat cattttggtt tagggatttt gtttttatgc gattggtcca tctattgatc
    27301 aagcacaaga cctttaagaa tcgaaatgtg acttcgggct ttgcttacct gatcaacatg
    27361 ctggtgatgg gactttggca tggcttgacg tggtattata ttgcttacgg tctgtttcat
    27421 ggtattggct tgattgtaaa cgacgcttgg cttcgtaaga aaaaggaaat caatcgtcgt
    27481 cggaaaaagc aagggcttaa gcctttgttt gagggtaagg tatttcatgc tttatcaatc
    27541 gtggtcactt tccacgttgt cttgttctca cttctgttat tctcaggctt cttaaatgag
    27601 ctttggttta gcagaccgtt acgttaaaaa aggagagtat aaaaatgtct actaaagaaa
    27661 ctgtaattga cttatttgat cgcttgttta tggaagacgt atcagatatg atggacgagg
    27721 atttgtttga tgctggcgtt cttgatagcc taggaacggt tgagctgatt gtagagatcg
    27781 aatctatctt taacattaag gtgccaattt cagagtttgg acgtgaggac tggaacactg
    27841 ccaataaaat tattcagggc atagaggaat tgcagcatgc ttaaacggct ttggttaatc
    27901 ctaggtcctc taatcatcgc ttttggcttg gtttgtctta ccatattcag ctttcctact
    27961 aagcttagct attcattgcg ccaggaaaag tcaaatgcag tggcaatcaa tgatagctcc
    28021 tttaaaaacg gcttgattaa aaggcaggcc ttgtcagatc ctaactactg ttttgttccg
    28081 ttttttggct ctagcgaatg gagtcgcatg gatagcatgc acccatcagt gcttgcagaa
    28141 cgctacaagc gctcctacag accgttttta attgggaaaa gaggctctgc ttccttatca
    28201 caatattacg gcatgcagca gatttcacag gaaataactg gaaaaaaggc agtctttgtc
    28261 gtgtccccac aatggtttac cccccaaggc attgatcctg gtgcggttca attgtatcta
    28321 tctaatagtc aggtgattga tttcctctta aaagcaaagg ctagtcataa ggaatcacaa
    28381 tttgccgcta aaagaatgct ggacattaat ccgggagttg ctaaatcaga gcttttaagg
    28441 aaaattagtc aaggcaaggc cttgagtaga tgggacattc gtctgctcaa atggcagcag
    28501 gagctgtcct taagagagga gtccttgttt agcttccttg gtcgttcaac aaactatgag
    28561 gataggattt tgcctcgtgt taaagggttg cctaaaacct tttcttatga gcgcttgagc
    28621 gagctagcag ccagacgggc taaggaagga acttcaaata atcgctttgg catcaaaaat
    28681 gctttttatt ctaagcgaat tgcaccgcaa tttcctcttt ataagaattt tcagtgccgt
    28741 aataattaca ctgtgtcacc tgagtacaat gattttcagc tggtattgtc agaatttgca
    28801 aaacgtaaaa cagaggtgct tttcgttatt acacctgtta atcaagcgtg ggcaaattat
    28861 acaggcttaa accagaggag gtatcaaaag gctgtcagaa aaataaagca tcagttaacc
    28921 tcgcagggct ttactcgcat tgctgatttt tccagaaatg gcggagacaa gtattttatg
    28981 gaggatacca ttcaccttgg ctggaatggc tggctagcct ttgacaagga ggttgttcct
    29041 ttcttagagg atcaaacacc accatctgaa taccaactgg atccttactt cctatcaaag
    29101 gactgggcag atagaacagc aggattttag ggtcaataga ccattagaaa atgaggatta
    29161 gaattgttaa tgagtatcat cgtcatattg cttattttag ccattgctgt tttagtgatt
    29221 gagtatggtc aaaagcggtc cttttctagc tggctgcttg aaaagatgtt tgattatcgt
    29281 aagtataagc tctctaaaaa ggctgatgac tatgaaggaa ttgagacgca aagacgtcgt
    29341 cgcattccct accacttgga taatccagag gcggtattgg ggattcccac cacagaatat
    29401 acgattgatg gcatgcaggt ttttgtgatc aatgaccaag attctcagga tcagccagtg
    29461 atttactatc tttatggtag tgtctatttg cgtcgacctg agacatttca ctttaaaacc
    29521 attaagcatt tgatccattt aaccaatgcc aagctggtgt tcccaaattt tgagaaggcg
    29581 ccttatgtca cctataagga gatttaccca aagcttgcta aaacttatca ggagctttgt
    29641 ctagccaatg gcgctgccaa ggttagcatt attggtgact cctcaggtgg tggcatggcc
    29701 ttagccttgg cgcaatacct aagagatacc caaactgcac cacagccaaa gcaattaatc
    29761 ctgttatctc cttggttaga tgttagcttt gctaatcagg attataagca ttttgaagca
    29821 gtagaggctt atttagatgc taggcggctt cgagacattg gtgaattgtg ggcaggcagt
    29881 ccagaagaaa tgcggtctcc gtatgtcagc ccattatatg gcgattatca tgacctgcca
    29941 aagattgtca cttttgtcgg gacaaaagag attttttacc cagatattat gaccctgcat
    30001 gagcgcttga tggagcaagg gcacttaaat cagctcgtta ttgctgagca gatgattcat
    30061 gcttatgcga tcttcccgat acgagaggca aggcaggcgc gcaagcagat tgccgagctg
    30121 attttaaaga aggagtgatt gttgctatag gagtcagtta gccttgcttg tctgatgagg
    30181 cttgggcttg agatttctag agaagcttta aggcctttac ttgggctgtt aatgctcatt
    30241 aaagaggatt ataggcttta tactagggct taggattgct gttttgctat tcaataatat
    30301 tagtttagac ttgattgagg aaaggctagt tttagttatg gtcctcaatc tttttttgat
    30361 ggtaaacatg tcaagacagt ttacttgcta gggtaataat cctgtgctca tttcatgagt
    30421 ggctattttt atcctaagct tggtggtgga aaaatcagat taaaaaatat gaaatttgct
    30481 attgacagct gtaagcgatt gcattataat aaacttaact taaacgttta agttaagttg
    30541 aataagctga tttgatcatg cactgcctaa atgcaatcaa taatctcaaa gcatttggtg
    30601 tagtctagta atcaatgagg cagtttatta cggttataca atatttattt agttcatccc
    30661 tttaggaggt aaatagctat ggcgtgggat tggaaaaaag caggtgttgt tggagtagtg
    30721 tcattggctt cgatcatggt attaagtgct tgtagcggag gacatcaaaa agaggctaag
    30781 caaaaagacg acaataccat tgtagtttca gttgatgagg gctatgcaga ctacatcaaa
    30841 gagattaaga cagcctttga aaaggacaat aaggtcaagg tcaaggtcaa aaaggaaggt
    30901 atgattgata cgctagataa gctatctact gatggaccga caggtgcttc accagatgtc
    30961 tttttagcac catatgaccg ggttggtggg cttggctctg aagggcaaat tgctgaggtg
    31021 agcttaggca atgctgacca gtttgatgac actgttaaaa agctagtcac cataaatgga
    31081 aaggtttatg gggcaccaga tgttattgag accttagtga tgtattataa caaggatttg
    31141 gtatcagagg ctccgaaaac ctttactgac attgaagagc taaataagga tcctaagttt
    31201 gcctttgctt ctgaagacgg taagtctgta ggctttcttg ctaagtggac agacttctat
    31261 tatggctatg gcttgattgc aggctatggg gcttatgtat ttggagataa gggaactgat
    31321 ccaaaggatt taggtattgg taatgctggt gccattgaag gcttagacta tgctaagaaa
    31381 tggtatagcg tatggcctca aggcatgcag gatactcaaa aggctggaga ttttattaca
    31441 gagcaattca cctctaaaaa ggctggtgtg attattgatg gaccttgggc tgctgcctca
    31501 tttaaggagg ctggtgtaaa ctttggagtg gcacaaattc caagcttacc taatggcggt
    31561 agctatcaag cctttggtgg tggtaaagca tgggtgattt caaattattc taagaataaa
    31621 aagctggcac agcaattcct tgattatgtg acaaatgaga aaaaccaaaa agccttttat
    31681 gataagacac aagagatccc tgccaatcta gctgctcgca gctatgctgc agaacaagga
    31741 aatgaattga caaaggcggt tattgggcaa ttctcaaatg ctcagccaat gccaaatatt
    31801 ccagaaatgg cagaagtttg gggaccaggt gcgaacatgt tctttgaggt agcagcaggc
    31861 aagaagactc ctgccaaggc tgctaaggaa gcagctaaaa ccattcaaga ggctattgca
    31921 caaaaataca ctgaataaca taaaaaggga ggctgggata aaggtatcct agtctccatc
    31981 ttgttaccta tagtatcaga gtgggcgatg aggagataat aataaaaagt agtagtgact
    32041 agcttgtctt gtttcccatc ttgtcctaat aagagtatct gataagactg atgaacctag
    32101 ggaggaaaaa atgaacacag ccggaatact gcatattcca gattctagat attgctttgc
    32161 cttatcaaca aaggagcttg tgattcggtt gagggttgca aaggaggata acgatatagc
    32221 ggtgacgctg gtttatggac ctaagtatca ttatcatgag tatcaaaaag aactggcgat
    32281 gtatgctgct tataccgatc atacccatac ctattatgaa atcaccttaa gtcttgatga
    32341 tgttagattg gcctatattt ttaagcttga gcaatctggt cacacctatt actttagtga
    32401 ggatggcttg accacaagct atgatttttc aaatggcttt tacaactttt ttcaaatgcc
    32461 ttatattaat gctgtagacg ttcatcagac tgtcccttgg gtgcacaatg ctgtttttta
    32521 tcagatcttt gttgatcgct ttcatcgtgg tgactttgaa aaggacgata gctatattaa
    32581 tatggcttgg ctggataggc caactcctaa tagctttgcc ggaggggatt tgaaggggat
    32641 tacagataag ctggaatacc ttgaggatct tggtattaat gtcatttact tgacaccgat
    32701 tttcaaatcc atcagtaatc acaaatatga tattagtgac tactatgcta ttgacccgat
    32761 gtttgggaca tcgcttgatc tccagcaact aataaacgag gcccaccaaa gagggattag
    32821 aattatttta gatgctgttt tcaatcatgc tagcagtgat tgcgagccat ttcaggacgt
    32881 tttggcacat ggtagtgctt cttcattttt tgattggttt atgattcaag gagatcatcc
    32941 ttctgtagag ctagctaatt acgaaacctt cgctgattgt cactacatgc ctaagtggaa
    33001 tacctcgcat caggctgttc aggattattt gattgagatt ggtctttatt ggatcacaga
    33061 gtatcatatt gatggctggc gattagatgt ttctgatgag gtatcgcatg atttttggag
    33121 acgctttcga aaggctgtta aggcagtcaa atcagatgcg atacttattg gagagaattg
    33181 gcatgatgct tatccctacc ttcaaggaga ccagtatgat ggtattatga attacgcctt
    33241 taccaaggct tgtctcgatt attttgcatt tgatgcgatt agctcacagg aaatggctga
    33301 aagattgtcg catattttaa tgagaaatac ttggcaggtc aaccagatga atctgaattt
    33361 actggattcc catgatacgc atcgcttctt gactcaggtg aatggctcta aggacaaatt
    33421 attggctggc ttagcccttt tagttacctt tatgggcata ccatgtattt actatggaac
    33481 agagcttgcg atggagggag gttatgatcc tgactctaga cgtagcttta attgggacag
    33541 cagcacttgg gatatgagct tttggaatca ggttaaggac attatcagcc tgcgtcgtca
    33601 tgcggttatc caatttggaa gcatttcgat aacctcccat gatgactgcc tttgcgtaaa
    33661 gcgtgaatta aacggtcaat cgataagatt gctggttaat aatggcgtta agccatatcc
    33721 tattgagaaa ggaggttctg tgcttgtttc taatggtgta gataaagaga catttgagct
    33781 actccagaac gggtttgttg ttagctatta atatggcgtt ttatcaaagg aggttaagga
    33841 tgaagcgtat tactttaaca tgtcgtaaag cattaacagt agctatggca gcggttacct
    33901 tagcaatgtc aactaacagt gtctttgcta ttgaaaatac tgcggtgtct aataaggctg
    33961 atttttctac tgacacgatt tatcaaattg tcaccgatcg ttttcatgat ggtaatgctg
    34021 ctaataatgg aaatacagat gtatttgata aaaatgatcc taaaaaatat catgggggtg
    34081 attgggcagg tatcattaag aaactagaag atggctactt aaccaattta ggggtatcag
    34141 ctatctggat ttcatcacca gttgaaaaca ttgataccat tgacccttca aatggcagtg
    34201 cagcctatca tggctactgg gcaaaggatt ttttcaaagc aaacagtcac tttggaacaa
    34261 tggaggattt taaaaagctc attcaggtgg cacatggcaa aaacattaaa gtagttattg
    34321 attttgctcc taatcatacc tcaatagcag aatataatgg cttaaccttc cctgaggacg
    34381 gtgctttata taaggacggc cagctggttg gtaaattcag tcatgatgat caaaagattt
    34441 tcaatcatga atcatggact gatttttcaa cttatgaaaa tagcatttat cattccatgt
    34501 atggcttggc agacttgaac aatctgaatc caacagttga cgattatctc aaagaggcta
    34561 ttgataaatg gttagaaatg ggcattgatg gtattcgtgt agatgcggtc aagcatatgt
    34621 cacaaggctg gcaaaaaaat tggttgagtc atatctatga gaagcataat gtattcgcct
    34681 ttggggaatg gtttgctgac ggttctttta atgatccatt gatgactaaa tttgctgata
    34741 ctagcggcat gagcctgctt gattttaggt ttgctaattc tgttaggcgc ctgtattctg
    34801 atttatcagc gaaaatgcaa gatttttaca atatgattgt agctacggaa aaagagtaca
    34861 aggaagtttc agatcaagtg actttcattg ataaccatga tatgacccgc tttgctactc
    34921 tagtcaatca taatcagaca gctgttaatc aagcctatgc tttactgcta acatcgcgtg
    34981 gtgttccgaa tctttattat ggttcagagc agtatgctac aggtgctaac gaccctgaaa
    35041 atcgtggtga tatgccaacc tttgataaga attccactgc ttatcaggtg attagcaaac
    35101 tagcaccact gcgtaagaaa aatcaagccc tggcttatgg tacaacacag cagcgctgga
    35161 ttaatgatca ggtcttggcc tttgaaagaa aatttggaaa tgacgttgct ttagtggctg
    35221 ttaataagga tcaaacaaat ggctacacaa ttagtggcgc taaaacggct ttaccagctg
    35281 gtaagtatgc tgatgaatta ggtggcttac tgggcggaaa ggaattaacg gtatcagctg
    35341 atggtaatgt tgaggcattt gagttaggtg cgggtcaggt tgcagtttgg acctttaaag
    35401 ggcaacatga gacaccgcag ataggagacg tagacgcttc gtttggcgtt gcaggaaata
    35461 ctgtctctat ttcagggcaa ggatttggta gtgctcaagg tcagcttcat tttggtgata
    35521 gcaaagcaga tattgtgtca tgggacgata ccttgattca atttaagata cctgctgtag
    35581 ctgctgggaa ccatgatatt aaggtgacca catctacagg acaaagcagt agcccttaca
    35641 aagcctttga agtgttaaca gataagcaaa ttccagtaag attggtggtc aataatttca
    35701 acactgtatt aggtgagcag ctttatatcg ttggtgatgt ggttgagctt ggggcaaatg
    35761 ataatcataa agctttaggg cctattttta atgcaacaca gtcaattgcg cagtacccaa
    35821 attggttcta tgatgtcaat ctgcctatta acaaaaccat taactgtcat cttgtaaaga
    35881 aggatagttc tggtaaagta ttgtggacta gtccagaaac ctataccatt aaaactgata
    35941 gcaaggctca aaccatttca ttgaaaaaat agttgcgtta tctgtgatgt tatttaatac
    36001 tctatgaagg aggagaacca taaaagggtg atagagagga atgacaaatg cttaagaatg
    36061 aaaaaatgaa gaatccacaa aaagccatgt ggctttcaat aatccctggt ctggggcaac
    36121 tctacaatac tcaaaaggta aaaggcttta ttttgcttct tgtgttttta ggtgagctgc
    36181 tagaggcttt ctttgttggt attccggctc ttgctggctt gtacagcctt ggtagtgtac
    36241 caatggagga tcattcccta ttcttattga ttaagggagc tatgcagctt atcctatttg
    36301 ccttgttttt gatctttcat ttggctgcta tgcgagatgc tagactagtg gcaagggaga
    36361 tcaatgcagg ccatagcatt tcattaacct taaaggagat ggtacaatcc atctatgaaa
    36421 agggctttcc ttatttgctg attattccag cctacttggc catggccttt gccattgttt
    36481 ttccggtgct tgttacttta ttaattgcat ttacaaacta tgattttagg catattcctc
    36541 cctataaatt attagattgg gttggcatta agaattttaa aagcatttta gagcttagca
    36601 cctttaagtc agcctttggc tctgtgctgt catggacctt gatttggacc ttggcggcaa
    36661 cgagtctcca gattgtgata ggaatagcga ctgctattat tgccaaccag tcctttgtga
    36721 agtgcaggcg catttttggg gtgattttct tgctgccttg gggggtgcct gcttttatct
    36781 cgatcatgag ctttggtaat ttctttaatg attctatcgg tgctatgaat gttcaggtct
    36841 taccattttt agaaaagttt gtgccatttg cagattttgg gattatccca tggaagacag
    36901 atcctttttg gacaaaggtt gcggtgatta tggttcaggg ctggctgggc tttccttata
    36961 tttatatttt ggtgtctggt attttacaat caattcctgc tgatttgtat gaggcagcaa
    37021 cggttgatgg tgcaacagcc ctgcagaagt ttcgccaaat taccttgcca atgatctttg
    37081 ctgtcgcagc cccgacctta atctcgcagt atacctttaa ttttaataac ttctccatta
    37141 tttatctctt taataatgga ggtcctggta cagttggcgg tggcgcaggg tcgacagata
    37201 ttttgatttc ttggatttac aagctgacca cacaaacgtc accacagttt tccattgctt
    37261 cagcggtgac cttaatcatt tccttgattg ttatttctgt atcattgata acctttaaaa
    37321 aattcaaagc ctttgacatg gaggatcgct aaatgggtag gaattatttg ccacagtcag
    37381 tgaagaagaa gcgcttgtta gctcagctgt tgacttacag ctatttgcta atcctgtcga
    37441 tcatcatctt atttccaatc ttggtgaccg ttagctcagc ctttaggcca ggaaatacaa
    37501 ctgcctttag ctttcatatt gatgggcctt ggaccttatc aaactttgag acactctttc
    37561 aggacaccta ttacttaaga tggtactgga acacgttagt tgtcgccttt ttcacgatgc
    37621 tgatccaggt gacagtcatt acgctgacag gctatgctta cagccgttat cacttttttg
    37681 ggcgtcaaaa gagtttggtc tttttcttag tggttcagat ggttccgaca atggctgcct
    37741 taacagctta ttttgtgatg gcttggttgt ttaatgctct gaatcactat tggttcctca
    37801 ttctgattta tgttggagga ggcattccga tgaatgcttg gttgatgaag gggtattttg
    37861 atactgtgcc ttatgattta gatgagtcag ctaagctaga tggctctggt cactttagga
    37921 ccttctacca aattgtattt cctctggttc gtcctatggt tgctgttcag gccctatggg
    37981 cctttatggg gccatttggt gactttatgc ttgctaagtt tctcttgcgt gaacaggagc
    38041 attacaccgt agcggtaggt cttcagtcat tcatcactaa cgacgctagg gatcctaagg
    38101 tcacattgtt tgcagccggg gccattttaa ttgcagtgcc aatttcagtg ctattcttct
    38161 ttttacagaa gcattttgtt tcaggcttaa ccaatggtgg aacaaagggt taatttatct
    38221 ttcaaggagc ctttatcatg actaatgatc gatttcctat ttcttacaca accattattt
    38281 tttctcctaa aatgatattt gctcgttgca gtgccttttt gtggtggcag aatgtgattt
    38341 tagtgatctt tctaaatgct ctggtgttaa tgccgatcac gctgcattat gcaagcttga
    38401 agagctatcc cttagagcac atagttagta atggtttaga ctccttgaca gaaaaaacct
    38461 atcatgcctt gacacaaggc actatttggc atgatcgcta tgatggaaaa acagtcctta
    38521 tagaggatac tgatgctgtt gttgctgtat tgccaacacc agaaatagta gaagagctaa
    38581 agaaagatca aagaagccag ctgatattaa cagaaacctc atggatttta agctttcctg
    38641 atggtcaaag gctaactgct aaggttaaag gcaacaagga aaggctaacg cgcttaacct
    38701 ctctagaggc tgtcaaggcc tttgttaatc agcaatggta caatagcaat cgtgccgctg
    38761 tgcttgcctt tttgctgcta gtggctagca gtgtggtcta tctaggagcc ggtttagtga
    38821 tcggaattgg ctcgttatca ctgttattaa caagatctgc tagattattt tcactcaaga
    38881 gctactcaga atgcttgggt ttgctagtga attgctttgg acttcctacg cttttagcag
    38941 tgcttataag tttttgggtg cacaatccta ttgttatcat gaatagtcag gtctttggca
    39001 cactgctcat gctggttcta gtcttttaca aaactcagtt tagagatgag gagcaagcac
    39061 tagcttagcc cttgctgaca tcaaaaaatc cctcccaatg tactgacccc caaaagttgg
    39121 acacgacata ttagtgaaag gatttagttc tgtattgcac agggctaagt ccttttagct
    39181 ttgctttaat gcgtttgttg ttgtagtaaa aaatgtaatc tgtaat
//
LOCUS       DARYJX010000020        38469 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYJX010000020 DARYJX010000000
VERSION     DARYJX010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38469
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(37..1368)
                     /locus_tag="TU257_001001"
     CDS             complement(37..1368)
                     /locus_tag="TU257_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL0834020.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TU257_001002"
     CDS             complement(1459..2238)
                     /locus_tag="TU257_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL0834021.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TU257_001003"
     CDS             complement(2269..2913)
                     /locus_tag="TU257_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL0834022.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TU257_001004"
     CDS             complement(2919..3569)
                     /locus_tag="TU257_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL0834023.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TU257_001005"
     CDS             complement(3584..4774)
                     /locus_tag="TU257_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL0834024.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TU257_001006"
     CDS             4966..5868
                     /locus_tag="TU257_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0834025.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6765..7907)
                     /locus_tag="TU257_001007"
     CDS             complement(6765..7907)
                     /locus_tag="TU257_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834026.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7904..8767)
                     /locus_tag="TU257_001008"
     CDS             complement(7904..8767)
                     /locus_tag="TU257_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834027.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8778..9104)
                     /locus_tag="TU257_001009"
     CDS             complement(8778..9104)
                     /locus_tag="TU257_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL0834028.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9708..9872)
                     /locus_tag="TU257_001010"
     CDS             complement(9708..9872)
                     /locus_tag="TU257_001010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834029.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10111..11007)
                     /gene="era"
                     /locus_tag="TU257_001011"
     CDS             complement(10111..11007)
                     /gene="era"
                     /locus_tag="TU257_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL0834030.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11143..11544)
                     /locus_tag="TU257_001012"
     CDS             complement(11143..11544)
                     /locus_tag="TU257_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL0834031.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TU257_001013"
     CDS             complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TU257_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL0834032.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12371..12997)
                     /locus_tag="TU257_001014"
     CDS             complement(12371..12997)
                     /locus_tag="TU257_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0834033.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13052..13627)
                     /locus_tag="TU257_001015"
     CDS             complement(13052..13627)
                     /locus_tag="TU257_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL0834034.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13674..14774)
                     /locus_tag="TU257_001016"
     CDS             complement(13674..14774)
                     /locus_tag="TU257_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL0834035.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14877..15092)
                     /locus_tag="TU257_001017"
     CDS             complement(14877..15092)
                     /locus_tag="TU257_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL0834036.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TU257_001018"
     CDS             complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TU257_001018"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL0834037.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TU257_001019"
     CDS             complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TU257_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL0834038.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TU257_001020"
     CDS             complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TU257_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL0834039.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17521..18249)
                     /locus_tag="TU257_001021"
     CDS             complement(17521..18249)
                     /locus_tag="TU257_001021"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL0834040.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18548..19228)
                     /locus_tag="TU257_001022"
     CDS             complement(18548..19228)
                     /locus_tag="TU257_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834041.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19215..20003)
                     /locus_tag="TU257_001023"
     CDS             complement(19215..20003)
                     /locus_tag="TU257_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834042.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19991..20797)
                     /locus_tag="TU257_001024"
     CDS             complement(19991..20797)
                     /locus_tag="TU257_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834043.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20782..21723)
                     /locus_tag="TU257_001025"
     CDS             complement(20782..21723)
                     /locus_tag="TU257_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834044.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21801..23423)
                     /gene="nikA"
                     /locus_tag="TU257_001026"
     CDS             complement(21801..23423)
                     /gene="nikA"
                     /locus_tag="TU257_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL0834045.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23925..25565
                     /locus_tag="TU257_001027"
     CDS             23925..25565
                     /locus_tag="TU257_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0834046.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGKKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25809..26498)
                     /gene="rplA"
                     /locus_tag="TU257_001028"
     CDS             complement(25809..26498)
                     /gene="rplA"
                     /locus_tag="TU257_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL0834047.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26604..27029)
                     /gene="rplK"
                     /locus_tag="TU257_001029"
     CDS             complement(26604..27029)
                     /gene="rplK"
                     /locus_tag="TU257_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL0834048.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27265..28062
                     /locus_tag="TU257_001030"
     CDS             27265..28062
                     /locus_tag="TU257_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0834049.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28217..28567
                     /locus_tag="TU257_001031"
     CDS             28217..28567
                     /locus_tag="TU257_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL0834050.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28896..29288)
                     /locus_tag="TU257_001032"
     CDS             complement(28896..29288)
                     /locus_tag="TU257_001032"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834051.1"
                     /translation="MSPTERELKKEKEVLRNFIATIKLSYSEANEMEAKVYGADSFSK
                     LRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGHSRNIMKKYRLEFLDRLMGIQY
                     DVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(29726..32125)
                     /locus_tag="TU257_001033"
     CDS             complement(29726..32125)
                     /locus_tag="TU257_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL0834052.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            32245..32418
                     /locus_tag="TU257_001034"
     CDS             32245..32418
                     /locus_tag="TU257_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834053.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            32505..33311
                     /locus_tag="TU257_001035"
     CDS             32505..33311
                     /locus_tag="TU257_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL0834054.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(33467..34300)
                     /locus_tag="TU257_001036"
     CDS             complement(33467..34300)
                     /locus_tag="TU257_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0834055.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(34301..35026)
                     /locus_tag="TU257_001037"
     CDS             complement(34301..35026)
                     /locus_tag="TU257_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0834056.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(35086..36018)
                     /locus_tag="TU257_001038"
     CDS             complement(35086..36018)
                     /locus_tag="TU257_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL0834057.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            36164..36811
                     /locus_tag="TU257_001039"
     CDS             36164..36811
                     /locus_tag="TU257_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL0834058.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            complement(36867..37568)
                     /locus_tag="TU257_001040"
     CDS             complement(36867..37568)
                     /locus_tag="TU257_001040"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL0834059.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(37592..37840)
                     /locus_tag="TU257_001041"
     CDS             complement(37592..37840)
                     /locus_tag="TU257_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834060.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            complement(37840..38394)
                     /locus_tag="TU257_001042"
     CDS             complement(37840..38394)
                     /locus_tag="TU257_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0834061.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
BASE COUNT        11830 a         8872 c         6943 g        10824 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcactcac
     6181 atctaatgga gtactatcaa gaaaaagtta tttttaaaat catcaataac ctatctaaat
     6241 tttctaaaca atgccatata aaaagagctg gagtcaccaa gctctaattg atttttacat
     6301 gatgctctat aacaatatcg tttaaagatc attctttttt actagtatgt tgatcacatt
     6361 ttctaaaagc cagaaagaga cttgaatacc gagtcccttt tctttttatc tataaacagc
     6421 cttaaagaag cccagacagg ctgcggtaat tttcttaaca tgagcttcta ctatttctct
     6481 tgttaagccc tgctcacttg atgattcgtt atttttacca cctgaagact ctcctctaca
     6541 taggctactt tgtcatctag ttcctgcttc ttaacgatat atcatcgtct caattgatgc
     6601 cacttccctt atcatcttag aaaaaagcta atttctatac ctttaggtgt tctagatcac
     6661 aaaatagctt tctcaatcct atctaccttg caagaattca ttgaatgccc ttaacttttg
     6721 cagtaacgac aataaaaata gtttagataa cgatgctatt gatgttactg acttaccctc
     6781 tttattgata agtatgctaa atataagcaa agaaatgcaa aagctaatct aatcatgaca
     6841 ataactaatc catcaaccca aaaactgcca aaaaagccgt cataagcaag cttaagcatt
     6901 atgtttggtg tactcgcagt tgatacagat aaaatactca acaccttatg aggtattcct
     6961 gcttggaaaa tatccataag aaaacttggt acaaaaacac tagccgcaga caaggcaaaa
     7021 cctgtcaatg gagacttaac cttacttgaa ataaggatag tgatagccgt aatcaggata
     7081 agcccaataa actgataggt gactagattg ataaatgttc ccaaaagagt cattttttct
     7141 ggaaaagcca ttatattcac attgctgtta atccaataca gattgagttg aacactcgtg
     7201 tcccaaccac ttaatccaaa ataccaaaca aagaccgcta atattatggc gtaaaaagta
     7261 acaaacactg aggtgcttat caagtaacta cttattatct tggctatcgt aagtttatta
     7321 cgaccatacc tagttgtcaa taaaatagga ttcatatttt tagcagtatc accggaaaaa
     7381 acaggagcga tgaagtaaac agacaaaaga agaagaagga tataagcact atttatgacc
     7441 agaaaaagct gattccaggg tgcaaaatta cccaacttca gctctttaaa gggaagataa
     7501 gagccaagag ccgtttgaga ttttggggtg atcttactga aatcaatagt ctcttctttt
     7561 ttcaaattaa aataataatc tctaaatttt ggatcaaaat ggctagttac atagtagcca
     7621 tacacattga agacaggatt ttttgagctg ccacctagag tataatcttt gattgttcta
     7681 attaataact cattggacaa ttgaccggta tgttcttccg caaatcgctt gtttatctca
     7741 acagcatctc ttccatgaat tttatctatc gaagaaccac tgatttgtcc attaaaaaag
     7801 ttgatataaa ataacccaaa gattgctaat aagctaacaa taaacattcc caaaactgat
     7861 ttggttcgga tcagtttttt taattcaaat ggtaagagag ctttcataac acctgttcct
     7921 ctctaaagtg ataaatgtat aagtcttcta aggttggtga cactagttga gccaactgat
     7981 ttggtttctc atcactaacc acacgaaaaa cacgactaga tgaaactagt ttctcattga
     8041 ctacagcata ctgaccatgc cttggtaacg gcgaaccatc agagacagaa aactcccaga
     8101 ccttgccaaa gatggttttc aacaattctt gactactact cttatggata aattgaccat
     8161 tttttaaaat gataatctcc ttagcaatag cctcaacatc agagacaata tgagttgata
     8221 agataataat tttgttggcc gacaattcgc taataatatt gcgaaacttc accctttctt
     8281 ttgggtctaa tccaactgtc ggctcatcta aaatcaagat tttagggtca ttgagtaagg
     8341 cctgggcaat accgagacgt tgcttcatac caccagaata agaggcaatc cgcttcagac
     8401 ggacatcata tagatccaca agttttaaca attcatccgt ttcttgcttg gctttatgtt
     8461 taggtattcc ttttaaggct gccatataaa gaagaaagtc tcgaccagaa aaacgaccat
     8521 aataactaaa ctgttgaggc aaaaaaccaa tatgctgata aaattcctct gattgaggtt
     8581 tgtgatccag taaaatctct ccttcatcag gagtcgtaaa atgactaatg agattgagca
     8641 aggtcgtttt ccccgtccca ttagccccta aaagtccgta aaggcctggg gtgaattgag
     8701 tagtaatcct tcgcaaaata tttttcgatc cgtagctctt actcaattga tttaattcta
     8761 ataacataga accctcctta aatgagtcta ctgagcacct gtaactcagt actcagtaga
     8821 cttctcctgt acgaaatcct gctgtctgta acctttatta ttctcgtagc ataatcaaat
     8881 ccagagattt tcgattcatt aatgaaatat tgacgatgac acctttttaa tttcccagca
     8941 ctttctccct caatctgtct cagtgacgta gctgccccaa attccccttt tagggtaaca
     9001 aatactactg tgtgaggctt agatgaatgt gttgtcacat cataggtttc agagattggt
     9061 aatttaacaa ctgacctatt cttatataaa ataacatatt tcattgacgt cctccttctc
     9121 tatttatatc ttaatacaag tacaagcatt gagacggtaa agtctcaaat ggtatctatc
     9181 atatcctgaa tggtatcaca gtagctgttt aagatgtcat agaggcattt gagaaatgta
     9241 acctgttttc ctttcgtttt ttgatcatat gatattgtat tagttcggag aaccatggta
     9301 atcattcaaa tcttacataa acctctcttg ggatatggta ttagcgtcta tattaattac
     9361 tacttcaaca gacacctttt taaagctgct aaaattgtca gtggcaaaca aataggctat
     9421 aggtataaat ctcacactta ttttatcata aaatcattct ttttatcatc taatcaaatg
     9481 tacaagcact ttaaagttat tctcatgact ctattattct tattggaagc catattaatt
     9541 acgacgacat tttcagaaat cattatcgtg tgtttggtat catcgacaca accgctaata
     9601 aatcgtttaa atgtatccaa aaccaaattc atgattacct gttcaaagaa taaccagagg
     9661 gcttactgat tgctttaaca aatatttcta gtcttctcat tttgtactca tataaactca
     9721 tctactctat taaaaattgc tgtgaacaga aaaaccttct caacctgttt cagttttata
     9781 gccgtagtta gtttaaagtg aaaccaccct gcattttcta tacctaaatc caattgactt
     9841 gctttttcag catcaacagt catgctatcc ataagataac acaccacgat gtgttgtgat
     9901 tattgttctt ctatatttag ccttacctcc tgaaaacaaa aaaagagaac accttttaaa
     9961 tgttctcata taagcaatct tatatattaa atgaggattc gatctaatga caagacagcc
    10021 ttattgctac caataatgca gcttaccaaa caagggcaat cagtataagg gttgctaacc
    10081 agctctgctg acatagcctg ctttgagcga tcaatactcc ttctgattat agccaaagtc
    10141 agctaaatca agctttttgt cacgccagtt tttcttaacc ttgacccagg tctccagata
    10201 gaccttatcg cctagcatta gctcaatatc acgccttgcc agcttaccga tttttttgag
    10261 catggcgcct tgttttccaa taataatgcc tttttggctg tcacgctcta ccatgatggt
    10321 aactcggata tgcaccttgt cagtcacctc atcacgcttc atcgaatcga ccacaacagc
    10381 aactgaatga ggcacctcct gctgtgtcaa gtgaagcacc ttttcacgaa ccatctcaga
    10441 aacaagaaag cgctctgggt gatcagtgat ttgatcctct gggaaatact ggaagccctc
    10501 ttcaaggtta tcctttaaga gctgaacgag cgtttcgacg ttgtttcctt gaagtgctga
    10561 aataggaaca atttccttaa agtccatctg actacggaaa tcatcaatct gctccaataa
    10621 ttggtctggg tgaaccttgt caattttgtt gatcaccaaa ataaccggaa tacgagcagc
    10681 cttgaggcgt tcgataatca tatcatcacc cttaccacgc ttttcatcag caggcaccat
    10741 aaaaagaacc gtctcaacct cacgcagggt actataggct gattccacca taaaatcacc
    10801 taaggctgtc ttaggcttat gaatgcctgg cgtgtcaata aaaacaattt gctctgtctc
    10861 tgtggtatag attcccataa ttttattacg ggttgtctgc gccttatcgc tcataacggc
    10921 gattttttgt cccatgacat gattcaaaaa cgttgatttg ccgacatttg gtcggccaag
    10981 aatggcaaca aagcctgatt taaacataag ctactaaggg cctaaaggat cagtcaaggt
    11041 aagaatcaag cagcaggcta ttcacctgat tgctttccta aagcttatac tcctttcctg
    11101 cgctgcacta tcgcacagga tagcccattt cctttcattt ttttaatggc ataacattcg
    11161 ccaaattttg ggaacaaaga taatcagccc cgtcaaaaca gcatagcctg aaatgaccag
    11221 gacagcacct gcagccatat ccttggcatg cttagccagc atggagaaat ggtaatcact
    11281 tgccaagtca accacatttt caatagctga attgacaatc tctaaggtaa tcaccaaaaa
    11341 aatagccagc aataaaaaca gccattctat agcagaaata ccaaaaacaa tcccagccaa
    11401 agaggctaac agggctgaca aaagatgact tcttaggtta cgctcctcct taaaggctgt
    11461 cagaacccct gtcaaagcaa attctaagct ggcaattact gttctgtttt tccatttgcg
    11521 tttattattg tcttgtgagg ccataagcag tcaaaatctc ttcctgtaac gtaaacatct
    11581 ctttttcttc ctcaggagtg taatgatcat aaccattaat atgcaaaaaa ccatgaacag
    11641 ccaagaagcc catctcacgc tcaaaggaat gcccataggc ttctgcctgc tcatgggctt
    11701 tgtcaacaga aataaacagc tccccaatat aagcatcaaa ctcctgtatc atacctgcca
    11761 agtcaggatc aagctccaaa tcctcttggc taaaggcgat cggaagctct ggcttgtact
    11821 ccagagaaat cacatcagtc ggacgatcag tatcacgata ttcaagattc aaggcgtggc
    11881 ttctatcatt ggtcacaaag gtaaccgcca tttccttgtc ctctttacca attgttttgg
    11941 cagcaaaatt gagcaaatca atggtttgct ccatcatctc ttgagaaacc tgcttagttt
    12001 catcaatcat ctctatatac atcattatat gaagaggtcc tagcaagaca ggtccaaaca
    12061 aacaccacac tgctaggtca aaaagcttga tacctcttat cctttcaaca tcatttcagt
    12121 actttctttc cattatacca caagaaaaaa gaaaaagcag gcattagtct agcctgctcc
    12181 aaaagaagcc ggaataatga caagatcgtt gataccccag cagctgctgt ttctggaata
    12241 cccagagcct gctgcgcaga atacagtcct cttagatagc tgggactcct aggattacaa
    12301 tagtagataa gcctttagac cacttccatc gcctaaaaac taatcctaaa cggctttccc
    12361 ttagatacca ctagctgctc tcaaagctat tgtggaggta acgatctggc ttattggctg
    12421 acgccagtga tttctgcttg tcataatctt ctttggttaa ataatagtgc agcactgtca
    12481 caaaacggtt ggaatcaagg tgatcacgct tagcatatgg ctcttcatgt gaaaagcaca
    12541 tgccgctttt agccataaca cgtcccaaag ccggattggc tttatcatgc ttagcaatca
    12601 cacaattcat gcctaaagct tcaaaacaca agaccagtac agccttgaca gcctctgtcg
    12661 catagcctct tccccagtga tgcttatgaa gacaatagcc aatctcagct ctacctaaat
    12721 ccagctgtat atgatgaaga tcaagcgtcc caataaagtc tcctgtttcc tttaacacaa
    12781 tcccccaccg tccaagtgga ctagccagat agacagaagc aatgacttga cgggtctcct
    12841 caattgtctg attggctgga aagctatacc tgacagtctc ttcatcagaa gcataatcaa
    12901 acatggcttt ggcatcatcc aaggtcactg gacgcaggca tagacgctct gtctcaagat
    12961 acctatgctc tgctagtttt tcaaaaaagc ttgccactac tactctccct ttcctaaaaa
    13021 tctaactcac ctaacagcat gactgcctgc cctagccgcg taaaatctgc ctcaccttat
    13081 cctttaaaac aggaaccagc tcctcttcaa accaagcatt tttagccaac caaagctgat
    13141 ttctaggaga tgggtgaaca aggggaaaat aatccggaag atagtcctca aaatgctgca
    13201 ccgtttcggt aagattgcgt ctacaacctt caccaaggta atattgctgg gcatactgtc
    13261 cgaccagcac caccaattca acctgaggca tcaaggccat taacggacca tgccacttgg
    13321 cagcaaagcc ctttcgcggt ggtaaatcac ctgattttcc cttaccggga taataaaaat
    13381 ccataggaag aacgccaaac aagcccgact gataaaaggt cctgtcatca acacccagcc
    13441 aagctctcaa gcgaactccg ctacgatcat tccagtacag acgcgtctcc tgagctacaa
    13501 taccaggcgc ctgaccaaca atgactatcc gagcggtctg aggagctgca taaagtggtt
    13561 cgataccttt tttggtatag tcacgattgg caggatcagc cataatcgct tgcaatagct
    13621 ctgtcatgat accctcactt tcataaaagg ctcttcaggt gaagagctct tttttacgat
    13681 ttgtcttctt taggcagctc tccaatgacc tcataggttg ttaagcctga cgtagactga
    13741 cccgtctctg ttttaggccg atctggagcc ttagtctgat gttgcagctg attagggctg
    13801 ctttttaatg actctgcttt tgaacctaca gtttcatagg ccttaataat ctcagcaaca
    13861 acagggtgac gcaccacgtc cttggctgaa aaatgcacaa aatcaatctg cttgatggcc
    13921 tgcaattttt gagctgcatc aatcaagcct gatgtgatat gacgcggcaa atcaatctga
    13981 ctaatgtccc cattaacaat cattttagac tgaaaaccaa gtctggttaa aaacatcttc
    14041 atctgcatga tggtcgtgtt ttgcgcctca tctaaaatca caaaggcatc atctaaggtc
    14101 cgaccacgca tataagccaa gggagcaatc tcaataatat cacgctccat taaccgagta
    14161 gtctgctctt taccaagaat ctgataaagg gcatcgtaga ctggtctaag gtaaggatca
    14221 accttttcct tcaaatcccc tggtaaaaag cctaagcttt ctcctgcttc aacagctggg
    14281 cgtgtgagaa tgatccgctt aacctgacca cgctttaaag cagtaactgc tagcgtaact
    14341 gctaaaaagg tctttcctgt tccagccgga ccaataccaa ataccacatc atgatgcttg
    14401 atactatcaa cataggcctt ttgccctagc gtcttaacac gaattggctt gctataaaag
    14461 tccttgataa tctcttcctc ataaagagca acaaattgat caagcctatc tgaatccgcc
    14521 atagacagcg cagtcaccac atcagaggta ttgataacca tgccacgccc caccaaaact
    14581 aaaagggctt gtatcgtcaa acgcgctagc tcaacagccc gctcatcatc accaataatc
    14641 tgaactcgct cagttctagc atgaatcaca acattgaggt gagattctat catcttcaaa
    14701 tggcgctcat tgctaccaaa aagagctaac agatcatctg ggtgattcaa gctaatgtca
    14761 gtcgaataat gcaaatttgt cttccttttc catctataag taactctatt ataacaaatt
    14821 ttgctataaa tcgggaataa gacccagctt taaagcctaa aagagctagc ctatggctag
    14881 tggctaaggt aatcctccca aatctggtca aactgcccca gattgaatga aaagctcgct
    14941 tcctcttcaa ggtaacgact gatggtctca aaatcatctg tatgctttgg aaaggtcggg
    15001 tcctcaaaaa ccaaatcagc taataaagca gcaggcttat tagatgtcga gttgcgctga
    15061 gccatcagcc aagtgtaaaa cgcctttctc attgccaatg ctcctccaaa aattgatgac
    15121 gaatagcact actttgtgca taacgctctg gattcttttg ataaaagccc tgatgatagt
    15181 cctctgctag ataaaaaggc tctgccggtt caatgcttgt cacaatgggc tggtcaaagc
    15241 gccctgaggc ctgcagggtc tgcttggacc gctctgcaat ttcccgctgc cgctcatcag
    15301 tatagtaaat caccggccga tagttgtctc ctctatcctc aaattgccca aaggcatcgg
    15361 tcgggtctgt ctgagcccag taaagctcta ccaaatctga atagctgatc agactcggat
    15421 caaagataat ctcaacagct tcagtatggc ctgtcgtctt tgagcaaacc tgctcatagc
    15481 ttggattgtg aacatgccct cctgtgtagc cacttctcac tgataaaata cctgcctgct
    15541 cctcaaaagg ctgcaccata caccaaaaac agcctcctgc aaaaattgct ctttccatac
    15601 ctaatctcca ctttctttgt ccttacatta gtgattttca ttgtaacaaa aaaccttgcc
    15661 agaggcaaag cttaatataa aacaagtcac agactcaaag taacaagact cctcagccca
    15721 actagtgcct agcactaagc agtactgtca agcagccact actagatcaa gagggccaca
    15781 cagagctttt tcgacaacaa aaatgattgg cgctttaaaa caggctatca gctaagctcc
    15841 acactcaaaa taaggaagct agctatactg ataaaggata agtcttagca acaccgatcc
    15901 agcttatgat tataggctaa gagacagaca gctccctatg atatcagctc agttcctgtc
    15961 acgtcctgct tgatcttgtt agccttcatc aaaccaccta aggccttttt aaattgaccc
    16021 ttggaaatcc caaaggttgc cttgatatcc tctgggcttg acttatcatt aagagtcatg
    16081 tagccaccat tagacttgag ataggtcaga atcatctggg catcgttttc cagcatttca
    16141 aaggaacgcg gctttagcga aaggttgagg gtacggtcac gttctctaaa gccaatcacc
    16201 cgagcggtca aaacctgccc caaacgaggc tccgtataac gctcgctagg gtggataaag
    16261 cccagcatat tattttctgg caggtaaaca aaggtccctg atagcttcaa gcgatagaca
    16321 atagcaggca ggctttgatt ttgcatgtta tcataggctg gactagcaag cctttgaaat
    16381 atctctggct cagctggcaa accccagata cgatcttttt tgtcaaccac aagcttaaga
    16441 taaagcctgt ctcctttttt aggccaaaga tcctttagct ccggcaaaac atctaaggaa
    16501 accacaatct ccttatctgg aataccagta tcaacaaaca ccccaagatc acgacggaca
    16561 gtggtcacct cgccccagcc ataatgatca cgccttgcgt caataggctt cgtggtcaag
    16621 cgtagtcttt gcttcatatc tgtatagaca aagcccttaa ccatatctcc taatctatga
    16681 ctgccttcct ccttagctag agcaaagctc agcccctcct tttggacaag ataaaactga
    16741 ctattttctt cttttactaa gccagtgata actgttgcta ataaatgatt catatctttt
    16801 tgttctttct tttaaaaaat agggacaagt ccaaagcagc tgctttttag ccttgtcacc
    16861 tatcctgtta tgcctgatgt gtattaggtt acgcagctga tctagcttaa tgatcagata
    16921 agccgcttaa actgaaagta attccttttc tttgtcagca gtcattcggt caatctcttt
    16981 gacagcctca tctgttgctt tttgaatatc cttttccaag gcttttaact catcttcagt
    17041 gatttcctta gccttctcct gctttttagc ctcgtccata gcatcacgac gaatattgcg
    17101 aatcgaaacc ttcgcagtct caccaacctt tttcacttcc ttggctaatt ccttacgtgt
    17161 ttcttctgta agcgctggaa taaccaagcg gatgacagag ccatcgttag ctggtgtaat
    17221 gcccaaatca gaagcattca aggcacgctc aatatccttg attgatgatt tgtcaaatgg
    17281 tgaaatcaaa agcacacgcg cctctggtac tgtaatagaa gccaattggt tcaacggcgt
    17341 tggtgcacca taataatcca cctgaatacg atccaaaagg ctagcattag cacgacctgc
    17401 acgaatgctt gcatactcgc gtgctagtga gtgatgtgac tgtgtaaaac gttctttcgc
    17461 agtttcaata attgcatttg ccatgattgt ttttctcctt aatcctttag ctctaaaatc
    17521 ctaatcgcag gccttatttg ataccgttgt gccaatatgc tctccaaaga ccacacgctt
    17581 gatatttcct gcttcattca tattaaagac aaccaaatca atatcattat ccattgacaa
    17641 ggttgaagct gtcgcgtcca taatcttgag accgcgcttg ataacctccc catgagtcaa
    17701 ttcatcaaac ttaacagcgt ttgcgtcctt tcttgggtca gcattgtaga caccatcaac
    17761 accattttta gccatcaaga tagcatctgc ctcaatctca gcagcacgta aggccgctgt
    17821 cgtatctgtt gaaaaataag gtgacccaat accagcaccg aaaacaacaa tgcgcccctt
    17881 ttccagatga cgaagcgcac gacctcgaat ataaggctct gcaacgtttt gcatgggaat
    17941 agctgtctgc acacgagtat caacgccata atgctgaagg ctatcagcca ttactagagc
    18001 attcataacg gttccaagca tgcctgtgta atcagcctgc acacgatcca taccagcctc
    18061 tgcagcaggc tcaccgcgcc agagattacc accaccaata acaagagcaa tttcaacacc
    18121 tgaattgtga acttctgcga tctctttagc aatcgactga accgttgtta tgtcaatgcc
    18181 aacaccctta tcaccagcca aggcctcgcc agacaatttg attaaaatac gttgatattt
    18241 aggtttcact atttatgatc tccttatttt gtccctacca ttctaccaca aaacaaaaaa
    18301 atttaataga ccaatgcaag agaggaaagc gaaatttttg acgatccttt tatcaagatc
    18361 cctttgagca gcaaaaaaga tgagtcatta taaaaagagc attatcgtat ccgaatagca
    18421 cagttataac ctattaatac gacaaaaacc agaacaacta tgacaaaaaa cgccgtaaaa
    18481 aagacttaaa atcaagcctc aagccagact agattctaag tcgtgctata ttgagagatg
    18541 atttgtttta gttatctagc ccaatgccgc cacaagaagt ctgaggctcc ttatctctga
    18601 cagcaactag cctcccctgc tccagcagca gaacacgatg acaaatggcc tgacagatat
    18661 tagcatcatg cgcaataaaa atataagtca gttgatactc ctgctttaac tcatagagca
    18721 agtccaatag ctgcccttgg gtaatagggt ccaagccact caaagcctca tcaaaaatga
    18781 tcacctccgg ccttaacaaa agagctctcg ctatacaaac acgctgtagc tgaccaccac
    18841 tcagctctct ggccttttta cccagatgag tggcgtcaag accgaccgca gctagtattt
    18901 gaacaacctc ctctaaggca aagtccttag aaagggcctc tgtcaatatc tcttgaatag
    18961 taaagagggg attgactgat cttagcgcat cctgaaagac aagtaaaatc cgaggtccac
    19021 atacttttac agaatagggc tgaccatgaa agagcacctg accagctgtc ggctgctcta
    19081 gcccaatgat taacctagca agcgttgtct tgccactacc actttctccc ataatcccaa
    19141 ggctctcacc cttttccatt tgaaaatgac aatctgttag cactggcttt tgatgaaagc
    19201 tcttataaac atgtctaaac tctatcatag cgtatcagcc gatcataatg attttgcaaa
    19261 agcaactcct tggtggcagc ctgacttggc cgatgaaaaa tcgactcaac acttccctgt
    19321 tcgatgattt ttcccttact catcaccagt agttgccctc ccaaagtctg tgccaattgg
    19381 taatcatgcg tcactgtaat aatggttttt cccttgtcct gcaataactt cagcatccgt
    19441 atgatattag aacgattggc atcatctaaa gcagaggtag gctcatctaa aatgataatc
    19501 tgtgggtcta agcacaacaa aatagctagc attacccgct gtagcatacc accacttagc
    19561 tcaaaggggt acttcctcag cagctcctct ggctgctcta gatagagctc tcgcatgaaa
    19621 ggcagagccc tttttagaca ggcccttttt gaaagtctct catggcttcg gatggtttca
    19681 aggagatgag cctcaatggt ctgaaaggga ttgaacatcg ccataggatt ttggaccata
    19741 taggccatgt ggcgccctct aatgctctgc cattgcttag catctaattg atctagtctc
    19801 atatcttgac aggtaatcct ccctgtcatc tgtacattcg acgggcattg accaattaat
    19861 agcttagtca agagggtctt gcccgaacca ctcctgccaa caatcaccaa ggagctcccc
    19921 aagggcaact caagattgag cttacttaat agcacatcag agccattata agccgataaa
    19981 tcattaacaa ttaaccgttc catgttttcc tccacccctt agcatcagcg taatcaccta
    20041 ggctgttaaa agctagcaca gtcactaaaa tggcaagccc tggtgacatc atgagccaca
    20101 gagctgtcct aaaatagctc cttgcatcat gcagcatcat tccccattct gtcacattgg
    20161 gctgaacacc gatacccaaa aaagaaaagc ttgagatcat gagaataata ttgccaatat
    20221 tcatcaaagc caacactaca atcggccgat aaacaaatgg caggatatgc ttttttaaga
    20281 tatgccgcac agataagccc attgtctgcg cactaatgac atatggctct gccttagcgc
    20341 ttttgaccat cgtgaccatc agcctagcat aatacagcca ctctaccaga acaatagcta
    20401 ggatcatgtt gcctatgccc tgcccaagta tccccattgt agctagcgat agtaaaaagc
    20461 taggaaaggc agaaacaaca tcagctagcc acagaaaagc tgcctcgagc cttccttgat
    20521 accagcctac aaccaaacca accacagcac caatagatag ctctaacaaa ctaatagtaa
    20581 ccgccaaaag caaggaatac ttagccccat ataacaagcg cgacagcaca tctcttccca
    20641 attggtcagt tcctaataag tgctgctgac taggtggcat gagcttacta gcaacatcaa
    20701 cagcatgagg atcaaaggga gcaagataag gagcaaacaa gacacagata aacaacagca
    20761 atagcataac agctgaacca attacgtatt tgggcatgct tcctcctttg tcttgcgcag
    20821 acgagggtca ataaaagaca ctagctcttg agttatcaca tggtgtagta aaaacaaagc
    20881 accaaataag agcatacagg cctgaataac cggaatatct gctgctttca gactcataac
    20941 aaatagactg ccaataccat tccatgagaa aatatcctca acaataatag agcccgtcat
    21001 caaataaaca aaggtcaagc tcaagcctgt tgcaatagca ggaaaggcat ttctaatcag
    21061 gtgatgctta acaatataat aggtcttaac ccctcttagc ctggcatttt caacatgcag
    21121 actcgttagc tgctcactga ttgcctttcg tatcaaggca gtatattgcc caatcaagga
    21181 aaagctaagc gtaatactcg gcaaaatgag gctgctggca cccgccttgc ctgacacagg
    21241 caggagattt agcttaacag aaaaggctat aatcaagaga tagcccaacc aaaagctagg
    21301 cattgacaca gcgacaaagc tgaataaacg caccagccga tcaaacaagg aatgctcaaa
    21361 caaaccactg cctaccccca aaggaaaggc aatcacaagt accagtaaaa aagaggtcaa
    21421 gcttagcatt agcgttgcta aaaagcgctc caccaccaaa ggcaggacag ggacctttaa
    21481 cacgtaagag gtcccaaaat ttcctacaag aatgtcagat aaccaggtca catactgctc
    21541 ccataaaggc ttgtctaagc ccaaatagag cctagcattg tgaagagctt ctggtgtaat
    21601 actgatctta gataggcgca aatactgctc tgccgggtta gcggaggata gcttaaccag
    21661 aacaaaggtc actatcgaaa tcattagcaa ggcgccaaag gtagaaataa gcttcttcat
    21721 catattttct ctcaaccctt cactaagaca tcagacaaga attgtcagga tagtcactca
    21781 caaccagttc ctctgctcta tcaattcttg actgccttat cagcagcact tttttcaatg
    21841 taacgcaatg gaagggcatt ttcctctggt gcaaagcgca ttgtcttaaa atctcccttg
    21901 cgatatactg aaacaactga ctgataggtg agtggaatat aaacagcctc atcatgcaac
    21961 aatgacaata cctgcttata gcccttgtct accttatccc catctggctc aatcaaaaca
    22021 gatttaatca ggcgatcaat ctcagccttt gatggcaaac tctccaaggc aatattttct
    22081 gggtgaccat gatccgcttt tgccgttaag gctgtcatcc aagcatgagg atcccaagga
    22141 gctccccatg aataggtcag catcatatca aactgccctg tcttggcatt agcccagtag
    22201 tcatcctcct ccatagctgt caagaccaca tcaatcccaa gctttttcca ctcgccttgg
    22261 aaatattcaa ccaaatcctt gtctgtcgct ttagttgaaa tataaggcac ctgtaaacgc
    22321 aactgctgac catctttttc cctaatccct tcttggtttt ccttccagcc agcggctgtc
    22381 agcatgtcct tagccttttg gagattgtat tcataaggaa ctaagcccgc atcagcatgc
    22441 ggtgttgttt ttgaaaaaat ggtatctgct gctgtctctg ttcctctaaa ggtgtgctta
    22501 gcaatagcct ttttgtcaac cgcatggttc attgcctgac gaacccgctt gtcctgaaac
    22561 actgactgct tagcatttaa cagcaataaa cgagtcgaca tgggctgaga aacatcagta
    22621 acatacttct tgtccttagc atactgcaca aaggtatcaa gactaatcag accatttcca
    22681 tagatcaaat caatatcccc agcctcaaat gctaaggctc ttgtctcagc atcaggcata
    22741 atcttgatgg ttacttcctt tagctttggt ttttctcccc aatagctctc atgacgtgta
    22801 aaggtaatgt actcatttgc ctttttctct ttaacaaccc attgacctgt accaatcggc
    22861 tttttaacat tgtgcttatt ggtgtcatcg ccatcaggaa aaccagcatc agccaaaaac
    22921 ctaatcggtc tgatcattga caaatcatac aaggtagcgc tataagcctc ctttagctta
    22981 atctcaaagg tatgatcatc taaagccttg tagctatcca attgattggt aaagtgaaac
    23041 caattatgat tgcccttatt ctgctcagag aaaatcgaat caaaattccg tttaacattt
    23101 tgagcattaa aatcagaacc atctgaaaat ttagcctgtc tcaggttaaa ggtataggtt
    23161 ttgccatctg ggctaatcgt ccagctctct gctaacgccg gctcaatatt acccttgtca
    23221 ccatatcgaa ccaagccctc ataaaccatg tcttgaataa caaactgatc aggattgtag
    23281 cgatgaggat tgacatcacc aaaatcctca ccccaagcaa tcctcaactg atccgtacgg
    23341 taagaggcct gcttagcatt ttgacaggcc gtcagcagca aagcaaaaaa gaataacaat
    23401 agcacattca atttagtttt cattatgtca ttaactttct aaagatatta atctatctaa
    23461 ttttagatgt ggtttatcac aaaattaagt atggttaatt taatcatttt atagccctct
    23521 tgtcaagaaa aaatgagaca aaatcagcct agaaaaagcc agaaggctac aaataagcaa
    23581 atcgtcaaaa tcatgaacac ttcaggcttg ctgaggaata ttttctaatg gttattagaa
    23641 ataatgaaca attacctaac aaaagactcc aaaataaagg taaaagacga acattcacct
    23701 tgctgctcag ctaccaagac aaacaatcct gatagcatca attttcttta ggctcttagc
    23761 aattagttgc aatatcagat aattttgaat ttaattaaaa aaaacgaaac tacggagacc
    23821 aattatcaga aagctattca cagccagcaa agggcatgct aaagtattat ctggaaaaag
    23881 aaaggcttag gaatgattat ttctaaacta aaaggagaga gacaatgaaa aaaacaatga
    23941 agaagatgct agcagcctcg acgctctgta tcatcatgtc aggcagcttc atcagcggct
    24001 cagctagagt gttagcggag gaatattatg ggtggaatga tgtcactggg tctaagtcac
    24061 catttcctct atacgtgaca ccaaaaaatg gagataaaaa tataaaagtt caacaaacgg
    24121 ttgtttactg ttttaacagg gatgggcaat ggccagaaaa ttgggaaaaa cggatatatg
    24181 aatctcctga taaagttcca cataaattac ccgaatataa taaaaagtca ggaagcgata
    24241 atctgtttca attacttaat cccaaaatta agataaaaaa tccaatggca gctttattag
    24301 cggttttgga agatggatat cctacgtcat cttcttcagg agtaaatcaa agaacaactc
    24361 agctagctat ttggcatttt acagatggat taagcaatct tgcccaattt catcttactc
    24421 cggaagaaac ttcagcttat aacaagttga tagaaaaagg gacaaatgct tctaatcaaa
    24481 gtgaaaataa actattaaat aaaactttag atatttattc ctatatagat gggactggtg
    24541 ataagaaaca caattatcaa caccttcttg gctccactcc aattcctatt gataattcta
    24601 aagaaaataa atgtcaatgt acaaaagttg acttaatgcg aactggagat ggggttaaaa
    24661 tcattgttta tgttgataac aacggaaata atagatatga caacggcgac aaaatgctaa
    24721 aagaagaaac tatcaaacat ggtcaacgcg gacctgctgg tgaatctggg aaaccagggc
    24781 ctaaagggga tcgaggagaa actggagcac gcgggccagc tgggcctcag ggcaaacctg
    24841 ggaaacaagg acctagaggt gataaaggag aaaccggaga acggggacct caaggggaaa
    24901 aaggtgaacc tggaactcct ggtcctaaag gagaagacgg taaagacggg gctcctgggc
    24961 gtgacggaca accggggcct aagggtgaaa aaggtgaccc tggaaaagac ggacaagatg
    25021 gaaaaccagg ggaaaaagga gaacctggaa ttcctggtcc taaaggagaa gacggtaaag
    25081 atggggctcc tgggcgtgac ggacaaccgg ggcctaaggg tgaaaaaggt gaccctggaa
    25141 aagacggaca agatggaaaa ccagggaaaa aaggtgaccc tggacgcgat ggtaaagatg
    25201 gagaaaaagg cgaacgcggt gaacaagggc ctaaaggaga acgcggtgag cagggacctc
    25261 aaggagagcg tggggagcaa ggacctcgtg gggaaaatca tactcctacc ccagacccaa
    25321 tgcctgagcc ggcacctaaa ccagaatcca aacctgaacc taagccgaca cctcaaccag
    25381 aggttaagcc tctgccagag actaaacctc aaaaaccaac caagccgtca gcaatggcta
    25441 gccaaccaag tagcaaagca ctaccaaaaa caaatgacac tagcggctta atgactgtac
    25501 ttggaacagg cttgctctct cttcttggat taggcttcct ggcaaaacgc aaaagaaagc
    25561 aataactaac acataatcat tagtaatcca ttcattatcc atttacaagt tatcataaaa
    25621 aagccttatc attccttgac tggtatgata aggctttttg tttaccctat atagctctac
    25681 ccttactcca aaaatcactt aaccctagga aaaggctgac tatcattttt ggccaaaaaa
    25741 agacagacac caattcatga tgtctgtctc aaaaccaatc ccttttaggg tcagtcctta
    25801 attacttatt aaaatgaact tggatctacc ttgataccca caccttgtgt agttgtgata
    25861 gatacgttag tcatgtaagt accctttgca gtagctggct tagccttaac cattacctca
    25921 tggaaagcct taaagttttc aaccaacttg tcagcgtcaa atgatacttt accaatgata
    25981 gcttgtacgt tacctgcttt atcagcacga taggtaattt taccaccctt agactcttca
    26041 accgccttag caacgtccat tgttactgta ccagttttag ggtttggcat caagttacga
    26101 ggtccaagga cacgtccaag acgtccaaca atagccatca tatctggtgt tgcaataaca
    26161 acatcaaaat caagccagcc gccattgatc ttagcaacaa ggtcatcttc accaacgaag
    26221 tctgcaccag ctgcctttgc ttcttcagct tttgctccac gagcaaaaac aaggacacgc
    26281 tgagttttac cagttccgtt tggcaacacc atcgcaccac gaatttgttg gtctgccttg
    26341 cgaacgtcga tgtttaagtt ataagcaact tctacagaag cgtcaaattt tgcgaagtta
    26401 gtttcttttg cgagtgctac agcttcctct acactgtatg cctttgtgct gtccactttt
    26461 tcaagtgctg cacgcatttg tttgcttttt ttagccattt ttatcttctc cttgtaatgt
    26521 ggtcatatcg atttgattta aaaatctccc acgtcactca tctctatgat gaagtcttgc
    26581 gggtaataag ggcaggttgc tgattaatca gtaacggtga atcccataga acgagcagta
    26641 ccttcaatca tacgcattgc agcttcaatg tttgcagcgt ttaaatctgg catcttagtt
    26701 tcagcaattt cttgtacttg tgcacgagta actgtcgcaa ctttagtttt gttaggtgta
    26761 cctgatcctt tttcaacacc tgcagccttc tttaaaagaa cagcagctgg tggtgtcttt
    26821 gtgatgaaat caaatgattt gtcttcgtaa actgagataa caaccgggat aatcatacca
    26881 gcctgatcag ctgtacgagc attaaattcc ttagtgaatc ccatgatgtt gatacctgct
    26941 tgaccaagag ctggtccaac tggtggagct ggtgtcgctt taccagcagg gatttgaagt
    27001 tttacaagtt tttcgacttt tttagccatt tttaaaaatc ctcctgttgt ggttttggcg
    27061 gtaattcacg atttttacct cccacaggta tgctagagca taccttacca ttatacctta
    27121 ttagacagat aaatcaagtc attttcacaa aaatgttacc gcaaatagca gatgtctcct
    27181 atggcactag cagtacaagc atgtgaggct tccaaggagc cgcttctagt tgacttttaa
    27241 gcgttttttt attataacaa agctatgcat aagaaagtta cgatcaaaga tgtcgcacgc
    27301 gaggcgggag tttctgtggc tactgtctcc tatgtcatca ataacagaga agatcaaaaa
    27361 attagccctg aaacgcgcaa taaagtgctg caaatgatta atcttttaaa ttatcggcca
    27421 aaccaagccg caaaatcact cgtgacacaa aaaagacagc taatcgccct ttactacaaa
    27481 gagcacagct ctgttttaaa aagagcagag cagcttcact ttatcaccca gctatctgcc
    27541 tttctttaca caaagcacta tcacttgatt tgccttaatc aagaatacat cggaaaatat
    27601 gatgtagcag atgtcattct caccctagag gtcaccaaag aggaatttta caagatcgga
    27661 aatagcaact ttgttccttt gattgctatt gatagtatta ttgatgatcc cttatttttc
    27721 cagattaata gtgaccctca tctcctgttc aataaagcca gtgcttattt tgcaggggag
    27781 ccctttgaac tggttagcct gcctattcaa aaccaagaaa tcactcaagg actcgctcaa
    27841 cagtttgata acatttgctg gattcactct atttgcgaca tcgaaagcgt gtctaagggg
    27901 aatattctag ttattgatga tactgtcaat catattctta gtaagcacaa gaacaaacta
    27961 tacctgccaa gtatctcaga agctaagctt ctgaagcttt ttcaggctat tgagtgggct
    28021 tccaaaagag aagcaatcaa caatcataat attttggttt aaccatgata agagcttagc
    28081 aacaagcttg ctgctaagct ctttttgttg gtcaagaggc caactttatt taggtatcag
    28141 tcagtgtgcc agctctttta gccactaaaa gcaggaatta gtttacaagt ctaccaattg
    28201 ggtataaaat agacttatga tcatctacaa attaacagcc ttagccttta ttatcctgac
    28261 tcccttattc tctatgataa tgatatccct attgagactg ggacgaagag gccttaaatt
    28321 tcctgattta gccttaccac tttttgtttt tgaaattgtt attgtatcag gaaaattttt
    28381 cacccatcat ttactacctt attacctgat tgttatgtcc ttgttggcca ttgttatggc
    28441 actcttactg attatcagaa tccagcagtt ttcttaccgc cgatttttca aactattttg
    28501 gcgagtaggc tttttagtca cactactctt ttacctgatg ctagttggtc ttatttttat
    28561 cgtttagtgc cttaccagac atggcttcaa gcctagcagt ctgaatctgc caattaactc
    28621 tagcactatc actcaaaagg aagctgtctt tgaactttct gcttgagtgg gacttttttc
    28681 aaagcaatca atccatatca aaccagcatt agagcatgcg gcttgatacg gattgattgc
    28741 tttaagaact gttgtaaaat atcaaaaatt cagtttttaa taaagtccat tagctatttc
    28801 tacactaaat atcatttaag aaaacagagg ctaataacta gagttcacta taacctaaaa
    28861 tcaccaatac ctccgattaa cttaatttaa ccaaactact gtatatacca aagtttttta
    28921 cgtgtcatta taatacgttc agataaatca tctaatgcac gatctttgtt gagaccaaca
    28981 tcatattgaa tacccattaa tctatctaga aactcaagac gatatttctt cataatattt
    29041 cgtgagtgtc cttctggaaa atgctcatca ataagcgaac ttacaatctc aactttatta
    29101 ctaattttaa aatagcgact tttcaaagat tgtaattctt ctttaattgc tcttaattta
    29161 gaaaaactat ctgctccata aaccttagct tccatttcat tagcctcaga ataacttagt
    29221 tttattgttg caataaaatt tctaagtact tccttctctt ttttaagctc cctttctgtc
    29281 ggactcattc tatagtaata ttgacgccaa cgatattgag aagcgttgac tttttgatca
    29341 cttatagtca aaatagtcaa tgctactaca ctaaagaaaa atattctttt cgtttgcagt
    29401 ttctcctata cttcataatg tactatttgt atataaacac aacataacca agcattagta
    29461 tatcagaaaa ctttcttaaa tatgtgatat tagctaatct ttttttaaaa ctctctatat
    29521 attaaggtat tatggacata ttgacttagc agattagatc tgccaattag ctctagcact
    29581 atcactcaaa atgaagctgt ctttgagttt tctgcttgag tgggactttt tcaaagcagc
    29641 atatcaaaaa cccgtatcaa gccacatggt taagcttagc ttggtacggg tttgttttat
    29701 gatgagcctt tagatgagct cttttttaat tggtttgcag tacctttctt ggcttagtcc
    29761 cctcagctgg accaatgaca ccggcctctt ctaattcgtc cattagtcga gttgctcggt
    29821 taaagccaac cgatagacgc ctttggagca tcgaggcgct tgccttttgc gtttccaata
    29881 caagagcctt tgcttcctca aaaaggggat caccctcagg agctccgctg ctgccataat
    29941 cagagtcact aacctcaccc ggatcaaaat aatcatcata atcagcctct gcctgctcct
    30001 tgataaagct aacaatgcgc tcaacatcat catctgaaat aaaggagcct tgcagacgca
    30061 cagggtgatt ctcatcaatc ggcttaaaga gcatgtcccc gcgaccaagc agcttttcag
    30121 cgccattttc atcaagaatg gtgcgactat ctgttcctga tgaaaccgca aaggcaatac
    30181 gtgatggaac attagcctta atcaatccag aaataacatc aacagaaggt ctctgagtag
    30241 ctaaaatcat atggatacct gctgcacgcg ccttttgccc aagacgaata atagcatcct
    30301 caacctcctt actagccacc atcatcaaat cagctagctc atcaacaata acaacaatca
    30361 tcggcaaagg gatttgcttt tgctcagatt gcttgttgta ggcttcaacc ttggcattgt
    30421 agcctgcaat atttcggaca ccgaccttac tgaacagctc atagcgattt tccatctcat
    30481 caacaacctt ctgaagcgct ttgcttgctt tacgagggtt ggtgaccacc gggattaaca
    30541 ggtgaggaat gtcattataa acagacagct caaccatttt cggatcgacc attaggaatt
    30601 tgacctgatc cggtctagcc ttcattaaaa tactggagat aataccgttg actgcaacag
    30661 atttccctga tcctgttgag ccagccacca gcaaatgagg catgcgggtc aaatcaaagc
    30721 ttctggcact accgttgaca gccttaccaa gaggaatttc caataatttg tcatcagatg
    30781 tgttggattg ctcccaaagc tcgcggaaag aaaccgttgc aacctctgaa tttggtacct
    30841 ctatacccac aagggatttg ccagggatcg gagcttcaat ccgtacgtcc ttggctgcca
    30901 aggccaaggc caagtcatca gctaaattgg aaatgcgatt cacacgaaca ccaacagccg
    30961 gcttaacctc gtatttagtt acagatggcc caatctctgc ccgctccacc ttgacgtcaa
    31021 ttccaaagct tctgaaggta tcctctaata ccttgatatt ttgacgaaca aggtactttt
    31081 ccttgaattg atttttaggc ttatcagcag caaacagctc tatcgtcggc agcttgtaaa
    31141 gcagattggt ctttggcgtg aaatcgacct ccactgacag ctcctcatca tctgacagcg
    31201 gcgcctctcc tgcgattgct gaagcacccg ttagaggggc ttctggtaca gactcctctt
    31261 catctccaaa tgcctcaggc tcatcatcag cagggtgtga gtcataggcc agaatttccg
    31321 gctcaaaaaa tgcttcagac tccttctgat cagccatctc catcaatagg tcttctggct
    31381 ctgctaaaag ctcacctgtc tcaggattaa tcgcttgatt ggccagatat tcttgctcct
    31441 ccaaggcctc tcttgctaga cgctcctctt cagccagcaa tcgttgcttt tctcgctcaa
    31501 caaaccgctt ttccttgttt tcttgatagg ccagggatag cttttcaaaa agcgtcttaa
    31561 caaaatgact gacgtcataa atatcccaag gggtcattaa aaacaagccc agcaggataa
    31621 acaaaaaacc aataaaataa gagccaatat tagaaaacaa gaaggaaata ggcttgtaca
    31681 gcatggcccc aagcatacca ccaccaacaa actcgctaac cttaaaggct agcaggtcat
    31741 tggtgattag ctggatagtc ccagcaacaa tagcctgatg agctagctga ggcaatgaga
    31801 aaagataggc atgccattca accagaagcc ctaaaaacaa gatgataaag ccagcgataa
    31861 ggccatcttt ttgcctgagc cacttgaaga aaaagaggta aaaaaggacc gccaacatca
    31921 agagattggc taagtcgcca accataaagc gaataagatt atataaggta accccaagcg
    31981 cacctaagcg aagcatggca aaaacaagca ataaagcgca ggagaaagaa gcaatcattc
    32041 tcttaatagc cttttgcttt tcaagctctg cctttgttaa acgtctctta gggggatttt
    32101 tttgtcgttg agttcttcta gccatagcct tattataaca ttttttaatc gttatgaaag
    32161 atgacattaa aattctcaat aaatagatga agctgcttga ttttatgcta taatgtcaat
    32221 cataagaaca aataggagtt gaagatggaa aaagaattta acaccttgac ctatggtaag
    32281 cttcccctgc aaattgatat ggggcatggc aagctaattc ccaaaggagt tgaagtcaag
    32341 gctatcgttg atatgcagac cgggcaagtc accttcaagg tttctcagga ggacttagag
    32401 aagcttagaa atagttaaaa aatagacttc gtctcaatgc cctttagctt tattttccaa
    32461 gtcattttat gttaaaataa aagaaattgt tctaaggagt acacatgaaa aaactactat
    32521 cttttggctt aatcggtctt gctttgctta gcttaagtgg ctgtgagtcc attgatcgtg
    32581 ctattaaagg tgatgaatac gtcgatgaaa aaatcgctag agaggaaagc gagacagcag
    32641 caaaggctta tgaagcaaaa atcaaaaaag cactcaaggc tgacgctgat cagtttccac
    32701 aattaaataa agaagtcgac aaagacgaag ctaaggtcat tatcaaaact aatcagggcg
    32761 atatcaccct caagctcttc cccaagtatg caccgcttgc tgttgaaaac tttttaacac
    32821 acgccaagga aggctattac gacaaacttt tgttccatcg ggtgattaat aactttatga
    32881 ttcaaaccgg tgatccaaag ggagatggat ctggcggaga atccatttgg aagggcaagg
    32941 acagcaaaaa agatgcggga caaggctttg ctaatgaaat ctcaccattt ttatataaca
    33001 ttcgaggggc tcttgctatg gcaaatgccg gtgcagatac taatggcagc cagttcttca
    33061 tcaatcaaag caagctcaac caagccaagg ccttatcaat tgataattac tctaagccaa
    33121 tcattgactc ctacgaagaa gggggtaatc ctagcctaga tggtggctat accgtttttg
    33181 gtcaggttat tgagggtatg gatatcgttg ataaaatagc tgccagccca gtcggcccaa
    33241 atgacaaacc aatagagaac atcactatta atgctattga cattgttaag gattactcct
    33301 ttaaaaaata gcctctaagc tacaacaaca ataaaacgac cagctcctta tcggaaaagc
    33361 caccgattca agagctggtc gtgatttttt gctatcaatt aaataaagaa gctagcctat
    33421 tgatcatatc attagcagct atccattcac agccagctat ggtttactag gaatgctttt
    33481 taaagtagcc ctgcttaggc gaaacaaaga agctaatcag aaacaccaca gccgaggtca
    33541 aaacaatgct tgagcctgct gcaatattaa aggtgtagcc caaatagagc cccaacacag
    33601 aggtcatagc tcccaagcat gaggagataa ccagcattac ctttaggctg ttagcataca
    33661 aatacgctgt agccgctggc gtaatcagca tcgccacaat caaaatggta ccaacacttt
    33721 gcatagcagt caccgaaacc aaggtcaaca aaatcatcaa cagataatga taagcagtga
    33781 ccttcattcc catagacctt gctagcacag gatcaaagga ggtaatgagt aattccttaa
    33841 agaagaggac aataatagcc aaaacaaaaa ccgaaacaat gatcgtaatc catttgtcac
    33901 tgtcttgcac tgctaggata tttccaaaga ggatatgaaa aagatccgtt gagctattag
    33961 caatcccaat cagaataacc cctaaggcaa gaaaagagct aaaggttatc cctattgctg
    34021 tgtctccctt gataacagag ttttccttga tgtaggtaat gataacagag gctagcaagc
    34081 caaagacaat agcccctaca aaaaaattaa tccctaaaat aaaggacaag gctactcctg
    34141 gcaaaacagc gtgagaaatc gcatcaccca ttaatgacat ggacctaagg ataataaagc
    34201 agcctactgc tcctgataca ataccaataa caacggctgt aataagggca ttttgtaaaa
    34261 aatgatagga catcaggccc tcaaaaaact tcaaatacat ttaaaacatt ccctttccta
    34321 agaatagatg atcaccatag gcctttgata gggtttcaac agtgaacacc tcatcaacag
    34381 atccataagc gatcagctct ttgttcaata ccactaactc atcaaagtaa tgctctacct
    34441 tgcttaaatc gtgatgaaca attaaaatcg ttttgcctgc ttttttcaag tccttgagca
    34501 ggtcaatgat gattttttca ctaaccgaat caatcccaac aaagggctca tcaagaaaaa
    34561 tatagtctga ctcctgaatc aagcatctag ctactagcat acgctgaaac tgaccaccag
    34621 aaagagattt tatcggacga ttaccaaagc cagcaagccc aacctgctct agcagctggt
    34681 caacctgatc atattctttt tttccgacac gacgaaaaag ccctagccta gtgtaggtcc
    34741 ctaatgagac gcactccttc accgtaattg gaaagttgta gtcaatcatg ctgcgctgct
    34801 ctacataagc aatcgtatgc cccagccttc gaccgtcctt ttgatcaaca gttacttggc
    34861 cactataatc taaaagattg agcatagcct tcatcaaggt tgattttcct gcaccatttg
    34921 gcccgataat cccaacgata gctggtcctt tgatttgtag tgagatattg tctaaggctt
    34981 ttacgttacc gttatagcta accgaaagat tttgcgtatc aatcattttt tctccttaat
    35041 acaaacaaag cacaacacca gaagctgctg tgctttattg ttatattatt ttgctaagcc
    35101 ttcagaaatt ttatcaaggt tccatttcat catggcatag tagctgtctc catcttggcc
    35161 ttttttggct acagagtcag taaagatttc tgcatagatc ggaataccac tgtccttaga
    35221 aacagtctcc attggacgtc tgtcaacact tgactcaaca aaaagcgctg atggcttaac
    35281 gtctttcaat ttttcgatca atgatgaaat ttgatccgga gttccttctt cttcagtgtt
    35341 gatttcccag atgtaggctg atgggacacc gtaagctttt gagaagtatt tgaagcagcc
    35401 ttcacttgtg acgattagct ttttattgtc agcaatagca tcaaattttg attttgcttc
    35461 cttatcaagc ttctctagct tctcaacgta agcttttagg ttgttttcat aggtttcctt
    35521 gtttttaggg tctttagcga tcaattgctt tgcaatattt tttgaataga taaccccatt
    35581 ttcaagattc aaccaagcat gagggtcttc cttgcctttt tcactttcac cttctaggta
    35641 aatcacatca ataccatcag atacagcgaa gtagtccttg tccttttcct tcttagcatt
    35701 ttttacaagc tttgtaaacc aagcctgtcc gccgtcttca aggttaatac cgttatagag
    35761 aataagatcg gcattgctgg tcttctcaac gtcttctggc aatggctcat actcatgcgg
    35821 atcttgacca atcggcacaa tgctgtgcaa gtcaatcttg tcacctgcaa tatttttagt
    35881 catgtcagca ataatggaat tggtaaccac aaccttgagc ttgtcactct tagcttcctt
    35941 gtttccacca ttagagcagg caaccagcat gaaaacagcc aaaaaagcac tcaaggcgag
    36001 gctaagtttc tttttcatca gttatctcct taggatctat tatttaatta attaagtata
    36061 gttaattatg ctattagcat aacttttttt taggcctttg tcaagatttt tatgaaataa
    36121 tctgatataa taatcattat aaataagaga aaggctttta gacatgacgc ctaataaaga
    36181 agactatttg aaatgtattt atgaaatcgg agagcaaaac attaaaattt ctaacaaaat
    36241 ggttgcagag agaatgaagg tttctgcacc cgctgtgtca gaaatgatta agaaaatgat
    36301 cgcacaaggc tggattgtaa aggataagac ctgcggctat tatctaacag agcaagggca
    36361 gcgcttagtg gcaaatcttt atcgtaagca ccgattgatg gaggttttct tgatccatca
    36421 actgggctat actgctagag aggtgcacca agaggctgag gtactagagc atactgtgtc
    36481 agatatgttt attgatcgct tggataaaac ccttggctat cctacttttt gccctcatgg
    36541 agggacaatt ccacgccgcc agcagccact aatcgaaatc aacaaaacaa cgcttaatac
    36601 tattaaagag ctgggaattt ttcgtttgag cagggtgcat gatcactttg agcttatcca
    36661 gtacctagaa gcacaccagc tgacgatcaa tagtgagttt agactgattc aaatagatga
    36721 cttcgcaaaa acctatacca tcacttatgc agataaggaa ttgatcattc ctgaaaacat
    36781 cgccaagcag ctctttgtta ctgctattta aataaaaaaa gacctgatat ttgctgtcac
    36841 cacaggctat caggtttttt tggtcatcat tttttatcag gtaaggcctc taaaaaggct
    36901 atcaagacct tggctgattt ttttccagcc tcaacaataa actgatcgaa ggtcatatta
    36961 gcatcgtggg ccgctgtgtc actcatcgcc ctaacaacaa taaatggctt gccagcagct
    37021 tgagctgcct gtgccactgc tgctccctcc atttccactg ctaaggtctc tgggaaatgt
    37081 gctttgatgg tatcaatact gtcttggccg gcaataaagc tatctcctgt tgcaatcagg
    37141 ccaatccgac tattggtctt ttcctgatca agcacctgct taaaggtctc aaccagcttg
    37201 ctatcactgt caaagtaaag gggctgcgca gccatttgac catagtcata gccaaaggcc
    37261 gtcacgtcca catcatgata caccaagcga tcagcaacaa caacatcacc aatagccaag
    37321 ccactagcta ttgctccagc cgatcctgta tttataatag cgtcagcctg aaaatgctct
    37381 gctagcatcg caactgtcat cgctgacatg acctttccaa caccagattg gactaagacg
    37441 agctcatggc gaccaagacg acctgtatag taggtattgg aaagcacctg atgctcttga
    37501 ctatcgtgga gctgctccaa taaaaaccgc agctcctctt ccatagccgc aataattcca
    37561 attttcatat gatatcctta tttgtttttt tctataaatt aaagaccgca taaaccaaga
    37621 gagcaatcaa gacaagcacc gctaagagaa tcagatttaa ccgcgattga aagcgactgc
    37681 gctttgcatt ttcaattctg cgacttttgt aaatacgatc agtatgctta tcctcaaagg
    37741 tcatgatttt ggtttcaaaa tctgcataat cgtcaggctc aaactgttct ccgcgctgag
    37801 ccttttcgat aatgtcatca gtcagcaagg gcttgcccat tacacatcac ctccaaaatg
    37861 aagggcgtaa tattgcaggg caatgatggt tttagcatcg acaagctttc cttgtgccac
    37921 tagatccata cattcttgat agctcagctc aagaagctca atcacctcat ctgcgtcctg
    37981 tggtctagga ttggcaactc tctgcaggtc tgtcgccaag tacagcttaa ttttttcatt
    38041 acaaaaacca atcgctgtat aaaactcgtg aataagacgc aaatcaccag aataggcggt
    38101 ttcttcctcc agctctcgtg ctgctgcttc taatgctgag ttggcctcac cgacctctag
    38161 ttttccagca ggaatttcat aagaaatcgc ttcgatagcc ttacggtact gcttgacaat
    38221 taacagctta cgctctggcg ttacagccaa tatagcgact gcaccgcgat gaaaaatcaa
    38281 ttcgcgctta gcctgaccta ggccgtttgg caattggaca tcatctaccg caactttgaa
    38341 aatgtgacca tcaaaaatct cttgcctttt aatcgttttt tcttcaaaat ccatgtctga
    38401 tctccttgct ttctctccat cattttactt tgcttgattt gggtgatgtg gcagcctctt
    38461 ggcatagcc
//
LOCUS       DARYJX010000021        38112 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYJX010000021 DARYJX010000000
VERSION     DARYJX010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38112
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(80..1285)
                     /locus_tag="TU257_001043"
     CDS             complement(80..1285)
                     /locus_tag="TU257_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL0834062.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TU257_001044"
     CDS             complement(1538..2791)
                     /locus_tag="TU257_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0834063.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TU257_001045"
     CDS             complement(3188..3808)
                     /locus_tag="TU257_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834064.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TU257_001046"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TU257_001046"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TU257_001047"
     CDS             4121..5347
                     /locus_tag="TU257_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0834065.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TU257_001048"
     CDS             complement(5457..5951)
                     /locus_tag="TU257_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL0834066.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TU257_001049"
     CDS             complement(5948..6730)
                     /locus_tag="TU257_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0834067.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TU257_001050"
     CDS             complement(6829..7368)
                     /locus_tag="TU257_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL0834068.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TU257_001051"
     CDS             complement(7372..7683)
                     /locus_tag="TU257_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834069.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TU257_001052"
     CDS             complement(8070..8207)
                     /locus_tag="TU257_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0834070.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TU257_001053"
     CDS             complement(8591..9835)
                     /locus_tag="TU257_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834071.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TU257_001054"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TU257_001054"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL0834072.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TU257_001055"
     CDS             11812..12657
                     /locus_tag="TU257_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL0834073.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TU257_001056"
     CDS             complement(12853..16815)
                     /locus_tag="TU257_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL0834074.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18767)
                     /locus_tag="TU257_001057"
     CDS             complement(16950..18767)
                     /locus_tag="TU257_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL0834075.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKAADK
                     QQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19127..19600)
                     /gene="perR"
                     /locus_tag="TU257_001058"
     CDS             complement(19127..19600)
                     /gene="perR"
                     /locus_tag="TU257_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL0834076.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19637..20089)
                     /locus_tag="TU257_001059"
     CDS             complement(19637..20089)
                     /locus_tag="TU257_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL0834077.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20329..22971)
                     /gene="polA"
                     /locus_tag="TU257_001060"
     CDS             complement(20329..22971)
                     /gene="polA"
                     /locus_tag="TU257_001060"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL0834078.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23395..25125)
                     /locus_tag="TU257_001061"
     CDS             complement(23395..25125)
                     /locus_tag="TU257_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL0834079.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25143..26339)
                     /locus_tag="TU257_001062"
     CDS             complement(25143..26339)
                     /locus_tag="TU257_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL0834080.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26538..26780)
                     /locus_tag="TU257_001063"
     CDS             complement(26538..26780)
                     /locus_tag="TU257_001063"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834081.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26845..27936)
                     /gene="ulaG"
                     /locus_tag="TU257_001064"
     CDS             complement(26845..27936)
                     /gene="ulaG"
                     /locus_tag="TU257_001064"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL0834082.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28131..29777)
                     /locus_tag="TU257_001065"
     CDS             complement(28131..29777)
                     /locus_tag="TU257_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL0834083.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30081..30797)
                     /locus_tag="TU257_001066"
     CDS             complement(30081..30797)
                     /locus_tag="TU257_001066"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL0834084.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30797..31660)
                     /locus_tag="TU257_001067"
     CDS             complement(30797..31660)
                     /locus_tag="TU257_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL0834085.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31665..32330)
                     /locus_tag="TU257_001068"
     CDS             complement(31665..32330)
                     /locus_tag="TU257_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL0834086.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32425..32910)
                     /locus_tag="TU257_001069"
     CDS             complement(32425..32910)
                     /locus_tag="TU257_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0834087.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33126..33404)
                     /locus_tag="TU257_001070"
     CDS             complement(33126..33404)
                     /locus_tag="TU257_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0834088.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33519..34952)
                     /locus_tag="TU257_001071"
     CDS             complement(33519..34952)
                     /locus_tag="TU257_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0834089.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35435..36055)
                     /locus_tag="TU257_001072"
                     /pseudo
     CDS             complement(35435..36055)
                     /locus_tag="TU257_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36057..36674)
                     /locus_tag="TU257_001073"
     CDS             complement(36057..36674)
                     /locus_tag="TU257_001073"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834090.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36661..37449)
                     /locus_tag="TU257_001074"
     CDS             complement(36661..37449)
                     /locus_tag="TU257_001074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834091.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37520..37921)
                     /locus_tag="TU257_001075"
     CDS             complement(37520..37921)
                     /locus_tag="TU257_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834092.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        11007 a         8919 c         7426 g        10760 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgatcctc tcttgcgctt
     2821 tgtattttgc ctttaaacgc taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc caaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatcg cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tggatccact gggtctaccg gatccactgg gtctaccgga
    17281 tctactgggt ctaccggatc cactgggtct actggatcta ctggatcgac cggtttagca
    17341 accaaggctg ccttggcatc tgagagggat ttcttagcat ttaacacctt aaccaagctg
    17401 ttagtaatag ctgtcggttc tgtctcctga gcataagctg tctcacccgc tgctgcgacc
    17461 tccttagcct tagctagctg gtctgtatag gcttgagcag aagctgctgt atatggagat
    17521 aggtctagat tttctccgat aagagcattt aattggtcta aagcagaacg caattttgcc
    17581 tttccttctt cggcaatcgc agcctttacc tttaaaatag tatcaacaac tgaatttgtt
    17641 tctgtagtgt agcgctctag ctcataaagg gaaatgtctt ttctctcttt atccttgtta
    17701 acagttctat agaaggtacc tgctgcttca atggccttat tgtacaattc cttcaaagac
    17761 tctgatgtca aagcaagatt tggattttct cggtaaagct ctaacagctt agccaaggct
    17821 tgatctaagg cttcatgcgc tacagcagtc ttaagcgtcg taagagcttg cgttaaatca
    17881 gtcgcagcct tatcaacatc tccttgtgaa ggaccaaatg aattttgaag cttagctgcc
    17941 gctgcaagct tttgcacaag accgtcatac gcttctttag gatactcttt gccatctgtt
    18001 ataaaaggtg tagcttgatt aatagcttca tttaaagcat taagattaac aagactagta
    18061 atagcggaat caatagtagt aacagattga tctactgtat tttgatcagg gtcactgttt
    18121 aaataggtct taccaatagt aaccgctgat tgcaaggctt gcagtgattc atcagaatac
    18181 gttccttcag gctggctgag ttttagctta gcctcctcta acgacttcct taactcagtt
    18241 ttattgctgt tggaattttt tagtttaaat gtgaagagct ttttggtatc atttttccca
    18301 tagaataccc aagctttaat agtataagat ccccccggta cagcatatgt aggcgaagct
    18361 aacatttcat cagttaaaaa ggaagtaccc gcagcattgt aaaagtcaaa ccatattttt
    18421 actccagggg tatcaattcc tcttgaacca tctccattcg aaataaagtc aaaagtatct
    18481 ccatcattaa cagtcccatt actaccttta cgagtaaccg taatttgact cataagatct
    18541 gagatagtaa ttggttctcc taattcaact gtatattctt gtggaatatc tatgtgccag
    18601 ttcagatgtt gacctgtccc attattttca aatgcactag cagtagtcgt ttccgcccct
    18661 actgttaaag cgctatcaat attatccgac aaggcaacca atcctgtgct gaaaactaat
    18721 ccaacaagac cacagccctt aagacaccgt ttcgtgaatt tcttcattct tctttttcct
    18781 tttctagagc cctagcaggc tcgaacaata gcaatatgtg tcatagggca gctgctatca
    18841 ctagtagctg ccactttgat attagcctga ttgtgacact caaatatcac ttataattta
    18901 caaaaaattt taagaaaagt caatatacaa acggtttttg ttaaattttt taaaaatata
    18961 acaaaaaaca agcacgccaa tctggtctat aacagttttt attgtcaata gtgatcgcta
    19021 aagggttttt cagccaacaa aaaaagagtg aatccctaac tctctcttct agactttgtg
    19081 ccatatcatc agctacacga acagccaaga tcaaaaaggc cagctctcaa tagtctgtgt
    19141 ccttaccctg cttcgtctga cagctagggc aaacaccata ggctataact ggaatacggg
    19201 tgaccttata gcctgtttgc tggtgtgctt ccttagcgat atccatcaca tctacgtcca
    19261 taaaatcagc gattgtcccg caaacctcac aaaccacatt gacatgctga tgtcccataa
    19321 agtcataata ggtcgtcaaa tcattactaa ttttcagctc ggatacaaag ccctcatcaa
    19381 cgagaacctt caaattatta tacaccgtag caaggctcat attagggtat tgaggctgta
    19441 aatcacgata gattttatct gcgctggggt gctcagtgga ctgaatcatg taagaaatga
    19501 tcgccttacg cgtctcggta atacgaatat gcttgtcacg tagatgctct aggacatttt
    19561 cataggcatt tagagcttgc tgatgtgaat gaatgtccaa gcttacaacc tcctcctttt
    19621 gtaactatgg cactaactag caggaatctt gatcctgctt gctgattagc cgtaaatagt
    19681 caatcttgat acagcgattc ataacaatgt cagctttgcc tgctgatcgc aaaagctcct
    19741 cagcttcttg gctatacaag ccaagctgtg cccaaaagac ctgaccctga caagctaaaa
    19801 agtcctgagc aacctgaggc aaatactcac ttcgtcgaaa gacattggca atatctacct
    19861 taaaaggaat agccgcaagg ctagcataaa cgacctctcc taaaacagac tgacctgcca
    19921 gcctaggatt gacagggaca atccgatagc ccttagcctg cataaaccta gccacatcat
    19981 aagcagcagt ggtttgacga tcagataagc caaccactgc aatggtcttg gaagattcaa
    20041 gataagaggt gatagtctca tcagagggat tttgaaatgt atcaatcatc atttacttcc
    20101 tttttatcaa gcacacccaa tagcaaatca acaacaggaa aagacaatcg ctgccggtat
    20161 gacatagcca accatctggc taccaagctc aaggaaaacc ctccttagca tgacatgccc
    20221 tgctgttttt ttctcttcat tatagcataa gtttttaaaa tgcggaacac aaggaataac
    20281 agcagccaca ccaagcaggc tgccacttaa caccactgct aatctagtct acttggcctc
    20341 ataccagctc ttgccggcac tttcgtctac acgcagcgga actgccaggc tgacagctga
    20401 ttccatcgtt tctttgacca gcgctttaac agccgctagc tcatgattag gcacctcaag
    20461 cacaatctca tcatgcacct gaagcagcat tttggtctca aagccaccag ctactagggc
    20521 ttggtcaaga tttatcatcg caattttgag aatatcggct gcactgcctt gaatgggcga
    20581 attaatggct gtacgctctg caaaggagcg aacgttgaac tgacgagaat tgatatctgg
    20641 caattgacga cggcgcttaa agagcgtctc aacatagccc ttatccttgg cttcacgcac
    20701 aaccctttcc atgtaagcct tgataccagg gtagcgctca aagtaggtgt caatataagc
    20761 cttggcctgt tttcttggaa ttccaaggtt attagacaag ccaaagtcag aaatcccata
    20821 cacaatgcca aagttaacag ccttagcatt ccgacgatca ttggcagtga cgtcctctgg
    20881 cttttcaatg ccaaagacac gcattgccgt tgaggtatgg atatccgctc cctccttaaa
    20941 agcagcaatc aaatgctcat ctcctgaaat atgtgctaaa acacgcaatt caatttgcga
    21001 ataatccgag ctaagcaaaa cagcatcatc atgagatgga gtaaaggcct tacgaatcaa
    21061 gcgcccctgc tccagacgaa tcgggatatt ttgcaggtta ggatcaacac tggaaagtcg
    21121 gcctgtctgg gttaaatcct gtaaatagcg ggtgtggatc ctgccatcag ccatgatgta
    21181 atcctgcagt ccaatcacat aggttgattg cagcttagta atttgacgat agtccaagat
    21241 cttagccacg attggcgcaa ttggcgctaa gcgctccaag acatcaacag ccgttgaata
    21301 gcctgtcttg gttttctttg tcaaatgaag agggagctgc attttctcaa agagtatcac
    21361 tcctagctgc ttgggagaat taatattaaa gacctcacca gccatttcat agatttcctg
    21421 tgtcagttcc tcaatgacca ccttattttg ctctgccatt tcctgcaggc tatcttgatt
    21481 gacagcaatg ccttcgattt ccattttcgc aaggacattg gcaagcggca gttcaatgtc
    21541 agtgtagaga tcagcctgct catgctctgc cagcttatca agcatgactg gtctactatc
    21601 cagcaagacc tgaaccttac gcgccagatg tcctaacaaa acagccttgt caggcacagc
    21661 acgcttgacc cccttaccat agacaacctc atctgtatcc agtgatatag tggtataaag
    21721 acgtgccaga gtagccatct cattgtcctc tacagttgac aagaggtaat tagctaagcg
    21781 ggcatcatag ctggcagccg gcaaatcaag ccccagatga ctaagcagaa ccttactgcg
    21841 cttaaaatca taggtagcaa tcggctgctc aagaaccttt ttaaagagct ttgtagtgag
    21901 gagactaata tctgctgaag cataaatctg gccttggttg ccccaagcaa agccaatcag
    21961 ctcctcgcgg tgataattat ccctcaaagc ttcaaaataa aacaccgtat cgtctgaaaa
    22021 catgtccgct cttatgtcag taacttcctg ataagcaatc tcagctaccg gctcctgtgg
    22081 caactgacta gctaaggcat tttttagttg aacaaaatcc atctcatcat aaaattgtga
    22141 caagcgatct agatctggac cctgatagac aatatcctcc aatccaatcg taatcggagc
    22201 gctagtgttg atagtagcaa gtgtctttga gaggaaggcc tgctccttat catgaagcag
    22261 gttttccttc atttttgaag gcttgaagct atcaatatgc tcgtaaatcc cctccaagct
    22321 tccatattcg tgcaggagct ttagacctgt tttttcccca attttggtca ctcctggaat
    22381 attatcagac ttgtctccca tgagcgcttt caagtcaatg aattgctctg gcgtaagccc
    22441 cattttgtcc ataaggtagg ctggggtaaa ctcttcaaat tcagcaactc cttttttaga
    22501 aatctcaaca acggtatttg catctgtcag ctgaatcaaa tccttgtcac cactgacaat
    22561 agtcacatca aaaggaatct ctgtacgctc tgccatttta tcaagcgttc cgataatatc
    22621 gtctgcctcg taatgctcta gctcataaaa ggcaatacca agcgctccca gcatatcacg
    22681 aatataagga aactgctccc gaaattcatc aggggtcttg gcacgtcctg ccttgtaatc
    22741 agcaaaaagc tctgtccgaa aggttgtttt acccgcgtca aaggccacca agacatgcgt
    22801 cggctgaaca cgcttcatca tgtggtctag catcaaatga aagccataaa tcgcattagt
    22861 gtgaagaccg ctgtgatttt taaagcggtc aatctggtta tagagggcaa aaaaggcacg
    22921 aaaggccact gaggagccat caatcaaaag taatttattc ttgttttcca tgcctttatt
    22981 ataccacaca gtgacctgct ttgctctgac cagctacgct ttttgcaagc actagcaggt
    23041 aaagcagcat acccgtagct tgatcaaaag atccaagctg cttgaaggaa gataaatgac
    23101 tgcttttgct ttatcatcaa gacatttcta ccaaaaaaga gactgagata aaaagagtga
    23161 cactttagag agtcttaact aatatccttt gttatctaat tcattaacaa acgaacaggc
    23221 ctagttttca aaacctcaga aaactaaacc tgttcatttg ttctatttga agtcagactt
    23281 tgtctcaatc tccaaattga tgacatcatc tgctatgact ttcctaagct gatatggacg
    23341 gaaagccttc tgcaaaatcc atgattagtc taggctacat ttgagcgagc ggccttatga
    23401 ctgagtccat ttggccacct tatcagcatg gctagccacc catttcttgg ctgcggcttc
    23461 tggtgtcatg ccctgattga tgtcaagcat aacagcctcc atatcctctt tttcccaatg
    23521 gaagtgatca acaatcctat gaacagctgg caggtcggcc tttaagcccc gacgtgcaat
    23581 ggtattgata ttttcctttg agccaaaggt tttctttgga tctgccaggt atttcaaatc
    23641 gtacttagca aacatccaat gaggagacca agccgtcaca acgatcggct cctttttctt
    23701 gaccgcctga tcaagtgagg tggtcatagc acctgtcgaa gcagcaacga gctcccaatc
    23761 tgccaagttg gaataggcct tttgcgtctt atcagcagca gtcataatac cagctcccgg
    23821 ttcaatccca ataatctgtt gattggcttg atccgaaagc tcctctatgc tgttcacatc
    23881 gctcatatag gctggcacag cgagtcctag ctttgttccc ttcagattag gaccaagatt
    23941 atccagctta tcctgatact tttggtactg ctgctgatgg gtcactggta accaggcact
    24001 tgttgaaaag tctgcatcgc catttgcgat ggtttgccac atcacagcat tatccagtgg
    24061 tgtcaaggtt acctgataac cctcatctct taagacctga gcgataacat gggtagaagc
    24121 cacctcagaa tcccactgca cataagcaat ggtcaccttc tgccccttgt ctgctgagct
    24181 tgataacatc gcagcaaagc cacgccccaa agctgacaac aaaaagacag ctaaagcagc
    24241 tagaccaagc catttcttgg tttttccagt ctgcgttctt tcttgcggct taccgttaaa
    24301 atgctgagtc atacgatcca aaataatcgc caagataaca agggccaaac cactaacaaa
    24361 gccacgccca atatcagcat gctgcaaggc cgataggacc tcacgtccaa gacctggagc
    24421 accaatcatt gagcctgtca caaccattga tagggccaac atcatggtct gattaacacc
    24481 tgccatcatc gtatgctttg ccaagggtaa ttcgaccttc agtaattttt gtttaggggt
    24541 tgacccaaag gcatctgaag cttcaaccaa ttctgtcgga atatgacgaa gcgctaaatt
    24601 ggtaaaacga acagtcggcg gcaaggcaaa gataaccgac gcaaagacgc cagggaccat
    24661 accaatgcca aaaaaggcga cagccggaat caaataaaca aaggctggca tggtctgcat
    24721 aaggtccagc attggattaa tcacctggtg aacaatctta tttttagcca tccaaatgcc
    24781 caagggaata ccaagcaaga cagagatgag gcttgctacc aaaaccagcg taaaggtatt
    24841 gatcagctct gcccacaggc cttggttata gacaaataac aggcccagga gggtaaagat
    24901 cggcaaaggc catttttttc ttgccaagaa aaacatcgca caggtaacca atagcataaa
    24961 cagtaacgga ttgataaaca aaagggtctg cgtgatccaa tccatcaaag cattgcccac
    25021 aagctgcagc agatcaaaga agcctgaaaa ggtttttgtc agccactcag ttagttgctc
    25081 aaccagctgt gccactggta gagttgtttg taataggttt tccaaaatac agtctctcca
    25141 ttctaattaa ggtcgtcatc tggaatatta gccaaggctt caaggacacg cccacgaata
    25201 ataaccccta acaagcggtg ctgctcatct gtcactgcaa ttggcgcaga agagtcataa
    25261 atcaagggca aaatatccgt aataacagta tcctttgaga ccgttctgac attacgatca
    25321 ataacctctg acaaggggag ctttttctga cgtgcttcaa tcgctccgtc tgctgttagg
    25381 cttcctatta gctgacgacg acgattggtt gccatgagca tagacacctc ctcattgtgc
    25441 atacgattca aagccacctg cggaccgtcc agatcaaccg ttgttgtgat aggcttaatc
    25501 ataatatgct gagcagtcag cacctttgag cggtcaacgt cctctacaaa ttcacgaaca
    25561 aaatcattag ccggattggt tagaatatcc tcacccgtcc caatctgcat gatctgaccg
    25621 tccttcatca aggcaatacg atcaccaata cgcagagcct cattcaagtc gtgactgata
    25681 aaaataatgg tctgcttcat cgtctcctgt aattctagca gctcatcttg catgtcacga
    25741 cgaatcaagg gatctaaggc agaaaaagcc tcgtccatca gcaaaatctt agggctgttt
    25801 gccaaggcac gcgccaagcc aacacgctgc tgcatgccac cagacaattg atcagggtat
    25861 tggtccctga cctcaagaag ccctgactga tcaagcgcac gctttgcaat ctctcgacgc
    25921 tcctgctttg gtaccccacg cagctccaag ccaaactctg tgttttccaa aatcgtcttg
    25981 tgtggaaaaa gagcaaagct ttgaaaaacc atattcatat catgcctgcg aacttctctg
    26041 agctgatcca cagacagttt agaaatatcc cttccctcta ataaaataga gcctgctgag
    26101 ggctcaatta atcgattaag catacgaaca agcgttgatt tgccgctgcc tgaaaggccc
    26161 atgatcacaa aaatctcgcc ttcctgaacc tcaaagctgg catcatagac cccgacagta
    26221 actcctgtct ttttaaaaat agcgctctta cttttaccag ccttgatcat ttcaagagct
    26281 gctttttgtt ttttgccaaa caatttactc aaatgcctga cctctaaaat agttcccatt
    26341 cttttcctct cttgttctct tcctcgatta aagctaaatt agcttaatag atttctaaaa
    26401 gtgccaccac aattttaaaa taatgaggtc actttttgct taaaaaaaga gtctgcctaa
    26461 acagaacaca ttaattatat aatatatggt cactttttgt caagctggac gcttgctacc
    26521 caagtatcag gatcgtccta agcagtgata tcactagtca accaagcact taacagccct
    26581 gaacagacca cagcaagcag gcctttctga cacttagcgc cttgagagct tacccagcag
    26641 cctcctctag ctgacttgat tgacctatct gactcttgtc ctgcaaccaa accaatgctt
    26701 agactgccaa gcaagctccc aatagcaata agatctgcta agcaaagcgt tagcttgctt
    26761 tgaccatagc tgctagtcat gtctaatagc actctagata aatcaaaagc cccacctagc
    26821 aaggctagat gaggcaaaat aggtttagag aagggcttta aactgaatat ttgagtcttc
    26881 caagaagcag tcgtcaaagc cacgtgggtg atgatactcg atgcgatcct gatcctgtgg
    26941 ataggtgtat ttgccaccaa cctcccaaat gaatggatgg aattggtatt gcaagcgctc
    27001 cttacgcatc ttccaaagct ctaggatttc atcagttgag gccatgaagt ttgaccagat
    27061 atcatagtga accggaatga caaccttggc gcggagattt tctgccatac gaagtaggtc
    27121 aacagaggtc atcttatcct gaataccgat tggattttca ccataattgt tcaagacaac
    27181 atcaatatcg tagtcacgtc catgcttagc aaaatagttt gagaagtggg agtctgcacc
    27241 atgatagatg gttcctcctg gtgtttcaaa aatgtagtta acggttttgc gagctaactc
    27301 ttcgtcagtc actggaagtc ctgctagctc gccaccattt tcctcagcgc cagcaactgg
    27361 taaggtaacg atacaggtac ggtcaaagga ttcaacagca gtaaccttga tatccttgaa
    27421 tgcaaagcta tcgcctggtt ttaccacgat gatacgatcc tttggaacac cccagctctc
    27481 ccaaatcttg ccgcactcat aagggccaac aaatttgaca tggtcaagct ttggattgtt
    27541 gataatggct gctgcagtat tgatatcaat gtggtcacta tgataatgag acaccaagta
    27601 atagtctaac tcattaatca taaagggatc aataaccatt ggctgagctc ttagatttgg
    27661 ttgtagcttg cgaacccctg ccatattggc catttggtga ccacgaacca tgtcttttac
    27721 ttttttagtt gcctttccac gattggacca taggtccatg acaacattgg caccacccgg
    27781 tgttttgatc cagataccgc agttacctag ccaccacata gagaaatttc cttcaggcac
    27841 tacctcttct tcaatttctt cgtttagcca ggttccccat tctgggaagg tgctaagaat
    27901 ccatgattca cgagttatat cttgtacttt agccattatg tttcctccaa aatgaatttt
    27961 tatctatact ctaagtatag accttcttta ttctcataaa aagaccaagt gtcacacact
    28021 cttgtgttca aaactggact gaattttggc tcaaaataaa ctaaaagccc cagccttctc
    28081 ctaaaccaat agacagctga ggggtcctta tcaataggca agctagtagc ttacaataat
    28141 tcgtgatgaa tgagcttttc aatttttgtt ttcaaggcat agcggtcagc atcgtcctta
    28201 acaatggtct cgatcgcctt ttctagctca agggaaaaac gagagctatc actcaagcgc
    28261 ccctgctttg aaaaacggat caatctaata atgtcatcat cgctcaaaat aggattgaca
    28321 atcagtacgg gaacaagagc ctccagtgcg tctgttgttg ataccacaat gtcaacagac
    28381 atcaaatcaa agacactctg gtattgctct gttgtaaaga cagcctcgat ttgacaattg
    28441 ggcaaataac gctggcactg cttcaacagc agcttttgaa tcccaatgcc atcatctgaa
    28501 acgataacaa gcttggtctt gtcccagtca gcatgactat ggcgcagctc tcctcccaga
    28561 tgaatcgtta gataagccac gtcatcatct gttagacgga tctgccaagc ctgctctagg
    28621 attacagcac aggattgagc catagcaaag agctcctcgt atttttcctt aatatggtct
    28681 gttaaaggat tgatcgaaaa aatcccatag gcctttcgat aaacaagggc cttgcaatgc
    28741 ctggtcagct gtctaagcaa gtcctttttg tgggtaaaat gcagctgata gcgcagctcc
    28801 agctgatcga taaaatcacc aatagtggct cgcatctgct cataatcctg actttcaaca
    28861 tggtgatcct gatcttttct aaaggatagc atcagcatgg ctatcatgcc tacctcaatg
    28921 tcatctaaat gcagcttgaa attgtggtaa agctcactag ccaatgcctt agcaatctgg
    28981 tattccttgc gcttccaaat caggttaaaa tcccttttaa gcgctgtttt agtttccgaa
    29041 tgcaattgca tgttgcgata gctaagcagg ataaaaggaa gaatttgcag cataaactga
    29101 ctatcctgaa tattaattgt tttgcctagg ctagcctgag acaaaaagag gtattcgtga
    29161 aaataatcca aaacctcctt tgaaaaataa gctgacaagc cttgtgtctc agaaagctta
    29221 tgatcaaaaa gctcaataaa gctgctattg cctccctgat aaacacctgc caataccttg
    29281 taaaggtact gaatcaaagc catagggtga cagtcaaagt aatagccctt ggccttggtg
    29341 gcatgcagct gaatcttatt gttatagcta gacaattcct ctctcagttc agcaaggtca
    29401 tttaagatgg tatttctgga aacatcatta atcatcatga gcttatccag tgtcacccgc
    29461 tctgttgcca ctgcaatata aatcgctgat aagctcctgc gctcatcacc cttcatgaca
    29521 tagtgataat ctgccacttc attgaggagc tgttggcagg cagccttttg ctcactattt
    29581 agcaagatgc caacccgagg ataggagaca atttgagcaa catggctggg cagcgcttcg
    29641 ttaattttat ccaaatgata atagattttg cgccgcgact gacccaaggc agctgaaatc
    29701 gccatgactg tctcagcctc cttcaatcga atcagatatg acagcagatc atagcttttt
    29761 ttatccaaaa taatcacgtt catacctccc ttctataaaa catcactacc acacagcctt
    29821 atcagtttac cattttacct atctgtagga aagaatacta ggccaaagtc aatttctaaa
    29881 taggaaaaaa cgaacgatca ttagttttct gaagataaaa ttcctaatta gttcgctttt
    29941 ttcttttata attgtaatag ttgaattaat tattaaactt tgtctaaaat aagaggcttt
    30001 ttatcccaga ttgcaacaag ggttaacacc ttgaccttaa gcctagctaa gcagctctca
    30061 ctaagttact agctgctgcc ttaatgccgg ctaccttttt ggccataata ggcatttgga
    30121 ccatgctttc taaggtaatg cttgtccata atataggttg gagctggctc cacacgagga
    30181 ttgatttgtt ctgtcaggcg gttcatcttg gccacctctt cgagcaccac tgagtgataa
    30241 accgctaatt caggcgtctt gccccaagta aagggaccat gattgcgaac aacaatacca
    30301 ggcactgcca tcggatcaag accacgacta gcaaattcct ctaaaataac cgtacccgtt
    30361 tctttttcat aggctccatt aacctcatcg gcagttagag agcgagcaca tggaatgggg
    30421 ccataaaagt aatcagcatg agttgtccca taaaatggaa tatctcgccc agcctgtgcc
    30481 cagccaaccg cttctgttga gtgtgtgtgc acaatcccgc caacctctgg ccatgccttg
    30541 tataattgca catgggttgg caaatcagaa gaagggttca gctctccctc aacaatagtg
    30601 ccatctaagt ctgtaacgac catattttcc ggtgttaatt ggtcatagtc aacgccgctt
    30661 ggcttgatga cgatacgtcc cagctcacga cagacctctg agacattgcc ccaggtaaat
    30721 ttcaccagcc catgcagcgg tagggccttg ttggctgcac agacacgttc acgcatttct
    30781 tgtagccttt ttgccattag cttaaccccg ctttctcaat cagtggataa aggaaatcct
    30841 gtgcctcctt gatggcagct cttgtctcct ctacagtttc acagttttct gaccacattt
    30901 caatcaaaaa tggaccatga taatgcgttt tcttgagcac atcaaacatt gcttcccaat
    30961 caacacagcc ttgaccgaat ggcacatcac gaaattgccc tttagatgtt tctgtcacag
    31021 cataggtgtc ctttagatgc aaggcagcaa tagaccgatg cccattgtaa aattcactcc
    31081 agaggtcatt atgccaagca gagacattgc ccgtatctgg atagacaaag agataagggg
    31141 agtcaatttc tttttccaca gctaggtatt tctcaattga gttgataaaa ggatcgtcca
    31201 ttatttcaat ggctaaaata acctgagctt cctctgccca agtgcaggcc tgtctgagat
    31261 ttttgataaa gcgcgcacgc gtttcaggtg atttttcttc ataataaacg tcatagccag
    31321 ccaattgaat ggtacgcaca ccaagatcct gtgctagcac aatgcatttt ttcattagct
    31381 ctaatgatgt cgcttctgtt tctggattgc tagagccaag tggataacga cgatgaccag
    31441 agaagcaaat gcttgggata cgaacccctg tttcataaat agccttgaca atgtctagtc
    31501 gctcctgttt actccaatcc aagcgcgcta ggcgagcatc tgattcatcg acagacattt
    31561 ctacaaaatc aaagcctaat acctttgcaa attgcaagcg ttccagccaa gtaaaatgct
    31621 ttggcgttgc tttttcatat ataccaatag gacgcgccat attgttaccc ccaaatgcgt
    31681 cgaatctcgt ctttaaaggc acgtgccgct gctgcaggat cctctgcttc agtgatacca
    31741 cgacctgcaa taaaggtaaa gacattaacc ccttcaaaga gcttgagggt attgatatct
    31801 aagccacccg tcaccgatac acgaaagccc atgtcaatga gggctttgac cttgttcaga
    31861 tctttttcac cccatacttc accagcgagt agggcgtcac gtgattgatg gtaaatcgcc
    31921 tgtgaaatgc ctgcatctag ccacaattgt gcctgttcat aggtccaatc accatacagc
    31981 tcaacctgaa tctcgccacg ttccccacgc tcttctttga tggctttcag tgcggctgcc
    32041 atggttggaa tagtggcaca gcaaatacaa gtcatccagt ccgcaccacg cttagcatta
    32101 ttcttagcaa cagtaccgcc agcgtctgca cacttggtgt ctgctacgat gatcttctct
    32161 ggaaataagc tacgcagcac ctcaaccaat tcgctgccta cttgaagcag gcaaactgtc
    32221 cctgcttcga ttacatcaac ctcgtgacca actgcaacag cagccctgac cgccccctgc
    32281 aaatcagaat gatctaaggc aacctgtaat tttggaatat gtgtcatgat tttctaccaa
    32341 gagcccgtag caccgccttc aatgcttaat agcgagctcc tatcctttct gttgtgtttg
    32401 attcgtttag tgatgatggc ttgtctaaga atccaaatcc aagccctcta aataaggact
    32461 atttttggac tcgtccacca aagccaaaac ctctgctgga gtgtgacagg caactaagcg
    32521 cgaaatagcg tcttccagtt caaaaagggc gacaatctgt ggaatagcaa ctgttgtatg
    32581 aatagaagga tcagttgccg ccaaggttag caataccgaa gcctctttgc catctgaaaa
    32641 ggtcaccggc ttggtcagtg tgataagagc aaaggcattt cgcttgaccc ctacaccagc
    32701 ctctgcgtgt ggcatggcca ttcccggcat aaggacataa tagggcccgt acttttctgt
    32761 tgatgcgata atagcgtcat aatattcaga ggtcaccgcc ccgctgtcaa tcaaaggctg
    32821 aacagctagc ttaaccgctt cctgccagct agctgctgac aagcccaagc gaatagagtt
    32881 gttttcgata aatgcttttt ttaaattcat ataactatcc tttctaaatc aaattctttg
    32941 gccagacact ttttgcctca ctcctatcta gctgataaag agaaagagct ggaatctctc
    33001 ttcacaactc tcactccatc tatccttact gaaagttgat tgctacagct tagcttacag
    33061 ccaagtggct gctcttaggc tcactatcat ttgccatgag cagcactgat gtcatcaggg
    33121 ccgctctaaa gcaccgcctg tagcttggtt ttgatttcat tgtcgtccat aagattatct
    33181 agtccaacca aatgaccctt tgtacgccca tctaattcat gaatcaggtg attagaagca
    33241 accacaatat catagcctga ggcaagtccc tttgcctcac ccactgagca agaagcagac
    33301 tgaatatcag tcaccccaag ctgacgaagt gcgttttcaa ccttcatttt aataaccatt
    33361 gatgacccca tgccattacc gcatgctgta agaaccttaa ccatttattt tcctccgaat
    33421 atatgataat ttgatatgaa tgaagacctg cagaagtata tcgacaaact cctaccagcc
    33481 tgtgctaaaa gacgaataag cagctattat caccttgctt attgtgcttc accgcggtag
    33541 taagcctctt tatccttagc cctagcaaat tgtagctgtg gaatagcaag taagaagaca
    33601 cacaccacca catagcctgc aataccaagg aacttgaaga gataaccaaa tggaagccaa
    33661 ggaagcacca ggtcaatatt gccatgataa ccacctgtca agcccaacag accaactgcc
    33721 actgcaccta aggcaacctg aagaatacct gatataaagg atagagcaac agctgccttc
    33781 cagccaccac gcttatctgc ataaacagca atcgcagcat tatcaaagaa gaccggaaca
    33841 aatcctgtga tgatcaagat tggattttta aagatcacaa gaagtgcaat agtgattagc
    33901 tgaccgataa gcccaaaggt aaatcctgac aaaacagcgt ttgaagagcc aaagccatat
    33961 gacgctgcaa cgtccaccgc aggaaatgaa cccggaagga gcttacttga aatcccttgg
    34021 aaggcattgg tcaactctga cacaaacata cgcacaccct gcatcaggat aaagagataa
    34081 actgagaaag ttaaggaggt ttgcaaaata tacataaaga aggcctgctt agctggatta
    34141 aaggcaccag cacctataag ttctgcatta gacatcatat ctgggccaag cacagccaag
    34201 atagcaccaa agaaaaccag cattagagtg gcagaagcaa ccaccgtatc atgaaaaatc
    34261 gttaaaaagc ttgctagctt aagattgtca aggttctctt cttttttacc aaagaaaggc
    34321 gccaccttgt caacaaacca gatcgcaaac tgctgctggt gcccaatggc aaagcctcca
    34381 ccacctgtca agcgctgagt cgcctcaact gtcatattgg agctgacagc ccagtaaagg
    34441 ccacagataa taccgaccgc ccaagcacca aaagcatttt gaagctgagg gattaaaaga
    34501 agaacaaaca cagagatggt tgccgcctgc tgcaccatga tatgacccgt aataaagagc
    34561 gtacgaacct ttgtcacctt acgaagcgcc actagcaaaa tattgacccc aaaaccgatc
    34621 aaaagggctg tggtggcaac gctgatggat cccatctcct ctagcttggt attggctgct
    34681 gcaagtccaa agtaagggtc aataactgcg gcctttaatt caaatttctt acccaatgcc
    34741 actaggattg ggcgaaaggt gttaaccaag cccccagcac caacattcaa aatcagataa
    34801 ccaaccgttg ccttaacaaa gccagcaaat acttcatgca ggggcttttt aagcagcaaa
    34861 tacccaatca aaaccaaaag acctacaaag aaagccggat tttgcaaaat atcttgcgaa
    34921 aaccagttta ggggagctat aagcattttc ataagaacta cctcttttca cagttaataa
    34981 atatgatatt ttctatacaa taattgtaaa cgatgtaagc gtttaaaaaa aagaccaaca
    35041 atcacacaaa gaagtgttca aaaatgtact gaagccaatt tccagctagc tctgatcact
    35101 gttaaagcac tatcattaat ctctaattaa taaccaaaca catcacaaca atatcgggct
    35161 aacacaaaaa taggccagcc catactgccc agccaaaacg aaacaagcaa tcaattcaag
    35221 gcacttaacc ctgttttata tcgtacaaag cccttttaag atgattttgt ttgtttccta
    35281 atcgtaaatt agttatctga tccgttctct cctcagatat actcaccctt atctaattct
    35341 actgtcaaat agctacttac tcataagcaa atgaatatta agcaaccacc aagctacaat
    35401 aaaagacctt accctgttgg caagatctta ttcattatac aatttttcct tctgcgacat
    35461 ggactacctc atcacacaag tcttcaatat ctgtcttcag atgtgagctt aaaatcacaa
    35521 gcccattttt gctaacatct aaaagcaatt ttttcgtttg ctccacgctc ctgtcatcta
    35581 atgcattcat tggctcatct aatataagga tcttagggtg atgcatcaag gcctgaatta
    35641 accctaattt tttcttagtg cctagcgatt aatgcttaaa tgctgtttga ctaaactgat
    35701 gtaaatgata aacatctaac caaaaagcta aatcaatatc tctagcctta ggagagattg
    35761 acctaagcaa ctctagattt tgtaacaatg ttaaatgtgc aataaactct ggattctcaa
    35821 tcaaaatccc agcatcctcg atataattat ggtactgtct aattttttta ttgtcctgat
    35881 aaacagctcc ttcatctaat ttgatataac cagctaaggc cttaagtatc aaggtttttc
    35941 ccgaaccatt aatacctacc aaaccataga tattaccttc tttaaaagta agattaatat
    36001 catctagaac aaggttaccc ttatacagtt ttctaccatg ttcaatccgt aacatctcag
    36061 ctctccttat aataattgtc ataaagcata tgtaccaata ctattagcag caggcaccac
    36121 caaacatcaa acaaaaagta acgtatcaag gtgagactag caaacaagat catagctact
    36181 acagcagatg aggcatagcg tatcataaca taaatcaagc aaatatctat agtaagccaa
    36241 gataccataa gataacatag tcgttcaata tgatatggtg caccataata ggtcatcaat
    36301 acacctaata ttaaaacgat aaaaagtaac cactctttaa tatagaaaat cgtactcgtc
    36361 cgccatagct tgttaaaaaa taccaactga cttcgagcat gaaaacgaaa gatttcctta
    36421 gttccttcag ccaaatccgc caaaaatgaa atcgtaaaat aaaagctgtt gaaggacaag
    36481 cctagcaagg tgataacctt gacaaaatca gctgtctccc cttcaatcac tggaaacggc
    36541 attagcaacc gatagcacac taaattatga aaatctcgct ccccagtcat attagcctta
    36601 atcaataaaa gatgtattag taagccagta agacatgctt tcattccaac aaccagcagg
    36661 ttagataatt tcatggtgct tcctcaattt taaaacgatg cacacaccca ctaagcctaa
    36721 ataaggtgat aaaaggtaag gaatatcagc atcactataa gatgttgaca tcaaagaagt
    36781 cataagaaca tatttgggag gtaaatagct atataacaac ggtgacaaag cccacatcaa
    36841 aatcaaatag agcatgcttg acttaataaa ggattgaaga tagtcaacaa gaaaacaaac
    36901 gaaatacgta tgaacgaaca aagctaacga ttttactaag caatagtaag ctataaaggt
    36961 tgttgctcct tgaccaaaaa aacgcaatat tgagttttga tcaaaataag gcattaaatt
    37021 accgttcata tgggcaacac catttagcca agacactaaa gtcaaagcaa atattacaat
    37081 gtaaaaactc agtaaaacat ataagctcaa ctgaagcttt aaaaaaatac accttttacc
    37141 atagtcagac tttctgccaa tgaggtattt aagatgtctt gacttaaggt aatagtaggc
    37201 ataggccact aaaatcatca ctagtggata gataaaagat tgataaaaac taaaatcaaa
    37261 caccacacta tccaaacgta tcatactcaa caatagactt ttctttacct caattccacc
    37321 agataaatct actgcacttg tatcaaaaaa taagatatgc ttcaaactgt caaaataaat
    37381 aaaacctaaa aatagtaacg ggactaatgg ataaaaatag cgaaatggaa ataatctata
    37441 ctgtagcatt tatgaataac tcccctacaa aaaatcaagg aaacgcctcg ttactaactc
    37501 aattcacaat tgtagatatt taccaattgt ctggagacca actaccacta atggttgttg
    37561 ctccgtccca ccaattttca cgtaccagat gcaaggcata aaggtaccca cttttagtat
    37621 cctgtgtata aattcctctg tcgcctgtcc aagttttatc tatatcactt cttctttgac
    37681 cgttactatt agctagatag tgccttacca caatttctct attacgtcct cttgaatcta
    37741 aattaacgac ataataaggc gccgcactct tcacaagata atctttcgtc cttccaaaag
    37801 atgacgtgat tctaaaattt tgcaagtaac caatttgtcg ttctgctata actaaagaac
    37861 taatcaataa tgtagaagct acaattgcca ataatccaat cttaattttg cctaatttta
    37921 ttttttaata atttataatt tttatatatt tagcacatca tcagcgcttc cttgacaatt
    37981 gataatacaa ttcatgctag gcttaatcga taaaactaaa tactagatag taatcaacac
    38041 cagtaaacca agattgtaaa ccctttcttt ttcgtttata ttttaacatt aatattattt
    38101 ttggtcaata ac
//
LOCUS       DARYJX010000022        35713 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYJX010000022 DARYJX010000000
VERSION     DARYJX010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35713
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..693
                     /locus_tag="TU257_001076"
     CDS             <1..693
                     /locus_tag="TU257_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834093.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TU257_001077"
     CDS             complement(1204..2832)
                     /locus_tag="TU257_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834094.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TU257_001078"
     CDS             complement(2837..3568)
                     /locus_tag="TU257_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834095.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TU257_001079"
     CDS             complement(3605..3862)
                     /locus_tag="TU257_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0834096.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4233..5681
                     /locus_tag="TU257_001080"
     CDS             4233..5681
                     /locus_tag="TU257_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834097.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQGPRGEKGEQG
                     QRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGENGEQQPKGD
                     QGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSKKAVL
                     PATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5863..7851)
                     /gene="tkt"
                     /locus_tag="TU257_001081"
     CDS             complement(5863..7851)
                     /gene="tkt"
                     /locus_tag="TU257_001081"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0834098.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8235..8879)
                     /gene="fsa"
                     /locus_tag="TU257_001082"
     CDS             complement(8235..8879)
                     /gene="fsa"
                     /locus_tag="TU257_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0834099.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9053..10558)
                     /gene="glpK"
                     /locus_tag="TU257_001083"
     CDS             complement(9053..10558)
                     /gene="glpK"
                     /locus_tag="TU257_001083"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL0834100.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10898..11491)
                     /locus_tag="TU257_001084"
     CDS             complement(10898..11491)
                     /locus_tag="TU257_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL0834101.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12159..12359)
                     /locus_tag="TU257_001085"
     CDS             complement(12159..12359)
                     /locus_tag="TU257_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0834102.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12418..12573)
                     /locus_tag="TU257_001086"
     CDS             complement(12418..12573)
                     /locus_tag="TU257_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0834103.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13079..13945)
                     /gene="rsmI"
                     /locus_tag="TU257_001087"
     CDS             complement(13079..13945)
                     /gene="rsmI"
                     /locus_tag="TU257_001087"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL0834104.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13950..14273)
                     /gene="yabA"
                     /locus_tag="TU257_001088"
     CDS             complement(13950..14273)
                     /gene="yabA"
                     /locus_tag="TU257_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL0834105.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14266..15066)
                     /locus_tag="TU257_001089"
     CDS             complement(14266..15066)
                     /locus_tag="TU257_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0834106.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15063..15938)
                     /locus_tag="TU257_001090"
     CDS             complement(15063..15938)
                     /locus_tag="TU257_001090"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL0834107.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15952..16587)
                     /locus_tag="TU257_001091"
     CDS             complement(15952..16587)
                     /locus_tag="TU257_001091"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL0834108.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16903..17187)
                     /locus_tag="TU257_001092"
     CDS             complement(16903..17187)
                     /locus_tag="TU257_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL0834109.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17188..17634)
                     /locus_tag="TU257_001093"
     CDS             complement(17188..17634)
                     /locus_tag="TU257_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0834110.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17739..18329)
                     /locus_tag="TU257_001094"
     CDS             complement(17739..18329)
                     /locus_tag="TU257_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL0834111.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18560..19189)
                     /gene="upp"
                     /locus_tag="TU257_001095"
     CDS             complement(18560..19189)
                     /gene="upp"
                     /locus_tag="TU257_001095"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL0834112.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19339..20970)
                     /locus_tag="TU257_001096"
     CDS             complement(19339..20970)
                     /locus_tag="TU257_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL0834113.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAG
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21056..22501
                     /locus_tag="TU257_001097"
     CDS             21056..22501
                     /locus_tag="TU257_001097"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL0834114.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22761..23540
                     /locus_tag="TU257_001098"
     CDS             22761..23540
                     /locus_tag="TU257_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834115.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23565..24503
                     /locus_tag="TU257_001099"
     CDS             23565..24503
                     /locus_tag="TU257_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0834116.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24513..25538
                     /locus_tag="TU257_001100"
     CDS             24513..25538
                     /locus_tag="TU257_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0834117.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25535..26533
                     /locus_tag="TU257_001101"
     CDS             25535..26533
                     /locus_tag="TU257_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0834118.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26638..27291)
                     /locus_tag="TU257_001102"
     CDS             complement(26638..27291)
                     /locus_tag="TU257_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL0834119.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27358..28293)
                     /locus_tag="TU257_001103"
     CDS             complement(27358..28293)
                     /locus_tag="TU257_001103"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL0834120.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28793..29584)
                     /gene="pflA"
                     /locus_tag="TU257_001104"
     CDS             complement(28793..29584)
                     /gene="pflA"
                     /locus_tag="TU257_001104"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL0834121.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29661..30995)
                     /locus_tag="TU257_001105"
     CDS             complement(29661..30995)
                     /locus_tag="TU257_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL0834122.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31123..31680)
                     /locus_tag="TU257_001106"
     CDS             complement(31123..31680)
                     /locus_tag="TU257_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0834123.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31690..32475)
                     /locus_tag="TU257_001107"
     CDS             complement(31690..32475)
                     /locus_tag="TU257_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL0834124.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32488..33411)
                     /locus_tag="TU257_001108"
     CDS             complement(32488..33411)
                     /locus_tag="TU257_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL0834125.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33602..34252)
                     /locus_tag="TU257_001109"
     CDS             complement(33602..34252)
                     /locus_tag="TU257_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL0834126.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34242..34820)
                     /locus_tag="TU257_001110"
     CDS             complement(34242..34820)
                     /locus_tag="TU257_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0834127.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34893..35018)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
BASE COUNT        10494 a         8496 c         7080 g         9643 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaacgaaact acggagacaa actaatcagc
     4141 agctatttct tacatttagc tagcgtgtta agatagctat tggaaaagat ttttaggaat
     4201 acttcatatt tctatcatca aaggagagag aaatgataaa taaaagaaag aaaaaactta
     4261 tctacaggta tggtgtctgc tcggcagcag ttatcctagc agcgcttgct agcctaggaa
     4321 catgtaaaga agcaaaagca ttatctggtc cgccaggata cccacttact cgtgatttct
     4381 cccgtaactt cctagaagaa aatactgcaa aatatttaga tcaattaaga gaacatctac
     4441 agcacagatt tagtgaactt gagagcttaa caagaaaatt agagaaagaa ggcggtaccc
     4501 gaggtccagc agggcctccg gggccagccg gacctaaagg ggaacgtggc gaaccagggc
     4561 ctgttggacc tatgggacct agaggtgaac aaggtcctaa aggcttagac ggagcacgtg
     4621 ggcccgaggg acagcaagga aaacctggac ctgtcggacc tcaagggccg gcaggtccag
     4681 cggggcaaaa aggggaaacc ggacctcagg gacctcgtgg agataagggc gatactggag
     4741 aaactggaaa gcaaggacca gcaggagaac gtgggccagc tggacctcag ggaccgcgcg
     4801 gagacaaggg tgaaaacggt gcacccggtg agcaaggccc tattggtcca aaaggtgaga
     4861 ctggacctaa aggtgacaag ggagaacgcg gcgaaaaggg cgaccaaggt caacgtggtg
     4921 aaaagggcga ccaaggtcaa cgtggtgaaa agggcgacca aggtcaacgc ggtgaaaaag
     4981 gcgagcaagg ccaacgtggt gaaaagggcg agcaaggcca acgtggtgaa aagggcgagc
     5041 aagggccacg cggtgaaaaa ggcgagcaag ggccacgcgg tgaaaaaggc gaccaaggtc
     5101 aacgtggtga aaagggcgac caaggtcaac gcggtgaaaa aggcgagcaa ggccaacgtg
     5161 gtgaaaaggg cgagcaaggg ccacgcggtg aaaaaggcga gcaagggcca cgcggtgaaa
     5221 aaggcgagca aggtcaacgc ggcgaaaaag gcgaccaagg tcagcgcggt gaaaaaggcg
     5281 accaaggtca acgtggcgaa aaaggcgacc aaggtcaacg cggtgaaaaa ggcgaccaag
     5341 gtcaacgtgg cgaaaaaggc gagcaaggtc aacgcggtga aaatggtgag caacagccaa
     5401 agggtgacca aggaaaggat accaagccat cagttccaaa ggcaccagaa tcaccaaaaa
     5461 tgccagagaa gccacaggct cctgaaaagg ctcctgcacc gaaagctcca aaggcttcag
     5521 agcagtcagc tagccctaag gcaccagcac ctcagtcaac accaagcaaa aaagcagtcc
     5581 taccagctac aggagaggca agccatccat tctttagtct ggcagctctt agcgtcatcg
     5641 ctagcgcagg tctgctaacc ctaaaaagaa agaaaagcta agccagctat ttgacaatag
     5701 cttctagcaa ctcgggatag atctgcaagg ctgagcagta gcactattaa atctgaaaca
     5761 aaaacgcatg acgtcctccc taaaaagggt tgaacatcat gcgttttttt gtctaataat
     5821 gccgaaagca agcctagata aggcctgctc cagcttaatc acttatgata aggatttgta
     5881 caattcagta gcatgctcta ctgtaaagcc atattcttca aagatacgat tgcccggtgc
     5941 agaagctccc catgtatcaa tggtcagtgt tttccctgca aggccaacgt attttgccca
     6001 gccaaagctt gagcctgctt caatagctag acgttttgtc actgctgctg gtaggatttc
     6061 ctccttgtag gaagctggct gctcatcaaa gatattttgt gatggcattg ataccacacg
     6121 cacatggata ccatctgctg caagagcggc ttgagtatcc attgctagct tgacttcaga
     6181 gccggttgca atgataatcc catcaaggtc accctttgcc tctgacagga tataagctcc
     6241 cttattaagg ccatcttctg ccaattcctt agtaccttca agtacaggaa ggttttgacg
     6301 tgttaagaca agcattgtcg gacggtctgt ctcagcgatc gcacgcttcc aagcagcgtt
     6361 tgtttcattg ccgtcagctg gacgaataac gttcagattt ggcattgatc gaacactagc
     6421 tagctgctcg attggctcat gggtcggacc atcttcacca accgcgatag aatcatgcgt
     6481 catgacataa accgttggta gctgctgcaa ggctgccata cgaaccgctg gcaataggta
     6541 gtttgaaaag acaaagaagg ttccgccata aacacgtgtt ccaccatgaa gggcaatacc
     6601 gttcatcgct gctgccattg caaattcgcg tacgccaaac cagatgttac gaccagcata
     6661 atgacccggc tggaagtctg tctcagcctt aaccatggta ttgttagagg cagaaaggtc
     6721 agctgagcct ccccagaagg ctggcacctg ctcagagatt tgttggatag cctgctggct
     6781 agaaacacga ctggctactg ctgtgccaag ctcgtgagct tgcaactcaa cctctgccgc
     6841 ctcattagca aaggcttttt tgtattcggc tgctaactca gggtatgctg cttcataagc
     6901 tgcaaatagg tcattccatg cctgctcagc ctgctcacca cgcgcctgaa ggccttgtct
     6961 aaagcgctca gtcacctctt gcggcacctc aaaatcagca tgggtccatt gataagattt
     7021 cttagcaaag gcaatgcctt ctgcaccaag cggagcccca tgaacagctg aagttccttg
     7081 cttttcagca ccaaagccaa tgattgtctt tacttcaata atggttggct tttcagtctc
     7141 tgccttagct tcctcgatag ctttagcaat ggcctctagg tcgttgccgt ctttaacaag
     7201 gatatgctgc cagccgtaag cttcaaaacg ccccttgacg tcttctgtga aggccattga
     7261 ggttgggcca tcaagcgaaa tatcgtttga atcatatagc aagacaagct taccaagctt
     7321 caagtgacct gccagactgg ctgcctcctg actgacaccc tccataaggt ctccgtcacc
     7381 atttagagca taggtatagt ggtctacaat atcaaagcca ggtctattga acttagctgc
     7441 taagtgtgcc tctgccatag ccataccaac tgcattggca actccttgtc ctaaaggccc
     7501 tgtggttgcc tcaacgccat ctgtatgatt gacctctggg tgacctggtg ttttagagcc
     7561 ccattgacgg aagttcttaa gatcctcaat agacacatca tagcctgcta ggtgcaacag
     7621 gctgtaaagc atggcactac catgacctgc tgataggata aagcggtctc tatttgacca
     7681 acggcggctt gtctttggat tgactgtcat aacatgattc catagcacat aagccatcgg
     7741 cgccgccccc atcggcaaac ctggatgccc agaatttgct gcttgaatag cgtccattga
     7801 tagagtacga acagtattaa ctgccagctg atcaattgca tcaaatgtca taagtaaaac
     7861 ctctctgtgt attacaacta aaaattaaac gttttccatt gtctattgta acataaaagt
     7921 aaactgattt ttaacaaaat cctataaagt ccttaaattc ttatctagca ataagcattg
     7981 ctgttcctag ctttttgtga ttgacagctg tcttagatag agcacctatg ctcataagaa
     8041 aaagcaagcc tagctgttgc cagctaagca agcattcctc tttggtacct ccctttggct
     8101 acagtaagcg ccagctgcct gttaattcta gcgcaacagc aaagcaccag ctgatcctgc
     8161 cacctacaaa tagctaatcc caaactaacc gctacagcca cattagaata taaggagagc
     8221 tctatgctct tagcctattt tttaaaggaa gcccaatcct ccataaaggt ctttaagcca
     8281 tttgttgtca atgggtgctc agtcatcttc gcaaataatg gatctggaat ggttgcaatg
     8341 tgtgccccta gctgtgcaac agcttcaaca tgggcagctg tccgaatgct ggctgcgatg
     8401 atttctgctt ggaagccata caaatcaatg atcccacgca aatcactaat aagctgataa
     8461 ggatctgctc caatatcctc taagcgacca ataaatggac tgatataggt cgcaccagcc
     8521 ttcatggcca ttagtccctg actaactgta aaaataagcg tcacatttgt tttgatgcct
     8581 tcttgtgaca agacattagt tgcttttaag ccctctgtcg tcatcggaat tttcacgacc
     8641 acattgtcat gccacttggc aatgttccta gcctctgcaa tcatttcctc tgcggttagt
     8701 ccggtgacct ctgcactgat agggccgtcc acaatctcac agatttcctt gataactgtc
     8761 tcaaaatcac gaccctcacg cgagataatg ctagggtttg tggtaacacc gtccacaaca
     8821 ccaagctcat taatcgcacg aattgcctct acatttgctg tgtctaagaa aaatttcatc
     8881 ttaacctccg ttaattagtc tgttatcagt cattgaacag catgacgctg tttaccgtct
     8941 acattatcat tataaaagtc actcttagga tataaaagac caagtatcac acagtctagt
     9001 gttcaaaact agacctagct atgggactct gtttctttaa aaggcttgat tcttacagct
     9061 cctctgcaaa aaactgtgtg gctttgacag ctcttttcca gccttgatat aacttttctc
     9121 ggcgagactc actcatgctt gctttaaaca gctgacctgt agcatttaat tgctttagtg
     9181 tctccatgtc cttccagtag cctacagcaa gcccggctaa aaaggctgct cctagagctg
     9241 tggtttcaag attttcagca cgagcaatat caatccctaa aatatctgcc tgaaactgca
     9301 tgagcatgtt attcatagcc gctccgccat caacacgtaa ttgctggata gtgatccctg
     9361 agtccacctg catggtatca atcacatctc tgacctgata agcaatagac tgtagggtag
     9421 ccttaacaaa atcctctttt gttgttccac gcgttaagcc aaatactgag ccgcgtgcat
     9481 tggaatccca ataaggagcg ccaagacctg taaaggctgg tacaacatat acctcatcag
     9541 cattggttga agccaaggct agctgttcag actcaaaaga ggtttttatc attcgcaagc
     9601 catctcgtag ccattgcaca gcagagccag caataaagat agacccttct aaggcataat
     9661 aaaccttgcc attaatacca tatccaatcg ttgttagcag gttgctgctg gataattgag
     9721 cctcttgacc agtattcatg atgataaaag agcctgtgcc ataggtattt tttaccatac
     9781 caggctcaaa ggccagttgc ccaaataggg ctgcctgctg atcacctgcc atgccagcaa
     9841 tagctacctc tcctccgtaa aaatgaaaag aagccgtttt accataaatt tccgaattag
     9901 acctgacctc aggaagcatg gccttaggga tattcagcaa ggccaatatc tcatcgtccc
     9961 attttagctc tttgatattg tatagcatgg tacgtgctgc attagaataa tccgtcacat
    10021 gtaccgcccc gtccgttagc ttccaaacca gccaggtgtc aatcgtgcca aataataatt
    10081 ctcccctttc agctcgctct tgagcccccg gaacatgatc aagaagccat ctgagcttgg
    10141 tcgcagaaaa ataagcatct ataaccaagc ctgttttttc atggatcatt ttggtatagc
    10201 catcacgctt tagctgctct gcaatggagg ctgtttgtct agattgccac acaatagcat
    10261 tatagatggg cagacctgtc tgtttgtccc agactaccgt tgtttcacgc tggttggtaa
    10321 tgcctatagc ttctatttgc tctggcttta taccagactc gataaaggcg tctgcaataa
    10381 cagactgcac caaattccaa atgtgattgg cgttgtgctc aacccagcca gcctgtggaa
    10441 aaagctgtgg aaattccttt tgactactaa ccagcgcttc tcctttctta ttgaaaataa
    10501 tggcacgaga gctcgttgtg ccctgatcaa tagccataat ataggtttca gttcccatgt
    10561 gtcctccatt ctatcgctgc tgagataggc tctctcaatc atagcaagcg ctttctactc
    10621 tattatacaa catttacagc ccatagccta tccttctagt cataaaagta tcactctgcc
    10681 aaatcctaag ctgataatgc ctatcatttc aactaaacag cccttatcac agccaaatac
    10741 cagcaacaaa ggcgggctat aggctagcgc ctaaatggct gccaacaagc tccagctcta
    10801 tcaggcacaa caaggaacaa caaaaaacct aagccctttt agcatataaa ggcttaggaa
    10861 tgttacaggc ttttatcaca taagcggtga tagcttttta atcgtaaaca ggctcagagg
    10921 acttttctaa aatatctcca ctattagcat caatagtata gctgtactcc tgatccttgg
    10981 cgtcaaactc aatatcgtag accaccctac cgtcgtctgt ttctttcgtc agctttagcc
    11041 tttgggcgtc agctgctgtg attgaggcgt ccttaaaagc aagctccttg gccttgtcct
    11101 ctgaaatgcc agctgcttga tcagcctgac caccagctgc ttgagctgaa gcaggagcct
    11161 cagtgattgg ctcagaggat ttttctagga tctcaccggt attagcgtca atggtatagc
    11221 tatactcctg atccttagca tcaaactcaa tatcatagac cactctacca tcgtctgttt
    11281 ctttcgtcag cttgagcctt tgagcgtcag ctgctgtgat tgaggcgtcc ttaaaggcaa
    11341 gttccttggc cttgtcctct gaaacacttg ccttcctatg attctgagca ctgccatttt
    11401 gacctagagc ctgattctgt tgacgacaag ctgataggct gattaaggat agactcgtaa
    11461 gagctattac tgaaagtttt ttgattatca ttgtattgac cttccgtctt tattcatctt
    11521 atttcctcta gtatacatta aataatctga ttttacaatt ttaaagcgct aaaactctct
    11581 taaccaggct tactccctta tatgataacc cccaaagagc ccataaggta aaggtaagga
    11641 ctttgctatc cctcaaccaa gaatagatca cccagccgaa taaaaaaagc aattattggt
    11701 agaatgagaa gaattatttt ggtcttattt attgccttca ccagctatca atcactattt
    11761 aatgaccatt ttggtatgaa ccctcactgc cactcactat ctgacaccaa gctactttta
    11821 agtaccagca tcgatgtttc ttacacctcc agtgcgtatc catagccgac cttcagcatt
    11881 taccagcatt tctgattgat tacaaatact ccctaaactg ttgaaaaagt atctaaacga
    11941 accatacaaa acttaattta ccttttttct atataaatag ctaaaaaaca tagtaaggtc
    12001 acaagggata taagatttac attgcttata gtagtcgata agaaataaaa aattaaaaaa
    12061 ataaagtaag aagccccttc tttgcccctc ttagcactgt caaccagtat atagataaaa
    12121 attaaagcat aaagacctga aaaagtaatc aataacatct aatttacctt atatgccaag
    12181 catgctccta aagcagtaaa gccgtctata catactcctt ttagcaccgg atgaggtatt
    12241 ttgcaaaatg taattcctgt cttgagacct cctaatcccc cgataacagc attacctgct
    12301 gcatttcctc ctgaaatatc ttgcatttca cttattgcta atgctctata atgttccatt
    12361 tctattatcc tcctaaaaca aggttccaaa ctcagaatct ttctgttttt ctcatttcta
    12421 aaagcctcct gtgacaccaa tagatccaca agctactcca catactggaa atccaagtgc
    12481 tgcgcctgca cttcctgctc caatcacacc tgacacattg gcagcccaat tattttttcc
    12541 tccttcaaag ctagcaagca tttctgtagc cattacgtca aattattgta ttgattgcaa
    12601 atactcccta aaaatcgatg ttgtccagtt gcaaccttga catatttagt ataacgcttt
    12661 ttttgtaaaa cattcctcca tatcctaaac agtcgttgaa acgtcctaaa tgggagcatt
    12721 tttttcgttt aagactgcaa agtgaccatt aagggaaggc gtgaagcgac aagcctgtgg
    12781 ctttaggaac cttaaaaaca ttaaaagcaa gcttctcatt gctattaaca acacaaaaaa
    12841 agcaccagtc tggtcctcac taggtactag ttatcagtca cccccctaaa gttgacaaga
    12901 agccaaaaaa agagaactga ctagctctct tagtgtgcag acaaatctat ctgcttacat
    12961 taatgacaat tctcagaagt gcaaaagaca gctattagcc cttacttgag tacctctcct
    13021 ttgcttggcc tactagagat tctctcaatc aggcgactag tccggattaa aagccagtct
    13081 agccaagccc atgaaattgc tgatagagct cttggcgatt caccttatag tctttggcga
    13141 ttgtcttgat cgcctgatta ggcttcatgc cagcagcaat agcctgttga acaagtgcta
    13201 gcagatccaa atcctcagca ggctctgatg cgtcagcttg attggcacct gccacaatca
    13261 atagacactc acccttgagt ggatggtctg ctagataggt caagacctct gaaatctgac
    13321 cacgctggta ttcctcaaaa agcttggtta actctctcac cagcaccacc tggcgatccc
    13381 catagcaggc cagcaggttt gttagcgtat ccttaacacg ataaggagat tcataaaaga
    13441 tttgagtctc tggataatct gccttagtca tcaaaaatgc cctttgctgc ccagcttttc
    13501 ttggcaaaaa gccataaaac agatggggct ggggcgccaa gccactagca atgaggccgg
    13561 taatgcccgc agaagcaccc ggcaaagcaa caacagtaat atctcgatca atagctgctc
    13621 tgactagctc atgaccagga tctgaaatag agggcatacc agcatcggag acctgagcca
    13681 atgaccttcc agccaacaac aggtccagca aatctggaat tttatcataa gcattatgct
    13741 catgaaagct tacctgcttt gtctttatcc caaaatgctt gagcaacaga ccagtatttc
    13801 tcgtatcctc tgcacagata atatccacct cttttagaac attgaccgct ctaaaggtca
    13861 tatcctctag gttaccaata ggggtaggca ccagatagag aacccctgac tctttttctt
    13921 ccttgaagct cttttggatt tgcatgactc tactttctat ctaatagctc tcgacaaaac
    13981 atacactctt catcattttc acgacgttgc ccatagaaaa aattgcagat atgaaagccc
    14041 tcatcataaa tgccctccaa gtggtccttg ccctgcttag aagaggtctt ggccagattt
    14101 tcgtgctcca attgactcaa gcgctcacgt aatttggtgt tttcaagcct aaggatagta
    14161 ttttcctcta cgagtccttg gacctgcttt ttcattgctt caatttcagc taaagtcacc
    14221 atcaggtttt gtgaaaagcc atcaaaagcg tcaaacagtt cttttttatt cactaacttt
    14281 aacctcctct aaagcatagg ttaccaaggc cagctggtcc ttaaagcgaa cctgaatggt
    14341 atctgtaaaa agatcaattc ctgcaacctc acctggtccc tgcgctgttc ttactatagt
    14401 accataatca ggaaattttt tcttactttc ttgataaaaa tcgtcctcat attgtaggca
    14461 gcacagcaag cgaccgcagc agcccaaaga ctttgccgaa tgcaaggaca gcccttgatg
    14521 ttttagcatt ttgattgaga ctggaggaaa ctctcctaaa aagcttgaac agcatagtgg
    14581 gcgaccacag ggacccagcc ctccataaac ccttgcctcc tcacgactat taatctgacg
    14641 cagctcaatc cttgtcttga aataggcagc caaatccttg aggagctggc gaaaatcaac
    14701 acgctcctga gcggtaaagg taatcaaaac ataacgtctc tcaagggaga aaacaatgtc
    14761 aaccaaggtc atgtctaagc catttctgtc aatcatctct gctacttttt gctttgactg
    14821 ggctgctagc tgaaggtttt gctggtaagc cttgtagtcc atgtcattgg caggtctcaa
    14881 aacagagggc atatcctttg gcaggtcgtc cttacaaaag ctttttatcg gagaattgac
    14941 cactgccaat cgactgccct tgccatcaga tatgacaagc ttggtttgca caggaaaggc
    15001 ctgatcggtt tgaacgtacc tgacagagca ggtgtcacaa tatttaattc caatcgtact
    15061 tatcatgaaa tcaccatata ttctaacgta ttttgaaagc tgacattgct ttgccacata
    15121 agtctagcct gataaacagc ctccagatag gtaaaagcat tttgtcgact gtagtccttc
    15181 gccaagatta aggttaaaag agttagtgcc atgtcctgct cctctttttc ctctgctagc
    15241 tgaaccaagc gattaagctc cagataagcc tgttccttat cctgaaacca gatggaaaca
    15301 aaacgctcag cctgcgccat cagctccaac agcctggtgt tttcagaaaa agcggtaagc
    15361 tgctgggcat tggctgctaa tctggctaag aggtctgctt gatgtttcaa aagccccttt
    15421 ttttgggcca gctcagagag gtagtgctca tcttttggaa agtgaaaaac ctgtgtacgg
    15481 ctcttgatcg ttggtaggac ctgattgtca tcattcgtta gtaaaaacat atagcaatcc
    15541 ccttgtggct cttctatata ttttaaaatg ctgttagctg cattgacatg catcttatca
    15601 caatccttaa tgataaaaac ctgccgcctg ccctcatagc cggtctgcga aaaatttgtc
    15661 atcatttctt tgacggtatc agtcttgata agctgaccga caggctctaa gatggtgaca
    15721 tctgaaaagt cattgtgctc aatcagctgg caagcacgac agtgatgaca aggagcattg
    15781 cctctttttt gttcgcaaaa aagagtcttg gctaaaaaaa gagccatgtc aaaattggca
    15841 aaatcacctg aaaagaggta ggcatgattt agacgttttt tttgcaaaat ctcttgaaag
    15901 gcctgataga ccctaggagc cttttgagcc aaatccattc ctaacctcct gctatgcttg
    15961 actgtgtgtg ataatggcag ctaaagccgc tgacacaacg ctttctaagt cctgtgatgc
    16021 atcaatcttg acaatacgct ggggattttc caaagccagc tccagatagc ccttacgaac
    16081 acgctggtgc aaatctaatt gctcaagatc aagacgattg atctctcgct cagtattttg
    16141 tgcaatcctt gccaatccaa gctctgaggg cacatcaaaa tacagggtta aatcagggtc
    16201 aacaccatct gttgcaaaat gattgagcca ttgaatggct tgcttatcca gccctcttcc
    16261 ggcgccttga taagcaactg aactgtcaat aaaacgatcc accaaaacca agtgtcctga
    16321 ctcaagagct ggcatgatct tttcaaccaa atgctgcctt cttgctgcaa tatagagcag
    16381 cagctctgtt ttatcgtcca tggtcgtgtg actgacatct aagatcagct gacgaatctt
    16441 ctcagcaatc gcaacgcctc caggctctct cgttgttaca atggtttgtc ctagagctgc
    16501 ctgtaagagt ggcaccagtc tttccagcac cgttgttttt cctgctccgt ctggaccttc
    16561 aaacgttatt aattttcctc tagtcatctt tattcctttg tttatcgtta cctctatttt
    16621 accaaaattt gcctgaaaaa gcactgccaa ttcattgggc agtgccagat cagaaaaaag
    16681 cctttttgtg ctgcctttta ggcgatagga ataaaaagcc agccctcaaa gcagcagcct
    16741 aagacttgtg cctcacacct caaagcctat gagcagccac tcgataaatg acaatcgtct
    16801 cagctcttat tttctttgcc taagcaagcc agcagggctg atccatcagc tttgagcaat
    16861 tgatgagcta agacatgcta tataagacag gatcaggcct acttagccct gctcaggtag
    16921 ggcttgaggc tctagaggct cacgatgtaa attcccaaca aaatcacaat caatgtcatc
    16981 aaaggctgat accttcacct ctttgacaaa tgttagccga ctaatgtcct ttagcttttc
    17041 ttccatgtcc tctttattga tgtaaataac aaggtatcga gaacgcctgg aatggtagta
    17101 caagtcacca tatttcatca cttttctagc gtctcgattg taatacaggt agataaccag
    17161 cccaattctc tgctgttttt gaaacattta ggtactcttt tcttttatat tttgatacgg
    17221 tccaagctca tgtcgaggtc tatttgtcgc caagggaagt cctgtgtcga caagaatatc
    17281 ctcagacact gcttctgcaa tagctgtcga aatcgtcgcc aaaacctcct gcaaatcaac
    17341 ctgtgccaag cgcagatcag caaccaatgg atgcaggtca agctggcgct tttgatgaag
    17401 taattggcag cgcaacgctc tagcatctgg acacaactta agcaagtcct gcctaagctc
    17461 ataatcctgc ttaagctcct caaataaggc taactcggtc tgtagggcca aatctgcctc
    17521 aaaagccttt ttagccaagg cataggcctg atactggctg cttgtcctaa tatcctgaac
    17581 cagctgctca atagcctttt caatggcaaa caattcttca tttatgatta gcataggtta
    17641 attataccat aattttaagg aagatagccc tctttagcat gcaaaaagcc cctgaaacaa
    17701 tttgtttcag aagctgttaa gctattttac taagctctct aagctagctc attattttcc
    17761 atgatttcat caataaagcc ataggctagg gtttcttctg cgctcatcca ataatcacgc
    17821 tcagcgtcct tatggatttg tttgatcgtt ttaccggcat tttgtgccaa aatcttttcc
    17881 aggcggtgac gtgtctttaa taaatgctca gcagcaatgg ccatatccgt ctgctgcgta
    17941 ccacctcctg tgcctcccat aggctggtga atcatatatt ctgcatttgg aagcataaag
    18001 cgcttgccct ttgcacctga tgaagcaata acggttccca tagaagcagc catacccata
    18061 acaatggttt gcacatctgc cttaataaag ttcatcgtat caacaatagc taaaccagct
    18121 gatacagagc ctcctggggt attcacatag aggtaaatat cttttgtgtt gtcttgggca
    18181 tctaaaaaca agagctgcgc aataacagag tttgccatat tatcctctac tggaccagtc
    18241 agcatgataa tacggtcctt taacagacgt gaataaatgt cataagaacg ctctccacga
    18301 ctggtttgtt caataactac aggaatcata aaaatctcca atctatcgtg actgtctaac
    18361 accactctgc ctcatgcagt gacaggcagt caaacacatc tttttataat gattgacctt
    18421 attataatct cttggtcaaa aaaggtcaaa tgataaactt gcttttaaaa accttccagc
    18481 ctaaactaga aagtcttatt agctttagca ggctagcctc tagcaagcag agcctagcac
    18541 aaccaaagcc tgtagccttt tacttggtac caaataagcg atcaccagca tctccaagac
    18601 caggaacaat gtagccatga tcatttaatc tttcatcaag ggctgcggta taaatgtcaa
    18661 catctgggtg agcctcctga agctttttaa ccccttctgg tgctgctacc agacacacaa
    18721 acttaatatt agcagcccca cgctttttca gtgaatccac tgcaagaata gcagagccgc
    18781 cagtagccag catcggatca acaataaaaa tttggcgctg atcaatatcc tctggcagct
    18841 tcaccaaata ttcaaccggc tccaaggtct cctcgttacg atacataccg atgtgaccaa
    18901 ccttggcagc tggcacaaga ctaagaaagc catccaccat accaatacca gctctaagaa
    18961 tcggaacaat tgctaatttt ttacctgcta actgcttttg aaccgtcttg gcaaccggtg
    19021 tttgaatctc aacatcctct aatggcaagt cacgagaaac ctcgtagccc ataagcattg
    19081 caatttcatt gaccagctct ctaaaatcct tggttgaggt atcctgacga cgcaggattg
    19141 atagcttatg ctgaataagt ggatgcgaaa taacctgaca ttttcccatg atgacgtact
    19201 tccttcttta ttttttacac ttttgctatt ataccaaaaa attgaaaacc ttgcttactt
    19261 ttttcagatc cggttgaaat gataaaagca agaatctgat cagctagctg cctgcttcag
    19321 ctgccttgat cttgggtgtc aaagtcccaa tttttggcga tacctagctg ctctgctgcc
    19381 aattaatttg tccagctgac gcgtcaataa cgtcatgtag gcgtaaacac ccattcccaa
    19441 gccaccaata atcactaagt aaagcaggct agtcaatctg cctgtcggct taaacaaata
    19501 gcccaaaaac cagttagcta gtagcacaat caggcccatc aatgctgtct caatcaccgt
    19561 tagtaatata cgcttatgca gcagcttacg gttaaatcgt gtgacctgat gtagacgacg
    19621 gtacatgaga tagataggca ctagcaagcc aagggtcgta gctaacaaag gaccataagc
    19681 atgaaacaga tagatcaaag gaacctgcaa aaccagcttg acaaaaacac cataagcaaa
    19741 ataatagatg gccttacggt tttcaaacag ggcctgcagc atcggagaaa aaagcgtata
    19801 caaggccatc aatagggtaa ggcaaagcac agcaacaaac agcctaacag cctgtccctc
    19861 gctactaccg taaaaaaccg tataaagagg ccttgccagt ataatagctc ctgtcagagc
    19921 aggcaataaa aacatcagca gcatttcaat gttgttaatg atcaggcgcc ctgctgctcg
    19981 catgtccttt ttaatgtaat tttctgtcaa taaggcaata ccaacactac caattgaagc
    20041 ggctactgca atgagcacca tggtgatttt agcagggttg gcgttaaaat acccaaacag
    20101 cacccagagc tgagaacgcg tgtagctggt aaacagagtc atcgtattga caaaggtcca
    20161 ctgatcaagg agctgaaagg cctgaatcgc acttcctgta ataataaagg gaatcgactc
    20221 ctttaacgtt tcaataagca agcccttgat gtcaatagga atcgcatgct ctgtcttggt
    20281 aaaaatagcc tttaaaaggc cctgcgtcca gaaataataa aagagcaccg ccatactggc
    20341 tatcattcca ataaaagcag caaaggtgga ctgcgtaaca gctgcaatat agtccttaga
    20401 ccccattttc atgatgaaaa aggttgttag aagcatccag atcacacgaa ccagctgctc
    20461 agcaatttgg ctaagagcat agggcttaat ctccttatag ccctgaaaaa tccccctaat
    20521 cacgctcatc actggaaaaa caaaaacagc taatgataag ctatgcataa tcgggacaag
    20581 ggtctcatca ccaccggaca agcgagcaaa gagcggagat cccagataca tcagcactga
    20641 gaaaatcaag cctaatacca gcataacctt tagagtgctt cgaatgagct gatagctatg
    20701 ctcttgctgt cccatcgagt tgtacttagc gacctgctta gcaatggcaa catttagccc
    20761 tgttgtcgaa atcaacaaaa aataggcata cacattgtat cccatattaa agagcgcatt
    20821 tgcctgtatc gcatactgcc ccatccatat gtaccatgga ataatatata gaacgcctaa
    20881 aagtcggcta ataaaattac ctgcggtgga ccaggctgct ccctgaacca tcagctgttc
    20941 ttgtgtcaat tgtttttttt ctgtcgacat atccgttctt cctagttttt atagctttat
    21001 tataaacttt tgcttgtgac ttgtaaaaca agaacattaa ggataaaata aggctatgat
    21061 aacaattgag cacttattaa ccattttaaa aaaggaccat aatttccgag aggttcttga
    21121 tcaagacggc taccacttta actatagcgg tctacagttt gacagcctta gctacgacag
    21181 cagacaagca gatgagcaga cgctcttttt tgctaaggga tcagctttta aggctgactt
    21241 tttgagacag gccattgcca agggactaag actctatgtt tcagagattg actatcaggt
    21301 agggatccct gttattcttg ttaacaatat taagcacgct atgagcctag ctgcgatggc
    21361 cttttatgat tacccacaaa ataagctcaa gctattagcc ttcaccggaa caaagggcaa
    21421 gacaactgct gcctactttg cctatcatat gctaaaggaa tctcataagc ctgccctgct
    21481 ctctacaatg aacacgacct tagatggcca acactttttt aaatcgcagt taaccacacc
    21541 tgaaagtctt gatttatttg cgatgatggc tcagtgtgtg gctaatggca tgacgcattt
    21601 ggtgatggag gtctctagtc aagcctactt ggtcgggcgt atctacggct taacctttga
    21661 tgtcggtgtc tttcttaata ttagccccga tcacatcgga ccaatcgagc acccaagctt
    21721 tgaggattat ttttaccata agcggctctt aatggaaaat agccgagctg ttgtggtcaa
    21781 tagcggtatg gagcatttta atatcctagc agagcaggtg gctgataagc ctcatgattt
    21841 ttatggcaaa ggggcttgca ataggctgct gcagcggcag gccttctcat ttcaagcagc
    21901 cggcaaggta gctggagact atgcgattca attaattggc agcttcaatc aagaaaatgc
    21961 tatggctgct ggactagcct gtcttcgact gggggcaagc ctagaggata tccgccaagg
    22021 cattgctaag acaaacgtcc ctggccgcat ggaggtctta accatgacca atcaggccaa
    22081 ggtatttgtt gattatgcac ataacggtga tagccttgaa aagctcctat ctgttgtcga
    22141 agagtaccag aaaggccaga tttacttgat tctaggagca ccgggcaata aaggcgagag
    22201 ccgtcgggct gattttgggc aagtcatcaa ccagcacccc aatgttcgta ttattctgac
    22261 tgctgatgat cctaattttg aggacccaca gctgatttca gaggagattg ctagctatat
    22321 tcaccgcgag gttgatatta tcattgaccg taaagaagca atcaagactg gtatggagcg
    22381 ctgtcagaat gagcaggatg cactcattat tgctggcaag ggggctgatg cttatcagat
    22441 tgtcaaggga caaaagactg cctatgcagg tgatttagcg attgcaaaga gctacctata
    22501 gactggtcta acaggctaaa cagtaataat tcttaagatt actgataatg attctaagct
    22561 ggctcctttt ttagcataaa ctcagtaatt agattctgaa aggctttttt aggccttttt
    22621 tctatgctat aatgggatag cttttaagag aaagcgcact attatagtca gaccaaaaaa
    22681 gcgactagca tttcataggc tatcagcccc ttagaatttt gctagctggc tttgcttgac
    22741 tattagaaag gagaaaaacc atgtcaacaa tcagtgctga gaggatttca gctggctatg
    22801 atcaatcgct tatcatcagc aacttatctg tcactattcc cgaaggaaag gtaacaacca
    22861 tcatcggtgc taatggctgt gggaagtcaa cccttttaaa gactctggca cgactattgc
    22921 cactcaaagc agggcaggtt ctcttagatg gacaagccat tgctagacta gcaaccaagg
    22981 acgttgccag aacactagca gttttacctc agctgcaaga agctactaca gctactgtct
    23041 atgagctggt ttcttatggg cgttatcccc accaatccta cctaggacaa ctcagtcaag
    23101 ctgataagga taagatttgc tgggcaatgg aggtcacaag catggcaccc tatgctcatc
    23161 aggctgttga tgccctgtca ggcggccaac gtcaaagggc ctggattgct atggccttag
    23221 cacaggatac tgatattatt tttctagatg agccaacaac ctacttagat atgaatcatc
    23281 agctcgatat tttagaatta ctaaaggagc tcaatcaggt ctctggaaaa acaatcgtga
    23341 tggtccttca tgatttaaat ctttcagcac gctactcgga tcatctgatc gccatgaaaa
    23401 atggacatat caaatattct ggagaggtca accaggtgat gacgccagag atgattcaag
    23461 acatttttca agtaaaggct cagctcgtca ctgatcctct ctatcattgc cctacattgc
    23521 tgacctatca gctgatataa atttattcta ggagaataga atacatgaaa aaactactgc
    23581 ttattttaac tgtttttgtg acagctttta cattagtcgc ctgctcaagt caaagcaagc
    23641 aacaagaaag caccagcaaa gcaagcctat cccacaagcc aaaaattgct ggagtgacct
    23701 attatggtga cattcctgtc aagccaaagc gcgtggttag cttagcagct acatatactg
    23761 gttacttggc aaaattagac cttcatctgg tcggtgtcac ctcctacgac aaaaagaacc
    23821 ctgttttaac aaaaagcatt actcaagcca agcaggtggc agctactgac ctagaggcta
    23881 ttacagcact agagcctgat ctcattgttg ttggctcaac agaagaaaac attgaccagc
    23941 tagcaaaaat cgcaccacta atctccattg aataccgcaa gcgtgattat ttgcaggtgt
    24001 tttctgattt tggccgtatt tttaacaagg aaaaggaaac tgaccaatgg ttggccgact
    24061 ggaaacaaaa aacaagtgac tatgaaaaag aaataaaaca agtcaccgga tcagctgcta
    24121 cctttacaat catggggctc tatgaaaagg aaatttacct ttttggtaag gactggggaa
    24181 gaggtggtga aattattcat caggccttac attatgatgc tcccgaaaag gtgaaaaaag
    24241 aggtgtttaa gcagggctat ctgtccttat cacaggaggt tctaccagat tatattggtg
    24301 attatgtgat tgttgctgct gaggatgacc aaaccggctc agccttatat gagagcgacc
    24361 tttggcagca gatccctgct gtgaccaaca atcatgtcat caaggtcaac gctaatgtct
    24421 tttacttcac agacccactg tcactggagc accagcttga ggttctaaaa aaggctatcc
    24481 tctcaactgg tgcaagtcaa taaaaactta agatgacagc tcaacatcat actaagccta
    24541 aactagctaa agcagctcct ccttggctga tcttaacctt tatcagctta actctagtgc
    24601 ttgccattta ctgcagtctg aggtttgggg ctgtgtcact atcacatcag gagctctatc
    24661 atattctact tggaaagcag gaccagggtc aaaaggccag cattattttg gacattcgcc
    24721 tgccccgctt gattttagca gctctagttg gtgctgcact tgctgtttca ggagctatca
    24781 tgcaaggcat taccagaaat cccattgccg agcctggctt actgggaatc aactctggag
    24841 ctgggctggc attagtcatc ggctatgctt tttcccctca tcttcattat tcgacaatta
    24901 tattactttc cttgctaggg tcactcttag cgaccctatt aattctcagc ctagcctatc
    24961 aagctggtaa gggctacact caaatgaggc ttattttagc aggagcgatg atatctatgc
    25021 tactgtcagc tatcggacaa ggaataacaa cttattgtca cctagccaat gccattattg
    25081 gctggcaggc gggaggattg atcggggtca attggcagat ggttagctat gttgcgccac
    25141 tcatcatctg tggcttagcc ctatcttatc tgctagccta tcatttgacc attttaagct
    25201 taagtcaaga gcaggccaag gccctagggc aacgcacctt cttgattagc cttatcttta
    25261 ttggacttgt gctgcttctg tcttctgctg ctgtagcagt agccggcagc atttcctttg
    25321 tcggcttgat tatccctcat gccatcacat tagtcactgc taaggattac cgctggatcc
    25381 tgccgctagc tactcttctt ggagccagct ttatgctttg ggtagacttt gcctgtcgga
    25441 atatcaatcc cccctatgaa acaccgctat ctgctttgat cagctttatt gggctgccct
    25501 gctttttatg gctagttaga aaaggaggtc gcttttgaca gctactaaaa gacacgtccc
    25561 attatttcta ggactaatct ctggactggt ctgtttgatg attatttcct tgtctattgg
    25621 ggaatctagc atgtcaccat tggaggtcgt cagggtgctt tttggtaaat ccactgctga
    25681 tatggccttg atcatcacca acattagact cccaagaatt ttagctgcct gtatcggtgg
    25741 cggctcactg gccctttctg gcttaatgct gcaaagctta acgcgaaatc atctggcaga
    25801 ttctggcata ctaggcatta atgctggtgc tggtatggct attacccttg tcatatccta
    25861 cagcactagt aacagtctga ccagcaggca agggctgccg cttatgacca tatccggggc
    25921 aatggcaacc attgtcttgg tctacctgct ctcacttcgt catggccata ttgatcctat
    25981 tcggctgatt gtcactggcg tagggctatc aaccatgcta tctagcctga tgattgcctt
    26041 tgtcggcaat gtgaaccgtt ataaggtgga ttatgtgatt cattggctaa gcgggcagct
    26101 aacaggcgat gattggtcca agctaagcat tgttgctccc ttattgggga tcacttggct
    26161 gctagccttt agtcaagcct ataagctcaa catcatggca ttaaatgatg aagcaagcat
    26221 ggctctaggc ttcaagctcc atcagtaccg taccattgtt cttgcactat ctgcgattct
    26281 ctcagcccta agtgttattt tggtcggaaa catcaccttt attggtctga tagcaggcca
    26341 taccagcaaa cgactagtgg gagctgatca ccgattaagc ctgcctgtca gccttttcat
    26401 cggcatgatt ctgcttctct tggctgacac tatcggacga gtctatctcg tcggcagcaa
    26461 tataccaacc ggtattcttg tctcaattat tggtgcatcc tattttctct atctgatggt
    26521 caaaatgaca taagagcctc tgctgcatag cttaaagggc tcagcaagca taaatggctt
    26581 agactcaact gttttacagt gtgggtctaa gccatttttt attcatcaag tcaactctta
    26641 atcagcgtag aaaatcagct gctccttatc aaaagccagc ttcaggcagt atttagtggc
    26701 ctctactttt tcaatatagc ctagaagctc caaggcattc acaaaaatat ctgtccgctt
    26761 ttgcataaca atctcttttc tagcaaattt tagaagaaag ctggtcatgt acttcaaggc
    26821 atagtcctga ttcacatcac ctaatagggc atagagcctt aattgctcat cagatagggc
    26881 ttcccctctt cttaagcggt aaaaataatt ggcaagcgtc agcttatctc ggtcaatggt
    26941 tgttttttcc ttgatcaaaa cctgattggt ctgattagac agcactgtct caaacaccaa
    27001 ggccatcaaa gcttcatata gatctgatgc cctatccaca aagattagat cttctaatgt
    27061 cacctgctgc aggtcatcta gcaagggcag acacagatag tagcgtctgt tttttcgaca
    27121 gatatagcca gcctgaatgt aagcttcaag cgccttatca atccccttaa catgagaaaa
    27181 ggcctgctta atgtgacgca gggttacgtc atcatgctga ttgaggtaat gaataaggtc
    27241 ttgaaaaaaa ggctgacgcg ttaatttatc agggttaaaa atggtaatca tactactatt
    27301 atagcaaaaa gaccaaaggg ctgctgataa aaatcaacac ccctctacag gcaagctcta
    27361 tgctccaaag ctttcagtta attgagggac aacctgcttt ttacgagata cagcacctgc
    27421 taggaaagca tgattatcct caagcttaaa gctaaaggct gcctcaacct tatccatatt
    27481 cgcaccaagc gccaaaatct ctgaatttga attaacaata tctgtaatca tcaagacaaa
    27541 atcagaatag ccctcacttg ccatcacctc tctaatagcg gcctcaatag cctccttgcg
    27601 ctctaacacc tctgcaatgt caacggtatt gacctgggct acacgaactg cgttgccatt
    27661 taattcaaag gtcttagcat caatatcaat caattctgct tctgatttac ttgcaaggtt
    27721 tgttccggcc tttagcatag ccataccgta ttcctctagc ttaactcctg ctaactctgc
    27781 taattccgca gcaacacgat gatctgaagc atgcgttgtt ggtgatttta acagcaaggt
    27841 atcagaaatc aagccagaca aaagcatgcc tgcaatgtcc tttggcacat caaccctatt
    27901 ttccttgaac aggcggtaaa caatagatga ggcagagcca acaggttcga cacgcatata
    27961 aagcggattt gctgtctcaa aattagccac ccgatggtgg tcaacaatac catacacctc
    28021 aacctcacga atatccgaaa tagactgtgg aaattcgtta tggtctgtta gaataacatg
    28081 actagcaccc tctgcttttg ctgatgtcac cactcttggt gctgataccc caaaatagtc
    28141 aagggcaaag gctgtttctt catttgggtc acccagagcg actacctccg tatccaaatc
    28201 aaaggctttt tttgctaagt agtcaaaagc atacgatgat gcgatggcat cagtatctgg
    28261 attttgatga ccaaaaacta atagttttga cataaagttt ctacctcatt ctctttattc
    28321 atcttattgt agcagaaata ggctctaaaa tcaaagaaga ttccccagtc acaggccaag
    28381 agtctaaagg gcataagggc acagaatctc aggtattaaa gagtcctgtc aaacacacaa
    28441 gaacaggcaa gccagtccaa aaagcaatgc cttctataat gagctattca gctatttggg
    28501 gacaatacac tgtccttgat tggtttaatg cttcaaggat tactttttgg cacgtgtctg
    28561 agctcgctta aaaacactga aggtctcatc aagccagccg cttcatcagc aaaaaaacgg
    28621 ctctataatt tccatggtgg atttacccac tacagaaatt atagagccca tttacctcgc
    28681 tttgcacatc acacaagaga aaacgagctt cgtctcgtgc ttagttatca gtcacccact
    28741 acagttgaca tggggccaaa aaaagctggg catttcccaa ctctagctta gcctatgatt
    28801 gatgaatacg gttcatgtat tcagtatagg attctgtatg cagcagcttt ttggcattct
    28861 ccacccgctc cttggttggt ggcttaacgc cctcaagctg gtatggaatc cctaactcgc
    28921 gccatttgaa ctctcccatc gtatgataag ggagtacctc aaacttgtcg acatttctca
    28981 aggtcttgac aaacgcatct aagcgtacca agtgatcatc aatgtctgtc aagccaggca
    29041 ccaagacatg gcgaatccag acgggcacct gcctatcaga gaggtagcga gcaaactgca
    29101 ggatattttt attgggctga cgggtgacaa gcttatgctg ctcctcgtca atctccttta
    29161 agtccagcaa aatcaaatca gtaactgcta ataatgtttc taacagctca tggtattcag
    29221 gggttggacg ataggcaaag ccacaggtat ctagcgttgt atggatacct agctttttgg
    29281 cctcagtaaa gagcgcagtg ataaagtcca tttgcagcat agcctcacca cctgacacag
    29341 tgattccacc ctttttcccc caaaagtgcc tatattgcag agcctccttt aggacatcat
    29401 taacggttcg gcgttgagat tgattggttt ccatagccca ggtgtccgga ttatggcaat
    29461 actggcaacg catcttgcag ccctgcaaaa aaatgataaa acgtatcccc ggaccatcaa
    29521 cagaaccaaa gctttctgta gaatgcacca ttccagttac ttgcccataa tctacttcaa
    29581 ccattgtgtc tccttcaccc ttgtaaatgg ttttacgttt tcattatatc atgtttcatc
    29641 aaaaagacta agctcaatgc ctagtcttca gtaatattct gttctatatt agaaatagta
    29701 agtttcaatt tggtgatacg accgtccttt actttgtcat tgaccaaaac cagatgcttt
    29761 tgcttgctat cacaggcaaa gctctctttc tccttttgac ttggaatggt accaatccct
    29821 gtcaaataaa agcccgcgat ggtatcgaca tcatcacttt ctaattctgt gtcaaaatac
    29881 tcgttaaagt cgttgagcgt cattgtccct gtgacaatat aggtgttgtc atcaatgtga
    29941 tgaacaaatt gctcagcctt gtctgtctca tcatcaatct caccaacgat ttcctcaagc
    30001 aaatcctcaa gcgtcaccaa acctgcaacc cctccgtact catcaagtag gatagccatc
    30061 tggttttgag tatttcgcaa ttgcctcaac aaatcatcta caaaaatcgt ttctggtaca
    30121 aagagcggct cctgcagaag ctttctcatg ctgatgtttt caaagccctg acgaaagcct
    30181 gattctaaaa gccttttggt atgaattaag ccgatcacct tgtccttgtc aacatcataa
    30241 actggaatac gagagaagct ctgctttagg atttccttga tattgtctag cgtatcatcg
    30301 ttaatgtcaa tcatgaaggc atctgtcctt ggaaccatca cctcacgcgc catcatctca
    30361 tcaagcgaga aaatcccctg cagcatttca atctcttcgg catcaagcgt tgcctcgctg
    30421 ttagtcagca tgtactcaat ctcatcacgc gtcatgcgct catctgcgtc atcaaaggtc
    30481 attggggtaa tccggctcag taaatttgtc gacgccgata agagccaaac aaagggacta
    30541 accaatttcc ccaagataat gatcactggg gcagaaatca cagcaagctt gtcttttaga
    30601 ttcatagcta tccgcttggg gtataactct cccaaaacaa tcgagacata ggtcaagaac
    30661 accaaagaaa taatgctacc agctgtttga gcggtcgcag aaccacctaa ccagccagaa
    30721 ataacctgcc ctaaagaggc tgacaggctc gcccctgaca agaggctaat aaaggtaata
    30781 ccaacctgaa tggtcgataa aaagttattg ggctgctcta aaacacgcag caagcgatca
    30841 tacctcttat ccccatcggc agccttttgc tccacacgag agcgatttaa ggataccaga
    30901 gccatctcac tggctgagaa aaaggcattt aacaaggtta gaatgactaa caataaaaac
    30961 tgaatcaata aaggctgact cacagggtct tccattaata taactcctaa aacataatat
    31021 actacttcat tatatcacaa ttgtcgccaa agattgctga tttatttctt tttcctgaga
    31081 aatcacagac agtctaagcc ctgacataag gctggctgaa gcttaatcag tagctgctat
    31141 tttttccagc atgattaaaa atggcggctg attcatctga ttgatcggct gatagagcat
    31201 tgctgttacc tggcgctgat tgagctgacc aatatagtcc aaaagctctt ccttctccct
    31261 actaccgcca tcatgaccat aatacaccat gatagcaatc cgtccaccta gctcaagccg
    31321 atcaagtatt ttagctaggg ctaatatggt cgtctcaggc cttgtgatca acgacttatc
    31381 tgcattgggt agatagccca gattaaaaat ggctgcccga atgggctcct taacatattg
    31441 atccacctgc tcgtgtccag ctaaaataag ctctgcatta gtcaagcctt gctgctccaa
    31501 gcgctcttgt gtcttggtca gtgcctgctg ctgcacatca aaagcataaa ccctttgtga
    31561 cagacttgct aaaaaggcag tgtcatagcc atttcccata gtagcatcaa cagcaatact
    31621 ctgcttatcc aaaacttctt ttaaaaattc atgtgataca tgaataggac gctttatcat
    31681 cttatcctcc taagcaaata cttcaaatgc cgcgatacca tctagtatgt ctaagtcaat
    31741 atgccttcgg ccgtaacaat ctagcacata atctttatac cgatctgttt ttagattgaa
    31801 ttgaagcgac cagatcagcc aaaaaagatc aatatgtcga tcgctttttc ctgcctcccc
    31861 ccaatcaatc atggactgaa attgccaccg atccaagatc atatttggca aacaaaaatc
    31921 cccatgaatc agagtttcat gctgtaacaa gagcttaagc tcctgaatcc gcctgtaagc
    31981 ctcctcctgg gactgaaacc gttgctgagg cggtaaaaag cactgattga accgcccttg
    32041 gtgataacca gcctcagcag cttcgatata ggctagcgtt ttgtcagcta caggaaaatc
    32101 agacaaagac aggctatgca gctttagcat atgatcaact aagatacgac ataagcgctt
    32161 gggatcggac aaatattcaa tatgactggc gtcctctcct gctacctttg cggttaaaag
    32221 ccaatcctga tcaccgctga tataatcaag cacctctgtt gctaagccct tactatgaca
    32281 ataccgagtt agggcggcct ccttggcaag cctaccttta gcggctgttt ttagaaaata
    32341 gccctgccct ttatcaatag cataaacacg tgcctctgcc gagctactgc tatcataaac
    32401 caaactgttt tgtaacagtt tttttaaaac aggtggtagg ctcagctcct ctcctgctat
    32461 caatctttgt ttcattgctt cccccgatta tcccttaagc ttacagccct gccagctatt
    32521 tcttctttcc atttctaggt caatcgcatt caaaacctcc catttattca ggctccacat
    32581 gggaccaatc agcatgtccc taggcgcatc acctgtgatg cgatgaataa tgatatgctc
    32641 aggtatgatt tctagctgat cacagataat cgatacatag tccttctgac tcaagagctg
    32701 caagcgtccc tcatgatagt ctctttgcat acgcgtattg gtcatcaggt gcagcaaatg
    32761 cagcttaatg ccttgaatat cattgtctgt gacacagcgt ctaacgtttt cgatcatcat
    32821 ctcatgggtt tcaccaggca agccattaat caagtgagac acaatgttaa tgttagggta
    32881 ctgcctcaga cgctgaaccg tttccttata caagtcataa gaatgcgccc gattaatcag
    32941 ctgggaggtg gcttcataag ttgtttgcag cccaagctcc actgtcacat gcatgcgctc
    33001 tgatagctca gccaaataag caatcgtctc atctggcaaa caatcaggcc ttgttccgat
    33061 attgatacca acaacgccag gctcattgat tgcttgctca tagcgctcgc gaataacctc
    33121 tagcttatca tgcgtattgg taaaattttg aaaataaacc aaatactgat tgacctcagg
    33181 ccacttgcga tgcataaaat caatttcttt gtaaaattgt tccctgatag gtgcatcagg
    33241 cgccacaatc gcatcacctg agccagaaac ggtacaaaag gtgcagccac catgagcaac
    33301 tgtcccatca cgattaggac agtcaaagcc agcatcaatg ggcaccttga aaattttagc
    33361 accaaataaa cgacgataat actcatttaa ggtctgatat ctttttgtca tgcctctatt
    33421 gtagcacaaa tcccccgatt aacagcagaa gatctcaatt ggctgctact tctctgattg
    33481 atgagccaaa gcaaggcaac taaaaaggat tgaagaagac ctctggaaga gacctgcctt
    33541 caatcactag cttttctaga actgatctgt aacgcgccat acagctgact gatcactgga
    33601 tttacttttg ctttagctga aaacgccatt caaagcgctt ttgatcataa aaaggataaa
    33661 gcagctgaag tatgccaaag cctaaggcat agccagccaa cacatcgcta ggataatgca
    33721 ctcccagata aatgcgtgac aagcctatca gcaaaatcaa ggccaaaagg gctatatcaa
    33781 ccagccagcg taaggaggct gactgcaatc tttgatggca aataatcagc agacttccaa
    33841 taatcaaaag gcttcccatc gaatggccac tcggaaaaga atagccagaa gcatgcacca
    33901 aatgctcaat gctgggtctt ggtctttgat acaagagctt tagcacccaa atcaaaaggg
    33961 ccgcaaaaac accatttgat aggacaaata aggcctcagc tctccagctc aaggccaata
    34021 aagccagcac agcaacaaca acaatcactg cctgtgtact aacatttcca gctacagtga
    34081 tccctttaaa aaactgggtt agcccttcag gcagatgacc tcttagggct aaccgaagct
    34141 gactatcaaa agacgttagg tcttcgggaa aaaatttaac aatatagcca agcaccacaa
    34201 atagtagcat agcaaaggaa gacaatagca gatgttgttg tttatgtttc atgatatgaa
    34261 ttcggatatc tctctaaaat tggtttacct gcaatataca cgaaataaaa gacaattgca
    34321 aatattagcc cctccaaaag gttgaaagga atgaccattg taaatatgta gcgagcagta
    34381 ccaataaaag ctttaatatc aaagccagca aacttggcat ataagggaat agcaaagaca
    34441 tagttcatga caaccatacc aagcgttaac agccctgtcc ccacaagact agctagtaca
    34501 taggtgacca gccctttctg acgatgccaa atcaaggcaa aggcagtgat aaaaagcgca
    34561 actgctataa cattcatcgg tataccaatc aaatcattaa cgccatgatt gtttaaggct
    34621 agtctaagca aggtcctcac cgctaaaatc aagttagctt gctttagatc catcaagacc
    34681 aagcctaaca aaatcggaat gatactaaaa tcaatcttta aaaagctggc tcctggaata
    34741 atggaaaacc ccacaaacat caggcaaaag gatatggctg aaagaatggc aaccatcacc
    34801 agttgatgtg tttttgacat aaaaaattcc tccaattttg acaaattgaa agaagctcct
    34861 tcgtatgagc aggcaaaaag tcaactcaaa aacccggtct tctctcttcc agactttact
    34921 gtcggttgtg gaatcacacc acatcagctt gcgctcgcgg acttctagct gcactagtca
    34981 ccgccggtcg ggaattacac cctgccctga agacacttat agcatagcaa atttaaacct
    35041 atagcgcaag acattttttt gaagcctagc ttttccaaca aacacaagac atcaggcaaa
    35101 aaagctagat gaaagcaaca gcaagaaaaa tcactttgag gctacaaagc tctctacgag
    35161 gtaggccacc ctgtgacatg gcactagcct agctcaaggc aaaaaagagc agactagaag
    35221 aaacctccaa taacctgctc tggtattact accgttgtcc cctttacggt catagacaca
    35281 cctaaccaat gaaaactcca atcagagttt tcagattgaa gaaaaagtcc attttagacg
    35341 gttttcttca atctttttct tttaatcaaa aaaacaaaag aagtctgaaa aatactgtaa
    35401 tatcagcatt tcccagagtt ttcatgatat gatagtcaat ttctaaatgt tcaatttttc
    35461 tatcgctgat agggtttgcc tacattctga actccaatcg gagttttttc tttttggctt
    35521 tagaaaacct ttggcacagc taatggctcc aaactggtga tggtgattca tcagccctct
    35581 agggcagcgc ctttgcttct tactgctgct cacaccgcaa gctctagcag tgtagtgact
    35641 gtagctggta ggacagtaag tccttcttgt ctcacatcag gctgctatag cccctgttct
    35701 gtgtcttgat cgc
//
LOCUS       DARYJX010000023        33418 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYJX010000023 DARYJX010000000
VERSION     DARYJX010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33418
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(310..909)
                     /locus_tag="TU257_001111"
     CDS             complement(310..909)
                     /locus_tag="TU257_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0834128.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TU257_001112"
     CDS             complement(1487..3433)
                     /locus_tag="TU257_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0834129.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TU257_001113"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TU257_001113"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL0834130.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TU257_001114"
     CDS             complement(4338..5051)
                     /locus_tag="TU257_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0834131.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TU257_001115"
     CDS             complement(5486..6409)
                     /locus_tag="TU257_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL0834132.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TU257_001116"
     CDS             complement(6421..7479)
                     /locus_tag="TU257_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL0834133.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TU257_001117"
     CDS             complement(7611..8603)
                     /locus_tag="TU257_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0834134.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TU257_001118"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TU257_001118"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL0834135.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TU257_001119"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TU257_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL0834136.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(11117..11356)
                     /locus_tag="TU257_001120"
     CDS             complement(11117..11356)
                     /locus_tag="TU257_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL0834137.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TU257_001121"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TU257_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL0834138.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TU257_001122"
     CDS             complement(12069..12686)
                     /locus_tag="TU257_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0834139.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TU257_001123"
     CDS             complement(12679..13902)
                     /locus_tag="TU257_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834140.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TU257_001124"
     CDS             complement(13914..14624)
                     /locus_tag="TU257_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834141.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TU257_001125"
     CDS             complement(14624..15886)
                     /locus_tag="TU257_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL0834142.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TU257_001126"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TU257_001126"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL0834143.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TU257_001127"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TU257_001127"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL0834144.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TU257_001128"
     CDS             complement(20909..21844)
                     /locus_tag="TU257_001128"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL0834145.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TU257_001129"
     CDS             complement(21902..23161)
                     /locus_tag="TU257_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL0834146.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TU257_001130"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TU257_001130"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL0834147.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TU257_001131"
     CDS             24060..24674
                     /locus_tag="TU257_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0834148.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TU257_001132"
     CDS             complement(24755..25645)
                     /locus_tag="TU257_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0834149.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TU257_001133"
     CDS             complement(25635..26093)
                     /locus_tag="TU257_001133"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0834150.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TU257_001134"
     CDS             complement(26321..27250)
                     /locus_tag="TU257_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0834151.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TU257_001135"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TU257_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL0834152.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TU257_001136"
     CDS             complement(27972..28304)
                     /locus_tag="TU257_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL0834153.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TU257_001137"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TU257_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL0834154.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TU257_001138"
     CDS             complement(28861..30054)
                     /locus_tag="TU257_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL0834155.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TU257_001139"
     CDS             30319..30936
                     /locus_tag="TU257_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL0834156.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TU257_001140"
     CDS             complement(31234..32463)
                     /locus_tag="TU257_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0834157.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..33370)
                     /locus_tag="TU257_001141"
     CDS             complement(32498..33370)
                     /locus_tag="TU257_001141"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834158.1"
                     /translation="MKEWNDVDGKVADCYKIGNLFLYLLGKLHIRDNNILTGELKNLL
                     LQKGINSNIYKLIEYLLSENSDIEEAINMIRNDIYSYHFQCTYKLNTNIAISDDWNQE
                     LVNIISLQDTLITKYNKILDKSDEVLMQLKSEVNLGLNGLAGVLFYLSSISYDNEIIE
                     KGIDFILESLVEDSDGNRGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLS
                     ESLLVEFAQFSGLWNGMLGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQ
                     YEFRYAVSIFNQVK"
BASE COUNT        10114 a         7721 c         5921 g         9662 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atcttttaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagcacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaattga agacagatag aacaatactc
    32941 cagctaaacc atttaaccct aaattaactt ctgattttaa ttgcatcaaa acttcatcgg
    33001 atttatccaa aatcttatta tatttagtaa ttagtgtgtc ttgtaaagaa ataatattaa
    33061 caagttcttg attccaatca tcagatattg caatattagt atttaattta taagtacatt
    33121 gaaaatgata agaatagatg tcgttcctga tcatattaat agcctcttcg atgtctgaat
    33181 tctcactcaa aagatactca ataagcttat aaatattaga atttatgccc ttttgtagta
    33241 ataggttctt taattcacca gttagtatat tattatctct tatgtgtaat ttccctagta
    33301 gatataaaaa taagttccca attttataac aatctgcaac cttcccatct acatcattcc
    33361 attctttcaa tgaaatttca gagtaaatac caattaatga attggtgtta taaagata
//
LOCUS       DARYJX010000024        33066 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYJX010000024 DARYJX010000000
VERSION     DARYJX010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33066
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..618
                     /locus_tag="TU257_001142"
     CDS             <1..618
                     /locus_tag="TU257_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0834159.1"
                     /translation="IGYITLLKDEKNLSEEQKNKFVDVIYENIKYLNRLSEDFFSYLK
                     FNLNEIPLNLMDVDIKIFFSQWEEEKSLSIKDHLLILEFLDLENSKIKTEPQLLLRIM
                     ENLITNAVNYSVKGTSININVEEINGMLKISVINDVSPNLNVNWNMVTSKFYRGDLSR
                     RISNNGSGLGLTIVNDIVKHLGGNFEIGEENKRVCAKVILPYRLN"
     gene            896..1279
                     /locus_tag="TU257_001143"
     CDS             896..1279
                     /locus_tag="TU257_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL0834160.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            1387..3555
                     /locus_tag="TU257_001144"
     CDS             1387..3555
                     /locus_tag="TU257_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834161.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKNDLSFIKEEYIPKNSRFDKQKMKIYIHLNDSEWFKKSFRN
                     ISIADSKDKLNDFENVKSMSLLTSKDISLIPFENVNKEKVNGDYHVRGTEENINKFIE
                     EINQNEKLKTEVVVNPDFIVSSEFTQKQAYLYMLTIFIIFVATVFCLIIYNGMLSKEL
                     SISILLGCDELTLAIAKVLNILAIPAIVGLVLTIGIIEYLVAPSDILGFMISMKTILI
                     LVAFIIGGLISIEFILIYLKLKGINVIALLKGYRRSYHRSSFFIKTGSIVMVLYLAIV
                     SILGLTDYLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLD
                     DSGAILFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYK
                     IHENEWIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSG
                     KRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEET
                     ESEPFILYISSVYDDIVSRIDEYKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQ
                     RIDVSRLLGYGFFDIHHKKIIGNIVGYIISIIILFMVIMVTGVISDVGLFIPRDGWSM
                     SKLLISLIIGICGSFICFGIEILQLKKSERSIVLRLKEGC"
     gene            3556..4230
                     /locus_tag="TU257_001145"
     CDS             3556..4230
                     /locus_tag="TU257_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0834162.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            4227..4823
                     /locus_tag="TU257_001146"
     CDS             4227..4823
                     /locus_tag="TU257_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0834163.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVGIAMGNKCILNRTNGEKFYFPKDLIKEKQGKAIVFVVSKDGIIAKSGEIDLKENK
                     EVSIREIKEGEISLDIAAQKTDIKISIPRLDDWKVSTDEKFIKGSYEANTDSQYTLYL
                     LGKGGNLGISGTEMKGVRVIVSWEKPKDKIDSWLVFND"
     gene            5181..5396
                     /locus_tag="TU257_001147"
     CDS             5181..5396
                     /locus_tag="TU257_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0834164.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            5396..6259
                     /locus_tag="TU257_001148"
     CDS             5396..6259
                     /locus_tag="TU257_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834165.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            6332..6826
                     /locus_tag="TU257_001149"
     CDS             6332..6826
                     /locus_tag="TU257_001149"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0834166.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            6830..7240
                     /locus_tag="TU257_001150"
     CDS             6830..7240
                     /locus_tag="TU257_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0834167.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            7200..9677
                     /locus_tag="TU257_001151"
     CDS             7200..9677
                     /locus_tag="TU257_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL0834168.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            9679..10704
                     /locus_tag="TU257_001152"
     CDS             9679..10704
                     /locus_tag="TU257_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0834169.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            10670..12958
                     /locus_tag="TU257_001153"
     CDS             10670..12958
                     /locus_tag="TU257_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0834170.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            12971..13258
                     /locus_tag="TU257_001154"
     CDS             12971..13258
                     /locus_tag="TU257_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0834171.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            13263..14699
                     /locus_tag="TU257_001155"
     CDS             13263..14699
                     /locus_tag="TU257_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0834172.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            14952..15545
                     /locus_tag="TU257_001156"
     CDS             14952..15545
                     /locus_tag="TU257_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL0834173.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            15538..16380
                     /locus_tag="TU257_001157"
     CDS             15538..16380
                     /locus_tag="TU257_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL0834174.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLNSRSKDYYDLYIIYKLKDKDVNVEILREACRKTF
                     SYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAKDITFEEVLDNGIKMVEKI
                     KNEN"
     gene            16552..18264
                     /locus_tag="TU257_001158"
     CDS             16552..18264
                     /locus_tag="TU257_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL0834175.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            18268..18819
                     /locus_tag="TU257_001159"
     CDS             18268..18819
                     /locus_tag="TU257_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0834176.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            18861..19607
                     /locus_tag="TU257_001160"
     CDS             18861..19607
                     /locus_tag="TU257_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0834177.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            21428..21919
                     /locus_tag="TU257_001161"
     CDS             21428..21919
                     /locus_tag="TU257_001161"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL0834178.1"
                     /translation="MKKKEMKEVWKMKETVVLAKKEYILENEIYTPIVKESPFERQGG
                     TYRLEKMEDGAEVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLM
                     DHLIDIQEQVEDFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQI
                     IWV"
     gene            24133..31551
                     /locus_tag="TU257_001162"
     CDS             24133..31551
                     /locus_tag="TU257_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0834179.1"
                     /translation="MKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNE
                     QFPDYYNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVL
                     STLIFKDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLD
                     MKNKELRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEK
                     DKAKEERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEII
                     PFRNERELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNF
                     NPVGMSRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQM
                     SLTDIFEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWL
                     NPVSKNNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIAN
                     QFIVKVDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETID
                     KKLKSYHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYL
                     GGIPPINYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWG
                     GLSDVFDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNM
                     GFESGNILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFE
                     ETTFSNNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISS
                     SGTMDKKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDE
                     EWVKLGTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAI
                     KNIKGSYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEE
                     KVRAYLGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLF
                     REDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGK
                     VNFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADE
                     YLSGNIRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQK
                     LLEVMPKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYR
                     VEGKSIDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKE
                     TMLARSKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPE
                     IELRPHQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHI
                     VEQFGREFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPIS
                     KQRQEYELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDV
                     VTFEELGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGN
                     KGIVFATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEG
                     NGYRSKTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQIL
                     ETFSERADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNI
                     FSIWDKYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKE
                     KDKIFDKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQ
                     GNENDDVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAE
                     IKALATGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIE
                     NLKKDIEKVEPYREEKLEKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYT
                     DKKQAGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENH
                     YGEFGTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLK
                     EKTLRLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFP
                     DLTDIGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELI
                     QIKTNIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFR
                     DSKVQSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
     gene            32032..32991
                     /locus_tag="TU257_001163"
     CDS             32032..32991
                     /locus_tag="TU257_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0834180.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT        13294 a         3921 c         6788 g         9063 t
ORIGIN      
        1 ataggttata taacactatt aaaagacgaa aaaaatcttt ctgaagaaca aaaaaataag
       61 tttgttgatg ttatatatga gaacataaaa tatttaaatc gtttaagtga agattttttt
      121 tcatatttaa aattcaattt aaatgaaatt ccactaaatt taatggatgt agatataaaa
      181 atttttttta gccagtggga agaagaaaaa agcttatcta taaaagatca tcttttaatt
      241 ttggagtttt tagatttgga aaacagtaag attaaaacgg aaccacaact tttacttaga
      301 ataatggaga atctaattac aaatgcagtt aattattctg tgaaaggaac aagcatcaat
      361 ataaatgttg aggaaataaa tggaatgtta aaaataagtg ttataaacga tgtttctcca
      421 aatttaaatg tgaattggaa tatggttact tcaaagtttt ataggggaga tttatcaaga
      481 cgaataagca ataatggatc gggacttgga cttacaattg taaatgacat tgtaaaacac
      541 ttgggtggaa attttgaaat tggagaggag aataaaagag tttgtgctaa agtaatactt
      601 ccatatagat taaattaaat cgcaaagaaa acgcaagaat tattcaaaga taccgttaag
      661 tataaagcaa agagctattc tataatgtga gtaaggatag ctcttttata tttgaaagga
      721 attattaatt tgaataagca tctgtgatta taaatatata aaatggaggt ggagttttat
      781 gaattacaat aatcctcata ggtataggaa cggagattga gtagagtttt gggaaacttt
      841 attcggaaga aaaattttac aaaaaattta agtatttgag agaggagaat ttatcatgaa
      901 aaaagcattg tcattagtat tattaacagg tttgatgtta gcatcatctg taccagcatt
      961 tgcagcagaa gaaacaaact tgccatatgt tgaaggtctt ggttatgagg tggaagtatt
     1021 tgaagaagat tatactcagc caaagttgtt cagttatgat agcggatgga aaagtttttt
     1081 aggtggaaaa tggagacatg gtgtaggtag tcgatatgtt tggtctaaat acgatcacaa
     1141 taataaaaca cataaaacta cagtacaagg tgctggtggt caattctctt attcgggttg
     1201 gacaagcgct ggaagtagag cagaagcttc ttgggaaaaa gctttaagtg gtaatagggc
     1261 ttgggctgat gttaaataac aataaataaa aaatagttga acgagtttga gcggtgccac
     1321 gttgttattt tagcattgtg gcattactca tactcgctat ttttataaag ttggagatga
     1381 tacagaatga aaaaaacagt gggtatattg gcaattttac taattatagt gattggtata
     1441 ggaaagtttt tctattcaga cggcatgttt ttaaatatat tcataaaaga gtttaatact
     1501 actgtaaaca ttgtaacaaa gccagaaata gctgataaaa caataattga attgcagaaa
     1561 atagctaata aaaatgattt aagcttcata aaggaagaat atattcctaa gaatagtaga
     1621 tttgataaac aaaaaatgaa gatttacatt catctaaatg attctgaatg gttcaagaaa
     1681 tcttttagaa atatatctat tgctgatagc aaagacaaat tgaatgattt tgagaatgta
     1741 aaatcaatga gtttgctgac atcaaaagat ataagcttaa ttccttttga aaacgtcaac
     1801 aaggaaaaag ttaatgggga ttatcatgta agagggacgg aagaaaatat taataagttt
     1861 attgaagaaa taaatcaaaa tgaaaaatta aaaacagaag tcgtggttaa tccggatttt
     1921 attgtttcta gtgaattcac acagaaacaa gcatatctat atatgcttac gatttttatt
     1981 atatttgtag ctactgtctt ttgtctaatt atttataatg ggatgctttc aaaggaatta
     2041 tcgatatcaa ttttactagg atgcgacgaa ttaactttag ctattgctaa ggttttaaat
     2101 attcttgcaa taccagcaat agtgggactt gtactgacga ttggaattat agaatattta
     2161 gttgctccta gtgatatttt aggatttatg atatcaatga aaacaatact tattttagtt
     2221 gcttttataa taggaggtct aatatcaata gagtttatat tgatttatct caaattaaaa
     2281 ggaattaatg ttattgcctt attgaaaggt tatagaagaa gttatcatag aagttctttt
     2341 tttataaaaa cagggtcgat tgttatggtt ctttatctag caattgtaag tattttagga
     2401 ctcactgatt acttgagtat gagacaatac attccaactt gggaaagctc aaagtattat
     2461 gcaaatatgg cttgtgcatg gtcttggagt tatgaaaaag atgatgataa gttccatgaa
     2521 attgttattc caaagctgaa taacttatgg aatagtttgg acgatagtgg agcaatatta
     2581 tttaatgccc caaacgttag aaaagaggga atgaatgatg atgaggagta tctaaatcaa
     2641 caaccttttc aaggtaatta tgcctatgta aataaaaatt atttacatat tgctaatctc
     2701 ttagataaag atacgaataa aatagaacaa tataaaatac atgaaaatga gtggattgtt
     2761 tttgttccag aagatgttaa aattactgaa cttgacaaag aaaaaattca cgaagatcat
     2821 atttttcaaa atataaaaaa acaaggtaca attatagaaa catatgtaag gctgaaagat
     2881 aatcaaagtg tattttcttt tgatagtggc aaaagaattg atgaagcaaa cttgaaaaat
     2941 tatgttttgg tagcagtaaa tgggaaagaa ttactcccag atcacggaat caaactatca
     3001 tctttagtaa atgggcagct acatccatat gttaaagagc ctagtagggc atacgagagt
     3061 ttgaaggaca taattgaaga aacagaatct gagccgttta tactctatat cagctcagtt
     3121 tacgatgata tagtttcaag aatagacgaa tataagatgg aggcaagtat atatgttatt
     3181 ggtctcgtct tatctattgt tattttagca acgttattaa aaatagataa agaaacatat
     3241 ttttataatc atggacaacg aatagatgtt tctaggttgt tgggatatgg attttttgat
     3301 atacatcata agaaaattat tggaaatatc gttggttata tcataagtat tattatttta
     3361 tttatggtta ttatggtaac aggagtaata agcgatgttg gactgtttat accaagagat
     3421 ggttggagta tgtctaaact tttgattagt ttaataatag gtatttgtgg aagctttata
     3481 tgttttggca tagaaatttt acaactaaag aaaagtgaaa gaagcattgt acttaggtta
     3541 aaggagggtt gttaaatgca aaatgaaaag gaattgcaaa taaccttaag aaatgtctct
     3601 aagaaatatg gagaacacag tattttggaa aatattagtt tggatattta taaaggagat
     3661 tttgtttgta tctttgggaa aagtggagga ggaaaaacaa cacttttaaa tataattggg
     3721 acattagaaa attatgatag tggtagtgta acctgttttt caaatcgaga tcctataaaa
     3781 gctcctaaag taggagagct attacgcaga gaaaaaattg cttatttatt tcaaaatttt
     3841 gctttggtgg aaaaaatgac ggttgaggaa aatatgatgc ttgctgcaaa atacaatcaa
     3901 gaaaaaaata agaaaaatct tatagaagct gccttgaata aaatgggcat ttcagacaaa
     3961 ttaaaatcga aggtttatga actttcaggt ggagaacagc aaagggtagc tcttgcaaga
     4021 aatatgataa aaccgtttga aattatgttg gcggatgaac cgacaggttc tcttgattat
     4081 gagaataaaa aaattgtaat cgatacactt attagattaa atgatgaagg taagacaatc
     4141 gtagttgtaa gtcatgataa ggattttgaa aaagtagcac ataagaatta tattattgaa
     4201 aagtcagcta taagggaggt gttgagatga aaaggaagat tgctttatta gtaccggtta
     4261 tagtactgtg tatttgtggt ttattctttt acatgaacag aaatagtgat gatattgatg
     4321 ttgcatttac agtaaaaaat gaaacaaaag aaaaaataga tacagtgggt attgcgatgg
     4381 gaaataaatg tattttgaat agaacaaatg gagaaaaatt ttattttcca aaagacctaa
     4441 tcaaagaaaa acaaggcaaa gctattgttt ttgtagtatc taaagatgga atcatagcaa
     4501 agtcagggga aatagattta aaagaaaata aagaagtaag tataagggaa ataaaagaag
     4561 gagaaatatc cttggatata gctgctcaaa aaacagatat aaaaattagt attcctaggt
     4621 tagatgattg gaaagttagt acagatgaaa aatttatcaa gggctcttat gaagcaaata
     4681 ctgattcgca atatacatta tatttattag gaaaaggcgg aaatttaggc atttccggta
     4741 cggagatgaa aggagtacgt gttattgtaa gttgggaaaa accaaaagat aaaatagata
     4801 gttggcttgt atttaatgat taaaaataca atatttgtaa taaaagttgt aaaataataa
     4861 tttattgtta ggggaggatt tatactaatg tgtaaatcct cttttttata taaagcataa
     4921 aataatgaaa gtgaaattaa gctataaaat attatgaaaa aagatacttg gaagtgtaaa
     4981 tgtaagatgt atatttctaa aaataataga cattaattta aaagagagat gggataaata
     5041 aaatgaaaaa tataataaaa tcaataagga taagaagtcc aactttaaga aaattgaata
     5101 gcaaaagttt aacgattgga agagaagatt tccagtcgtt tttttatgaa aataagtaaa
     5161 ataatgagga ggaataaatt atggattttt ttgtacaggc agtaaatgtg cttaaaattt
     5221 tggttatggc aatcggtgca ggacttggtg catggggagt tatcaactta cttgaaggat
     5281 acggatcaga taatcccggt gccaagtcgc aaggaatcaa gcaattgatg agcggtggag
     5341 gaattgtttt aatagggctg aaactaattc cgctacttgc taatgtcttg agataatgtt
     5401 tgatttattt ggaaagatag aagagttttt caaggatatt atgattgata ttattaaaga
     5461 taatctttct gcaatgcttg tggatattaa tgataaagta ggaaccgttg caggagaagt
     5521 gggaaagact ccgagttctt ggaactcgga ggtcttcacc ttcattaaat caatcaatac
     5581 caatgttgtt ttacccatag cagcgataat tctaaccgca atactttgca tagaactgat
     5641 tcaggtggta atgagaaaaa attctatgca cgatacggat acctttgaat tttttaagta
     5701 cattattaaa atgtggatag ctgtatggct tgtgtctcat gcgtttgatt tttcaatggc
     5761 agtctttgat gtggcacagt ccatgatagg aaaggcagca ggtgttgtgg ggacaagtgc
     5821 gaatatcaca ccgggaaatt ttgatgctat ggtagaagcc cttaaaacaa aggaacttgg
     5881 aacactcatt gggattgcac tggagacggg attagttaaa ttttctttaa cgattctatc
     5941 aatcttaatc actgtaatcc tatatggaag aatgattgag atatatatct attgctctgt
     6001 tgcggcaatt ccattttcta cgatgggaaa taaagaatgg tcaaatatcg gaacaaacta
     6061 tataaaaagt ctatttgccc ttggacttca gggacttttc atcctaatat tttttggaat
     6121 ttacgcagtc ttagtcaaaa ccgtaaactt tacggatatc cacacaagta ttttacaggt
     6181 attggcatat ggattgattc ttggagtaat gatgatgaaa tccggaagta tagcaaaggc
     6241 gattttaaac agtcactaaa ggactttagt tcaaaatgag caaaagttga tgaaataatc
     6301 agaacaaaaa atataattat tggaggtaag aatgaataaa ataaataaaa aaacaaggat
     6361 tttgatagga gcaggctcag ccctttctat cgggacaatt attacagtgc tattaaaaaa
     6421 gaaaacgaaa aaattatccg atcttgaaga agatgatttt gactttgatt ttgatgaaat
     6481 agaagaagat tcttgtgtca acgataaatt tgctacagaa aatgataaag atgatacagt
     6541 aaaaggagaa atagattttt tagtagatga atcaaagacg gagaacgaaa agcaagaaga
     6601 gtttagagat ttatcggtaa aggtaatgga tcttcttcta aaagaagtaa tttcaatgag
     6661 tgaaacctta aatttggtaa aaagagatat tgatagaata ggtgaagtaa aagcattggt
     6721 tgaagaactg gaaaactgta aagaagaaat tatctcactt tgggagcaca tggaaaagtt
     6781 atccgattta agagaagaaa ttaccggcaa aaagaataga ggttaggcta tggcttatgt
     6841 aaagatacca aaagacctta caaaagtaaa aaccaaggta gccctgaata tgacaaaaag
     6901 gcagcttata ggttttagca tagcagggct tatcggtttt cctgtatata tgctgtgtaa
     6961 aaattttctt agtacagata tttccatgat tataatgagt atagtagttc tacctgttct
     7021 ttttgtaacg ctttatgaaa aggacaattt accttttgaa aaacatttag catatatcct
     7081 caggtttcat aaaagtaaaa agatcaggct atataaagcg aggagcattt atcatacaga
     7141 gagagcaaaa aagcaagata taggaaataa aaataaggca agcggaagga ggaaaaaagt
     7201 tgaacaaaga caaaagaaaa aaacaggaac aacgaattaa aaaggatgag ttggagctta
     7261 ggaaaaatag aaaggagcta tccgaactta aaaaaacagg aaagaaaaaa acaaagtcta
     7321 aaacaaaagg gaaatcatcg aagaagaatg ggtggtttcc tttttttatg aaagaggaga
     7381 aaaaagaaac cgtacaggat accattccat ataagcgaat gttaaaagac gggatttgtc
     7441 aaattgaaaa gaataagttt aataaaacca ttcgattttt ggacattaac tatcgcttaa
     7501 tggaagaaat agaccaagag ggaatatttt cggaattttc ttcttttcta aatttctttg
     7561 actcatctgt ggaagtggag ttcagctata tcaacagtat cggagaaaat gaagaaatca
     7621 ataaactgat tgatattaag gaaaatatag atgattttaa tgaaattaga aacgaatata
     7681 gacaaatgct cttaaatcaa agcagcaaag ggaataatgg attatcaaag agtatgtaca
     7741 ttacctttac catagaggcg gaggacttaa agcaggcaaa aagtagatta gagcgaatgg
     7801 aaatggatgt attaaacaac tttaagcaga tgggagtgaa agcctatgtg ttagatggag
     7861 aggaaagact taaaacaatt catgacattt taaatccaaa tgataaactt gttttttcct
     7921 ttgaggattt gaaatacagc ggactgacga ctaaggaata cattgtacct ccgtctttta
     7981 acttttccaa gccgacgtat tttaagacag gagaagtctt tgcggaagta aattttttac
     8041 agcttttagc atcagatatt aaagatgaga tgttatcaga gtttttggca ttggaagaaa
     8101 atatgattgt tacttttcat atcagagcaa tcgaccagat ggaagctatt aaacatgtaa
     8161 aaagaaaaat aacggatttg gataagatga agcttgagga aaacaaaaaa gctattcgtg
     8221 cgggatatga tatggatatc ttgccaagcg accttgtaac ttatggtgca gaggcaaaga
     8281 acttgctatc agaactacaa aaccatgatg aaaagatgtt tctcataaca attttattta
     8341 tgaacacgag taaaagtaag gggaaactcg ataatacggt atttacctta aagtccattg
     8401 caaatagaca taattgtagt ttgaaaaacc taaattatag acaagaacaa gggcttgttg
     8461 caagccttcc acttgggata aatgaagtgg agatagaacg aggacttacc acaagtgcag
     8521 cagctatttt tataccattt acaacagaag aactctttat caagggagaa agcctatatt
     8581 acggactaaa tgcactaagc agaaatatta ttatggcgga caggaagaaa ttaaagaacc
     8641 caaatggtct aatcttagga acaccgggtt ctggaaagtc ctttgcagcc aaaagagaga
     8701 ttactaatgc gtttttgatt acagatgatg atattatcat tgcagatccg gaagcggaat
     8761 attctccgct tgtagaggca ctaaaaggac aagttatcag aatttctccg atttcaaaag
     8821 actatgtcaa tccactggac atcaatattg actatgcgga tgaagataat cctttgtctt
     8881 taaaatccga ctttattttg tccctatttg aattggtggt tggagaaaag aaattaagtg
     8941 cagaagaaat ttctgttata gaccgttgtt taccaatttt atataaaacc tactttgaaa
     9001 atcctgtgcc ggaaaatatg ccaattttag aggatttata taatcttctt caaaaacagg
     9061 aagaaatagt aggaaaaaag cttgcagtag aaatggagat ctatgtaaaa ggaagtctta
     9121 atgtatttaa tcatagaacg aatgtagata caaataacag agtggtttgc tatgacatca
     9181 aagaactggg aaaacagctt aaaaagatag gaatgttagt tgtgcaggat caagtttgga
     9241 atagagttac aattaacaga gcaagtaaaa aagcaaccag atattatgtt gatgaatttc
     9301 atcttttgtt gaaagaaccg caaacagcca attattcgat tgaaatctgg aagcgtttca
     9361 gaaaatgggg tggtatgcca acaggactta ctcaaaatat caaagacctt cttgcaagcc
     9421 cggagattga aaatattttt gataatacgg attttatttt aatgcttaat caagcaggaa
     9481 cagataggga tattttagcc aagaagctca atatctccaa gcatcagctt tcttatgtaa
     9541 caaattcggg ggaaggagaa ggacttatct tttatggaaa tacgattgtt ccttttatcg
     9601 atcagtttcc aaaaaataca aaactatatt cactaatcac aaccaaacct gaagaagtaa
     9661 aaaaggcagg tgaataggat gagtgtgagc agaagtaaag aggaattcat caaagaaaat
     9721 acaaataaaa ttatttgttc ggatgcactt gaaactttaa gaaaaattcc agacgaaagt
     9781 ataagctgct gcattacatc tcccccatac tacaggctca gaaactatca taaagaaggt
     9841 cagataggaa gagaatctac agtagaagaa tacttggata gattgttaca ggtatttcgt
     9901 gaagtaagaa gagctttaaa aaaagaaggt acttgcttta tcgtaattgg agattcttat
     9961 gctgattcag gaggtggaaa gggacaatac attgatccta aatatccaaa ggcaagaaat
    10021 ggaagtaacg ctttagctac agaaaatatc tcagggtaca agtcaaaaga tttaatggga
    10081 ataccttgga gattagcgtt acttctaaga gaggatggtt ggtatctgcg ttctgatatt
    10141 atctggcata aggaaaatgc tatgccggag gcgtgtagag atagacctac tcgttcctat
    10201 gaacatattt ttttacttac gaaatcacca aaatactatt atgactatga tgctatggta
    10261 gagccgatga aagaagtcag taaaaaaaga tatgtaagag gaagaaaatc ggataataaa
    10321 tatctgaaag aaaattccgg agcaaagttg caaaaaatca atgaagcaag aaaatatgga
    10381 gaatataagg gcgataatgt cccgcagttt cgtaataaaa gagatatttg gactatcaat
    10441 accacatctt ttagaggcaa tcattatgca acatttccac cgaaacttgt tgagatttgt
    10501 atgattgcag gttgtcctaa aaatgaaatt gtacttgatc ctttcattgg aagtggaacg
    10561 gtcggatttg tggcacttcg tcataacaga aagtacattg gaattgaatt aaatgaggag
    10621 tatgtaaatc ttgcaaagaa tagaatcagt gaggaggtga aaaaatttaa tgaagaacaa
    10681 aaacaagagg tacaaaaaga atagagaaaa actcttaaat caagaaatac agtctttaca
    10741 atctcaaact caagataatt atgaaacagg atcctcaaaa aatcagaatg aaaccttgct
    10801 gaaagacgaa acttacgata agaaacaatt tttatctgaa aagaagttat ccaatcattt
    10861 ggataataga catataaata attattcgga tagaactata tcttcttatt gcttgtcgga
    10921 tacgggaaat ataaatcaaa ataggtcttc ctttcaagct gaaaaacata aaaaaaagat
    10981 gcaaaagcag ataaataaat ttcaaaaggg agaaaaggaa gtctacgatc ctttatcaaa
    11041 agatatggat aatgatggtg taatagacag gtatgatgtg gattttaggg atagcaaagt
    11101 atcatatcga actcttacag atgatgaaaa gtatgataat aaccaaaatg ataaaggaaa
    11161 aaattataat gactatgtaa aaaatccaaa atctaagaat aagaggtata aaaattatgt
    11221 aaaagacaca ttttctaagg aaagaatgaa atcagaaaac cagaagaaat atgtgaggag
    11281 caactttgat gatgaagagt tcacaagaaa taaggatacg aaaaataatt tatttcagga
    11341 cgtaaataat aaaagaaaaa ctaccgataa aaattcatca cgaaaaagaa aaggaaaatt
    11401 tgaaaataag gaaaagaaaa tatccaagtt acagcagaaa aagcaaagac aagagcaaaa
    11461 actgaaaaat aagggaattg acgggaaaag tcaaagtgct aaaagtgcag taatagcaac
    11521 gggtatggca aagaggtatt tggaaagtgg aaaagaggac aatgccggag taggtactgc
    11581 ttataaggtt acagatcagg tcgaaaatat ttcaaggaaa atatattatc atggaaaaaa
    11641 gaaaaattta aaaaggcaaa aaaagataac aaaattaggt aaaagcattg ataaacagga
    11701 gaagaaactc ttttttcaaa agaatatgga agagatgaaa aaaagcgtgg attaccaaaa
    11761 tacctcaagg ctcagacaat tctttaagag aaggcaatat aaaaatcaga ttcaaaagaa
    11821 gtataaagat agtgtgaaaa acagaataaa aaaatccttt atagagggca gtaaaagatt
    11881 tggcgaattt gtaaagggca gagggaaaaa gataatattt ctatcacttt tagcggtagg
    11941 aatatttttt atgttatttc aggctgggag catgatgatg aatatgggaa cgggaatggt
    12001 aagtaatact gtttcaacca cctacttatc atcagaagac accttaaaag aaatcaatca
    12061 gaggttttca tctttggaac aggctttgca agaagaaatg gacagtgtgg aggaaaatca
    12121 tccgggctat gatgaatata ttatcaaagg aaaagagaaa attggtcata atgttcatga
    12181 actcttgtca tatatcacag cccgttatgg aattgtaaag aatatttctg aagtagaaag
    12241 tgaactaaaa catctgtttc aaaaaatgta tacgctgact tataaagaag agattgaaat
    12301 cagatataga actgttacat ccagctatac ggatgctgat ggcaatgaac atactgaaag
    12361 tcatgaagag ccgtatgagt ataggaaact cattgtaacc ttagaaaaaa gagagatgga
    12421 cggaattatt agagaagcat ttaagcgtta tcctaataat ttggcacact atgaaacttt
    12481 atttttgaca caaggaaata tgggagaagt atttggaaat attgacctta taaattcaaa
    12541 tggtggaatt ggtggtggta aagagtatga agcatcaagt gaagtgcaaa agaaaatagt
    12601 gaatgccgct tatattacac catctccagg agcaggttgg tgtgccatgt gggtatcaca
    12661 ggtctatcaa aatgcaggac ttggatttat tggaggaaat gcttgtgata tgtatcgaaa
    12721 ttatactttt acttctgata ggtcaaagtt aaaggttgga atgcttgttg cagttgaaag
    12781 tagcagtagt ggtagcagtt taggtgttac ctatggtcat gtaggtattt atatcggaga
    12841 tggaaaagta atggataata tcggacacat aagagtaact accctagatg attggattgc
    12901 aacattttgc aaacatcacc ctgtaggttt tggatttcca ccatcagtac aaaaataagg
    12961 agggaatatt ttgaataaaa aatatagaaa aaatatagaa aagcaaaaag atattcagaa
    13021 aaaaatagaa gaactccagt taaaacagga gatgttaaaa gaagaacagg aagagatgga
    13081 aaatattgag gttttaaagg aataccgaag tattgacatt tctattgacg attttttaga
    13141 aatgatgaga cgttataaaa aagaggaaaa acaagaaaaa atgaagttac aggaaatgag
    13201 aaatacagaa aatcataata atatggagga aaatcatgaa aatcaaatgg aagaataaaa
    13261 aaatggcgat aacattgtcc ggagtaatct ttttgatact tgctttactt ggaacaatgc
    13321 ttttcaatca ccagattgtt tttgcacaag gtagtttaat cccgacactg attagtccca
    13381 cagaagtttt agctcaaact aaagtggagg ttaagataaa atatatattt aaggatgaga
    13441 gtgtatataa ggaagaaata attgaagtag aaaccgggca agttcttgac agtggggacc
    13501 taccaatgtt agaggataat atgaaattta ttgacgaatt tttgttctat aaagtaaagg
    13561 gagacggtac agatgagatt atccgtaaag tagaaaaaat tacagttaag gataaagaaa
    13621 ttcagacaga agaggaaaag ccaaaacagg acgaaagcac tgagacggaa gataaaaaaa
    13681 cagaagataa gggaacacag acagagcttt ctaaagatga tatttccaaa atggaaaaag
    13741 aggcaaaaga gcttcaggat aaacttgata aattaaatgg tgaaatcagg gataaagaca
    13801 aactaagcga taaacagaaa gaaaaaatca aagaccttga agctgagatt gaaagtctga
    13861 aagaaaaaat gaagaaagat aagggaaata aagacttatc agaagatatg aaaaaggaaa
    13921 tagataagct gacggaaaag gtgaaagagc ttgagaaaaa gccaactgaa acaaacaaag
    13981 ctcctgtaac atcacagtct gttacaccga ttagtcctat ttcagggatt aagacaagct
    14041 caggtatttc ttctcaaaca ccacagagtt ccggtaaagg ttcatctgat gcagtaagct
    14101 ccggcaatac tacaaaagat acaggtaaaa ctgaatcaaa ggagaaagaa aaggaagttc
    14161 gctatcccaa taagctgaca ccgaaagctc ctgctaataa cagtagtcag gattcatcaa
    14221 tggacggtgc aagtagcaat gtaaatacca ataagggtgt ggcttcagct ccgtcaaagg
    14281 caagaggaac tgttacagaa aataaagata atgcgaataa tgattatcca attcatcatg
    14341 gggatagcag cgataacaaa gaagcagata agtattcagc agatgcaaga caatttatta
    14401 ctttccagac aaaatccgga aagacatttc atttaatcat caatcacgat gagcaaagtg
    14461 aaaatgtaat gcttttgact gaagtatctg aagatgatct tctgaatatg gtagagaaga
    14521 aggaaaaccc gcaagaagaa atcaaaaaaa tggaagaaac ggtaccggaa agcgaagtaa
    14581 aaaaagaaga gccgaaaaag gaagaaggta aaggtagcgg ctcatatatt tttttaggaa
    14641 tcatcgttct tgcagtagtt ggagcaggat attactttaa aatctacaag aaaaagtagg
    14701 aagatgatga ttatgatgaa gatgaggaag aatatgatga atttgaagat gagtatgaaa
    14761 aagaggacga tacagaagat ttggaagaaa cagtagaaga acagcataac atagatgata
    14821 tggcaatcga ctcttatgat gaagaagatg aggaataaag ttataaaaag agaaatgtaa
    14881 accctgatgt tgcgtttaca cttaaaaaat ggtataatgc aagtgtaaac gcaacaaagg
    14941 gggtggatgg gatgaattat gaaaataaaa ttgaaaaata tttgaagcaa tcaggtggaa
    15001 ttattacaac agcatactgt aaggaaaata atataccgac gatatatctc agtcgactat
    15061 tgaaagatgg gagattgtca aaagtaagaa aaggaattta tataacgaaa gatggggatt
    15121 acgatgagta ttatttcttt caacatcagt ataaaaaggc gatattttct tatgaaacag
    15181 cactttacct gcttggacaa acagataaaa ttccttggag tatcgatgta accgtttata
    15241 acggatataa atttaatgaa aaaccgaacg gtttcaatgt tcattatgta aaaaaatcaa
    15301 tttatgactt aggggtaacc caaaaaccta caatgtttgg aaataaagtt aaggtatatt
    15361 catatgagag gacactctgt gattttattg ctcataaaga agaaatggat atagaggttt
    15421 atgtaaaact tattcaatca tattcctctt ataaagaaag agatatccat tccctctatg
    15481 acattgcaat gaaaatggga attgaaaata aagtaagaga ggttatggag gtggcttatg
    15541 aataaagcta aattaacggc tctttgccat aaagttagta aagaagtcgg tctttcgttt
    15601 aatgctgtta tgttatatta ttttttagaa agtattttaa aaaaattagc aggaagcaaa
    15661 tatagtgaac gatttatttt taagggcggc tttttgttat caagtgtagt tggaattgat
    15721 tcaagaagta ctgtagatat agactttctt ttgagaaata tgcaactatc agaagaaaat
    15781 attgttcaaa tgctgaacga aactttaaaa ccggaagaat tcgacgatat tttttatgaa
    15841 ttgcaaaaca ttgtgccaat caaagaagaa gatcaatatg gaggatttcg tgcaaatatc
    15901 ttatgtaaaa tggaaaatat aagacagatt gtaccacttg acattgcaac aggagatgtt
    15961 attacacctc atccgataga ttataagtat gtgagttctt ttggagaaga agaaataata
    16021 atcaaggctt atccgataga aactatgctt gcagaaaaaa tacaaactat ttatgcaaga
    16081 ggatttttaa atagtagaag taaggattat tacgatcttt atattattta taaattaaag
    16141 gataaagatg taaatgtaga gatattaaga gaggcttgca gaaaaacttt tagttataga
    16201 aaaacagaat ttgacatagg taaaatcata gacttactgg aaaaattgaa aataaatgaa
    16261 gcctttttga aaagatggca agcttattca agaaaaaatc tgtatgcgaa agatataact
    16321 tttgaagaag tattggacaa cggaataaaa atggtggaaa aaataaagaa tgaaaattag
    16381 catataacgg ttttacaatg aaaagaaggc gtcaaacatt tttttgtaag ttagttccca
    16441 aacaggaaaa tggattaaaa aatagaaaat gaaatatata aaactttaaa agacaattgg
    16501 agaaatgcaa actctgattg tcttttttca tgtagaaaaa aggaggaatt tatgcaaaca
    16561 ctggtgataa gtgaaaaacc gagtgttgca ataagcatat caaaggtgct tggagcaaca
    16621 aaaaagaaag acggatataa tgagggaaat ggatataggg taagttggtg tgttggtcat
    16681 ttaattcaga tggcaaatcc ggatgcttat gatgaaaagt atgccaagtg ggatatggct
    16741 gatttaccga ttattcccaa ggactataag tatgaagtag caaaggcaac caagaagcaa
    16801 ttcaacatcc ttaaaaagct gatgaatgat aaagaaattg atacggttat aaatgcttgc
    16861 gatgcaggtc gtgagggaga gagcattttt agacttgttt ataatcaagt gaattgtaaa
    16921 aagaaaatga aacgcctttg gatttcatct atggaagata gtgcgattaa agagggtttt
    16981 gatcatctaa aagacggaaa gaaatatgac aatctctttg aatcggcaca ggcaagagcc
    17041 attgcagatt ggttagtcgg aatgaatatt agtagacttt attcctgctt atataatcaa
    17101 aattactctg tcggtagggt gcagacgcca actcttgcca tgattgtaaa acgagatgac
    17161 gagatagcaa actttaaaaa agaaaaatat tatactgtag agctatctat ggacggtttt
    17221 atactttcca cagacagaat tgatgataag gtagcagcag agcagctaat caatttagtt
    17281 ggtgataaga ttgaaattac cgatgtcatt caaaatgaaa agattacaaa gccggattta
    17341 ccttttgacc tgacaacact tcaaagagag tgcaataaat attttggata ctcagctaag
    17401 cagactcttg attatgctca aagtctgtat gagaagaaac ttattaccta tccaagaaca
    17461 gacagtagat gccttactga agatatgatt acaagtatga taaataacat attgggacaa
    17521 aatgactttg atacagggcg tattaaggtc atttttaatt caagcaaggt aacggatcat
    17581 catgctatta taccgacagt aagttcaatg agtgaagatt tattgagtat tccggagagt
    17641 gaagcaaaag tgtatggact tatttttaat aagttacacg caagtgtggg ctatccttta
    17701 atcgagaata caacaaagat tgtagtgact tttgacggct ttaaatttac aagttccgga
    17761 aaagtaatta aggatgaggg gtttactaag tatttaaagg aatataagac gaaaaagaat
    17821 gaagatatag aacttccaaa tgtaaatata ggtgatagtc ttaaaatcaa ggataaagaa
    17881 atcaaagaaa aatatacgca acctccaaaa cattttacgg aaaacacctt attaaaaagc
    17941 atggaaacag caggaaatga cgctttaaaa aaaggtattg aggttgaaag aaagggtatt
    18001 ggcacacccg caactcgtgc agggattata gaaaatctaa tttacaaagg ctttattcaa
    18061 agagataaga aaaatcttgt agctacacat aaaggaatta gtcttataac aattgttgca
    18121 gacaacttta aatctgctga aacaactgca aagtgggaaa tggagttgtc tgatatttct
    18181 caagggaaat cttcaaagga agaattttta agaagagtag aagctgagat aagaaatgaa
    18241 ttatcccgtt ataaaaagga ttagtctatg tttgatactc taataaaatt tagtaaagac
    18301 agagaaaaat tggattttta tgccacagat aaaagggcaa ttcatgaact tttaaaaaga
    18361 gagcagtttc tatctcctat ttatgagccg gcttgtggaa tggggcatat cggaaaagtt
    18421 ctggaagaat acggttataa ggtaaaagct acagatattt gttatagggg atatggagaa
    18481 gaaagagaag ttgatttttt tacagtaaca gaaaatatat tggatatagt aaccaatcca
    18541 ccatattttt gtgcaagtga gtttttaagg cacgctcttg aaatatcagg acctaaagta
    18601 aagatagcaa tgctatttcg gttggctttt ttggaaggtc aatcaagata tgaattattt
    18661 aggaaatatc ctccaaagag agtatatgta ttttccaaaa ggcttaattg tgcaaaaaac
    18721 ggagaatttg agaaatacaa aagcagtgct attgcctttg cctggtttat atgggaggtg
    18781 ggatacaaag gtattacgga gttaaggtgg attagataaa aggatggaat aaaacaactg
    18841 aaaaaacgaa ggaggatagt atggataaga atgaagtatt acaatcacag gaaaatcaga
    18901 caaaggaagt tatgcaggag attaaagagg aatataccaa aacagctgac tttttagaag
    18961 aacatataaa tcagcagctt gtgattgcta aggaaatgaa agaagagatg caaaataagg
    19021 actttgatgt aaatatcaaa gaattgaaag cactcaaaga agaaatcacc ggattaaaag
    19081 ctgaaattaa acgattaaac gaaatggaaa atataacttt tggttcattg attataagag
    19141 atatcaaatc tgtaggaaat acccttatca atttacagga aaaagcggta ggaagtatta
    19201 aacatctgta tgataatatg aaacatcagc tttcctataa ccttaccaaa gcacaggaaa
    19261 aatttgtaca gatgaaaata ggaattgtaa aaggattggt aaattccatg caggatttta
    19321 tcaaggatca acaaaagaaa ctggatagtt gcttagcaaa acttgataat ctatctaaag
    19381 aaattcaaaa agatgaagaa aaactggaaa aaggcaatct gaataaagag aaaaccctga
    19441 taaaaaaaag ggaacaaagc atagaggaaa aagaaagtca aaaggaaaag atggagaaaa
    19501 aaccgtctgt gctaaaaaaa ttaaaggaaa atcagcaaaa aatcaagcag gaagaaaaga
    19561 ataaagatat aaaggcactt aaaaaagata agggaatgga actataaaaa agaggtggta
    19621 gttatgaatg acctcataaa aaactatgaa aatattcctg atgagatgaa aaaagagaag
    19681 cgttggtgcc tatataaaat cattcaaaga gacgggaaga acacgaaact tccactaatg
    19741 ccaaataaag agccggcaaa atcaaatgat aaagctacat ggaatagcta tgaggattgt
    19801 atcatggcat taaaacataa tgttggcgaa gggcttggct ttttcttagg agatggatac
    19861 attggaatag atattgataa agtaagtgat gacattatgg agtacaatac gaatcatcat
    19921 gtaagctcta tgacggctga ttttttaaga gaagtttcca cctatgctga gatttctcca
    19981 tcgaaaacag gactacattt tattggaaaa ggagaggtgc cgggagaaag aaaaagatat
    20041 aaaaatcttg aaatttatga taaggatagg ttttttacag ttaccggtaa tgttataaag
    20101 gatagagata ggagcaaaat agaaagtatt gacagtgagc taaagccctt atatgaaaaa
    20161 tatatgccaa agacaaataa aattagtgct gaaaataaaa gaagtccaac ggttacttct
    20221 tacaatgggg atcaggacat attagaaaag ttatttgaca ggggatattt ttcatatgca
    20281 ggagaagatt taagacaaat ttactatggt aattatgaac gctattttaa cagccaatcg
    20341 gaggctgatt tttttatgct acaaaggctg ctttactata caggaaatgt agaaatggca
    20401 atatcattta tggaaagtag cggactgaaa agagaaaaat ggtataaaag acgaggcaat
    20461 accgattata tccactatat tgcagataag gcgataagct ctatcaatca attttatgat
    20521 tgggaaaaag tatatacatc aaaggaaaaa atagaagaaa aaagatatga aaataagaag
    20581 aaaaaggagg gagatacagt gccaagatat gaatttgatg aagtcaaaca gattcttgat
    20641 tttgcaaaag aagaatttaa agaaaatata gacaggtatg aaacttatct caaagtgatg
    20701 ggaaataact ataaatatcc gtactttaac cagcttagca tatatacggt aaatgaaaat
    20761 gcaactgctt gtgcagaata tgactattgg aaaagtatag gaagaaatgt aaatagagga
    20821 gaaaaaggaa tacctgtttt agacattgaa agagagaaga taaagtatat ctttgatgca
    20881 agtcagacag taagtttaaa tcacaacatt tctgaagtaa agttatggga atatagcaat
    20941 aataagcatg tagctgcctt agatactctt atcgatgttt tcaaagaaaa aaacagtaac
    21001 cttatatttt ctactgaaga taagataaat acaatcgttt cactatatac aaagcaatta
    21061 ctaaataagg tacttaattc tttaagtgat gaaactttaa aggaaaataa gaaagtacaa
    21121 attcttcatt ttttggaaga atctgcaaaa gtatcggtat atgagagaat gggagttgca
    21181 ttttccggtg atatagaaaa attagagatg ctttcaaatg tttcaagtat gcaggatatt
    21241 gacagattac ttttctttac ttcaaacaat gtaaaaagaa tacttatgga tataagtaga
    21301 gaaatttcaa aagtggaaga aagagaaaaa atttcagaaa ttcaaaaaag ggagcagaca
    21361 aatagtattg cggagcgtta tactaatgtt acagatgaaa ttaacggaaa taccgaaatt
    21421 atagaaaatg aaaaagaaag aaatgaagga ggtttggaag atgaaagaaa ccgtagtatt
    21481 ggcgaagaag gagtacatcc tagaaaacga gatttataca ccgatcgtaa aagagagtcc
    21541 attcgagaga cagggaggga cttacagatt ggagaaaatg gaggatggag cggaagtatt
    21601 agttccgaat atgaaaatgc cggagaaaat aaacgcaagc aaactgaacc gatttggcaa
    21661 ggagagactg aaatatctca aagaggagaa acaagaggaa tatcagatta tgctgatgga
    21721 agaaacttta atggatcatt tgatagatat tcaggaacaa gtggaggatt tcctgaatat
    21781 agaagagccg aggatgaaag aagcttggaa aatgaccaca gaaatgcagg atcaggactt
    21841 tctgaaatac acaggactga agaagaactt ggatatgaca ctaacaaaaa tggctatgga
    21901 acagatcatt tgggtataga tgagtatcgt aaagaaaata tacagaagat agaacaaaat
    21961 catgtagaaa atgaggaaaa agaagtcgag aggacttctt tttcttttgc tcaaaatgta
    22021 ggagttcaag gaagatttga attaccaatg cagcaagaag agattggtgc tgttttaatt
    22081 catggaggaa atgaggataa tttacattta aaggttttag ccgaatattc taaagaaaaa
    22141 agcatggaag aattagctga ttttcttcaa aaaacttttc aaggaggaaa tggatatgaa
    22201 ctaaatggaa ataaggtttg tgcttggtat gaaatggacg ggatacattt atccaatgat
    22261 gtttcctcaa gagaaaatcc tatgcagatt ttaccatgga aagatgcagc aatacgcata
    22321 ggagaattga ttgattatgg aaaatacagt acaaatgtgg aggtagcaga agccttttct
    22381 tttgaaagag cagaactttc tgaaaagctg tggtttttaa aaggagatct aagtgatgag
    22441 gtaaaaaatc agtttttgcc aattctaaat gaaaaacaaa gaaacggata tcctgaaaaa
    22501 acagagtatc ttacaaaaaa attggaagat aaagagttta gagtgaactt aaaagaggag
    22561 tatatagagt tttttaaggc gtataaggag aactcgaatg ttttaagatt tcataatcat
    22621 gatttagatg atatatcaaa acgattagat gatttggaac tgccaagaaa agaatttacc
    22681 tcaacactta tagaattacc agcaatacag ggatttatca cagaagatga aattgataga
    22741 tatttaagca gcggtagcaa tgtatccggc ggaaaagaaa gaatatataa cttttttagg
    22801 gaagcccata ctaccgaaga acgagcaaat tttttaaaag acgagtacgg aacaggagga
    22861 cagactcatg ctttatcaag ggcaagagga agtagtgagt ggcacgatgc taaggggata
    22921 aaacttgaaa aagaaaattg taaggatatt attttgaaat ggaatcaggt tgtaaaaaaa
    22981 atagataacc ttattgaaaa tggaaaatat attcaagaag atgtatatac agagcaagaa
    23041 agcataaaaa ctgaggaaga atattttgat gaagatacct atacggaaca aaactctaaa
    23101 gaaaatgaac aagattggca aagagaacag gaaattttgc tgattcaaga tgaaagagaa
    23161 gtatcttatg aagaggcgga ggaaatatat gaaaggcaag cagaaataga acataatgcc
    23221 tttgcaaccg gtgtagagaa taacatatcg tcaactcaaa gtaacaagga ttattggatt
    23281 gtagaattta atgaaggctc aaatctgata gaaaaaaatt atgccggaga agttgttacg
    23341 aaaaaattgc ttgatgaaat caaggtgctt gacgaaaaaa ttagagttca taataagact
    23401 gtcggtgaag atgaatacgg agaaatgaca gatgaatggg taggttattc taaattctat
    23461 tttgaccata ttgtagacgg gaaagtagaa gaacacttca gaatggatat cggggatgga
    23521 aatgaggtaa accaaagaga ttttcaatat ctttatgagc agattgaacc ggaaaaagaa
    23581 aataaagaat acgggatgga tagtatagat agtgtcataa aagatatttt agaaaaagaa
    23641 tctatgactg tggtatcaag caaagatgat tatataaagt tatttccata ttttagaaac
    23701 tttgtatata ccgatggtct aaggcttgat gaatataatc cgtttgaaga tgatgaaaat
    23761 atttcggatt taattcgact gacttttttc caaaataatg atggagaata tagggtagtc
    23821 tataacaatg cggacagttt actgtattca agcaatgttg actatttttt ggagaaaata
    23881 gaggctgaaa aggtaaggtt agaagataat atagctgaga taccgaatga agataaaatt
    23941 gccgttaagg ttgggaatta ctatgctgtt gtagaaaaag aaagagtaaa ggatatatcc
    24001 ttagaagaaa caggagttcg tgtttatccg aaagaaaata actttgaggg aaaaatttac
    24061 ccattgtatc gtggcagcac ctttgaagaa agtgcaaaaa tagataaact tttcgatgag
    24121 attgcaatag gcatgaaaga ggtcaatttg accgatttaa atgatgtttt ttatcttgaa
    24181 aatcaaggac tttatgaaat ttcatcggat agggtaacgg aagaaaaagc cggatacgat
    24241 tttgaagtgg caagttttaa tgaacagttt cctgattact ataatgacat ttatgtatat
    24301 aacagaaatt taaaaataga tggtgctaat caaaacattg catatatcaa tagagaaaat
    24361 gaaatacatt ttaatgtaaa tctaccggaa gaagaaaaag caaaggtgct tgaaattaga
    24421 gataagaaag aagtcttatc aactcttatt tttaaagatg taaaggaggt cggcgaatat
    24481 cagtttcatc cacaaagcga agaatttatc ttaaatgaat tgagtatatc tgaagaaaaa
    24541 ttaaaagcac cggaacatat aacagataag attgataaga aagaaggcta tgaggctgaa
    24601 cttgttttgg atatgaaaaa caaggagtta aggcagcatt taagatataa cggatatatg
    24661 ttaagtagca atgtggcggt ttcctatgat agttataaag caatacttaa aaatctttct
    24721 tatctgcttg atgataatca tagaaatatt atgcttaccg gctatgtcaa cgaacagatt
    24781 gaaaaggata aagcaaagga agaaagaaaa gaacctgtat atcaagaggg aatgaatgta
    24841 aggtatcaag gcaaagaata tatcatttca gaaattcaag actataaaac atataaaaca
    24901 ataaagctag atgattcaga aggatattta aacggcttta taacgggcag tgaaattatt
    24961 ccttttagaa atgaaagaga acttgatttg gaaatcatat ctacaacaga gaagttacaa
    25021 gaacaaagta taaatggtga agatcttatt ctgttagata ttgaagaata taacaaaaaa
    25081 ggactttccg ttatctttca aaataaagag tatgaaatta caggaaataa ttttaatcct
    25141 gtaggaatga gcaggttaca acttgtctcg aatacagaaa aactgatgac agaaatttca
    25201 tatacacctc aaagaccggt cgcaaatctt tatgcaaaaa aagatctcct tgaaaggttt
    25261 aatttaaatg agaaaaatag tgaaaaaagt attgaagcaa agcaaatgtc tttaacagat
    25321 atatttgagg aacaggatac aacaaaggga aaagaagaaa tttcaagtga gaaagaacgt
    25381 gtacctgtca atataggggc aaaggtaatc tatcagggag aagaatatac agtaagtgcc
    25441 tttgagtata ataatatttt agagaaaaat gatatatggc taaatcctgt atcaaaaaat
    25501 aatcatcaaa ttccgattgt aagtttttct gacagagaag agctaaatga aaagctcatt
    25561 gttatagata ccaatcttaa cttaggagaa gacaagtcgg aactgttaca tcatagttta
    25621 gatgtaataa atgataaagg ttctgtgatt gccaatcagt ttattgtaaa agtcgataat
    25681 caaaacaggg aacttacagt atatagtgaa caaaatccta atagtcatag agaatttgaa
    25741 ctttcttttg attatctaaa cgggcttggg caaattgacg gagatggaaa taatctaaaa
    25801 cttacaaagc ataaaaaaga aaccattgat aaaaaattga aaagttatca ttcttggaaa
    25861 gaagatgggg aaaaaagagg aattccggga atagcaggtt cttctattac ttcacctatt
    25921 actgatgaaa tgttttggca gatgaaagaa tatgaagaaa aattaaaaga ggaggaaaga
    25981 tacgcccctg atgataagta tttgggaggt attcctccaa tcaattacaa aatcacaaaa
    26041 gaagatgaaa tcttgccgcc gtccgaaagg cttaaaaata acatagaagc catcaaggta
    26101 ttaaaagaaa ttgaggaaag acatagtcat gcaacaaagg aagaacagga tattttgagt
    26161 agatatgtcg gctggggtgg actttctgat gtctttgatg aagaaaaggg aggacaatgg
    26221 aaagatgcaa gagaattctt aaaagaaaat ctatcaccgt ctgagtacga tgcagcaagg
    26281 gaaagtaccc ttacagcctt ttatacaccg aagattgtaa tagacagtat ctatcaagcc
    26341 gtattaaata tgggatttga aagtgggaat atcttggaac caagtatggg aactggcaga
    26401 tttataggca atcttccaga cagcatgaaa ggcagtaaat tttatggtgt agaacttgac
    26461 agtataagtg gtaggatagc aagtaggcta tatcctaatg ctaaaataca gatcaaaggt
    26521 tttgaagaaa cgactttttc aaataatctg tttgatgtag cggtgggaaa tgtaccgttt
    26581 ggagaatata agatagttga tcgtgagtat gagaaaaaca attttcttat tcacgatttt
    26641 ttctttgcca aaaccttgga taaagtacgt tccggtggag tagtagcctt tataagttca
    26701 agtggaacta tggataaaaa gagtgaagat atcagaagat atatttcaga aagagcagag
    26761 tttttaggag caattagact acctaataat acttttaaag gcgaggcggg tacggaagta
    26821 acaagtgata ttatttttct taaaaagaga gatcgactgg taaaacttga tgaagaatgg
    26881 gtaaaacttg gcactgacga aagaggactg acatataaca aatactttgt agataaccct
    26941 gatatggtac ttggaaatat ggaagaaata tcaagcagat ttggaacaag tcttgcctgt
    27001 gttgcagatg aaaatagtac tctgaaagaa cagctggata ccgccattaa aaacattaaa
    27061 ggaagttatg agaagataga attaaataat gaatttgaag tggaaaccat tccggctgat
    27121 gacagtgtga aaaattattc ttatgcagta attgatgata aggtatattt tagagaaaat
    27181 tccgttatgc aaaaattgaa tttaaataaa aatgatgagg aaaaagtaag ggcatatctt
    27241 ggaatagaaa aagcattaag acaggtaatt gcttatcaaa aagaagatta ttccgatacg
    27301 gaaattaagg agaagcaagg ggagttaaat cgtatttatg atgagttttc caagaaatac
    27361 ggaattttaa acagtaaggc gaataaaaaa ctgtttcgtg aagacgctaa ttattcttta
    27421 ctgtccactt tggaaaagct ggataaagaa ggaaacttta tagaaaaatc cgatatcttt
    27481 acaaaaagaa caataaaaaa agcagtagcc atagagcata ccgacaatct gacagaagca
    27541 cttatcctat ctatttctca aaaagggaaa gtcaatttcg agtatatgga aaagctcact
    27601 gaaaaaacaa gaggagaaat cattgaagga ttaaagggag aaatattctt aaatttagat
    27661 ggatttgatc caagtgatac gactcctttt tcttcagcca tagacttggg agatttttca
    27721 agatcttacg taactgctga tgaatattta tctggaaata tcagagataa aatagaagta
    27781 atagattcgt atataaagaa tgtagaacat gaatttgaac aaaatgaaca gcttgaaaat
    27841 attgatgcag atgtactgaa acagggtagt gagactttaa aaaaagaact gtccagttta
    27901 aattaccaaa gacaaaagct gctagaagta atgccaaagg agcttgaggc aagtgaaata
    27961 accgttagaa tgggagcaac ttggatacct gagaaagatt ataagagctt tatgttccat
    28021 cttctaaaaa catcggcatc taatagatgg aatattgata ttaaatatac caattttaca
    28081 ggggagtaca gagttgaagg taaaagtata gataaaggaa acgaccttgc caatttcaca
    28141 tacggaacaa gcagagtaag tgcatataaa ctgattgaag atacattaaa ccttagagat
    28201 accaatgtat atgatcaagt cattgatgaa aacggaaaga aaagttctgt actaaatcaa
    28261 aaagaaacga tgcttgcaag aagtaaacag gaaattatca aagaagagtt taaaaattgg
    28321 attttcgatg atatagacag aagaacaagg cttgtaaaag aatacaatga gaaattcaat
    28381 tcgataaggc ttagagaata tgatggaagt aatttaactt ttgacggaat gaatcctgaa
    28441 atagagctta gacctcatca aagagatgcg attgctagag gacttttcgg tggaaacacc
    28501 ctacttgcac atgaagttgg agctggaaag acttttgaga tgataggaat tgctatggag
    28561 tctaaaaggc ttggaatgag taacaagtca atgtttgtag ttccaaacca tattgtagaa
    28621 cagtttggta gagagtttaa tgaactgtat ccggcagcaa atattctttg tgcaacagaa
    28681 aaagacttta caccagataa aagaaaaaga ttttgctcaa ggattgcaac cggtgattat
    28741 gatgcggtaa ttatagggca ttcgcagttt gaaaagattc caatttcaaa gcagcgacag
    28801 gagtatgaac ttcaaagtca gattgatgaa attatagatt ttatcgaaga atataaaagg
    28861 aatagagatc agaaattcac cgttaagcag cttgaaaaaa cgaaaaaagg actggaggca
    28921 aaactaaaga aattaaatga tgattataga aaagatgatg tcgtaacctt tgaagaattg
    28981 gggatagaca agctatttgt agacgaagtt catgctttta aaaatttgta cgtttttaca
    29041 aaaatgcgta atgtagcagg aattacaacc acagattctc aaaaatcaag tgatatgctg
    29101 atgaagtgca gatatatgga tgaaattacc ggtaataagg gtattgtatt tgcgacagga
    29161 acccctgtga gcaattctat ggcagagctt tataccatgc agcgttatct ccaatatgac
    29221 gaacttaaaa aaatgcactt gcaacacttt gattcttggg catctacttt tggagaaact
    29281 gttacagcaa ttgaacttaa tcctgaaggg aacggatatc gaagcaagac aagatttgca
    29341 aaattttata accttccgga actgatgaat atggtcaagc agtttatgga tataaagact
    29401 gctgatgtat taaatcttcc cgttccaaat gctcattatg aaacgataaa aaccaaaccg
    29461 acagaagaac aaaaacaaat ccttgaaact ttttctgaga gagctgataa ggttagagga
    29521 aaacaggtgg attcctctgt cgataatatg cttctgatta ctaatgacgg aaagaaaatg
    29581 gcacttgacc aaaggttaat taatccatta cttcctgatg atccgaacag taaagtaaat
    29641 acctgtgtaa ataatatatt cagtatttgg gataaatata gggatgagaa gtccacacaa
    29701 ttagtttttt gtgatatgtc aacaccatca agtgaattta atatttatga tgatataaag
    29761 gagaagctga caaaaatggg gattcctaaa aatgaaacag agtttattca taacgcaaag
    29821 aacaacaaag aaaaagataa gattttcgat aaggtacgaa agggtgaaat tcgtgtgctt
    29881 ctcggttcaa cgcagaaaat gggagcaggg acaaatgctc aaaataaatt gattgctacc
    29941 catgatctcg atgtaccctg gaggcctgcg gatttggagc agagaaaagg aagaattgta
    30001 aggcaaggta atgaaaatga tgatgttcat atctttcgtt atattacgga aaataccttt
    30061 gatgcgtatc ttttccaaac acttgaaacc aagcaaactt atatatctca aataatgaat
    30121 tcaaagacac ctgtaagagt agcggaggat attgatgaag ctacattaaa ttatgcggag
    30181 attaaagcac ttgcaacagg aaatccgctt attcgtgaaa aaatggacct tgatgttgag
    30241 gtaagtaaac ttaaaatgct ggagtccaat tttaaatcca acctatataa aatggaagat
    30301 aaggttgtaa aagtatatcc aaaagaaatt aaaagtctaa aagaaaaaat agaaaatttg
    30361 aaaaaggata tagaaaaagt ggaaccgtat agggaggaaa aactagaaaa atatgatcag
    30421 actactttag aaaatatggg tgaaaatgaa aaacaagtgg ggataaaagc agataaagaa
    30481 gcaatatcaa aattcacatc tttaacttta aatgggaaaa aatataccga taaaaagcaa
    30541 gccggagagt tcttaataaa caagataaaa ggaataaaaa aattagatga ttttcgttct
    30601 gaggaagtaa aaatcggaga atatagaaat ttcgatttgt tcgcatatta tgacaggttc
    30661 tccaatcagt ataaattcaa tctgaaggga gaagaaaatc attatgggga gtttggaacg
    30721 gatgaaatcg gaaatatcac ccgaatggat aatgtacttg ataggatgcc tgagagattg
    30781 gagcagacac ttggaaaact taaagatacc gagaatcaac ttgaaacggc gaagcttgaa
    30841 ataaaaaaga aatttccaca ggcagagctt ttaaaagaaa agacgttaag acttgctgag
    30901 gtaaataatt tgcttgatat gggacaaaaa ggagatttaa aagaggagaa aaatccactt
    30961 ttggaagaag tgaaggaaga actgattcat tttctaaata aagaatatga tgaagcacac
    31021 agtatagaag atttcgatac aatgtttcct gacttgacag atataggttt ggcatatacg
    31081 actacaccgg atgaaaagca tgagatacag acaagtcttg atttaatcaa ttacaagatg
    31141 aacacttatg tagacaatac tttaattgac agttttcagt atacttacga tccacttaat
    31201 gcaagtgata cgaaggaact tatacaaatc aaaacgaaca taggtttttg ggattttaat
    31261 gagctggtat atgtggatga agaaaagtta aaagcatcac ttggacttga aattgatgac
    31321 gatggtaatt tctatgatcc gctttcaaag gatatggatt tagatggagt aatggacagg
    31381 tatgatgcag actttagaga tagtaaagta caaagttttg gagatttgga taaaaaagaa
    31441 aaagcatccg taatggatag gcttggatac ttcaaagaaa agataaagaa aggaggccta
    31501 caaaatgaaa atattgatag aaagatagag tgtaaggagg aggttagata gttggaatat
    31561 cacaaaaata ttagagcaac ggatagagaa atgcagaaac tttttgaaaa tgaggagtat
    31621 aactattccg taagatattt tgaaaaaata gaagaaaact tatttaaaac gataattcgc
    31681 acaccggaga atatagagtt tccaaaatcc aaaaccttgt ctataaacac gataaaaaaa
    31741 ctcttagaaa cagatgtaaa tattaactct atgtatatca gagatgaatt cactaaaatg
    31801 aaaaataagg tatacgaatt taatcaaaaa aaatatccgg gttatgagga tatggatata
    31861 aaactaacaa tatctactat taagggtatc gaggatttcg atacccttaa tgatttttat
    31921 gatagtttga aaaggaaggg atatttagaa gcgataaaag aaagtattaa aaatattatt
    31981 gataaagaat tagaagaaaa catacaagta aaagtacagg aggtaaaaaa tatgaaatta
    32041 gaaaaaggcg atattgtaaa aacagcatta agtgaaaaca caacagtttt ggatgtgaaa
    32101 gataatcagg cggtactgtt ttcaggtact cagtttgtac ttgcaacagg gattaaagaa
    32161 aacaaggaaa gcggaaaatt tgaatgggat aatgggcgat atgcaaatga tttaaaaagc
    32221 atttccgata tacaaaacaa taattttgaa acgatgaaag agaccttatc ttttttagca
    32281 gagtataatc atagcgattt tgtcaaagga attctgtctc ttgaaacagg aatagaaaat
    32341 gaggatactc ttgatgctgc ttatgataat tatatgaatg ataaaattat gggtttggtt
    32401 gatgaaaaat tttatcatta tatagatgaa aatgagattg aagcacctga tttagaaagc
    32461 gaaatacagg ataagaatag tgttttatcc gatgaggaaa atgtaaagga ggacaataat
    32521 actacgagtg agaagtcaaa tgaaaataag gaaaaagcaa atactgtaaa tatcaatggc
    32581 aatattgctt cagatataga cattaaaaat ttgacatcga aagatggtag agattttact
    32641 gttgcaagtt ttgcagttgc tgaaaatgac aaggagggaa atgtaaaata taccaactgt
    32701 ttagcctata acgataaggt aagtagtgta gaaaatttga aaaaaggaga ttttgttcat
    32761 gtattcggaa aagaaaaaat cagtcaggga aaggacggaa aggaatatac atctcttaaa
    32821 gtttattctg caaagctgtt aaaagccaaa gaacagagca aaacaaatca aaatgcaaag
    32881 gatgtaaaga aaccgtcagc acttggcaag ttaaaagagt ataaggaaaa ggcaggcgaa
    32941 aaatcaaagg aacaggtcag tgtcaaaaaa gataaaaata tagagagata aaattataaa
    33001 aatagtgggt aaatagctga tagggctgtt tatccactat ttttctttgt ttttttatta
    33061 gaaatg
//
LOCUS       DARYJX010000025        31750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYJX010000025 DARYJX010000000
VERSION     DARYJX010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1435)
                     /locus_tag="TU257_001164"
     CDS             complement(<1..1435)
                     /locus_tag="TU257_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0834181.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU257_001165"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU257_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL0834182.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU257_001166"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU257_001166"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL0834183.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU257_001167"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU257_001167"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL0834184.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TU257_001168"
     CDS             complement(5344..6630)
                     /locus_tag="TU257_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL0834185.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TU257_001169"
     CDS             complement(6772..7143)
                     /locus_tag="TU257_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL0834186.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TU257_001170"
     CDS             complement(7130..7402)
                     /locus_tag="TU257_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL0834187.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TU257_001171"
     CDS             complement(7433..8944)
                     /locus_tag="TU257_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL0834188.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU257_001172"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU257_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL0834189.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TU257_001173"
     CDS             complement(12410..12979)
                     /locus_tag="TU257_001173"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0834190.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU257_001174"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU257_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL0834191.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TU257_001175"
     CDS             complement(14337..14702)
                     /locus_tag="TU257_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834192.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TU257_001176"
     CDS             complement(14823..15020)
                     /locus_tag="TU257_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL0834193.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU257_001177"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU257_001177"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL0834194.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU257_001178"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU257_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL0834195.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TU257_001179"
     CDS             complement(17976..18749)
                     /locus_tag="TU257_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL0834196.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TU257_001180"
     CDS             complement(18869..20092)
                     /locus_tag="TU257_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL0834197.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TU257_001181"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TU257_001181"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL0834198.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TU257_001182"
     tRNA            complement(21081..21154)
                     /locus_tag="TU257_001182"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TU257_001183"
     tRNA            21435..21506
                     /locus_tag="TU257_001183"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TU257_001184"
     tRNA            21539..21612
                     /locus_tag="TU257_001184"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TU257_001185"
     CDS             complement(21873..24458)
                     /locus_tag="TU257_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL0834199.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TU257_001186"
     CDS             complement(24581..26200)
                     /locus_tag="TU257_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0834200.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TU257_001187"
     CDS             complement(26280..27152)
                     /locus_tag="TU257_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0834201.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TU257_001188"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TU257_001188"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL0834202.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TU257_001189"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TU257_001189"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL0834203.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TU257_001190"
     CDS             30654..31046
                     /locus_tag="TU257_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0834204.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TU257_001191"
     CDS             31121..31522
                     /locus_tag="TU257_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0834205.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31750
                     /locus_tag="TU257_001192"
     CDS             31519..>31750
                     /locus_tag="TU257_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0834206.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDS"
BASE COUNT         9884 a         6363 c         5841 g         9662 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa
//
LOCUS       DARYJX010000026        31390 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYJX010000026 DARYJX010000000
VERSION     DARYJX010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31390
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..174
                     /locus_tag="TU257_001193"
     CDS             <1..174
                     /locus_tag="TU257_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834207.1"
                     /translation="EAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIA
                     AGTIAIPKRKEED"
     gene            complement(420..734)
                     /gene="trxA"
                     /locus_tag="TU257_001194"
     CDS             complement(420..734)
                     /gene="trxA"
                     /locus_tag="TU257_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL0834208.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            914..2233
                     /locus_tag="TU257_001195"
     CDS             914..2233
                     /locus_tag="TU257_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL0834209.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2573..4909)
                     /locus_tag="TU257_001196"
     CDS             complement(2573..4909)
                     /locus_tag="TU257_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL0834210.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IEIAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(4982..5527)
                     /locus_tag="TU257_001197"
     CDS             complement(4982..5527)
                     /locus_tag="TU257_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL0834211.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5527..5838)
                     /locus_tag="TU257_001198"
     CDS             complement(5527..5838)
                     /locus_tag="TU257_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834212.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            5956..6864
                     /locus_tag="TU257_001199"
     CDS             5956..6864
                     /locus_tag="TU257_001199"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL0834213.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6889..7488
                     /gene="lepB"
                     /locus_tag="TU257_001200"
     CDS             6889..7488
                     /gene="lepB"
                     /locus_tag="TU257_001200"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0834214.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7717..10116
                     /locus_tag="TU257_001201"
     CDS             7717..10116
                     /locus_tag="TU257_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL0834215.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10212..10697
                     /locus_tag="TU257_001202"
     CDS             10212..10697
                     /locus_tag="TU257_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834216.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TU257_001203"
     CDS             complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TU257_001203"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL0834217.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12152..14476
                     /gene="pflB"
                     /locus_tag="TU257_001204"
     CDS             12152..14476
                     /gene="pflB"
                     /locus_tag="TU257_001204"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL0834218.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14780..15058
                     /locus_tag="TU257_001205"
     CDS             14780..15058
                     /locus_tag="TU257_001205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834219.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15222..16163)
                     /locus_tag="TU257_001206"
     CDS             complement(15222..16163)
                     /locus_tag="TU257_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL0834220.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16160..16915)
                     /locus_tag="TU257_001207"
     CDS             complement(16160..16915)
                     /locus_tag="TU257_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL0834221.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17408..18256)
                     /locus_tag="TU257_001208"
     CDS             complement(17408..18256)
                     /locus_tag="TU257_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL0834222.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKGSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18358..18810)
                     /locus_tag="TU257_001209"
     CDS             complement(18358..18810)
                     /locus_tag="TU257_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0834223.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18830..20029)
                     /locus_tag="TU257_001210"
     CDS             complement(18830..20029)
                     /locus_tag="TU257_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0834224.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20198..20857
                     /locus_tag="TU257_001211"
     CDS             20198..20857
                     /locus_tag="TU257_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0834225.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20878..23163
                     /locus_tag="TU257_001212"
     CDS             20878..23163
                     /locus_tag="TU257_001212"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL0834226.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23269..23661)
                     /locus_tag="TU257_001213"
     CDS             complement(23269..23661)
                     /locus_tag="TU257_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL0834227.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23815..24072)
                     /locus_tag="TU257_001214"
     CDS             complement(23815..24072)
                     /locus_tag="TU257_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834228.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24251..24625
                     /locus_tag="TU257_001215"
                     /pseudo
     CDS             24251..24625
                     /locus_tag="TU257_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24883..25665)
                     /locus_tag="TU257_001216"
                     /pseudo
     CDS             complement(24883..25665)
                     /locus_tag="TU257_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26182..27690)
                     /locus_tag="TU257_001217"
     CDS             complement(26182..27690)
                     /locus_tag="TU257_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0834229.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            27941..28837
                     /locus_tag="TU257_001218"
     CDS             27941..28837
                     /locus_tag="TU257_001218"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0834230.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28885..29097
                     /locus_tag="TU257_001219"
     CDS             28885..29097
                     /locus_tag="TU257_001219"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL0834231.1"
                     /translation="MQSLEGGNSPIVEQNYGSTEGYHGQSGILEETEDTNPPGIILGG
                     SGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29024..29830
                     /locus_tag="TU257_001220"
     CDS             29024..29830
                     /locus_tag="TU257_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0834232.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30202..31248)
                     /locus_tag="TU257_001221"
     CDS             complement(30202..31248)
                     /locus_tag="TU257_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0834233.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31250..>31390)
                     /locus_tag="TU257_001222"
     CDS             complement(31250..>31390)
                     /locus_tag="TU257_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL0834234.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9381 a         7384 c         6253 g         8372 t
ORIGIN      
        1 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
       61 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      121 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      181 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      241 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      301 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      361 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      421 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      481 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      541 tgagcagtat tgggattgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      601 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      661 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      721 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      781 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      841 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      901 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
      961 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1021 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1081 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1141 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1201 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1261 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1321 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1381 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1441 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1501 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1561 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1621 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1681 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1741 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1801 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgggc agctaacagg
     1861 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1921 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     1981 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2041 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2101 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2161 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2221 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2281 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2341 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2401 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2461 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2521 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2581 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2641 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2701 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2761 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2821 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2881 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     2941 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3001 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3061 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3121 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3181 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3241 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3301 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3361 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3421 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3481 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3541 caacataggc tatctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3601 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3661 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3721 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3781 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3841 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3901 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     3961 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4021 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4081 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4141 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4201 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4261 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4321 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4381 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4441 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4501 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4561 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4621 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4681 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4741 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4801 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4861 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4921 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     4981 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5041 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5101 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5161 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5221 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5281 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5341 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5401 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5461 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5521 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5581 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5641 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5701 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5761 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5821 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5881 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     5941 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6001 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6061 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6121 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6181 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6241 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6301 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6361 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6421 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6481 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6541 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6601 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6661 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6721 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6781 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6841 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6901 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     6961 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7021 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7081 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7141 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7201 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7261 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7321 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7381 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7441 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7501 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7561 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7621 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7681 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7741 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7801 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7861 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7921 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     7981 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8041 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8101 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8161 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8221 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8281 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8341 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8401 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8461 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8521 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8581 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8641 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8701 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8761 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8821 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8881 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     8941 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9001 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9061 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9121 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9181 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9241 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9301 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9361 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9421 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9481 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9541 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9601 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9661 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9721 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9781 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9841 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9901 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
     9961 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10021 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10081 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10141 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10201 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10261 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10321 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10381 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10441 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10501 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10561 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10621 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10681 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10741 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10801 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10861 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10921 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    10981 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11041 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11101 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11161 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11221 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11281 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11341 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11401 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11461 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11521 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11581 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11641 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11701 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11761 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11821 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11881 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    11941 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12001 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12061 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12121 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12181 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12241 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12301 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12361 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12421 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12481 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12541 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12601 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12661 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12721 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12781 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12841 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12901 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    12961 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13021 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13081 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13141 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13201 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13261 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13321 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13381 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13441 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13501 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13561 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13621 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13681 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13741 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13801 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13861 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13921 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    13981 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14041 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14101 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14161 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14221 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14281 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14341 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14401 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14461 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14521 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14581 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14641 taaaaaaaaa aacgaaacta cggagaaaag ctgatgagga gctctttaag gctatcagtc
    14701 aacatgttaa actcttctta ggaagcgtta acaataacta actgctaagc taagcaatta
    14761 tctattaagg agaataacaa tgaaacgact aaaaacacta tgcttgttag ctactgctat
    14821 aaccctaacc ctagctccta tcagcacaag ccagacaaca acacagaccg tatatgctag
    14881 tgaaactcat caaaatcttt gtacgaacac tggtaacgga tggtttaaat gtcccgatgg
    14941 acatggaggg tggacttggc attttgacga aaatcataag tcaaatcagc agtccttttt
    15001 gggaggattg ttgggctttg ctttgtctct atggggagct attattagac tcttttaagc
    15061 tctagcttaa ctaatcctca aacaacaaaa ataagctctt agagaactaa gctctaaggg
    15121 ctttttgctg ttctgataag taaaaaccaa gagacaagga catcaaaaac aagcaggcct
    15181 atcagatata ccacctgata ggcccacttg tgctctcatt cttatctagg actatttctg
    15241 tcaaaggtcc tatgaatagc atcccgaagc tgtcgtctct ctttgatcca caaggcccta
    15301 tcatccttgt cataggttct attggtgaga aaaatcgctg cctgctgctc ctttttattg
    15361 agcatgataa aaggccctgt atagcctgta tgactaatcc aatcaccctc taggctccaa
    15421 cccaaagacc tgggcttttc ctgtctgcta tagctttgaa aaagtctatc cgaaaagctt
    15481 tccttcaggt aatgctcaat aaaccgctct aaatccctga tggttgaaaa aagccctgct
    15541 gagcctgcat ggtttcccaa gaccttagcc ttgggatcat gtacctctcc atcaagcacc
    15601 cctttgaccg ttggaactgc ttctggcctt gggccaaagg aggtctcagt cattccaaag
    15661 ggagtaaaaa ccatctcctg aaaaagctca tcaagagact ttccatgaag gtgctctagc
    15721 atgaagccaa gcaataaaaa attcacatct gtgtaatgaa aggtcttatc gtccttgacc
    15781 tgaagctggt gcatcgctgc tcttaattgc tgggcattga gctgatctcg attgggaata
    15841 taagggtcaa gtccactagt atgggtgagt agctgtcgca gtgtaacctc cagcttttga
    15901 gcgtcaggat aataatgcct taaaggagta tcaagagcca aggcaccact attgatcatg
    15961 gctatacaga cagtcgctac tccgacaacc ttagagacac tggctaaatc ataaaccaag
    16021 cctttggtaa caggtctttg accatcaagg gtaccgatat aatgctcctg ccaaccgcca
    16081 cagcgaaaaa gggctaagct agccccatga tataagcctt cctgaatctg ctggcttacc
    16141 ttttctatga cttctaatgt catttgacaa accaaatttc gatctgactt gggtctgaaa
    16201 gaacaagcac ccttgccttt ttatctaaat aaacctgaca ccctttgtcc tcaaggtagg
    16261 tctttagagc aagcaagtca tagctatctg acacctgaaa ttctaaaatc tccaaatccc
    16321 atgtgacatg cgggacaatc gtcaaatctt gaccagcctc cctattaaac tcaagcgtga
    16381 ccggcaggca atcaccaaaa atagactgat aaaaagctct ggattgctcg tcatctaaaa
    16441 catttaagac aatcagatca aagctaaact gactcagccc cctaaagtca gcttccttgt
    16501 caattgcagg aacatcatcg acaatgtcaa gctccttgat atcgtcctct gcatggagta
    16561 agaagcgatc tccctctggt gaggtgactt caaaggcata gccttttttt cccttgaaaa
    16621 tcaaatcata gtcaacgcca tgagctagga gctgctcaat gtccttagga gcagttgttt
    16681 tgataacaat tgtatttact ttcttagggc catctacaac gcgtgttctt gctgctggag
    16741 attcttcaat tacaaagcgt tcttgtcctt ggccccaaga tgaaaaaatt gatatcgcgt
    16801 tttcctctga cactagcctt aagcctagat ttttttggta aaaggcaata ttaaggtcgc
    16861 gattgttaac acgtaatact ggggttttaa agacaatatt gtcaaataaa gtcatatatt
    16921 cctcctaatc ctctgctatt atagacaaaa ttccaatttt tgacaagaaa ttatatgctt
    16981 tttaaccgcc tgtcacgcgc taccaaggca atatagcact cacagccatc accagactta
    17041 ctaggtccaa tcttccttcg tgcgctctat cacaagcagc tttccttagc gtaactcatg
    17101 cacatattgg taaatgcgac tttttcaaaa tagcacatga agtacccctt taatttgact
    17161 tttccttaac caaaagcgag aacctttttt agttctcaca gtagcaatca cactcttgaa
    17221 atgtgatttc gctctcctca ataacagatg ataactgaaa ttgcccggat tttcttatcc
    17281 acgcgcaact tcaaaagcac cttatcttca gcattagtaa ggatactacc agcttagctc
    17341 agaccagatt cagctggctc ttgctggcaa gcttttatca caaaaaagaa ggcctaagcc
    17401 ttctttttta cttgatataa aggaatttga atgctgctac tgctgctact gctgctagca
    17461 ctggggcagc aaccggtacc catgagtacc accattttga atcccccttg gcttgtccaa
    17521 ggactgattt tggtaagaaa tggtgaacca aacgagggcc taagtcacgc gctgggttga
    17581 gcgctggacc agtaggacca ccaagagagg tcacaagagt catcaccaag aaaccaatcc
    17641 ccaagtgagc tactgcaagt gagcctgtca cgtaaggaga gatttgcgtt gcagctgttg
    17701 tttggtcata gccagcctct accagcttac caacaagctc cacaccaaag taattcttgg
    17761 ttaaggccat tgcgccaaaa aagaggacaa aggaaccaac aaactcgttc aaaaagccat
    17821 taatgtaggc tgccttacgg ctgcccttgt caccatcatc aactgctgaa atcgttgaga
    17881 aggatcccaa aatattgtta gggttgtctg tctgcacaaa ataaggcttg tacaccgcaa
    17941 caaccactaa ttggccaaac atagccccta gcaattgagc aagaacatat tgtaaaacgt
    18001 gtgcccaagg gaacaagcct gaaactgcca agccaaaggt aaaagctggg ttaatgtgat
    18061 ttccagaaac gttaccaaac ataagtgccg gcatcatcac accgaggcca tagccaaagg
    18121 caatcacaag ccagcctgag cggttaccct ttgttccctt taagtcaaca ttggcaactg
    18181 ctccatttcc caaaataatc aaaaatgcag tggcaataaa ctctgtgatg tatttcacag
    18241 tccatgttat ttccatattc tctagtttcc tccaaatgat aagtataaca gataccattt
    18301 tatcagggat actagttctt gtaaagccta ttgtaagata ttgcctgctt aatatgttta
    18361 cagtgttttt tcacaattac ggacaactaa taagtctttt ttagcatgtc gcaggatata
    18421 ctctgaggtc gatccaatca gcagacgctc aaaggtattt aagccagttg ctcctaccat
    18481 gatcaaatca gcctgctcct tttcaggtat gtcactagct aagagctttt tagggttgcc
    18541 tctttcgatg atttttttaa tgctgctaac gcctctgcct ctagccattt tctcgtaata
    18601 gcgcaacacc tccttggcat gctcctcttg tgtgtcaaag acataatcac taaccattgc
    18661 atcaccctga taggccttaa catcaataac atgagccagc agtaagaccg catcattgcg
    18721 aagggcaaca ttaatggcct tctcaacagc taattctgat tcgtaagagc cgtccaccgc
    18781 agccagaatc cgtttatatt tgcttatcat ctttgtctcc tttcgttgat tagcctttat
    18841 caatagcctt tgcttgtgtc tttaggaaat acatgactgc gcaggcagct ggaatgagcc
    18901 ctgccagcca gaacaattga tgaaaggact gcacaccaga cccaagaagc atatccttga
    18961 tgagtcccaa cagataaggt cccgcaccca agcccaaatc tagcccaatc atataagtag
    19021 acatagcggt attaaagcga tgctcctcaa cccccttgat ggaggctgcc tgtccgcagg
    19081 acataaaggt tccatagcca aagcctatca aagcacccga aagcagatag ggaaggctgc
    19141 ttgtcacact accaagcagg aaaagcccta gcgccaaaaa gagatagctg ggataaagaa
    19201 cccactgctc ccccttaacg tccatcaagc gtcccatagc aggtcgtgtg atcgtaatga
    19261 tcaaggcata taccacaaag aaataggctc ccaccgtcgt caaatgaatg tctgttgtgt
    19321 ataatttttg aaagcctagc acagaagcat aggcaatccc catcaaaaag gcaatcaagg
    19381 tgataaataa ggcctttcgc tcaataaagc tatcaactgt ccaggatttt gtttttgcca
    19441 gctgctctga gttgagggca atatctgtca caggaaaggc aaaggcccct agcacaacta
    19501 ctgcgatcaa cacactgcac aaaataataa tcatccgaaa atcaatgtgc aaattatcca
    19561 gcataaaggt cccaacaaaa ggaccaatcg ccgccgctag gcttgttgat agaccataaa
    19621 aattaatccc ctctccgcgc ttgctagctg gaatataggc agtcacaatg gtattggttg
    19681 ctgttgagac aacaccatag ccaaagccat taaacaagcg cacaaaatac atcatgccaa
    19741 tcgttggcat gaaaaagtag gctagcgttg ttaggagata aaaaatggcg cctcctctta
    19801 gcactaagcg tcggccaaaa acctccaatt gcttgccaaa aatcagtcga gccagcaggg
    19861 ttcctaggat ataaatcccc gtcgccagac ctgcctcact ggtcttagct cctaattcct
    19921 tagtcgcaac aaaggcaatg atcaccgtaa acaagtaata gaccatatac acaataaaat
    19981 ttaatactgt gatccctata aaatgcttgt taaataattt gtcttccact gaaaatgagc
    20041 tcctccctat ttcattaaca ttttacaaaa aaatcagata atgccccatt tcaatggtat
    20101 aatataggtg atactattaa acgacattag caaatgctaa gcattgctgc agcaacaaat
    20161 tatataatga taccagaaac acctctagga gaaaagcgtg aaccatcaaa tcttacagcg
    20221 ttatattgac agtcataact ttcctattat cgaaaagggc taccacaaat acctgacctt
    20281 tgaaagctta gaggaggatt ttacgtatat cctaaaggag ggcattgtca agcaaagcgt
    20341 tctgtcaaaa tatggcatgg aatttaacct caggtacgtc acaggccttg agatcacctc
    20401 tgtgcttaat actggctatt ccaaggacat gagagagccc tacaatgttc gcatcgaatc
    20461 tgagactgcc agcttttata aggttcgtca ttccaccttt ttaagggata ttagcgagga
    20521 tatcgagctg cagggctatg tcaaggactt ttatcactac cgcctccaaa aatcaatgaa
    20581 aaaaatgcag tgtatgctga caaatggccg tatcggcgct atctctactc agatttacga
    20641 tttaatgacc ctttttggac gccccttggc taatggccat atccttattg attttatcat
    20701 cacaaatgag gagctgggca aattctgtgg catttcgact gccagcagtg tcagtcgtct
    20761 cctaaagcag ctcaaaaaag agggcattat tcaaatcaat gaccagcata tcatcattac
    20821 caatttagag aagctaaagg ataatattgt tttttaacga tttagaaagg acgtcccatg
    20881 cgctataatc aattgtctta cattcccacc agtctagaaa cagctgtagc tgagcttcag
    20941 gccctgggct ttgctgtcca gcaagagcaa gcacccaagg agaacttcgc tattttcctt
    21001 agaaagctat tttttcattt tcaggatacc gattatccct tgagccatat gattgcaagc
    21061 aaggatctcg acctattgac ctttttaaca tctgatgcaa cactgacaaa agaggttttt
    21121 gatttagtgg ccttacaggt ccttggcttt attcctgctg ttgactttac cgatgcacag
    21181 gactttatac aaaagattgg ctttccgatt gtttttgaca gccagcaatt actactcaat
    21241 ttacatcagc tgcttgcaac ccggcagaag tccggtgtga ccttgattga tagccttgtt
    21301 agtcagggct tgcttcctat ggataattgc taccactact tcaacggaaa agccctagca
    21361 acctttgata ccaccagcct cattcgcgag gtggtctatg tcgaagcgcc acttgatacc
    21421 gatcaagacg gacagcttga cctcatcaag gtcaacatta tccgccccaa ggccagcact
    21481 gctatcccaa gcatgatgac agccagccct tatcaccaag ggattaacga gaccgccaac
    21541 gataaaaagc tccatcgcat ggaaggtgag cttagcccta aggctcctcg taggattacc
    21601 gttgagccaa ctgattttca gccgcttgcc accaagccct caaggcttcc tgtcaatgag
    21661 tgccaagaga ccttcagcca tatcagctcc tacacactaa atgattattt tctagcgcgt
    21721 ggctttgcca atctctatgt ctcaggagtg ggaacagcag gctcaactgg ctttatgaca
    21781 agtggtgact acgcccagat cgaaagcttt aaggctgtta tcgattggct aaatggcaga
    21841 gctactgctt acacgagcca caagcgtgac tatcaaatca aggctgattg gtcaaatggc
    21901 ttagtcgcaa caactggaaa atcctatctt ggtaccatgt caacaggact ggctacaaca
    21961 ggtgttgatg gcttagcagt catcattgct gaagctgcca tttcttcttg gtacgattat
    22021 tatcgtgaaa atgggctggt atgcagtcct ggtggctacc caggagagga tctcgatgtg
    22081 ctgacagagc tcacctactc gcgtaacctg ctgccaggtg attacttacg tcacaacgac
    22141 cattatcaac agctgctgag ccaacaatct caagctctcg agcgccaatc aggcaactac
    22201 aatcaatttt ggcatgaccg caactacctg ccacaggctg atcgcatcaa gtgtgaggtc
    22261 gtctacacgc atggcctaca ggactggaat gtgaagccta gacaggtcta caatatcttc
    22321 aatgccctgc ctgatagcct tggaaagcac cttttcctac atcatggtga gcatgtctac
    22381 atgcacaact ggcagtcaat tgattttcgt gaggccatga atgccctgct ctgtcaaaaa
    22441 atgctaggac aaaataatgg ctttacccta ccaacaatca tctggcagga taaccaaaaa
    22501 gaacaaacct ggaaagagct aacagccttt ggcggtcaca gcaagcgtca gattgcccta
    22561 ggcgatgatc atgtcttaat tgacaatcac tatggcgaag aggactttaa gcgctatagc
    22621 aaggattttc gtgcctttaa agctgagctt tttgaaggca aggcaaatca agcagtcatt
    22681 gatattctgt tagaagagga tctaccaatc aacgggcaag cctgccttaa gcttaagcta
    22741 aaatcaagtg aaaacaaggg gattttggct gcacagctcc tagattatgg caagaaaaaa
    22801 cgctttgctg atatacctgc tattcttgag ctagacagca ttgacaacgg gcagcagttt
    22861 gcacgtgaag cgctcaagga gcttcccttc aaggacagcc cataccgcgt tgtcaccaag
    22921 ggtgtcctaa acctacagca ccgcagcgac ctattgacca ttgaggatat tccaaatgac
    22981 caatggatga ccatcacctt ccacttgcag ccaaccatct atcatatggc caagggagac
    23041 accctaagag tcgttcttta cacgactgat tttgagcata caatccgcga caatagcaac
    23101 tatgccctaa ccctagattt ggagcaatcc tatctcctaa tccctactga tgaggaggaa
    23161 taaatcaaag cgcatcaaaa aagcctgaga tcacaatgag ctgcacccca atcgttagat
    23221 cctttgtcta actgttggag tacagctcaa agctctaggc ttttttaact attttgaaac
    23281 ctttttacca gcctcagcac cagaatgcag gctgtagacg gactcgatat gaatcaagcc
    23341 tgctgccttt ggtgcgccca tcttgccttc tgcccattcc ttggcagcct caaagacagg
    23401 accctctgta atgatttccg cacgccctac aaagcgataa ccacgcaatt gctcgcgatt
    23461 gacataagcg acctcaattt taccattagc ctgaatatta gagcaggttt ggccgccagt
    23521 attttcatta taaaccaagg tttcatcgtc taacagtctc atcgaacgct tagggccaat
    23581 attaggatta ccctcattat ctacagttac taccattgct aattgctcag caatcatttc
    23641 tttcatttct tctgttaaca tataatctcc tcttaatcgt ttctatagtc agctgactac
    23701 gctttgatta tagcacagtt aagcagaaaa gccgacaaaa ataggttagc ttaaaaaagt
    23761 tttacagttt acttaagatt agaatgattc tcgctatcta gccatcaccc ttgatcacag
    23821 taaaaaggcg attagcaagc aagcactctt tatttcataa aatccgaatc gtcgcccaaa
    23881 aaaaatatca tcaactgata tggtcaatgc ctctgcaata cctcttaatt tttcatactt
    23941 agctcgccta agcttttgca catccttttc atatctggct agtgtcctaa cagaaatccc
    24001 agttaacgct gacagttcct tttgggtctt tttttgagca atcctcaatt cctttaacgt
    24061 tgcttttgac aatattttcc ctccgcctct catctcaggt aatattaatg acagatgaca
    24121 agtttattat agacttcggt ttttatgaag tcaagtcttt tatcgcactt tccccacttc
    24181 tttttctaaa tcttttgatt tagcttgatt tgtggtatca tatcctatat agaaataaag
    24241 gagaatggaa atgtccgaaa agaaaacatt ttttgcaact aatttaaaat atcttcggct
    24301 aaaaaagaat atggaacaat tagaacttgc taacctttta ggacgaaaaa gctcttcctc
    24361 aatcagcgaa tgagaaagag gaaagtacac tccaaaatct ggtctcctga gtgacattgc
    24421 tgccatcttt gatgtcagcc tgacagacct catggaaaag gatttaacac tggaaaataa
    24481 gggagtgact tatcagcttc cccaaagaga tttagtaatg atttcagagc agctatctga
    24541 aaacaattat aacaaatggc tggattttgg tcaggatctc ttatctcatc aggataaaga
    24601 agaaaatcac aagccaagca aataaagagc ctcacacgtc ttattctcat caagtttcga
    24661 aaaatcacct accactcaag cacacaaaaa gccttggcag ggcttctaag cataagaaag
    24721 ctgtatcata tcaatacctc agggaccatg atatgataca gctttttgta tctcactttt
    24781 agacaaggta gccacataaa gcttgcagat gacctacctc tgtattagct accacaacca
    24841 acagctagct agactggcag gccctctata agcctcagcg gattatctaa gcactcccaa
    24901 cagctccaac aaaataaaga cataaccaat accattattt aagatatggg ctactgttga
    24961 aaaatagata ttcttcttcc aaacataaac taagccgagc aaaagtccca gtccaccata
    25021 cacaacgatg gaagatagct cgctgaagga atagatatga accaagccaa atagcaatga
    25081 tgatcccaac aatcgagcca gcagcatacc tgtgcctgat tggccctcac cgattaaaat
    25141 cttgcggaaa ataagctcct cattgaaggg accaataata ctcaccacca gaataaagat
    25201 cactgtctcg aagccctcac tagcattata gcgattagct aaaacagctg cattgctgct
    25261 ctcttctaaa ggaaggctac tgagcaaaat atttgcaaca taaagcactg caaaaatgac
    25321 caagacccac aaggtatttt tgacccattt tgttgaaaac tgccgccagt ccctctgata
    25381 atctgctcga taaagccaac agatcccaag tgcaaaaatc agcagatgtc tcccgtaaaa
    25441 taaaaaggta ttcaataaag gcggaagctc aatcacattg ctaacttgtc tataaagata
    25501 cacagcaatg atatatagca tgaccagtac agctgcacga tgacgtttga tggtatccaa
    25561 ttactcttcc tcaattctaa taattgtcag attagctagg ctatattgcc atcagctaat
    25621 cttgatctta aatgtgacta atttacaagc actcaacttt tgaatcggta aagctgacag
    25681 acagccctac cctagcttca ataaagctat cttccaatag tccttgcgct catcagaact
    25741 gtcaaaggcc tgacccagct gagtcaacag acttatccag tcaacatcac acagaacaag
    25801 accatcttac catatccctg ccaactataa aagcccctaa cctgacctat ttgactacta
    25861 acagcaaaaa agcagcttaa aaacaccaat cagacgccac caaggactct tgatcagcgc
    25921 agctcgcaca gacacctgaa aaatgacaga caagcctctt aaaagcacct cagcaagctg
    25981 agccaaccct tcacagaata gacaaacaac aagagctaag tcaagacctc aagctagcag
    26041 attacaggca gagacgcttg caaggcttac ccagcaaaaa gcaacagact gataaaggat
    26101 tcacaccaca cagccacaag tcaagcagct agcccaaaca aagcactgct caccaaatcc
    26161 tactatgctt tctggtagcc cttatccatt caaaatcgta tccaaggctt cttgatattg
    26221 cttgtctcgc aattctctga tcacctgtga taaatactct gcctgataca tcacaaagtc
    26281 aaaattgaaa tccagaattt tggtgttctc attcaatgac agcctctcct cgataaaagc
    26341 agtcatctca gctgttgtca caatcaagtc aaaatcagtt ctccaaggca attcagcctc
    26401 tgacaaaata ttaaaacgat agacctttgc aacacaagga ctcacctgtt gcatgaccaa
    26461 gctatataaa atatcaatgt ttttcttgtt gatttcgatc actgctatgg ctaaaggtgg
    26521 cagaccttct ctaacaagct gttccagtcg cgtgcaaagc aaatgcaaat tagagcctgt
    26581 cagccgacca acaccagaaa cccgctctgc ccagctatta atcatcagct cgatacgatt
    26641 ggccaagagc ttactgcctt gatattcctc cgcataataa tatttttgcg ggataaagag
    26701 cgacaaatca aacaaggtct tacgaaaata aggaatcaag gtctgaatac aagccttgtc
    26761 aaaggcgata tagtggccaa acaattgacg cagctcaccc agcagctctt ggtaagcagg
    26821 atcctcctga atgatcgtca ataaggccga agaatcctcc tcagaccatt gtgtgatcga
    26881 aaaagagttg ttaaccgtca aataaacgag aaaaatataa tcaatctcgc tactgggaaa
    26941 gtccatatca agcaacaatt tcccctcacg cttgaaaaag tcctccaaat acccataaag
    27001 cgccaaagac tttaagcgtt taaaaatccc ctcctgagga atcgcaacgt caaactctcc
    27061 acgcttccaa gatagcgaca agagcacatc aaaaaagcga aacttcttat ccagtaacgg
    27121 gtgaggcgtt tgttgctttt tgatcgaaaa gataaagtca tgcacaatat ccagatcatg
    27181 gtcagtcagc tcatagatga caatcccgta cttatcatgc aataaagcaa tcaaatagcg
    27241 gatacgccac tcctcaccaa caacactatt atcctctaag gccaagccgc actcctcaac
    27301 aaagggcttc atgtgctgaa tcagccgata agctgacggt gtggaaataa aatgctccct
    27361 agcaaagcct gagacagatt tgaccttata gcaaggtgcc ttgatcaaga gaaatttaag
    27421 aatgtgcagc cgtaccgatt ggcggtaaat cgtcttcaaa aacggtttgc cccttttcaa
    27481 aacggtgcag cggacaatgg tgctatccca ctcaaaggcg atatctcctt ggaaaagctc
    27541 ctctaattgg tggatatagc gctttatgtt agctaggcta aagcccgtct tttgctgaat
    27601 ggcgtggaaa ctgatccttt ttttaccaag tagtatggtc agcagcaaag cctgatgatt
    27661 aatcactggt tccaaatact cttcaagcaa aacactttct cctccttaaa ccatttcgtt
    27721 agcgtcatta tcataacaat ttttaccaaa aaagtgatga aaaatattta atatcaggac
    27781 gatttttctg atagccttta ttataacaca aaagctcaag gcaggtaaaa cgataaagaa
    27841 atcaacttaa aactatgaca cagtctcatc tcatatgata tagttattca ggtttcctaa
    27901 tggaaaacat attaacaact taataatgga gagaagaaag ttgaaaacaa aatcatttag
    27961 aaaggtactg acaacgtcag ctacctgtat tgtgctggca acaagctttg ccggaggaac
    28021 cctaagagtc tgggcagagc agctttatta tgggtggaat gatggaacga gacaaagttc
    28081 gccatatttt ttgtacgtat cgcctaaaaa tgctccaaag cgtgaattaa aagacgagta
    28141 tgttgtttat tgctttaaca aaaaattgta ttggccagat caatgggaat ctatatacag
    28201 caattttaat gacatcagat ctccatataa cgatttacct gtatatgaga aaaaactagg
    28261 atatgatggt atatttaaac aatatgctcc agattacaaa aaagatatta gtgatatcgc
    28321 aagtgctttg gtggcagttt taagtaatgg ataccccact aacaagtcac aactatcaac
    28381 tagctaccat ttaaataatg attcttctag aaaagttact caattagcca tttggtattt
    28441 tagtgatagt ttaacaaaag aataccttaa agatacgggt ggttataact taaacgatat
    28501 ggaaaaaaaa gctttagatt ttttaatcag taaaggagag gattctaagc ttaaatcaga
    28561 gcagagtaat tactcattgg atatttatgt ttatcaaagt ggcgggcatg accatatgaa
    28621 agattaccaa aatcttctcg gctctacctt aattcctaaa gaaccgctaa agcctcagct
    28681 aggtggtttt agtggacata atggaaatgg attaagcggc cttgaaggag gatcatcagg
    28741 ttcacaagaa actaatgaag atggtaagaa aggacttata ggtttccatg gaggactctc
    28801 aggaagcgag ggcaaacgag atcctttcca ggattgaagg gtgaggctgg tgcacctgat
    28861 acacctcaaa agcctaatga cccattgcaa agtcttgaag gtggtaactc tcctatcgta
    28921 gaacaaaact atggtagtac tgagggatat catggtcaat ctggcattct tgaggaaacc
    28981 gaagacacta acccacctgg tatcatttta ggtggctcag gaaatgtcga aacgagatcc
    29041 tcatctgatg gggcttggcg gtggtctagc tggcgaatca ggagaaacga cacctaaacc
    29101 aggacagact ggtggtcatg gaccaatcat cgagacaaca gaggacacac aaaaaggcat
    29161 gtctgggcaa tctggcggca ctatcgagtc agaaaacacc aaaaagcctg aggtcatgat
    29221 tggtgggcag ggacaaacca tcgaaacaac agaggacaca caaaaaggca tgtctgggca
    29281 atctggcggt actatcgagt cagaagacac taaaaaacct gaggtcatga ttggtgggca
    29341 gggacaaacc atcgaaacaa cagaggacac acaaaaaggc atgtctgggc aatctggcgg
    29401 tactatcgag tcagaagaca ctaaaaaacc tgaggtcatg attggcggtc agggacaaat
    29461 catcgacttc tctgaaaaca cgcaatcagg tatgtctgga cagtctggag acactacggt
    29521 cattgaggat accaagaagt ctgagataat cattggtggg caaggacaaa tcatcgactt
    29581 ctctgaggat actcagccgg gtatgtctgg gcaatctgga ggcaccacaa ttgtcgaaga
    29641 caccaagaag ccgacaccta agcctaaacc tgcacctgcg ccaattgtta atgacgaaaa
    29701 acctaacaaa ggcactcagc tcccacagac aaatgatatg aagcaactca ccctaagcat
    29761 catcggtgca atgtcaatgc tgcttgtcct atgtctgtct ctattcaagc gaccatctaa
    29821 aaaagactaa gcaacactga caagtgatca ttattgtacg gacgtttaca ggcgggcttt
    29881 ctgccctctt aaaacaccgt acaacaacaa aacggtctaa atagaaatat ccctcaaggg
    29941 ttagacaatc gctctagccc ttggggcttt ttttgatact tataatagaa gagagcaagc
    30001 agtgacactt tctttttgcc ctatatctgc taacactagc ggtatgtgca gttaccatag
    30061 gctatcaact cgtcgtgcaa ctctagagaa aagctgatac aaaaaacaag caccagcctt
    30121 gctgctgatg cttgctccgg acttactgat aagcctttgt gatgtcctag ctttataacc
    30181 atatgcctat tacctaaagg tctagtctcc taatggtggg ctggctggta aaagcaagga
    30241 gaaacagctc ccctttccaa gctggctctc aacagcaata tccccaccta gttggcgagc
    30301 taactgccta gcaatagaga gccccagccc atgaccacca gtcttcatat tgcgagaggc
    30361 ctcaacacga tacaggcgct tgaaaatcaa aggcaggtcc tcttttttga tcccttgccc
    30421 ctgatcaata acatcaatgc gaatggactg ctcctgttga taagcatgaa tcgtcaaagc
    30481 cgtattagcc tttgaatatt taagcgcatt gctgactaaa ttcagcataa tccgagacaa
    30541 agcatcatat cggctgctga tcttaaccac ctcttttgcc acctcaatat gaacggagcg
    30601 tttttcctgc tctaaggtca attgaaattc ggatagcatg tcaatcaata gcttttcaag
    30661 atagatgatt tgaagctgct gcttgtcgtc ttgcttttga tcatttaagc tgaccatatg
    30721 caattcttca actaattgat tcaaacggtt ggtctgtcgt gagatggtgt ttagatagtg
    30781 cctttcctct tcccttggaa taacgccatc taaaatcccc tctacagttg cttgaataga
    30841 ggtcaagggt gtcttaatat cgtgcgacag ctgagcaatc atcatggatt tctcatgctc
    30901 actctcactc aatgactcaa agctgacctt tagctctgag gacatctgat taaaggcttc
    30961 ctctagatct ttaaactcca aaggacactt gatgagctga ccactatcaa agtttctttc
    31021 agaaatagcc tgtatctttt tctttagcct tttaagcgat gaaaaaacat tactcaaaag
    31081 gatcatattc acaattcctc cggctactga agcaattaga gctattacta aaatatatga
    31141 aatatcctca atggtaatga gcatttggtt taacccaaca atcaggcctg caatagtaat
    31201 cagcatagac attaaatagc caatgacaat gtacgttctt aatcgcatgc tacccctcta
    31261 atttataacc tagtccccaa accgttttaa tggttggtgt ttgctcggta ctgtattttg
    31321 ccaagtcatt gcgtagggaa tgaatgtgaa catttaaggt attggtatca tctaaatact
    31381 cctcctccca
//
LOCUS       DARYJX010000027        31131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYJX010000027 DARYJX010000000
VERSION     DARYJX010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU257_001223"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU257_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL0834235.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TU257_001224"
     CDS             complement(1584..2021)
                     /locus_tag="TU257_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL0834236.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TU257_001225"
     CDS             complement(2008..3234)
                     /locus_tag="TU257_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0834237.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU257_001226"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU257_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL0834238.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU257_001227"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU257_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL0834239.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TU257_001228"
     CDS             complement(5505..6662)
                     /locus_tag="TU257_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL0834240.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU257_001229"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU257_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL0834241.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TU257_001230"
     CDS             complement(7553..8392)
                     /locus_tag="TU257_001230"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL0834242.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TU257_001231"
     CDS             8708..10276
                     /locus_tag="TU257_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0834243.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TU257_001232"
     CDS             10269..11009
                     /locus_tag="TU257_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0834244.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TU257_001233"
     CDS             11357..11473
                     /locus_tag="TU257_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL0834245.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TU257_001234"
     CDS             complement(11997..12887)
                     /locus_tag="TU257_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL0834246.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TU257_001235"
     CDS             complement(13150..14814)
                     /locus_tag="TU257_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL0834247.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TU257_001236"
     CDS             complement(14814..15179)
                     /locus_tag="TU257_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0834248.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TU257_001237"
     CDS             complement(15331..15519)
                     /locus_tag="TU257_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL0834249.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TU257_001238"
     CDS             complement(15979..16344)
                     /locus_tag="TU257_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834250.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TU257_001239"
     CDS             complement(16934..17815)
                     /locus_tag="TU257_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL0834251.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TU257_001240"
     tRNA            complement(18018..18103)
                     /locus_tag="TU257_001240"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TU257_001241"
     CDS             complement(18158..19084)
                     /locus_tag="TU257_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0834252.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TU257_001242"
     CDS             complement(19444..21057)
                     /locus_tag="TU257_001242"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL0834253.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TU257_001243"
     CDS             complement(21331..21897)
                     /locus_tag="TU257_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL0834254.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TU257_001244"
     CDS             complement(22164..23447)
                     /locus_tag="TU257_001244"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL0834255.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TU257_001245"
     CDS             complement(23796..25205)
                     /locus_tag="TU257_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0834256.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TU257_001246"
     CDS             25656..26495
                     /locus_tag="TU257_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL0834257.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TU257_001247"
     CDS             complement(26591..27151)
                     /locus_tag="TU257_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL0834258.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TU257_001248"
     CDS             complement(27164..27637)
                     /locus_tag="TU257_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0834259.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TU257_001249"
     CDS             complement(27643..28392)
                     /locus_tag="TU257_001249"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL0834260.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU257_001250"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU257_001250"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL0834261.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TU257_001251"
     CDS             29318..30682
                     /locus_tag="TU257_001251"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL0834262.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         9264 a         7451 c         5668 g         8748 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat actgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggcgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa g
//
LOCUS       DARYJX010000028        30363 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYJX010000028 DARYJX010000000
VERSION     DARYJX010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30363
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(109..792)
                     /locus_tag="TU257_001252"
     CDS             complement(109..792)
                     /locus_tag="TU257_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEL0834263.1"
                     /translation="MLLDVVIQFRDRRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            850..1038
                     /locus_tag="TU257_001253"
     CDS             850..1038
                     /locus_tag="TU257_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834264.1"
                     /translation="MEETASVNVTVKINNITEFSTLVEKFNEKARELEAISHELMRFK
                     FQGEIESRALSDNANEIE"
     gene            complement(1012..1479)
                     /locus_tag="TU257_001254"
     CDS             complement(1012..1479)
                     /locus_tag="TU257_001254"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834265.1"
                     /translation="MDLNQVRLLEACHRYLVDRVHIDIKENMLNDKLVFEFNGDFVTF
                     NTYQEVGHCCFYEYELGSYEELENHRSIDVTEILSILNLKSGQIGTLSMLTDITRVRA
                     YIFKLLSQADFAKFEKEIKNTNFAYNFRYVENYSYLPCVKIDKDKLFNFVSII"
     gene            1553..1741
                     /locus_tag="TU257_001255"
     CDS             1553..1741
                     /locus_tag="TU257_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834266.1"
                     /translation="MQILLYKLRKEKRISQEEMSKVINKSSNTYRDKELGKRDFTQSE
                     MFKIANFFHKELGEIFTP"
     gene            1792..2508
                     /locus_tag="TU257_001256"
     CDS             1792..2508
                     /locus_tag="TU257_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL0834267.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            complement(2663..2878)
                     /locus_tag="TU257_001257"
     CDS             complement(2663..2878)
                     /locus_tag="TU257_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834268.1"
                     /translation="MVDKYIPGRYIQREIDEIIELVRDRSKFEPVRVREVQEHIQKIL
                     IQHEAEILARLEENQDQKASENSNDIF"
     gene            3067..3357
                     /locus_tag="TU257_001258"
     CDS             3067..3357
                     /locus_tag="TU257_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834269.1"
                     /translation="MAIEVFGPDFRKELLADLISLNREALKIAQFENSKSIEWVTMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGA"
     gene            3359..3553
                     /locus_tag="TU257_001259"
     CDS             3359..3553
                     /locus_tag="TU257_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834270.1"
                     /translation="MNKLELFLLAATVILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKRWSEKRSRGEVEKCLL"
     gene            3688..3867
                     /locus_tag="TU257_001260"
     CDS             3688..3867
                     /locus_tag="TU257_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834271.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            4040..4312
                     /locus_tag="TU257_001261"
     CDS             4040..4312
                     /locus_tag="TU257_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834272.1"
                     /translation="MDNSKLANHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(4302..4682)
                     /locus_tag="TU257_001262"
     CDS             complement(4302..4682)
                     /locus_tag="TU257_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834273.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            4738..5181
                     /locus_tag="TU257_001263"
     CDS             4738..5181
                     /locus_tag="TU257_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834274.1"
                     /translation="MAKTYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYKELKEWFVSSYDKRLEGLVLEDD"
     gene            5298..6110
                     /locus_tag="TU257_001264"
     CDS             5298..6110
                     /locus_tag="TU257_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL0834275.1"
                     /translation="MGKEKTKIYFWLKFDKKFFENIFIKRLKKMAGGDTMTVLYIRLM
                     LESLETDCILYYEGYFENLVEELAIKLEVSEDDINMTLAYFTKCGLIQIDGSGNAQMP
                     QAKAMLESETNWAKYKRETRKIGQIPTNVQPMSNQCPTEIEIEKDKKKDINIDIKSEV
                     EEEIKEISTADENSLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKSAITRA
                     ADNSKRSFGYVNSILRNWRQNGITTMVKVKEESRNFKARKAKQEEVSEYDTW"
     gene            6097..6879
                     /locus_tag="TU257_001265"
     CDS             6097..6879
                     /locus_tag="TU257_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0834276.1"
                     /translation="MTLGDNNALAKIAVAYQKNVKKESTVCQKHGCIYITILKTGLTV
                     CPMCHKEDLESQNELHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRVITPKQ
                     QEVLSWAKSMANYWYTGGKGNIIMTGKAGRGKSHLAYSIIRGLSDETKKLGLLVNITD
                     LLSEIKRDFSQEAFWLDKLKNVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPVEIRKNYGERIASRIRKGCAKSHIMDFAGLEDERIKLWN"
     gene            7016..7222
                     /locus_tag="TU257_001266"
     CDS             7016..7222
                     /locus_tag="TU257_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834277.1"
                     /translation="MTPEEAEKAKIRAKQEIEVFSIYLEQAIDTFGSMLSPQEVFLAA
                     GFAYLGAGQTDIHAAVEGLYEQVR"
     gene            7384..8310
                     /locus_tag="TU257_001267"
     CDS             7384..8310
                     /locus_tag="TU257_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL0834278.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SKSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISIPKDITPPETNSLDDLIGHQNEKKDAPGNLKDVTDDLHSEPEKTLTDENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            8307..8507
                     /locus_tag="TU257_001268"
     CDS             8307..8507
                     /locus_tag="TU257_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834279.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREECVFYDTPIDEVIKRLLDD"
     gene            8500..9297
                     /locus_tag="TU257_001269"
     CDS             8500..9297
                     /locus_tag="TU257_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL0834280.1"
                     /translation="MTSLDLLGKDYYSKESAIRYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFEGEEAHEEFKVQNSSEMISTRGTTKGQLKKDYLVAEQMI
                     DALKSDNNFMAIYQGEKEVAITGFLGEVEFKGKIDCLNAERGYFVDIKTTKGPIDDKI
                     WNGQERVYWFEAYSYILQMAAYKNMLEAKHKKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            9476..9817
                     /locus_tag="TU257_001270"
     CDS             9476..9817
                     /locus_tag="TU257_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834281.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            9814..10326
                     /locus_tag="TU257_001271"
     CDS             9814..10326
                     /locus_tag="TU257_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834282.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASQLRAIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            10313..10525
                     /locus_tag="TU257_001272"
     CDS             10313..10525
                     /locus_tag="TU257_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834283.1"
                     /translation="MTTTKKHVVRIYNKGITATYAVTDKRLFREHEFATKREAMQFIR
                     ELELANDKRATEYYLREWRDANGRYV"
     gene            10503..10787
                     /locus_tag="TU257_001273"
     CDS             10503..10787
                     /locus_tag="TU257_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL0834284.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            10812..11024
                     /locus_tag="TU257_001274"
     CDS             10812..11024
                     /locus_tag="TU257_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834285.1"
                     /translation="MSFRLSWEINGQTVEVIGDYKTLKAAYDSIKVHVKDRDKFASPY
                     YRIWQKGAVHFVDYGKHNAFYKIEER"
     gene            11029..11229
                     /locus_tag="TU257_001275"
     CDS             11029..11229
                     /locus_tag="TU257_001275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834286.1"
                     /translation="MMDTETLEAVYDALQLSLPKIIDMLKAASATRDDAYKEGVLDGA
                     DLIADTVIKAIGQMIDPEADHG"
     gene            11222..11449
                     /locus_tag="TU257_001276"
     CDS             11222..11449
                     /locus_tag="TU257_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834287.1"
                     /translation="MAKDDFLTGFVLTLLAACVFAAGFVIGSDCSSEHYEQQMTDLRM
                     QLVSTQQQLKQSREQNQRQTKRIAELTGNGG"
     gene            11460..12149
                     /locus_tag="TU257_001277"
     CDS             11460..12149
                     /locus_tag="TU257_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0834288.1"
                     /translation="MEIKCGNCLQLLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVAGLEKTQH
                     PTQKPVALMRDIITRHTTKGAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAK
                     KRIAELTGNGG"
     gene            12153..12335
                     /locus_tag="TU257_001278"
     CDS             12153..12335
                     /locus_tag="TU257_001278"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834289.1"
                     /translation="MPELINTADLQTPIEALENNLDFFKSFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            12325..12483
                     /locus_tag="TU257_001279"
     CDS             12325..12483
                     /locus_tag="TU257_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834290.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            12502..13083
                     /locus_tag="TU257_001280"
     CDS             12502..13083
                     /locus_tag="TU257_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0834291.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADWIEGHKADYITWEKADKADFVFRCINDLFNFGADMHTYDFDVSYEISKW
                     TQEHAYGFIVAVLFGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFSEIIDT
                     DFYSREDVRLTESEIRKDFDWAWERGFAKGVKE"
     gene            13080..13247
                     /locus_tag="TU257_001281"
     CDS             13080..13247
                     /locus_tag="TU257_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834292.1"
                     /translation="MNKSEIKNLVDRLSDLIDKCENDFEAMVFNPDGTFDLLLASHSA
                     LSKVLRGEVTE"
     gene            13244..13459
                     /locus_tag="TU257_001282"
     CDS             13244..13459
                     /locus_tag="TU257_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834293.1"
                     /translation="MKSYQKRFVEEYRQLTQRLSKLDKMLKKYAQGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            13533..13970
                     /locus_tag="TU257_001283"
     CDS             13533..13970
                     /locus_tag="TU257_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL0834294.1"
                     /translation="MGNIPTPKANNFLEELKTIPDLIETLERDANLMSRSLIKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            complement(14475..14852)
                     /locus_tag="TU257_001284"
     CDS             complement(14475..14852)
                     /locus_tag="TU257_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL0834295.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(14904..15089)
                     /locus_tag="TU257_001285"
     CDS             complement(14904..15089)
                     /locus_tag="TU257_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL0834296.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            15205..15540
                     /locus_tag="TU257_001286"
     CDS             15205..15540
                     /locus_tag="TU257_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL0834297.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            15703..16170
                     /locus_tag="TU257_001287"
     CDS             15703..16170
                     /locus_tag="TU257_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL0834298.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            16185..17939
                     /locus_tag="TU257_001288"
     CDS             16185..17939
                     /locus_tag="TU257_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL0834299.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKMVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            17936..18106
                     /locus_tag="TU257_001289"
     CDS             17936..18106
                     /locus_tag="TU257_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834300.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            18099..18365
                     /locus_tag="TU257_001290"
     CDS             18099..18365
                     /locus_tag="TU257_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834301.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEVLRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            18399..19619
                     /locus_tag="TU257_001291"
     CDS             18399..19619
                     /locus_tag="TU257_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0834302.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAYISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            19597..20262
                     /locus_tag="TU257_001292"
     CDS             19597..20262
                     /locus_tag="TU257_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL0834303.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            20287..21474
                     /locus_tag="TU257_001293"
     CDS             20287..21474
                     /locus_tag="TU257_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL0834304.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASVEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEGLRFEGKDEVLIPLNQTTPVDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKESGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQTLDTLKDKNGRYLLQDSITSASGKVFLGKPVFVLSDDVIGED
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            21619..21921
                     /locus_tag="TU257_001294"
     CDS             21619..21921
                     /locus_tag="TU257_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0834305.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            21918..22265
                     /locus_tag="TU257_001295"
     CDS             21918..22265
                     /locus_tag="TU257_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL0834306.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            22262..22639
                     /locus_tag="TU257_001296"
     CDS             22262..22639
                     /locus_tag="TU257_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0834307.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            22636..23106
                     /locus_tag="TU257_001297"
     CDS             22636..23106
                     /locus_tag="TU257_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834308.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFYLKERGKNGKSKIWTT"
     gene            23078..23668
                     /locus_tag="TU257_001298"
     CDS             23078..23668
                     /locus_tag="TU257_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834309.1"
                     /translation="MGKVKFGLRDFQYAVLGEDDNVATKKGGIKKLPGMKSAKLDITN
                     ELVTVSADDGPYVVLSGGITETKLEIEVLDLTTDARKDFFGIKVAAGVEKYNKNLTPN
                     NVACIFRTSDENGKAIWVGLLKGKFNLPGMETQTKEGSPNPKADTVTGNFVSRGTDGD
                     VLVIGREESHEFNYEAFAGFVFAGATDIKKGENFEM"
     gene            23720..24046
                     /locus_tag="TU257_001299"
     CDS             23720..24046
                     /locus_tag="TU257_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834310.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            24094..24243
                     /locus_tag="TU257_001300"
     CDS             24094..24243
                     /locus_tag="TU257_001300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834311.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            24256..28179
                     /locus_tag="TU257_001301"
     CDS             24256..28179
                     /locus_tag="TU257_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL0834312.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRALATETSVFTRFGKAAEKIGGKMKSLGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGIKTGDILSFSRTMIDLGESTNLSAEEAASSIAKIANITGLTSKEY
                     SRFGSSVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQTLSAIETAVINGGEDLTKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIIGSTIQGIGKMSQGLGALSGWLRTFKTGA
                     AAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGTAVSATEANALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMITAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGISYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWENMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNASDKTAGETQSAQNKIDNVKQRVPADVKAS
                     DKTGPDVASADRAVNSPKQKSPAVIRAQDNASGVAEGVIGALARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAMVNDQKGPLYKELVTLPTGESFIPSGRNVILPLPRGSKVLK
                     ASRTKQLFPHYASGIGFDDTKIASLTTRLKSVQDKGQVIINTDPQLAELIKLLKDRDD
                     RNVTNNYTVNATNSSSSEDMFSQENMRRLLRELAYYTNGEGGRLA"
     gene            28179..28886
                     /locus_tag="TU257_001302"
     CDS             28179..28886
                     /locus_tag="TU257_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL0834313.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDIDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKGTGN
                     GVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTEHHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            28883..>30363
                     /locus_tag="TU257_001303"
     CDS             28883..>30363
                     /locus_tag="TU257_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834314.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGAFAHLFKEEMKIKSDAGRRTKWQTFEINRVLRNSKEHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKTPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEHEKPEEQLVTLPEFIIDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQQQIDKRNQR"
BASE COUNT        10551 a         5037 c         6609 g         8166 t
ORIGIN      
        1 tggaaggagg aacgatatga acgaactaga aagaacagcc cttaatgaaa tcatgaggac
       61 agtgacttat atagcggaga agctggataa aattgattct aagatttctc agtctgtaga
      121 agtgaacgat agtgcatcgt cagcgtcgta gtctgccgca acaaattgag cagctgctaa
      181 aataaaacgt ttgagatcct gcaagtcttt attattatgt ctacgaacat aatgagtttc
      241 atcgttacca atccacgcca ccgagcgaga tagagcttgg agtttaggga agtcggagag
      301 atagtcacta attacttttc caagcataat ttgtttgatg ttgtcgctgt cgtcaggatt
      361 ctttgatatt gtataatctt tgattaaaaa ctcagcagct ttacggtaac caacacctgc
      421 aatttgatcg agtttttctt gctctgcaat tgtagcttgg gagtatatct ctacaaatgc
      481 tggcgacact ttatcaacgt tttcaggaag attcactcta ataggtggac gatagaagta
      541 ggcgacagct gatcctttac caatctgatc gtggatatac tctacagcaa aatattttaa
      601 gcaatcatcg aaagagcaac ggaatatcac tgaaaaatgc ccctgatatg aataactttc
      661 attgtcagaa cttttgcttt cgccaacgtg ttgaggggac atagttcgac cacagtgggg
      721 gcaagtcgaa ggtgtatcaa tcgtgattgt acttctacga tctctaaatt gtataactac
      781 atcaagcaac attattattt ctctccaatc gttttattta aattatacca cagaaagggg
      841 gtggggaaga tggaagaaac agcctcagta aacgtaactg taaaaattaa taacataact
      901 gagttttcaa ctttagttga aaagttcaac gaaaaagccc gtgagttaga agcgatttct
      961 cacgagctaa tgcgtttcaa atttcaaggc gagattgaaa gtcgtgcgct atcagataat
     1021 gctaacgaaa ttgaataatt tatctttatc aattttaacg cacggtaagt aactataatt
     1081 ttcgacatat cgaaaattat aggcaaaatt agtatttttg atttcttttt caaattttgc
     1141 aaaatccgct tgggatagaa gtttgaaaat ataagctctt actcttgtta tgtcggtaag
     1201 cattgagagt gtaccaattt gccctgattt taagtttaag atgctcaaga tctcagtaac
     1261 atcaatactt ctgtggtttt ctagctcttc atatgagccg agttcatact cataaaagca
     1321 gcaatgccca acttcttgat atgtattgaa agtcacaaag tctccgttga attcaaaaac
     1381 tagtttgtca ttaagcatat tttctttgat gtcaatatgt actctatcaa caagatatct
     1441 atgacaagct tccaataatc gaacttgatt taaatccatc acattcacct cctttctgcc
     1501 catattatag cagattagag gtactaaaaa cagatagaaa ggaggtgggg gaatgcagat
     1561 tcttctgtat aaactgcgaa aagaaaaaag aatttcacaa gaagagatgt ctaaggttat
     1621 taataagtct tctaacactt accgagataa agaattaggt aaaagagact tcacacagag
     1681 tgaaatgttt aaaatcgcca atttctttca caaagaatta ggcgaaattt ttacaccata
     1741 aacttcacga aacgtgaaat ataaatcaac acaacactag aaaggaacaa catgaatcaa
     1801 ctaataaaca tcaccctaaa cgaaaatcaa gaaccagttg tcagtggtcg tgatttacat
     1861 aaagtacttg aaatcaaaac agcttataaa gattggtttc caagaatggc tgaatatggt
     1921 tttgaagaag gtcaggactt tagctcattt ttgagcaaaa gtacaggagg tcgtcctagt
     1981 caagaccacg ttctaaaact agacatggca aaagagattg ctatgttaca gcggaatgaa
     2041 aaatctaagc aagtccgcaa gtattttatt caaatcgaaa aagactttaa cagccccgag
     2101 aaaattatgg caagggcgtt gctgatggcg gacaagaaag tgcataaatt agaagctcag
     2161 attgaggctg accgacccaa agtactattt gctgatgccg taagtgctag caaatcatct
     2221 tgtctgattg gtgagttagc taaaatcctg aaacagaatg gaatcaatat tggtcagaat
     2281 aagctatttc agtggcttag aacgaacggt tatctaatta gcagacgcgg cgagtcatgg
     2341 aatcagccaa cgcaaaaaag tatgcagctt ggattgtttg aactcaaaaa aacagccatc
     2401 aatcactctg acggtcacac tacaacaaat gtaaccccaa aagttactgg taaggggcag
     2461 cagtatttta tcaacaaatt tcttaaccag gaatatctgc cagtttagaa aggaaaccac
     2521 atgagaccaa aacgatatcc gtatacacca aaaagaccct ttccgagtca agaaagagtc
     2581 gcaagttata gattggctat tgaagagtta aattctttag caccaacagc atccgaaaca
     2641 ctaaagaaaa aaatagaaga agctaaaaaa tatcatttga gttttctgaa gccttttgat
     2701 cttgattttc ttctaaacga gcaagaatct cagcttcatg ttgaataaga attttttgaa
     2761 tatgttcctg gacttcacga actctaactg gttcgaactt acttctatca cgaaccaatt
     2821 caataatttc gtcgatttct ctttgaatat aacgaccagg aatatattta tcaaccatgt
     2881 aatttatcct cctttatagc atatttgact aacgacttca taaggaatag atggtttgtc
     2941 ataaatcaat tatagcagaa agagggggca tagaagaatt tatatacaac aaaaaagtcc
     3001 gacgggaatc ggactcaaaa caaaaactat ttacttagat tataacacaa gagagaggaa
     3061 ggttccatgg caattgaggt atttggacca gatttcagaa aggaactact tgcagacttg
     3121 atttctctaa acagagaagc gctaaaaatt gctcaattcg agaactctaa gtcaattgag
     3181 tgggttacca tgaagcggtt ggaaaaagaa actggatggg ggcgaactaa attgacccag
     3241 tggagagaac aagggaaatt taactttaaa aggtcatcag aaaacgggaa agtactatat
     3301 gacctagcag atgttaatag atttttgcga acaagtggat atgaaaaagg agcataacat
     3361 gaacaaacta gaattatttt tattagcagc aaccgtcatc ttagcaatca ttgcaagaat
     3421 tcagtatgaa gtcataaaaa aacataattc gcccgaaaat aagcgaaaaa tttttaggga
     3481 agtagcttta gaaaacagca aaagatggag cgagaagcgc tctagaggag aggtagaaaa
     3541 atgccttttg taaaacggta gaaaccacat agtcctttga caactgaata gggtaccttg
     3601 aaaaaatatt aaaaaagttt gattttgggg ttgacttatg tatccacata atgatattat
     3661 atatttgtgg atacgaaagg aggaaatatg accactacca aaaaacttgg tcgtccaact
     3721 tctaatccta agtctcatag caaaagactg agaatgacag acgaagaagt acaaaaatta
     3781 gaatattgta ctaaacaaac tggaaaaact cagacagatg ttttgatgct aggcttagat
     3841 aaggtctatc aagagctaaa aaaatagcgt ataatccgcc atcgccaaac tttggattac
     3901 acgctatcga ccgacctgaa aacaggtaca caaatatatt atcatgtgta cccttttcag
     3961 tcaacctgac aagggtattt tttgcgccct tgttgtttag ataagggttt ttattgtacc
     4021 caaaaatagg aggaacacaa tggataattc aaaactagca aatcatcaaa aagtaacggt
     4081 agtctgtaca gattttaatg tctatttgaa tggaatacga cttactggag ctagaccaga
     4141 aaccgctaaa ttagctgaga gatgcggaga gaaactcatt acactaagtc tagtagttac
     4201 agattttgat gaccatagaa cacctaagat ggcggatatg gcaaaggagg ctgagatggc
     4261 taataaaaca ttggactggg agaaaaagca tttctataaa tctaataaat aatgtatctc
     4321 agagcgttat agattgattc tggattttgc gaaactccaa attcattaag ccattcgata
     4381 acctcggttt ctacctgccc gatatatcca agaaaataca tgccttttgg tgtcagaccg
     4441 tcaattgtat atattcgtct atctaatctc ggcatttctg tggcagtaac taaatcttgt
     4501 tggatcaaac aatctagggt gtaaaaaata atttcttcaa cttctcgata agggtattga
     4561 gaatatatcc tttttccttc ttctgttgca ataaggtatt gaagtaaatc tacacccgta
     4621 tccaacttat gatatccgat ggcttcaagt gaatttttgt ataaagaata gtaatcaatc
     4681 atacacttct ccaagtattt tattttaaat ataacaaaat agtaagagga aaacaatatg
     4741 gctaaaactt acacattaac cgaagaagaa ttgaatgaat tagtagctga gcgcatgaaa
     4801 caagcgaaag aaaaacgcac accacaagga ctattcaaag atgtcagctt tgatgatgag
     4861 ttgattccaa tcaatgaaaa atatccaaaa gtactcaaga aattaaatcg tgaacgtgct
     4921 tataaaccag aaaaacacgt cttcaatcag acaccaaaag tttttggtgt ggacaacgat
     4981 attagttata gcaaaattac aacacatgac gtacacaacc atattcgttt gcttgtccta
     5041 aatgtctttg gtaaaagtca aaataaggaa gtattgcccg aggaatatga ccaagcaata
     5101 gagctttaca aggaattgaa agaatggttt gtgtctagct atgataagcg attagaggga
     5161 ttggtgctag aagatgatta aaaaattctg cgttaactac ttactaagac agattaacaa
     5221 aagcaaacta gaaacaagag ataaagcgaa gttaaaccac tttatcacac tagtggacta
     5281 caagttagga ggataaattg ggtaaagaaa aaactaaaat atacttttgg ctaaagttcg
     5341 acaagaagtt ttttgaaaat atttttatca aacgtttaaa aaagatggct ggcggagaca
     5401 ctatgacagt cttgtatatt cgtttgatgc tagaaagttt agaaacagac tgcattttat
     5461 attacgaagg atactttgaa aatttggtag aagagcttgc catcaagtta gaggtgtctg
     5521 aagacgatat caatatgaca ttagcttact tcacaaaatg tggtctaatc cagatagacg
     5581 gtagcggtaa cgcacaaatg ccccaagcta aagctatgct ggaaagtgag acgaactggg
     5641 caaaatataa acgagaaact agaaaaattg gacaaattcc aaccaatgtc caaccaatgt
     5701 ccaaccaatg tccaacagag atagagatag agaaagataa aaagaaagat ataaatatag
     5761 atataaagtc agaagtagaa gaagagataa aagagatttc tactgctgac gaaaacagtc
     5821 tcaaaattat atctgattat ttccaacaag aaatcggtat tttgtctcca aatcagtttg
     5881 agcagctgtc agactatatt accattacaa aaatggaggt agatgttgtt aagtctgcta
     5941 ttacaagagc tgctgacaat tctaaacgtt cttttggtta tgttaactct atactgcgca
     6001 attggcgaca aaatggaatc accacaatgg taaaagtgaa agaagaaagt aggaatttta
     6061 aagccagaaa agctaagcaa gaagaggtct cagaatatga cacttggtga caacaacgca
     6121 cttgctaaaa tcgctgtagc ttatcaaaaa aatgtcaaaa aagaaagcac tgtttgtcaa
     6181 aaacatggtt gcatctatat cacaatcctt aaaactggat tgacagtatg tccgatgtgt
     6241 cacaaagagg acttagaaag ccaaaatgag ttacacgtcc aaaagcaata tgagagagag
     6301 cttgaaaaca agcgactgta ctatctcaaa aaattatcaa ttatggacga cgagttggaa
     6361 aatgcctcat ttgataattt cagggtgatc acacctaagc agcaagaggt cctttcgtgg
     6421 gcaaaatcca tggctaatta ctggtataca ggaggcaaag gcaatatcat catgactggt
     6481 aaagctggcc gcgggaaaag ccatctagca tacagcatca tcagaggttt gtctgacgag
     6541 actaaaaagt tagggctgct tgtaaacatt actgacttgc tatcagagat aaagcgagac
     6601 tttagccaag aggcattttg gctagataag ctaaaaaatg ttgattattt ggttttagat
     6661 gacttaggcg ccgaaaaggt cagcgactgg tccacaagta ttatttacag cttactaaat
     6721 aagcgtacaa atacaatcat tactacaaac ttaacacctg ttgaaataag gaaaaattat
     6781 ggagaacgta tcgcatcaag aattagaaaa ggctgcgcta agagccatat tatggatttt
     6841 gcaggactgg aagatgagag gatcaagcta tggaactaat attaataact ttttttggcc
     6901 tatctgaaga acatgcagcc aaaatcatgg cgctagacga agatagccga ataaataaaa
     6961 tcgaggaatt gagagcatgg agagaatgct caaaaataac attttaggag gaaatatgac
     7021 accagaagaa gcagaaaaag caaaaatcag agctaaacaa gaaattgaag tttttagcat
     7081 ataccttgaa caggcgattg atacttttgg cagcatgcta agcccacaag aagtcttctt
     7141 ggcagcaggg tttgcctacc ttggcgctgg tcaaacagac atacatgcgg ccgtcgaggg
     7201 gttgtatgag caagttcgat gactttaaat ttagcgaaga ctgggagagt aactactttg
     7261 aggtccaagc tttgctagga caagagatag acaagctaca aaatagagtt gtccagttag
     7321 caaacgaaaa taatagatta aaggccgaaa attggcagtt aagacacaga aagaggaaat
     7381 gaaatggcga atcaattatc aacatacaca cacaaacaat tttttaatgc accaacaatt
     7441 caaaaggctt ttgatgacgt ttggaaaggc gccgggacac agttcgcagt aagcatcttg
     7501 tcagtactac aaggtagtaa aagtttgaaa tcggcatcta atgaatctat ttatgcagca
     7561 gctatgaaag cagccgtgtt aaatctgcct attgagccaa gcttaggaag ggcctattta
     7621 gttccgtaca aaggtcaagc acaattccaa ttaggctata aagggttgat tgagttagcg
     7681 cagcgcagcg gacaatacaa aaatattaat gcaggtatcg tctataaatc acaattaatt
     7741 tcttacaacc ctttgtttga ggaattgatc cttgacttta gtaagccaca agatgaaatt
     7801 gtagggtatt ttgccgcttt taaactttta aatggattcg agaaagtttc tttttggaca
     7861 gtagaaaaag taactgcaca tggaaagaaa ttttcaaaat cgtttgctag cggcccttgg
     7921 aaaacagact ttgatgcaat ggctcaaaaa actattttaa aagatatttt gagtaaatat
     7981 ggtccgttat cagttgagat gcagaaagct atcgatgaag acaatcaaga ttcaacaatt
     8041 tctattccga aagacattac accaccagaa acaaacagcc ttgacgacct aattggtcac
     8101 cagaacgaaa aaaaggacgc tcctggcaat ttaaaagacg taactgatga tttacattcc
     8161 gagccagaaa aaacgctcac agacgaaaat aagacggttt tagaagacac ctcttatcca
     8221 gctgatgaaa tccctgattt tgaccaagaa acaggcgaaa ttaaagctag cgaaggcaac
     8281 ctctttgata atcttggaga cttaatatga ttaaacttgt aaaaattgaa ggatattata
     8341 ttaatccaga atatgttgtt ggcgtttggg aaagatctgc tttaaatttt gacgatttag
     8401 atgaaaaagt agtggttatt caattcgttg gagataggga aagggaagag tgtgtctttt
     8461 acgatacacc tattgatgaa gtaattaaga ggttgctaga tgactagttt agacttactt
     8521 ggaaaggact attatagcaa ggaatcagct ataagatact ggtccattag tcagtacaag
     8581 cgctttagag aatgcgaggc aagggcactt gctgaattac gaggggattg gacagatacc
     8641 agagataaca ctgcgttgct cgtcgggaat tacgtccact cttactttga gggtgaggag
     8701 gctcacgaag aatttaaagt ccaaaacagt tctgaaatga tttcgaccag aggaacgaca
     8761 aaaggccaat taaaaaagga ttacttagtc gctgagcaga tgattgacgc tcttaaaagc
     8821 gataacaact tcatggcaat ctaccaagga gaaaaggaag ttgccatcac aggatttctt
     8881 ggtgaggttg agtttaaagg taagattgac tgtctgaatg ctgaacgtgg ctattttgta
     8941 gacattaaaa caacaaaagg acctattgat gacaaaattt ggaatggtca agagcgagtt
     9001 tactggtttg aggcttacag ctatattttg cagatggctg cctacaaaaa catgctagag
     9061 gcaaaacaca aaaagccgtt tgagcctatc atttacgcag taacaaagga aacaccgcca
     9121 gataccagag caatcaggat tcaaaattta gatgctatgc aaaatgagtt agacaaccta
     9181 gctcaaaaca tcaagcgttt agatgatgtt aaaaaaggca tagaaaaatc taagccttgt
     9241 ggtcattgcg agtattgcag ggcaaatcaa ttaacacaaa gggtaatgat tttttaacta
     9301 actattgcaa agtgaagctc ggcctttgca ataatcatat tttccgagcg agaaaggaaa
     9361 attgcaatat cgtcaagtta acagtattga tgatataaag agttgctaca ctcgtccttg
     9421 ccaatgctca cacacaattt tagggcgagt gtggatttta aaaaaggtga aaaatatgga
     9481 acaaattaaa attacaggaa caggaacagc actaatttta gatagagtaa accgaatctt
     9541 tgccatctct ggcggtttga ctatgcaatg ggattttatt agtgatttta aaaagattga
     9601 cgacgaaccg tcacttgatg aagatggaga actattcgaa gtagcttacg accttgtgct
     9661 tgaagctaaa cccaaaacta aaatcaatct aacatcatca tattttgcta aagagcataa
     9721 gaaagacaca gacgaaatta taaaagtatt ctcgtttatc gaagataata agagaaatat
     9781 ctttgaaacc cttggcattc gtggggtgct tgaatgagca atctagtatt atcgctagac
     9841 atctcaactt ctggtacagg ttgggcctta tttaaaggct cagaccttat ccagagtggt
     9901 gtcttaaaac ataagagcga ctcttatttc gaacgtggac gatatatggc tagccaatta
     9961 agagctatcc agtcacgagc actaaaaaaa tacgattgct cctttagcac aatcgcagtc
    10021 gaaaaaaact cggttatggg tccaaatcaa caatccatgc ttaaaatcgg cattgtaact
    10081 ggtatcatct taggacgatt gatagctgat aatgtcgtat ttatcaatgt ctcaacttgg
    10141 cgaaagcact ggaagtttag ctacaaagac cgctcaaaaa aagcaatgaa agcacagtca
    10201 aaggctaagg ctgctgaaaa ctttggcaaa atagtcaaag atgatgaggc agatgccgtc
    10261 ttgattggtg catactatgt caatcaaggc tatcttgatg gattggagac acatgactac
    10321 tactaaaaaa cacgttgtga ggatttacaa caaaggtatt acagcgactt acgcggttac
    10381 tgataaaaga ttgtttaggg agcatgagtt cgcaacaaaa agagaagcga tgcagtttat
    10441 tagagagcta gagttagcta atgataagcg agcgacagaa tattatttga gagagtggag
    10501 agatgctaat ggaagatacg tttaaaaaaa ttaaggagct tgaagctgct tgtcaggata
    10561 ggacagataa cattaaaaag ccatcacact atcaagggcg gcatggcatg gaagcaatcg
    10621 acgtggttaa aaacttcgca gcttgcccag agcacgagga gggtttttat tggggcaatg
    10681 ctgttaagta ccttttgcgg tatcacgcta aaaatggtgt tgaagacctt aaaaaagcac
    10741 gtcagaacct tgattggtta atcgagaagt tggaggaagt ggaatgatac caaaatttag
    10801 agtgtggaag aatgagtttt agattatctt gggaaattaa cggccaaacc gttgaggtta
    10861 taggtgacta taaaacacta aaagcagcct atgactcaat taaggtccac gtcaaagaca
    10921 gagataaatt tgccagccca tattatcgca tatggcaaaa aggagctgta cactttgtgg
    10981 attatggaaa acacaatgct ttttataaga ttgaggagag gtgattaaat gatggataca
    11041 gaaacactag aagcagtata tgatgctttg cagctatcct tgccaaaaat aatcgatatg
    11101 cttaaagcag catccgcgac cagagatgat gcttacaaag agggtgtact cgatggcgcg
    11161 gatttgatag ctgatactgt aataaaagct atcggacaaa tgatcgatcc ggaggctgat
    11221 catggctaaa gacgactttt taacaggttt tgtacttaca cttttagctg cttgcgtttt
    11281 tgcagcagga tttgtgattg gatctgactg tagtagcgag cactacgagc aacaaatgac
    11341 agacttgcgt atgcagcttg ttagcacgca gcagcagctt aagcaatctc gtgagcaaaa
    11401 ccagagacag actaaacgga ttgcggaatt gacaggaaat gggggataaa aaacactaca
    11461 tggaaataaa atgtggaaat tgcttacaat tactaacaga gttaactgat ggatcaatcg
    11521 atatggtgat aacagaccca ccatacaaca tatcagtaaa aaataacttt gctacaatgg
    11581 ggcggacagg tatagatttt ggtgattggg ataaaggctt cgacttgtta agttggattg
    11641 atattgcaag tcgaaaatta actaaaaatg gtggaatggt gatcttcaac gattggaaaa
    11701 atttaggaga tattgcaaga cattgcgaaa agacagggtt agtagtaaaa gatatttttc
    11761 gttgggtcaa agataaccct atgcccagaa acagagatag aaggtatatt acagacagcg
    11821 agtacgggat atgggtcgtc cgaaaaaatt ccaagtgggt atttaatcgg aaatcggaaa
    11881 aatatgatag gccggaatac agatatccaa ttgtagccgg actggaaaaa acacagcacc
    11941 ctactcaaaa gccagtagcc ctgatgaggg acatcattac gcgacacaca acaaaagggg
    12001 ctgttgtttt agaccctttt atgggtagcg ggtcaactgg agtagcttgt ctactgacgg
    12061 agagagactt tattggatat gagctaaata aagattactt taatatcgca aaaaaaagga
    12121 tagcagaatt aactgggaat gggggatgaa atatgccaga attgattaac acagccgact
    12181 tacagacacc gatagaagca ctagaaaata acctagattt ttttaaaagt ttttacaacg
    12241 acgaacgctt tgaagatatg gaaaatgcaa aaaaattgat tgagagatac gaaaaagcta
    12301 tatcaatttt aaccgaggta caaaatgaaa gttaaagatt tacataaagt gttagctaaa
    12361 gttgaccctg aacttgaagt ttggataaat gaaaaagatg gaggggttat aactaaagct
    12421 aaaaacgtga tgacttggaa tgagcatcca aataagtttt ttataaatgc agaaacacaa
    12481 taatgttaac cgaggtacaa aatgaacatc gaagaagcga taaagtattt tgaagataag
    12541 agaaaagatt atattgtatc accaagtgta atacatgtat cgactgttga ggtcataaat
    12601 attttaaaac aaattaagtt agataaacca aagccagaaa ttccgcagtt tgtcgctgat
    12661 tggatagagg gacacaaagc agattatatt acgtgggaaa aagctgataa agcagatttt
    12721 gtttttaggt gtattaatga cctctttaat ttcggtgcag atatgcatac ctatgacttt
    12781 gatgtgtctt atgagatatc aaaatggacg caagaacatg cctacggttt tattgttgct
    12841 gttttgttcg gctacacaat aaaaaaagaa aagctgtata ttgttgagat ccctaatcct
    12901 aatagtggca tagaacacaa acatattgca ctagcaaggt tagcgaatgg aaaacttgga
    12961 ttttcagaga tcatagatac tgatttttat tcaagagaag atgtccgact caccgagtca
    13021 gaaatccgca aagattttga ttgggcttgg gaacgaggtt ttgcgaaagg tgtgaaggaa
    13081 tgaataaaag cgaaatcaaa aatttagtag atagactaag tgatttaatt gataaatgcg
    13141 agaacgactt tgaggcaatg gtatttaacc cagacggaac gtttgactta ttactcgcaa
    13201 gccattctgc gttgtcaaaa gtgttaagag gagaggtaac agaatgaaat catatcaaaa
    13261 aagatttgtt gaagagtaca gacaacttac acaacgtttg tcaaagctag ataaaatgct
    13321 taaaaaatat gctcaaggca ctcttggttt tgaaccagat tgccctatca ggctattaca
    13381 ggagcagaga cgtgtgatgt cggagtatgt cgacatattg gaagcaagag caaaatttga
    13441 aggggttgat ttggagtaat aaaaaaagac gtccatgcga acgccttcat gattaaatac
    13501 ccaacaatat tatatcatga atggagagtt agatgggcaa cattccgaca ccaaaagcta
    13561 ataatttttt ggaagaatta aagactatcc ccgatcttat agagaccctt gaaagagacg
    13621 ctaacctaat gagtcggtcg ctcattaagt ctcctcaatg gtctgatatg cgagtgtctg
    13681 gtggggtcaa acaatcacag gaagacaaaa acataaaaat gttacacatg gtcagttatt
    13741 acagtgatca gattgagcgg ctaaaagacc gtcggcaaga aatggctaat ttgattgtgc
    13801 aaagcatggg aatttgtgag agccatgttt tgctaacgac ttatcttgac tgtgatggag
    13861 actacgagag agccagagaa cgcttaaaca taggtaatcg gaataaatac tttatgtttg
    13921 ttaggcgagg aaaggaaagt ctagaattga tactaaaaaa tactaattag atacaaattg
    13981 atactacata atactaataa ccatgttatt atagtactgt tgaaataaca agaagagata
    14041 accattttac caattgacta tttatttagt cgctgacttt aactacgatc aaacttgtta
    14101 ttttactaaa gcttagtagc tttgcgttaa aggtgttaaa ttactcggtt gaaccggtcg
    14161 ggtaagtcgc aaatatgaag agagttgttg agacgtaagg aaatgtcatg tgcacgcatc
    14221 ttatgatatt gcaggttcga accctgccgt ctcaatcagc gtcggggaga cgcgacccca
    14281 taccccttta aaggcagaca cgttctgatg tgtgggtttt tatgattaac cgcaagtcca
    14341 aaaccaaggg tcgcaacctt gcttgtggtt agtagggaca acggttgtaa gtcggttcga
    14401 ttccgactgt tcctgtgcta gtcatcacat cgtgatggct ttttattatg caaaaaagaa
    14461 ccactaagtg gctcttatgc ttgtagtttt aattcaagtg cctctgtgag gacttgcgag
    14521 aaattgagat tttcatcttc ggctgctttg tttaaccact cagggatagt cacgttctta
    14581 cgtacttttt tagagtggta ttttttcatg taggcaatca tatcgatgcc gattaaagca
    14641 atatcagaat cacgatactg ttcttttaag tcggaaacgg agctagcctt tggatagtca
    14701 gtatagtctt caagagcaaa gcctaagact tcgacagcca tttcgtaagc ttcttgaaag
    14761 tctttacctt gagtaattgc ttcaggtaca tctggaaatg taaccatgat atagtctgtg
    14821 tcttgtgtga atgtagctgg atagattaac ataatgattc tccttcgatc actgtgagat
    14881 aagcaaacca tctggcaagc ggattatttt aaacccgcct gctttagaat ggtatcttca
    14941 aggccttttc cgaggtcttt gttgtgtaga ggaacaatgg tttgatgtcc gttattatct
    15001 cggaattttt tgtgacttcc gttttgactg acttcataga acccattctt ttttagcagt
    15061 tttatcatct gctttggggt cattggcata ttgcttacct cactttctat acttatatta
    15121 tacacgcaat aaacatggtt gtcaataggt atgcgcaaaa aatgcgtatt tttgttttct
    15181 attttttatt atggaggtta gggtatgagg ccgcagaagt taacaattgc gggtggcaga
    15241 cgaacgactg ttgactacga tgataggtca gctgagtatc gtgactataa tcgtaacaga
    15301 tggaagtatg ataggaagac taagcagttt tataactcta agatttggag agagacaagt
    15361 aagcaagtct tattgcaaag tgattatatc tgtgcaatgt gtggtggaga agcaacgatg
    15421 actgatcaca ttgtctcagt taagaaagat tggaataaaa gattagattg gaataacttg
    15481 caagcaagtt gtaaagcttg taacgattgt aaagcaataa gagagagacg gaaaacctaa
    15541 acgtacataa aaagtaacat acgcaatcat tgttcgggaa ataccccgcc tattttttaa
    15601 cggggctata ttgttcggaa acttaagaac gcgccctttt ctgtgcaaaa aaatcccttt
    15661 ttgaaatttt tgaaactgta aagtttgtgt aaaggaggtc ttatgggaag aaatttaaag
    15721 ctagttgaaa cgacaaaaaa gcatcttacg aaagaagaaa aaatagtgcg agaaaccgcg
    15781 caaaataagg cgtctgacgg tcttaaaaag ttgcaaaaga cacctcctga acactttaat
    15841 aatgtagcta agtacgagta taggagaatc atagaagacc tccaaaacct acccctaaga
    15901 aatctcgata gagggctatt agagttatat tgcacatggt atgctatcta caaagaaaca
    15961 agtagaaaac tagatgaggt tggttatttt acgaatgatc cagacaaagg cattattcct
    16021 agtccgctta ttttaacatt ggaaaaagcc actgcgaata ttagaagtag tgccagtcaa
    16081 ttaggactaa cggtagatag tcgcatgaag atgtttattc cgaaggaaga agaaaaacct
    16141 aagagtatat ttgataaatt tggaggatag agagaaaggg ggtcatgaca atagaatacg
    16201 attattcagc aatcggcgac atctataaag atgacgcttt ttattatgca aaaatggtcg
    16261 ttgatgaaga gattaaagca agtaagaagg tctttaaagc ttgtctaaga catttgaatg
    16321 accttaaaaa aatagatgat gataatttta aatttatcta tttaccaaaa aaagcaattg
    16381 accccataat ttttattgag ctattgccag acgttaagac gggaaagcct tatcctttag
    16441 cgatgtttca gaagtttatt atcgggaatt tatacggatg gcgaaagaaa acagatcatt
    16501 ccttaagacg ctttagaaaa gctatgattt cggttgctcg taaaaatggc aaaacaattc
    16561 tgatagctgg tatcttgctt tatgaatttt tgtttgggca taatccatct atgagtagac
    16621 aattgttttg tacagctaat gaccgtacac aggctaaaat tgcttgggac atggcaaaga
    16681 agcaactctc atctttaaga gcaaaggacg ctgatgtcag aaaagccacg aaaattgttc
    16741 gtgatgagct gaaaaactta catgatgaat cttatattag ggctcttagt cgagatactg
    16801 gggcagtcga tgggttcgag ccttacgttg gcgttttaga tgagtttgcg gcatcaaaga
    16861 caaacgaaat gttagagctt ttagaatccg gtcaaggtca gcttgataat ccgtttatct
    16921 tgattatctc aacagctggt atggatttga atgtccccat gcacacaatt gagtatccgt
    16981 acatcactaa aattttagac gaagaaattg tagatgatgg ctattttgga tatgtcgcag
    17041 agcaagacaa cgaaggtgaa attaaagatg aatcaaattg gataaaatca aatccaatcc
    17101 tcgaggttga agctttgcac gataagctaa tggattacct gagaacgcgt cgtagagtgt
    17161 ctcttgaaac aggtgaaatt aacaaggtac ttatcaaaaa ctttaacatg tggcggcagt
    17221 cgagtgagga atcatatatt gataagcaat cttgggaact tgctcgtatt gataaacccg
    17281 acacacataa acgaagggtc tggctaggtg tggacgtcgg tcgtgttagt gacttatttg
    17341 ctattacacc agttattatg atggacgatt tttggtatat tgacagtttt tcttttgttg
    17401 cgacaaagta tgggttaacg gctaaagaaa agcgtgatgg tgtgtcttac agtaatttag
    17461 aacgtcaagg ctattgcgag ataacaacat tagaaagtgg ggttattgat gatgagagag
    17521 ttttagaaaa aatagaggag atggtctatt cgaatgactg ggaagttaac ggaatctgtt
    17581 ttgaccctta ccaatttgga acgctgctta cgatgattga gaaaaggcac ccagaatggc
    17641 ctctcataga ggtttcgcaa acgacaatgg ttttgaacat gccaacaaag caatttcgtg
    17701 atgatctcaa gaatggcaaa ataaagcact ctggcaatcc attgctaaca atggctgtta
    17761 ataacgctta tatcaagact gataacaatg gcatgaggat tgataagaat aagaatagca
    17821 ataagataga ccctctggac gctgctttag acgggtatgc agtttgttac ttagagccat
    17881 ttgacggctc tggttactgg acaagtgaga aaattttagg aggagagaca ctgttttgat
    17941 tggttttatt ttaaaaaaca tacatacatt aatcttgtta gctggactag gtttattgat
    18001 gtatgggttg tttttgtttg gtgataaagt tggttttatc gctagtggtc ttattttaat
    18061 ttttttagct atctatgtag atagcgtagg aggaaaacat gaataaacgc attaagaaaa
    18121 aacgtaaatt ggaaacagcg gttgtgatgc ttgttgcaga aaatgctatg caagctgaag
    18181 tactcaggaa tcaaaacaga caaattgcag agctgagatc gattatacaa caaaacgccc
    18241 aagcgacaaa tagagagttt gcagcagtta aatcagcgac gctagacaac caagcagcca
    18301 ttaagaaaat tggggatgag gtttattata tcaagcaaaa ttataagcgc aagtggcgga
    18361 aatagatgtt aatggtttag aaaggaggtg agaaatcgat gagttttttt caacctttgg
    18421 gcagttcaaa ggtgtcctat gatgactatg tatcatctgt tttagctggc gatgtctccc
    18481 aaaaatactt aggagtgtcg gctttgaaga atagcgatat tttaacagca acgtctatta
    18541 tagctgggga tattgctagg tttccgcttg ttaaaaagga tgttaatggg gacattatcc
    18601 atgatgagga tattaattat cttttaaatg ttaaatccac aaaaaatgcg agcgctagga
    18661 cctggaagtt tgctatggca gtaaatgcca ttttgactgg taattctttt tcgcgtattt
    18721 tgagagatcc aaagactaac caagctttgc aattccaatt ttacaggccg tcagaaacga
    18781 ctgttgagga gacagataac cacgagatag tttatacgtt tactgatatg ttgacagcaa
    18841 aacaggttaa atgttttgcc catgacgtta tccactggaa gttttttagt cacgatacaa
    18901 ttttgggaag gtccccgcta ctgtctttag gtgatgagat tgatttgcaa accggcggca
    18961 tcaatacctt aattaaattc ttcaaagatg gtttttctag tggcatctta aaaatgaaag
    19021 gcgcttatat aagcggtgaa gcacgtaaga gagccagagt tgaatttgaa aaaatgcgcg
    19081 agggtgcaat tggtggtagt cctttagtat tcgacgatac gcaagaatac acgccgcttg
    19141 aaatcgatac taacgtattg caattaatta caagtaacaa tttttcaacg gcgcaaatcg
    19201 caaaagcttt gcgggttccc agctacaagc ttggtgttaa tagtccaaat caatctgttg
    19261 cccagttgat ggaagattat gtcacgaatg atttgccatt ttattttgat gctatcacaa
    19321 gtgagttagg acttaagacg ctaagtgata aggataggcg tttgtatcgt atcgagtttg
    19381 atacacgaag cgtcacaggt cgcaatgttg atgagattgt caaattggtt aataaccaaa
    19441 tcttgacgcc taaccaaggc ctcgtagagc ttggtaagca aaaatcaaca gatccaaaca
    19501 tggataggta ccagtctagt ctaaactacg tctttttaga caaaaaagaa gaatatcaag
    19561 acaaggttgg tatcaaaggg aaaggaggtg aggtaaatgc caaagaggat aaatcttaaa
    19621 ggaccactaa ttgcaaataa ctctcaagaa gtttacgact attacggaat ggaagcagca
    19681 agtgctaaaa gtatcattga gcaatttcct gaagataata gcgatattgt tttggaagtt
    19741 aattcaaacg gtggacttgt gacagttggg agtgaaatct ataccgcttt acgaaattac
    19801 aaaggaaaag taactgcaga aattactggc atggctgcaa gtgcagcatc tgtggctgtt
    19861 atgggtgcgg ataaggttgt catgagtcct acagctcaaa tgatggtgca taaagcactc
    19921 tttaaatggg tgtctggtaa tagtgatgac ctagacaaag cttctaatgc cttaaaatca
    19981 agtgataaag ctattgtgag tgcctatgtc gcaaaaacag ggttatcaga agatgcaatc
    20041 atggatttaa tgcgaaatga aacgtttatg tccgctcaag atgccgtaga aaaaggtttt
    20101 gcggacgaag ttatgtcttt tgaagcagtt gctagcattg ataattccat gttgccgcaa
    20161 gctgttattg atgactatta cagaagtagg aacaaacgaa aacaagagat tagcaacatg
    20221 ttactagaaa ttgaaaaaga agaaatttta cgagggctat aagctctttt tttattggag
    20281 gaatttatgt tcgaagaaaa aatcaaagaa attaaagcga atatcgctaa tttaaaccaa
    20341 gctattgcta ctaaaacaac agaagtaaaa aatgctttgg aatcagatga ccttgaaact
    20401 gctcgctcaa ttaaagcaga aattgaagaa gctaaagcaa acctagcaga agcagaaaat
    20461 gacttgaaat tgtatgaagc tagcgttgaa aaaggcggtg cagaaaatac tggaggaaaa
    20521 gaagtgccac aagaaactaa aacatatcgc gaaagcgtta acgaatttat tcgttcaaaa
    20581 ggaacagtaa ccaacgaagg tttgcgtttt gaagggaaag acgaggttct tatcccactt
    20641 aaccaaacaa cgcctgtaga ccctaaaacg gatggtgtta agaaaacgga tgtaaaacct
    20701 gtctctagtg aagaaattct ttacacacca gcgcgtgaag tcaagacagt tgttgatttg
    20761 aaacaattca ctagcatcca cccagctaaa aaagaatcag ggaaatggcc agtattgcaa
    20821 cgtgctacag aaaaaatggt tagcgttgaa gaattggaaa aaaatccaaa actaggcaaa
    20881 ccacaattta aaaacgttga atgggaagtt aagacttatc gtggagctat cccactgtct
    20941 caagaatcta tcgatgatgc agatgtagat ttggttggta ttgttgctga aacaatcggt
    21001 caaatgaaag ttaatacaac taatgatgca attgctaaag tcctaaaaac atttgaggct
    21061 aaagctggtg tcaaaacatt agatgacatc aaaaaaatcc taaatgtaga tttagatcca
    21121 gcttacaatg tatcatttat tgtatctcaa agtttctatc aaaccctaga tactttaaaa
    21181 gacaaaaatg gtcgctactt gcttcaagac tcaatcacct ctgcgtctgg caaagtgttc
    21241 cttggaaaac cagtatttgt cctatctgat gacgtgattg gcgaagactc agcttttgtc
    21301 ggagatttta agcgaggcgt gttattcgct gatcgtaaag atttagggct tcgttgggca
    21361 gataacgaaa tttacggtca atacttgcaa gctgtccttc gctttggtgt cgctaaggta
    21421 gatgacaaag ctggatacta tgtgacattc aaaccagaac aattgccctc ataaggccac
    21481 tgaagaagtg gcgaaaccaa ctagcaaaag cactgtcgag gagattaagc gctatttaac
    21541 aagcaaggga attgacttta atgggaaaac attaaaatct gatttattaa aacttgcagg
    21601 cgttgaagag gtatagctat ggctgtatca aaagagttat tagacagtgt aaaactctat
    21661 tgtaaaattg actttgattt tgatgacgac atcatcaaag aaatgattga atctgctcaa
    21721 gaacaaatct gttttgcaat agaagacggt tctactcctg aaaagttcaa aggtcacgct
    21781 aaatttaatt tagctgtcaa aaagcaagtc aaggaagagt atgaccatcg cggtttgtct
    21841 gcggatagtt ttcgctatcc gttggcaaat ggtgttttaa acattatcca tcaattgcga
    21901 ttgagaggtg atgattcgtg attacacgca agatgaacgt caggataacg atttttagcc
    21961 aatcaggcgg gcaaaatgaa gatggtgaag tagtatctgc tgtcagaaag gacttgtata
    22021 cttgttgggc agaagtgcta aaaacgcagt tgagagattt taattatcaa tcaaagtatc
    22081 aaaacgctag caatttgcca acaaataagg atactaaggt ttttttaatt aggtataacc
    22141 ctgaattatc tatagataac acgatgtttg ttgagtttgg caagcgcatt tataagatag
    22201 ataaaatcga atctgacgaa tctggcaaag atattatcat gataagtgga gtaagcatgt
    22261 catgacaaaa ggtttagatg aaatattggc taatctgaca aagcttgaag taaaagcacc
    22321 aaaaaccgca aaagcagcag taactgaagt tgccaaagaa tttgaaaaag cacttaaagc
    22381 aaatacccct gtttatgaga ttgaaacaga tgagcggcta caggaagata ccgttatcag
    22441 tggttttaaa ggagctaatg ttggaattgt atccaaggaa atcggctatg gcaaagcgac
    22501 tggttggcgt gcgcactatc ctaacgatgg gaccatttac caacgcggac aagactttaa
    22561 ggaaaaaact atcaatcaga tgacaccaaa agctaaacaa atctacgcag caaaagttaa
    22621 ggagggacta gggctttgat tgctgaaaca gcagcttata aattattaag taacgataag
    22681 acgctaaatg agttgttgga taggctcaga ggcggtcctt ttaaaaatgg gtttaagcaa
    22741 ggcatattta cttatgatat tccagataac ccagttgact tgcgtaaggt agatttagcg
    22801 ccttttatgc gaatcaacac aacattagac ggtcctgctg attatgcaga tgatgagata
    22861 ctgtgtaacg agcaacggat caccatcaat ttttggtgca aaacagcttc tgaagctgac
    22921 caaattagca aatgtataga tgatatttta aaaaaaggcg gttttgaaag atacaccgca
    22981 aacgaaaaac caagatataa agatagcgat attgacttac tcatgaacgt aaggaaatac
    23041 cgctattttg atttttattt aaaagaaaga ggaaaaaatg ggaaaagtaa aatttggact
    23101 acgtgatttt cagtacgccg tactaggcga agatgataat gttgcaacga aaaaaggtgg
    23161 tattaaaaaa ctacctggaa tgaaatctgc aaaactcgat attaccaatg aattggttac
    23221 cgtttcggca gatgatgggc cttatgtagt gctttcggga ggaatcaccg aaacaaaact
    23281 agaaattgaa gtactcgatc ttacaaccga tgcacgtaag gactttttcg gcattaaagt
    23341 ggcggcaggt gttgaaaaat ataacaaaaa cttgacacct aataatgtag cctgcatttt
    23401 tagaacaagt gatgagaacg ggaaggctat ttgggtagga ctgcttaaag gtaaatttaa
    23461 tttacctggc atggaaactc aaacaaaaga aggatctcct aaccccaaag ctgataccgt
    23521 aacaggtaac tttgtgtctc gtggcaccga tggagacgtg cttgttattg gaagagaaga
    23581 aagtcatgaa tttaattatg aagcttttgc aggatttgtt tttgctggtg cgacagatat
    23641 taaaaaaggc gaaaacttcg aaatgtaaca atcaggttgg attttaaatc caacctttta
    23701 tttttgataa ggagtagata tgtacgaaat taccttaaaa aaaggtggtg tagataaagt
    23761 tttttcaaaa gactttatta acgttgagga taatttgttg gctgttgagc atcaagttag
    23821 acaaagcgct gtgtttagcg atgagaaaag acgcttagat tctaaagcgc atagaaaact
    23881 taacgaatct tacttgcaaa tgtttgttga tatgtacgca ggtcaattta cagtcgatga
    23941 tttaaagcaa tctgacatga gtgttttaaa tacacttaat gacctgtaca ttgcagcact
    24001 cggtggagag caagaggaag acgaaagcga aaaaaaggaa caataacccc acaagaggct
    24061 aaagaaaact tactcttgtg gatacagagc cttttgaaaa acggttatac cattttagat
    24121 attaaaaaaa tgcgcttatc tgatattgaa ttgatggtac aagcgctaga aattgaaact
    24181 gtcgaaaaag aagaagtgat tgaaacgacc ttggataagg cattcccatt ccttttcggc
    24241 tagaaaggag gctaaatggg gaatataggt gatttagtag caacggctac actagacata
    24301 tcaccattta tgtcaaacac aagaaaccta aaaacctaca tgaaaggctt agacaactcg
    24361 ttaaaagctg ttgaaaagag ttttcaaggg catggcgggc ggattaaagg tcttaaagcg
    24421 gtctatgctg aaacaggtag tgcattaaaa ggttaccaag aattactaaa aactcagtca
    24481 caaaaatata gcgacctaaa aaaagagata ggcgatgtta ataacgctac tgctgagcaa
    24541 aagcaaaaat tgattggcgc taaatcagcc atgttggaga ctgctgcgaa agtcacagaa
    24601 ttgcaaaaca gattacgagc gttagccact gaaactagcg tttttacaag atttggtaaa
    24661 gctgctgaaa aaatcggcgg caagatgaaa tcattaggtg attctgtagc aggagttggt
    24721 gctgcattta cgagaggagt taccgctcct attgtagcgg gcgctggtta tgctattaaa
    24781 gcagctgttg actatgaaac tgcgtttgcc ggtgttaaaa aaacagttga tgagacggcg
    24841 acagtatcct atgctaagtt gtcgcaaggc attaggcaaa tggctaaaga gttgccagcc
    24901 agcgcggtag aaatcgctca cgttgcagag gcggcaggtc aattagggat taaaacaggt
    24961 gatatcctta gtttttctcg tacaatgatt gatttaggag aatccactaa tctatccgca
    25021 gaagaagctg catcatctat tgcgaaaatc gcaaacatta caggactaac gtcaaaggaa
    25081 tattctagat ttggtagctc tgttgttgcc ttaggtaata actttgcgac aactgaaaga
    25141 gatattgttg cgatgacaaa ccgtatcgcc gcatctggta aacttgccgg cttaactaat
    25201 caagaaatgt tagcgttggc aactgctatg tcaagcgtcg gtatcgaggc agaagctggt
    25261 ggtactgcta tgactcaaac attatcagca attgaaactg ctgttattaa tggtggagaa
    25321 gatttaacaa aatttgctca aattgccaat atgtcatccg ctgattttgc aagagcgtgg
    25381 aaagagaagc caattgttgc attgcaagag tttattaagg ggcttggtca acttgataaa
    25441 aaaggtgaaa gtgctacaaa agtgcttgat gaactcggtt taagtggtat ccgccagtct
    25501 aacatgttga aatctttagg attagcatct gagactttag gcaaggctct tggaatctct
    25561 aacaaagctt ggcaagaaaa cactgcttta actgacgaag ctaataagcg ctatgagaca
    25621 acagagtcta agctaaaaat gcttaagaat gaagttaatg atgtagctat tgaatttggt
    25681 ggccctttgg ttgacgctct aagaaatggg ctcgaagcag gaaaaccaat tattcaaatg
    25741 gcagcagatt tagccaagca atttaactcg cttgacaaag agcaacaaca gcagattatc
    25801 aagtggggac ttattgctgc cgccgctggt ccagctttgt ctatctttgg taaaggtgtt
    25861 ggcattattg gcagtactat tcaaggcatt gggaaaatga gtcaaggttt aggagcgttg
    25921 tcaggctggt tgcgcacttt taaaactgga gcggcagcag ctagtgcagg agccgaagct
    25981 gccacagctt ctatgggcgg aatggctggc gcggttgcct tattaagcaa cccagtaacg
    26041 tggggtgttt tgctaggtgg ggcagccatt gtgggtatag gtttaattgc tgatagcatg
    26101 tataaagccc aaaaacgcac agaagagtgg ggaaccgctg tttccgcgac agaagcaaat
    26161 gcactaagta actttaagaa aaaagttgac gaaactaaca cttcgttgca aatgttcgag
    26221 gcaggcgcag gtagcgttaa gaaagtgact gaagcttttg atgatttggt cggaagtatt
    26281 gaaaagttag ctcaatcaaa attagataag aatataaact tagctaaaaa attaggatta
    26341 tcagaagaaa ccataaatgc tttgaaatcc aaaactgaat cagtggttaa caatgttaaa
    26401 agcatgaata cccagattaa agcaatcatg gagaaacaca acggtgacat gagccagttg
    26461 tcaagcgctg aaaaagaact tgttttgcga aatcaaagag aaatgattac cgctcaactt
    26521 gatttaatga agttctctgc atcagaaaag aaagctttaa cagcagcttt gaataacgaa
    26581 ttagatgccc tcaacgcaag acagttggaa aaagtatccg aaaacaccgt taagatgctt
    26641 gataaagaaa attctgctta caaaacaaaa aaagcagaat taaaagaaat tttaaagcaa
    26701 tttggaagcg atactagcaa gctaagcgct gaagaattgg ctgctagaca ggaagttttg
    26761 aatagactta ctgagttaaa tatgcagcac aacctaaaaa ccaaagcttt gaacgatcag
    26821 taccttgcta tccagaggga gcgtgtccaa cggttaaaag aatctggcaa gagtcaagaa
    26881 gaaatccacc aagggattag ccaaatggca tcagacatgg ctcagaagct tggtattagc
    26941 tatgacgatg cttaccgtaa actagcttat tatactgaga aatctggtga aacgttgaaa
    27001 gttttgtcgc gtaatacggc taatgctacg gcggaagtag cagcagctaa cgctcagtgg
    27061 gatagcttgt ttacgagcga taatccacaa caaagcctaa acgaattgtt atcgaccgca
    27121 gaaggctgga acagttttga aatcatggtt aagaatgccg acgttgaacc gacaggtaga
    27181 gccgcacttg ctgaaatgtt ggtagctggt ggccaatggg aaaacatgac gttagagcag
    27241 aagaagttgg ttgttgatgg tcaacaagcg atgattgaaa tctttgatag caaggagtta
    27301 ttagcgcagt ggcaagcatt gacgccagaa gaaaaggttt tgctagcgaa aaacttaaca
    27361 caagaaccaa ctatgtcggc tcaacaagcc cttgacagtg tcaagcaaac agtacctgct
    27421 gatgttaacg caagtgataa aacagcaggc gaaactcaat cagcacaaaa caagattgac
    27481 aatgttaaac aacgagttcc agctgatgtg aaagcatcgg ataagactgg accagatgta
    27541 gcaagtgctg acagggctgt caatagtcct aaacaaaaaa gtccagctgt tatcagagcc
    27601 caagataatg ctagcggtgt tgcagaaggt gttataggtg cattggctag aatcccaaga
    27661 agtgttacaa caaccattac aacgtttgtc cgtaagattt ttggacatga aaaagggact
    27721 gatttccacc ccggcgggtt agctatggtc aatgaccaaa aagggccgct atacaaggag
    27781 ttggtcactt taccaacggg tgaatcattt attccaagcg gacgaaatgt catcctccct
    27841 ttgccaaggg ggtctaaagt cttaaaggcc agccgtacaa aacaattatt cccgcactat
    27901 gccagcggaa taggttttga tgacaccaaa atcgctagtc tgacaactcg tcttaaatct
    27961 gtgcaagata aggggcaagt gattatcaat accgaccctc aacttgcgga gttaattaaa
    28021 ctacttaaag acagagatga cagaaatgtc acaaataact ataccgtaaa cgctactaat
    28081 agtagtagtt cagaggatat gtttagccaa gaaaatatga gacggctact cagagaatta
    28141 gcttactaca cgaacggaga aggagggagg ttagcttaat gcgatacatt gaatttaatg
    28201 gcactaaaag caatgattta ggtttattgc tagagcgcga acgatcaatt aagtcaacaa
    28261 acaacgacat tgatttaatc gaagtagcag gtcgtgacgg tgtacttatt aaagacaacg
    28321 aacgcttaaa agcggttgag caagactttc ctttttcgct ggttggtgac gtgactgtca
    28381 atcaacaaaa aataagcgaa tggttacatg tcaagggttg gcacgacttg gcgttgtctt
    28441 gggacaagga ttatatctat cgggctagtg ttgtcaatct ttttgaaata gacgagatac
    28501 ttaagcaatt tggtagatta aaagttaatt tcttaatcca ccctatcaaa tatttaaaaa
    28561 caggtaagca agaggtgcct ctcgtaaatg gaggtactct acaaaatcct ggcaatgtcc
    28621 aagctaaacc tatcttaaaa atcaaaggca caggcaatgg tgttttaacc attaatgact
    28681 ttgagacagg acttgaaaat gtacagggcg agcttgttat agatatggaa aggcatcttg
    28741 tctataagga tgttttatcg gcttgggata atatcgtaag gacagaacat catcgcatgc
    28801 ctctttttga tattggtcaa aacaaaatct catggactgg taactttact atcaccgcag
    28861 tgccaaactg gggggttaaa gtatgatacc agttttatac gaggccaaag aaaccaaatt
    28921 taggactttt ggccttggag aaattgcgga cgcttacgag gttaaagcta cacgtgagcg
    28981 taatggcaat tactcgttat atatcaaata tcctttagat ggtgcctttg ctcatctgtt
    29041 caaagaagag atgaagatta agtccgatgc tgggcgtagg actaagtggc agacgtttga
    29101 gattaatcgg gtgctgcgga atagtaaaga gcacattgag atttttgcac gccacatatc
    29161 gatgcgcaca caggacatcg ctttaaaacc atttgtgagc gggtctagca ttgacgcaga
    29221 gtcggcactg gaggtttggc gggataatct tgtcggtgat gatacctttg atgttaaaag
    29281 cgacatttta acactaggca gctttaactg ggaagttgac aagataggca atgcaagagg
    29341 cgctctcggg ggtgtcgctg gctctatctt agatgtttac ggtggtgagt acgagtttga
    29401 caatcgcaca atcatcttac ataaacaaat ggggcgtaag acccctacgg ttttggagta
    29461 tggccgcaat atcgttagcg tggaagagga gcgtttgctt gatggcaatt atacctcaat
    29521 ctatccttac gtaagatata cgccacaacc aaagccgcaa gaggaagcct ctggtaagcc
    29581 gcacatcggc gagcatgaga aacccgaaga acagctggtc actttgcctg aatttatcat
    29641 agacggtcag tatcttgact tatatgccca acgcagaata cagatggttg atttatctag
    29701 tcattttaat gatgacaaaa aagagccaac agtcgaagaa attagaaagc tggctcagaa
    29761 ataccttaaa gataataatg taggcgcacc taaaatcagt atagaggttg attatatcga
    29821 cctgtcacag acgcttgact atcaagattt tagagttatg gaggaggtcg agctttgcga
    29881 tattgtaccg ctttactatc caaagtttgg tatcacaacc gagaccgaaa aagtcgttga
    29941 gattgtctat gacgtctata cagatagcaa tcacacaata aagcttggca cgattggcca
    30001 atccatctct aagagtctga caggtggtgt tacgcagcgg attgagacgc tggaaaacaa
    30061 ccaaaaggtt attactaata atcaacagca atttgagctt aatttaccca aatacctcaa
    30121 cgatctaaac ggtaccaaga tatggtacga aaaaccagat gacaacgttg agcacaagat
    30181 aggcgatttt tggtttgaga aaaacggtaa atatcagcgt acctgggttt gggacgggaa
    30241 tcaatgggta aaaatcattg atactgagga tttaaatcct aatcagcgcg cttttgatga
    30301 ggctatggcc gagatcgaaa agcttaagca gcaccaacaa caaattgaca aacgcaatca
    30361 gcg
//
LOCUS       DARYJX010000029        30046 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYJX010000029 DARYJX010000000
VERSION     DARYJX010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30046
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..134)
                     /locus_tag="TU257_001304"
     CDS             complement(<1..134)
                     /locus_tag="TU257_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL0834315.1"
                     /translation="MKSIIEHYQARPLGEERCYAVCLPLIWQEGRWQVLYEIRSQHIS
                     "
     gene            336..662
                     /locus_tag="TU257_001305"
     CDS             336..662
                     /locus_tag="TU257_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL0834316.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            649..1074
                     /locus_tag="TU257_001306"
     CDS             649..1074
                     /locus_tag="TU257_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834317.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            1093..2148
                     /locus_tag="TU257_001307"
     CDS             1093..2148
                     /locus_tag="TU257_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL0834318.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(2252..4534)
                     /locus_tag="TU257_001308"
     CDS             complement(2252..4534)
                     /locus_tag="TU257_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL0834319.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4666..5199
                     /locus_tag="TU257_001309"
     CDS             4666..5199
                     /locus_tag="TU257_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0834320.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU257_001310"
     CDS             complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU257_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL0834321.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6541..6813)
                     /locus_tag="TU257_001311"
     CDS             complement(6541..6813)
                     /locus_tag="TU257_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL0834322.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU257_001312"
     CDS             complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU257_001312"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL0834323.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU257_001313"
     CDS             complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU257_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL0834324.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8676..10652)
                     /locus_tag="TU257_001314"
     CDS             complement(8676..10652)
                     /locus_tag="TU257_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL0834325.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU257_001315"
     CDS             complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU257_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL0834326.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12641..13105)
                     /locus_tag="TU257_001316"
     CDS             complement(12641..13105)
                     /locus_tag="TU257_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0834327.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU257_001317"
     CDS             complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU257_001317"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL0834328.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU257_001318"
     CDS             14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU257_001318"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL0834329.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU257_001319"
     CDS             15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU257_001319"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL0834330.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            16304..16939
                     /locus_tag="TU257_001320"
     CDS             16304..16939
                     /locus_tag="TU257_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL0834331.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(17000..17611)
                     /locus_tag="TU257_001321"
     CDS             complement(17000..17611)
                     /locus_tag="TU257_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL0834332.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17867..18676)
                     /locus_tag="TU257_001322"
     CDS             complement(17867..18676)
                     /locus_tag="TU257_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0834333.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18669..19511)
                     /locus_tag="TU257_001323"
     CDS             complement(18669..19511)
                     /locus_tag="TU257_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0834334.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19487..20326)
                     /locus_tag="TU257_001324"
     CDS             complement(19487..20326)
                     /locus_tag="TU257_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0834335.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU257_001325"
     CDS             complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU257_001325"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL0834336.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20884..21888)
                     /locus_tag="TU257_001326"
     CDS             complement(20884..21888)
                     /locus_tag="TU257_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0834337.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21938..23221)
                     /locus_tag="TU257_001327"
     CDS             complement(21938..23221)
                     /locus_tag="TU257_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0834338.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(23223..24467)
                     /locus_tag="TU257_001328"
     CDS             complement(23223..24467)
                     /locus_tag="TU257_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0834339.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24682..25095
                     /gene="yaaA"
                     /locus_tag="TU257_001329"
     CDS             24682..25095
                     /gene="yaaA"
                     /locus_tag="TU257_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL0834340.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            25097..26206
                     /gene="recF"
                     /locus_tag="TU257_001330"
     CDS             25097..26206
                     /gene="recF"
                     /locus_tag="TU257_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL0834341.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(26271..27134)
                     /locus_tag="TU257_001331"
     CDS             complement(26271..27134)
                     /locus_tag="TU257_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL0834342.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(27305..29734)
                     /locus_tag="TU257_001332"
     CDS             complement(27305..29734)
                     /locus_tag="TU257_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL0834343.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
BASE COUNT         9239 a         6557 c         5511 g         8739 t
ORIGIN      
        1 tgagagatat gttggcttct gatttcatat aagacctgcc atcgcccttc ctgccaaatc
       61 aaaggtaagc aaaccgcata acatcgctcc tcacccaagg gcctagcctg ataatgttca
      121 ataatgctct tcatctgtcc ttctccttat catatccatc actaagctac tttcatagta
      181 taaaatagta atcctttggt caagaaatgg ctccgattac tctctatgat atataaaatt
      241 tttatatata aaatattgac atattaaaac agaaactcta tacttaatat ataaaataat
      301 tatatataaa tacgaggcag gaagggagta accagatgta ttttccagta tctgctacct
      361 tgattgaatt tttgatttta tctattgtcg acaagcatga ttcctatggt tatgatatca
      421 gccaaaccat taagcttgtc gctaatatca gggaatcaac cctataccct attttaaaaa
      481 agctagagaa atcagactat ttaactacct atagtcagga acatcaaggt cgcaagcgta
      541 actattacac cattacagcc aaaggcgaaa agcagctgat tttcttaaag gaagaatggc
      601 aaagctacaa ggccacccta gatggcatta ttgaagggag attaaggcat gacaagagat
      661 gaatacctag cagagctaga caaataccta cgaaaattac ctaaagcaga ttattatgaa
      721 gctgctgaga actcaagtca gctagaactt aacgacggca gtatcaaaga ctcttctatc
      781 actgtagctg atacaaaaga agaaaacgac tatgactata cagacccctc cgagcttgct
      841 ataaatcatg tcacaatcaa ggagaaaaac acaattaatg gcggcgatat taatatcaat
      901 accacattag caaatccaag agatattgct tatcatgtca caacaagagg caacatcaag
      961 ctcagctctc gtttttcaaa cgccaagctt aacacagacg cagcaacagg agctacttca
     1021 tttcactctg acatagccaa tactgtcaat caaagcgacc tatcaattca ttaatcaagg
     1081 gaggatatca taatgactaa acaagatttt ctagacaagc taaagcagca gatcaaccat
     1141 ttacctcaaa aggattacca agaaatcatt gaccatttta cagagtattt tgacgaggct
     1201 ggtcctgacc atgaacaagc tattcttaaa gaactgggaa atccagagga cattgccaag
     1261 gagctattaa aagccttaga tctccccgaa aaaacagacg aagatgactg gacgaattgg
     1321 gaagttgaca acaaaacaaa gtcagaagca agctcacaaa agcttgagcc aatagttgac
     1381 attcgctata gtctgcttaa ccatgattta accattgaaa ctgctgacat tccttaccct
     1441 actatttcat acgatgataa tcgcatcaca ataagccaag atagtgacgg catgctcaat
     1501 atcattgaag actcagcagt acaaacaata cagtatggct ttcatttcct agaccgctgg
     1561 cttgcaaaat atcaacccat taccttgaca ctacctgtca accaccacct gaaaaaaatc
     1621 tctggagaaa gtgacaacaa cgatgtcacc ataaggcata tacattgtga tagcattgtc
     1681 tctaacactt acaatggaac gatttctatc agtcatttat cagatagcac tgtcaaccta
     1741 agcagcaaaa atgggaacat tattttagag cattgcaata tccagtctag taaatgtcaa
     1801 gccaaaaatg ctaacctcag ctgtgacaat agcaccctaa taaattgcca gctgaacaat
     1861 aacaatggaa acatcagatt agaagcaagt cagctaacag aaaccttcat tgaaaacaaa
     1921 aacggtaata tcatagggca gcagctgtcc ttttccaatg acatcactat catcaataag
     1981 aatggaatca ttgacatcaa ttgtcctaga gaaaacctca tctactatga cgtaaaggct
     2041 tcaaataata atggatttgt aacgattagt caagaagcag gtcgtcaaac accctttaaa
     2101 gcacagctta ccatttccaa taataatggt cttatctccg taagctaaac caaccataaa
     2161 aaaagcttct agaaagagct taaaccacaa tttctagaag cttttttatt atatctactg
     2221 tttaacgata acctgttatc tcagctatta tctaggacga ttgcttgtcc tttggacgat
     2281 aaatcagcac tcctatagcc ataaagctta acaaaaagcc aactaataca ctcgtctcta
     2341 aacctatctg ggcagttaat gatattgtct gacgaaggcc agagacaata taagacattg
     2401 gaagataagg atggagaatc tggaagatct gaccactcaa ctcaatagga taagaaccac
     2461 ccgcagcacc aacctgtagc aacagcataa ttaacgaagc aaaggcacca tatcgagcat
     2521 cccagctgac caatgcagtc actaaagcca tcaaggccca tccactcagc ataataaagc
     2581 ctaaggtctt gataccgtca ttagcttcaa agcccagcag ttgaagtgca gcgtaaagaa
     2641 taacagagcc aacggtcgaa atcatgccat tgatcagtaa tttttgcttt gcccaatccc
     2701 atctatcttt aatcggctta ccagataagg cctctgcaaa aataatattt gtagacaagg
     2761 caactaccat tagagacaca gcaatcatat aaggagccat gccaatacca ttggtcctaa
     2821 ccttatcctt gtccttctct gataacgcta ctggatcaga taccatatca gcattctggt
     2881 cctctaccca agccattgaa agctggtcag aagcttttga tagtgaggtc gttaagcttg
     2941 acagacctgt tgacagagtt gtcaagccat ctgtcaactg agagctgcca gaggagagct
     3001 gattggctcc aaaagctagc tgattagcgc ctactgtaag ctgctgtcca cctgctaata
     3061 attgactgga ttgatggtta agagctgttg cccctgtagc aagagtagac aggcctgctg
     3121 taagagcttc attcttagct gtcaattgat taaagccgcc agcaagagct tgactacctg
     3181 ataagagctg ggctgttgtc gctgagtgaa cagcccttaa accagttgaa agctctgaca
     3241 atgccttgcc tgtgctaggt aggatttgat cagcttgata agccagctga ttaacaagtg
     3301 ctttaaagtc cctcagttga tcagctacac cagcacttgt tgacatagcc tctagctcct
     3361 cagacatggc ttgcagtgat gtcaacatag cctttgctga tattgttact ttagttgaag
     3421 tattggaaat agctgagctc agctcctcct gctgctcaga gttgagacct tgataggtag
     3481 ctgtagcttg tagagcggct agctgattgt tcttgtcagc agtatcatct accacaagct
     3541 cctgcactaa acgcgtcata tcggctaaat gcttagcaat ggctcctgag tccacatttg
     3601 gtgccaaaga caaggaaaga ttggtcttta gctgctggat agcctgatta agctttggta
     3661 ggctagccat taaagcttga atattagctt gtttgtcttg agacagatca cttcctagag
     3721 ccaattgggt caagccagca tttaactgat tagcaccctt ggataaccga gaaacaccat
     3781 ctagatacgc tggcatatca gctgctagct gtcctaagcc cgcggtatca agctgaccaa
     3841 caccggctgt ataggcagct ataccactag atagattacc cgctccttga gacaagcgag
     3901 cacttgattc agacaaggtg ttcaaatgcc ttgacattag ctgactgctt gccctagcaa
     3961 ttactaagcc agcggctaat tgctgaccgc catttgaagc ttcctttaga ccagattgga
     4021 gctgatgcat gctcttaaaa acggaggtga tataggtctt ccttatattt ttagaaacag
     4081 cctctctcaa gtgattcata gcagattcac ccattttaga agcgataaag ctatggccct
     4141 tactagtttg atagctaaca atcagcttct ctggctgctg atctaatagc gtagtggcct
     4201 tttgtgacaa atcctttggc aacgtaatcg tcatataata acgacccttt tccaagccct
     4261 tttgtgcggt atctgcagcc acaaaatgat aatccaattc cttattttta gacatattgt
     4321 ctaccatatc gttaccaata gtcagtctct tgttattcaa gtaagcaggc ttatcctgat
     4381 tcacaactgc tacaggcaac tgatcaaccc gaccataagg atcccacatg gaccctaaaa
     4441 aggacaaatt atagagagct ggtactagag caaccccaat cattgtcact actagcttac
     4501 gatttttgat tattgctttt aatccttcta gcattatttt ttctccaaat agacatactg
     4561 ttcaaaaatt atgataaaat atattataca aataaagtga cattttacaa ggaaaaaata
     4621 aattttttag acataatgtc tacaagtgtt caaaaggaga taatgatgga tagccgcaag
     4681 cagcaaacca agaaggccat tcttaatgca atggtgagct tactaaaaac cgaaagcttc
     4741 gatgatgtaa caaccgttca gcttgctaaa atggcaggca ttagtcgttc tagcttttat
     4801 actcactata aagacaaata tgagatgatt gattactatc aacaaacctt ttttcacaaa
     4861 ttagaataca tttttgaaaa agaataccaa aacaaggagc atgctttttt agaagtattt
     4921 gaatttctca agcgagagca actactatct gctctgctat cctccaatgg tacccgagaa
     4981 atccaaagct ttatcattaa caaggttcgt ctgttgatca ctaccgatct tcaggacaag
     5041 ttcagtaagg acatcttgtc cccaaccgaa aaggaatatc gaagcatcta cctagcacat
     5101 gcctttttcg gtgtctgcca aagctggatt gctaaaggaa aaaaagaatc ccctcaggaa
     5161 atgactcgtt tcgtcttaaa aatgctatct aaaacatagt cctgcactaa tgatgtcaaa
     5221 tccagtacca aaaaacaact ttgtaaacta tttcttactg agtttataat gatctttatg
     5281 cctaacaata ccgacctcca atcgttagac ttttggtcta acctttgggg tcggtacata
     5341 aatcagctaa ccgctcaacc aaaaaagccc actgttgtgg gcttcttata atataaagtc
     5401 ttatcttaaa gcattttgtt gtagaattca acgacaagtg cttcattgat ttctgggtta
     5461 atttcgtcgc gctctgggag gcgagttaat gatccttcaa gcttttcagc gtcaaatgaa
     5521 acaaaagctg gacgtccaag agttgcttca actgcctcaa ggattgcagg aaccttcatt
     5581 gatttttcac gaacagagat gacttggcca atctcaacgc ggaatgatgg gatatcaaca
     5641 cgcttaccat caacaagaat atgaccatgg ttaacaaact gacgtgcttg acgacgagta
     5701 gttgcaagac ctaagcggta aaccacattg tcaagacgac gctctaaaag aagcatgaag
     5761 ttgaaaccaa gagttccttc tttgattttt gtagcttgta cgaataggtt acggaattgt
     5821 ttttccccca taccatatga aaagcgaagc ttttgcttct cagcaagttg caagccatat
     5881 tctgaaagct tgctacggtt gttagggcca tgctgaccag gtacgtagtt acgacgtgcc
     5941 aattccttac ctgtgcctgt caatgacaag ccaagacgac gtgattgttt ccatgatgga
     6001 ccagtataac gtgacatgta tcatgtcctc ctctaaaaaa tataacgagg aaataactgt
     6061 ttgaaaaatc ctgattcgtg caggaggttt tcgcctaaac agcaaaggtt actcaattta
     6121 gttaaccgcc tgttgacgag cttcatattt ttctgctgtt atttcacaca aaactaattg
     6181 taacatgaaa aaggtattga ttcaagtttt ttttacattt ttaatatcat atcatcaaaa
     6241 atggttagct gtaagctcaa agatgatgtt aatcatatgg caaacaagct tttacacaac
     6301 acttcccgag taaacaaggc tttttaatac cgataggaaa ttctttgaaa atagcatatt
     6361 atgttttgat atctaatacc gagagtctca gagtaactgc ttttcaagaa agctagtccc
     6421 tattattagt ccgggcttca ttcatttgct aataagttct tcaaggcttc aaattgattc
     6481 atatctttac acagctgtca acaaagtgta aagaaaaagc cctaaatggg cattgatttt
     6541 tcaatcaaaa taacgaatca gtgttttttc cgtcaaaata tctgaatagg tataagactc
     6601 aacataagaa ttattcgctt cccctgaagc atctgggttc ccctgatact caatgataaa
     6661 taaagaaggg taaacctcta tcaatctgcc aaccttattt ttttcacgct tacgaccatt
     6721 ttcaagtgtt aactcaacca actgaccttc atgagcctta atgtcttcct ttattttttt
     6781 cattttggca acatctgtaa atgcatcact cattctcttt ccctctttct tatctttcct
     6841 caaattgagc tattgtcgaa aatttattgt attccttttg aaacatcagc ttaactgtcc
     6901 cacgcgcacc tgccctattt ttctcaagaa tcacctcaat tgtattatcc tcaagagcct
     6961 cttctgtgct gtcgctttct ttacgataat aatcatctcg gtacaaaaat gcaacaatat
     7021 ccgcatcctg ctcgatagag ccagactcac gaatatcaga caaaactgga cgcttgtcct
     7081 gcctctgctc aacaccacga gaaagctgac tcaaagcaat aacaggcact tttaattcct
     7141 tagctaaaat ctttagctgc cttgaaatat cagaaacctc ttgctgacga ttttcaggtc
     7201 ttgtaccagt gatcagttgg aggtaatcaa tgacaattag ccctaagcct ccctcaacct
     7261 cctgagacaa tttacgtgcc cttgctctga tctcagtaat cttaatgcca ggtgtatcat
     7321 caatatagat aggtgcttct gccaaggctc cttgggcaat ggtcacatta ttccagtcct
     7381 gatcagtcaa ctgaccagtc ctcaagctat gtgaattgac cattccctca gcggccagca
     7441 tacgatcaac aaggctttca gctcccattt ctaaggagaa aatggcaact gctctctttt
     7501 gctttgtacc aacattttga gcaatgttta agacaaaggc tgtcttaccg actgcaggac
     7561 gagctgctaa aataatcagt tgatctgggt gtaaacctgt tgtaatcttg tcaagatccc
     7621 taaagcccgt tggtaaacct gtaacgtctg atgtctgctt agaacgaacc tcaagatttt
     7681 cataattaat ctttaaaacg tctgagatct tacgaaagcc actgcgattg ctatgctcac
     7741 tgatatcaac caaggccttc tcagcacttg caataatatc ctccgagtca gatgctcctt
     7801 cataggctaa gtttacagtc tctgtcaacc tattgatgat atcgcgtagc atagcctttt
     7861 cagctactat tttagcatag tattctgcat tggcactggt aggtacacta ttaaccagct
     7921 caacaatata agacaagcca ccaatatgtt gaaggtcccc ttgatcatca agaatcgtcc
     7981 ttaccgttgt tgcatcaata gcatcatttc gatcactaag ccttatcatt gccctgaaaa
     8041 tgaccttatg agaatactta taaaaatcct ctggaccgat aaattctcta acggtaatca
     8101 acttgtctgg ggaaataaag atagagccta gtacagactg ctctgccaat aaatcttggg
     8161 gttgaactcg taactcagca acttcaggca aactcagcac ctccaaatct tttttaggct
     8221 gatgtgctat gcctcagcaa tgtttagttt tatttcagct gtcacttctt tatgcagctt
     8281 aactggcact tcgataagac caatagcacg aatagggtga tctaaaacaa tatgacgctt
     8341 gtcaaccttg accttaaatt gcttttgcaa ttcctcggaa attttcttag ctgtaattga
     8401 gccaaaggta cgcccatctg gtccaacctt ttccttaaac tggacacgag ttttttcgtc
     8461 atctaagatt ttcttaacag ccttagcctc tgctaggatt tcagcctggg ctttttcctc
     8521 agctttttgc tgccctctta gctggccaat tgcttgactg ctagcttcct ttgctaaatt
     8581 tttcttaatc agaaaattct gagcataacc agtgggaacc tccttgattt ctcctttttt
     8641 tccttttcct ttaacgtcaa ctaaaaaaat gactttcatg actctacctc tcttgtttct
     8701 ttcattgtgt tatcaattgt ttctagtaac agctgcttag cctcgctaag actgatatgc
     8761 ttcatctgac acgctgctaa gttgaaatgt cctccgccgc caagcttttc catcattctt
     8821 tggacattga tcttactacg acttcttgct gatatagcaa tcttatcagc tcctgtctct
     8881 acaataacaa agctagcctc aatatgggcc attgatagta tggtatctgc tgccttacta
     8941 gcaatgacat tactataata ttgcccagca agcccagttg caacgataat ggagtcgcta
     9001 aggcgctcac ctctgagaat gatctcatta acctgcttat agtcatcaaa atcagttgct
     9061 gaaatatttt gaatttcgac gctatcacta cctctgcttc gtaaataact ggcaacatca
     9121 aaggttctac tggtgacacg tgttgaaaaa ttcttagtat ccagcataat accagccatc
     9181 aaaacacttg cttgaatctt gtttaagcgc ttcttcgcat tttgaaactg gattaattct
     9241 gtcactagct ctgcggcact gcttgcacca ctttcaataa aggtcaagat agcattatct
     9301 ggaaaatcat catctcttcg gtgatgatca acgacaataa catcttgaaa ttgctcgtaa
     9361 aattccttag acaaggttaa ggaaatctta gagtggtcca ccattactaa cagtgatcta
     9421 ggggtcgtaa gccccattgc ttgagaaata ctgataagac gtgtcttacc atcagcctgt
     9481 aagcgctcaa tagctctttc aatgtctgga ctcatctcat ccggattata gacagcaaag
     9541 ctgttttcaa taatgttact agcaaaaaat tgcatgccaa cagccgagcc taaggcgtcc
     9601 atgtccagtt tacggtgacc tacgataaac acattatcaa ccattttgat acggtctgaa
     9661 atagctgtca tcatggcacg cgtcctagtt ctagagcgtt taaccgtaga aacagagccg
     9721 ccaccaaaat agaccggatt tgtatggtct gcattttcac gaataacaat ctgatctccg
     9781 cctcggacaa gagcaatatt cagattctca agagcaacct gaccaatttg acaatgattt
     9841 tcctctccaa aggaaatgcc catacttagg gtcaatggta gctgcgcttc ttgggcttcc
     9901 tttcggaact gctctaaaat agaaaactta tcgtccatca gcccttttaa gatcttatag
     9961 tctgtaaaaa agtaaaaacg atccatatta acacgtcgat aaaatacctg cttagactcc
    10021 ataaactcag ctatgaaatt agccacaaat gaatttatct ttgacgtatc agcatcagat
    10081 aagtcatctg taatgtcgtc ataattatcc acagaaataa taccaataac tggctttagc
    10141 aagctagaat ctgctgattg tctactacca acagagctat caaaaaagta aaaaatacct
    10201 gatgccacat caatataaga cgtgtatcga ttgccagaaa cctcaaaggt ttgagaaata
    10261 tcacttttac gcttatcagt gagaagctgt tggatcatct gttcctgtaa aaaaccggcc
    10321 tcatcagtga aaatcagctc tgcgtaagga ttgtaccatt caatagcatt ggtttcttga
    10381 tcaaactgaa taacaccaac tggcatgtta tccagtaatg tttttaaatt attttctgtt
    10441 tgttcgttca atagctcaat gtggtctaaa tcagacaatt cgtaaacctt tttttgatac
    10501 caaagcaagg ccgcaacaaa caacaacact aaaaaaatag ctagtgtaat cagcattttt
    10561 gattgcatga ttctaacaca taaggctagt aagccgaata aaatcaactc catcataatt
    10621 aaatgaatgg tttcaaaacg aaatcttttc atctttaacc tcttaatccc gtattatacc
    10681 ataaaacagc cctgaaatac agagctgtca gtggttttga gattacaatt tgatgactat
    10741 tatgttttac ggcgagcctt tccattacct tcaaggtaaa ccattaaaat gctaatatct
    10801 gccggattta cacctgaaat gcgactagcc tgaccaatgg tttctggatt gattttctta
    10861 aatttttgcc ttgcctcagt agcaattgag tcaatagcgt cccaatcaat ggtcttagga
    10921 atccgctttt cctccatacg cttcatttta gcaacctgat caagggcctt tttgatatag
    10981 ccttcgtatt tgatctcagt ttctagtagc tcaatcagct tagcatctaa tccctcagca
    11041 gcaggaccta taaatgacac tacagtggca tagtcaacct ctggtcgacg cataaattcc
    11101 ttagctgtca ttgcgtccgt caaggactta aagccaagct tttgaacacg agcattggtt
    11161 tctttgattg gctttaattt gatactatct agcctcttta attcattgtc aaattgattt
    11221 ttcttgattt caaaggcaga ccaacgctca tcgtcaacca agccaatctg acgaccaatt
    11281 tcagtcaatc gcatgtccgc attatcatga cgaaggataa gacgatattc tgcgcgtgat
    11341 gtcagcaaac ggtaaggctc caaggttcct ttggttacca aatcatcaat cattacacca
    11401 atataagcgt cgctgcgctt taaaatgagc tcaggcttac cctgaacctt caaagcagca
    11461 ttgataccag cgacaaggcc ttgaccagca gcttcctcat agcctgaggt tccattggtt
    11521 tgcccagctg taaaaagccc tgaaatcatc tttgtttcaa gggtagcacg aagctgatga
    11581 ggtaatacaa tgtcatactc aatagcatag cctgttctca tcatctcagc attttcaagc
    11641 cccttaatag agtgaaccaa ttccttttgg acgtcctcag gaagacttgt ggatagacct
    11701 tgaacataga cctcctcagt gtcaaagcct tctggttcta aaaagagctg atgacgctct
    11761 ttatcagcaa atcgtacaat cttatcctca attgatggac aatagcgtgg gcccactccc
    11821 ttgacgactc ctgaaaacat aggtgctcga tataggtttt tagtgatgat atcatgacta
    11881 atctgattag tgtaggtcag ccagcaagga atctgattag ccaaataatc tttgtcctta
    11941 gacataaagg aaaaatgatt tggagtcaca tcaccaggct gaatctctgt cacctcataa
    12001 tcaatagaag aagccttgac acgtggtggg gttcctgtct taaagcggcc aatttcaaga
    12061 ccaagctttt tcaaattatc agctagtgtc actgaggcca agctgttatt cgggccagac
    12121 gaatatttca attctccaag gataatctca ccacgaagag ctgtacctgt tgttatgatc
    12181 actgcctgag ctgcatattt ttgccctgtt gctgtcagca ctccaacaac cctaccattt
    12241 tctactaaaa tatcatcaat catagactgg cgaagagtga ggttttcttg cttttcaaca
    12301 gtatgcttca tctcacgtgc atacaagctt ttatctgctt gagctcgtaa tgctcgaact
    12361 gccggtccct tacctgtatt gagcattttc atttggatat aggttttgtc aatgtttttc
    12421 cccatctctc caccaagagc atcaatttcg cgaacaacaa tacccttagc tgaccctcca
    12481 atagagggat tgcatggcat aaaagccagc atatcaagat ttatcgttgc taataaggtt
    12541 ttacacccca tacggctagc cgctaagctg gcttcaacac ctgcatgtcc tgctcctaca
    12601 acgatgacat cgtaggattc tgtaaattca tgtaccatat ctactccttt atctcaatat
    12661 gttttatatg ctgaggctgc ctgtcccaat gctttatagc cctttttaaa caactaggat
    12721 tgagccttat cttatctaga tcatcaagag caacccactc acaaacccta gtacaatcac
    12781 cctcaactac agaagggcta gaatcagata atagactcac aatataatga aactcaatct
    12841 gatgaaagtt cactccttct agacaaaatt gattttcaac cacaaaggct aactgagcaa
    12901 ctgaaacctc agctcctacc tcctctagaa cctcacgctt gacagcttct tctgtgcttt
    12961 ctccaacatg aatagcacca cctaaaagat aatagtcctc tttgggtgat ttggcaagat
    13021 aaatatagcc atccttaatt attaacgctg aagccctaac accaaagcta tggtctgcta
    13081 tccttgttct aaaatcctga accatctttt ctccttgaca ctgtttttaa gctataaaaa
    13141 tagtcaaaac ctgagaaagc tgtaagccaa aaagacttac aattcccatg agctttgacc
    13201 atcatcgtta ttgttaacct tattctatca aaatctgcca gcttgtcaag acttatcaga
    13261 tgacaaaacc gtcaacttta ttgacacatc tgtcaattaa catgtcaagc taaatatatt
    13321 gacaaggctc gccatcttta tacgccatat caataatacc accaccaaga cactcatgac
    13381 catcataaaa aacgactgct tgaccaggtg taatcgcacg ctgaggctca gcaaaaacaa
    13441 ccttagcttt gtctttcttg acatgaaccg tcaccttaga atctggctga cgatagcgga
    13501 actttgctgt gcattctaag gtgaattctt caggaacttc tcttgtaaac tgaatgacag
    13561 aagcgtcaag actagttgac attaaggact cgtggtaaaa gccttgacca acataaagga
    13621 tattttgtga aaggtctttt ccaacaacaa accaaggctt gttatctcca ccctgctgac
    13681 caccaatgcc aagtccccca cgttggccaa tagtataata catcaagcct gcatgctctc
    13741 ccatatcacg accatcaaca gtcatcatac gccccttttg agctggtaaa taatggctaa
    13801 gaaaggtctt aaaattcttc tcactaataa aacaaatccc tgttgagtct tttttctttg
    13861 ctgttgcaag gcctgcttgt tcagcaatag cacgtacctc tgatttttgc aggtgcccca
    13921 agggaaacat ggttttttgg agttgctctt gtgatagttg gcttaaaaaa taggtttgat
    13981 ccttaccctt atcaagacca cgcagcatat ggactacacc attctcatca cgtttgattt
    14041 gggcatagtg acctgttgcc acataatcag cacccaatgt catcgcataa tcaagaaagg
    14101 ctttaaactt tatctcctta ttgcacatga catcaggatt tggggtgcgt cctgaacggt
    14161 attctgctag gaaatactca aacactctat cccaatactc tttttcaaaa ttaacagaat
    14221 agtaaggaat accaatctga tcggctacgg ctgccacatc tttataatcc tcagtcgccg
    14281 tacaaacacc aaattcatct gtatcgtccc aattcttcat aaagacgcca atcacatcat
    14341 atccctgctc ctttaacagc aaggcagtta cagatgaatc aacaccgcca ctcatgccaa
    14401 caacaacacg tgttttcgag ttatctgtca tcatttattc tcccatcaat ataagataca
    14461 aggacatgag aaaaagaata gaacgaatca acttgcctaa acaagactct agcaaatggt
    14521 tcatttctat attttttgtc tttgtccaag tgttttctca aagctcgatt tgaaggtcga
    14581 tttgaagcgc cgctagacgc atgactatta taacagtatt gtctcttatt tccaacaata
    14641 tcttttttca taacaaacga catttgatta gcgatttgtt ataataaaaa ggataaaaag
    14701 agcatggagc atatatgaac acacaaaaat ttcaatcagt ttttgacatc attggaccag
    14761 tgatgattgg accatcgagc agtcataccg ctggtgctgt tagaatcgga aaggttgtcc
    14821 actccatttt tggagaaatt cctgatgagg tgacctttca tctatacaat tcatttgcta
    14881 agacctatca aggccatggt accgacaagg cactagtagc tggtattatg ggcatggata
    14941 cggataatcc aaacatcaag aattctcttg aaattgctca tcaaaagggc attaaaattt
    15001 attgggatat tttaaaggat agcaatgctc cccaccccaa tactgtaaag attagtgtca
    15061 aaaaggctga taaagcaatg agcattacag gtgtgtcaat tggaggagga aacattcagg
    15121 tcacagagct aaatggtttt tctgtttcct tgtctatgaa tactccaacc ttgattattg
    15181 tccatcaaga tatccccgga atgattgcta aggttacaga tatattgtca gctagtgata
    15241 ttaatatcgc tcaaatgact gtgactcgtg aaagtgcagg tgagaaagcc attatgatta
    15301 ttgaggttga ttctcgtgat tgtcaagttg ctgtcaagca gattgcaact attcctaatc
    15361 tgcataatgt caatttcttt gactagaaag gtatattatg ttttacacaa ttgaagagct
    15421 tgtcaagcag gctgatgata ggtttgatgg taatgtagca gagctgatga ttgctacaga
    15481 ggttgaaatg actggtcgaa gcagggcaga aatcctatcc atcatgtcac agcatttaca
    15541 ggtaatgaag gattctgttg tcagcggatt gacagcaacc aaatctatta gcggattgac
    15601 tggcggtgat gctcttaaga tggatcatta catcaaaaaa ggaaaggggc tttcagatca
    15661 aaccatttta acagctgtga gaaatgctat ggctgtcaat gagctaaatg caaaaatggg
    15721 acttgtttgt gcaaccccga ctgctggaag tgcaggctgt ctacctgctg tccttgctgt
    15781 tgctattgat aagctcaagc tatcagaaaa ggaacagctg gactttctct ttacagcagg
    15841 tgcctttggc ttagtcattg gaaataatgc ctctatctcc ggagcagaag gaggctgtca
    15901 agccgaggtg ggctctgcct ctgcaatgag tgctgcagcc cttgttaagg cagcaggtgg
    15961 taccgcttat caggctagcc aagcggtagc ctttgtgatc aaaaatctat tgggattggt
    16021 ttgtgatcct gttgctggct tagtcgaagt tccctgtgtt aagcgtaatg cattaggatc
    16081 aagctttgct cttgttgctg ctgatatggc attagcgaat attcagtcac aaattcctgt
    16141 agatgaggtt gttgatgcta tgtatcaggt tggtgccgca atgccaacag cctttaagga
    16201 gacagctgag ggaggattag cagcaacccc aacaggtaga cggtatagta aagaaatttt
    16261 cggagactaa tataatcaag taacgataga ctgaggagac gtcatgaaag caatcctatt
    16321 tgacttagat ggtactttgg tggattctag tataggaata ctaaatgcct ttgaatacac
    16381 ctttcaaaaa atgaaaatcc cttgtcctga tcatagcata ttatcgtctt acatcggacc
    16441 acccttagaa gcgacctttt cagcattttt taggaatcag catgatgtcg aggttgctat
    16501 aacacacttt agagattttt acagggaatt aggcatttac caagcaaggc tttattctgg
    16561 aatcacagag ctattagata atctctcgca agaaggtctt gacctctatg tgacaactag
    16621 taaatatgaa cctatggcaa ggcaaatgct tcaggattta acgattagcc attatttcaa
    16681 agctatccta ggctctattt ctaatcggtg tcacaagttg gatatcgtca aggcatgctt
    16741 acaagatttt gctattaata aaaaagaagc tataattgtt ggagatacca aatttgacat
    16801 gattggtggt aaacaagcag gcattacaag acttggagtt acttggggat ttggttgtca
    16861 agaggattta caagcacatg gcgcacaata cattggacac acaccccaag aggtgattga
    16921 gattatccag tcattgtaaa acgatactaa aaacctatca tcacacaaga tgataggttt
    16981 ttaacgctgt tatctgttct tagtagcccc aagctgataa gccctgtgca cgataggcat
    17041 ttaaggctga atttacctga tcctgaacgg ttgcagttga tccccagcct ggcatggttt
    17101 ggaataatcc tgaagcacct gaaggattag ctgcgttagg gtttccattt gactcacgag
    17161 cgataatggc ttcccaagta gcttgtggaa caccagtagc tgccgccatt tgagctgctg
    17221 cttcactacc gatagcccct gcggtattgc cgttagaaag gattactcca ttgctataag
    17281 ccactggtgt agctgcatac tgagcttgag gagcagcctc ttgcacagca ggactagcta
    17341 cctcagaagc tactgattcc tgagctggtg ctgcatcagc agaggaaggc tctgcctgct
    17401 cagctggctg ctccttggtt gcagcctttg ctactgttga tttttttgtt ttatgatgtt
    17461 tcttcacaac cttagtatca gaagctttag cataggaatc agtgtttaca ttttcacttg
    17521 aaaaagcaaa aactactgcg agcaaagcaa tagcagctgc tacaatgcca aaactaaaat
    17581 aacgttgttt caaaatgtct tgtttaaaca ttaaataaat acctcacttt tctctgttat
    17641 ccatattaac tgttaattat tacttgtcta tttaagatat attaaaaata ttacagcaat
    17701 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
    17761 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
    17821 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
    17881 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
    17941 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
    18001 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
    18061 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
    18121 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
    18181 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
    18241 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
    18301 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
    18361 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
    18421 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
    18481 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
    18541 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
    18601 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
    18661 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
    18721 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
    18781 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
    18841 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
    18901 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
    18961 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
    19021 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
    19081 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
    19141 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
    19201 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
    19261 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
    19321 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
    19381 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
    19441 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
    19501 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
    19561 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
    19621 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
    19681 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
    19741 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
    19801 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
    19861 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
    19921 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
    19981 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
    20041 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
    20101 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
    20161 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
    20221 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
    20281 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
    20341 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
    20401 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
    20461 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
    20521 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
    20581 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
    20641 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
    20701 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
    20761 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
    20821 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
    20881 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
    20941 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
    21001 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
    21061 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
    21121 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
    21181 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
    21241 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
    21301 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
    21361 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
    21421 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
    21481 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
    21541 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
    21601 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
    21661 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
    21721 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
    21781 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
    21841 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
    21901 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
    21961 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
    22021 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
    22081 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
    22141 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
    22201 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
    22261 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
    22321 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
    22381 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
    22441 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
    22501 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
    22561 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
    22621 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
    22681 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
    22741 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
    22801 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
    22861 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
    22921 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
    22981 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
    23041 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
    23101 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
    23161 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
    23221 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
    23281 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
    23341 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
    23401 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
    23461 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
    23521 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
    23581 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
    23641 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
    23701 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
    23761 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
    23821 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
    23881 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
    23941 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
    24001 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
    24061 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
    24121 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
    24181 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
    24241 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
    24301 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
    24361 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
    24421 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
    24481 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
    24541 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
    24601 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
    24661 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
    24721 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
    24781 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
    24841 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
    24901 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
    24961 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
    25021 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
    25081 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
    25141 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
    25201 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
    25261 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
    25321 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
    25381 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
    25441 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
    25501 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
    25561 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
    25621 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
    25681 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
    25741 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
    25801 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
    25861 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
    25921 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
    25981 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
    26041 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
    26101 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
    26161 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
    26221 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
    26281 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
    26341 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
    26401 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
    26461 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
    26521 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
    26581 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
    26641 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
    26701 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
    26761 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
    26821 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
    26881 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
    26941 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
    27001 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
    27061 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
    27121 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
    27181 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
    27241 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
    27301 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
    27361 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
    27421 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
    27481 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
    27541 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
    27601 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
    27661 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    27721 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    27781 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    27841 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    27901 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    27961 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    28021 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    28081 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    28141 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    28201 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    28261 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    28321 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    28381 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    28441 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    28501 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    28561 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    28621 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    28681 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    28741 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    28801 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    28861 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    28921 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    28981 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    29041 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    29101 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    29161 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    29221 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    29281 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    29341 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    29401 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    29461 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    29521 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    29581 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    29641 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    29701 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    29761 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    29821 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    29881 tcccctggct tgaatgaact gtgaactgcc ccccaaaagt tagacataaa atctaacaat
    29941 tggggggcta tttttatgac attgagttat gaagacaagg ttcaaatcta tgagctacgg
    30001 cacattggaa agtccattaa atgcttatca gaaaagttta gtattg
//
LOCUS       DARYJX010000030        29140 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYJX010000030 DARYJX010000000
VERSION     DARYJX010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29140
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..397
                     /locus_tag="TU257_001333"
     CDS             <1..397
                     /locus_tag="TU257_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834344.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TU257_001334"
     CDS             441..1106
                     /locus_tag="TU257_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834345.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDCIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TU257_001335"
     CDS             1103..2080
                     /locus_tag="TU257_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0834346.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TU257_001336"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TU257_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL0834347.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TU257_001337"
     CDS             complement(3407..3844)
                     /locus_tag="TU257_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL0834348.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4045..4737
                     /locus_tag="TU257_001338"
     CDS             4045..4737
                     /locus_tag="TU257_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834349.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5113..5589)
                     /locus_tag="TU257_001339"
                     /pseudo
     CDS             complement(5113..5589)
                     /locus_tag="TU257_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TU257_001340"
     CDS             complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TU257_001340"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL0834350.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7651..8349
                     /locus_tag="TU257_001341"
     CDS             7651..8349
                     /locus_tag="TU257_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0834351.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8561..8893
                     /locus_tag="TU257_001342"
     CDS             8561..8893
                     /locus_tag="TU257_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL0834352.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8908..10479
                     /gene="ffh"
                     /locus_tag="TU257_001343"
     CDS             8908..10479
                     /gene="ffh"
                     /locus_tag="TU257_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL0834353.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10632..11855)
                     /locus_tag="TU257_001344"
     CDS             complement(10632..11855)
                     /locus_tag="TU257_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0834354.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(12080..13051)
                     /locus_tag="TU257_001345"
     CDS             complement(12080..13051)
                     /locus_tag="TU257_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL0834355.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(13364..13804)
                     /locus_tag="TU257_001346"
     CDS             complement(13364..13804)
                     /locus_tag="TU257_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0834356.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(13801..14736)
                     /locus_tag="TU257_001347"
     CDS             complement(13801..14736)
                     /locus_tag="TU257_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0834357.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(15174..15587)
                     /locus_tag="TU257_001348"
     CDS             complement(15174..15587)
                     /locus_tag="TU257_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL0834358.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(15685..16440)
                     /locus_tag="TU257_001349"
     CDS             complement(15685..16440)
                     /locus_tag="TU257_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL0834359.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TU257_001350"
     CDS             complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TU257_001350"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL0834360.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            19132..20115
                     /locus_tag="TU257_001351"
     CDS             19132..20115
                     /locus_tag="TU257_001351"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL0834361.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(20320..21687)
                     /locus_tag="TU257_001352"
     CDS             complement(20320..21687)
                     /locus_tag="TU257_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL0834362.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(21937..22539)
                     /locus_tag="TU257_001353"
     CDS             complement(21937..22539)
                     /locus_tag="TU257_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL0834363.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(22540..23517)
                     /locus_tag="TU257_001354"
     CDS             complement(22540..23517)
                     /locus_tag="TU257_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL0834364.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(23520..24779)
                     /locus_tag="TU257_001355"
     CDS             complement(23520..24779)
                     /locus_tag="TU257_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL0834365.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(24791..25222)
                     /locus_tag="TU257_001356"
     CDS             complement(24791..25222)
                     /locus_tag="TU257_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0834366.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(25236..25829)
                     /locus_tag="TU257_001357"
     CDS             complement(25236..25829)
                     /locus_tag="TU257_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL0834367.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TU257_001358"
     CDS             complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TU257_001358"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL0834368.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TU257_001359"
     CDS             complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TU257_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL0834369.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(27770..28339)
                     /locus_tag="TU257_001360"
     CDS             complement(27770..28339)
                     /locus_tag="TU257_001360"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL0834370.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            28526..28711
                     /locus_tag="TU257_001361"
     CDS             28526..28711
                     /locus_tag="TU257_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL0834371.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            28766..>29140
                     /locus_tag="TU257_001362"
     CDS             28766..>29140
                     /locus_tag="TU257_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0834372.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         8613 a         6030 c         5495 g         9002 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgactgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatgt ttggcattaa acctaagaca gcttactgtc ttttcgatat aaacataaaa
     3961 agcttgaata ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta
     4021 tactgacaaa ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta
     4081 tcaaggcata ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt
     4141 tccaattggg aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc
     4201 atttttcaat tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt
     4261 cagttaagcg cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa
     4321 aaagaaaaaa taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat
     4381 gaaaggttgt ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc
     4441 ttttacgatg agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag
     4501 ccaacctatt tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt
     4561 gctatctatg ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa
     4621 aatggtctgc gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat
     4681 gacaatccgc gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc
     4741 tttgtattag cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc
     4801 attatttttg aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta
     4861 aaggtttttg aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg
     4921 gtggtttatt tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac
     4981 atcgctaaaa gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata
     5041 tgcttgatta accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa
     5101 tccaaataat cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg
     5161 cagtttattt ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc
     5221 tttttcttta tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat
     5281 attatcgtaa ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgactaaa
     5341 tatgtatctc cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac
     5401 attattccag aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa
     5461 aatatcagta atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat
     5521 tatgattttc tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc
     5581 ttcaatcaac caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg
     5641 aaggctttta aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct
     5701 ttttagtatc aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca
     5761 ctgttttcaa cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt
     5821 gctggtggtt tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca
     5881 attcgaactg agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata
     5941 ccatcaattg aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc
     6001 ataactccga cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca
     6061 agtcctgctt tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc
     6121 ttttctgctg tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga
     6181 cgccagacga cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta
     6241 aagagtgtat tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca
     6301 ttgtggtgag attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa
     6361 agcgttcctt gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg
     6421 taaacaaact cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga
     6481 agatctaaaa agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca
     6541 agcatttcca taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata
     6601 caggttaatt gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca
     6661 ccaccagaca aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt
     6721 tgcatgtcaa taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca
     6781 aagttcttca aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata
     6841 ccgtagagcc tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct
     6901 acaagatgaa agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc
     6961 tgctcatctg gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga
     7021 ccatattctc ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg
     7081 attagctgca tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga
     7141 tcaataccaa aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg
     7201 attggattga tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa
     7261 acaccaaact cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga
     7321 acgataattt tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta
     7381 tataccagaa ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa
     7441 ggcattagct tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg
     7501 aatgacctca actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat
     7561 tgatgatgag tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat
     7621 aaaaccatca tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac
     7681 gctattaaaa aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa
     7741 cgagatttag cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg
     7801 cttgtagagg agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat
     7861 cgcgtacaag agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga
     7921 cgtaagccat cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata
     7981 aatcaattgc acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca
     8041 gataaggttc ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc
     8101 aaaaaaactg atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc
     8161 ggcaaaagtc aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta
     8221 gaggtcgcta aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt
     8281 aggccctttg aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa
     8341 aataattaat cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc
     8401 tttttttcaa cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac
     8461 tattatcctc atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta
     8521 ccactgttaa aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa
     8581 ccgaatgaat gctctttttg aattttatgc tgccttattg actgataaac agatgaacta
     8641 tatcgagctc tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt
     8701 cagccgccaa gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga
     8761 aatgaagctt catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct
     8821 tgcaaaatat cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga
     8881 caacagagat taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag
     8941 gacgttttta agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg
     9001 accaaggaga ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc
     9061 tttatcaagc gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca
     9121 acgcaacaaa tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc
     9181 gcggagcttg ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga
     9241 gctggtaaaa cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct
     9301 cgtccattga tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc
     9361 ttgggacagc aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat
     9421 attgttgcca atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat
     9481 acggcaggac ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca
     9541 ctagctaaac caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc
     9601 aacgttgcct atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt
     9661 gacggtgata ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc
     9721 aaatttaccg gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg
     9781 tcaagtcgta tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa
     9841 tatgatgaga aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt
     9901 aatgacttta tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta
     9961 aaaatgattc caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag
    10021 caaattgctc gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca
    10081 gagcttttaa caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt
    10141 gaagtcaaca aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg
    10201 tcaggtgata tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa
    10261 aacatgccaa atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg
    10321 caaggtggtt tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt
    10381 ggaggtggtc taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa
    10441 gctaataaga ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg
    10501 tattctgcct ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat
    10561 cttttttata aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc
    10621 actattagct gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc
    10681 aagtgataaa aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga
    10741 ctgaaattgg acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata
    10801 ttcgcccaag ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac
    10861 tgaggataaa actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg
    10921 ccatatgaaa tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag
    10981 tccttgaatt ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt
    11041 cgcttttttt gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc
    11101 tcgtaattct tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg
    11161 ccataagtcg tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc
    11221 ttttcagtta aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa
    11281 gctatcacgc cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac
    11341 gcttcaatat cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat
    11401 agcttggttg ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc
    11461 agagccttgg aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata
    11521 ggatcaaatt taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc
    11581 gtaaatgcca ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc
    11641 atcgtcatac caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct
    11701 ccctgaaaaa taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg
    11761 ctctgcaaga ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa
    11821 ataccgattt ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct
    11881 aaatatctga tcttgaaata gatctgcttc tacttaattt attcgaaaaa tagtttgaaa
    11941 aataattgct ttttttgatt ttcaatttga ttatttttag ctgctcaaat gaataatcga
    12001 tttcggttta aataagttta aaaaatagga ctaattccta atgaaatcag gaattagtcc
    12061 tactactttt atctatttat cagttaccca ttaggctgtc aatcaatcct ctaaagaaat
    12121 caataatttg ctgaaggatt ccctgtccag tctttaaggc ttcagtagca tcaaagttca
    12181 cgttgatatt tttaaaggta gatccggcct tttcaacaat actatccttt aaagcattca
    12241 gcgttttggt gaagttttca ttggaaatca cgccactatt tgagaggtta agcgcgaaat
    12301 tgataataag gttaatctga tcaggtgtta ctgccttggt taacccataa tgatctaagg
    12361 tttctgttac aatttggcgc accttttcct cattaacccc ttctccagcc tttgcgacag
    12421 cagctttaat atcagtaagc gcaacattta gcttatctgc atcatagcct gttttacctg
    12481 cattttcggt attgatatta gatagggttg atagctcctc ttgtgccagc ttcttgtttt
    12541 cctctgggac tttggcacca tttttttcga gtgaataata aataccggct aaagctgatt
    12601 ctccagtaac tgggattggt gcagctacag taatattggc atgctcaatg cccaaggtca
    12661 cagcggcgtt acgatacata tcttgcgtca ccttagtgat attttcaggt gttacaatag
    12721 ttaccttaag cgtttcttta gctcccagct tttgaatcct aactgaggaa taaagctgta
    12781 ggctcggatc atctgctaca ttcatgatac tagcataggc agttgtattt agggtgctta
    12841 atttgttatc agaagcacta ttgtagtgaa gcaaggccaa ggtttgctct ctttgctcag
    12901 cagacagtga atagcctaaa acgtaatcag gctgaacata ggtttcatca attacctgtt
    12961 gaacattatt agctgcagcg tgtactgttt gaagcataaa taccgaagcc aaagccatac
    13021 tggctgctat taatttcttt tgataagtca tttttctacc tcttttgtgt tataaatttt
    13081 cctttacgag aatcctccag aaaagacgat taaagccaaa gtatctaggt gcctagtaag
    13141 accgttttac ttagctctgc aaagggcaat attcctagtc tttttcaaaa tctaacgcct
    13201 ctattgtagc atttttacct caataagacg attaaaaagc tgaaacaaag catagctaga
    13261 atggccaagc actattttta caacaaaaaa actagtgcat aatggcagct tagatgtagc
    13321 tactatcact agtccaatga ttatcttatg cagcaaccag tctttatgat ctgaggtttt
    13381 cttgatggtt attgtccttt aaatagaaat aataatgatc atcagttttg atgacatagc
    13441 catttttaac ctcattaatc acgtcctttt gatcaaactg gtagtcctta ggcggtaata
    13501 actctgagga aaaaaggcta tcataaggca cctcaccatt gtaaaaatgg taatggtcac
    13561 catgagaggt aacaaaacca tcatccgaga tagacacaat aatttgctct gctgctatcc
    13621 cctcttcctt gctaacttca ttaggacttt tgtcagtctc tttctttaag gctttgcacc
    13681 ttttttccaa ttgatgagat gattttagct tcttgcctgt gctatcttgg gctttaaagt
    13741 cacaagcgga caaaggaaat aatagtaaga tagtgaataa cgataaataa gcttttttgg
    13801 tcatgtttca ctctccaata cacgatatag tgtttctaaa ttcattttta aatgctctag
    13861 ataagttttt tgatcagctg gaaccacctc aagcgggctt aggatatcaa ttgctacacc
    13921 gttactttga gccaaggttt tggctagctt atctgaagca ttttcttcga cgaaaatcgt
    13981 cttcacatca tattttttga taaagcggtc aatttgagct aattggcgag gactaggctc
    14041 ttgctcagga gatatccctg caattcccaa ttgctttaga tcaaatctct tagctaggta
    14101 ggaaaaggct gtatgctgtg tcacaaaggt tttcctacct agagattcaa acttttcctt
    14161 ataggtcttc actaattttt gagccttagc cttaaaacgc ttagcatttt gcaaataaac
    14221 tgccttgtga gcaggatctt tttgactcaa taaagctgca atctgctctg cctcttgact
    14281 agctaagata ggatcagtcc aagtgtgagg atcatacaag gcatcggtat tcattccttt
    14341 ttttatggtg aagtgctcca agccttgaac cttgtctaat gttagatgtg atgtcccctc
    14401 catgactgct aatccctttt tttccagctg tggtgccaaa tccgcagccc aagcttctaa
    14461 tatcttggaa tggtaaataa agacatctcc atcgtaaacc ttagcaacaa ctgtcggact
    14521 tggctcatac gagtgtatgc tagtgttttg ggcaatgacc tgaacatcat ttaaatcccc
    14581 gcaaatctcc tttgtcatag cataaatagg ataaaagctt gtttttatga ccaaaccggc
    14641 cttcctactg ctagagctct gatgacaggc tgatagaccc aaaagtactg ctaatagtcc
    14701 tactgcgaca attgttttct tgaatcctct aatcatatct actctcttaa ctagttaatg
    14761 acctaaaaag gataccatga tttaactgaa atgtcaatat tttatcattt tagcgcacga
    14821 cgtacacgca tgaagaaaat gcatgtaagc cttttttagc cccatgcatt ttttaatcta
    14881 tttctagcgt tttgacattg caatatcatc agtttgtcaa tttcaatgtg atgacttcat
    14941 cacattttgc taaaaaggcc atagtgatga taaaaaaccg ctaccagaaa gcgtaaatgt
    15001 cttcttgctt ttgtcgtgat tttagtgaac cgcctaccaa ctgaactgat gctggcttaa
    15061 ccatttcctg gccaccatca aaagcctgcc tctcaattaa caagcttact caaggaagag
    15121 gtgactgagc catgcatccg tcttagttat gactaacagc ttatcttggc atttcattca
    15181 tgtaattcca gtggcaggcc atcaggatca aaaaagaagg tcatcttctt accagtataa
    15241 tcatcatacc taagaggctc gacagcaatg cccttagcca ttaattgttc aatataagct
    15301 tcaataggct taacatgaaa agctaaatga cgaagcccac aggcctcttt gtcatattcg
    15361 ggcctaccga tacgcttagg cggtgcctga taagctggat cagtcttttt attgccaaaa
    15421 atctctaatt caatggctcc acattttaaa tccaatttgt aatcatgtct atcaggccgg
    15481 tgattttcac gaataatctc aaagccaagc ttattgacat aaaaatcctt agagacctca
    15541 taatccgaaa caatgatagc aatatgatga atagccttaa gctccatatg atttagttcc
    15601 tttattaaat aaaaaaagtg aaacaaagca atgccaagat tactttgttt cacccctcgt
    15661 agcgacccct cgcctagatt aggcttaggt tgacatctga ttgtaagagt gattaaaggc
    15721 cttcaaaaca tcgtcaggtg ctttgttaaa ctcatactcg tttttgattg ctcctttgac
    15781 aatgattcgc tctgttgcct cataatccgt acaggtgacc aaggttacct cctttagccc
    15841 tggtgtgtca ttgataacat ctattctctc aggtgtgacc gtaaagacgg cattgatctc
    15901 gtactcgtaa atacgctcct tatctgtaag gtaaatagac atcccttctt ttgctctttc
    15961 aagcggtgag aataacattt cagaagagcc tgttagtcca aaaatatgat gactggctaa
    16021 ggagtaattg ttttctcctc ccataacctg gtcctctttc atggtaccag caccgtatat
    16081 aagctctgtg ttgccaagcc ctttaaagat tggtaggtta ataccaagct ctggtatggc
    16141 aatacctcct attactggaa gctgctgggc gtccatttga gcctgtaaga cactttcggt
    16201 gctaactggc tgaactgctt gaaaatcaaa gcttgacttt gcttccttat tctttttaat
    16261 cgtctttttt gaaacctttg taacttgata tttattagaa ttccaagcaa tcagggtgtt
    16321 tctaatgggc ttgttaaata acaaggctaa gcctatgatt aacaataaga cgactagaat
    16381 acctctagca aaggacatct ttcttcgttt ttgtcttctc ctgtgggttc tttttgccat
    16441 tcatttactc cttgctagaa tttattggtg cttctgttaa agctgtatca gtctgagcga
    16501 ttgctgttgg atcgttgtct tcagcctgta ccaaggtaaa ggtaacaatc ttagaatctg
    16561 tatctagcct cataacctta acaccaagtg ttgaacggcc agtctgagaa atacttgaaa
    16621 cattggtacg aataatcaca cccttcgttg tgatcaccat aatatcctca ctgccatcaa
    16681 cagtcatcag gccagccaac tggccatttt ttgcggtgat attagctgtt ttgattcctt
    16741 ttccacctcg acccttagtt gggtattcgg ctgcactggt acgcttacca tagccatttt
    16801 cggtgatgac taagacctct tgcttgtcat tgatacgaga agctccgaca acccaatctt
    16861 cctcacgaag cttgacacca cgaacacccg tagcgctacg ccccatgcct cgaatggtag
    16921 cttcattaaa gcgaacagaa taacctgatc ttgttccaat gataatatct tcctgaccat
    16981 ttgtcaagag aacattaatc agctcatctc cttccttgag attaagggct cgtagaccat
    17041 tctgacgaat attgctaaac tctgatacct cagttcgttt gacaatccct tgctttgttg
    17101 taaagaagaa atatttatca agaatgtctt cttttttagc attgataatt gtttgaatgg
    17161 tttcaccatc atctagcttt agtagattga taacaggaag tccttttgca gcacgtccat
    17221 attctggaat ctcataggcc tttaagcgat agacgcgccc aaaattggta aagaaaagca
    17281 atgtgtcatg tgtacttgtt gagacaagct cacgaacaaa gtcatcgtca ttgacacctg
    17341 ttccctgtac accacgacca ccacgctttt gagatcgaaa ctcgtcttga gcaaggcgct
    17401 taatgtagcc attgtttgat agggtgatca aaacatcttc ttcctcgatc aaatcctcat
    17461 cttctaatga caatacctca ccaatcatca attctgtgcg gcgaggatta gcgtacttgc
    17521 gcttgatctc ctccatttct tccttgatga tggcttcgat acgctctggc cttgccaaaa
    17581 tatctgccaa atctgcaatc aaagccagta ggtcatcgta ttctgattga attttatcac
    17641 gttccaagcc ggtcaaacgg cgaagacgca tgtctaaaat agcctgactt tggcgttcag
    17701 acaagtcaaa acgagacatc aattctgctt gtgcgataat atctgtctcg ctattgcgga
    17761 taatggcaat aacctcatct agatggtcaa gagcgataag taagccctct aaaatgtgtg
    17821 ccctagcttc tgccttgtcc ttgtcaaatt gagtcctgcg tgtaatgacg tccttttgat
    17881 gtagaatata attatcaata atctgtctca gtgacaagat tttaggaatc ccgccttcaa
    17941 tggctagcat attgaagcta aagtttgtct ggagacttgt caatttgaat aggttattta
    18001 aaatcacatt agcagatgca tcgcgacgga cttcaatgac aaatcgtacc ccttgtcggc
    18061 ttgattcgtc acgaacagct gtaatgccct caatacgctt ttcttgggct aagcgaacaa
    18121 tatgctcatg gacctttgtt ttattaatgc cataagggaa ttctgtgacg acaatccgct
    18181 cccgtcctgt actagtggtt tcaatctcgg tgcgtgaacg caaaacgatt gatcccttac
    18241 cagtctcata agccttatga attcctgaac gtcccatcac caaggcacct gtaggaaaat
    18301 ccggccctgg aagaacctcc attaaatctc tggtagtgca gtcaggattt tccatgacca
    18361 tcttaacagc gtctatggcc tcagctaaat tatgaggtgg aatattggta gccataccaa
    18421 ctgcgattcc ggtggcacca ttgaccaata aattggggaa gcgagccggt aagactaagg
    18481 gttctctttc attaccatcg tagttatcct gaaagtcaac agtattttta ttaatatcct
    18541 ttaagagctc tagcgcgatt ttgctcatac gagcctcagt ataacgctga gccgcagcac
    18601 cgtcaccgtc catagaacca aagtttccat gaccatcgac aagcatgtga cgatagctcc
    18661 accactgggc catacggacc atcgcttcat agatggacga atccccatgt gggtggtact
    18721 tacccatgac atcaccggta atacgagcag attttttatg tggcttatca ggtgtgacgc
    18781 ctagctcatt catgccataa aggatacgac gatgaacagg ctttaagcca tctcgtacat
    18841 ctggaagtgc tcttgctaca ataacgctca tagcataatc aatgaaactc gttttcatct
    18901 cacttgtcag attgacgtca actaaatgtt tatcttgcat ttaaggaatg ctccttttct
    18961 agtcaatact cttttaatta taccataaaa tccttatttt ttctgattgg aaacgctgtc
    19021 cgaaaacaat tttcataatt tggtcgaata tcatgacaaa gacattaaaa tgtgttaaaa
    19081 taagatcgta tgagcaattt gctctaacta aaatgaagga gatgtttaga aatgactgca
    19141 actaaacaac ataaaaaagt catcttggtt ggcgatggtg ctgtaggctc ttcttatgcc
    19201 tttgcactag taacccaaaa tattgcccaa gagcttggta ttattgatat ttttaaagaa
    19261 aaaactcaag gagatgctga ggatttaagc catgcgcttg cctttacctc ccctaaaaag
    19321 atctatgctg ctgattatgc tgactgtcac gatgctgacc tagttgtttt aacagctggc
    19381 gctcctcaaa agccaggtga gactcgtctt gaccttgttg agaaaaatct acgtattaat
    19441 aaagaagtgg ttactcaaat tgtggcctca ggctttaagg gaattttcct tgttgctgct
    19501 aatccggtgg atattttgac ctattcaacc tggaaattct caggtttccc taaggaacgc
    19561 gttatcggtt ctggaacatc acttgactca gcacgcttcc gtcaggcact tgctgccaaa
    19621 attggtgtag acgcacgttc tgttcatgcc tacatcatgg gtgagcatgg agattcagaa
    19681 tttgctgttt ggtcacatgc taatgttgca ggggttggat tgtacgactg gcttcaagct
    19741 aatcgtgacg ttgatgaaca aggcttggta gacctcttta tctctgtacg tgacgcagct
    19801 tactctatca tcaataaaaa gggtgctacc ttctatggta ttgcagtcgc cctagcacgt
    19861 attacaaaag ctatccttga tgatgaaaat gcagttcttc cactttctgt tttccaagaa
    19921 ggccaatacg aaggcgttga ggattgctat atcggtcagc ctgctattgt tggtgcctat
    19981 ggtattgttc gtccagtcaa tatcccattg aatgacgctg agcttcaaaa aatgcaagct
    20041 tcagcaaacc aattgaagac tattatcgac gaagccttct ctaaagaaga gtttgcgtct
    20101 gctgctaaaa actaattaaa aaatgaatgt gttagatctt gctctaacgt tttggaatca
    20161 ctacaaaaag cctaatccaa tcggataggc ttttttcatg cgtctaacag cgaggtgcaa
    20221 gacaaagcac gctttcatta agcatcgtgt gtgctatgct tatagtctta agtcacaaaa
    20281 aagacaacca gctttatgag ctggctgctt attagcttgt tattcagcac caagtgctgc
    20341 cattgtaatg tagttatatg gcttgttaaa gtgcggtaag aagaaaatat cagtcaaagc
    20401 taatttctca atggtcactc cttcttggat agcaagtgag aacatatgaa ttcccattga
    20461 aatatcttca tgtgaggcca tttgagcacc tagaatacga cgtgattctt tatcgtagac
    20521 aatcttaatg gttacttgga agttaccatg ctcgataaat tctggttttt gattgtcagt
    20581 gtattctgtt actgctgcat caaagccaag gcattttgct ttctcaagag ttaagccagt
    20641 tgataccatg tgcaagccgt agatagagat accatttgat ccctgcacac caataccctc
    20701 aagagctgtg ccacaagcgt tatgagctgc gacaatccct gtacgaacag catttgaagc
    20761 aagggcaata taattggtat cgcgagttgc gttgtcatag atggttgcac aatcaccgat
    20821 tgcataaatc cctggaatag atgtttcttg gtgtttgtta acaaggaagg caccattacg
    20881 gaaaagctca atcttgccag caccaagagc tgtatttgga cggaagccaa ctgcaaggat
    20941 aaccatatca acatcatatt cattcttatc agtgattagc ttttcaacct tgccatcacc
    21001 agcaacctct ttgacagttt ccccaaaggc caactgaata ccatgctctt ctaggttttt
    21061 agacatgaca tctgtcaaat cacgatcata gtagcctgct agacaagtat ccgcaacatc
    21121 aatcagaata acctctttgc ccttacgttg gaaggcttct gcaagctcta caccaatgta
    21181 gcctgcacca acgactgcaa cgcgcttaat gtctttgttt tctaatttcg aaatgacatc
    21241 tgctgaattt tggtacaatt taacgaattg aagattttca agtgttgctt caaactctaa
    21301 tgagccctct ttgatttctg cacctttaat tggtggcaag ataggctgtg aaccagttgc
    21361 aaaaattaat ttgtcatatg actcaacatg ctctttgcca tcaacaaggg ctgtcactgt
    21421 tttagcatcg tagtcaatag attgaactgg tgattccatg taaaccttag caccaaggga
    21481 ctctagctct tccttatttg agtagaataa gccctctggg ccagaaattt gttcgccaat
    21541 ccaaagtgcc ataccacagc ctaagaatga aatatttgag ttttggtcaa atacaacaat
    21601 ctcattagca tcaccatagt ttgttaacat agtcttgata catgccgtac ctgcgtggtt
    21661 tgcaccgata acaacgattt tactcatatg attatgttcc tcatttcaca atttatatta
    21721 ggtctctatt ataacacagg gaaaaagcgc ttccaactaa aatgctcatt tttcttgctt
    21781 ttttataccg ttttttagtc aataaataag acagcctatc atttgttgaa gggtcgtaca
    21841 aagaccggtt tgcttcagtt aagtcaagac gacattctta ttcaactatt ttcccaaatt
    21901 cattacatga ttaagaccat tttttgtcgt taacttctaa aaaagactca taagctcaat
    21961 caggtaaaga ttgacatgta cctcttgagc ataataaata ttgccgccgt tgcaataaag
    22021 ctttccacca gagaggaggg ctaaggggtg gtaataaaaa taggtttttc cagtagtatt
    22081 tcctaggctg ggtgcaacga cagttctaga atagttagtg gctagttcaa ttgtatgctg
    22141 accgccattt ttagcaacgt aatcaatata ggcggttcca aaattgtaag cttgaacagc
    22201 tgtccaaggg tctacgccgg ctttttctgc taaagctaaa ttgtgagata gcaatctgac
    22261 accatactca atgctagatt gactatcggt gatcgaatcc cttatgccag agctgctttc
    22321 gcttgactgc ataacgtcag cttctcctcc cttagtttcc gtgtatatca tggctagtac
    22381 cagatcgacg tctgctttgt taccgttttc tgctaaaata cgctctactg ttggcttgta
    22441 ttgtaggact ctgtgcacat tcttatgaat ggtaactgct tcgtacaggc aaaaaatgag
    22501 gacggctaat cctaagatac gctttaacac tctaaacatt tagttatttt tgatatcctc
    22561 tatatttttt atcaatatgg aataggttcc gttgtcattc aagataaact ctactgactc
    22621 agcatcttga taaactgcat tagggacaag aagctcaatt ccatttgaca gcgacagctt
    22681 ttgcgtctct agctttttta gctgtctaga atgatcaata tcactgacct gaattggttc
    22741 gggaatcatt tccttgacct gatccacaaa ggttaacctt gcagtcaggt tctggtcaaa
    22801 taattgatct gctagctttt ctggagatag agctgtttct tcttctagat ttttagccag
    22861 tgctactttc atctttgatt gaaaagcaaa gtcatcttgg ttaaaattct cggcaacctt
    22921 ttgagcggtc tgctcaagca tttgaataga ttttttgaca gattgctcag gtgttacctt
    22981 tagcagcttc tcagaaaagt aatgagcaaa gcttccattg tgcttcatgc gtttttcgat
    23041 taagtagtaa tagcctgttt gacggttaat gaccaaggct tcatcaggtg cctgagtagg
    23101 gcttggcaaa ttattttgcg tgatcgtaat aggattttca tgatcgtctg atagatgggc
    23161 aaaatgctct tttagggcaa tgcgtaaaaa ggccagataa ggcactcctt ccttatcaaa
    23221 ctgaataaaa accaaatcgt ttgtcttttg atgttcagaa gcgacaaatt cttccttcca
    23281 aagcttggca attgttactg atgtttccaa aagctctgta ccgattgtgg taaaaaaagc
    23341 atgatcagct tctaattgcc cacgtttagc gtcgtcagaa aaaaccttgg ctaatttttt
    23401 gcgaaaatac tcatcaattc ttggtgttat agctactaaa gcatctgata agatcagctc
    23461 ggtatcgttt ggtgtgaatt ggtggatcac aattcctttt atataaatat ctagcattgt
    23521 tagttcttct tgtataatgg gaaggcgtca gtcaatcggc gaacctcata acggacctct
    23581 tcaaggattt caggctgctg gtggttaacc aaggccttga taattaaatg agcaatagtc
    23641 ctactttcgt ctactcccat tccacgactg gtaatggcag cgcagcctat gcgaatgcct
    23701 gatgttttaa agggagatag ggtctcaaaa ggaatagcat ttttgttaag ggtaatatta
    23761 acctcatcaa gcaaggcttg agcaagcttg ccattttcaa tcaccttagt cacatcaaca
    23821 aggaaaagat ggttatctgt accgcctgag atcagacgaa aacgatcatc cttggcaaaa
    23881 acctctgcca ttgctgctgt atttgctata acagcccttg catagtctgt aaaggcagga
    23941 tcaagcgcct ccttaaacgc aacagccttc gctgctatga catgctccaa aggcccaccc
    24001 tgtagaccag ggaaaatagc tgcattcatt ttccttgaaa ttgcttcatc atttgtcaaa
    24061 agcaggccac cacgaggacc acgaagggtt ttatgagtgg ttgaggtcac aatatgagca
    24121 taaggtactg gattttgatg cagacctgct gcaaccaagc ctgcaatgtg tgccatatcc
    24181 accatcaaat aggatcccac ctggtctgca ataaaacgaa attgctcaaa atcaatctgc
    24241 cgagaatagg ctgaggcacc tgcaacaatc aacttaggct gaacagcctt agcttgcttt
    24301 aggatagctg cgtagtccag cttttcagtt tccttatcga cagtgtagcc gacaaattga
    24361 taggtttttc cagaaaaatt gacaggtgag ccatgtgtca agtgacctcc agctgccaaa
    24421 tccataccaa gcacagtgtc accagcatta atcagtgcca tataagcagc agcattggcc
    24481 tgactaccag aatgaggctg aacgttggca taggctgcac caaagagctt tttggcacgc
    24541 tcaatagcaa ggctttcaac aatatcaaca tactctgtgc cgccataata acgcttgctt
    24601 ggatagccct cagcgtattt gttggtcaag acagagcctt gtgcttgcat aacagccttt
    24661 gagaccatat tttcagaagc aattagctca atattatgct cttgcctgtc ctcctcggcc
    24721 tgaatagcct cccaaagctc ctgatcatag tctttgtagt tctcgttgtt aaacatcatt
    24781 attgtctcct ctataatagc ttcataaatc gtaattgtgt cttatcatct acatagctca
    24841 gcttacggta aaaggcatgt gcctcggtcc tgtgactagc agaattaagc cgaataaagc
    24901 ttactttctc ctgcttagcc ttctcctcta aagcagctag taagcgacga ccgatacctc
    24961 taccttgatg gtccagcctc actgctaagg ccaaaatatt aaagcctttt tccgagtaaa
    25021 gcgactcgta gcattcagca tgcagatagc ctaagagcag attggtctta gtatcagcat
    25081 agcccagcaa ataatgatgc ttatcggatc ttagtttttc caattggctt tttgtcaatt
    25141 caagagaaac cttgtacccc aaggattgat cattaatgtc acaaatagct tgacaatctg
    25201 tttgatctag tggtcttagc atagccttac ctcctctaaa atggcagctc tggaacctta
    25261 gctaataatt gctccttagt aatagcacct tgtcgtaaaa tactgacctt aggtgacgat
    25321 aaatccaaaa tagtagaatc cttccctgtc aaataggcat catcagcata accatcaacc
    25381 tttccatcaa atgccttgac aatgtcatta aagcattttc cactctttga gcctgacagg
    25441 ttagcagatg gcccaatcaa gggacccgtt gctctgataa ttttagctgt gagagggtga
    25501 ctgggtagtc gaaagccaac tgtttttagc ccagaattaa tccaataggg tgtctgggca
    25561 ttggctttta ggataatcgt aagtggacca ggtaaaaaag cctcgtacag cttgttaaga
    25621 taggcaggct gctgcttaga aaaagccaaa atactctcaa aatcagccac attaaggttc
    25681 atagccttgt cgcgaggcct ttttttgaga cgataaacag cattaacagc ctcttcattt
    25741 aaggcctgag caaaaagacc ataaactgtc tcagttggta aaataagagc tccaccagcc
    25801 ttaattgtct ctatcaaatg tgttatcatc aacaaccacc attctttctt tacccagcat
    25861 atccttaagc actctgatac gcttttgagg gaaacgcttg gataagagcc tttttaagcc
    25921 ttctccctgc ttgtagccta tttcaaaata gagcttacca cttgtcgtca gataagcact
    25981 agcttgttcg ataatgcgtc ggtaaataga aaagccattt tctgcagcaa ataaggccaa
    26041 atgcggctca gattgataaa cattcaagcc aacctcgtcc ttatcctcat aggcaatata
    26101 gggagggtta gaaacaatga tgtcaaactg ccctgatagc ttgctaaaaa ggtctgactg
    26161 ctcaaaggct atctctacat gatgatctaa agcgtttgag taagcaaggc tcaaggcatc
    26221 agctgaaata tcagaggctg tgacctgcca gttaggtctt gcttttttta aagcaattgc
    26281 aatagcacca ctgcctgttc caatgtctaa aacggatttg cgagtagcgt cattttcctt
    26341 caagataagc tcaactaatt cttccgtctc tggtcttggg attagcacgc gcgaatccac
    26401 tgcaagcacc agatctctaa aataagccct gcctgtgata tattgtggcg atacatgctg
    26461 gctaagcgct aaaaaaatcc gctctaataa ggcttgatcc tctgaagtga cctcttgatt
    26521 ttgatgaagc aaaaagtcaa ggcttgtcca ctgctttaat tctttaaaaa cataggcgag
    26581 gttttcacga tcctcaccta tgttttctag cctgtcttcg taggctctta gttgcttagc
    26641 atagttcatt ggttatttag cgattctaat ttctgagttt gatcatatag cactaaagcg
    26701 tcaacaatct cgtctaactt tccagacaaa atggtgtcta atttttgcag ggttagaccg
    26761 atacggtgat ctgtcacacg attttgtggg aaattatagg tccgaatccg ttcagaacga
    26821 tcacccgtac cgatagttga tttacgctct gcgtcctgct cgtcctgtgc gatctgtgca
    26881 aaatgatctg ctacacgtgc ccgaataatc ttcatagcct tgtcacgatt cttttgctgc
    26941 gttctttcct cttgcatctc aaccttgatg tttgttggga gatggacgat acgaacagcg
    27001 gttgccacct tgttgacatt ttgtccgcca gcaccagaag catggtaaat atcaatacga
    27061 aggtcctttg gatcaatgtc gtactcaact tcttctacct ctggcatgac taagacagtc
    27121 gcagttgaag tatgcacgcg cccttggctt tctgttacag gaacacgctg tacgcgatga
    27181 gcacctgatt cgtattttag cttggaataa acagattgtc ctgaaaccat agcaacaacc
    27241 tctttaatcc ctccaacacc attataggaa gcctccatta cctcaaagcg ccagccttgg
    27301 ctttcggcaa atttttggta catggctaag agatcaccgg caaatagagc agcctcatca
    27361 ccacctgcgg caccacgaat ttccaagata atatttttat catcatttgg atctttggga
    27421 agcagcaaaa gctttaactt gtcctcatag gcttccttgg cagacttggc ctcttttagc
    27481 tcctccttgg ccatctcttc aatgtcagga tcgccgccgg cttccttaat catctcctca
    27541 gcgtcatcaa tggattggat aatagcctta tactgacgat aagctgctac tgtttctcgt
    27601 gtgctagcct cttcctttga cagagccata aaacgtttgg tgtcagaaac aacctccgga
    27661 tcacttaata attcgcctaa ttcttcataa cggtcctcaa cggcctgtaa ttgatcataa
    27721 atattcatta gggggtattc tctcctcttt ttacttgttt tagttgttat tagattggtg
    27781 ggtgaaaata atgcttgcga caaactggaa tataggtctc attgccacca atttgaatct
    27841 gtgctccctc ataaacgggc ttaccatgtt ctgttcgcaa taccatagtt gcttttttgc
    27901 tgcaatattg acagatggtt tttatctcat caatcttatc agctaacagt aacaggtatt
    27961 tggagccttc aaacaattca ttttgaaaat cattttttaa gccaaaggcc atcactggaa
    28021 catttagctc atcaaccaca cgtgctaaat catagacatt ttgcttgctt aaaaattgac
    28081 attcgtcaat caagacgcaa tagggcttct cctgcaattc agcaataaat gcaaaaatat
    28141 ccatatcatt cgaaattggt acagcctcac gacgcatgcc aatccgacta gaaacaatgc
    28201 caaagccatc acgtgtgtct agcgcacttg tcataatcac aacaggcttc ccctgttctt
    28261 cataattgtg tgctaccttc aagatttcaa tggtctttcc tgaattcatt gttccatatt
    28321 tgtaatataa ttgagccaaa atggagattc ctaccttctt cttttgtcct acttattcta
    28381 tcatatttgt ccctatttgg cgattgcctt atctgaaaat cttattttca caacagctaa
    28441 atcctgtgct gttgagctaa ggttaggctt tttgaagctg acatgctaca atagaggtat
    28501 cattaaaaaa aggagattga ctattatgcc atttgtaacg attgacctgt ttgaggggcg
    28561 tagccaagaa caaaaaattg ccctagcgcg tgaggtgaca gaggttgttt ctcgtatcgc
    28621 acaggctcca aaagaagcga ttcatgttgt aatcaatgac atgcctgagg ggacctattt
    28681 cccgcatggt gagatgaaaa ccaaagccta atgcctaagt cccacttatc taggtgggct
    28741 tttcctattt gaaaaggagg gcctgatgat agctactgat cagatcaaga tgatgggaac
    28801 aatcattgat atttgcattg actcatcaaa agcaaagcag caagcagcta ctatccgaga
    28861 gctactaacc ctttacaatc accgtttttc ggccagtgac gacagctctg aattaatggc
    28921 aatcaaccat atggcaggta ttcagccagt gcgtgtgcat tcagatttgt ttgacttaat
    28981 ctcaatcgga aaagagcata gcttggctta tccaagcaac cttaatatca cacttggtcc
    29041 tttagtgcaa agctggcgca tcggcttttc agacgctaag cttccagatg aagcaactat
    29101 tgatcgcaga ctaagactaa ccaatcctaa tcatatcatc
//
LOCUS       DARYJX010000031        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYJX010000031 DARYJX010000000
VERSION     DARYJX010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(298..813)
                     /locus_tag="TU257_001363"
     CDS             complement(298..813)
                     /locus_tag="TU257_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0834373.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TU257_001364"
     CDS             complement(815..2326)
                     /locus_tag="TU257_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0834374.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TU257_001365"
     CDS             complement(2316..3041)
                     /locus_tag="TU257_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL0834375.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TU257_001366"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TU257_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TU257_001367"
     CDS             complement(4136..4642)
                     /locus_tag="TU257_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834376.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TU257_001368"
     CDS             complement(4644..5570)
                     /locus_tag="TU257_001368"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834377.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TU257_001369"
     CDS             complement(5712..6134)
                     /locus_tag="TU257_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834378.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TU257_001370"
     CDS             complement(6457..6717)
                     /locus_tag="TU257_001370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834379.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TU257_001371"
     CDS             complement(6732..8540)
                     /locus_tag="TU257_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834380.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TU257_001372"
     CDS             complement(9181..10080)
                     /locus_tag="TU257_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL0834381.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TU257_001373"
     CDS             complement(10092..10901)
                     /locus_tag="TU257_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0834382.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TU257_001374"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TU257_001374"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL0834383.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TU257_001375"
     CDS             complement(11736..12476)
                     /locus_tag="TU257_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834384.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TU257_001376"
     CDS             complement(12480..13778)
                     /locus_tag="TU257_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0834385.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TU257_001377"
     CDS             complement(13790..15136)
                     /locus_tag="TU257_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0834386.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TU257_001378"
     CDS             complement(15581..17026)
                     /locus_tag="TU257_001378"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL0834387.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TU257_001379"
     CDS             complement(17628..18341)
                     /locus_tag="TU257_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL0834388.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TU257_001380"
     CDS             complement(18469..18975)
                     /locus_tag="TU257_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL0834389.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TU257_001381"
     CDS             19358..19636
                     /locus_tag="TU257_001381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834390.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TU257_001382"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TU257_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL0834391.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TU257_001383"
     CDS             complement(21225..21671)
                     /locus_tag="TU257_001383"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL0834392.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TU257_001384"
     CDS             complement(21873..22640)
                     /locus_tag="TU257_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL0834393.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TU257_001385"
     CDS             complement(22802..24598)
                     /locus_tag="TU257_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834394.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISASKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TU257_001386"
     CDS             complement(24598..26307)
                     /locus_tag="TU257_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834395.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TU257_001387"
     CDS             complement(26300..26749)
                     /locus_tag="TU257_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0834396.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TU257_001388"
     CDS             26959..27978
                     /locus_tag="TU257_001388"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0834397.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8374 a         6756 c         5153 g         7750 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagacag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggc accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt gaagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYJX010000032        26418 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYJX010000032 DARYJX010000000
VERSION     DARYJX010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26418
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            79..384
                     /locus_tag="TU257_001389"
     CDS             79..384
                     /locus_tag="TU257_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834398.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            451..2433
                     /locus_tag="TU257_001390"
     CDS             451..2433
                     /locus_tag="TU257_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834399.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNII
                     YNSLFSSEAIKKINDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIV
                     FLLIYQYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQV
                     ELLYIGIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            2433..3056
                     /locus_tag="TU257_001391"
     CDS             2433..3056
                     /locus_tag="TU257_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0834400.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENKTVYDNLRLIN
                     KDKKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTGALD
                     SEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
     gene            3053..3562
                     /locus_tag="TU257_001392"
     CDS             3053..3562
                     /locus_tag="TU257_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834401.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            4080..4877
                     /locus_tag="TU257_001393"
     CDS             4080..4877
                     /locus_tag="TU257_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0834402.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            4878..5705
                     /locus_tag="TU257_001394"
     CDS             4878..5705
                     /locus_tag="TU257_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0834403.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            5705..7162
                     /gene="ftsY"
                     /locus_tag="TU257_001395"
     CDS             5705..7162
                     /gene="ftsY"
                     /locus_tag="TU257_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL0834404.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            7451..8290
                     /locus_tag="TU257_001396"
     CDS             7451..8290
                     /locus_tag="TU257_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0834405.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            8295..10157
                     /locus_tag="TU257_001397"
     CDS             8295..10157
                     /locus_tag="TU257_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL0834406.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            10184..11605
                     /locus_tag="TU257_001398"
     CDS             10184..11605
                     /locus_tag="TU257_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0834407.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(11790..12605)
                     /locus_tag="TU257_001399"
     CDS             complement(11790..12605)
                     /locus_tag="TU257_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL0834408.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(12605..13507)
                     /locus_tag="TU257_001400"
     CDS             complement(12605..13507)
                     /locus_tag="TU257_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL0834409.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            complement(13548..13703)
                     /locus_tag="TU257_001401"
     CDS             complement(13548..13703)
                     /locus_tag="TU257_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834410.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            13875..14597
                     /locus_tag="TU257_001402"
     CDS             13875..14597
                     /locus_tag="TU257_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834411.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            14581..15906
                     /locus_tag="TU257_001403"
     CDS             14581..15906
                     /locus_tag="TU257_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL0834412.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            16065..16937
                     /locus_tag="TU257_001404"
     CDS             16065..16937
                     /locus_tag="TU257_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL0834413.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            17007..17870
                     /gene="pstC"
                     /locus_tag="TU257_001405"
     CDS             17007..17870
                     /gene="pstC"
                     /locus_tag="TU257_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0834414.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            17863..18678
                     /gene="pstA"
                     /locus_tag="TU257_001406"
     CDS             17863..18678
                     /gene="pstA"
                     /locus_tag="TU257_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0834415.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            18680..19432
                     /gene="pstB"
                     /locus_tag="TU257_001407"
     CDS             18680..19432
                     /gene="pstB"
                     /locus_tag="TU257_001407"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0834416.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            19708..20034
                     /locus_tag="TU257_001408"
     CDS             19708..20034
                     /locus_tag="TU257_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834417.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            20202..22334
                     /locus_tag="TU257_001409"
     CDS             20202..22334
                     /locus_tag="TU257_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL0834418.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            22321..22758
                     /locus_tag="TU257_001410"
     CDS             22321..22758
                     /locus_tag="TU257_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL0834419.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            22822..23094
                     /locus_tag="TU257_001411"
     CDS             22822..23094
                     /locus_tag="TU257_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL0834420.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            23372..24304
                     /locus_tag="TU257_001412"
     CDS             23372..24304
                     /locus_tag="TU257_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL0834421.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            24301..25080
                     /locus_tag="TU257_001413"
     CDS             24301..25080
                     /locus_tag="TU257_001413"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL0834422.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            25102..25506
                     /locus_tag="TU257_001414"
     CDS             25102..25506
                     /locus_tag="TU257_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL0834423.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            25503..25928
                     /locus_tag="TU257_001415"
     CDS             25503..25928
                     /locus_tag="TU257_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL0834424.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(26054..26335)
                     /locus_tag="TU257_001416"
     CDS             complement(26054..26335)
                     /locus_tag="TU257_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL0834425.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
BASE COUNT         7795 a         4821 c         6090 g         7712 t
ORIGIN      
        1 ttatttagat tgttcaaata tttttaacaa tctatccaat gagaactaat atgaaaaatt
       61 ggtgacaaaa cattagtttt gcttgctgta agcactttaa gttttggatc tgctgctaca
      121 gctagagttg ttagtgcagc aacagcgcat ccagctccat atccaattat tgatgaatgg
      181 aattatggtg taagtgataa ctatggttat tctaatgact atgttaagtc tccaaataat
      241 attggttcaa aatcttcagt aactaatcta tggggaacag ttaaggatag agattctcaa
      301 aaatatggat gggcaaactc aagcgcaaca aaaagctgga atgatgttcg attaaataca
      361 cattggaatt actttacatt ttaaaaatgg tttatgaaag ctaaaggccc aataatgcta
      421 tagggccttt tatgatatag gtaggtgctt atgaaattaa aattatgcat tgttggattc
      481 ttcttttgtt taattgctgc cattggtctg gttagtatta atgatactca aaaaccaata
      541 cctttaccaa ttgatggtgc cttctccatt caagggaaaa gcaatctttc taatgaagaa
      601 gtgtatcaaa cgattagtga cctatcaaaa gagaaaaaag ttaccattta caaaccggta
      661 gttcaaaatt cggggcagtt gacttatatc aagtttgata atactaatca tgaacaatta
      721 aagtctgcac caatcacagg gatgtattat accctaggga aattagattc aaatagttta
      781 aaaccgctca catctacagg tcttcaagtc atatatctgg cttacccttg gcagataggg
      841 ggaatgatac aatttactgg tccgttgaga ttattgctaa tgatttcaat ttacttaacc
      901 ttattagttg ttctatttgt tgttagagcg agacagatta aagaaggagt gataagacgt
      961 tctttaggat tacctgtaca cgacctaaga agagattatt tcatgtcatt tacttttgaa
     1021 ctggttatgg ccgctttatt gatgatttct tatagttctt ttttgggtag tggttttttc
     1081 acctacagtt ccaagttatt tttttctatg cttttaacta atttgatcat atttcaaatc
     1141 attgacatca tcacctttgt tctattttgg ctaactatta aggttgaaaa acctattgaa
     1201 attataaaaa ataaggccaa aaatagcctc atttttatcg tatggcttgc ggttatttct
     1261 atcataatag ttgtttcagg agtcttttta cgggaaacaa aggctagtca atcaaagata
     1321 aacatgcaga taaagcattt aaaaccatgg agtgcagtaa aagattggaa aagaccagag
     1381 tttttgggta ttgaaaatga atctgttact aatggagaag aagcaaatga ctcaggagct
     1441 aagtacgtag agattgctaa agccttaaaa aaactggatt ttatatatat caaatcatct
     1501 tcagcctatg ttccagaata tatggcagct tctgatgtta cagaagattt ttctaagcaa
     1561 ttaaaaagtg atggaataac gcatccagaa gttaataagg aactggttta tattaatcaa
     1621 acaggtgcta aggtacaaaa taaagttaat ggaacgaact atcaatcatt agataataaa
     1681 atagcaacca tctatattcc tcataaattt aaagagaata aggcatcaat cgagaataca
     1741 gttgtagcag aacaatttac tggtacaaac tatacaaaag atgaccttac ggtgcaagtc
     1801 attcctgatg ggcaagaatt tttctatttc aatgaaaatg gtagtagtgt tcctgaaaat
     1861 aaagataatc tacctttgga aagtgtgaca gatagtaagg ataatatagt cgttgtgcta
     1921 gatactgata aaatgataga aaataacgat tttattttgg caagtaatat aatatataac
     1981 tcacttttta gttcggaagc aattaagaaa atcaacgatt tgagtgctag tttgaatttt
     2041 tcaatcaatc cagtcgaggt ttaccaaact gtaaaactta atattcaatc cttagagcat
     2101 caaattttcc tttcaaaaat actgcaaata attatttgtg gaatcgtatt tctactcatt
     2161 tatcagtatg ctcaaatgtt tgttgcctta aaacagaatg actatgttaa aaaaatcatt
     2221 ttaggcctat cgaaaacacg tatagccatt tcaagtctca actattttat tgtgactatt
     2281 acaatggtta ttctattgac atttatgttg acaggacaag tagagctatt atatattggc
     2341 attgcttctt taatggtttt aattttttca acaataatga gttttagaaa attatctgaa
     2401 aaatatacac aaattctaaa aggagatgac taatggcaat tgaagttttg aatgttacca
     2461 aaaaattcgg ctcaaaaaag atattcacag atttaaattt aacgtttgaa gctggaaaaa
     2521 gctacgcatt gattggaggc tctggttcag gtaaaagtac actacttaat atcataggaa
     2581 gactagaaaa aattgacagt ggaaaggttt tagttgatga gcaggatatt tggaagacaa
     2641 aagaaagaac tttctttaaa actattattg ggtatgtatt ccagaattat tctttaatag
     2701 aaaacaaaac agtatatgat aatttgagac tcatcaataa agataaaaaa ataatagctg
     2761 atgtacttga aaaagtagga ctttctaatg actatttaaa tcagaaaata tatgaattat
     2821 ctggaggaca ggttcagcgt gtagctattg caagaatgtt aatgaagcca cgtaaaatta
     2881 ttttagcgga tgaacctaca ggagctttgg atagtgagat tggaaaagaa atcattaatt
     2941 tattattgag tgaaacagcc gaaaataaat atgttattat agcaacacat gatccagctg
     3001 tatataataa ggttgatgtt atcattgatt tgaaagatat agggagtgag atatgaaaaa
     3061 gaaagcttat atgacgttga tattattaat tggaatactc gcaattttct tagtgggaaa
     3121 acaagtaata aaaaaagaaa atcccaataa acctacggta gatttaacag tctatacgat
     3181 ctcttctagt gatacccaaa aatggaataa agtaagacaa ttagaaacag aagaagccat
     3241 atacctaata agggtaaaag aagcagcatc ttcagaagaa atattttcaa acatcattgc
     3301 agacggagct gctatgggtt ttggagttag tgaagaagat gttaaacaat tcaacaatca
     3361 tttagagaat actatagaag attctaagaa taacaaatta atcgaaatgg aattttttga
     3421 tttttctaac aataacaagg ggtttgtggt agcaaatttt gattacggta aaaaagagtt
     3481 taatgctcag aaaaaagaaa agaaagcgtt atataaaaaa ctatatgaag cttttaagga
     3541 gaaaaatcat cagtctagat agattcatta ctcaactctt tagtaacaag aaaacttagt
     3601 gacgggcttc aattaagaat tatggcaaat aagcgttgag agtatggaga taaagaagtt
     3661 tagcctttaa aaacggagct cagattgact gttaaaacaa gggtatgtca gatggcacgc
     3721 ccttttttgg tctacctgtg gtataacgaa aggagttata ctgggatttg agttgcacac
     3781 cccactcggg ttttgcactc ccttgaaagt gaaatggtta gattgtatgt taaagttaat
     3841 tgcaacagaa attggaataa ggaaattgat acaatagaac ataaagaaag ccttggaata
     3901 agggctcaat aatctccaca gtggagttac ccactacaga aattataaag ccttaaaaca
     3961 aggacgtgtt aggacaggca cgcccttttt gtttagatat ggtataatgg aaaaagagat
     4021 ttttgggaga gctgaatagc tgaatcagta tctccctaaa aaggaaatgg ttaaattgta
     4081 tggttaaatt gatagcaaca gatatggacg gaaccttttt aagagaggac ggaacttatg
     4141 acaaggagcg cttggcagct ctgttgccta agctaagaga aaaagggatt ctctttacag
     4201 tttctagtgg gcgttcgctt ttagccattg atcacttgtt tgagcctttt ttagatgaca
     4261 ttgccattat cgctgagaat gggtctgtgg tgcaatacaa gagggacatt ctttttgctg
     4321 atgtcatgac caagcagcag tgtcatgaca ttgtagagaa aattcttgcc aatccttatt
     4381 acaatcagtc tgggatcctc ttttcagggc aaaaggcagc ctatgtgctc aaaggagcta
     4441 cggaggatta tatccaaaaa atgcattatt attatgaaaa tgttcagctt attgattgtc
     4501 tgcaggatat tgttgatgac actgttttta aagcctcaac gacctttaca ggagaaacag
     4561 tcttagctgg cagtgactgg ctaaatcagg agctgtccta tgcttctgcg gtgacgactg
     4621 gctttgattc gattgatatt atcctaaaag aggttcataa gggctttggc atggatcagc
     4681 tgtgtcagca cctaggcatt ttaccggaaa agaccattgc ctttggcgat aatctaaatg
     4741 attatcaaat gctgtccttt gcagggcagg ctattgctac tgaaaatgca aggcctgaaa
     4801 tcaaagcgat ttctgatcag gttattggtc attgtaatga ctcagcagtg ttaacttatt
     4861 tggagggatt ggtgtaaatg acgcgtataa agcttttagc tctagattta gatgggactc
     4921 tctataatac cgaaaaaatc gttagtgatg agaacaaaaa agctctagca gcagctaagg
     4981 aaaaaggagt taaggttgtt atcacaaccg gacgtcctct taaggctatc ggaaatttgc
     5041 ttgaggagct ggatttgcta ggtgaagaga actatagcat tacctttaat ggcggtctgg
     5101 ttcaacgaaa tactggtcat attttagata aaagcgctct aagccttgct gaggtttatg
     5161 acattcatca gcagttggca gcggttggct tacctactga tgttatcagt gatggtactg
     5221 tttatagtct atcaggcaat gatggcagac gctctcagta tcacttggca agtcccttgc
     5281 tgaactttgt tagccttaaa tcatttgctg agctgccaaa ggacatcaca tacaataaaa
     5341 ttgttacggt gacggatcca aaggtcttgg atcagcagct tgcaaggctt ccaaagacta
     5401 tctttgagga ttttgaggcc tttaaatcac gagacatcat ctttgagatt atgcctaagg
     5461 ggattcataa ggcatttggt ttggacctgc tttgtcagca cttgggcttg gaggccaagc
     5521 atgtcatggc gatgggagat gaggccaatg actttagcat gctacaatgg gcaggtcttg
     5581 gtgtggctat ggccaatgcg gttgatcagg ctaaggaagt ggcagatgca gtgactaccc
     5641 taaccaatga ccaatcaggt gtggctgagg ctatttggaa atatatttta aatgaggaag
     5701 gctaatggga ttatttgaac gcttatttgg aaaaaaggat aagactaagg ttgctgagca
     5761 agaggctgcc actacagagg tattgtcgga ggacataacg tcaaaggata cgattgagtc
     5821 tgaaaaggag gccttatcag atacaaatgc tcatgcagtg gcagctgatg tggtctctag
     5881 gaccgatgac actagcaaac aggctgagct ctcagacgag gctgcttcag agcaagctga
     5941 agggcttgat ccagcagcta gaggagcttt tcttttagaa agagagccgg agctagagtt
     6001 agcagctact gatgacaaga ccttggatca ggcaggtgag agcctaagcc agcacgaggc
     6061 tatggaggag gctaagcatg atagggctaa gtcagagcat agtaacgaga gcgcagacgc
     6121 atcaacagaa gatcaggcag agacaaatgc tgagtatcaa gtagcagctc aagcacctgc
     6181 tggttcagct gatcagccag ctgaggaagg ccaaaagcaa gagaccctat cagctgaatc
     6241 tgatcaggaa aaatacaagc gcagcttaaa gaaaacccgt acaggctttt cagcacgctt
     6301 gaacagcttc tttgctaact ttagacgtgt tgacgaggac ttctttgagg acttagagga
     6361 gcttttgatt ctctcagatg ttggtgttca tgttgccaca accttgactg aagaattgcg
     6421 ctatgaggct aagcttgaaa atgctaaaaa gccagaggct ctaaagcgtc ttatcattga
     6481 taagctagtg gctatttatg agggggatgg ccgctacaat gaagcgattc attatcagcc
     6541 tggcttgacc gttatgctct ttgttggggt gaatggcgtt ggtaagacaa catcaattgg
     6601 aaagctagct tatcggtata agcaagaggg aaaaaaggtt atgcttgttg cagctgatac
     6661 cttccgagca ggcgcggttg cccagctggt tgaatgggga cgacgggttg atgtgccggt
     6721 cattacaggc cctgaaaaag cagatccggc ctctgtggtc tttgatggcg ttgagagggc
     6781 tgttgctgaa agggcagata ttctcctgat tgataccgca ggccgcctgc aaaataagga
     6841 caacctaatg gcagagcttg aaaaaatagg acgaatcatt aagcgtgtca tacctgatgc
     6901 cccacacgaa accctgctag cgctcgatgc ctcaacgggg caaaatgctc tgagtcaggc
     6961 taaggagttt tcaaaaatca caccgctcac aggcttgatt ttaactaaga ttgacggtac
     7021 agctaagggg ggaattgtcc tagctattcg tcaggaattg gatatcccag tgaagctgat
     7081 tggctttggt gaggctattg atgatatcgg tgaatttcac tctgaggact ttatgaaggg
     7141 actattagaa ggcatacttt aagaggaaag cctcagatta tcggctgttg gccaaagaga
     7201 atgagggggt tcgtttagag gcaaatgtca aacagccttt tgaaaacgct tgacaggacc
     7261 tttaggagat gataaaatga aaacgttatt agatgtgatt acttagggta agcgtgctaa
     7321 tgacaaatga atcagaatat taaaggatgt tatcacagtt ttgtgagcag ggacctattc
     7381 cagtgtggcc ttttagcatg ctgtggatag gtcatttttt attgtgaagc aatgagggac
     7441 taggactttt atgattatta aacgcgtttt aaaccataat gcagcgattt cgaccaacca
     7501 tcaggggcta gatattcttt tgatgggaaa ggggattgct tttaagaaaa gaattggtga
     7561 ccatatcgat agtgaagcta tcgaagcgtc atttgtttta aaaaatagtg acaatatgaa
     7621 ccgttttact gaattattta ttgctgttcc gcaagaggtg gttgcttgct cagagaggct
     7681 tattaatcta gggaaaatta agctgggtaa aaatttagat gaaatactct atatcaattt
     7741 gacagaccat attcattcag ctattgaaag acataagcag gggatgatca ttagtgatcc
     7801 cttgcgctgg gagattagac ggtattatcc tgatgaatat gcgattggcg ttaaggcctt
     7861 agaggtcatt gccagtgagc taggagtcgc tctggctgta gatgaagctt cgtttattgc
     7921 gatgcacttt gtcaacgcga gccttgataa tcctttcaag gagcctcatc gaatgacaga
     7981 aattgtgtct tacattgaac agaaggtcaa ggctgatttt aagacagagc ttgatgaagt
     8041 ctctattgat tattatcgct ttatcactca tgtgaagcta tttgctcagc gcgtgttatc
     8101 aggcatggct tatgatgatg acgagactga tttgctgctg atggttaagg ataaataccc
     8161 agaggaatat cactgtgtta ggcaaattag ccatcacatg aaaaaagcat accattatca
     8221 gcttagctct agtgagcttt tgtatttaac ggttcatatc aaacgtttag tcaaaaatgt
     8281 gaaggagtaa tgaaatgact tatcaagaaa cagccaaggc catttttgaa gcagttggtg
     8341 gtgagcagaa tattcaagag gtaacccact gcatcacgcg gttacgcttg gttttgaaag
     8401 atgataaaca agtggtagat caaaaaatca aacttattcc taatgtgatt ggagtcatgc
     8461 gccaaaacgg tcagtatcaa attattttag gaaacgatgt taacaattat tataaggcat
     8521 ttatgaccct aggacagttt catgaaactg atatgagctc tagcgctggt caaaagcagt
     8581 ctatgattga agggttgatt gaaacgatag ctagtgtgat tactccactg atacctgcct
     8641 tactgggagg cggtatgtta aaggtggttg ggatcttggt gcctatgctt ggtctagcag
     8701 gtacggactc tcaaacagtt gcttttatta atttttttgg agatgctgct tattatttta
     8761 tgccaatcat gattgcatat tcagctgcgg cacgctttaa ggtcacacct gtattagcag
     8821 caactgttgc agggatttta ctacacccag cttttgttac gatggtagct acaggtaaac
     8881 ctatggcttt gtttggagcg ccggtgacac ctgctagcta tggtgcgtca gttattccga
     8941 ttttaattat ggtttacctg atgcaataca ttgagcgaga ggttaaccgt tttgtaccga
     9001 gtgtgatgaa gagcttcctg cagccgacct tgattatttt tatttcaggc tttctagcct
     9061 tagttgttat tggacctctg ggtgttatta taggacaggg cttgtctaat agcctgctag
     9121 cgatttacca tattgctcct tggctggctc ttgctatttt aggtgcaatt atgccgcttg
     9181 ttgttatgac gggtatgcat tgggcctttg ctcctatttt tctggcggcc tctgtagcaa
     9241 ctccagatgt tttaatcctc ccagcaatgc tagcctctaa cctagctcag ggatcagcag
     9301 cggtggctgt agcatgtcaa tcaaagcaaa agcaaacccg tcaggttgcc ttagcagcag
     9361 gcttatcagc tttattggca ggaattacag agcctgctct ttatggcatt actctaaagt
     9421 ttaaaaagcc gctctatgct gcaatgattt ctggtggcct tgtgggcgcc tatattggct
     9481 ttgttaatat agcctcttat acttttgtgg tgccatcact aattggattg ccacaataca
     9541 ttagcccgac tagctctgct aattttacca atgccttaat tgcagcgggc ttaacaattg
     9601 ctctaacctt tacattaacc tggttttttg gcattgatga ggaggttgac caggaggggt
     9661 cagctgactc ggatagcacg ccagtaaaaa gtggcttatc agcaaagcaa tctatttatg
     9721 ctccgatggt tggcacagtg cttccattat cagaggtgcc agatgaaacc ttttcgtcta
     9781 agcttttagg agaggggctg gctattttac ctaatgagga atatgtctat gccccatttg
     9841 atggcgaggt tatcaccctt tttccaacaa agcatgctat tgctttaaag aacgccaagg
     9901 gagttgacgt cttaattcat gttggtattg atacggttga gctaaaagga cagggctttg
     9961 agcagctggt taaggctggt gatactgtta agcaggggca gccgctgcta cgtatagatc
    10021 ttgaattgat tggctctaag ggctattctt tagtgactcc atttgtggtg accaatagct
    10081 ctgagcagct cgaaatcatt gttaatgaca acaaggagca tatcactcag catgatgttg
    10141 ctctcgttat tctctaaaga gatgaattga aggaggagat aatatggttt gttttccaaa
    10201 ggatttcttg tggggagggg cagttgctgc caatcaggtt gagggagctt atttaacaga
    10261 tggcaaaggc ttgtcggttc aggatgtttt accagaaggg ggcttaggag actatacagc
    10321 tgagccaaca gcagctaatt tgaagctaga ggccatcgat ttttatcacc gctacaagga
    10381 ggacgtggcg ctctttgcag aaatgggctt taaggttttc cggacatcaa ttgcttggtc
    10441 tcgtattttt cctcagggcg atgagacaga gcctaacgaa gcagggctac aattttatga
    10501 cgatttgttt gatgagctga tagcacatgg catagagcct ttagtgaccc tatctcacta
    10561 cgaaacccca ctgcatctag ctaaggtcta taatggctgg actgaccgtc gtatggttgg
    10621 cttctttgaa cgttttgcga caactgtcat gcagcgctac aagaacaagg ttaagtattg
    10681 gttaaccttc aatgaggtta attcaatcct gcatatgcct tttaccagtg gtgctatcat
    10741 gacaccaaag gaaaagctga ctccgcagga gctttatcaa gcgattcacc atgaattagt
    10801 agcgtctgct agtgtgacaa ggcttgctag attgattaac cctgctttta aaataggctg
    10861 tatgattttg gctatgccag cctatccaat gacctctgat ccgagggata ttttagctgc
    10921 gaagcagttt gagcaacgta atctcctgtt ctcagatatt caggtcagag gaaaataccc
    10981 ttcctatgcc aaatcctttt ttaaggagca gcacattgac attcaatttg aaccgggcga
    11041 cagtgagctt ttggcgcagc atacggttga ctttttatcc tttagctatt acatgagtgt
    11101 gactcagtct catcacccgg atcattatca acgaggggag ggcaatattt taggtggctt
    11161 ggttaatcct catctgccct cttcggaatg gggctggcaa attgatccaa ttggccttcg
    11221 cataaccttg aatgattact atgataggta ccaaattcct ctctttattg tagaaaatgg
    11281 gcttggcgcc aaagataagc tagtacagac aaaggatggt cactggacag ttcaggacga
    11341 ttatcggatt gattacatga ggcagcattt attgcaggtt gctaaggcta ttgaggacgg
    11401 tgttgacatt atgggctata cctcctgggg ctgtattgat tgtgtttcta tgtcgactgc
    11461 tcagctaagt aagcgttatg gctttattta tgtcgaccga catgatgatg gcagtggtca
    11521 tttgacacgc tacaagaaaa aatcctttgc ttggtatcaa agggtcattg agaccaatgg
    11581 gcgtagcctg tctgaggaga gctagaaagt agcctcaaag gctttaccaa caatagcaaa
    11641 gccgtatagc acacgtcttt taaaaggctg atgctatacg gcttttagcc atttcattta
    11701 aatggaacga actcaattac gtctttgtac tgtcccctaa caaaaagcct ccatagacct
    11761 gtgtcatagg tgtggaggct taatgcttgt taaaataccc tatagacata agggttatca
    11821 ggctctgggg cttggtgtgc ttcctcgatt tgaaggacag gaagctgctg ctctagggtc
    11881 ttgtcatatt ccatgtgcag ctggcccttg acggtcagcc aagtgttatt ggcatagctt
    11941 tcttgattac cagtggtcag aagcccatac acaccggaat cagcgataca atggataatc
    12001 ccaaatctaa agaggaattg atagctgtca tgtcctggct cattatagac aaagccagtg
    12061 tactgaatcg tacgatcaac gaattcgtct gggtaaaggt agattaattc cattacctcc
    12121 atataattgt cagtggtaat ggtgatggct gatttgcctt ggtatttttt cagttcattg
    12181 agcatttcct tttgataggc ggatttggta aagtacaggc tggtgtctgg ctttaggtat
    12241 tgaatagtag taccatcatc actgacccct gtttttgaag cgcctgcggc taatggaaag
    12301 gtatagccct tggcggcaac ggtcgtcgaa tccaagctga ctgtaggtac taacaagcca
    12361 accaaaacag gaaagaccag gataagggga ctggtcagct gagcgacctt accttttaaa
    12421 tgactgtgta gcttgatgtt tttagtccaa gtgtatagct gcaccaatgc aaggataaag
    12481 gatagaacca tagaaatata ggctaagtaa gcgtaacgaa tattgatata ttgatttagc
    12541 ttgccagata gctctagata catggtcaac tcaaaatagc ctgctaaaat taaaaagcga
    12601 atcatcacag cacccccaca agtaagcaat atatggtaat catcacagct gatacactga
    12661 taaattgaac aataaaggct cccttaaagg aattgagcat catcatgagg tttttgatgt
    12721 caaccatagg gccgattaag agaaaggcta aaacaggagc aactccaaag gttgacaata
    12781 acgaagctcc aataaaggcg tcagcctcac tgcaaagaga taagataaag gctaagagca
    12841 tcatgactaa gatggctgtc aaagggctat gtccgatcgc tgtcagcacc tttgttggca
    12901 gataaatctg catggctgaa gcaatcaggg tcccaaagac tagatacctt cctgtatcaa
    12961 aaaattcgtc aatagcgtga gccagtgcca agtaaagccg ttttggcagg ctttcgtgac
    13021 tgtaagtatg acaatgcacc ggctgggttg attccttgag aatgttctca tcaacaatga
    13081 aggctagcat gatgccaagg ctgacagcca ctaaaatggc gcctaaaagc cttagcatga
    13141 gaaagcgcag cgaattccca aaggcagagt aggtagcaaa taaaacaatc ggattaataa
    13201 ttggagcggt tgctaaaaag ggaacagcag tgtagctagg caccttcttt tctaaaaaac
    13261 gattaataat aggaatgata ccacattcac aggaaggaaa aacaaagcca ataaaggtac
    13321 caaataaaat tcttagccac ttattttgag ggaggtatct ttgaactaaa tcaggcgtga
    13381 cgaaaacctc aatacagcca gataaaatag tccctaaaaa tacaaaaggc agggcttcaa
    13441 tgataatgga tagaaaaatc gcaaaccatt gaagcacgct gggtggcaga tttgaaaaaa
    13501 gcgacattca ccgtatcctt tctatatgtt aacgacgcca ataagggcta gtcctgctta
    13561 gctgtcttga cttgtggctt tggtttttca gtgactagct ttccatcttg gttaagctct
    13621 aaaggcttat caaaatctgg gatagacgca aagcctgcca tcatcttttc gagctggtca
    13681 tttttcttat gagtaattgc cataggtata ccttctttca atcaatatag ctctattata
    13741 caatcatttg acggtaaagc caaagctaaa acatcttttt atcttctgat tgattttagg
    13801 cttcaggccg tcaagcagtg tgtcattaga ttgactgaca aatatgatat aatgtggctg
    13861 atgggagcta tgaaatgaca aaacgagtat tattagtaga tgatgaggag cctatcttaa
    13921 ggctactgga ttatcacttg gccaaggagg gctttgtgac agagatggta acagatggcc
    13981 gtactgcctt ggcattagct gaaagagaac cttatgattt tattgtgtta gatattatgc
    14041 tgccgcaatt agacggtatc gaggtctgca aaaggcttcg tgctaaggga agcaaaaccc
    14101 caattatgat ggtttctgct aaaagtgatg aatttgacaa ggttttggct ttggagctgg
    14161 gggcagatga ttatgtgacc aagcccttta gtcctagaga attattagcg cgtgtcaagg
    14221 ctattttaag gcgtactgaa gcagagattt ctggtgatgg tgaagagcgt cgtgagcctt
    14281 tttatacgat gagtcaattg cgtctgtacc cagagcgaca tgaggtctat aaggacaagg
    14341 agctattgcc gttaacccca aaggaatatg agctactgct ctatctcatg aagcacccta
    14401 atatgaccct gacgcgtgag cggctattag agcgtatctg gggttatgac tttggccaag
    14461 aaacacgtct ggtagacgtt catattggca agctcagaga aaaaatcgag gacaatccta
    14521 aggcgcctca gtatattcaa accattcgcg gctatggcta caaatttaag gagctaaaga
    14581 atgataggac atcttaggcg tttgagcatg ctgctagggc tttgcttgct ggctgctctt
    14641 ggtctgattt ggcaagggcc gcatcaggtg ctgactctag tagtgctgtg tactggtctc
    14701 gtagctagct tttatgtctt gagcatgcta tttagatggg agcgtgaatt cagagccttg
    14761 caccaccatc ttttgacagc tagtgaccat tttctcctag tggggcaggc tgatttaagt
    14821 gcttatgcta agcagctgac agagctaaaa agtgacctat tacaaaagga agcaaggcta
    14881 aaagccttat caaaaaatgt ggaggctgta acctctcatc tcacgatggg catgctttta
    14941 gtctccaatc aaagggagct gttgctgacc agcaaatcct taccggctta ttttccagag
    15001 gctaagccac cttttgtggt cttggaggat cttaaacgaa tggatctgat agccttagtt
    15061 aatcaagtct ttgaccaaaa gcagacatta aagaaggaat taacaggcct acatgatggt
    15121 gatttgatct tggaggttac ccttgtgcct atctttaacc agtcgcatgt tgtcaaggag
    15181 attttagtgc tcttatatga tctgacggcc attcgtcatt atgagaggct aaatttggag
    15241 tttattgcta atgcttctca cgaattaaga acaccggtta catcgatcaa gggctttgct
    15301 gaaacgatta aggaaatgcc tgacgatgaa acaagcctaa aagaagactt tttagacatt
    15361 atctacaatg aaagcttgcg tctagaacgt attgttgagc acctgctgac cttatccaag
    15421 gctaacaaga caccacttga cctgacagag tttcagctca ggaacttcct gctgtataca
    15481 ggtcagagca tgaggccaca gctagagcaa aagcagcttg agctaagcta tgcattggag
    15541 gattcgattg ttgtgacatc tgatcaatac ctcttatcgc agatcatgtt aaatctctta
    15601 tcaaatgcga tacagtatac agacaatggg ggcagaattc agctatccag tcaaagggtt
    15661 gctggtggtg ttgccattac agttgcagat actgggattg gcattagcca aattgagcta
    15721 gatcgtattt ttgagcgctt ttatcgtgtt aacaagggac gtagcaggca aagtggtgga
    15781 acaggcctag gcctagccat tgtaaaggag ctgagtcagc ttcttggcgg tcagataaca
    15841 gtcacaagtc agctaggaga gggcagccaa tttaccttat tcttaccaga agctatcaac
    15901 aagtaaacag tcactaccag ctacttaagg ccagccttgg tagtggctgt tttaggtttt
    15961 acaaaatctt tacattaatc agggataaac ctttacaaag acctgataag ctataggtgt
    16021 agcaagccta caacacaata tcataaaaga taagggtgat tcttatgaca atcaaaaaaa
    16081 tgctgatcat ggcagctatt ggcttatcag gcttaggtct tgcagcctgt ggcaataaca
    16141 gtgctgatgc tggaaaagca gcagacagga ttgaccttgt ttctcgagaa aatggctcag
    16201 gtactcgtgg agcctttacc gaaatgacag gcattctaaa aaaggacggt gacaaagaga
    16261 ttgaccaaac agcaaaaaca gctattatcc aaaatagcac agaaggggtc atctcctctg
    16321 ttaagggaaa tagtcgtgcc attggctaca tctcgctagg gtccttaaat agcgacgttg
    16381 cagccctaaa ggtaaatggc gtaaaggcta gtcgtgagac tattttagag gggaaatacc
    16441 ctctgcagcg tccctttaat attgtatggt cctcagacct atcaggagtt ggtaaggatt
    16501 ttatcacctt tattgactca aagcaggggc aggagattgt tagagacaat cgattgatcg
    16561 aagcaaaaac agacgcgcca gcctatagca gtaagggctt atcaggcaag ctgtcaattg
    16621 taggctcaac ctcagtttca cccttgatgg aaaaattagc agaagcatac aagaaagaaa
    16681 atccagccat tagcattgat attacctcaa atggctcatc agcaggtatc accgccgtca
    16741 aggaaaaaac agcagacatc ggtatggttt ctcgtgacct aacaactgag gagagcaagg
    16801 gcttaattga tgatgcgatt gcccttgatg gtatcgtagt gattgttcac aaggacaata
    16861 aggtaagtaa tattggcata gatgtgctgg ctgatgtctt tagcggcaag ctaacaagct
    16921 gggacaaagt caaataaaga acgattagaa ggaaggcaaa gaagaggtgt tttgttcttg
    16981 ctttcctttc ttagaaagga tcatcagtga ataaacaagc ctttaaagag gattttttta
    17041 aagttatctt ctttctcagt gcagcgatgg caattattgc tatttgttta atctgtatct
    17101 ttatttttag taatggcctt ccctttattg ctaagtatgg tatgagagcc tttttgctag
    17161 gaaatgattg gtcaccgtca aatcagccgg caagctatgg tattttgccg atgattgcag
    17221 ggtcttttgt catcacactt ggtgcaatgg tgattggtgt gccaacaggt atattgacct
    17281 cagtttttat ggtttactat tgtcctaaag catgctatgg ctttttaaag tcagctgtta
    17341 atctgatggc agccattccg tctatcgttt atggcttttt tggtcttcaa gtgctagtgc
    17401 cttggattag gagctttgct ggtaatggca tgagtgtgct gactgcctcc ttgctcttag
    17461 gaatcatgat tttgccaacg cttatcagtc tttcagagtc tgctatcaga gctgttccaa
    17521 aggcttatta ttcagctagt cttgcactgg gagccagtca tgaaaggagt atttttcgag
    17581 tgatcctgcc agcagccaaa tccggccttt tttccgctct tattttagga tttggtcgtg
    17641 ccattggtga gacgatggca gttattttgg tagcaggaaa ccagcctgtg ctgccatcag
    17701 gattatttga gggcacaaga accatgacga caaatattgt cctagagatg gcatatgctt
    17761 ctggtcagca tagagaggcc ttgattgcaa catcggctgt cctctttggc tttattctca
    17821 tcattaatgc ttgctttgct tatgtgaaag gaaaatcagc tcatgactaa ctatttacta
    17881 aaagccctgg tctatctttt gtcgctattg acctttggct ccttattttt gattattgcc
    17941 tttatgctga taaaaggctt gcctagtctg tcgttatcct tattttcatg gacctatacc
    18001 tctgacaatg tttctctaat gccgtcgatt atctcaactg ttagtctagt tttaggcacc
    18061 ttagtgctag ccttgcccat tggtgtcttt gctggcttct atcttgtgga atacgctaag
    18121 caggactcac tatgggtaag ggcaatacgt cttgcagctg atacgctatc agggattcct
    18181 tcgattgttt ttggtctttt tggcatgctg ttctttgtgg tttttttcgg cctgcaatat
    18241 tctcttttat caggtattct gacgtctgta atcatggtgt tgccagttat cattcgatca
    18301 acagaagaag cgctcctctc tgttagtgat cacttgcgtc aggctagcct tggcttagga
    18361 gcaggtaagc taaggacgat ttttaaaata gtgctgccgg ctgcaatgcc tggtattcta
    18421 gccggggtaa tcctagcgat tggacgtgtt gtgggtgaga cagcagccct gatgtatacc
    18481 ctaggcacct ctaccaatac gccaaccagc ctcatgtcat caggacgctc actagctctt
    18541 cacatgtaca tgctgtctag cgaagggcta catgtcaagg aagcttatgc aacgggtgtt
    18601 atcttactca taactgtctt gctgatcaat gccctatcaa gcttattatc acgccgatta
    18661 gtgaaaggag tcgtctaaaa tgggagcttt ttcaaccaag cagcttaatg tcttttatgg
    18721 agcatttcag gccttaaagg atatctccat tgacatacca gaaaatcaga tcacagccct
    18781 gataggtccc tctggctgtg gcaaatcaac ctttttaaaa accctaaatc gcatgaatga
    18841 cttgattcct tcctgtcgta tcgaaggaga ggttctctta gacaatcaag acatctatgc
    18901 taaagcaata aacctcaaca gtctgcgtaa gcgtgttggt atggtctttc agcagcccaa
    18961 cccatttgcc atgtctattt atgataatgt ggcttatggt cctaggacac atggccttaa
    19021 ggacaagaaa actctagatc agctggtaga gcagtccttg agaggagcag ccatttggga
    19081 cgaggtcaaa gacagcttaa aaaagagtgc catgtcccta tcaggtggac agcagcagcg
    19141 gctttgcatt gcaagagcgc ttgctgtagc acctgatgtg ttgctcatgg acgagcctac
    19201 ctctgctctt gatcccattt ctaccttaaa aattgaggac ttggttcagc aattaaagca
    19261 ggattacacg attatcatcg ttacccacaa catgcagcag gcttcacgca tgtcagataa
    19321 aacagccttt ttcctcacag gagatatttg tgaatttggc gatacagctg aactatttac
    19381 aaagccaaag gacaagcgta cagaggatta tatttccgga cgcttcggat aagaaaagga
    19441 ctaggcgatg aaagagcaat tggaatgagg gctaaatctc tcctcaattg gtgttttgat
    19501 gatgtcagat cagtatccta ttagcgtgga agcttctctc ttacttcctg tagagtgaag
    19561 cttttttgct ttctttgata agcacgatct agctattttc agacaaaggt tactggtatt
    19621 agaaatatat atatatatat attagtaaac tataatctta ttaatattat ataataacta
    19681 cataaaaaaa caaataggag tcatatcatg aaaaaattac tattaactag tgctgcagcg
    19741 ctagccttag caacagtagc agttagcaca acaaaagtag aggcgttttc tcgtgggcat
    19801 gttatagagc atacgattaa cgacaccaag tcgcttagtg cagcgcgctg ggggtcaaga
    19861 ctgcaaatcc ttaatctgtt aacacgattt aagcataaac taggagagga tggctttagg
    19921 tcttataaca gacaattcag agctagggta ggtgcagcaa aatcagtaag tgaaattgat
    19981 gaactttata ataagtttga aaaggagttg gaagagttag aagatctcac ttaattttga
    20041 ctaaccacta agtagctaaa agacgatttc cgtttggaga tcgttttttc ttagccttta
    20101 gaagtatctg aaaagataag ttttgttttc ttgacactta tttgtcataa agcttttatc
    20161 ttgttctatc cctctttctt tgtgctataa taagaactgt tatggaaaat atgaatcatc
    20221 aaaacatttc agaagcgttg ggggtcaccc caaaacagat tagtcaagtg cttaccctta
    20281 ccgctgaggg taataccatt ccctttattg cgcgctatcg taaggaagct acaggtaacc
    20341 ttgatgaagt ggtgatcaag gccattattg atatggataa gtccctcaca cagcttaggg
    20401 agcgtaaaga caccattctt gctaaaatcg aaggacaagg gaaactaaca gctgccctta
    20461 aggaagctat agaagcagct gataaattgg ctgacctaga ggagctttat ttgccttaca
    20521 aggaaaagcg gcgtaccaag gcaaccattg ctcgagaagc cggcttatct ggactagcta
    20581 gactgatcct tcaaaatgca caagacctag aaactaaggc agaggccttt atcacagaag
    20641 gtttttcgga tccacaggca gcccttgctg gagctgttga tattttggtc gaagccatgt
    20701 cagaggatag caggctaagg tcctggacct ataatgagat ttggaagtat agccgtataa
    20761 cctctagcct aaaggaagcc agcttagatg acaagcaggt ctttcagatt tactatgcgt
    20821 tttctgagac ggtatctaac atgcagggct acaggaccct agctctcaat cgtggggaaa
    20881 agctaggcgt attaaaggta tcctttgagc atcatataga caaaatgctg cgctttttca
    20941 gccttcgctt taaggagcac aatgcttata ttgatgatgt tattaaccaa acaatcaaga
    21001 aaaaaattgt tcctgctatg gaacgacgta tccgcacaga attaactgaa atggctgagg
    21061 acggtgctat caagctcttt tcggaaaatt tgcgtcatct tttgctaatt tcaccactaa
    21121 agggaaaaat ggtgctgggc tttgacccgg cctttaggac aggggccaaa ttagcggtga
    21181 ttgatccgac tggaaagctg ttaactactc aggttatcta tccggtggca ccagctaatc
    21241 aagctaagat tcaagcagca agagtagctc tagctcagct catcactgac tatcagattg
    21301 atattattgc cattggtaat ggcacagcca gtcgtgagag tgaagccttt gttgcagagg
    21361 tgctaaagga ttttccagaa acctcttatg tcattgttaa tgaaagcgga gcttcggttt
    21421 attcggcctc agagctagcc cgccatgaat ttccagagct gacggttgaa aagcgctcag
    21481 ccatctctat tgcgcgtcgc ttgcaagacc cgctagcaga gctggtcaaa attgacccaa
    21541 aagcaatcgg tgtcggacaa taccagcatg atgttagtca gaaaaagcta tctgagcatc
    21601 tggattttgt cgttgatacc gttgttaatc aggttggggt taacatcaat acagctagtc
    21661 cagccctact ggctcatgtt tcagggctaa ataaaaccat ttctgagaat atcgtcaggt
    21721 atcgtgaaga aaatggagag atcacctcac gtgctgagat caaaaaggtc cctagactag
    21781 gcgcaaaggc ctttgagcag gcagcaggct tcttgcgtat tcccaatgct aagaatatat
    21841 tagacaatac aggcgttcac ccagaagcct atccggctgt caaaaagctc tttcaattac
    21901 ttgcgattaa agacttagat gagcctgcaa gggccaaatt acaggcggtt aatcttgagg
    21961 aaatggcaga gcaattgacg cttggtcaag aaacgctcaa ggatatcatt gctgatttgc
    22021 tgaagccagg aagagacttg cgtgatgact ttgaagctcc tgttcttcga aaggacattt
    22081 tgagtgtaaa ggatctggct gttggtcaaa ggctagaggg aactgttaga aatgtggttg
    22141 acttcggtgc ttttgttgat attggtgtac atgaggacgg tttgattcac atttcagaga
    22201 tgagtgaggc ctttgtcaat cacccaagtc aggtcgtttc tgtcggagat ttagtcactg
    22261 tttgggtttc taaggttgac ttagaccgcc acaaggtcaa cctaagctta gtgccgcctc
    22321 gtgagtctga ctgattatgt tagagaggtc tcgctagctg attttggaaa gccctttaag
    22381 catcaggctt cttggaacag acgactaaga acaacaggcg gacgtttttt tccaaaggat
    22441 ggtcatctgg atttcaatcc caaaatctta gaggagcatg gggagactgt ctttagacag
    22501 atcgttaggc atgagctttg tcattatcac ctctattttg aggggctggg ctttcggcat
    22561 aaggatcaag cctttaagga gcttctagac caagtagacg gtctgagata cgctccaaaa
    22621 ttacagtcac atcaagctaa ttacctctac atctgtcaag attgcggcca agcttatgac
    22681 cgaaaacgtc ctatcaatct ggcggtattt gcctgcggca ggtgtcatgg caggctcatt
    22741 gaaaaaaatc agtcgtaagg ctgattttat tttgctaaaa aaggaataaa ctagtatcat
    22801 agaataagga ggcgaggaga catggaatct aaattttata agcaacgaaa gcataagcta
    22861 gtggctggag ttatctctgg tttagctgat aaatacggct gggatttgcc cctagctcgt
    22921 gtgcttgccg ccttattgat ctattttact cgctttgggg ttgttattta tattctttta
    22981 gccatcttcc taccatataa agaggaccta cttgaagaac gttacgggag aggaccaaga
    23041 cgtcgcaagg atgctgatgt cctaaatgat gaagatgaag gctggttttg gtaagaccac
    23101 agcgagcgac tattaaaagc ttgacaggaa ttttaatagt gcctctagcg tgattatcag
    23161 aaataaagct ggctgtaggc ctttatctga tgagataggg ccttttgttg tttgtccgct
    23221 ttaggctagt gcctgcttta agtgagcctg aggcagctgt tgcaggattc ttttttagta
    23281 tgatcaagca ctttgaaagc ttctttgaaa aataagtatt tgtaagggct tagatagtga
    23341 tttatgatat aatattaaaa aaggagaaat tatgacagtt accgttaaga tgttagtcac
    23401 aaaggtcaag cttgacgttg tctatgcaac tgatgacttg ctagaaaagg agataacgac
    23461 ctcagatatt tcgcgtccgg gtcttgagat gaccggctat tttgattact atgccccaga
    23521 gcggcttcag ctgtttggca tgaaagaatg gtcctacctc actcagatga cctcacacaa
    23581 tcgctactca gtcttaaagg aaatgtttaa aaaagacacg ccagctgtga ttgtatctag
    23641 gggcctagct atcccagagg agatggttca ggcagcgcag gaggaaggta ttgctctgtt
    23701 tagcagccgc gtatctacca gccgcttagc tggtgagatg tcttattttc ttgatgcttc
    23761 cttagcagag cgaacaagtg tgcatggggt gctgatggat atttacggta tgggggtgct
    23821 gatccaaggt gattcaggta ttggtaaaag tgagacaggc ttagagttgg tcaagcgtgg
    23881 ccatcgcttg gtggcagacg accgagtaga tgtctttgct aaagatgagg agacgctatg
    23941 gggggagcca gcagagattt tacgtcatct ccttgagatt cgtggtgttg gcattattga
    24001 tgtcatgtcg ctgtacggtg ctagtgctgt caaggattcc tcacaggtgc agttggctat
    24061 ttatttggag aattttgagg ctggcaaggt ctttgaccgc ttgggcaatg gcaatgaaga
    24121 gattaccttt tctggtgtca gtattccaag gattcgcatt cctgtcaaaa caggtcgaaa
    24181 tgtgtcagtg gttattgagg ctgctgccat gaaccatcgt gcgaaagaga tgggctttga
    24241 tgctaccaaa acctttgagg agcgccttac acgtttaatc agcaaaaatg aggagggcaa
    24301 atgatcaatc caatagcctt taagcttggt cctcttagtc ttcactggta tgcggtttgt
    24361 atcttggtgg gattactttt agcggtttat ttggcagcca aagaagcccc gcgaaaaaaa
    24421 atgaccagtg atgatattat tgattttatt ctgattgcct ttcctttggc aattattgga
    24481 gcaagaatct attatgtagc ctttgaatgg tcctattatt ctcagcattt gagtgatatc
    24541 tttgctattt ggaatggtgg gattgccatc tatggcggct tgataacagg taccattgtt
    24601 ctctttgttt attgctacta taaggtgctg aatcctatcc atttcttaga tattgcagcg
    24661 cctagtgtca tgcttgctca ggccatcggc agatggggaa atttctttaa ccaagaggcc
    24721 tatggcaggg ctgtcagcca gctcaattac ctgcctagtt ttattcgcca gcagatgttt
    24781 atagatggca gctatcgtgt tcccaccttt ttatatgagt ccatgtggaa cctgattggc
    24841 tttgtcatta tcatggtgtg gcggcgtaag cccaggtcat tagtagatgg ggatattatc
    24901 tcattttacc tgatttggta tggctgtggt cgattggtga ttgagggcat gcgaacggac
    24961 agcctgatgc ttttaggaat tcgtgtttct caatacatgt cggtgctgct cattatcatt
    25021 gcgattgttt ttatctttaa aaggcatcga caaaagggaa tttcttatta tcaagaatag
    25081 ggatagaaag aggagacgtt tatgaattta gtgggcattt cattgctgat aatcgcatta
    25141 gcctttgttg ctctggttat ttttttgatt gtggtgttaa aaaaggtgtc agaggcagtt
    25201 gatgaggcta aaaaaaccat taccgtttta acgagtgatg tcaatgttac cctttatcaa
    25261 accaatgaaa tattagctaa ggctaatgtg ctggtagatg atgtgaatgg taagatgaca
    25321 acaatagatc ctctctttgt tgctattgca gatttgtcag aaagtgtttc tgatttgaat
    25381 gtgcaggcca gacaccttgg acgtcgggcg acaaatgcca caagcaatgc tgcaaaggtg
    25441 ggtaaagtag ctcttgtcgg caaggtcgct tctaaattat ttggtaaaaa ggagaaaagg
    25501 tcatgagtaa tttttttaaa acgttggtga ttggtgtagc ttcaggagca gctaccgctt
    25561 atttcttgtc aactgaaaaa ggaaaggtct tgaaggctcg cgcacaaagg gcctatgaag
    25621 cctatcgtca aaatcctgag gaatatcatc aaatggctaa agaaaaagga agtgagtaca
    25681 gtcagctggc tcgccatacc tttaatgatt taaaaaccag gtttgaatca ggggatatga
    25741 ccactgatca ggtgtttgat tttatcaagg aaaagaccag ccaatttgtt catcaggcaa
    25801 aggaagctgc ttcagagcat gacaaggctg atgatgtgat tattgatctg gatgaagagg
    25861 atattattat caactatcct gaagatgatt cagaaaaaga agcagctagc aataagtctg
    25921 aagaataata aggcaaaaat aagggctctc tcagctatgg agggcctttt gtgatgtggg
    25981 ctactcgttt attcaagaaa ataggcaata agagtaatga aaaaagagct tagcgaagcc
    26041 aagctctaac tgtttatgac attaataacg tgatggcctt tgaaagaaag gaagtgatgg
    26101 ctaggctgat agcactagca attagaaagg cccaaaccgg tgccaaattc atgacaagaa
    26161 ggacaaatgc aaacaagaca gtgattaaac taaaaacagc aatacgggca aaaaaaataa
    26221 gttccttgag cttgctactg tgtccattga ggtcttgaaa ctcttgaaat ttttgctgcg
    26281 agacctgctc ttgcttctgc tgcttgagct gccgctgctc caatggtgta ggcatagtcc
    26341 tctcctttcc cgtaagatac ccaaccattt taccataaaa gctgatggtt gtcatctttt
    26401 ttttgaaggc ttctcgtt
//
LOCUS       DARYJX010000033        26032 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYJX010000033 DARYJX010000000
VERSION     DARYJX010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26032
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(7..369)
                     /locus_tag="TU257_001417"
     CDS             complement(7..369)
                     /locus_tag="TU257_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0834426.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TU257_001418"
     CDS             complement(347..781)
                     /locus_tag="TU257_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0834427.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TU257_001419"
     CDS             complement(768..1058)
                     /locus_tag="TU257_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0834428.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TU257_001420"
     CDS             complement(1015..1440)
                     /locus_tag="TU257_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL0834429.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TU257_001421"
     CDS             complement(1418..1741)
                     /locus_tag="TU257_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0834430.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TU257_001422"
     CDS             complement(1742..2728)
                     /locus_tag="TU257_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL0834431.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU257_001423"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU257_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL0834432.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TU257_001424"
     CDS             complement(3829..4476)
                     /locus_tag="TU257_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834433.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TU257_001425"
     CDS             complement(4478..6481)
                     /locus_tag="TU257_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL0834434.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TU257_001426"
     CDS             complement(7018..7383)
                     /locus_tag="TU257_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL0834435.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TU257_001427"
     CDS             complement(7444..8490)
                     /locus_tag="TU257_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0834436.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..9608)
                     /locus_tag="TU257_001428"
     CDS             complement(9054..9608)
                     /locus_tag="TU257_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834437.1"
                     /translation="MRLKKLIYSSIAALAILTYGTISANADASIPEIDQTEVITILKS
                     DGYLNIDEGTQEVTITEKYKQAVLSSIDLDRQEAIFTENSVTIRDIFSPRSFTGVNKI
                     VFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANA
                     AGRGVIVAFVGTFPRGVIHWVASQ"
     gene            9877..10087
                     /locus_tag="TU257_001429"
                     /pseudo
     CDS             9877..10087
                     /locus_tag="TU257_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10179..13814)
                     /gene="rpoC"
                     /locus_tag="TU257_001430"
     CDS             complement(10179..13814)
                     /gene="rpoC"
                     /locus_tag="TU257_001430"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL0834438.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(13905..17471)
                     /gene="rpoB"
                     /locus_tag="TU257_001431"
     CDS             complement(13905..17471)
                     /gene="rpoB"
                     /locus_tag="TU257_001431"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0834439.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            complement(17733..20033)
                     /locus_tag="TU257_001432"
     CDS             complement(17733..20033)
                     /locus_tag="TU257_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0834440.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            20138..21394
                     /locus_tag="TU257_001433"
     CDS             20138..21394
                     /locus_tag="TU257_001433"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL0834441.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAHEDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(21429..22238)
                     /locus_tag="TU257_001434"
     CDS             complement(21429..22238)
                     /locus_tag="TU257_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0834442.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(22231..22950)
                     /locus_tag="TU257_001435"
     CDS             complement(22231..22950)
                     /locus_tag="TU257_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0834443.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(22953..23396)
                     /locus_tag="TU257_001436"
     CDS             complement(22953..23396)
                     /locus_tag="TU257_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL0834444.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(23466..24317)
                     /locus_tag="TU257_001437"
     CDS             complement(23466..24317)
                     /locus_tag="TU257_001437"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL0834445.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(24532..25056)
                     /locus_tag="TU257_001438"
     CDS             complement(24532..25056)
                     /locus_tag="TU257_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0834446.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(25550..>26032)
                     /locus_tag="TU257_001439"
     CDS             complement(25550..>26032)
                     /locus_tag="TU257_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834447.1"
                     /translation="GEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQ
                     SASPKVPAPKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRKNN
                     "
BASE COUNT         7810 a         6207 c         4893 g         7122 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattgt
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat ttaccccagt aaatgatcta ggactaaata tatctcttat agtaacagaa
     9361 ttttcagtaa aaattgcttc ttgtctatct aaatcaatag aagataaaac tgcttgttta
     9421 tatttttctg ttatagtaac ttcttgagta ccttcatcaa tatttaaata cccatcagat
     9481 tttaaaatag ttattacttc agtttgatca atttctggaa tagaggcatc agcattagcc
     9541 gaaatagtac cgtaagttaa aattgcaagc gcagcgatac tagaataaat aagttttttt
     9601 agtctcataa tctactcctt tttaatctct aaaattaaaa caaacaatct ttaccggtaa
     9661 tagttaattt tactactaaa aataaactcc tttctggtaa aatgaaccac ctaagaaacc
     9721 tacatgtaca gaataacata tattttcctt aaaaataaga ctatatttta aaaaaacaaa
     9781 tgataaaatt aaattttgga agcttttttt ataataaaat aatttatcga tttttccact
     9841 attaagttat ttttgattaa catttttaaa atagttttgt ctatctacat acaatataaa
     9901 gactatatca ctaatgccat tgaactacct tattctaacg ccaagtttga agcgactagc
     9961 aaactgatca aagacatcaa gcgcaatgca tttggattca gaaacgttga caatttcaag
    10021 aaacttatct atgcttgctt tgaacatgac aaaagagaag acgaccttcg tctcctctcg
    10081 tgcttagtta tcagtcacct actatagttg acatggagcc caattaatct aatgatttta
    10141 gcatgataaa aggagctaag gctagctcct tttatttctt attccttaat aattgctggc
    10201 tcttctgtag cttcagcttc ttcgataacc tcaacctcat tgatagcttg cggttcaatg
    10261 ttacggtaac gaaccatacc agtacctgct ggaatgatct taccaatgat aacattttcc
    10321 ttaagcccca atagatggtc ttttttgcct cggatagcag cgtctgtcag cacgcgagtg
    10381 gtttcctgga aggaagctgc tgataggaat gagttagtct caagtgaggc ttttgtgatt
    10441 cccataagca ctggacgaga ggtcgcagga atacctccag agataacaat ctccttattg
    10501 gcatctgtaa agtctgcaat atccattaag gttcctggca gaagatctgt atcacctgga
    10561 tccatgacac gtaccttgcg aagcatttga cgaaccataa cctcaacgtg cttgtctccg
    10621 atttctaccc cttggctgcg gtaaaccttt tgaacctcag caagcaagta ggtctcaact
    10681 gacaaggtat cacgaacctc aaggaggtgc ttaggctgga ttgacccttc tgtaagggca
    10741 gctccacgat tgacctcatc accaacctca accttcatac gcgctgtaaa tggcacaaca
    10801 tattcaccca tgcctgtttt accttgaacg tagaccttct tagtacgagt tgatgcgtcc
    10861 tcttcaatct caataacagt ccccttaacc tctgtgataa ctgcttcccc tttagggttg
    10921 cgcgcttcaa agatttcttg gatacgagga agaccctgtg tgatatcggt attagaggca
    10981 acccctcctg tgtggaaggt acgcatggtc agctgagtac caggctcacc aatagattgg
    11041 gcagcgatag taccaacagc ctcaccaacc tcaaccgcat cacctgtcgc taggttgata
    11101 ccgtaacagt gacgacacac tccatgacga gtagcacagg taaatactga gcgaatggta
    11161 acctcttcaa caccagcatc aacaatcttg cgagccatgt cctcagtgat taattggtca
    11221 gcaccaatca atacctcacc agtttcaggg tgcttgactg atttacgagt gtatcgaccc
    11281 tgcaagcgct cctcaagtgt ttcagtgact tccttgccat ctgtgatagc tcgaataaga
    11341 aggcctcggt ctgtaccaca atcgtcctca cgaatgatga catcttgcgc aacatcaact
    11401 aaacgacgtg tcagatagcc tgagtcagct gtcttaagag ccgtatcagt cataccctta
    11461 cgagcaccat gagttgagaa gaacatttcc aaaacagaca agccttcgcg gaagttagac
    11521 aggataggaa gctccataat acggccatta ggagcagcca tcaagccacg cataccggca
    11581 agctgcgaga agttagagat gttaccacgc gctcctgagt ccatcatcat aacgattggg
    11641 ttcttaggat cctgtgtttc aatcagacgc ttctcaaggg cttcttttgc ctcgcgccat
    11701 gttgttgtga ctgcaacata gcgatcatca tcagtcatca agcctcgacg gaaggcctta
    11761 ttaatttcct caacacgatg gtgagcagcc tcgatgatct cagccttgtt gtcaataacc
    11821 ggaatatcag cgatcccaac cgtcaagccc gcaagggttg aatgatagta gccaaggtcc
    11881 ttcaagcggt caagaaaggc cgatgtttct gttgtacgga aacgcttgaa ggtttccgca
    11941 atgatgttac caagattttt cttcttgaag ggcacattga tcggtaagct atcaataacc
    12001 tcctgaatat tctgacctgg cttcaagaaa tatttatctg gagtgccctc tgtcaagtta
    12061 gcattatttg gctcttggag gtaaggaagg tcctctggca tgatgtcatt aaacaagatc
    12121 ttaccgaccg ttgtcaccat gattttgtgt ctttgactat ccttccaaag cttgcttggc
    12181 atactgtcaa cagcaatacc aacacgacta tgaaggtgaa catagccatt acggtaagcc
    12241 attaccgctt cgtccttgtc cttaaagacc ataccttcgc cttcacgacc agcatcttcc
    12301 attgttaggt agtagtttcc tagcaccata tcctgagaag gtgttacaac tggcttaccg
    12361 tccttagggt taagaatatg ctcagcagca agcatcaaca aacgagcctc tgcctgtgct
    12421 tcctctgaaa gcggcacgtg aatagccatt tggtctccgt caaagtcggc attgtaggcc
    12481 tcacacacaa gcgggtgaag acgaagagcc ttaccatcaa taagcaccgg ctcaaaggcc
    12541 tgaatcccta atctgtgaag ggtaggtgcg cggttaagca ggactggatg ctccttgata
    12601 acctcttcta gaatatccca gatacgctca tcgccacgct caaccatacg cttagctgct
    12661 ttgacgttgc cggcaaattc gcgggcaaca atctcacgta tcacaaatgg cttgaaaagc
    12721 tcaatagcca tctcacgtgg tacaccacat tggtacattt ttagcgttgg acccacagca
    12781 ataactgaac gacctgagaa gtcaacacgc ttcccaagca ggttttgacg aaaacgccct
    12841 tgttttcctt taagcatgtg gctcaaggat ttaagcggac gactaccagg tcctgtaata
    12901 ggacgaccac gacgaccatt atcaatcaaa gcatcaaccg cctcttgcag catacgcttt
    12961 tcattttgca caatgatacc aggcgcatta agctccaaca aacgtgctaa acgattatta
    13021 cggttaatga cacgacggta aaggtcattc aagtctgagg ctgcaaagcg gccaccgtcc
    13081 aattgcacca taggacgaag atctggtgga atgaccggca agatgttcag gatcatccat
    13141 tctggcttat tgcctgattt atgaaaggca tcaagcacat ctaaccgacg aacagccttg
    13201 atacgctttt ggcctgttgc tgtttttaat tcttccttta gctcagcaat ttctgtgacc
    13261 aaatcaacac gctttaggag gtcttgaata gcctctgccc ccattttagc aatgaatgag
    13321 ccatgtccat attcttggat tttttcacga tattcacgct ctgtcaatag tgattttggc
    13381 tcaagcggtg tgtcctttgg atcaataacc acataagccg caaaatagat tacctcctca
    13441 agagcacgag gactcatatc aagagtcaag cccatacgag atgggattcc cttaaaatac
    13501 cagatatgtg agacaggtgc cttcagctca atgtgtccca tgcgttcacg acgaaccttt
    13561 gcacgcgtta cctcgacccc acaacggtca cagacaatgc ccttatagcg aatacgttta
    13621 tatttgccac acgcacactc ccaatccttg gttggtccaa aaatgacttc gtcaaaaaga
    13681 ccctcacgtt ctggttttaa tgtacggtag ttgattgttt caggtttttt aacttcacca
    13741 taggaccatg aacggacctt acttggtgaa gctaatgtga tttgcatact tttaaaacga
    13801 tttacgtcaa ccactagttt tacctttctg cctttgatga cttactagca gctagggcaa
    13861 atagccctag tctagtcatt atttctgtta caaatgttta tgatttagtt gtcttcagtt
    13921 gattcagcaa tatcttgagt ttcctgagcc tgcttttcac gcgctttttc aagatcgtca
    13981 acgtgcatca cgtcatcgtc ttcgccttca tcaagatcac gaagctcaac ttcattatcg
    14041 tcttcatcaa ggacacgcat atcaagacca agtgattgca attctttcac aagaacgcgg
    14101 aaagattctg gtacaccagg ctttggaatt ggcttacctt tggtaatcgc ctcataagct
    14161 ttcaagcgac cattcacatc gtctgactta taggtcaaga tttcctgaag aacgtttgaa
    14221 gcaccataag cctcaagagc ccatacctcc atctcaccaa aacgttggcc accaaactga
    14281 gctttacctc caagcggctg ttgggtaacc agtgagtatg gtcctacaga acgcgcgtga
    14341 agcttatcat caaccatgtg gtgaagctta atcatataca tgacaccaac tgacacacga
    14401 ttatcaaacg gctcaccagt acggccatca taaagaacag tcttagcatc gctatccata
    14461 cctgcttcac gaacagtttc ccaaaggtcc tcagacgtag ctccgtcaaa gaccggtgtt
    14521 gcgatatgga tacccaaatt acgagcagcc atacctaggt gaagctccat aacctgtcca
    14581 atgttcatac gagacggcac cccaagaggg ttcagcatga tgtcaacagg ggttccgtct
    14641 ggcagatatg gcatatcctc aaccggtaca atacgtgaga cgacaccctt gttaccatga
    14701 cgcccggcca ttttatctcc gaccttgatt ttacgctttt gagcaatgta aacacgcacc
    14761 agcatattaa cacctgattg aagctcatca ccatttgcgc gtgtaaagat cttcacatca
    14821 cgtacaatcc cgtcaccacc atgaggaaca cgtaacgagg tatcacgaac ctcacgtgat
    14881 ttatcaccaa agatagcatg caggagacgt tcttcagcag aaaggtcttt ttcaccctta
    14941 ggagttacct taccaacaag aatatcgcct tccttgacct ctgcaccgat acggataata
    15001 cccatttcat caaggtcctt gagggcttct tcaccaacgt ttggcacttc acgtgtgatt
    15061 tcctcaggtc caagctttgt gtcgcgtgtt tctgattcaa actcctccaa gtgaacagag
    15121 gtataaacgt cctccttcac aagacgctca ctcatgataa ccgcgtcctc aaagttgtac
    15181 ccttcccagg tcatgtaagc aacgattgga ttttgaccaa gagccatctc acctttttcc
    15241 atagaagggc catcagcgat aaagtcaccc ttttcaacaa tatcacctat tttaacaagg
    15301 gttcgttggt tgtaggcagt accagagttt gaacggcgga attttgtgat gtggtaaaca
    15361 tcaagtgaac cgtcctcacg acgcacctct actctttcag catctgaaaa gacaacctta
    15421 ccattatgct gggcaattac cgcagcacct gaatcatgag ctgcttgata ttccataccc
    15481 gtaccaacat aaggagcctt tggatcaatc aatggcacag cctgacgctg catgttagct
    15541 cccattaggg cgcggttgga gtcatcgttt tcaaggaaag gaatacatgc tgtcgcaaca
    15601 gcgactacct gcttaggaga cacgtcaaca aagtcaacct gactagcagg aaactcttgg
    15661 ttattacctt ggtgacgtcc catgacaatc tcttcagcaa aggtaccgtc tggattgagc
    15721 ttagaattag cctgagccac tgtaaactca tcctcttcat cagcagttag ccaaacaatc
    15781 tcattagtca ctcggccaat cacacgatca accttacggt aaggggtttg aataaagccg
    15841 tatttgttca gatgtccaaa tgaagacagg ttattaatca aaccgatatt tggcccttca
    15901 ggtgtttcaa tcggacacat acgaccatag tgagtgtagt gcacgtcacg cacctcatag
    15961 ccagcacgat cacgtgtcaa accaccaggt cctaaggcag acaaacgacg tttgtgcgac
    16021 aactcagaca atgggttgtg ctgatccatg aactgtgata gctgtgaaga accaaagaat
    16081 tctttgacag ccgccgttac aggacgaatg ttaataatct gttgtggagt caacacatcg
    16141 ttatcctgta cagacatacg ctcgcggaca ttgcgctcca tacgagcaag accaatacgg
    16201 aattggttag caagcaattc accaactgca cggatacgac gattacctaa gtggtcaatg
    16261 tcatcgacct ttccaagacc ttcagcaagg ttaaggaaat aagacatctc agccaaaata
    16321 tcagccggag taagggcacg aaccttatca tctgggttag cattaccaac gatcgtcacc
    16381 acacgatcag gatcaactgg tgaaaccacc ttgaattttt gtaggatcac aggctctgtc
    16441 accaccgcat aatcgtttgg tgtgtagaca aacttgttca aatccccatc aagctgctct
    16501 tcgattgact caatcacact acgagtcatc tctgttccag cctcaaccag aatctctcca
    16561 gtctcactat ctattagatt ttcagcaata atttgattca aaagacgtgt cttgatgttc
    16621 agctttttat taatcttata acggccaact gctgccaagt cataacggcg agcatcaaag
    16681 aaacgagctg tcaaaaggct gcgtgagcta tcagctgtct ttggctcacc tggtcttaag
    16741 cgttcataaa tttccttaag agcctcatct gtacgtgaat cgctttggtt tttatgaata
    16801 tccttttcaa tggtattgcg aacaagctca ctatcaccaa aaatatcaat aatttcgtca
    16861 tcaccagaaa aaccaagtgc acgcactagc gttgtaaatg ggattttacg cgtacggtca
    16921 atacgagtat aagcaatatc ctttgagtca gtttctagct ctagccaagc accacgatta
    16981 gggataactg ttgagccata accaacctta ccatttttat caaccttgtc attgaaataa
    17041 acaccaggag accgaaccag ctgagaaaca ataatacgct ctccaccgtt gatgataaag
    17101 gttcccattt cagtcataat cggaaaatca ccaaaaaaga cctcttgtgt tttgatttcg
    17161 ccagtttcct tattaatcag gcggaaggtc acaaagattg gtgcagaata gcttgcatca
    17221 tggatacgag cctcttcaag ggtatattta ggctccttaa attcgtaacc aacaaactca
    17281 agctccatcg tgtctgtaaa gtttgagatt ggaagcacat cttcaaatac ttccttcaag
    17341 cctgaatcta agaaatcttg gaatgaatca gtttgaattt caatcaaatt tggtaaatca
    17401 agaacctctt tgattcttga aaaactacga cgggtacgat gtttcccgta ttgaacgtca
    17461 tgtcctgcca agtttttagc tcctttttct ttttaagctt tgctatcaag caaacaattg
    17521 caacatcaat atttgtctta agtggtattt ttagaatctt taaatttttg ttacaaaatt
    17581 gatttttatc taaaaatagg cacaaaaaga gcagctaaat cggaccttat cagtgtgatt
    17641 taactgctgt tctttctagc tggacaatat ttcagctaga ttagacgaca aatagttata
    17701 gatattatac actatttgtc tggaaaatac aactaatttc ttctaccact aaaacctccc
    17761 caggcttttt gatagtctgc gtctgttcca ccaatggcaa acctataggt agttgctccg
    17821 ggtccctttt gagcccaaag gctggttgtt agctctccac cgatggagat ggtttggcca
    17881 ttgatcgtca ctgtacccgg ctttagacca gtggccttca agacagaagc cttgataaca
    17941 ccaggatcca gtgaaaaccg ctgaccaagg ccaaaaagat tgggatcagc ctgactgatg
    18001 gcattaacca aataagccat ataatttgaa ttattattgt atcccgtcag tggtgcaagc
    18061 gaggtattgt catcatggcc tgcccaacca cccaaagtaa cccttggagt agctaagacc
    18121 agccagacat cggtataatt ttcggttgtt cctgttttac ctatccagtc agcacctgca
    18181 aggcttgggt tgatccctgc taatcggctt ttaaaagtgg ttgttgcccc agatgaaatc
    18241 ggccctctca agagctcctg taaaatcgtt gctgtcggag ctgagaaaat acgaaccggc
    18301 ttggcctcat gctgataaac aacggatcca tcactagctg tgatactagc caccatatat
    18361 tgcttttgat aaagaccatt attagcaatc atctgataag cattggtctg ctgggctacc
    18421 gaggtctcaa tcccaccacc aagtggcaga ctttcaatgg aataatcagc aatccgatat
    18481 cccattttac tcatatagtt ttcaacatca acgcccttat cacgcagcag cttttgagtc
    18541 caaaaggctg gaatattcca tgaggtatta agcgcctcct gcaggggcat cattgctgtt
    18601 ccttcactat cgacgtgcat gattttttga ccgctggaat aggtcgtcgg atagttggat
    18661 aggacactag cacttcccat taatccctga tcaatggcag gtccataagc aataatcggc
    18721 ttaatgctag agcctggaga gcgaacagta ttaaaggcat gattgttttg attttgagca
    18781 tagtctctcc caccaataaa gcccaaaaca gcacctgtag cattgtccgt taggacattg
    18841 cccatctgca ctgtcccagt gccatcatct aacaagccac caaactgagc tgccgctttt
    18901 tgcatcacct gatggattgg cttattgatt gttgttttga cagtgtagcc gccatgctgc
    18961 agctcagtta aggctcgctc ctcataggca gccttagtct catcattttt taaatcttta
    19021 gcaggcacct tatctcgctt aatcagatag ctatacatgg ccttttgtgc ctctgccaag
    19081 acagaatagt agaggtaatc atgagtattg gcagtgactg tttcaggttt gataaaatca
    19141 ttgctaatag gatatgcctt ataatcacga tattcttttt ctgtcagcac acctgttcga
    19201 tacatattgt agaggacatt ttgctggcgc ttaatcccat aggccatatc atcggctgat
    19261 tttaactgcc ctgtcggcaa atacggcgaa taaacaatcg ggctttgcgg aagccctgcc
    19321 aaaaaggccg cctgcggaac cgtcaaatcc ttggcagaga ctccaaaaat gccacgcgca
    19381 gcctcctcca cacctgcaat gttttgtccc ttattattac gaccaaaagg cgacacgttt
    19441 aaataatgtg ataaaatatc gtcctttgac atgtaacgct ctaaggccag tgcatagata
    19501 atttcctttg attttcgcct aaaggtcgga tcatcgccca agacttgctg cttaatcaac
    19561 tgctgtgtca gcgtagagcc accacttgac tccccaaagc ccaaaacaga ggccagagtc
    19621 gcacgaaaaa tcgcctttgg cacaatgcca ttatggcgct gaaagttgtc gtcctcagtt
    19681 gagacaatag cctttttgat attgtctgaa atcgcatcat tagcaaccgg tgtcctaagc
    19741 agatccgtat caatgcctga aatcaagcta ttatctgaat aggtaatctg tgacatcatg
    19801 gtcaatgatt caacctgctt gacaagactt tccttacttg gaatttttac cgagtcaatt
    19861 tgactggcta aatagccaaa ggccatacca gcacccagca tgccaaataa aaagacagct
    19921 acataaaaaa agctcgacat gaattttaat gtgcgcaaaa agaccgttcc aaaatcaact
    19981 aattctaatc gctgatgatt tttgcttgtt tgattctttt tccatttcac cataacgtac
    20041 ctcaatcttc attataccaa actttgatta agcttgcaca gccacagtca tttttgatat
    20101 aatgattcgg aaatcataaa gaaaatggag aaagcctatg aatatttttg aagaactcaa
    20161 agctcgtggc ttggtctttc agacgaccga tgaagaagcc cttgtcaaag cattaacaga
    20221 agggcaagta tcctattaca ctggctatga tccaacagct gatagcctgc atcttggtca
    20281 tctcgttgcc attttgacat cacgtcgctt gcagctagca ggacacaagc cctacgctct
    20341 tgtcggtggg gcaactgggc tgattggtga tccgtccttt aaagacgctg agcgtatcct
    20401 acaaaccaag gaaaccgttc ttgattggag ccaaaagatt aaagaacaac tctcttgctt
    20461 tcttgacttt gacaacggtg aaaacaaggc tgagcttgtc aacaactatg actggttctc
    20521 acagattagc tttattgact tccttcgtga tgtcggcaag cacttcacta tcaattacat
    20581 gatgagcaag gattcagtga aaaaacgtat cgaaaccgga atttcctaca ccgaatttgc
    20641 atatcaggtc atgcaaggct acgattttta cgagctaaat gctaagcaca atgtgacact
    20701 gcaaatcggc ggctctgacc agtggggtaa tatgacagca ggtaccgaat tgctccgcaa
    20761 aaaagctgac aagactggac atgtgatgac agtgccattg attacagatg caacaggtaa
    20821 aaaattcggc aagtcagagg gtaatgcgat ttggcttgac gctaaaaaaa catctcctta
    20881 cgagatgtac cagttctggt taaatgttat ggacgatgat gcggtacgct tcctgaagat
    20941 cttcaccttc ttatcacttg atgagattgc tgctattgag gagcagttca acgcagcacg
    21001 ccatgagcgc cttgctcaaa agacacttgc gcgtgaggtg gtgacactgg ttcatggaga
    21061 ggcagcctac cagcaagccc tcaatattac cgaacagctt tttgcaggag ctatcaaaaa
    21121 cctttcagca gctgagctta agcaaggctt aagcaatgtc cctaactatc aggttcaagc
    21181 agaagacagc ctaaatatcg tggatatgtt agtcacagca ggcatttcac catcaaaacg
    21241 tcaggcgcat gaggatttac aaaatggcgc gatctacctc aatggagaac gacttcagga
    21301 tctggattac agcttatcta cagcagatcg cattgacaat cagttgaccg tcattcgccg
    21361 cggcaagaaa aaatacgctg tactaaccta ctaatcacag acagctagga aaatcttgct
    21421 ttggatgatt atttttgacg tataaaggac agcaggttaa ccacaaggaa gatcgcaata
    21481 aaaatcatcg taatggtcgc acttgccggc gtttcccaaa aataggacaa gaaaatacca
    21541 gacagcatgc ctgtaaagcc aatcataatc ccaagaaaaa taactgattt aaagtttttc
    21601 ccaagccgca tagcaatact tgctggcaaa accataatcg ttgataccaa aagggcccct
    21661 gccgctggga tcgttagagc aatagcaaca cctgtcacaa tattaaacaa gacagacatg
    21721 acacgcaccg gcaagccatc gacgtaggct gtgtcctcat cgaaggtcaa gatatacatt
    21781 ggacgaataa ataatatcgt caaggctaaa ataatcaaag caatgacaaa taaggcagca
    21841 acctgctccg tactaatagt aatgatagag ccaaaaaggt attgctccaa gctcatacta
    21901 gaagagctag ttgacttact catgataatc aaggaaatag ccagccccaa ggacattagg
    21961 atagctgtcg aaatctccat atagtgctta taaaccaccc taagatattc tagcaagatg
    22021 gcagctagca ccaccacaat aatcgttgtg aaggttggcg aaacaccaag aacaacacca
    22081 aaggccacac cagccagaga aacgtggcta agcgtatcac tcaacaagct ttgacgacgc
    22141 aaaatcaaaa agatacccaa aatcggagca aagatactga tcgccacaac agccataaca
    22201 gcacgctgca taaaatcata agataaaatc tcaagcatgg aatgaccctc ctttgctctc
    22261 atcagcctca gcatcatgaa tgttgaagca acgccaagga agccgttgat ttctaatcaa
    22321 atgaatattg cgatcagcat aagccttgac ctcctctggg tcatgtgtaa tcatcaaaac
    22381 agccttacca tgtctatgag cgctgtggtg catcaactca taaaaagtat ctgttgttcc
    22441 actatccatt cctgtggtcg gctcatcaag cacaaaaata tcggggtcag aagcaaacat
    22501 acgcgcaata accacacgct gcttttgacc acctgataga ctccctattc tcttatgccg
    22561 actatcccac atgccaacag actccaagct tgtccgaaca tgctcctcat cgtgcttact
    22621 tagtctggta aaccaaccac ttctaggata tctgcctgat ttaacaaatt cataaacagt
    22681 cgacggaaag cctgcattaa agctggcaac ctgctgtggc aagtaagcaa ttctcagctt
    22741 tttcccatga atgttctgtt tagctatagt cacctgccca gcccttggct ttaaaatccc
    22801 caaggtcgcc ttgatcaggg ttgacttggc agcaccattt tcaccagtca atgtgacaaa
    22861 ttctccacta tccaaatgat agctgattcc ctctaaaaca ggctcactgt catactggaa
    22921 cgagagattt tccaccgata tgtatctcat tattaccctt ctaactcctc cgcaaaagca
    22981 gtgataaatt tttcaacaat cacctgctcc tccgcagaaa aatgtgccaa caaacgatga
    23041 taaacagcta gtgttttatc gtgatgatgt gtatgctcct tagcgattgg ccttgctaga
    23101 tcagtcagtt caaaataggt tactcgagca tcaacggtat cctttgttcc tgctagcatt
    23161 tcttgcttga tcaagccttt aatcgcttta gttactgctg cttgactgat atttagcctt
    23221 tttgccaaat ctgtattggt tagcttttcc tgtgacaaaa gcatcaaaat atgctcctga
    23281 gtatttgtta atttgacatc actctgacaa gccccaaaga gcagctcatg ctgattttca
    23341 gcctttaaca aaatacgatt aaccaaatta tcaagctttt tttctaaaat tgtcatgatt
    23401 tccctctcct cattaaccag ttaattataa catgacgccc caaaagacgc aacttcaagg
    23461 ctgatctaca gcgttctaac cttgtagact tccttacaaa agcctttcag gctattcacc
    23521 acacgattgg cctgcttttc tgtttgacat agggcaaata ccgttggacc acttcctgtc
    23581 atcagggcaa tgtctgctcc tgactgcagc attttatcct taaccttttg aataaacggc
    23641 cgtttagcaa tggaaatatc ctctaaggaa tttcccatcg ttgcaagcaa gcgctgataa
    23701 tcacctgcct caatggctga aaccagatcc tcaatcggca ctcgagatat cgtctcacaa
    23761 tcaatatccc aaaaaatcgt tctagtagaa atgccaaatt ctggcttcac tagaaccacc
    23821 caagaggaca agcggccatt gattggctta accacctcgc ctttgccagt cacttgggcg
    23881 cagcctgcaa aaagacaata aggcacatcg ctaccaatct gcatgccaat gtcaatcatc
    23941 tgacggggac taagctttag ctgccacagc tgattcaatg ctctgattgc tgcagccgca
    24001 tcacttgagc cacctcccat accagcacaa acaggtaccc tcttatccaa gaaaatagag
    24061 acacctgttg agatttgaaa tcgctctttc agcaaataag ccgccttgta aacgtcattg
    24121 tgctcattaa taggcaatct agggcaatta gaggtcaata aaatcctatc ctcctctaaa
    24181 tgatccactg taatataatc acaaagatct acactaacta gaaccataga taggtcatga
    24241 tagccatctg gtcgcttgcc ttgaatatct aagcctagat ttatttttgc aggagctctc
    24301 tcaatgattg cagtcataat actcctttat ttgatgtcat tatagtatca aatatacaca
    24361 atcttcatga aaaattcaaa taaatacagt tagtatctaa tgatgcatag acagcgtgtt
    24421 tgtatcaaaa cagccaacca tttgtcccta ctagcgtgag gcttcaccag atcagcagcc
    24481 aaaaaacgac aactactagc atagcaagca aagctaagac agcagcagtc tctatgacca
    24541 cttgatcgct ccatattgcc ccactaactc aaagcacata tcaatcttgc tcttaaagta
    24601 gggaataaaa ataccagcat caatcatggc taaaatctca tcacgactag cccatcgaac
    24661 agcctgtacc tcctctgtct gaagaactag cttccttaca tcaacagcct gcaaaatcaa
    24721 aaaagtatcg tcaaagccat tatcaaaggt aattgaaaaa tgaggcctta caccagctaa
    24781 atcaagagta agtcctagct cctccttcag ttctctcatc actgcctctt gtgacgtctc
    24841 acctgcaaga gcgctgccgc ctaccgttat atcccaatag ctgggccaac cctctttatc
    24901 cttttgccgc tgctgaatca gcatttctcc cttgtcatta aagacacagg cgtgaaccac
    24961 taaatgataa gcaccctcta caaaagcagc tccacgctcc atgagtctac cagtcttaag
    25021 acgattcatc gtataaatgt cccaatactc aaccatacaa acacacctcc tgatacagct
    25081 attaccagat ccagtatatt aatcatatca caataagcat atccaaaaca accaggtcca
    25141 gacaaaacaa caattaccaa cctagcttaa ttcttttttc tacaattccc taccttaaaa
    25201 tgcctcgcat agaaaatgga caaaaagatc tgttttcccg agacgtatca aaaagctcac
    25261 cacgctaaca aactggtagt taagatcccc aagcgtctta ctcagttaac gatatggtga
    25321 tacacacagc tgacttgcct catcatatta gttacaaaaa accttaaagg ctcaacccaa
    25381 aagcacacca actacatcac cccatgaaag aggaagacaa aacatctact gctgcaagca
    25441 aaaagagacc ccattagggc ctctctagtg ctcatatcag cttttaaact aatcaatcgc
    25501 cttcaagcta aaggctatca tttagtagga gaaagttgca aaagctaatt tagttgtttt
    25561 ttctttttag agttagcagg cctgcgctgg caatgacgcc gagagctgca agggtgaaga
    25621 atgggtgatt tgtctctcct gtagctggta atataccctt ttgagctgct ggagccgctg
    25681 atttgcttgg tgctgactta ggcgctggta ccttaggact agctgactgc tgctctgaag
    25741 tctttggtac ctgtggagca ggagattgct ccggggcctt tggagctgat ggtttggtat
    25801 cctttccttg ctcgcccttt tcaccgcgtt ggctttgttc acctttttca ccgcgttggc
    25861 cttgttcacc tttttcgcca cgttggcctt gctcgccttt ttcgccacgt tggccttgct
    25921 cgcccttttc accgcgttgg ccttgttcac ctttttcgcc acgttggcct tgctcgccct
    25981 tttcgccacg ttggccttgc tcgccttttt cgccacgctg gccttgctcg cc
//
LOCUS       DARYJX010000034        25434 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYJX010000034 DARYJX010000000
VERSION     DARYJX010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25434
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(152..742)
                     /locus_tag="TU257_001440"
     CDS             complement(152..742)
                     /locus_tag="TU257_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834448.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
     gene            1265..3307
                     /locus_tag="TU257_001441"
     CDS             1265..3307
                     /locus_tag="TU257_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0834449.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            3309..3596
                     /locus_tag="TU257_001442"
     CDS             3309..3596
                     /locus_tag="TU257_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0834450.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            3609..4952
                     /locus_tag="TU257_001443"
     CDS             3609..4952
                     /locus_tag="TU257_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL0834451.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            4955..5812
                     /locus_tag="TU257_001444"
     CDS             4955..5812
                     /locus_tag="TU257_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0834452.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            5809..6741
                     /locus_tag="TU257_001445"
     CDS             5809..6741
                     /locus_tag="TU257_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL0834453.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            7293..9188
                     /locus_tag="TU257_001446"
     CDS             7293..9188
                     /locus_tag="TU257_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL0834454.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(9388..10428)
                     /locus_tag="TU257_001447"
     CDS             complement(9388..10428)
                     /locus_tag="TU257_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL0834455.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TU257_001448"
     CDS             complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TU257_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL0834456.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TU257_001449"
     CDS             complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TU257_001449"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL0834457.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TU257_001450"
     CDS             complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TU257_001450"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL0834458.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            14288..14358
                     /locus_tag="TU257_001451"
     tRNA            14288..14358
                     /locus_tag="TU257_001451"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14320..14322,aa:Cys,seq:gca)
     gene            complement(14465..15532)
                     /locus_tag="TU257_001452"
     CDS             complement(14465..15532)
                     /locus_tag="TU257_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0834459.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(15659..15934)
                     /locus_tag="TU257_001453"
     CDS             complement(15659..15934)
                     /locus_tag="TU257_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0834460.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(15924..16142)
                     /locus_tag="TU257_001454"
     CDS             complement(15924..16142)
                     /locus_tag="TU257_001454"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL0834461.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(16158..16679)
                     /locus_tag="TU257_001455"
                     /pseudo
     CDS             complement(16158..16679)
                     /locus_tag="TU257_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            17068..17274
                     /locus_tag="TU257_001456"
     CDS             17068..17274
                     /locus_tag="TU257_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834462.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
     gene            17324..17479
                     /locus_tag="TU257_001457"
     CDS             17324..17479
                     /locus_tag="TU257_001457"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834463.1"
                     /translation="MVTKFSEEIKIVRTKSSVYVNSVLDVADKKDPASVVAVAELLKA
                     YKSLTEL"
     gene            complement(17480..17683)
                     /locus_tag="TU257_001458"
     CDS             complement(17480..17683)
                     /locus_tag="TU257_001458"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834464.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            17743..18204
                     /locus_tag="TU257_001459"
     CDS             17743..18204
                     /locus_tag="TU257_001459"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834465.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGNRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            18346..19062
                     /locus_tag="TU257_001460"
     CDS             18346..19062
                     /locus_tag="TU257_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL0834466.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKEVRKYFIQVEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            19096..19245
                     /locus_tag="TU257_001461"
     CDS             19096..19245
                     /locus_tag="TU257_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834467.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(19242..19442)
                     /locus_tag="TU257_001462"
     CDS             complement(19242..19442)
                     /locus_tag="TU257_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL0834468.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            19553..19837
                     /locus_tag="TU257_001463"
     CDS             19553..19837
                     /locus_tag="TU257_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0834469.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            19834..19980
                     /locus_tag="TU257_001464"
     CDS             19834..19980
                     /locus_tag="TU257_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834470.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            20184..20429
                     /locus_tag="TU257_001465"
     CDS             20184..20429
                     /locus_tag="TU257_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL0834471.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            20591..20974
                     /locus_tag="TU257_001466"
     CDS             20591..20974
                     /locus_tag="TU257_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL0834472.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            20955..21188
                     /locus_tag="TU257_001467"
     CDS             20955..21188
                     /locus_tag="TU257_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834473.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            21185..21325
                     /locus_tag="TU257_001468"
     CDS             21185..21325
                     /locus_tag="TU257_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834474.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            21334..21540
                     /locus_tag="TU257_001469"
     CDS             21334..21540
                     /locus_tag="TU257_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834475.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            21675..22403
                     /locus_tag="TU257_001470"
                     /pseudo
     CDS             21675..22403
                     /locus_tag="TU257_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            22580..23791
                     /locus_tag="TU257_001471"
     CDS             22580..23791
                     /locus_tag="TU257_001471"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL0834476.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            23784..24620
                     /locus_tag="TU257_001472"
     CDS             23784..24620
                     /locus_tag="TU257_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL0834477.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            24805..25146
                     /locus_tag="TU257_001473"
     CDS             24805..25146
                     /locus_tag="TU257_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834478.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
     gene            25143..>25434
                     /locus_tag="TU257_001474"
     CDS             25143..>25434
                     /locus_tag="TU257_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834479.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASKLRLIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLI"
BASE COUNT         7664 a         4720 c         5481 g         7569 t
ORIGIN      
        1 tcagtcttta ttttttgtta tgtaaaaagt ataggtggtt atggccgaat agaaaactag
       61 ttttggagta aatgataagg ataagcgatt gaaacaatat gctattgctg tataaactga
      121 cattacaata ataaaataac aaatatagtt cttaagccca cgcatttata cgaccgttat
      181 ttgggtgata atctcgagca tcgacatatt gtgctagggc atatccgaca ttatagtaaa
      241 tgtttattac tgagaatgca gctctaagta aaccggaaat aaatccggtt agtacaccaa
      301 gtcgttgagc tgcagctttt gcagctcggc taagtacagc tcgagcggca gctactccat
      361 gtttggcaac gtactttccg atggttgcat atccactaat taacccgcct acaataacat
      421 caaaagccca agcgaattca tctaaggtta ctccttgccc gtcccataca ctagctctaa
      481 aagtgtatgg actcatggct ttatacgcaa tttcacgcat ttcttgttct gttaaatttg
      541 gataaagagc ttttttctct tggattaatg tatctaactc actttttgaa atttctagag
      601 gttgtgataa tttttcttca attacttttt cttcctgttg aattttagtc acttcactag
      661 catatacaat ggaaggtaca gtgttagcaa tgagtaataa ggacgctatc attgcgatga
      721 tcaattgttt tacttttttc attttgaatt tcctttctga aaacgatggt gatctactaa
      781 gggttaatta gctttactcc tttctaacca agatggtagt tatttgtcat ttaataagat
      841 atcttatagt ttcattatat tattaaaata ataaaacaca agtctttttt ggtaaccgtt
      901 ttcgtggtat aataaaagat taccagttaa ctattaagtc tgtaatcttg ttttaggctt
      961 atatctagag ttatcacatg ctgatgaggt caatcagttt ttttgattat ttggaacatt
     1021 tttgacggtt attactccaa agagctttag ctttggcttg gacttaggaa atcatgggga
     1081 caattgctta gcggcagaga tgggcttgtt tgctctttat tgatagttag gaggagctgg
     1141 tagcctgttt agattggcat cttgagccca agggctgttg atgatgttgg ataagaaatt
     1201 gtgcccaatg gggactagtt tattgtaacc gttttcgata gaatgaattt agaaaggaaa
     1261 tcaaatggtt gatagcaaag cagttgtcat tttgatgacg ttgatgactt atcaagactt
     1321 atcactttac gagctgagtg ttaagacaaa attcaccatt agagagatta aggaccgtat
     1381 tgatgagctg aatgagtttt tggctcagca tgagctctca gagctagatg caacaaggtc
     1441 tggctatcgg atcagtcagc agcttaaggc tgagtcagat catttgttta cgttgattaa
     1501 tgctgagcag gtttatcttt ctcaggcaga gcggatcaat cttatctatc tgtatacctt
     1561 ttgccgcagg gattttgttt caaatagtca ttatcaggac tttttaaagg tcagcaagaa
     1621 cacagccttg acagatatta aggccttgcg gcagaagctg gcagatgttg acttggaatt
     1681 aaagtatacc agagcaagcg gctatatctt agttggtgat gagattaata agcaccggtt
     1741 ggctttagta atgattgcta ctttgcttaa atctcctatt ggcttgtggg ccttggacta
     1801 tattttggct tcttggcact atcaggtgtc gtttgaagcg cttgaaaaac gtgtgagcca
     1861 tttttatcag acctttcaga tgtctccgat ccttgatcgt ctgcaggtct gtttgtacgc
     1921 tgtcatcttt attttatgtc gttaccaaag acgggttgat agggtcaagc aaagacaggt
     1981 agtggtttct gagcagctgg atcagctaac ggcccttttg gtggcagaaa taatgcagca
     2041 attgtctctt aagtatcagc tatttgaagc tgatgaggcc tattttcaat tgctgttagc
     2101 gggctgcttt gagggtgagg gtactgttgg tgatgatttc tttgaatcac taaccgttgc
     2161 gattgttgat caaatgcagg gggttgcttt actaagcttt agtcaggcag atcagctcaa
     2221 ggagaatttg aaaaggcatt tgattccagc ctattaccgt ttgcgctatg gtttgccaag
     2281 tgataatgat tataccttgc ggattaagga tagttattct gagctttttg acttggtaaa
     2341 gcagtctctg gagcctttag ccaaggagct gggtagtcct ataccagata gtgaaattgc
     2401 ttattttgtt cttcattttg gaggctattt aaagcagcag ggaagagatt ttcatcgtca
     2461 agcctatcag gctgtgattg tctgtcctaa tggtgttagt tcttctttaa tgatcaagga
     2521 gcatttaaag cttttatttc ctgatattgc ttttcggggg ctttcaaggc ttgatcagct
     2581 tgggcaatta gataagagcg gctatgattt ggttttttca acgatacgat tagagactga
     2641 taagcccttt tatttagtcc ctatgataat gactgatgag caggcttttc agctggtcag
     2701 cttggttaat cgtgattttc cagatattgg ctatcggcta gaggttgaag agctgctcca
     2761 tcttatcagc tcatatgcgg tcattcatca aaaagaaaag ctgcgctttg ctttgcagca
     2821 atatttaaga caaggtgtga aaagaaagga tattcgacca gtgttacaag acttaattac
     2881 caagaaaacc tatcaatcaa cctcagagca attggggtgg agagaggcta tttatttggc
     2941 ggctcagccc ttgttagaga gtgggcagat tcaagcgagc tacccggagg ctatgattgc
     3001 taaggttgag gagtttggta cttttattaa tctaggtaag gggattgcta tcccacatgc
     3061 gaggccagag gatggtgtga atcaggtagg tatgtcgatg cttgttttag agcacccgat
     3121 ttatttgtta gatgatccta agcaggagat tcgtttgtta atttgtattg ctgctattga
     3181 taatgaaaca catctaaagg ccctgtctcg gctgacgacc attttaagag acaatgagca
     3241 ggtcaaggct ttacttgcgt ctaaatcatt tgaggatatt aaaactatta ttgcagagga
     3301 ggcataaaat ggcattaaga attggtacag cctgtggttc aggcttaggg tctagcttta
     3361 tggttcagat gaatatcgaa tccgtattaa aggacttggg agtaaccggt gttgaggtgg
     3421 agcattatga tcttggtggc gcggatccca cagcggcaga tgtgtggatt gttgggcgtg
     3481 atttggcaga ctcggcagag catctgggag atgtgaggat tttaaatagt atcattgata
     3541 tggacgaatt gactagtctg gtaaaggcta tttgccagga aaaggggctt gtttagaagg
     3601 aggataagat gacattttta cttgatattg ttagcacacc agctattttg gttgccttga
     3661 ttgctattgt tggtctctta cttcaaaaaa agcctgctcc tgacattgtt aagggaggca
     3721 ttaagacctt tgttgggttt ttagtggttt caggtggtgc aggtatcgtg caaggctcac
     3781 tcaacccttt tggaacgatg tttgagcatg cctttcatct gtctggtgtt gtgccaaata
     3841 atgaggctat tgttgcagtt gctttgacga cctatgggtc agcgacagct ctgattatgt
     3901 ttacaggaat gatctttaat attttgattg ctcgctttac ccgatttaag tatatcttct
     3961 tgacagggca tcacacactt tacatggcct gtatgattgc tgtgattatg tctgttgcag
     4021 gcttgacgtc agtgtccttg attgtgtttg gtgggctggc cttagggatt atcatgagtg
     4081 tttcaccggc tcttgtgcaa cggtatatga tccagctgac tggtaacgat aaggtcgctt
     4141 tggggcattt tagctctctt ggttattggt taagcggttt tgtaggaggt cttgttggag
     4201 acaaaaccaa gtcaacagag gacattgatt ttccaaagag ccttgctttt ttgcgtgata
     4261 gtacagtaag cattacctta tcaatggcaa tcatttattt gattgtagct atttttgctg
     4321 gtcctacttg gattagtaag gaattatcct ctggcacaca tggcttggtc tttgccttgc
     4381 agttggcagg acagtttgct gcaggcgtct ttgtgatttt agctggtgtt cgtttgattc
     4441 tgggtgaaat tgttccagcc ttcaagggca tttctgaaaa attagtgcca cattctaagc
     4501 cggccttgga ttgcccgatt gcctatcctt atgcccccaa tgcagtgctg attggctttg
     4561 tttctagctt tgttggtggc cttgtgagca tggctgtgat gatcgtaagt ggaacgacag
     4621 tgattttacc tggcgttgtg cctcatttct tctgtggtgc cacagctggt gttattggga
     4681 atgcttctgg aggtgtgcgc ggtgcaactg tgggagcctt tttacagggt gttcttatta
     4741 gctatcttcc gattttcttg atgcctgttt taggcggctt gggctttgag ggctcaacct
     4801 tctcagatgc cgattttggc ttatcaggta ttttactagg aacacttaac agcataggtg
     4861 gtgtgacagc tattgtgatt ggtatttttg tgatattagc tggacttgtt gggctttctg
     4921 ttgttggaaa atcagtagct aaggaggaat aagcatggtt ttgagtgatg agcctctaac
     4981 agatgtgaag cgattcgcag cagagattcg tctaaatacc ttggagactc ttaatcatct
     5041 tggctttggt cattatggcg gtagcttgtc tattgtagaa ttgctggctg tgctttatgg
     5101 agaaatcatg cccatgacac cagagctctt tgtccagtca gatagagatt atctggtgtt
     5161 atcaaaggga catgcgggtc ctgccctcta tagcactctc tacttaaagg ggttttttga
     5221 taaggccttt ttacagtctc ttaataccaa tggaacaagt ctgccctcgc acccagatcg
     5281 tctgttaacg cctggtattg acatgacgac aggctctctt ggtcagggaa ttagcgtagc
     5341 aacgggcatt gcctatgctc aagcgcttga gcagtcacca cattatacct atgcaatcgt
     5401 tggtgatggg gaattaaacg agggccaatg ctgggaggct atccagcttg cggcacacca
     5461 gcagctaagt catttcattg tctttgttga tgacaataag aagcaattag atggaacaac
     5521 cgaggcaatc tgtcgtccag gtgattttgt tgaaaagttt acggcatttg gctttgaaag
     5581 cttacgtgta gatggtaggg atgttcaggc tatttttgaa gccatcaggg ctttgcaggc
     5641 gtcatcaagt cataagccca agtgtatcgt cttagatacc gtcaagggtc agggtgttag
     5701 ccagctagag tcaatggcag ctaaccacca tctaagacca acagcagccg aaaaggagat
     5761 gcttgctgcc gctgtcagaa agctacgagc tagtttggag gtgacaagat gactcgagca
     5821 agtcaagaaa tgcgtcatgt ttaccgagat ttcctcattg cagccaacca agagcaccct
     5881 gaggtagtcg tcttagaggc agatttatca agctcaatgg ccaccaacca tttggatcag
     5941 gtgtttggca agcgctatat taatgtaggc attatggaag cagaaatggt cggtctggca
     6001 gcaggcctgg cgattaaagg ctataagcct tacctacaca cctttggtcc ctttgcctca
     6061 cgtcgtgtgt ttgatcagct gtttctttca ttagcctatg cccagctagg cgcaacggtt
     6121 attggctctg atgccggagt tagtgcggaa atgaatggcg gcacccatat gccctttgag
     6181 gatctgggac tgctgcgcct gattccaagg gctattgttt atgaggtcag tgatgacgtt
     6241 caatttaaag ctgttttaaa ggaaacccta tcactcgatg gcctaaaata cattcgaacc
     6301 attcgtaaaa agccagaggc tatttatcaa gggcatgagg acttttctaa tggctattgc
     6361 ctattgcgtc aaggaaaaga ccttgtgctg gcttgctcag ggatcatggt caaaaggtgc
     6421 ttagaggtag ccgataaaat ggcagagcag ggctactcta tcggtgtgat tgatgttttc
     6481 agggtaaagc cactggccga tgagctaaag ggtctactta caggcagtcc tgttctaacc
     6541 gttgaaaatc ataatcgtat cggtgggctt gggagtgcta tctgtgagct actggctcag
     6601 gaaagtaata ctccagttta ccgtatgggg gtggacgaac gtttcggtca ggtcggacag
     6661 atggattatc tattagagga ataccagctg acgccagcag ctattgagca gcaggttttg
     6721 aggattttag cggcagatta gctaaaaaag cctatcaggt gtaccacacc caaaaagctg
     6781 gaccttatag attaggattg agctttgtat gaaacagggt tcagtccttt tagttatgcg
     6841 ctttcagtcc ctttcactct gtaggcgtga aataatgatt gataactctt gatttcacct
     6901 tctaatttta atgtcataga aaaagttctt aagctttagg ttttatcttc acctttgggg
     6961 tgcaattctt ttgtcaggac tgatagggcc ttttgctatt actgctgagt ttttggcata
     7021 ttgtgagggc tgttttcatg aagctggaga agaatcgttt gatttcttag tgattgttca
     7081 gtttttatga ttaatcttac tgataaaagg accaaagcag ctaagcgttt actatctatg
     7141 ccatgcgata cgaagaatga gcttattttt gaacagaaag ttaatataaa acgagtattt
     7201 tgaacgattt tttggtaaaa tgtaagagat tacattatga ggagtaaaag ctagtcctaa
     7261 cataatggtt taatttaaaa aaggagcaat tcatgacaac atatcaagaa gatttttatc
     7321 aagccgtcaa tggtcaatgg gcagaaacag ctgttatccc agacgataag cctcgtacag
     7381 ggggcttttc agacctagca gatgagattg aggacttaat gctgaccaca acagatgctt
     7441 ggttggctgg tgagcatgtt cccaatgacg ctatattaga aaactttgtc aagtttcacc
     7501 gcttggttgc agattatgac aagcgtgatc aggtgggcgt agcgccagcc ttggacttaa
     7561 ttgaagaata caaggcctta ggatcttttg ccgagtttgc tagcaaggtg gctgattatg
     7621 agctaaatgg aaaaccaaat cagtttccat ttagtgtagc accagacttt atgaatgctc
     7681 agttaaatgt cctttgggca gaggcaccag gtcttatcct gccagatacc acttactatg
     7741 ccaaagacaa tgacaaaggc aaagagctgc ttgctatctg gcgtggcatg caagaggagc
     7801 tattgcctaa atttggcttt tcacatgaag aggttaagga cttgctggat aaggttatca
     7861 cgcttgataa acagctggca gattatgtcc tttctcgtga ggaatattca gagtatgcca
     7921 agctttacca cccttatgac tgggccgagt ttaccaagct agtgccagaa ttgcctttag
     7981 ataatatatt tactgtgatt ttaggtgaag taccagacaa ggttgttgtg ccagaggagc
     8041 ggttctggac agaatttgca gctgactatt attctgagaa gaattgggag ctgctaaaag
     8101 cctggctagt gcttacagca gcaggtgctt atcatgctta tttgactgac gagattcgtg
     8161 tgctatcagg agtttacagt cgtgccttgt caggaactcc acaggctatg gacaagaaaa
     8221 aagcagccta ttacttagca caaggaccat ttaatcaagc tcttgggctt tggtatgctg
     8281 gtgaaaaatt ttcaccagag gctaaggctg atgttgaaca caaggtagct aagatgattg
     8341 aggtttataa atctcgtctt gaaactgcgg attggcttgc accagcaaca cgtgagaaag
     8401 ccattacaaa gctaaatgtt atcaccccac acattggcta tccggaaaaa ttaccagaaa
     8461 cctatgctaa aaaggtcatc gatgataagc tatcacttgt tgaaaatgct cagaatttag
     8521 ccaaaatttc aattgctcat tcatggagca agtggaataa gcctgtggat cgtagtgaat
     8581 ggcacatgcc tgccaacatg gttaatgctt attatgaccc acagcaaaac caaattgtgt
     8641 tcccagcagc tattctgcag gcgccgtttt attcgttgag tcaaagctca tcagctaatt
     8701 atggtggtat cggtgctgtt attgctcatg aaatttcgca tgcctttgat accaacggtg
     8761 cttcctttga tgagcatggt agcctaaaga attggtggac agacgaggat tatgccgcct
     8821 tcaaggagcg taccgataaa attgtagagc aatttgatgg ccttgactcc tatggtgcta
     8881 aagtcaatgg taaattaaca gtgtctgaaa atgttgctga cctaggtggt gttgcctgtg
     8941 ccttagaggc agctcagtca gagccagatt tttctgccag agatttcttt atcaactttg
     9001 ccaccatctg gcgtatgaag gcgcgtgagg aattcatgca aatgatggca agtattgacg
     9061 tccacgcacc tggtcaatgg cgtactaatg tgaccttgac aaactttgat gaattccacc
     9121 aagaatttaa cattaaagaa ggtgatccaa tgtggcgtgc tccagaggat cgtgtgatta
     9181 tttggtaatc attgctcatt aaaaaaagac taagaggctt tgtacggccc tcctatcgtt
     9241 agaacgtata gtctagcttg tggaggaagg catgcttctc ttagtctttt tgtgttggat
     9301 aggctcgaaa agctcttttt ttaggcgtaa aaaaagattg aagatagctc ttaaaagctg
     9361 tcctcaatct tatgacttat gattagacta gttgttaagc gcagctgcca ttgtagcagc
     9421 aacctctgat tcaaagtcgt tagctttttt ctcaatacct tcaccgactt caaagcgagc
     9481 aaagctaatc gctttagcat tgactgagtc aaggtatgct tcaaccgttt tgctgtcgtc
     9541 catgatgtaa acctgagcaa gaagagtata ggcttggtca accttagtgt tatcaagcat
     9601 gaagcgatcc atcttacctg ggataatttt gtcccagatc ttttcaggct taccttcagc
     9661 agcaagctca gccttgatgt cttcttcagc ttgcgcaatc acgtcagctg ataattgagc
     9721 ctttgaacca tatttcaaga atggaagtgc tggcttgtta accattgcac gtgattcatt
     9781 gtcaagctca atagcgtggt tcaattgtgc caactcgtcc ttgataaatt gtgggtcaag
     9841 ctcagtgtat gataaaacag ttggcttcat agctgcgacg tgcattgata cttgcttggc
     9901 aagtgcttcg tctccgcctt caacaacagt gataacgcca atacggccgc cattgtgttg
     9961 gtaagcgcca aagtgttggt catcagtttt ttcaactagg gcaaagcgac ggaatgagat
    10021 tttttcaccg attgtagctg ttgcattgac ataagcatca gcaagtgttt caccagaagg
    10081 catgataaga gcaagtgctt cgtcgttatt agctggctta ccttctgcga tagcctttgc
    10141 agttgcgttt accaattcaa cgaattgagc gtttttggca acgaagtcag tttcagcatt
    10201 gacctcaaca acagcagcaa cgttaccatt aacataaaca cctgtcaagc cttcagcagc
    10261 aacgcggtca gcttttttag cggcctttgc catacccttt tcacgaagaa gctcaatagc
    10321 cttttccatg tcgccatctg tttcaacaag tgctttttta gcgtccataa cgccggcacc
    10381 agatttttca cgcaattctt ttacaagctt agctgtaatt tctgccattt ttatttcctc
    10441 caaaattaga atcggtcctc ttaaagctcg ctttagcaga gcctttgacc tgctgggttt
    10501 tcttacttaa aaaataacga gatagagcgg aatgctttgc cccgttagac catgttatga
    10561 atagcaagaa gctatcctag ttcaataagc ctgacttaag cttcgtttga accttcaaca
    10621 acctcaacga tttcttcgat tgactctgct tgagtatcag cttcaaatgc aacctctgcg
    10681 tcttcacctt gacggccttc gataacagca tcagccaatt tagcagtgat taatttgaca
    10741 gcgcggatag cgtcgtcgtt agctggaatg atcacatcaa tgtcatctgg gtcagcattt
    10801 gtatcaacca ttgccacaac tggaatacca agcttcttag cttctttaac agcgatttgt
    10861 tctttgtgtg ggtcaacaac gtacatcaca tctgggatac gaggcatatc ctcaatacca
    10921 cctaagaatt tttcaagacg tgcgcgttgc ttgttaagaa gtgcaacctc tttcttagga
    10981 agaacctcaa aggttccttc ttcttccatg cgtttgattt ctttcaaacg agcgatacgc
    11041 ttttggatag ttccccagtt tgtaagagtt ccacccaacc agcggtggtt gatgaagtat
    11101 tgacctgcac gagtagcttc gtcagcaact gcttcagcag cttgcttttt agtaccaaca
    11161 aacaagataa cagcgtcatt agctgctgca tcacgaacaa actcgtaagc ttgatcagct
    11221 aattttacag tttgttgcaa gtcgataacg tggataccgt tacgctctgt gaagatgtat
    11281 ttagccatct tagggttcca gcgacgagtt tggtgaccaa agtgaacacc agcctcaaga
    11341 agttgtttca ttgaaattac tgccatgagt agtttctcct ttatagaaat gtttttttcc
    11401 tctcttagac gtcggcttgc aactccacct gatggcaaca gaatcacaat cgatctaaga
    11461 tgagtatttg ttgtctgcac aactacaaca gtataccaaa aaaagctagt catagcaagc
    11521 ctaaatacac taaaacccac gtcgtacgca tgaggaaaat gcatgccatt attttctaac
    11581 catatgcatg ttttcaatgc atttttgata tgttgacgtt ttgacacgat ccatttttca
    11641 agcgcagctt agttttacta tcaatctttc tgaaaaagaa cacatgaatc atgaaaagat
    11701 atcagagaac ataagtttct tcaagcattt ggcgtacccc aaatgcttga tctatcagcc
    11761 ttgctgttta ttaggcctct aaaaagcaaa aaccagggta aacagttacc ttggtttttt
    11821 gctaacttac tgacgaatca ggtaatcaaa tgctccaata gcagcagtag cacctgaccc
    11881 catagaaata ataatttgtt tgtaggctga atctgtacag tcgcctgcgg caaagatacc
    11941 tggaatattg gttgaaccat atttatcaac aataatctcg ccacgatcgg ttaagctgat
    12001 accgctgtct ttgagccaag ctgtatttgg caccaagcca atctgtacaa agactccttc
    12061 aaggtcaaga tgcttttctt gattgctgtc acgctcgata tagttaagcc ctgtgacatg
    12121 atcgtcccca acaatatcct ttgtagcaac attttttaga atagtcatat tgtctgtttt
    12181 agcagcgcga tcctgtagca ccttgtcggc cttaagctca ggtaagaact caagaacata
    12241 gacatgctta gctaagccag ctaaatcaag tgcagcctca agtccagagt taccaccacc
    12301 gataacagca acgtttttat cttcaaagag aggaccgtca cagtgtgggc agtaggttac
    12361 tcctttattt ttaaactcat tttcgccagg aacattgata ctgcgccatt ttgcaccaag
    12421 cgctagaata gctgttttag ccttcaagac agcgccatta gcaagagtaa cctcaacaag
    12481 gtcttttttc tcaatcgaag tagccagctg ggctttgatg atgtcaacat cataggattt
    12541 agtatgctcc tcaacctggg ccataagctt tggtccctct gtatacaggg ttcctatcat
    12601 gttttcgata cctacagttt ccatgacttg accaccaaag gtctcagcca aaagacctgt
    12661 atttaagcct ttacgagcag catagatggc agcactattt cctgcaggtc ctccaccaat
    12721 gacaaggacg tcatagactc ctttatcagc aaaggcctcc ttagatagag gtcctgcgat
    12781 ttgctcaagc agctgctcaa tagtggcgcg accagaggtg aattcttctc cattcaaaaa
    12841 gacagttggc acagacatga tgccctttgc cttgacttcc tcttggaaca taccaccctc
    12901 aaccatagta tgtgaaatgt tcttattaag aacagccata atgttcaagg cttggaccac
    12961 atctgggcaa ttatgacacg ttaagctgac ataggtttca aagcttaaag gacggtcaat
    13021 agccctgatg cggtcaataa tatcctgctc aatctttggt gcacgtcctg aaacctgtaa
    13081 tagagcaagg ataaaggagg caaactcgtg acctagaggc agtccagcaa agatcactcc
    13141 gctgtcttga cctttttggg taatcttaaa gcttggttga cgtgttaggg tagtctcctc
    13201 aacagtgata cggtctgaca tggcagcaat ttcttcaatg aagtccttga ccttttgtga
    13261 gctatcgtca ctaccaagat aagcttgtag gactaagtca gattccaaaa gattaaggta
    13321 ttgagcaagc tgctctttaa tatcaggact taatgccata gcttttctcc tttgcctgct
    13381 taaattttgc cgacaaggtc aaggctaggt gttagtgttt cagccccttc tttccatttg
    13441 gctgggcata cttcacctgg gtgcttacga acgtactgag cagcacgaat cttatcaatc
    13501 aagctgcttg catcacgtcc gataccatca gcattgattt ccatcatttg gataacacca
    13561 tctggatcaa taatgaaagt accgcgttga gcaagtccat cctcaccaag aacatcaaag
    13621 gcttgtgaaa tagcatgtga tgggtcacca atcattgggt aagtgattgt tccgacaaca
    13681 tctgaatcat cgtgccatgc cttatgaaca aagtgtgtat cagtagatac agaataaacc
    13741 tcaacaccta aagattttag tatttcatat tgctcttgaa ggtcacctag ctctgttggg
    13801 caaacaaaag aaaagtctgc tgggtagaag caaacaactg cccatttccc tttaagatcc
    13861 tcattagtta cagtgataaa ttttccattg tgaaaagctt gggctgaaaa ttcagcaatt
    13921 tcctttccta ctaaagacat gtcatgtcct ccttttttac atttgatacc tgtattataa
    13981 gctaagaaat cttatctgtc cacttgtaaa ccctagattt atcaaggttt ttgatgttct
    14041 tttctaacaa tttcatatgt gaatttagtc acactgttta aaactattct aaataataga
    14101 aaactctgat aatatcaaag attcttgaaa ataagttttt gaaataattt taatattatt
    14161 aaaaatgatt ttctgattta aactctaaaa aataacataa accgaaaaaa ggagcagcct
    14221 gctaaaaaat agctgctatt tttatcttga cgaatgctat caactagggt aaaatagttc
    14281 ttgttatggc ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt
    14341 caaatccgtc taccgccttt tatatacaaa cgaatccttg attaacctcg taaaaacgtt
    14401 gttaaatcaa ggtttttatt ttttgtggca ggataaaaaa agagaaaaaa agaaataaag
    14461 tcggtcaaaa gtcggtcaaa tttccaaaaa tatcttttat ggcctgattg ttcttttctt
    14521 ttagcttatc tagctgatgg gcatatacct taagcgtaat gttcaaattc tcatgcccaa
    14581 gcaactgaga tatggatatt aggtcaacac cctttaagat taaaaaagat gcgtaagtat
    14641 gacgtagaga gtgattgcgt acaggacgac caacaatttt tttaaccaat ctattgcaga
    14701 gtgaattaga agctccgtag agcaccctat ttagcttatt ttcattataa taattttctt
    14761 taaatgctct aagcaatttt atagtttgct gatcaatggg aatttgtctt tttgattgct
    14821 cgttttttgt ttccttaaat tcttgagttt ttgagtaatc aaacgattta ttaatatcta
    14881 taaatccctt ctcaaagtct atatcgctcc aagttatccc ggtcgcttcg gcgaatcgta
    14941 gtccagtcac tgctatgatg tataaagtaa aataggaaac atactggtat ttctcactcg
    15001 ttactttgat tagatttaga tattcatctt cttcaaggaa atcaaattct tttgctctag
    15061 cttctttttg agattttaca atcgcacctt cggcaaaatt tgttttgata agcccatctc
    15121 taactgctac attaacagct ccttttattt gatagtggag tttttcgagt gtttcttggg
    15181 catatttttt ggcaaattcg ttgattgttt tttggtaaaa ggtatgcgtt acattattaa
    15241 gcttaatatc accaaaatat tttttgatgt gcttaagatt tttagtgtaa gtttcccaag
    15301 ttttatcgac aacatgcgga cgtttgtaga ttttagccca ttccttgcaa aaatcataaa
    15361 gtgatatatc atcaatatct ttatttagct cagcctcgac tttaatcgca gctgcagaag
    15421 ccaatgcttt tgtcttaaaa ccacctttgg atttttccct tttgttcccc tgactatctg
    15481 tgtagtaaat acgataagac cacttgtcgc cgcgttttct aaattttgcc attgttaatt
    15541 acctcatttt tatgttaaaa tgggtacagt aaagagacct actgcgaagc aggtttttta
    15601 ctatacagga tttgcctcac gctcagactc gccaaagttt gagagcgtgg ggcttttttt
    15661 aacgtttgat tttatagact gagcttcgat gctctatttt aaaaacttcg atgacaactt
    15721 cgtcatcaat aatctcagct aaaatacgat agtttcctaa acgataacgc cactctcctg
    15781 tacgattagc ttgtaaagct tttccgtatc tccttgggtt atctgtgcca tcaaggttag
    15841 tcattatcca ctgatagagt tgtttagcag tagatctatc taattttttg agttgttttt
    15901 tggctttttt agtaaacaat actttataac gcaaaaccta gctccttcgc tacatcttcc
    15961 atgctaaatc gtgtcccatc gtcctcagcc ttagcttttc tcaattcgta caaatcttta
    16021 gcatcttcaa tgatttccaa aaactggtca actgttagat tggaggtgtc aatgttattt
    16081 tctttgatgt aatctgcgat ataagcatcg tctttttcaa ggtttaatgt cattgcaatc
    16141 atagtatttt tctccttcta tatttctact ggtgtaaagc tgccgacgac atcatagatt
    16201 ttgatgtaag tatcttctgc tggcgggtag tcgataaaga tatcattgta ttttttattg
    16261 agagatacta atctaagccc gtcttcctct gtgtatactt ttttaaaata ggtctgtccg
    16321 ttatgcacaa ctatacatag ctgaccggca tatgctgaca tgccccgatc tacaatatag
    16381 agcatatctc cttgctcgta ctttggtagc atactatcgc cccgcactcc aattgcatag
    16441 tcgtagtgag gtggttcttc gtcagtgtag acagtatatg tgtcatattc atctgcttca
    16501 aatccacgac caaagccact tgcggctgcc gcgtaagtta cgccttgaac cgaaaataat
    16561 tcttcatgcg tagaaacaac tttattttgt tcttccaatt gctccttggc aaagtcaagg
    16621 actttttctt gtctaggttg ttctagttgg ttgtagatgg acactatttc agatgtattt
    16681 tttggggcat ctagcagaga cgaaaacacc tcgggtctga tacctaaagc tgagcaaatt
    16741 tttatggcat tctcgacgtt agcattcatt attcctcgct ctaatatcga gcgaaccgtt
    16801 gagtaaggca tgttgttttc ttctgcaaaa gattttacag agctataacg agaaagtata
    16861 agatgtttta gattttcttc attcatggct gcctctcttt ctgatttcat tataacacac
    16921 gatttttcgt ttgtctaaca aaaaaacact aagaaatacg aattttagta ttgacaaaca
    16981 cgaaaaaaag tattaaactt gtatcaagct cagatgagct taactttaaa accaaaaaca
    17041 cgaaaaatcg tgttagaaag gagttatatg ttaaatattg ataaagtgcg aaaagaaaaa
    17101 ggcgtagcaa tagtagacat ggctgatttt cttggcgtaa gagctcaaac agtaagcgat
    17161 aaattgcgcg ggacttacga ttttaaattt actgaggctt tggcgttgca acaaaaattt
    17221 ttcccggagt acgatttaga atatcttttt aacaaagcag tagacactgc ttaactttaa
    17281 aaccaaaaac acgaaaaatc gtgttagaaa ggagaaaatc aatatggtga caaaattttc
    17341 agaagaaata aaaatagtaa ggacgaagtc ttctgtttat gtaaacagcg tcttagacgt
    17401 tgcagataaa aaagaccccg cgtctgttgt agcagtcgca gagcttttaa aggcgtataa
    17461 gtcgttaaca gaattgtaat caactatggt gacttatata cgtgacttga tcgagattga
    17521 ccaaaacgat gtattgagcg tctgatagtt tcagttcaat aatatttgga ttatcagggc
    17581 actcatttgc aacttggcag aatgtgtgtt gcttaccatt tgtgaacatg attgtaatgg
    17641 tatcagtttc attcgctagt tgttcgataa tatatcgttt catacaatca cctcctttct
    17701 gctcatatta tagcagttaa ggacaactag agaaaggaca ctatgcaagc aaatcgaatt
    17761 ttttacggaa aagaaaaacc aacaaacgca gtagcgggcg attgctggtt tagagataac
    17821 gaattaatga tactcaagga caattgggaa gctagcgtaa acaacttaaa gagccctaaa
    17881 gttatcggag agatagaaat agacctagag cagcatgatg tactgctgac agccagaggg
    17941 aaccgtcctc cactattaat gattgatggg ataatgttgg gcggagtatc taaggtaata
    18001 attataaatg agttatccga gtcttgcgca attgtctctc ttaatgagta tatcaaggag
    18061 aatttgttcc cttttgacga ttttgaatca cttcaaaggt tatttcaaaa gggccatcag
    18121 aaattatccg tacgggaact ttgcttagaa aaacgtttag gtgagcattc ttatcaagac
    18181 catcgaaaaa gctgcgatga atagtaaaag ttttcttacc gctcgcaaga gctttctcgt
    18241 aatcctgagt cagtagttta acagagagat ctaattgata gtcgtacact tttgtttatc
    18301 ctccttccac taggataact acattataca acagaaagga acaacatgaa tcaactaata
    18361 aacatcaccc taaacgaaaa tcaagaacca gttgtcagtg gtcgtgattt acataaagta
    18421 cttgaaatca aaacagctta taaagattgg tttccaagaa tggctgaata tggttttgaa
    18481 gaaggtcagg actttagctc atttttgagc aaaagtacag gaggtcgtcc tagtcaagac
    18541 cacgttctaa aactagacat ggcaaaagag attgctatgt tacagcgtaa cgagaaatct
    18601 aaagaagtcc gtaaatactt catccaggtc gagaaagact tcaacagccc agagaaaatc
    18661 atggcaaggg cgttgctgat ggcggacaag aaagtgcata aattagaagc tcagattgag
    18721 gctgaccgac ccaaagtact atttgctgat gccgtaagtg ctagcaaatc atcttgtctg
    18781 attggtgagt tagctaaaat cctgaaacag aatggaatca atattggtca gaataagcta
    18841 tttcagtggc ttagaacgaa cggttatcta attagcagac gcggcgagtc atggaatcag
    18901 ccaacgcaaa aaagtatgca gcttggattg tttgaactca aaaaaacagc catcaatcac
    18961 tctgacggtc acactacaac aaatgtaacc ccaaaagtta ctggtaaagg ccagcagtat
    19021 tttattaata aattccttaa tcaggaatat ctgccagttt agaaaggaaa caaaaccaac
    19081 gaaaaggaga aaagtatgcc agaggattta atcaaacaac tagaagctgg ttcagaattt
    19141 ctagcaaaga catgtttaca tagcaagatt attatcacgg tggatggtgt tcggcttgtg
    19201 gaaacaaaag agttccaccc agtgagcgga actctactag attagacaat acgtgtataa
    19261 gtgtgtatct tagctaatct atgaatattt gagccaacag acccaacaag aacagaacgg
    19321 tattccgttt ggcttacatt gtgataatgg taaatagaac cattattaaa ctcaacttcc
    19381 aaagtgttat tttcccaacc aacacttcgg acgttactag atgaaacgta ttgacgttgc
    19441 ataacttttt ctcctttccg cgatgatagc tttattatag cacgcaagga gaatacaaaa
    19501 aaagtccgac gggaatcgga ctcgacaata atatttatga ggtaatttta tcatggatag
    19561 tagattatta caaatgcttg atgagtttga ggcgggtctg atagaccgta aaatcaaagt
    19621 cataggcatg cttaataacg aaacggaaat ttatccgcta gagcttaaca aaaagcaaat
    19681 cagtaagatg ctgggagttg atcctaaaac atttgacgta agatttaata gccacaaaga
    19741 ttttccgcgc atcgaaacgg gaggtcggga aaaataccca cgagatttag ttattgagtg
    19801 gtatagcaaa aactgggaaa ggacggggat aagatgatta aaaaactatt taactttatt
    19861 tttgcaaagc caaaagaaga atcaaggcaa ccttatcaac aaccgagagg ttttctggat
    19921 tttgaaacag gtaaacgaat tgaaatagat ccgataacaa gaaaggaata cttcgtatga
    19981 tgcatcaaat taatatatcg cttagaaatt ttgtcgagac tggagagatt gacaacatct
    20041 tcgacatttt tagaatttta gatttctact ttcgggaggt ggtcagctga tgcagtacat
    20101 ttttcaagac gttgagaggg agttacacga gcgttagtaa tgagtttgtc aacgataaaa
    20161 aactttataa caaggaaaag ggattgttgt tgaccattct tagcaatagc gatgagtggc
    20221 gagtatatcc ggaggaattg gctaaacgtt gcagagatag tgttgacgct gtcagaactc
    20281 agctaaaagc acttgagaaa gctggataca tcagaagtta tcggaagtcg cttggcgggc
    20341 gatatggtac cgaaacccat agattttgct cagacacaaa aataagtgat gaggtttttc
    20401 aagagctgct taaagaatta aattgctaat gtgcaaattg ctaatgtgca aattgctaat
    20461 gtgcaaattg ctaatgtgca aattgctaat gtgcaaattg cctaactaat aaatactaac
    20521 actaaataaa tactaaataa taataaatac taacaaacaa taagcatcat catcaacagc
    20581 aggaggagct atggacgaaa aaaagctttt tgaaaatttt caactaactt tcggaagaat
    20641 gatatcgcca tttgaaatag aagatattca aaagtggatt caccaggata atatgccgat
    20701 tgatgttgtt aaccttgctt taagagaagc ggtagaaaac aacaagatca attggaagta
    20761 tatcaacaaa attttggtgg agtggcataa agctggagat acgacgattg agaaggtcaa
    20821 agagaggttg cagagatttg aggatagcaa agaacaacga catgcaacta tctcaaatgt
    20881 tcctagctgg tcaaatccag actaccaagg cccgacatac gatgatttaa aagtaaatcc
    20941 aagcgaggtg tcagatggcg caggagattt ttgatggatt taatgcctta atcaataaaa
    21001 tgtatggcag acaatctagc atagagacct ttaaccgatt tgtcgagtat tgtcaaaaaa
    21061 ggagagagga aaacggggtt gagcctgtat taaatccgat caatcttttt gcattcggcg
    21121 ttggaatcac aacggaagaa gctaataaat taagaataaa acgctacaaa caggagaatg
    21181 gattatgaca aaacaatatc gagagacact tatctggcat cgggcaagtc acaaagagcg
    21241 tgagaagctg cttgatttcg ggctagttga taaatcacag tacatgacac tattacgcca
    21301 attgcgcaag aaatatgcga tttaggagga aatatgacac cagaacaagt ggaaaaagca
    21361 aaaatcagag ctaaacgaga acttgaaacg tttagcatct accttgacca ggcgattgtc
    21421 gaatacggaa gtacgctaag tccacaagaa gtctttttag cggcagggtt tgcctacctt
    21481 ggtgcaggtc agactgacat acatgcggcc atcgaggggt tatatgagca aatccaatga
    21541 ttttaatttt agcgatgact gggaaagcaa ctatttcgag gtccaagctt tgctagggca
    21601 agagatagac aagctccaaa acagggtcat agcgctaagc caggaaaaca atagattaaa
    21661 agcgaggaaa tgaaatggca agtgaaattg taacaattca aaaagatatc actgatatcg
    21721 ttaattcaaa aattagtatg cttcagaacg aaggtcttgt aatagcgcca aactatgctc
    21781 cagcaaatgc tttgaagtca gcattcttta aaattttaaa aaccaaagac agaaataaga
    21841 ggcctgctct tgaagcctgc acaaaggact caattgcgaa ctcgctcctt gaaatggtca
    21901 cccaaggatt atcacctgca aaaaatcaat gctattttat cgtttacggg aatgagctcc
    21961 aactgcaaag atcatatttc ggaacaatgg cagttttatt gcagcagaaa aaaattaaat
    22021 caattaagtc agaagttatt tatgaaggtg acgattttga gcttgaaatt gtagatggtg
    22081 aaaagaaatt caaaaagcat gatactcatt ggaaaaatca agacaatcca attgaagggg
    22141 cttattgcat tattgaggat atagatggta acactaagct aacactgatg acaaaaaaag
    22201 agattgataa agcgtggtct aagacaaaga ctggtggagg gacacaaaaa gaattccctc
    22261 aggaaatggc caaaaaaaca gttatcaaca gagctgctaa gttttttatc aatatcagtg
    22321 atgacagtga cattttggca gattctatta acaagaccac cgcagatgaa tatattgacg
    22381 atcgtcaagt aaaagatgta acggaaacac agtcacctgc acagacacta ctcgataaca
    22441 tgaagcatga cgaggaaatg agcaaaatcg aaacgatgca aaatgaacaa ttgatgcatg
    22501 atccagaaac aggagaaatc attgatgcag aggttgttga ggcggaccta aaggaatctg
    22561 atatggagga gccattctaa tgagcgaaaa tttaacactt tttgaaaatt taaatgacat
    22621 taaaccagcc gaacccgctg agctgagttt tgattttgag tttactccag ccgaaatcaa
    22681 aatcaaaggg aaagagaagc tcgaagagat tttagcagcc tacgctaaaa aatacgatgg
    22741 ctacacagtg acagccgaaa cctttgaaga cgatgcaaag gttagagcaa aactcaatac
    22801 tttgcagaaa gatattaata actctgtaaa aacaaaactc gcagaataca ataaccctct
    22861 tgatgatgtt aagcagtggg ttaactcaat tattgagcca attaaaaaaa ttacaaaaac
    22921 gattgatgag ggtgttaaac actttgaaga aatcgaacgt cagaagcgtg caaatacaat
    22981 caaagaaacc tttgaggctg ctattgctga aacaggtgct gatattgata tccgcttgtt
    23041 cgaatctaac tttgacgata tgtcggctaa aggatatttt atggctgaca acgtccgcgt
    23101 caataccgct accaaaaagg ccattaacaa attggttgct gaagaagtag caaaaaaaca
    23161 ggaacatgag caggcgctta tccaaatttc agaagctgct gccaaagcgg attttggacc
    23221 agctatctat atcaaacgat ttgaaaatgg cgcacaactg gcagatatct tacaagcaat
    23281 cgctgacgat aaactgcttg ctgacaaggt gcgcgaagaa gaaaaacgca aagcagaact
    23341 atctaagcga gtagaagaaa tgacagccct ggcacaacgt gaagggttgc aaccaggcaa
    23401 atatgtaaaa ttgcttgaag atggcaagtc tgctttagtc gtttttgaaa ctctgatgga
    23461 cgattctaaa aaaatgcagg ccaagatagc acaaaaaaac gcagaagcgc atcagcaaca
    23521 aatagaacag accgaatata tgtctgaggc ctcaaattcg ggggtaaacg agcttgaaac
    23581 agacaaggtg ataaataata tcatcaaaca agaaaatgcc ttagaagcca aaatagaacc
    23641 gaataagagc gtcacaaaat ggcaaggtga ttttaaaata actttcccgg attcagaaac
    23701 agctaaacta tttggcgggc aaggcggatt atacgaaaag catggcgtga ttgttgaaaa
    23761 attaggtgaa tgggtgaaga ttaatgacta aattaaccga agaaaattat tatcaagacc
    23821 gagaatggtt gtctaactca agatttaagg ctttccttga ttgtgaggct aaagctttag
    23881 ctgtcgaaaa caacgagtgg gaagatacca gagatgagac accgcttttg gttggtaact
    23941 accttcacag ctatttcgaa agtcctgaag ctcatgagaa attcaaagcc gagaatggag
    24001 ctaagatgat ttccagtcgt ggagttacaa aaggggaact caaaaaagag tacaaagtag
    24061 cgcaaaacat gattgaaacg ctagaaactg atgagatatt taatctcatg taccatggcc
    24121 aatctggtga taatgttttg aaagaaatga tcatatacgg ggaaatctta ggcataaaag
    24181 ttaaaggaaa agttgattca atcaatttaa caaaaggtta tttttgtgac ttaaaaacga
    24241 tgaaaagcat acacagcgac gaatggagta atgacttgcg taagcgtgta cctggtgtag
    24301 cagctaacat tatcgggttt aaataccata tccagatggg gctctatcaa gaattactca
    24361 gacagatgac tggaaaaacg cttcaaccgc taatcattgc aatcagtaaa gagaatgtac
    24421 cagataagga actcatcgaa cttggccaaa cgtggctaga tgaagggttg caactttttg
    24481 aaaacaatgt ggagcatgtg cacgaagtca tcattggtaa agctgaagct aagtcgtgtg
    24541 gacgttgtga ttattgtcga agtcagaaaa agcttaatag ggtggttgat ctcgatgatt
    24601 tgattgcagg aattttttag gagatcttat tgtattgcaa agtgatgctc ggcctttgca
    24661 gcaacaaata ttttccgagc gagaaaggaa aattgcaata tcgtcaagtt aacaggattg
    24721 atgatataaa gagttgctac actcgtcctt gctaatgctc acacacaatt ttagggcgag
    24781 tgtggatttt aaaaaggtga aaatatggaa caaatcaaaa ttacaggaac tgacacaata
    24841 ttaattttag atagagtaga tagggccttt gtcattgagg gtaatctagc tgaaagatgg
    24901 cgttttacta gcaagtttat aaagattgac gatgagctat cgctggacga ggacggcgaa
    24961 ttgtttgaga tagtttatga cttaatgcta gaagcaaaac ctcacaacgt gattaatcta
    25021 acatcatcat attttgctaa agaacataag aaagacacag atgaaatcat aaaagtattt
    25081 gcttttatcg aagataacaa gaagaatatt tttgaaaccc ttggcattcg cggggtgctt
    25141 gaatgagcaa tctagtatta tcgctagaca tctcaacatc tggtacaggt tgggccttat
    25201 ttaaaggctc agaccttatc cagagcggtg tcttaaaaca taagagcgac tcttattttg
    25261 aacgtggacg ctatatggct agcaaattaa ggttgatcca gtcacgagca ttaaaaaaat
    25321 acgattgctc ctttagcaca atcgcagtcg aaaaaaactc ggttatgggt ccaaatcaac
    25381 aatccatgct taaaatcggc attgtaactg gtatcatctt aggacgattg atag
//
LOCUS       DARYJX010000035        23058 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYJX010000035 DARYJX010000000
VERSION     DARYJX010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23058
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            102..1115
                     /gene="pfkA"
                     /locus_tag="TU257_001475"
     CDS             102..1115
                     /gene="pfkA"
                     /locus_tag="TU257_001475"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL0834480.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            1177..2679
                     /gene="pyk"
                     /locus_tag="TU257_001476"
     CDS             1177..2679
                     /gene="pyk"
                     /locus_tag="TU257_001476"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL0834481.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            2808..3365
                     /gene="lepB"
                     /locus_tag="TU257_001477"
     CDS             2808..3365
                     /gene="lepB"
                     /locus_tag="TU257_001477"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0834482.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            3542..5353
                     /gene="glmS"
                     /locus_tag="TU257_001478"
     CDS             3542..5353
                     /gene="glmS"
                     /locus_tag="TU257_001478"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL0834483.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            5537..5872
                     /locus_tag="TU257_001479"
     CDS             5537..5872
                     /locus_tag="TU257_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL0834484.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            5979..6620
                     /locus_tag="TU257_001480"
     CDS             5979..6620
                     /locus_tag="TU257_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0834485.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            6630..7259
                     /locus_tag="TU257_001481"
     CDS             6630..7259
                     /locus_tag="TU257_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0834486.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            7276..8112
                     /locus_tag="TU257_001482"
     CDS             7276..8112
                     /locus_tag="TU257_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0834487.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(8208..9446)
                     /locus_tag="TU257_001483"
     CDS             complement(8208..9446)
                     /locus_tag="TU257_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL0834488.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(9549..10883)
                     /locus_tag="TU257_001484"
     CDS             complement(9549..10883)
                     /locus_tag="TU257_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL0834489.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(11012..11098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            11363..13654
                     /gene="pcrA"
                     /locus_tag="TU257_001485"
     CDS             11363..13654
                     /gene="pcrA"
                     /locus_tag="TU257_001485"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL0834490.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
     gene            14067..14312
                     /locus_tag="TU257_001486"
     CDS             14067..14312
                     /locus_tag="TU257_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0834491.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            14360..14941
                     /gene="amaP"
                     /locus_tag="TU257_001487"
     CDS             14360..14941
                     /gene="amaP"
                     /locus_tag="TU257_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL0834492.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            14951..15139
                     /locus_tag="TU257_001488"
     CDS             14951..15139
                     /locus_tag="TU257_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL0834493.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            15152..15691
                     /locus_tag="TU257_001489"
     CDS             15152..15691
                     /locus_tag="TU257_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0834494.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            15729..15926
                     /locus_tag="TU257_001490"
     CDS             15729..15926
                     /locus_tag="TU257_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL0834495.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            15936..16424
                     /locus_tag="TU257_001491"
     CDS             15936..16424
                     /locus_tag="TU257_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0834496.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            16580..17221
                     /locus_tag="TU257_001492"
     CDS             16580..17221
                     /locus_tag="TU257_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0834497.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(17338..17886)
                     /locus_tag="TU257_001493"
     CDS             complement(17338..17886)
                     /locus_tag="TU257_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0834498.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            18009..18710
                     /locus_tag="TU257_001494"
     CDS             18009..18710
                     /locus_tag="TU257_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834499.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            18722..21361
                     /locus_tag="TU257_001495"
     CDS             18722..21361
                     /locus_tag="TU257_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL0834500.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            21437..22033
                     /locus_tag="TU257_001496"
     CDS             21437..22033
                     /locus_tag="TU257_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0834501.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            22043..23005
                     /locus_tag="TU257_001497"
     CDS             22043..23005
                     /locus_tag="TU257_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0834502.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         6708 a         4175 c         5391 g         6784 t
ORIGIN      
        1 gttgaaaacg gtttttcgat aaaaatagcg aattagtgaa gtaatttgca aacgaatgtg
       61 ctataataaa aacgttaaat taattaaagg agtaccaaaa aatgaaacgt attgctgttt
      121 taaccagtgg tggtgacgcc cctggtatga atgctgctat tcgtgcagtt gttcgtaaag
      181 caatttcaga aggaatggaa gtctatggta ttaaccgcgg ctatgctggt atggttgatg
      241 gtgatatctt tccactaggc tcaaaagagg ttggtgataa gatttctcgc ggcgggacct
      301 tcctttattc agctcgctac ccagagtttg ctcagcttga ggggcaattg gctggtattg
      361 agcagctaaa aaagcatggc attgaagggg tagttgtcat tggtggtgat ggttcttacc
      421 atggtgcgat gcgcttgact gagcatggct tccctgcagt aggtatccca gggacgattg
      481 ataacgatat tgctggaaca gactatacta tcggatttga cactgcggtc aatactgcgg
      541 tagaggctat tgataagctt cgcgatacct catcaagtca tggacggacc tttgttgttg
      601 aagtgatggg acgcaatgca ggtgatatcg cactttgggc aggtattgca agtggagcag
      661 atcaaatcat cgttcctgaa gaggaatttg acattcataa agtggtctca acaattaaag
      721 acgattttga aaatagagga aaaaatcacc atattatcgt tttagctgag ggtgttatga
      781 gtggcgaggc ctttgcgcag cagctaaaag aagctggaga tgaaagtgac cttcgtgtga
      841 caaaccttgg tcatatcctt cgcggtggct ctccaactgc gcgtgatcgt gtgattgcgt
      901 catggatggg agcgcacgct gttgagttgc tcaaggaagg caaaggtggc ttggctgttg
      961 gtattcataa tgaagagctt gttgaaagtc cgattcttgg aagtgcagag gacggtgcct
     1021 tgttcagcct tactgatgag ggtaacattg ttgttaataa cccgcacaag gctcgcttag
     1081 actatgctgc tttgaaccgt tcattagcac aataggataa gtaagatctg gtaatctttg
     1141 ttaatcaact aaaaaataag ggagtttcat aataaaatga ataaacgtgt aaaaattgtt
     1201 gcaacacttg gtcctgcggt tgaaattcgc ggtggtaaaa aatatggtga ggacggctat
     1261 tgggctggtc agttggacgt tgaacaatca gctaaaaaga tcgctgaatt gattgaagca
     1321 ggtgctaatg ttttccgctt taacttctca catggtgacc acaaagagca gggtgaccgt
     1381 atggctactg ttcgtcttgc tgaaaagctg gcacgtcaaa aggttggttt ccttttggat
     1441 acaaaaggac cagaaatgcg tacagaattg tttgctgacg atgccaaaga atatagctat
     1501 gtgactggtg agcgtattcg tgttgcgaca gcacaaggca ttcaatcaac tcgtgatatg
     1561 attgccttga atgtagctgg tgctcttgat atttatgatg aggttgaggt tggccacact
     1621 attcttattg acgatggaaa gcttggctta aaggttatcg agaaggacat tgcaaagcgt
     1681 gagttcatcg ttgaggttga aaatgatggc atcattgcaa agcaaaaggg tgttaatatc
     1741 cctaatacca agattccttt cccagcctta gcagaacgtg ataatgctga tattcgtttt
     1801 ggtcttgagc aaggtcttaa ctttattgct atttcatttg ttcgtactgc caaggacgtt
     1861 gaagaggttc gtgagatttg tcgtgaaaca ggcaatgagc atgttcaatt atttgctaaa
     1921 atcgaaaacc aacaaggtat tgataacctt gatgaaatca tcgaagctgc agatggtatc
     1981 atgattgctc gtggtgatat ggggattgag gtgccatttg aaatggttcc agtcttccaa
     2041 aaaatgatta tcaccaaggt aaatgcagca ggtaaagcag tcatcaccgc aactaacatg
     2101 cttgaaacaa tgactgaaaa accacgtgca actcgttcag aggtatctga cgttttcaac
     2161 gcggttattg acggtacaga tgcgacaatg ctttctggtg aatcagcaaa tggtaaatac
     2221 cctgttgaag cagttcgtac aatggctaca attgataaaa atgcacaaac tcttcttaat
     2281 gagtatggtc gtttagattc atctgccttc ccacgtacca ataaaactga cgtgattgct
     2341 tcagctgtta aagatgcaac acactcaatg gatatcaagc ttgttgtgac catcactgaa
     2401 acaggaaaca cagctcgtgc catttctaag ttccgtcctg atgctgacat cttggctgtg
     2461 acctttgatg aaaaggttca acgtgccttg atgattaact ggggtgtgat tccagtgctt
     2521 gctgaaagac cagcatcaac agatgatatg tttgaggtag cagagcgtgt agctcttgag
     2581 actggtttgg tgcaatcagg agataatatc gttattgttg caggtgtgcc agttggtaca
     2641 ggtggtacaa atacaatgcg tgttcgcact gtaaaataat agctttccat aagctttagc
     2701 tattttgctc tatcagataa tttaaggcaa acaatgatac ttaaaaattg tttgcttttt
     2761 ttattagtca tatcatgtta taatgagact atagactagg agttattatg gtaaagcgag
     2821 attttataag aaatatattg ttgttattga ttcttattgt gggagctgtc cttcttagaa
     2881 tatttgtttt ttcgacctat cgagtcacgt cagaggcttc aaatgcctat ttgaataagg
     2941 gcgatttaat caccattaag aaaaatattg agcctaaata taaggatttt gtggtttata
     3001 cggttgacaa aaaggattat gtgagccggg ttgtagcagt agcaggtgat cgtgttacct
     3061 atatggacga tattttttac ctgaacaata tggttgaatc ccaatcctac cttgagagta
     3121 tgaaggcaaa gtatctcaat catgccccta ttggtacgct ttatacggag gattttacga
     3181 tttcgacggt tacttctgga aaatacgata gcattcccaa ggggaaatac cttttgctaa
     3241 atgataacag aaaaaaccat catgatagcc gtcagtttgg cttaattgac gtgtcacaaa
     3301 ttaagggatt agtaacattt agagtgcttc ctttgaaaga ctttggattt gtagaggtag
     3361 agtagcttta aggctgctct attttgtttc tcaaaatatg actataccaa ttttcttgtt
     3421 gacaagattt ttctgaagtt atatactcta aatataacgt tttagtcggt ttatatctga
     3481 ctataccaat tatattgatc attaaagaaa gtagtaagct agcttactga ggtgttaagt
     3541 tatgtgtgga attgttggag ttgtaggtag tcgtaatgcg actgacatct tgatgcaggg
     3601 attggaaaaa ttagagtatc gtggttatga ttcagctggt atttttgtgt cagatggcag
     3661 gacgtccaat ttggtaaaat ctgttggacg cattgcagat ttacgctcta agattggcat
     3721 tgatgttgtt ggaacgaccg gtattggtca tacacgttgg gcaacgcatg gtcaagcaac
     3781 agaggaaaat gctcaccctc atacctctca gacaggtcgc tttgttcttg ttcataatgg
     3841 tgtgattgaa aattacctcc agatgaagga gcagtacctt gctggacaca cgtttaaagg
     3901 acaaacagac accgaaattg cagttcattt gattggagca tttgttgaag aaggctgttc
     3961 agtcttagag gcttttaaaa aggctttatc aatcattgaa ggctcctatg cctttgcttt
     4021 gattgataca gaggatatgg atacgatcta tgtcgctaag aataaatccc cattgctgat
     4081 tggccttggt gagggctata acatggtttg ttcagacgct atggccatga ttcgtgaaac
     4141 cagcgaattt atggaaatcc atgacaagga gctggttatc ctgacaaagg attcagcaag
     4201 ggtgacagat tatgctggca atccgattga tcgtcagtca tatacagcag agcttgatct
     4261 ttcagatatt ggcaagggga cctatccatt ttatatgcta aaggaaattg acgagcagcc
     4321 aacagtgatg cgtcgcttga tttcaaccta tgcagacgcc aagggacaga tgatgattga
     4381 tccagctatc ataaggtctg tccaagaggc tgatcgtatc tatattcttg cagctgggac
     4441 ctcttatcat gctggctttg cttctaagtc aatgctggag catttgactg atacacctgt
     4501 tgaattaggg gttgcttctg agtggggcta caatatgccg ctattgagca aaaagccaat
     4561 gtttatcctc ttgagccagt ccggtgagac agcagatagc cgtcaggttt tggtcaaggc
     4621 aaatgagatg gggattccaa gcctaacagt gacaaatgtt cctggctcaa ccctatcacg
     4681 tgaagcaacc tacactatgc tgctccatgc aggtccagaa attgcagttg catcaactaa
     4741 agcctacaca gcacaggtcg ctgcacttgc ctttctagct aaggcagttg gtgaggctaa
     4801 tggcaagaag gaagctatta gctttgattt ggttcatgaa ttgtcattgg tcgctcagtc
     4861 tattgaggcc accttatctg acaaggagct gattgctgag aaggtgcaga ccttattggc
     4921 aacaacacgc aatgcgtttt acattggtcg tggcaatgat tattatgttg ctatggaggc
     4981 tgcactaaaa ttaaaagaaa tttcatacat tcagtgtgaa gggtttgcag ctggtgagct
     5041 aaagcatggg actatttcac tgattgagga tggcacacct gttattggac ttatttcttc
     5101 aagtgagctg gttgctgcac atacacgtgg caatatccaa gaggtggctg cacgtggcgc
     5161 tcatgtgttg acagttgttg aggagggctt agagcgtgag ggagatgaca ttattattaa
     5221 taaggtgcac ccattcttag cgccgattgc tatggttatt ccgactcaat taattgctta
     5281 ctatgcttcc ttgcagcgtg gtttagatgt agataagcct cgtaatttag ccaaggctgt
     5341 tacagttgag taatagttgc ctgcttaaaa tgaggcagca gggtcctgaa gcctatttga
     5401 aacgagcttg acatgatgtt atgtcaggct cgttttttag tgcttgcctg gtcttatgat
     5461 aacgtattca tcttgtcaaa taagcatttc tgaagtaaaa tattaacgtt aagactaaga
     5521 agcttaggag agtaagatga cgttaccaaa ttgtttacaa tgcgattcag aatatgttta
     5581 tgaggacggg catttgctca tttgtccgat gtgttccttt gaatggacac gtggtgagga
     5641 ggagcctgag gaggaggggc ttgtcgtttt agatagtaat ggaactagat tagctgatgg
     5701 agacactgtt acgatcatta aggacctgaa ggtcaaggga gcgccgaagg atctcaagca
     5761 gggaactcgt gttaagcata ttcgtcttgt tgaaggtgat cacaatattg attgtaagat
     5821 tgatggcttt ggtgcaatga agctaaaatc agaattcgtc aagaagattt aataacaata
     5881 agcaaccaga tgactggttg tatttttata gaaaagtact tttcaatcca tcagaaaatt
     5941 tggtataatg gataaactat ttatatctag gagacaacat gacgtatatt atgcaggttt
     6001 tacccagctt gctggatggt gccttaatca ctttacaggt tttctttatt gtaattgtat
     6061 tatccattcc cttaggggct cttttagctt ttttgatgag ggttgacttt aagcccttgc
     6121 agtggctatt gacgctctat atttgggtca tgaggggaac acccttattg ttacagctca
     6181 tcttttttta ttatgttttg ccaagtgtgg gtgttacctt tgatcgtatg ccggcagcga
     6241 ttttggcttt taccttaaac tatgctgctt attttgccga gatttttcgt ggcgggatag
     6301 agactattcc aaatgggcaa tatgaggctg caaaggtgct gaagcttagt ccggtacaaa
     6361 ctgttcgcta tgttatcttg cctcaggtgt tcaagattgt tttaccaagt gttttcaatg
     6421 aggtgattaa cttagttaag gattcttcct tggtatatgt gttaggagta ggggatttgc
     6481 tattagcaag caagactgcg gcaaatagag atgcaacctt agcaccgatg tttattgcag
     6541 gtttgattta tttgctctta attggtttgg tcaccatttt atcgaagcag gttgaaaaaa
     6601 gatttaatta ttatcagtaa gggggtcata tgttagaact gaacaatatt tcaaagcgat
     6661 ttggtcacaa gcagatcttt gatggctttc atttgaccgt tgaagatggt gaggttttat
     6721 ctttggtagg gccatctggt ggtggcaaga ctactctgct ccgaatgctg gctggcttag
     6781 agcctattga ttcgggaaat attagctata atggcgagtc tgttcctatt gatcatttag
     6841 aaaaaagaag cctgcttggt tttgtttttc aggatttcca attgtttcca catttgacgg
     6901 tgctggataa tctcatcttg tctcctacca ttaccatggc tatgccaagg cctgatgcaa
     6961 agcaaaaggc tatggagctg ctggagcgcc taggtctcaa agagcatgca gctgcttatc
     7021 cttatgcgct atctggtggg caaaagcaaa gagttgcctt ggctagagcg atgatgattg
     7081 acccacagat tgtaggctat gatgagccga caagtgcctt agactctgaa ttacgtcagg
     7141 aggttgagaa attgattttg caaaatcgtg agatgggcat tacccagatt gttgtcaccc
     7201 atgatttgca gtttgctcag accatttctg atcgtatcat caagatcaat cctaaataga
     7261 agaagaggta gtgctatgac gttaaaaaag acccttctag tagccctatt tgctgctaca
     7321 gctacgcttt tagtagcttg tggcgctagt aataaacaga ctagctcaga tgcttgggat
     7381 tcctacaagc agaaaaagac gattacgctt ggctttgata atacttttgt gccaatgggc
     7441 tataaggacg agtcaggaaa aaataccggc tttgatattg agctagcaaa ggctgttttt
     7501 gaccaatatg gtatcaatgt taagtatcaa gccattaact gggatctcaa agaaactgag
     7561 ttgaacaatg gtaaaattga cctgatttgg aatggctatt ctgtgacaaa agagcgccaa
     7621 gctaaggtgg cctttacaga gccttatatg aaaaatgagc aagtcttagt gacgcaaaaa
     7681 tcatcgcaaa taagctcatt tgctgatatg aaaaataaga ccttaggtgc ccagtctggc
     7741 tcatctggct atgatgcctt tacgagtcat cctaaggtgc taaaggatct tgtcaaggga
     7801 aatgacgcta cccaatatga aacctttaca caagccttta tcgatttaaa aaacaagcgt
     7861 attgatggcc ttttgattga tagggtttat gccaattatt accttcagca agaaggtgag
     7921 ctagaccgct ataacattat cgcgagtgag tttgaaggtg aggattttgc agttggtgtc
     7981 cgaaaagcgg ataaaaccct acaaaaaaag attacacaag ccttaaaatc gctttatcag
     8041 gacggtacct tccaaaaaat ctctaaaaaa tggtttggtg aagatgtcgc aacagttcag
     8101 ttgaaatcat aagacgcaag caagacctaa tcagctcaga ggggttgaga ctagatacat
     8161 ttaaaagact taccttctaa aggcaagtct ttttatacgg cttattatta gctgatacgc
     8221 ttgatatgat agtgtttttt aattgctatg gagtttgtta ttggtgtgat ttgatgatat
     8281 atcaggtgcc aagcttcgtg tcgtctccag atactggtat gctgattgcc ctgtagctga
     8341 taggtgacta gcttggtgtt gtggctgatg gattgcatac aaaaggcttc aagctgattg
     8401 gaagaagaac gctgctgctc taaaaattgc ttggcattgt aagcttgtcc atcgcgatca
     8461 ataaaggtaa aggtcttggc aatgagctct tgataatctg ggatttgact tagcatgatt
     8521 ttctcgtttt tgtagagctt tttgtaaaca tattcacagt tgtcatcttt aggaagcttt
     8581 gcaggctcaa catgaatatc aatatcataa acagcaaatt gctcactcaa gagctgttcg
     8641 acctgctcgg ttatggcgtg actttcataa acagaaaggt cagggtgcat ctcaaggaca
     8701 atatctaaat agacattgct tccgtaagtg cggccgcgct gtgatttgac agcaatgatt
     8761 ttgggaattt tcaatatggc cttttcatat gctttgagct gcgtgctgtc aaagccatct
     8821 gataagctaa aggcgcttgc cataaaaata tcaaaggctg tttttagaat gaaaaaggta
     8881 atgataaggg cagccagcct atcaataata ggtagcttta aggaagcggc gataatagca
     8941 atagaggttc caatagaggt cacagcatca gaaagattat ctttagaggc tgcaaccaag
     9001 gcactggatc ttaccttttt tgataacgct ttattaaaag catatactcc aagcatcaca
     9061 agggctgaag cgatcccaac aatagcacct aatggatcga tagcagactg cttaccacta
     9121 atcatctgtt gaatagtttg caggagaacc tgaaagccaa caatgaacat gataaaggag
     9181 gttattaagc ttgaaaggtc ttcgattttc cagtggccaa agcggtgatt ggcgtctgct
     9241 ggctggctgg ccagatgaag tccgatgagc agagtgacat taccaacgat atcagacagg
     9301 ttgttgaagc catcggcaat caaggagctg gcatttaaaa gatagccagc aagaagcttt
     9361 gtgatgctaa gggccaaata ggtaacaatg ctaacaatgg gccctctttt tgctaaccga
     9421 aggttttcta ctggattgtt tggcataaaa actcctttgt aactgatgct ttcattatat
     9481 cataaaagct aagacaagct aaaagcctag agctatccta aatagggtat tccaggcttt
     9541 tcgatagctt atttggtgct ttggcgctta aaatatgccc ttgtctcaaa aatgacaaca
     9601 ggagataagg ctagtagggc gataagattt ggcagagcca tcaggccatt gacaatatct
     9661 gccagtatcc aaatcaactc cagcttaaga aagccaccaa gtcctaccat gataacaaag
     9721 atcaggcgaa aatagctgag gtgtgtcgtg ccaaataaaa agataaagca gcgctcacca
     9781 taatagctcc agccgagaat agtcgtaaaa gcaaaaagaa caagcgacag ggtcaaggca
     9841 taggtgccca tatgcccaaa gatagaagca aaggcagact gtgttaaggg tgctccctct
     9901 agtgcgctag tccactgacc agttaccaaa atggccagac cagtcagagt gcagatgatg
     9961 atcgtgtcaa taaaggttcc ggtcatagaa atcaggccct gttctactgg ctccttggtt
    10021 ttagcggcag cagcagcgat cggagcagag cctagtcctg attcgttaga aaaaacccca
    10081 cgtgcaatac ccttttgaat ggcgtcctta accaagcttc cggcaaagcc ccctatagct
    10141 gctgtagggg taatagcgga cttaaagata aggacaagca taggaagaag cttagtatag
    10201 tgaacagcaa taaccgttaa gcttgctcca atataaaaga tagccatgaa aggaacgact
    10261 gtttcagcca ccttggcaat agcttgaatg cctccaaaaa taatcatggc cacaacagca
    10321 gctagcaaga cactgattaa tggcgaagag atcccaaggc tatggtgtag ggatgaggta
    10381 atcgcattga cctgagcaaa tgtcccgatt ccaaacaaag ccactaaaat accagagaca
    10441 gcaaataagt tggctagagg cctccatttt tgccccatac catttaaaat gtagtacata
    10501 ggtccgcctg aaatctgacc attagcgtcc ttagtacggt atttaatggc taaaacgccc
    10561 tcggaatatt tggttgccat accaaagaag gcagcaaccc acatccaaaa aagtgcccca
    10621 ggtccaccag actttatagc ggttgcgaca ccaacaatat taccagtacc aactgtagca
    10681 gctagggctg ttgctagagc agcaaatgat gaaatatctc cttgcccctc attcttagca
    10741 aaaatgagcc taaaggcctt aggcaacttg atgacttgga gaaggctaag tctgctggtg
    10801 aggtaaatgc cagtaccaag cagcagtagc aacaagggtg ctccccaaac caaatcgtct
    10861 atccattttg cagcagctat catgcttaat tcctcaactc tcttaaccaa tgctgccaaa
    10921 agaaaaagcc acccctgcgg atagcctctg aagcatatga caaaacagca agcacaaaaa
    10981 atgctaagga agcatgatca tacggcttga tattttatct tctgtccttt tgcctgagag
    11041 attgagcagt cttgccttgc cccttcggcg cctaataggt ctctccagaa gcccgtccgt
    11101 caagcagtcc cgtccaacac ctgaacacct gagagtataa ctccttcggc gaaatccatt
    11161 cttctcctgc atgacatcat tcggtttatt aaattatgtc tatgataccc aaaaagccta
    11221 gtgatgtcaa caagcaattt aactgatggc taactccttg tttttatggt aacatcattg
    11281 tcctcttttt tctttttgac tgaaacatga tataatcgta aggttaataa aagtcactta
    11341 ttagacgata tgaggagaaa gcatgaatcc tttattagat ggaatgaatg ataaacaagc
    11401 agaggcagtt caaacgactg agggcccctt gttaattatg gctggtgccg gttctgggaa
    11461 aacgagggta ttaacccacc gcattgccta cttgattgat gaaaagtatg ttaatccctg
    11521 gaatattttg gcgattacct ttactaataa ggctgcgcgt gagatgcgag aaagggcatt
    11581 ggccttaagc ccagccacca aggatacctt gattgcgacc tttcactcaa tgtgtgttcg
    11641 tattttacgc cgtgaggcag atcatattgg ctacaatcgg aatttcacga ttgttgatcc
    11701 aggagaacag cggaccttaa tgaagagaat agtaaaagct ctaaatctgg atcctaagaa
    11761 atggagcgag cggtcgattt tagccaccat ttcaaatgct aaaaatgatc tcttagatga
    11821 aagagcctat gagctaggag cctctgattt gtatagccag acagttgccc gctgctacaa
    11881 ggcctatcag gaggagctca gacgaagtga ggctatggat tttgatgatt tgattatgat
    11941 gaccttacgc ctatttgatc aaaatcctga cgttctagcc tattatcagc agcgttatca
    12001 atatatacat gtcgatgaat accaagacac aaaccacgct caatatcagc tagtgactct
    12061 tttagcctca cgctttaaaa atatttgtgt tgtcggtgat gcagaccagt ccatttatgg
    12121 ctggcgtggt gctgatatgc aaaatatttt agattttgaa aaggattacc ctgatgcaag
    12181 ggtggttttg ctggaagaaa attatcgctc caccaagaaa atccttcagg cagctaacga
    12241 ggtgattcag cataatcgtc atcgtcgtcc gaaaaaattg tggactcaaa acgcagacgg
    12301 tgagcagatt gtttattata gggcaaatga tgagcgtgac gaggctgttt ttgttgcctc
    12361 aaccatcagc aatatgtgtc tagagctagg aaagagcttt aaagactttg ctgttttata
    12421 tcgtaccaat gctcagtccc gtacgattga agaagccttg ttaaaatcaa atattcccta
    12481 cacgatggtc ggaggaacca aattctacag cagaaaggaa attcgtgatg tgattgccta
    12541 tttgactgtg gttgctaatc cgtcagataa tctctccttt gaacgaattg tgaatgagcc
    12601 taaacgaggg gtagggccag gaaccctaga taagctccgc caatttgctt atgggcaagg
    12661 acagtcattg ttagaggccg cttcaagcct tgagcaatca ccgctaaaag gaaaggctgc
    12721 ccaagccatg ctggccttag cgagtctctt aagtgatttg agagctgatt tagaccagct
    12781 gagcattaca gccctggccg aggccttgct ggagaaaacc ggctatctgg atatgctgcg
    12841 cgtccaaaat accttagaaa gtcaagctag gattgaaaat attgaagaat tcctgtctgt
    12901 taccaaaagc tttgatgacc tatcagcaca gcagcaggag catgaagcag gtattgatcg
    12961 cttaggaaga tttctcaatg accttgcttt gattgctgat agtgatgatg gcaatgcaga
    13021 aaccgctgag gtaactttga tgactctgca tgcagctaag gggctagaat ttcctgttgt
    13081 ttttctcata ggtatggagg agggagtctt tcctttagcc cgagcagccg aggatcaaga
    13141 tgagctagaa gaagaaaggc gactagccta tgttggcatt accagagccg aggaatgctt
    13201 gtttttaacg aatgccaata cacgtaccct atttggtaaa agcagctata atcgcccaac
    13261 aaggttttta aaagagatgt cagagaacct tttaagcttc caaggcttgg caagacctgc
    13321 tcatgcttcc tttggtgtga cattttcgca gcagggtcaa cgacaatttg gcacaggaat
    13381 gagtctatca gaggctatcc agtccagaaa atcaatggca cagcctgcca gagcagcctc
    13441 aacatctaca ccgctgccct ttggaccgaa tgcagctact tcaaagcaag ccgttgattg
    13501 gcagattggt gatattgccc atcataaaaa atggggtgct ggaacggttt tagaggtcaa
    13561 gggatctggt aagaccatgg aattaaccat tagttttcct gatgtcggat taaaaaaact
    13621 ccttgccagc gttgctccta ttgaaaaaaa ataaaaggta cagcttatgg gcaatttgca
    13681 tagtcacttg gataagggct ttgcaattgc ggtttagttc tgcgatttaa gaaaagaagt
    13741 aagcaaggat tttatcagtt aaccacatac caagcttttg atggccttga tgccggagag
    13801 agcttggtat ttttttattt ttaaaaaaat cacaaaaaat gatttattct gagcataatc
    13861 cttgcaaatt aaaatgagaa gcgtataatg gcaatataaa ttaaataaca agtggtcact
    13921 tttgttaata gttgttttaa ggtatttgta gcgctttatt gttaaacata aatgtatcaa
    13981 aaaaataact agcaatttta tatttaattt atgtagtcac tttaaagagt gaacaaagta
    14041 gttttattga attgaggaga tttattatgg gaattatttg gacattaatt gtgggtgcac
    14101 ttatcggtgc tattgccggt gcgcttacta aaaaaggcgg atcaatgggc tggattgcca
    14161 atatcgctgc aggacttatt ggatcatacg ttggtcaagc tttgtttggc agctggggtc
    14221 taacattagc tggcatggca cttttcccat caatcattgg tgctgttatc gttgttatca
    14281 ttacttcttt tgtactaaat aaatcaaact aagggcattt ctatcattat agagatggtt
    14341 gagtaggaaa gaggttttta tgtcgaaatt tttaaaaatt agctatagtc tcattggctt
    14401 agtcctattg acggtctttg gtggcgtgat agccataact ggagattata ttaggctacc
    14461 tattggctat caatggcttc actgggatat gaattggctt cctaaattcc taaatccggc
    14521 cttatattac tattactttt gggcagctat cgctttattt ctaataacag tgctgatcct
    14581 tcttgtgatt atcttttatc cacgcaccta tactgagatt cagctggcta aggataaagg
    14641 aaccctgctt ttgaaagggt ctgctattga aggctatgta gcagctgcta ttaaagcagc
    14701 agggcttatg tcaagcccaa gagttaccgc taagctgtac aagcgtaaat ttaaggttaa
    14761 tgtcagtgga caattagctt ctcgcgtagc tgtcactgag cagctaaatg gcattaaaga
    14821 aggaattgag actggtttaa cagaattctt tggtattaat cgacctgtcc atttcaaggt
    14881 ttatgtcaag gatattgctg atgctaagca aaagcatagc tctaagagac gtgtagaata
    14941 ggagattatc atggcatttt atgaacggtt taaataccct attattggtg gtctgatagg
    15001 gctgatagct gctgtattac tgatgacctt tgggttattt aaaacactgc tggcaattat
    15061 tttcattatt ttaggagtat atggcggcct gtatgccaaa aagacaggta ttatcgatca
    15121 attgatcaaa cgtaactaaa ggagatttat catgactgaa acttacatta aaaacacaac
    15181 tcataaagaa ccaacttcag ctgttcgtgg cgaattgacc tatgatgaca aggtcattga
    15241 aaagatcgtt ggcttggctc ttgaaaacat tgatggccta ctaggtgtta atggtggctt
    15301 tttggccaat ctaaaagaca agcttgttaa tagtgattct gttcgtgatg gggttaatgt
    15361 tgaggttggt aaaaaagagg ttgctgttga tttagacatt gtagcagaat accaaaagca
    15421 tgttccaacc atttttgatg cgattaaatc tgtcgtagaa aatgaagtca agagaatgac
    15481 agatttagag gtgattgagg ttaatgttaa ggttgttgac attaaaacca aggagcaatt
    15541 tgaagctgat aaggtcagcc tacaggataa ggtgactgag gtagctcgct caacctctga
    15601 atttacaagc aagcaggtag acaatgttaa ggcatctgta ggtgcaggtg tagaaaaggt
    15661 tcaagagcaa actgagccac gcgttaagta agctaggctg tcaaacgata gaaatagagg
    15721 aaatcataat gtcagaagaa aaggtaaatg caaaattgga gcaagcaggc ggtaaaatca
    15781 aagaagcctt tggaaaggtg actggtgata aatccttaga aaccgaaggt aaggttgatc
    15841 aagcagccag caaaatcaaa gaagtagctg ctgatgctaa ggacgctgtc aagggctttg
    15901 ttaagggcct taagcaagat aaataaggag ttgtaatgaa agcaaaggac ataaaaagta
    15961 cgttgaccta cgatgataag gtcattgaaa aaatcgttgg acatgcttta gagaaggtca
    16021 gtggcttatt agcagtcaat ggtggctttt tctcaaatat caaaaataac ctagtgaata
    16081 gtgactctgt tcgtgatggg gtgtctgttg aggttggcag caaggaagtg gctgttgact
    16141 tagatattgt tgttgaatat ggtaaggata ttccagcaat tgttgagtct atcaaggcta
    16201 ttgtttttca aaatgtcgat agcatgacac atttgagggt cgttgaagta aatgtgaacg
    16261 ttgttgatat tagaaccaaa gaagagcatg aggctgctag cgtcactgtt caagacaggc
    16321 taacagacgc ggcctcagca acctctcaat ttgtagctga gcaagcagac aaggtaaaag
    16381 aaactgtctc taaaaccaca gataataacg agacagtaga ataaaacaca acaactaaaa
    16441 ctcctgttaa tgacatattg tgggctggtg tgatgaccag ctctttttat cagtgcttga
    16501 acaatgttat gctattgtat tctctgtgaa aatgtgattt aatgggaatg gtatcatttg
    16561 ttaaaaagga gtaattatca tgactagtaa taagagagag attactaatt ccaagtatca
    16621 aaagattgcc atttcagttg ctgaaaggat tgccaatggc gaatatgaag tgggagaaaa
    16681 gctaaagtct aggacaacca ttgcttcgac ctttaaagtt tcgcctgaaa ctgctagaaa
    16741 gggtctgaat attttagctg atctgaagat tttgacctta aagcatggga gtggcgccat
    16801 tgtcttgtct aaggaaaagg ctattgattt tctgaaccaa tacgaatcca cccattctat
    16861 cgctgtcatc aaagaaaata ttcgccataa tattcgtgag caggaaaagg caatggagca
    16921 tttaacagtg cttgttaatg agtttctgat gcaaagccaa tcaatcagca agcaataccc
    16981 gctggcacct tacgaaatta tttgtagtca ggattcagag cattttggcc aatccattgg
    17041 tgatttgaac atttggcatc aaacgggagc gacgattgta gctattgagc atgatggcca
    17101 attcattgtt tctcccggtc cttacgctgt tatcgaaaaa ggtgatcata tttactttgt
    17161 cggtaatgag gacgtgattt ctagaatgaa aacctttttt aatgttagaa agggtctgta
    17221 atcacaaaaa aacacagagc tgctttaagg tgatggtgat atcacgatga agtgtctctg
    17281 tgtttttgtg ttatcaggct aaggcttcta agtagcttat agctctgatt gaagccccta
    17341 gattactttt tcaaagccaa cagttttcag gataatagct gtcatgtcat cggttgtttc
    17401 ttgacagtca tgactaatcc agtagctaat cagactttca atactggcta gataaacctc
    17461 aagcgcgtag tgataaggga tctgatagtg cttggtgatg atttcttgaa agccatcaat
    17521 agtggtcaaa aattgataaa taaaatcctt gagtatttgt gaaaaattca aataactgga
    17581 gttagccata gcagcaataa agggaagatt atcaatgata taagcgaggg cttcctttag
    17641 aacgagtcta gtatctgtaa aaatatgagg gtcatttagg agctggtata aatcgtctaa
    17701 ggtgtcattt atgagatgag tcatcatatc atgtttatcc ctgtaatgca gataaaaggt
    17761 gcctctattg acaccagctt ttttggttaa gtcagaaacg gtaatggtct caaagctctt
    17821 ttctgtcaaa agactgacaa gtgcctgctt caaataggcc ttggttggtg tgtgtcttgt
    17881 tgtcatcgac tcatctcctt aagtcaacaa atgctgctta tctgttcttg ttaaagtctt
    17941 gaggacatta tataataagg ctagtataaa atcaacaagg tgttgatata aaggaggtga
    18001 catgatcagt gtcctatatt gaaatgaggt cctcttcaaa gacctaccag attggagaaa
    18061 caactgttaa ggctaatgat gaggtatcct ttgagattga aagaggggag cttgtgatca
    18121 ttttaggagc ctctggtgca ggcaagtcca cagtgcttaa tattttaggc ggcatggata
    18181 gcaatgacca aggtcaggtc ataatagacg gcaaggacat ctcgacctat agtaaaaagg
    18241 cattgaccag ctaccgtcgt tacgaggttg gctttgtttt tcaattttac aatctggtgc
    18301 caaatctgac agcaaaggaa aatgttgagc tggcggctga tattgtggca gatgcacttg
    18361 atccgactac tgtcttaaat gaggtggggc taggaggacg tttggagcat ttcccagcac
    18421 agctatcagg aggtgagcag caaagggtgt ctattgctcg tgccttggct aaaaatccta
    18481 agttgttgct ttgtgatgag ccaacagggg ctttagatta tcaaaccggc aagcaaattt
    18541 taagattgct tcaagatatg gcgcacgaca agggcaggac agttattgtg gtgacgcata
    18601 atactgctct agcgcctatt gctgatcggg tcatttatat gcatgacggt cgtgtgacca
    18661 agacagtgct taataagcag ccgcttgata ttgataggat aacgtattga gaggtgccta
    18721 gatgaaacaa aaaaccttat ggaaggatag ttttcgagca ataaaagcta gtaaggggcg
    18781 ttttttgtcc ttgctatttt taatggctct aggctccttt gccttggttg gcttaaaggt
    18841 ggctggtccc aatatggaaa aaactgctag tcactatcta gaggagcatc aggttatgga
    18901 ccttagtatc ctagcctcgc atggcttttc tgatagagat aagcaagaat tagcctctct
    18961 taaaaatgca agactagagt atgcgagctt tgttgatggt gcttttgatc accagaggaa
    19021 ggctattagg ctttattcta tgccacaaag cctatctcag gccagcttgg tcaagggaga
    19081 ttaccctagc aaggctagcg acattttgct atctgaagct ttatcaagcc gctatcggct
    19141 tgggcaaata atcacgataa gcctaaaaac aaagggattg ctaaagcata gatcctatcg
    19201 tgttgtcggc tttgctcatt ctccagaaat atggtccaaa acaaacttag gtgtttcctc
    19261 agcaggggat ggtaatctct atgcctatgc ctaccttcac cctagtgcct ttcagcaagg
    19321 gcacaatctc ttacgcattc ggtatgatga tttaagaggg ttgaatgcct tttcaactca
    19381 atacaatgaa cgattgctac aacaccaagc agagcttgat cagatcttgc aggacaatgg
    19441 tcaagagcgt tatgaagaaa tgctcaatga ccttaatcgc agcttgaaag atagtaaagt
    19501 taagctcgaa gagcaaagga ctgttcttaa ggcaagtgaa gaccagctgg ctttgctaag
    19561 tggtcatgcc ttagagcaag cgcagactca gctaaagcaa gggcaggaag agttagctaa
    19621 aaaagaagca agcttgctag agttagctga aaagcaaagg gcagcgatga tcaagccaac
    19681 ctatactagc tatagtcgct caacgctgcc aggtggtgag ggttatcaaa cctatgccac
    19741 ctcaacacag tccatatcgc atgttggaaa tatctttcct gttgttttgt atttggttgc
    19801 ggccttagtt acttttacaa caatggctcg ctatgttgac gaagaacgaa cgaactcagg
    19861 cttactaaag gcaataggct attctgattg ggatattacc aaaaaatttc tgctatatgg
    19921 tgccttagct gccttgttgg gcactggatt aggagtttta ggagggactt attttttatc
    19981 tcggctcatc tcagctatcc taacagatgc attgactatc ggctctactc agctttattt
    20041 ttattggagc tatagtgtgg ttgcagtgct tttagccttg ttatctgctg ttttgacagc
    20101 ttatatggtg gtgagacgtg agctttttct cagaccctca caactgttgc tgcctaagcc
    20161 tcctagtagc ggggcaagga tttggctgga gcatgtctcc tttatctggc ggcgtttatc
    20221 ctttacctat aaggttactt ttcgaaatat ctttcgatat aagcaaagaa tgctgatgac
    20281 agtaattgga gtagcaggtt ctgttgcgct cttattttcc ggcttgggca ttcaatcctc
    20341 acttgctaat agcctaagct atcaatttgg caagctgaca gcctatgaca tgctcgtggt
    20401 agaagctcca acagcagaag ctcatgatag gcaggagctg gcacaatatt tgaaggcaga
    20461 tcagattgct agtaagaaag agatttatta cgctaactta tcactaaaga taaaagactt
    20521 agacaacaag caaacagtgt cgttgatttc tagcgatcag agcactctat ctccctattt
    20581 tagcttgatt ggtgctgctg accgaaaaaa gctagacctt ccaagtactg gagtgcttat
    20641 ctcaaaaaag cttgctgact attatcaggc tcatgcagga gatcagcttg agcttgaagc
    20701 tagtaacggt aaacgctatc agttaagagt gagtcaggtt attgacatga ctgttggtca
    20761 ttacttgttc atgtctaaat cttattatca gcaggtattt cgggatatgg aggcttcacc
    20821 atcctatttg gtaacaacag caaaggctag tccatctgct gtaaaggacg tagctagtca
    20881 gctcttagca atgcctgcgg ttcaggctgt gtcacaacac agtagtattg ttgctactgt
    20941 gacagggatt gtggcgtctt tggatcaggt tatgacgctt ttagtacttc tatcagttct
    21001 actagccttg gtcattttgt atcatttgac caatatcaat attgctgaga gggttaggga
    21061 attatcaacg ataagagtct tgggctttta tgacaaggag gttaccttat acatttaccg
    21121 ggaaaccatg cttttgtctg ctgttggtat tttgatcggt ctctggggtg gcagctattt
    21181 gcacgcctat atcatgaagg tgattgctaa tgattctatg agctttggta ggacagttga
    21241 tgcttatgtt tacctagtac ctgttggggc tattgtgctt ttgttgattg tgcttggcta
    21301 tatggttagc taccggctaa gaaagattga tatgctagag gctctaaagt ctgttgatta
    21361 gggtaaaata gtacttgaaa atcgcttaat aatatgctag tattaaaata ctataattta
    21421 atagaaggat acttttatgg aagcgatgat agctgcctat ttggctgatc atagagaaaa
    21481 gataccactt ggtcaggttg ttgattgctt taaggggaag gctgtttctc gtaaggctga
    21541 ggctggtgaa tttggtttga ttaatctgtc tgatatggga cagctaggaa ttgactatca
    21601 tcaggttaga gcctttcata tggatagacg acaactattg cgctatatct tagaggatgg
    21661 agatgtcttg attgcctcaa aggggactgt tcagaaggtt tgtgtttttc ataagcaaga
    21721 aagggaaatg gtagcgtcct ctaatatcac agtgctgcgt cctcagaggg ttttgcgagg
    21781 ctattatatt aagttctttt tggagtctgc tattggtcaa gccttgttaa aggcggcgga
    21841 tcatggaaag gacgtgatta acctatcgac caaggcttta cttgatatcc ctgtaccagt
    21901 gattcctttg gttaagcagg attatttgat taatcaatat ttgcgaggcc tgcatgacta
    21961 tcaacggaaa gtaaacagag ctgagcagga gtggcagttt attcaaaatg aaattcaaaa
    22021 aggcttgggc tagaggtaaa atgtgagctt aattgaacga acaataaaaa tgctattagc
    22081 aacgatggct gcaatctttc ttgcctctca gctacagctg tcttatgcca tatcagcggg
    22141 aattattgcc ctgttaggtg tgctagacac tagaaaatct agcttaattg ttgctagaaa
    22201 gcgtctgctg tcttttttct tagcctttgc tgtggcggtt agtctatttg ccttatttgg
    22261 ctttggtctg ctttccattg gcttgtatct agcgctaacc attcctttgc tttatcagct
    22321 gaaaatagag gcaggtcttg ttcctatcac tgtcttggtg actcacctga tgtctgagca
    22381 gcgtattgat ttgtcaattc tttttaatga gctgttgctg tttttgattg ggacgggtct
    22441 tgcccttctt gttaacgggt atatggggtc tcaggagcat cgcctacgct tgtaccacca
    22501 aaagatagaa gatagcttaa aggctatctt gtaccgtttt gaatcctttt tgttagaagg
    22561 ccaaggacaa aacgagggac agatgattaa ggaattagag cttagcttag atgaggcgct
    22621 aaagctggtt tatcgcgaaa ggcacaatac cctcttttat cataccaatt atcaggtgca
    22681 ttattttgag atgagacgtc atcaaaatag attgttggcg caaatggcct taaatgtcac
    22741 tcagctaaca tctcaaagca gagaaagtct cctgctctcc catctttttc atgagacagc
    22801 tcgtcagctg agtgagaaga attctgcttt gacattgatt gatgatattg agcaattgct
    22861 tgaggtcttt aggcaaagag agctgcctca gactagagag gaatttgaaa gacgggcgat
    22921 tctgtttcag ctgttgcagg atttggagcg ctttattcta ctgaaggtag aattttatcg
    22981 tgattacaag gaagagcagg catagtagct gcttgctgct gtgattaaga gtctggaaaa
    23041 atcattttct aggctttt
//
LOCUS       DARYJX010000036        22722 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYJX010000036 DARYJX010000000
VERSION     DARYJX010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22722
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(72..2753)
                     /locus_tag="TU257_001498"
     CDS             complement(72..2753)
                     /locus_tag="TU257_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL0834503.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TU257_001499"
     CDS             complement(3101..3487)
                     /locus_tag="TU257_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL0834504.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TU257_001500"
     CDS             3568..4869
                     /locus_tag="TU257_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0834505.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TU257_001501"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TU257_001501"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL0834506.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TU257_001502"
     CDS             5903..7117
                     /locus_tag="TU257_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL0834507.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TU257_001503"
     CDS             7117..8352
                     /locus_tag="TU257_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0834508.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TU257_001504"
     CDS             complement(8561..9319)
                     /locus_tag="TU257_001504"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL0834509.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TU257_001505"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TU257_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL0834510.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            11732..14878
                     /locus_tag="TU257_001506"
     CDS             11732..14878
                     /locus_tag="TU257_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834511.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
     gene            complement(15172..16265)
                     /locus_tag="TU257_001507"
                     /pseudo
     CDS             complement(15172..16265)
                     /locus_tag="TU257_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(16249..16719)
                     /locus_tag="TU257_001508"
     CDS             complement(16249..16719)
                     /locus_tag="TU257_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0834512.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            complement(17032..17355)
                     /locus_tag="TU257_001509"
     CDS             complement(17032..17355)
                     /locus_tag="TU257_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834513.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            complement(17356..17748)
                     /locus_tag="TU257_001510"
     CDS             complement(17356..17748)
                     /locus_tag="TU257_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0834514.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            complement(18011..18424)
                     /locus_tag="TU257_001511"
     CDS             complement(18011..18424)
                     /locus_tag="TU257_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834515.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            complement(18417..18845)
                     /locus_tag="TU257_001512"
     CDS             complement(18417..18845)
                     /locus_tag="TU257_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834516.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            complement(18842..19246)
                     /locus_tag="TU257_001513"
     CDS             complement(18842..19246)
                     /locus_tag="TU257_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834517.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            complement(19505..19927)
                     /locus_tag="TU257_001514"
     CDS             complement(19505..19927)
                     /locus_tag="TU257_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834518.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            complement(19909..20538)
                     /locus_tag="TU257_001515"
     CDS             complement(19909..20538)
                     /locus_tag="TU257_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834519.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            complement(20797..21120)
                     /locus_tag="TU257_001516"
     CDS             complement(20797..21120)
                     /locus_tag="TU257_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834520.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            complement(21121..21540)
                     /locus_tag="TU257_001517"
     CDS             complement(21121..21540)
                     /locus_tag="TU257_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0834521.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            complement(21976..22563)
                     /locus_tag="TU257_001518"
     CDS             complement(21976..22563)
                     /locus_tag="TU257_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834522.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNGFPEDSVSLSFAGNKCI
                     IEEIHRDNRIRLMETTSEYHAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
BASE COUNT         6838 a         5012 c         4152 g         6720 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttattatatt ttgttaattt tataatctat ttaactattt taaaaattta
    11401 cttatttaaa tcacaaaaca ctgttataat aacgttttaa ggctatcaat gattaagaat
    11461 tttccaaacc tatttatcat ttctaggatt aaagaaaata tatattgaca tattctgatt
    11521 ttttaatatt atggaataag agagacaaaa tagtcaaaaa ggagggatag gatttttagc
    11581 accgtaacaa tatcatcacc acagcatcaa gagctaagga gggtaaatag tctttctatt
    11641 ttatagtatt tgcgagtata gttttaaggc tagctattct tttcccagag ttttgaatca
    11701 ctttatttta ttgtaaaagg actttataac gatgaaacta aagaaaataa tagcactagc
    11761 atgtgttgga atattaacat tacatcagct ctctccagca attgtttatg caactactga
    11821 tacttctgat ggaatagccg ctacagttaa tgcaggtgat acagctgctc cttctgccga
    11881 ggctaagcta tcacaactga tgactgatac ccaagcctta tttacagata actcctgcag
    11941 taagctggca agtggtgtca cacaagaaaa aatagatacc ttaaagcaaa aggcgactga
    12001 ctcaacagag cctgaaaaag agcaaatcct aggtctacta gataaggcag ctagcctatt
    12061 acagcagttt accctacaag ggttaggcaa tggtgtcttt gctcaacttt acttctatgc
    12121 tgatggcagc tacactgcaa gtttggtcac taaaaggggc cagcctcact cttatttctc
    12181 tactaattac gctacgataa ccattcttaa taacaagaag gaaaccgtct attcaaaaga
    12241 atacgccggc aatgtttctc aggtagcaca aacagaagag cttgagctaa aagaaggcta
    12301 ttacctcatc atcaataaac aggagcctaa ccgcttctac actaaccata atgacgctct
    12361 aaagcaaaac aataccaacc cttatactta tgtggtgaga gatgggcagc ttgagcgtat
    12421 tgatgatagt aatagaacgc tgcgcttcct tggcttaggc aatgcagagt atgcaacctt
    12481 aagggttgat tacaatgcct ctaccctaac cctcaaaacc aagcagacca agccacatgt
    12541 ttacttcagt ggatcttatg aaaagcttga ggtgctggat acagaaaatc aagtaatcta
    12601 cacaaaggac tttattggaa ctcaagtcct cgaagctaaa acagagacta ttccttttaa
    12661 agtaggctac aagatccgct tgacaggtag tgagcaccat accagagtga aattctacga
    12721 tgattatgcg gtagaagcgc cattaacact ctctaaaaat caagcaacct taaagcttct
    12781 tgaccactca ctagagctaa tgaggtctaa aacaggctca gagcttgagt ctgaggtact
    12841 gactctattt acagatgagt ctacaagtaa gctagcaagt ggtgtcacac aagaaaaaat
    12901 agatgctctt aggaaaaagg cgactgactc aacagagcct gaaaaagagc aaatcctaag
    12961 tttacttgat aaggcagcta gcctgctaca gcaatttact ctacaagggc taggaaatgg
    13021 tatatttgct cagctctact tctatgctga cggcagttac actgcaagct tagtcactaa
    13081 aaaaggacag cctcactctt acatcgctaa caattacgct accctaacca ttctcaatga
    13141 gaaaaaagaa accgtttatg ctaaggaata cgtgggtaat gtttcccaaa cagctaaaac
    13201 agaaagcctt actctcaagg aaggctatta cctagtcatc actaagcagg agcctaaccg
    13261 cttctacact aaccacaatg acgctctaaa gcaaaacaat accaaccctt acacttatgt
    13321 ggtgagaaac gggcagcttg agcgtattga tgatagtaat agaacgctgc gcttccttgg
    13381 cttaggcaat gcagaatacg caaccttaaa ggttgactac aatgcctcta ccttaactct
    13441 caaaaccaaa aaggctaagc cacatgttta cttcagtggg acttacgaaa agcttgaggt
    13501 cttagaccta aaagacaagg ttgtctacac acaagacttt attggaaacc aagctctaac
    13561 agccaaaaca gagactattc ccttcaaggt gggctacaag atccgcctaa ctggtagtga
    13621 gcaccatact agagtcaaag cctatgatga agaaaacaag gctgtttctc ttagcctccc
    13681 taaaaataag gcagagattc gaatcaccaa gggtggtttg gcttctgtat ttgcactaga
    13741 ggctaaagct actaatacac tcgtacaagc cgttgaaaaa agactaacca aggaaaaaat
    13801 cgaggacttc aagaagcaag acgacaagca taaagccttt attgattggt tgctcaaaga
    13861 taatgaagca atgcaattat atcttggtgc aggctatgcc cattctgcag cacagggtgg
    13921 catgtcatca taccaattca aaaacaccta taacctcacc aatgagctag aagcattgga
    13981 attgtggttt aagatttggg ataaatacga aacctcacat caaggtattc agctcaaaat
    14041 ggccattgcg gttgccttgg aatttaacaa gcctgtaggt gcttggtaca atgaaagccg
    14101 caagattgat ccacttgaaa gatttgcaac ctttgcagag gctgagcagg gcaatatcct
    14161 atttgaagat ttttacagct taactgttga gcaaatccga aatgtcgtca atgctaaaat
    14221 tactgatgag gacatgaaat ggttaagaca atacgttgaa accaataagc ctgctatgat
    14281 taaccgtaat gatattacta agggctattc actgatcagc tatgtcatga ccaacccaga
    14341 aacaggtgtg agcgtccaaa gctctggctt ttacggacca aatccaacca tcaaggaagt
    14401 catcaaatat ggtggtgtct gcggtgctat gtctaaatta agtagtgtgc tagcacaggc
    14461 ttatggtgta ccagcctttc ctattggaca accaggtcac tgtgcttata tctacttaaa
    14521 tgctgaccat acctatcagc tcggctatga tgtctcaggc tggacaggct gtggtaacta
    14581 caacacaaca cttccttatg tccaaattca taacgtctac tctcttaata tagacgctta
    14641 taatgcctca gaatatgaac gatataaggc tgaagcagct actgacaagg agactaagct
    14701 taatcattta gatgctgctc taaaggcaga gccattaaac tataaagcat ggaatgacaa
    14761 gctagcattg gtagcctcag accaaacagc atatcaaagc actctaaatg acatgaagtc
    14821 tgcattgaag gattatccag ttattatcaa taatttagaa aaagatacta aacagtaagc
    14881 taagcccttg ggcttaaaag aaggctagct aaaactatac ttacaaatac tataaaatat
    14941 aagagtctca gcttgaagga catgctcaat tgagagagct gcttcaagct tttttgattg
    15001 cagcaaagca aaaagcccca gaagcagtga tcaaacactg acctccaaga gccttttgac
    15061 gtcttttgac ctaagctgga gcttttttaa gcatcgattt acttaatcta atctctttta
    15121 ggctttttat cctttgcctg atgcgcttga ttagcagcac aagcttttta tttacttggt
    15181 tagctgatga tagggctgaa tggcaacaga ctgaccaata tttgaggcat aaatccaatc
    15241 agctgttttt aaggaggcaa actgctcagc cttgccggtt aaaataatgc cagcaaactt
    15301 agctgttttg acattgcgat tgttttttag aaataaggcc acatcctcct gctcacttaa
    15361 atgagatcca ttagcgccgc cataggtact attaatccaa tgattgtcag ctgcctcttg
    15421 tagatagtgc ctgaaggtat cataggaatt ttgcagagcc accgttggac tgactggctt
    15481 atcgtaagca gcattaagct tagacaaatc agcctcgctg tcctttttta ggatatcgtt
    15541 tattttttta tctaactgct tttgctcctt gtacgtcata ttagccttcc agtttggctt
    15601 aaagccatat aaattagcag ggaaaagccc tgaggtgtca tagctgcttt ctgtgccaat
    15661 ccagatccaa ttcagcttta gctggtctgg aaccagcttg actatgtccg ataataaata
    15721 aggcttatca aaggtaatgg ctacctcaat cgcctgtcct gacatgtcag caataaagtc
    15781 taggtcctgc gttggcttgt catagttgct ttctgtgatc ttggccttag tgttgaagaa
    15841 gcgaggcatt ttataatgtg tacctcttgt gtaggttgac cgtccatcat cacctgaaac
    15901 aaggtattca ttggtatagt ccatctctct ctgggtaaag gcaaggaata aggagctcta
    15961 tagggctcaa acggtaccga aatcccagca atatccttgg tccgctcaga atgaagctca
    16021 ccagtaaact gcgaattggc attgtaaaag aagctattaa catcaatatt gggataagca
    16081 atttgtatac gattgttgta ataagccatt aaatactgac cgttcatgct tgtcaatcga
    16141 tttaatccca tatagcccag tacaagagct actaaggcta agccagcact cagcactaca
    16201 tatttaaggg tcagcctcct tttatggcgc ttagcaatgg cttcaaaatc agttgaaatc
    16261 gtcataggta taacctgctt tctttagttt ttctttaagg catcgtcttc cccgcatcaa
    16321 gttgaccttg acgctgctaa ctgaccaatg gagcagagac gccatttcct tgactgatag
    16381 gtcctgaaag taataaaacg acaagaccca gcggtatttt tctggcaatt cattgactgc
    16441 tgtataaagc ggctcataat tggggtggtc aaattcaaca accctttctt gatgaaaaaa
    16501 atccctttgg agaatatcca agtaagcctt atcccgccta tatcggtcaa tgtattttct
    16561 aacagcaacc cgatacatcc aggcacgtat tttttcagga ggcagagcaa ggtcactctc
    16621 aagcattttt aacaaaacgt cttgactaat atcacgcgct agctccttag caacacctga
    16681 tctcactagg taggcaataa tttccttaga ataagccact agctctcttt cataagcatc
    16741 tagcctgata attctcccct cccttcttca cctatataac gaacgactgc ttcatttggt
    16801 tacaaaaaaa tccccaaatg gagattttta gctctatcat ttctgtagtg ggtaagtcca
    16861 ccatggagat tatagggctt ttttatatga caaaattcaa attaagtgca acacttttcc
    16921 ataaaagagt tcataagata gtttccagtc gggacatttc ctaggaccat tatttcattt
    16981 atcttcccac tctaattgac tacatgccat gtatattctc ctttacttgt attaattttt
    17041 tgaccacaaa ggagaatcgt aatttacagg catgccctct tccacatagt acctgttgat
    17101 ttggatatct aaccgaagtt tttcaagaaa tttttcttta gcctcttgaa atgtttcaaa
    17161 tgttaatttc ttattataac tagctctatc catagttgca tacacaacat ataagccttg
    17221 actattatca tattcaatga cagtttccca ttctcctggt ctctctttag aaaaaatgga
    17281 ataccttaga ctatcataac ctaattgatg gactgcttct aatagttctg ccttttgatg
    17341 atctaaattt ttcatctact ttatctcctt aattaaaccc aatttttcat accaacttac
    17401 agaagttcct aactttattt ggatacctcc accagagcca aagacaagat caatcattcc
    17461 tttttgtgga gttgctatgt ctaccagtga aaaatcaaat ctattcatta atagatttaa
    17521 ctcttttttt ctactatcag ataaattatg gtaacccttt tcaacatttt ccatattaat
    17581 atccttaaga accttatatt gatgataatt ttgatagtcc tctgggtatg gtaagcctcg
    17641 cttgttaaat ggtataacct tacggtcaac gattggactt gtgaatgttc ctccagattc
    17701 tccatatcta tcaagtaaat cacctgtttt taggaaagct ggagtcatga taggccttcc
    17761 ctttacatca agactaaagc cattatagtt tggccaatta atagaaccat cagccttaag
    17821 gtaatttcta tatcggacag gaattggtgt tccggtagct ttatcaatgt cattggacag
    17881 ataagcatat tttccatctg gcatggtgat tctttctgca aaataccttc cctttaactg
    17941 gtattctctt cgaaggtatt ggtaaatact gttcttcact catctatatg ccctccagaa
    18001 gtgattagaa ttattgttcc tcttcacatt tttgatccag ataatccttc aaaacacgca
    18061 taacatattc aacagatttc agatccagtc ctaagcacca tcttatattt tcacttacat
    18121 ttttatcaga aattaaataa gaaagtgata caattttttg aaatgactgc tccggatatt
    18181 taggattagg taaacttaca ctgaataaac caccttctcc agcttggaat tgaatattct
    18241 taccagtatc ataaattccc atcatcattt cacaattttt atatgtaaag acaaagttaa
    18301 aattctcatc ttctccttca tgtatagaaa tttcatcaag gttggctgaa aaaatagtcc
    18361 ataaagcctg tttaacgttc ttataaccta agctttcttt tattgataaa tattgctcac
    18421 tcatttttca ataaaacctt tgcttcgtct gaatctaaat aatcttttag aatggccaac
    18481 gctatttcga gacgatgctc gtatcttcca aaagcatagt caactgcttc tattttttcg
    18541 gtgtctgtta aaagactttc taaggttacc ctatcaagaa aggatctatc aggatacttt
    18601 ggattaggaa gtgaaatcat caattgtcct ccttctccat attcaaattg tctattctta
    18661 ccagttgatg taatccagat tatgatttct ttattgttat aatttaaatg aaaaccaaaa
    18721 ttttcaaatt ctccttcaat aattgtaaac ttatccaaat ctattgaaaa aacattcatt
    18781 aaagctattt ttaagttacg atatcctaag ctttccttta ctggtaaata ctgttcttca
    18841 ctcatttata tgccctccaa aacctttcaa atttttcaat attatatcca ttttctgcta
    18901 aaatctgaat ttctttagca taagacttcc cgataccact aacatctgcg attgattgag
    18961 cagtatatgg attagacgtt aatataaatg tttttctttt ctcaatttgt tttatcaaaa
    19021 attcacgatt aaccctttga gctagcttag aatccactct cgacatcgca ttccaaccat
    19081 cacttccggc atcaaagtaa gttaacttat tttgatgtgc aatttgttca tacgaagtaa
    19141 cgctgtttgc ttcgtaatat cccagcaaag ctgttttggt ttttgcattg tgggtggtca
    19201 gctcggttaa tttggccacg tcagcttctg tatagttctt actcatactt tctgcgtaag
    19261 ccacaatgcg agactcatca aaccgaacct ttgtgtctag taccttttca gaaagggtta
    19321 ttttcgctga tttcgtcact ttagctgcta tcggctcatt caagctgaac cttctggcgg
    19381 cgcttggaga cgcttggcat tggcttcaag gtgacgagct actccctgat aagctgtcgc
    19441 aggctaatta ttaagaacat gctttaaaat agcagagcta atctcggctc cgctatctta
    19501 aacattattt caaaggactg acataatcat ctggcagctt tcccttccaa tctatccact
    19561 gttgttcagc gattggcact aattttgata attcttcttc tgagaacaga gacacactag
    19621 tagggtctgc aatcagcgca gttggtgtgt caataacaaa ttttctatga ctttgcttct
    19681 tttcctcttc tgttggtggc caattaccat cttgtagctt tgaatgaaca tctccaagac
    19741 tacgttctcc actttccaac aattcaaata agtcatacgg taactcatat actactcgtt
    19801 gaacagcaat gccaccttct tcggcaacaa agtaatattt cccttgatgc ttccacaccc
    19861 tttgaccata gccctttacc tcctcatatt gactaacatc ttcccactct aattgactgc
    19921 gtgccatgtg tgatctcctt tctttgtact gataccttgc ataactccct ctggtatatt
    19981 ccccggataa gtacgacctc caggacgcca ccagctattt gccccttttt cattaccact
    20041 tggtattgaa acaccttttt gtgaaacaac ttctggtgaa acatctaagc gatagagggg
    20101 accatcttct aaataccctt catcaaagcc taagagtgtc tcataaagac ggttatttcc
    20161 ctttcctatc tcctggataa tatccgcgtc cttggtactt aaccaaaaac tattgcctaa
    20221 atcgtcacca actaaaccgt cttggtaatc tacattgggc ttaaatttct gaaatctagt
    20281 tgcaccgtta tcaaattgtt ttctatgaaa tccaatataa tctggactgt agactttctc
    20341 cacatttgga cgatcaccct tggatattgc caatatacta tctgatgttt ttcccggaag
    20401 atactctatc ttcggtgcct tctcagatat ttctagaatc cttactcgat ctgacggact
    20461 aagtccagcc tttgcgtatt tgtgccattg aatatagcgc tgactatcct caggactcat
    20521 gcctgcaagg gttgtcatga atttttctct tgctacataa ttcttaaacc ttgagctttc
    20581 tcttgccagt ctgctgttct caaggttctt caaaagctgc tggcggttgt gggtcggttt
    20641 cgtcacccta gttgctattg gctcattcaa gctgaacctt ctagcggcgc ttgaggcggc
    20701 aagtcctcct aggatattcc caactaatgt tgctctttgg gcgtcttgct cgctgcctcc
    20761 taaaagcttg gtgccatggc atacaataca tgaaactcat tcattccata gtggtgaggg
    20821 atattctgta ggttcaccta actgcttttt taaccgatta gattctataa ctaattctaa
    20881 ttttttaagc aattcatgct tggcatcatc aaatttacga tattccctgc tatgaccaat
    20941 gatatatgat cgctcatctc ttccttcaac atagaatttt ccattttttt gataaagatg
    21001 aaatgcccaa ggaagtcgct tttcttcatc aaataaaaca taatgtaaac tctcaaaacc
    21061 tcgattttta attgcttctt caatatcttt tttccaattc aatatatttg tattatccat
    21121 ctagttaatc tcctttaata aacccatttt cttgtaaata ccaacacctg tcggaaattt
    21181 aatctgaatt cctccacctt gcccaaatac tttggtaatc tcacccttct gaatattagc
    21241 taaatcatca aaggaaagat tccatttttt catttctaca gatatttgtt ttcttataat
    21301 ctcttcagat tgataatacg cattaacaat atttttcttc gtcaaatcca ttactaattc
    21361 gtacttataa tagtcttgat atccttctgg gtagggtaat ccacgtttat taaatggtaa
    21421 tgtcacccca ttttctatcg gactggtaaa tcgaccacta cttgatccat atcgatcaat
    21481 gatttgacct gctttgagag tgacctgctc cgttatagga ttacctaaat tatccaccat
    21541 aaagccatcg gcatttggcc atttaatatg gcctgcttcg tcaacaaaag ctctagagcg
    21601 aaccggaatt tgcttgcctt caaaatagtc agatgaaaga taacctatct ttccatttga
    21661 aatagtggtt ctttctgcaa aataccttcc ctttaaccgg tattctcttc gaagataatc
    21721 atcaaacctc gagctttctc ttgccagcct gctgttctca aggttcttca aaagctgccg
    21781 gcggctgtag gtcggtttcg tcaccctagc tgctattggc tcattcaagc tgaaccgtct
    21841 ggcgacgctt gaggcggcga atcctcctag gatattgcct actaatgtag ctcgctgagc
    21901 atcttgttcg ctgcctcctg ccatgactgg gcatctgaac tcaaaatgcc atatggtatt
    21961 tcaatagttc ttttattaat tccttcctat caaataatat tctacaaact gattaaattc
    22021 taacttacaa tcaggcaagt catgtagtgc tctagcatat aattcttttg ctctctcaag
    22081 ttttttagtg taattaaata aaacaatgta agcacgtaat gaacttaaat cagttagaat
    22141 ttgcacatca ttaaatatta aactataggc attattttct tttacaaggg ttaatttatc
    22201 tttttccaca gaccctaatg aaaaaagagt aggatccaat ttttctgaga gcaactgctc
    22261 agctgctata atatttcctt cctgtatata ctctttgatt tctcttgtaa tcttgatatt
    22321 tttactagta ttaaagatct ggtccaaaat tgcaacacaa tataaaatag catgatattc
    22381 tgaagttgtt tccattaacc tgattctatt atctctatga atttcttcaa tgatacattt
    22441 attacccgca aatgataaag atacactatc ttcaggaaag ccattataaa atattatttc
    22501 attttctatt ttatttgcgc tcagcctaac atcaaaaaga atgtttttta ttttatcaat
    22561 caattctaat ttctcctttc ttcaccaaat cagttatgtc atctaaaaaa ccatatccat
    22621 tagctcttga atactatatt tatcaactcc attaggttta tacttcacaa attgatctga
    22681 aacctcacca gcatatactc aaataaacat agtatcctct ga
//
LOCUS       DARYJX010000037        22677 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYJX010000037 DARYJX010000000
VERSION     DARYJX010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22677
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(92..562)
                     /locus_tag="TU257_001519"
     CDS             complement(92..562)
                     /locus_tag="TU257_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0834523.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            783..1633
                     /locus_tag="TU257_001520"
                     /pseudo
     CDS             783..1633
                     /locus_tag="TU257_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1969..2259
                     /locus_tag="TU257_001521"
     CDS             1969..2259
                     /locus_tag="TU257_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL0834524.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2273..3412
                     /locus_tag="TU257_001522"
     CDS             2273..3412
                     /locus_tag="TU257_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834525.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3415..3891
                     /locus_tag="TU257_001523"
     CDS             3415..3891
                     /locus_tag="TU257_001523"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL0834526.1"
                     /translation="MRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDFTL
                     EVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGLLE
                     IPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG"
     gene            3888..4475
                     /locus_tag="TU257_001524"
     CDS             3888..4475
                     /locus_tag="TU257_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0834527.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4472..4954
                     /locus_tag="TU257_001525"
     CDS             4472..4954
                     /locus_tag="TU257_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834528.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4979..5494
                     /locus_tag="TU257_001526"
     CDS             4979..5494
                     /locus_tag="TU257_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834529.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6128..7762
                     /locus_tag="TU257_001527"
     CDS             6128..7762
                     /locus_tag="TU257_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834530.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7903..8796)
                     /locus_tag="TU257_001528"
     CDS             complement(7903..8796)
                     /locus_tag="TU257_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0834531.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8780..8971)
                     /locus_tag="TU257_001529"
     CDS             complement(8780..8971)
                     /locus_tag="TU257_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834532.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9206..10960
                     /locus_tag="TU257_001530"
     CDS             9206..10960
                     /locus_tag="TU257_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0834533.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11101..11481
                     /locus_tag="TU257_001531"
     CDS             11101..11481
                     /locus_tag="TU257_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL0834534.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11519..13852
                     /locus_tag="TU257_001532"
     CDS             11519..13852
                     /locus_tag="TU257_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0834535.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13901..14053
                     /gene="rpmG"
                     /locus_tag="TU257_001533"
     CDS             13901..14053
                     /gene="rpmG"
                     /locus_tag="TU257_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0834536.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14065..14241
                     /gene="secE"
                     /locus_tag="TU257_001534"
     CDS             14065..14241
                     /gene="secE"
                     /locus_tag="TU257_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL0834537.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14632..15177
                     /gene="nusG"
                     /locus_tag="TU257_001535"
     CDS             14632..15177
                     /gene="nusG"
                     /locus_tag="TU257_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL0834538.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            16220..17737
                     /locus_tag="TU257_001536"
     CDS             16220..17737
                     /locus_tag="TU257_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0834539.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            18019..18882
                     /locus_tag="TU257_001537"
                     /pseudo
     CDS             18019..18882
                     /locus_tag="TU257_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            19471..21972
                     /locus_tag="TU257_001538"
     CDS             19471..21972
                     /locus_tag="TU257_001538"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL0834540.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            22159..22650
                     /locus_tag="TU257_001539"
     CDS             22159..22650
                     /locus_tag="TU257_001539"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834541.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
BASE COUNT         6663 a         4134 c         5040 g         6840 t
ORIGIN      
        1 tcaaggcttt tgcaggagat ttatgaaaaa gaaaaattta ggatagtgta agtataagct
       61 agtttcctta agaaaagctt aactgaagca attaatcgta gagatgggtg attgttttga
      121 cgactttttt ctccttgtca gaccaataat gaaggcgttc aaaagatcct tgtcgccagt
      181 agagtggtag cctttgtcga atatcctctt gcatgtctag cttatctaga tcagcaatag
      241 catgccattg tggtaggccc tctcgtgatt tagttagcag cttgccttca aaatcttcgc
      301 aaagaaagtc ataataaaca tagcgctcag gcttatcagg attggtaaag cctgagattc
      361 cctttaattg cagatttaag gcggttaagc cggtctcctc ctttagctca cgcactgccg
      421 cttcaaaaaa ggattctgag gtgttaacct tgccacccgg ttggatccag ccaggaaaat
      481 cgtcatgctg gcggttgaga agtaggatct tgtcgccctc cttgacacag atattaaccc
      541 aatttttgat gacttcaagc attagttacc tcgtttttag ttttatttta tcaaaaaaag
      601 atcagtatga atagctgaga gatttattga tatggtcata atggcttcag atagttttac
      661 tgctgcttta gccatctgca taaataatat aaaaatacca tttcacatca ttatttaata
      721 gatttattat catattaatg gtataattat gtgaaattag aactatgtgt agagagagta
      781 taatgaatag tacagatttg atgagactgg gagagcttta taaggagctt cgtattgctc
      841 gtggacttag gctaaaggac gttgctagag acaatttatc agtttcacag ctatctaagt
      901 ttgaaaatgg ccagagcatg ctggcagctg acaaactact attagctatt tcaggaatcc
      961 atatgacatt cgctgaattt ggtcatgctg taaatgggta taaagtcagc gatttttttc
     1021 agttaggcac caaggttgcc gagctacaaa cagcatcaga tatagatgga ttgaaggagc
     1081 ttctgagcca atataagggt gatgacattt tttctgttta taatagatta aatgaattaa
     1141 tcattaaaag tgctatctac tcacttgatc caaatgttaa aattgaagaa tcagacaagc
     1201 aattgttgac agaatacctt tatagtattg aagagtggac ggagtatgag ctatacattt
     1261 ttggcggttg tttggctatt ttatctgatg aggatatgat ttttttggga aaagcattta
     1321 tcgaacgaga taagattttc ctttctcttc cacaacatag aaaggcagct cacatcactc
     1381 tcttaaatat tatcatgaca aggcagcttt ttatgttgat ttttttatta aaaagctgga
     1441 ggagttgatt atctatcaag atatgttcac tatagtgagc ttaaattttt ttaagaaaat
     1501 atatacctac ttaaatgaag aaagtaagca taagagcgac attgaagatt atattaatct
     1561 tgttaaacag cttggcaacc ctcagtttgc ccaaattcta catcggacgc tatcagtgat
     1621 tctagatagt taatactaaa aaagtagccc aatcgtttgg tggctacagt ggccaaggcc
     1681 accaaataga caaaagggct aataagaaaa taaaagcttt tcgcataata tctcacctcc
     1741 ttgataagga tattatacaa aggggaagct tcaatctcaa acattcgcaa atatgaaaat
     1801 attaacaaaa gcatcatcat atttgcgaat atcgagaata tgataattgt cgtgatataa
     1861 ttactgtgtt aatgatttag ctaggcatta ataaatctaa atatagacta caggcaggtc
     1921 gctcgttata ctagtttgag ggccaatggt ctgggtagga ggaagcgtat ggcgacatta
     1981 gagcgacatc ataaaatgtt attattgtca atggcattag gggcagcgag ctggttagca
     2041 ctcggattga ttagcttgcc aaatcttgca ggtgctttag gaataagtac tgctaatgcc
     2101 aatactacag ttaatttgtt gagtgcttat agtacagttt ctagcgttgt tgcaatcgtt
     2161 ggtgctgtta cgggtgtagg gtctattgga gctggaattg cagctaccgt tttatacctt
     2221 atcaaacaaa aaggaaaggc tgctgctgct ctctggtagt taattgtctg atatgaagca
     2281 tgttttcaaa tatcataaag gcgacatttt agggtatctc aatattgttg ggtttaccct
     2341 tttgttttat ggctcagtga taggtatgat aatgttcagg gattatttga cctatgatgg
     2401 agctggttct ctaatatcga cctttattct ggtatcagga acctatcatt ctgtgaaatc
     2461 aacatttcca tatgaaggga agcgtcatcc aacttttata ttaacaccct attatctatt
     2521 taagcatcta ttgctttcag ttacaaaggt ttatgctttc cagatccgag tggttactat
     2581 aggaatcatc tgtttagcaa tagcctttcc ggagcagctt gtttggatag ccttgtctgt
     2641 gctagcagta tttatatatt ggctatcgct tccgctagta gccatttttc gagtagctgg
     2701 acgactcctg aatcttctca tgatttatgg tatgtatctt aatcaggagc tgctggtcat
     2761 tgcttgtctt tgtttaaatg tggttattct tgtgcttagt gttacgatta atgtacatta
     2821 tccctaccaa tggctggcgg tgagagctag gaaggaagaa aaaacaatta ccttgttaaa
     2881 gcttgttatc aatacgataa cagatcattt agctttaatg gttctgttta gtattttctg
     2941 tatagctgtg acctatttca cgcaaaggct gctgctaagt tttgattatt ctagctttag
     3001 cataccagtt tttttcttat ctgcttctac ctatatcgcg ttactagagg ttatggtcgg
     3061 taaaaatatt aaggagcttg agttagaccg gggcttggct gttttacagt ttctgaatag
     3121 ggatatcagt gtttacaaag cttatcgcaa cagccaattc ttgctttctg ctcacatctt
     3181 agctgttatt catacaggat gtgccatagg cttactacca tttttactaa atggtcaagc
     3241 tgctcttttt ctgtctaacc tagtgatgat ccccttcatc tactttatat cattttgcta
     3301 tttcgtgaaa tcactaaaaa tagttgctgg tgatttgtca gtgtttaggt gggttattct
     3361 ggttttgtat tttatactag tggtcattgc aatggtaggt agtcgtttat gataatgagg
     3421 aaatttttaa gatattatat cagttttatt attttctcaa tagcaattgg gattttaatc
     3481 ggtttgctga tcaccagtga tactgtcata ttatctaagc cagagcgggg ctgggatttt
     3541 actctggagg ttttgaagaa taatagcaat aattttttgt cctatatttt cctcttcttt
     3601 ttgtccccag ccttgcaatt gattgatttg gtatcagttg ttatacaaat tactctagga
     3661 atgaggaagt ctggatttct aataactgcc ttgggtttgt ttccgcatgg tttgctggag
     3721 atccctaatt ttctctttta tcaaggcttg agtcaatata tgctatggac tgttttgact
     3781 gaaaaaagca tgacgtcctt cttagaaaga gaaagaagat atgtaaggta ctatcttata
     3841 tcgtattatg ttttgttaat tgctggtatt atggaagggt tactcggatg aaaatagtaa
     3901 atgaaagcaa gtcattttca aacagaaaaa tcttaaatca catatccttt gactttagta
     3961 aagggctgta taaggttgaa gggaataatg gtagtggtaa aaccactttt ttgcgcttgt
     4021 tagcaggctt agaacggttt gatagcggcc atcgcttaca gcataaggga gatattctat
     4081 atcttgatac taatgctatc ggtgtagttc ccttaactat tgaagacaat ctgacattat
     4141 tatggaaaac ctttaatgcc tctcctgatg aggagacctt gtctgtgatt aatcagttct
     4201 ttggagaacg gttactagat cattatctga cggcttctgt aggaacaaag gctaaggtgg
     4261 gcttatcctt gctttttgta aaggattggg attatatttt catagacgaa gccctatcaa
     4321 cgcttgatgg gtttagtctt gatatggttg caggaagatt attagcatta aaagaaaagg
     4381 ctactgtttt ttacgtttct cataatctat cacaccagca gctattgtca gaatcacagg
     4441 tgatttatct taatggaaaa ggagaaatct attgaaaggt aatcctttta atcgtaatct
     4501 ttcttggtta atagcctatg tgctattact ttcttgttat gtattcatat tagtagatgg
     4561 tggtttttta aaaaacagcg ttcaagaatt ggaagtcctg ctcggccaaa catcactagc
     4621 tataaagctg tttttgatgg tgatatcaat agcttttagc atcatatctt tactggttga
     4681 gtatttttta agcaaatttt tagtgctgct ttttattgaa gctggcatcg tttctttaaa
     4741 tgatgttctt actgctaaat cagtgacttt agtgatccat ttatctgctt tgctattgaa
     4801 gctatctccc tctccacttt ttcagtttgt agtgaatgct ttagggattg tgatcatgta
     4861 tggattgagt atcaagagac aaggaaatag gacaactgct cttttgtttt gtttaccctt
     4921 tacactggat attctagcaa cattgttgct ttagtgattt tgagttggag gaaaagtaat
     4981 gaaaaaaatc ttatatttat cagtactttt aggaacgtca attctagcaa cattgattaa
     5041 aatttataac actttttttg caaagctaaa ggcttcatca ggtcattcaa ctgggaatat
     5101 agagattgat gcccttttat ctgagtctag actagtgttg gaaaggcagc atgccttcac
     5161 aacaaatgga atcaacaagc tattcgttat gatgatgagt ctaatgctgt tattagcctt
     5221 atactatctg ataaaaaagg atttgaaggc cgtctatagt tatttgcttt acctggtgtt
     5281 aaccttggtt catgcaattt atagcttctt ttcgttaagt cccttggcaa agctttattc
     5341 tgatgatatg ctgggggcta caatccagac gggagagaaa gctaaattga ttttttcagt
     5401 ggttcttttt cttctttatc tgcttattgt tgtggccaat aatagagtaa aatctagtgt
     5461 agaacccgct tcatctattg ggatagatgt gtaatacctt tcatattatg acctttaaag
     5521 ccttttagct tctctaattt tcagagtaac taggaggctg tttgtgacgc tctgagcgtt
     5581 ttttcgtttc tatcaaagtt tagctgcgtt aatgctatct atttccgtag ctgagataca
     5641 agatattata atatgtgttg tcataccata aaaacacctt acaggatatt ttatgatcaa
     5701 tcctccttga attaagcttt ctttaagcaa gggtgtgtat actagccgta atcctaaata
     5761 attggttacc taatgataac taattttttc ataacctcct tcctaaaaac gatgtcaggg
     5821 cagtcaggat tgattgctgt tatggcatcg tttttgttgt actttgatag gggatctagc
     5881 tgtatgttaa atagcctatc aggattgagt ggcgaagatg atcaggagtc tcttggctct
     5941 aggttatgct gctgtttcat gagaaacagc tcttgatgat caatttaggt agtattagtg
     6001 gtggtcatct tagcctttta ggctttgagc tgctttatgt ttgctcattt ttaatatgtt
     6061 agtgtttaca caaataattc tcattttttg atataataga aaaggtaagg aagggtagga
     6121 gataaggatg acaagatttt ttcaaaaaaa acaggccaaa agcttagcca ttggttttgt
     6181 gagcttgttt gctgtgctca ttgggtatgg agcttttcac tattctaagg ccagtcgtat
     6241 caatgcctat ctacaagcaa ggtcatcagg ctctgggcag gtgcttgaaa atatcaagga
     6301 atacctcgtg tgggcagata ccaatgagca gctgaccaat gatcaagcaa gatacaccag
     6361 ctttaagaga tacagtaagg cagagctagt aagcaagcgt cagcagctgc aaacagcaac
     6421 tgcagctgat gatatgtatg tcaaatcggt tggtcgcaaa tttttgattt tccctgatta
     6481 tcgcatagca gtgaagcctg tagccttgac aatcaagacc aatgtgccaa atgttgatat
     6541 cttgttgaac cataaaaaga ttgctgtatc acagtcagag gattttagca caactattga
     6601 aagactgccg gctgctgatt ataaggcgag tattaatggc tattataagg atcgtaagat
     6661 taaagtcagc aaggcctatg atggcaagaa ccatacacta gatttgaggg ttacctttaa
     6721 gacatttacg gtaaccagca atgtcagaga tggcgagctt tatattgatg gcgagcgcgt
     6781 ggaaactttg aaggctgggc agcttcagct ggaagaatac cctgtgacag aaatcgcaaa
     6841 ggcctatatt aaaaagacct ttcctgatgg cgagctaacc tccagcaagc attcccttgc
     6901 tcctgttgct gagggctccc agctagagat taacattgat cacctcttga ctgaggaaca
     6961 ggcgggacag gtgttggtgg cagcctttga tcaattgctc acctatctca atcaagggca
     7021 ggatccagca ggtctttcaa ctgtttttga gcaaggggct aataatgctt tttacaaagg
     7081 cttgaaggat tccatcaaag caaaatttca aactgatacc agaaaggctt ctcggttaag
     7141 cattccgtct attttgttaa gtaagctaac tcaaattggt aagcagtctt atctagtgga
     7201 ctttacagct gtttatgatt ttgtttacga taaggaaact gatcctgaaa aaggcacctc
     7261 agggaatgtt cgtcaagact tgactggtaa gctgaccctg aaaaaatctg gggatagcta
     7321 ccttgttagt cagtctggtc ctaaaaatat tacagttgcc agcgaaaaaa atcaggtcaa
     7381 gccgtctatt ttcccagagg ggctagtggg aacctggata ggacatcgtt cggacatgac
     7441 ctttacgatg atattggcta aggacggcag catcacaaca accattggaa acaaaaatgg
     7501 gaatggctca cagaccacta agtctgctaa aattaccaag gtagaggaaa aaggagatgg
     7561 cttgttcctc tacactgtag ctccagatgc tgatatagca gctcttgttc caggaggtgg
     7621 attgggtggt gtcaatgtca aatacgcttt tggtgtcaaa tggagtggag atgtcgctac
     7681 gatagtggtt tggcagacag caaataatgc ggcatttgat tacagtaagc caatgcttgg
     7741 ccctgacatg aaaaagcaat aagtacttta ccctacaagt tggtctagca tttattgcta
     7801 ggaggaatca gcataaagaa aaagcctctc ttttaatctt ttgtggttaa gaagagaggc
     7861 tttttagtat agggctgact gtatgaggag caaccgatgt aatcaattta gctgctgtag
     7921 tccttcttta aagcttttag acggggcagt gaccctaatc atctcttgag ccaaggggtg
     7981 tctaagggtt agctgatgag cgtgcagcat gagacgctcc gctttttgcc tgctatagag
     8041 gggatcacca attagagggt gtttatgatg agcgagatgt actctgattt gatgtgttcg
     8101 tcctgtctct aggcgacagt tgactaggca ggtctgatca aaggcttgta ataaggctag
     8161 atgggtgatt gcctcttgcc catgcttact atcaaccaca cgcttgcgcc tatcgtggcg
     8221 gtgacgtccg attggatcgc gataggttac tgtttgctgc tctagctgac cttcgattag
     8281 ggcccaataa tctcgcttaa tgtctcgatg ctccaatagg cgatttaaga tcggaaggat
     8341 aaagggattt ttagcaaaga gaatcgctcc actagtctcc atgtctaagc gatgaaccac
     8401 atagcaggtc ttgccagtat aggcagagac atggttgagc aaggcgagct cagtgggctc
     8461 attgccatgt gttttcatgc cctcgggctt gttgacaatg atgaggtgtt cgtcctgata
     8521 caggcaatcc actaggccag gcttacccat taagatgcct ttatcagggt agtcttcttg
     8581 gtcaaattgt agcttgatgt gatcaccctg cttgacaggg ctctgccagt taatcagctc
     8641 atcattgacc caaacatgct ttttgatgcg caagaaatgt ctgattttac ggggaatcaa
     8701 tagcctatct tctaataact ccttgacagt tgtcgcttga taggggttaa tgaaggagat
     8761 ctgaaagccc atctcaggct tatttgctgt tgtcattgag ccagtcatgg tatttttcaa
     8821 tcaaattgat ggccatttgg gttgcaagag ttacagagaa agcctcggtt ccctcgcgct
     8881 cgtcactggc aacctctaag cgtgtctcat catagacagc cttgaggctc tctgctgaca
     8941 gggtttcttt aaaagcttga aatttgttca tgatcatgtc ctacctttct aaatgtttgt
     9001 gacaatgcta ttatagcata tttttcatca aagctaatca tttgctcgat gatttgtgct
     9061 gcgctaacag cgtgattctt ttgagaaaaa ataagattag ctattgtgaa attgtctgtc
     9121 ttttattata ctaagaatag tctgataaat atattattta aggacacgat aacattggga
     9181 ttatgaatca tttaggagaa tactattgaa caagccattg ataaaatcct gtttgcttgc
     9241 tctattgacc ttggccggct tgaccagtat ggcagcacag gctgatgtca acacttacaa
     9301 ccaaggtagg acatataacg atacacccta ttattctgct tatcatcact actatgacca
     9361 cacgagggat actgctgaca atggtattga taattggggt cgtctgacac gctatcacta
     9421 ttacagagag acctattatc agcttgaggc cgagcgtcag cagcttgtta ggacttactt
     9481 ggagttgaag gcttcatatg atgatcaggt ggctcttagc agtcaacgac tacagcagta
     9541 ccagtctggc tggtctgatc tccaatcacg ctttgagcag ctcaggaaaa ccaatcctgt
     9601 tgtaggcggt gattatcgga ttgttgagct agagggcaat tttcaaagct atcagacctt
     9661 gctgcagcag ctttctatgg ctgattttgt cagccagtac aaagataggc tggatacctt
     9721 gactagactt gatacagagc gagctaggct cattgacacc tggtgggaaa gtgatagcaa
     9781 ttactcagat ctcaatacca atctaacact agtcaatggc tatatcaagg agctgaatca
     9841 ggctttacag gagcttctta aggaccatca aggtaaaatg acatcagatc tgcagacctt
     9901 gggtgaccga caggccgagc ttgctagacg gctgacagat atagaaagca ggcctaagag
     9961 acaggctacc agtcaacctc gtggttcaca gacacattgg cgatcagccc ctagagctga
    10021 tgttgccttg tggaatgaat tgcgaaacga aggagattat gcttctgcta cgacagacaa
    10081 tgctttgcca ttgcagcctt atcgagcgga cttaacagct gttcatgatc tagaagcctt
    10141 gcaagcacaa tctgatagag cacaccgctt gcgggcaaag gaaattgtct ttacactgca
    10201 gcgttctaac attagtcgtc agggcgatat agatttgtca ggagccatta cagcatttat
    10261 caaagaaaag cttctcgtca ctccaaatgc gcgtggggta tcatctggct ttaggtggca
    10321 aatgcaaacc tatgacaatg agcgcttaac catcactcta atgcctcaat attatatgac
    10381 tgatgatcag tacaaggagt attacgacca tctcaaggct tggacagctc agcatatcca
    10441 gtctaccgat acagaggttg agaaaattga taagattcaa gactatatca tgacaaacta
    10501 ccactatgcg accggcaagg ttggaggagt gacccgtact ggcatttctg tgcagacgcc
    10561 atatgccttt atcaaggaca aggaggctgt ttgtcaggcc tatgcacaga tgtttaagga
    10621 catgggacga ctagctggac ttgatgttca ttatattcaa ggctatggag acccagttgg
    10681 cggcttatca agtctacatg cttggaatat cgtcaaggtt gatggtcaat attatcatat
    10741 tgacctgact tggaatgata ctattgacag caccaatcac aatcatacct acaccctgcg
    10801 aggcaatgat tttatgagca aaacacattt gtggaatgct gcctatgcga tctcagatag
    10861 tgactatgct gcttatccta ggaggagctt cctgagatat gggacctatg cgactaacta
    10921 ttcaagaaat acattttatc caggatacag ttatgcttaa taatagctaa taccatcaaa
    10981 agccctagaa agcttgcttg attctttcag ggctttttga tatgtcatgg tttttggtat
    11041 aggattttga aagaaattgt tataatagga taaaatgctt atgtaacagg agaaaataaa
    11101 atgaagagta ttagacgcta tgatgtcaat gaagagtggg cacatactgg cttagtagag
    11161 gcaggcgatt tttatttttt aaattattgt gtaggaaatg tcggtcaaga tattgaggct
    11221 caaattaacg gtgcctttga tgaaatggag cgtcgtttgg ggctggtagg gctgacgcta
    11281 gaggtcgttg ttcaaatgga ttgcttgttt agagacattt ggaatgtgcc agttatggaa
    11341 aaaatcatca aggagcgatt taatggcaaa tacccggctc gtaaatttct tcaaacagcc
    11401 tttgctcatc agggtggtcc ggacggcttg ctatttcagg tagatggggt tgcttattca
    11461 aagcatatct ccgtatccta aacaatatga cttggaggct tagtagtatc ataaggctat
    11521 gacattttta gaattattac aaaagaaatt ttttccaaaa aaataccaag aaaaacaggc
    11581 cttaaaggaa agggcagccc agcatatggc tgacaaagag gctactactc aggctactgc
    11641 cactgctttg gccgatcagg aggcacaggc agggcagact gagaggcaat cagtccttca
    11701 acgcagcaag tcctatgggg tcaaaaggaa aaatcggccg atctggcttc aaaggctgga
    11761 ggcgattttg ccatcgcagc aaggtcctat tcgccgcttt cttcgtcgtt accatgttgg
    11821 taaaatcctg ctgattttga tgggtacctt tgtcttgctg ctggggtctt acctttttta
    11881 cctttcaaag acagctaagg tttctgactt gcaggacgct cttaaggcga cgacagtcat
    11941 ctatgaccgc aagggagaat atgcaggcag tctttctggt caaaagggga cctatgtgga
    12001 gcttgacgct atttcagatg atttggaaaa ggcggttatt gccacagagg accgtacctt
    12061 ttataccaac aatggtatta atttcaagcg ctttttattg gctattgtga ccgcaggacg
    12121 ctttggtgga ggctcgacca ttactcagca gttggctaaa aatgcttatt tgtcccagga
    12181 gcagagcatt aaaagaaagg cgcgtgagtt tttcttagca cttgaattga ccaagaaata
    12241 cagtaaaaat gacattttga ccatgtatct caataattcc tattttggaa atggtatttg
    12301 gggtgttgag gacgccagtc aaaaatattt tggtacctca gcagctaatc taaccttgga
    12361 cgaggcagca acccttgccg gtatgctcaa gggacctgaa atttacaatc cctattactc
    12421 aatcgaaaag gcaaccaacc gtagagatac tgttttgtca gccatggttg acgctggaaa
    12481 aatcagcaag cagcaggcac aagaggccca agctattggt atggggaacc gtttagcaga
    12541 cacctatgtc ggcaagacag atgattatca gtacccatct tattttgatg ctgttatcaa
    12601 tgaggctatc tcgcgctatg gcatctcaga aaaggatatt gtcaatgatg gctacaagat
    12661 ttacacagag ttggaccaaa attaccaagc aggcatgcag accaccttta atgaggatag
    12721 cctatttcct gtgtctgagt ttgacggcag ctcagctgag gcggctagtg tggctctaga
    12781 tcctaaaacc ggagctgtca gggggcttgt tggtcgtgtc aatagcacag aaaaccagcc
    12841 ctttagaagc tttaactatg ctactcaagc caagcgtagc cctgcttcaa cgatcaagcc
    12901 cctagttgtt tatactcctg ctgttgcagc aggctggtca ctggagcacg aactgccaaa
    12961 cagcgttcag gattttggcg gttatcagcc gcataattat ggcaattacg aatcagaaac
    13021 aattcctatg tatcaggctt tggctaattc ctacaatatt cctgctgttt caattctgga
    13081 tcagttgggg gtggataagg cctttagcta tggtgaaaaa tttggtttga agatgagtga
    13141 aaccaaaaag gagcttggag tggcgcttgg tagtggtgtc accaccaatc cgcttgagat
    13201 ggcacaggcc tatgcagtct ttgccaatgg tggtgtcaag catattgccc acctgattac
    13261 cagaattgaa aatgctaagg gcaaggttat caagaccttt acagacaaaa ccaagcgggt
    13321 tatcagtcaa tcagtggctg ataagatgac tagcatgatg cttggaacct tttctaatgg
    13381 tacagctgtt aatgccaatg tctatggcta tactctggct ggtaaaacag ggaccacaga
    13441 aactgacttt aacccggacc tttccggtga tcagtgggtc attggctaca cgccagacgt
    13501 tgttatcagt caatgggttg gcttcaatca aaccgatgag catcattatt tatcagattc
    13561 aagtgcgggc actgcctcag caatttttag cacccaagcc tcttatatat tgccatatac
    13621 caaaggaagc caattcaagg tcgataacgc ttacgctcaa aacggtattt cagcggttta
    13681 tgggattaat gagaccaata cgcaagcagg tattgattct caatccatca ttgatagtct
    13741 tagaaagtca gccgaggaag cttcaaagtc tatttcagag gcagttgatc aatctggtct
    13801 cagagaaaag gcgcaaagta tctggaagag tattgttgac tactttagat agcttgcgaa
    13861 aatatctaaa tcgtgttaga ataatcacta cggaggcgtt atggcacaga aaaaagcaag
    13921 cctagcgtgt gtagaatgtg gcagccgcaa ttattctatc gggattagta gcacgcctag
    13981 accaacacga ctagaagtca ataagttttg caaatattgt aaagcataca ccttacacaa
    14041 agaaacacgt tagaggagag cctgatggga ttcattagtg ggatttttaa gcttttaagg
    14101 gatacaactt ggccggatcg taagcagcgc tggaaggact ttatttctgt ccttgagtat
    14161 acagcattct ttacggtaat catctttatc tttgaccagt tgctatcaaa aggcatttta
    14221 tcattgatta atttattcta agtcattgca atgatgagac ctgttatgat taaaattgct
    14281 tggaaaagcc taggctgaaa caatcgtttc ggcctttttg agtgcgatgg gcaggttgta
    14341 ctctgataga tgcaagacca atagaccacc tactatgcgg gtgcgtaaag gggttgatag
    14401 ctaccgatag ttaagggcta tagcaagtag aaaggcttgc agctcagctg atccgctgtt
    14461 atgactaaag gcattgacca gaaaggttcg ttggcagcca acaaagtgct cttaccctgc
    14521 tatgaggggc tattaatgcg ttgacagcca atccttcttc tattataatg aaagtgtgat
    14581 aacagcaatg caaaggccag cagaggcttt tttataatga aaggaagtaa catgttagat
    14641 tcttttgata agggctggtt tgtccttcaa acttactcag gctatgaaaa taaagtaaaa
    14701 gaaaaccttt tgcagcgtgc tcaaacctat aacatgctag acaatattct ccgcgttgag
    14761 attcctaccc aaacggtaaa tgttgaaaaa aatggtcagg tcaaagaggt tgaggaaaac
    14821 cgcttcccag gatatgtttt ggttgagatg gttatgactg atgacgcttg gtttgttgtt
    14881 cgtaacacac caaatgtgac aggctttgtc ggatcgcatg ggaaccgctc aaaaccaacc
    14941 cctctacttg aagaggagat tcgtgctatc ctgttgtcaa tgggacaaac tgttgatgtc
    15001 tttgatacca acattaaaga gggcgatatg gttcaaatca ttgatggcgc ctttatcggg
    15061 caagagggtc gtgtcgtaga aattgaaaac aacaaggtca agctcatgct taatatgttt
    15121 ggctcagaaa ccttagcaga ggtcgagctt taccaaatcg cagagctatc gtcctgatag
    15181 gctcctaaag ctattattca taccataaaa aataaaaggc tggcatcggc tctctaaaat
    15241 accgatgtta ggcctttttt gttggtcttc tacaaccaag actcaaatta accaaaccct
    15301 aaaaagagtc atttttcctt cgctttttaa gtctctaact gatcgcccta gcttattttt
    15361 aatctagtaa tcgcaacagg tcaagagtta aatgatatcg cgccgttatt gattggtata
    15421 gacaaaaata cgctcaaaaa aagaaaaaag gataggtaat atagtcctgg tttgcttgat
    15481 agatggtggt tggcaaccaa ccattcgagt actttcctta actataaact cctaatcaat
    15541 tctagcgttt aaaaaataag attattcttg gagggaagca aagagcttct ctcctttttg
    15601 agttgtagca ttcttgatcc tgatcttata agcagagtcc tgtttgccgg gctgttgaga
    15661 tgaataaggg catttctata gtgattatat agtgttgcag atgtgtgtat ggtttaaggt
    15721 ctaaataccc ttcaagctta gttcttgggt agtcagttcg gattggctgg ctgattttta
    15781 agcctttaat ggcttagtgg taagacaaac cagattacat ttgctaaaaa gtccctaagg
    15841 ctacaatcat tttttgtgac taatataaaa actagacctt ttgggatttg taataattta
    15901 gattattgtt tttaaaatta gcaaatatta aacgcttttt tattgaagat acagatgata
    15961 gtaatggcag agctaaaaaa taagagaaaa taaaaaaagt ctacaattta taatgtaata
    16021 aaaaaatgag ttgactgttg tgttttaaag gcttttgtct atttgtaatc ggttaatttg
    16081 caaacaattc taaggtattt ctggctaata gtatgctata atgtaatact gttctacaac
    16141 cgacattaag agttaatgaa atagtgttgt gttgtggtaa gtttttaatc aggaagagta
    16201 tatttaggag ctagatacca tgtctataga gaatctcttt accaagcagc agtggcgaga
    16261 gcttgagttg attactttat taagtgaaac gaaaaatcca ttatattata aagatgcttg
    16321 tcagatgctg gattgttcgg ttttaacgct gcaatcgtgt atcacgaatt ctgtttttat
    16381 ggaagattta ggcaagctgt tctacaagga ttctcaattt catattcatt acaatcatca
    16441 aagtggctta aaggaggttt atcggagagc cttgctagag tctccttctc ttcagttgat
    16501 gtcggccttg ttttttgatg attttgcgtc attagatgat cttgcagagg cactttttat
    16561 tagcttgtca accttaaagc gcttgattcg taaaaccaat ctctatttaa aagagcattt
    16621 tgatattatc atttcggcta agcccattcg tgtagttgga gatgaataca atattagact
    16681 gttttacatc aagtattttt cagaagcata taccttttct gaatggcctt ttgcttctct
    16741 acttaatgaa aaccaccatg agcaatttgt tcaattaatg gcatctttga tagaggttaa
    16801 gattgatttt gcgatttttc gtcaactcaa gctattaagt gcggttaatc tcattcgcta
    16861 cctcaaaggc tttaaaattg ggaagcataa agcactgagt agtctttcat tggagttgtt
    16921 acaggattct caggagatga aaaagctgtc gcatttgttt gtgcttaaat tttcagtacc
    16981 gcttgatgag cttgtcttgt cagaaatgtt ttccaattat ttagatgatg atttggtatt
    17041 agaaaaatcc ttgcaggtag ataaggttaa ggaggaggtt ccgggtcctc agtccttgct
    17101 gagctggata gatttgctta gtgaaatgga gggagctaca ggtattgtat tgccaaataa
    17161 atatgaggtt gccagatatc ttcatgccac tgttatttta ggagtggagg atattagtga
    17221 aagctttctg atttacgatt ataaaaagga ttacttggcc ttctttaagg agcattatac
    17281 ctatgtttat tttaggttta ccgattatgt gaagaggcta tttaaggacg gggatatgga
    17341 gcttgctact aatttgctca acaatttggt ttattccttg ctgatagcct gggagaattt
    17401 ctttttaacc atgtgtgaat tgatgaaaaa accaaagctc ttgattatag aaagaagtca
    17461 tggcagtacg ggaagctttt tgaaaaaata cattggtgaa ttttttgaga ttaccatttt
    17521 tgataaatta accatagaag ccttgtgtct acagcatgac tatgacgtca ttattactga
    17581 tacggtcatt aggggctgtg agcatgctga tatctttttc tttagtcgat ttgtgccaac
    17641 cgttatagtc gccaagctta accattatct aagaaaacga atgggtagta tctttgaaac
    17701 gaaaacaact aacaagcttg ggaacatcgg ctattgatag atatcggtat atttcattaa
    17761 aatagccaca acttgtcatg gtgtaaaatt agtgagcttt gttaatccaa taaaattagg
    17821 tagaatatag ctataggcca acgtgtaatt cccttaggga gtaggtgctt tggtctggga
    17881 aagagaaaaa taaaaaggag aaacaaacaa catgaagagt tgtaaatcaa ccctagttta
    17941 gataaaaaga ttaattcttc tattggtatc aaaggaagta attttatttc ctcaaaactt
    18001 ttagcgaatt taaagactcg catcgactct gaagctactt tgaaagcaga aacaactcaa
    18061 ttgaaagccg atatagaaag agaaaaactt acttctaaag aattaagcac taaactggaa
    18121 gaggtaacat cagatcgtga taatgctctc agtgaatctg ccgatcttgc caacaaactc
    18181 tcagtagctc aagcagaagc agatcgttta agtcaggctg ttgatagtct gggtcgattg
    18241 actaactctg ctaagcgtga gctcacagag aagcttgctg agattgatca attaacacag
    18301 gacaaggtta aagcagagac tgaccttgaa actgctaatg ctaacatcac aacacttcaa
    18361 gaggagctgg caggtgctaa ggctaatgtt gataagcttg caaaggaaaa agctgcggca
    18421 gatcaggcac ttgctgaagc taatgcaaga gtatcaaatc ttgggcaaga ggtagcagca
    18481 gctaataata gagtggctga ccttgaagcg caattagctg aaaaaacagc cgagcttgat
    18541 gtggttaagg cagacaaggc agagcttgag gctaaggtta aggagcttca aagcctgctt
    18601 gagcaaaagg atcgtagcaa tgctgatctt caagctaaca ttgagcgctt gaagcaggag
    18661 cttgctgaca agtttaagga tcaggcacag cctcgttcta agactcctca ggcatcgaac
    18721 tcggttgcaa agcaaaaagc aagtaagcca gccgcaaaac cagcaggcca gctaccatca
    18781 acaggtgaag ctactgcaaa tccatttttc actgctgctg cagttgcgat tatgacaagt
    18841 gcaggcctag taacagtcat gccaaaacgc caaaaaaatt aagctattct caattctctc
    18901 ccctttaact attgttttat agcattttac taatggacat tggcattcct ataaactcta
    18961 ttgagcttct tatctgatag caaggataag gggcttttta gtagcttagc aagcactcct
    19021 tggtcaagct caatacctct ttgagagctt aaaactagag ctagaccaga tctaaaacca
    19081 agtgagatga tagcggatat ttggctgttt tatgagttgg ctcgtaaggc ttgagcttat
    19141 gcgtcgcaga gacgcgctat ctagtctaaa gggctttagc aatgtcgtga caaacgcatg
    19201 aagacagtta cactttctca tagcgagttt ttatcatcag tatagttttt ttggcaatat
    19261 gttatgaaat agtcaaatag caatcgagaa actggtgata ttgcaatgca aaaccgctga
    19321 acatagatta aaaaaatgca tgcagctaga aaatggttac atgcattttt gtgatgccga
    19381 cgtcgtggca gcaatattgc ttgcccattc ctaaaagtct gatatcgtgc tataataaga
    19441 agactagact ttttacatgg gagaattcac atgacatttt acaatcacaa agccattgag
    19501 cctaagtggc aggccttttg ggctgataat cataccttta aaacggggac agatgcctca
    19561 aagcctaaat tttatgcttt agatatgttt ccttatcctt ccggtgcagg tcttcatgtt
    19621 gggcatcctg agggttacac tgcaactgat attttaagcc gcttcaagcg tgcacagggt
    19681 tataatgtcc tccacccaat gggctgggat gcctttggtc tgcctgctga gcaatacgcg
    19741 atggatactg gtaatgaccc tgctgagttt acagcagaaa acattgccaa ctttaaacgt
    19801 cagatcaatg ctcttggctt ctcgtatgac tgggatcgtg agatcaatac aactgatcct
    19861 agttactaca aatggacaca gtggattttc acaaaattgt atgaaaaagg cctagcctat
    19921 gaagctgagg tgcctgttaa ctgggttgaa gagctgggaa cagctattgc gaatgaggag
    19981 gttctccctg atggcacatc agagcgtgga ggctatccag ttgtccgtaa gcccatgcgc
    20041 caatggatgc tcaaaatcac agcctacgca gagcgcttgc tagcagatct ggaggaagtg
    20101 gattggccag agtcgatcaa ggatatgcag cgcaactgga ttggtaaatc aacaggggct
    20161 aatgtaacct tcaaggtcaa agataccgat aaagacttca ccgtctttac cacacgacct
    20221 gataccctgt ttggtgcaac ctatgctgtt ttggcaccag aacacgcctt agtagatagc
    20281 attactacag cagagcaagc gcaggctgtt gctgagtaca aacgccaagc gagcctcaaa
    20341 tctgaccttg ctcgtaccga tcttgccaag gaaaaaacag gtgtctggac aggagcctat
    20401 gcgatcaacc cggtcaatgg caaagaaatg cctatctgga ttgcggatta tgtgcttgca
    20461 agctacggta caggtgctat catggcagtg ccagcgcatg atgagcgtga ctgggcattt
    20521 gcaaagcaat tcaatcttga gattattcca gtgcttgaag ggggcaatgt tgatgaggct
    20581 gcctacacag aggacggtat tcacattaat tctgacttcc tagatggtct tgataaggct
    20641 tgtgccattg ctaaaatggt ggcgtggctg gaggagactg gtgtcggtca tgaaaaggtc
    20701 tcttatcgcc tacgtgactg gctgttcagt cgtcagcgct actggggtga gccaatccca
    20761 atcattcatt gggaggacgg tacctcgaca gcggttcctg agcaggacct accacttgtt
    20821 ttgccagtga ccaaggatat tcgcccatct ggtacaggag aatcaccact agctaacttg
    20881 actgactggc ttgaggtgac ccgcgaggat ggggtcaaag ggcgtcgtga gaccaacacc
    20941 atgccacagt gggctggctc aagctggtat taccttcgct atattgaccc acacaatgat
    21001 gagcaattag ctgataagga cctgttaaag caatggctgc cagtagatat ttacattggt
    21061 ggtgctgagc acgcagtgct tcatctgctt tatgcacgct tctggcacaa ggtactctat
    21121 gatctgggtg tagtgccaac caaggagccc ttccaaaagc tctttaatca aggcatgatt
    21181 ttgggaacca gctatcgcga ccatcgtggg gccttggtcg caacggataa ggttgacaag
    21241 cgtgatggta gcttcttcca catggaaaca ggcgaggagc ttgagcaggc ccctgctaag
    21301 atgtctaaat cactgaaaaa cgttgtcaac ccagacgatg tggtggagca gtacggagca
    21361 gataccctgc gtgtgtatga aatgtttatg gggccacttg atgcgtccat tgcttggtct
    21421 gaagaaggcc ttgagggagc acgcaagttc ctagatcgtg tttaccgttt gatcacgaca
    21481 aaggaaattg ttgcagaaaa tagcggagct ttagataagg cttaccatga gactgttaag
    21541 gcagtcacag aacaaatcga aggcatgaaa ttcaatactg ctattgccca gctcatgatt
    21601 tttgtcaatg cagccaataa agaggacgag ctttatgtgg catacgccaa aggcttcgtt
    21661 caattgctag ccccatttgc cccacaccta ggtgaagaat tatggcagat cctgacagct
    21721 tcaggtcaat ccatctcgta tgttgcatgg ccaacccatg acgatagtaa gctcgttgaa
    21781 aatgatgttg aaatcgttgt tcaaattaaa ggaaaggtca aggctaagct tgtcgtggca
    21841 aaagacctct caagagaaga gctagaaaaa gtagccctag cacatgataa aatacaggct
    21901 gaaattgcag gcaaggaagt ggcaaaggtc atcgttgttc ctaataagct cgttaatatt
    21961 gtggtgaaat aaagacccta gcaaaaaatg ccttccttat aattttgagc ccaatactat
    22021 aaaaagctga taaccactcg tttacatgag tggttattct tgttttgtaa cacgctatta
    22081 aaactgatat tgaagaagct tgaagataat agtaaaataa aaccctaaac ttatttaata
    22141 aatggaggat ttttcaacgt gaaaaaatta gttttagcca gtgcagcagc acttgtatta
    22201 gcaggagcaa ctgtaagtac aggaacagta agtgcgaata gttcaagata taattatacc
    22261 ggttggaatc aaggtgggta ctcatggaaa tatttgcgcc taagaaataa aaatccttat
    22321 tcacgtcgta cccttacaga agactattct gatcaaagaa agaatgaagc aaaagatagt
    22381 attaaagaat tgagtaagct tagtgataaa gagaaaaaga attttgctga tagaattgat
    22441 gctttgactg acacctatgc aatcagctct attctatcag aagctaaaaa taagaataat
    22501 gactatttag aatttgataa agaatatgag gctttattca attcaaataa gtataagtta
    22561 gaaatagaga aaataaagga tcgtgtgtac tttgatgaag gttactcagc tagacaaggg
    22621 attaatgact tgaaaagtct ggagaattaa acagtagaca gatttattat ttatcaa
//
LOCUS       DARYJX010000038        20895 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYJX010000038 DARYJX010000000
VERSION     DARYJX010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20895
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            126..1541
                     /locus_tag="TU257_001540"
     CDS             126..1541
                     /locus_tag="TU257_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0834542.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1743..5494
                     /locus_tag="TU257_001541"
                     /pseudo
     CDS             1743..5494
                     /locus_tag="TU257_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5723..6628
                     /locus_tag="TU257_001542"
     CDS             5723..6628
                     /locus_tag="TU257_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL0834543.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6612..7496
                     /gene="isdE"
                     /locus_tag="TU257_001543"
     CDS             6612..7496
                     /gene="isdE"
                     /locus_tag="TU257_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL0834544.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7498..8520
                     /locus_tag="TU257_001544"
     CDS             7498..8520
                     /locus_tag="TU257_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0834545.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8517..9299
                     /locus_tag="TU257_001545"
     CDS             8517..9299
                     /locus_tag="TU257_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834546.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9345..11108
                     /locus_tag="TU257_001546"
     CDS             9345..11108
                     /locus_tag="TU257_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL0834547.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11101..12783
                     /locus_tag="TU257_001547"
     CDS             11101..12783
                     /locus_tag="TU257_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834548.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12764..13357
                     /locus_tag="TU257_001548"
     CDS             12764..13357
                     /locus_tag="TU257_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0834549.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13354..14034
                     /locus_tag="TU257_001549"
     CDS             13354..14034
                     /locus_tag="TU257_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0834550.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13971..15425
                     /locus_tag="TU257_001550"
     CDS             13971..15425
                     /locus_tag="TU257_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834551.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15789..17804
                     /gene="recG"
                     /locus_tag="TU257_001551"
     CDS             15789..17804
                     /gene="recG"
                     /locus_tag="TU257_001551"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL0834552.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17924..18889)
                     /locus_tag="TU257_001552"
     CDS             complement(17924..18889)
                     /locus_tag="TU257_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL0834553.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18961..20349
                     /locus_tag="TU257_001553"
     CDS             18961..20349
                     /locus_tag="TU257_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0834554.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20635..>20895)
                     /locus_tag="TU257_001554"
     CDS             complement(20635..>20895)
                     /locus_tag="TU257_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0834555.1"
                     /translation="AKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEEVD
                     LIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
BASE COUNT         5598 a         4151 c         5093 g         6053 t
ORIGIN      
        1 aataagaaaa ggcccttacc tttatccgag tattaaggca ttaatacaaa aaatcttgca
       61 ttttattttg cttcaatgtt ataatgtagg ttagaataga gcagaaagaa gtgattgaat
      121 actaaatgag aaaaaataaa ttattaagaa tgataatgct gatgactctt ctggtacctc
      181 atttagagac cgcaagagta ttggcagagg atacaggagc tgaagccagc caggttccag
      241 ctactgctaa tgaggctgca atcgcccaga ctggtgagtc cacttcgaca gcagctgcta
      301 cctcagctac tgacaactcc tcatcaacca ctgagactac tcccaacagt ggagaacctg
      361 gagcaacggg gtcatcaagc aatacagcta gctctggatc agcttctggt tctactggac
      421 agtcgacacc tactagtcca gcagctagcc ctcagccagc ccctgaagtt gctacacagg
      481 catctcagcc ggcactgaat attgttcctg ctgctcctac agttgatttg tccttgactc
      541 tggccctgcc ttctgtaaat acctatgctg cttatgtgac gcattggagt ggtcagagtg
      601 cttataccca taacctcttg tctaggcgct atgggatcaa ggcagagcag cttgatagct
      661 ttttaaagtc taccaagatc aagtatgatg agaagcgaat taacggtgct gccttgctgc
      721 aatgggaaaa aaagagtggg ctagatgtgc gggcgattgt agccattgca atgacagaaa
      781 gtgagctagg aaccaaggga aatgcaacct tactaggctc taacatgttt ggctatgcgc
      841 tttttgacct tgattcgaaa aagccaaatc agtttaatga tgagcttgct attgttaagc
      901 tgacacagga gacgattatc aaaaatagca accttaattt tgagcagcag gatcaaaagg
      961 ctgataaatt tgccaaaaag cagttgaact ttgctagtga tggtggtctt tacttcacag
     1021 ataccaatgg cattggcaag cgtcgcgctg agatcatgga aaaattagat gcttggattg
     1081 atcagcatgg aggcacgcca gagattccgg ctgagctgaa aattcaatcc tcttcaagct
     1141 ttgctgttgt tcctacaggc tacaagctgt ctaagagcta tgatatttta agctatcagg
     1201 cgtcaagcta tgcttgggga caatgtacct ggtatgttta taatcgcgct aaggagctag
     1261 gctatcagtt tgattccttt atgggaaatg gtggtgactg gagatttaag tctggctaca
     1321 gtatttctaa ggagccaaag gtaggctatg cggtttcctt tgctccaggt caagcgggtg
     1381 ctgacggtct ttatgggcac gtctctattg ttgaggatgt cagaaaggac ggctccatcc
     1441 tgatttcaga gtcaaattgt cttggcttag gtcagatttc ataccgcacc tttactgctg
     1501 agcaggccaa ccaattgact tatgttgttg gaaaatcata agtaatcttc ttgctttaaa
     1561 ggcgagaagt acagaatttt tgtaagaaaa aatccagctc tgttgcaggg ctgttttttt
     1621 ctttgcttta ttgtgaaaaa aatctcaaat tcaatcttga caaaggcttg acaacataat
     1681 aaattaagtg agattaataa aataattaaa tggctaataa catttttaga aggttcgaaa
     1741 taatgaaaag tatcaataag tgcgccattc ttgctttatc aacgctggct cttgcccagt
     1801 ctgcccagac ggttcgctca gaggctactc aagtctcttc aagtcttgtg acgactgtca
     1861 agcttaagga taatatttta ttgttcgagg agatcggtcc ctatgcggac aagtcagagg
     1921 ggaagctcta ttataaaaat atcgagaaaa ttctcattga tggtaaagag tatgacaaaa
     1981 agctggaggg tgactatagc tatgacatca attaccaagg aatcaaggta aacgctaaga
     2041 acatcacaga aggacagcat cagctgcgca tcgtcaataa gactaacgga ggcattcttg
     2101 tggtctttga caagaaagga aatgatgtta cctttgtttc tgccaagcct tcagatgata
     2161 ctactgcttc accgcagcaa gctgctgcta agacagaaaa gcctgctaag gtaactagcc
     2221 atgatggctt agcgacccta tcatttatca ccaaactaga gacaacagaa ggagagcttc
     2281 tttttccgga aattgatcgc tattccagca ccaagcaaat taaggaatta gctcatcaaa
     2341 tcacaaagat caaggtcaat gaccaggact ataaggattt ggtctatgat tcagtaaagg
     2401 acaagcctgg ctatgtgtct gacctgaagg ggcttcatct tgggacgaca gctttcaagg
     2461 agggagaaaa caaggttgtc atttcctcac aaagctttga agatgtcatc attacagtga
     2521 aaaagtcagg ggagcaatac acctttgttt ctgctaagca aaagcagaga caaggatccc
     2581 agcaggaagc accgcaggga cttgatttta ctaagctgga aagcgcgatc aaggaagctg
     2641 agcgtatcat tgctagcgag gccaataaag aacaggtcaa ggacttgtct agcaagcttc
     2701 aggtgatcaa ggagtcctat cgtcagattg acaatgaaaa attgctcaag gagacctatg
     2761 agcttttgat ggatagtatc aagtcctatc agggaactga tctggctgtt acggatctaa
     2821 aggcaggaac ctatacctta acctttaagg ccaataagga aaatacagag gaagcctcaa
     2881 tgctgcaggg agcatttgat aagaaggcca agctggtcgt caaagaagat ggcaagatgg
     2941 agatttcatt gctcaataca gctctagggc aatttttgat tgacttttcc attgagagta
     3001 aagggcagta tccaacctct gtccgcactc aggttggtga acgcgatatt aacaataact
     3061 acattagagt gaatttaccc taccgattga ggagctggac aagcttcaca agggtgctgt
     3121 gctagtatca gctatgggtg gtcaggaaag cgacctacat cactatgaca aatacaccaa
     3181 gttggacatg acctttagcg ctacagcaag taagggctgg acaggctatc aggctgagat
     3241 tgacgacaag gaaaaagggg tcggctctga gcgtcttgaa aaggttttgg ttaagcttgg
     3301 taaggacctt aacggtgatg gcaaaatgtc acctgaggaa attgcgaaga ttgaaggtga
     3361 gctgcgccta gaccactatg atttgacaga tatttcactc ttaaagcatg ctaagcatat
     3421 tactgagctg cacttagagg gcaatcagat tgcaagcatt ccaaaggaaa ccttcagtca
     3481 aatgaccaat ctaaggttct taaatcttcg cagcaatgtg attacaaccc tagataagga
     3541 tacctttgct cataacagcc agctaaaaga gctctatctc tcaagcaact atatgccaaa
     3601 tctggaggaa ggactattta gaaatcttgg tcagctggat cagctagatc tgtcaaaaaa
     3661 tagaatcagc gtgattcgag atggtgtctt taatggtcta tctcgcttga cctccttggc
     3721 cttggctgaa aatatcatta ctgaattttc agaaaatgct ctagcttcac ttgataatct
     3781 aaacttcttt gatgtttctg aaaaccagtt gggcagcctg ccaagctcct tgagtaagct
     3841 aactaagctt tcttatatcg ttgccaatcg aaaccaggtt ttagatattg ctaatattga
     3901 ctttagtcat atgccaaact tattaaccgt tgacttggca tcaaatgagc taactaaaat
     3961 cccacaggga gccttcaagg ctaataagca gctatcaaag cttaatgtct ataataacct
     4021 tttaacgaat attagcgaag ctgattttgc agatctaaag gcattggatc ttgatcttaa
     4081 gtttaactgc ctaagtggcg ttagtgataa gcttagacag atcatgggaa caaataagct
     4141 aaacccacaa aagcaatttg ctaatctatc tgcgacttta aatcatcaag cgatgaccta
     4201 tcaccaaggg tttagcctgc ttgatttgta ttattgggag cagcagacac tctcaagcac
     4261 cgaagcagaa attagctctg ttgaggatta caataaacgc cttaaggcaa gctcgtcaga
     4321 catcattgcc ttattaaatg agcgttatgc tgactgggat attgtggtgc aattgcagaa
     4381 aaaaacatca accggtcaat atgtcaccgt tgatgagaga cgcttgaata acgatccaca
     4441 agatgagctt caaggctcct ttgacctaaa gggagcaggt gtttatcgtg ttcgtaaggc
     4501 tcttatcacc aaggaatttg ctaagaagcg tgagcatatt tatctgacct ctaatgatgt
     4561 tgaggtcaag gaggatcagc ttgcaggtag tgaccagtct aagggcttgg atattaataa
     4621 gcttgaagat ggtgtctact acatcaaggc aagcatgctt aaaaatgatt tgcagtcaga
     4681 atcaatgtct catcaggcta ttgaccaccg cgtcaaattg attgtgaata agggtgtcta
     4741 tagcctagag gtgaccttta agggcatgaa gatcggtaac ctgacagggt atctcggaga
     4801 gttgagctac tttgttgatg gctaccaaag ggatttgact ggcagaccgg ttggtaagac
     4861 agaaaaagca gaggttgtgt cctactttac agatgtcaca ggcaagcccc tgtcagacgc
     4921 ttatggcagc aattacccac aggtgttgag atttaggctg attgatcagg ctaaaaagga
     4981 tggcttggta cctcttcgcg tctttgtgcc aattatggac gctatctcta agggaacagg
     5041 cttccagaca gtctttatga agttggatct tcaaagcctg acaaaggata aggcacaatt
     5101 gccacactca gaggacaatc agggacatgg taccataggt gagctcttgc agcctcacac
     5161 aggtatcatt ggtggtcata caagtcctgc tattcctaat ttgaccaatc ttttgactaa
     5221 gaagtcagct gctccaagca gtaatgccaa ggaggacgct aagaccggta cagataagct
     5281 taagagcctg atttcttcac ataaggcgtc taaggctggt acaggcaagg cctctaagca
     5341 ggctgctaag actagagcca aagctaaatc taaggctgct aaacatagtc aggagcagat
     5401 gaaagctgat catcgcggcc atatcattat cggtctagca agctttattg tcatagcagt
     5461 tggtctcatt cttggtagga aaaaattatt ttaagtcagt agagagtctg tttgatgcac
     5521 taagagcttg gtttaatcgc ttgtagtcat caaggcttat caacgatacg taaaggcatg
     5581 cctgtttcta atgatttctt aagcttaccc ttggtaagtg aggaatgggt atgcttttcg
     5641 tatttgaggt gttataatag tcaaataaga gtaggtcttg gcctgcgtct aaatctatgc
     5701 cttatttgat tgtcgtaagg aaatgaagat cattaatgag gaacatatga taaagagatt
     5761 attcaaaaaa ttaatgggtg gcttggtggt attgctggtt tgcctagcag ctataggagg
     5821 taaggcctat gctgataagg gtgagcttta ttcctgtgtg attaggcgag attatcgtca
     5881 cccggtttca gggcaaattg aagatagcgg tggtgagcac gcttttgaga ttggccaagg
     5941 tatggtggaa ggaacagttt atagcaatgg tatgctagag gtaacctcgg ctggggattt
     6001 gtatctgacc tttcgcatga gtctagctga tttttcaggt aactaccaat tttgggttca
     6061 gccgggtggt acaggggctt ttcaggcggc agcctacagt gtcaccaagg ttggcactga
     6121 taccaatggc acaacaaagg atattgcgat tgctttgcct gatgtcaata cggttgttag
     6181 aggcagcatg tacgtagagc ctatgggcag agaggttgtc ttttacctgt caccatctga
     6241 gctacaagaa ggctacagtg gagatatggt agctagcttt gcagcaggag aagccaagac
     6301 ggatcatgcg gtgacagctc ctgcaaaggc agatgagaag aaagctccta gtaaaccgga
     6361 ctcaaaagac gccaagtcag ctcctaatcc ctcagcaagg ccagttggtc aatcaagcag
     6421 tcccaaaaaa cagtcaaatc cctctaagaa gggtcaggca gttggtttga gcacttcgct
     6481 agataaaagt aagcaagagt cgtcccaaaa gccagtaaat aatccattgc cagttctggt
     6541 ttactatgta ccaacagctc ttttgttgtc aggagccttg gtcttgttta taaagaaaaa
     6601 gagaaaaaac aatgaagaaa gtcattaagc ttattggatt agctgttttg tccttggtgc
     6661 tatctgcttg tgtggatcag caccctaggg cagagaaaaa ggctgataag gagagaattg
     6721 ttgccacctc tgtggctgtt gttgatattt gtgatcggct aagcctagat ttggttgggg
     6781 tctgtgacag taagctatac caattgccaa agcgttacga tgctgtcaaa aggatcggtc
     6841 tgccgatgaa tcctgatatg gaggttattg cttctctaaa gccaacgtgg atactcagtc
     6901 ccaattctct gcaaaatgat ttagagccta aataccagca attggatacg gaatatggct
     6961 ttttgaattt aactagcctt gaaggcatgt accagtcgat tgatgatttg ggggacttgt
     7021 ttgatcgcaa aaaggaagct aagcgcttgc gggctgatta tgaggagttt taccgggcct
     7081 ttaagaaaaa gcataaaggg caaaaaaagc ctagggttct tattttgatg gggcttcctg
     7141 gcagctatct gattgctaca aataaatcct atgttggtaa tctgcttgag ctggctggtg
     7201 gtgagaatgt ttatcactct gaggacaagg aatttttgtc tgccaatcca gaagacatgc
     7261 ttcagcagca gcctgagctg attttgcgta ctgcccacgc cattccagac aaggttaagg
     7321 acatgtttga taaggaattt gctgaaaatg atatttggaa gcattttgaa gctgtcaagt
     7381 ctcagcaggt ttatgattta gacaataccc tttttggcat gagtgctaag tttaactaca
     7441 aagaggcttt gaaccatctg tcacaaatct tttatggagc aaaggaagtc aagtaagatg
     7501 cagcaaggta gtcaatattc tgatcaagtc acagcagcaa gaaaaaggac cactagactg
     7561 gtctatatgg ttctattgct catgctgctg tttggtttaa tgctatatgc ggtctctgtt
     7621 gggggcttat ctgtttctta tcagaggatc tttaatggct tatttgtagc atatgattca
     7681 gaggtagccc ttatttacga tttacgcttt ccaaggattg tgattgcttt attggctggg
     7741 gcggggatag caacatctgg ggtcttgttt caggcgattt taaaaaatcc tatttcagat
     7801 ccggcgatta ttggggtttg cagtggggct agctttatgg tcttgttatc tagcctgctt
     7861 ttgccgcagc tcttgtttta tggtcctttg ttatcatttg tgggaggctg tgtttctttt
     7921 ttgatgattt ataccttgtc ctggaagaag ggcttgcagc cgatacgcat cattttgaca
     7981 ggaatagcta tcaacgcctt gtttttaggc ttgtctcgtg cgattactga tttttcaaaa
     8041 accagcaatc cctttgtcaa tgcgctgttg tcaggaaata ttagtcaaaa aacctgggca
     8101 gatgttggtg tgctgtggcc ttatacagtg cttggcctgc tgcttgcgat aggcctagca
     8161 aggcagtgtg atctactgct gctaaacgat ggcttgattc gtaatttagg cattgatagt
     8221 aattacctgc gcttaggaat ctcgttggtt gcggtcttac tagctgctgt ttccacctcg
     8281 attgtgggtg tggtgtcatt tttaggcctg attgtgccgc atattggccg ccttttagtt
     8341 ggcagtaagc atagctatct cattcctttt tctgccctgc ttggcgcctt tgtctttttg
     8401 ctggcagata ccttaggaag gcagttgtgt tatcccttgg agattagccc agctgttatc
     8461 atgagcattg tcgggggacc ttattttatt tatctgttaa ggaggtctga cgtgatatga
     8521 gtcatgagca aggcttgatt cgtgtagagg atttgtcctt tacttatcgt gataggccta
     8581 ttttagatag gctgagcttt accattccaa aaggcaagat aacgacaatc atgggggcaa
     8641 acggctgtgg caaatcaacc ctactaggtc tgctgactaa aaatatcccc gttaagtctg
     8701 ggcaaatttt cttagaggga caagctatta gctctattag tcttaagcag tttgcccaaa
     8761 aagtagccgt tgtgcatcag gataatcagg cggtagcaga tcttctggtg ggtgatttgg
     8821 tggctgtggc aagccaagcc catcggcgtt tttttaaggg atcaagtcaa gaggacgatg
     8881 acattgttgc ttgggcctta gaggtgacta atctaaggga attggccttt agggaaatgc
     8941 aggagctatc tggtggtgaa aagcaaaggg tctggattgc tatggcgctt gcccaaaaaa
     9001 caggtgtctt agtgcttgat gagccaacca cttatcttga tattaagtac cagctggaca
     9061 ttttagccct catcaaaaaa atcaatcagg agctaggaat gaccattatc atggtgttac
     9121 atgatattaa tcaggccttg gctgtttcgg attgtgtgct tgggctgcaa aaaggtgcca
     9181 tctatgccca aggcagtcca caggaggttc ttgatcaggc ttttgtggag gcggtttttg
     9241 gggtgagctt gccctttatt gaaaagcagg ataggcgatt tgttcttacc actttatgag
     9301 acaaataaaa aatgaatgat agataggaat aaggcgacga ttatatgaac gatacaactg
     9361 aaaaaatatc acgcgcaaag aaaaaaatgc ttttaaggcg tttaaaggag cgtattgctc
     9421 ctaagcgttt tttgctttat gtgtcggcct ttttatcttg gctgcaattt ttgatgcgtt
     9481 taatgagctt ttacttaatt gctaagcaat tcacagcctt tttagcaggt caagccctgc
     9541 aattgacaag gctgcttgtt atccttttga ttttaaatgc tgttggcttt ggcttggcga
     9601 tgattgcaaa gcagctgcag ggcctagctt cgcaatttgc gcgtgactcg ctcaagcaat
     9661 ccttttttga tgcctttatt gctatggacg ggcaatttga tcagcagtca acagaggctg
     9721 atgtgttaac ggttgcctca caagggattg atagcttgga tacctattat tcctattacc
     9781 tatcgcttgc aatgctaaca gcttttaatt gcacaacggt cttactgctt gtttttttga
     9841 tctatcctat agggggcttg gtctttatct tgtctttgcc cttgattccc atatccattg
     9901 ttgctatgca aaaacgctct aaaaggatca tgaaccatta ctggtcaacc tatatggacg
     9961 ttggcaatct atttatggac gatctcaagg ggctaaatac cctttattcc tatcaggcag
    10021 atgaaaggta tgaggaaagc tttgtcaata aggcagaggc ctttcgtaag gctaccatgc
    10081 agctcttggg ctttcagctg caagcggttg gctatatgga cgctgtcatg tatcttggca
    10141 ttggcttatc tggcttttta gcggttcagg ctctgtcagc tggtggtata tccttttttg
    10201 actttctctt ttttatcctg attgcaacgg aattttttgc ccctattagg gagcagggct
    10261 atggcatgca cctagtcatg atgaatacta aaatggcaga tcaaatcttt ggctttttag
    10321 atagcgttga ggctgttgac caagacaagg gagttgcctt accggccttt gatcgtattg
    10381 atattcaaga tttgtccttt tcacatgggg aaaaggcttt gctaagagac atcacgatga
    10441 ctatcaaaaa gggtgagcta acagctgttg caggtgtttc aggacagggt aagactagtc
    10501 ttgcacagct cctgttgaag cgctatcagg cagatagcgg tcagatattc cttggtgatg
    10561 tgacgattga tctggcttct aaacaggcca tcaatcagga aatactctac gtttctgacc
    10621 agtcaacgct gcttaatatg agtatttatg agaaccttgc tatggcagct cagctgacta
    10681 gaaaggagct gcttagctgg attgatgagc atggcatttt gagctttatt tactggctac
    10741 ctgatgggat tgataccatt gtaggtgaga atggctgtca cttatctgca gggcaaagac
    10801 agcaggtgat ttgtgctagg gccttattga gccagcgttc ctgttatatt tttgatgagg
    10861 ctacctcaag tcttgatgct gagaatgaag ctgctattca cagactgctt cagcaattgg
    10921 ctaaacaggc cattgtaatt gtcatcactc ataagatgaa atatttgaag caggctgatc
    10981 aggtgctctt tttaagccct gagcagtctg ctagcttggc tagcccaaga gagctttacc
    11041 gccatcattt ggcctatcgt caattagttg atacacaagt agaattggag gcaaatcttt
    11101 atggttaaga gtgattacag cacctaccgg ctagttttac gattgcttgc tatgatgaag
    11161 catttgctgg cttggatagc tctggcggtg atgtttgcag tgctgggctt tgtgcttacc
    11221 gttggcattc ctaccagctt agcctatctg ggcttagagg tgatggctgg tcatgctatt
    11281 acctttaaat ggctttatct atttgttgct atggcactgc taagggggct tgttcgttat
    11341 ggagagcatt attttgggca ttttgttgcc tttcatagcc tggcagcctt tcgcaggatt
    11401 gtctttaaaa agctaagagc actctcgccg gcacgcttag acagtcagga cagcgggcac
    11461 ctgttaaaga tgattggcga ggatattgag gccttggagg tcttttttgc ccacacgctt
    11521 gcccctattt gtacggcgtt tatttcagct agcttgatgg cctattacct ttggcaggtt
    11581 agctggaagt tagccttggg ggctattgtg acctatgtgc ttttggctgt tattattcca
    11641 gtgtattttt caaacgtcct tcaatcactg ctcaaaaagc aaaatgaagg gcgcagggct
    11701 tatgtgtcaa gctttttaga gagtctcaga tctgttaagg atttgctgca atttcaaagc
    11761 attgagaagc gctttaagct cttatccaat cagagcaagc atgttaatgc gcttgatcgt
    11821 caggtggcac aggctcaatt tttacaaatg gcgataacct ttttggctct tggcttgtct
    11881 attttgacct ttgcttatgt tactcttttt gagctgagtc agcagacggt gacgtttgct
    11941 ggtgggttgc tggcttttgt tgcctttaca gcctcctttg cacccttttt agaattgggg
    12001 cgtttgccgc ttggcttcaa gcgtgccatg aatgctgcta ggaatgtctt tcagctttta
    12061 gatgaagaag cgttagtaga taagggagat cagcgtattt cctcggtaac aaggattgct
    12121 gttgaggatc tgacctttgc ttatcccaag catcaggaga ctatttacca ccacttatcc
    12181 gtcgcttttg aaaagaaagg cattatcggt attcagggag agtcaggctc tgggaagtca
    12241 actctgatga agatcattat gaaatggtac aattggcaag ctggtcatat tttcctgagt
    12301 gaggttgaca gtcaaacgct aaatgctgct tccctacagg ctaactttgc ctatgtccca
    12361 cagaatgcgc agctatttca gcaaacactt cgtgacaata tcacacttgg tcgtaaggac
    12421 atttcagatg atgatatcat ggaacttgct gaggcctgtg gcatgaagga gcgtatccta
    12481 gcctgtgatg aggggctaga taccctagtg agaggatcag cagacttttc agctggtgaa
    12541 gcccagcgct tggaattgat gcgggctcta ttgaagcggg cggattgcta tatttttgat
    12601 gagccaacat caaacttaga ttcgctgaat gaagccatct ttattgattt gattaaaaag
    12661 cattgccggg gaatggtctt tttgatttca catcggccat ccaccttggc ctgtgcagac
    12721 cagctatttt gtgtgagaaa tggttttttg aaggaggtaa acaatgaaag ggttaaccat
    12781 taaagatatc atgacaacag gcgcctttgc cgccctctat ttcgtttgtg tggggctagg
    12841 agccatgctg agcattctgt ttgatcgctc aggcaatatg ctctatgcgc cagcctttgc
    12901 ggccttgctt ggcgggccag tttatatgct attaatcgct aagctgcaga cctttggacc
    12961 gataagccta gtaggaatta ttatgggaag ctttttcttt ttgacaggtc atttttttgc
    13021 ttcaatgcta ccagctattc tttttggctg tttggcagat ggcatagccc ttttaggaaa
    13081 atatcaatct agactagtga atctcttgtc ttatcttgtt tttgcctttg ttaacagtgg
    13141 tcctattatt ttaatgtggc tgttgaagga cgcctatatc cagagtcttt tagcgcgtgg
    13201 taaggacatg gcatatgtta accgtatcat gtatgacttt accgttgcaa atgtcagctg
    13261 gtttgttggt gttgtccttc tttgtgcctt agtaggtggc ctttttggtc aatacctgct
    13321 gaaaaagcat tttgctaagt caggaatgct tttatgaggc ttgatgttcg cacaaaattg
    13381 ctcctgttaa ttctagccaa tgcctgcttc ttttttcgga ttgatggctg gctggggacg
    13441 atgattatag gtgttttgct tggcattttg ttttggcttg gtcaagggcg tctggcaatc
    13501 ggtatgacac tgctctatgc cttactgctt gctttgtctg tattgccgct tcatgtgctg
    13561 ccagcctatc tgtttaggct gctgagcttt gcagctgttg ctggtcaatt gctttaccca
    13621 tctgtgcttg ctgctttgat ttttgtcaag acaacgactg cctacgagct tgtgcatggg
    13681 ctgcgaaaat ggcatgtgcc agaggtttgt ctgttgactc ttgctgtcat gctgcgtttt
    13741 ttacctaaga tcaggcaaga aggaaagatt attcggcaat ctctgaaaat caggggcatt
    13801 ttcttggaca gctgggctat tgtcagacag ccaaggcggt atatggagta tctcttggta
    13861 ccgctgttga tgtcattgct gagaagtagt caggacttaa ccattgctag cctaacaaaa
    13921 gggctagcaa tcaaaaaggg agcaagtgag tgcttcgtat cacatctatc atggaaggat
    13981 tggggggtac agatttggat atttgtgacg atagcctaca tggttctcca gtgatcaagg
    14041 caaagcagct gcagttttcc tataccaatc gtaggcagac tgcctgtgag ctcagggatt
    14101 gtcagataga ggcaggtcaa tttatcgtgc tttgtggtca gtcaggctca ggcaagtcaa
    14161 cctttcttaa gctgctcaat ggcttgattc cagactattt ttcaggacaa ttacaaggaa
    14221 gtctgaaagt actgtctcat caggctggtc aggctagtgt tgaagtgctg tcaaggcagg
    14281 tttcctctgt ctttcaaaac ccagccagcc aatttttcta tcgtgaggtc aagcatgagc
    14341 ttgtttttcc ttgtgaaaat caaggcttag agccagctct tatccttgag aggctggata
    14401 ccttggcagc tgattttgac atcaaggact tactagaagc agatatgctt aagctatctg
    14461 gtggtcaaaa gcagcgggtg gctattgcag cagctatcat gcaagggaca gctatcatgg
    14521 tttttgatga gccaacagcc aatttggacc atgctagtgt agcagcggtc aaggcttatt
    14581 taaagcagct taaggctgct ggcaaaacca ttattgtcgc tgagcaccgc ttgcattatt
    14641 tgctggattt ggcagaccat ttttactatt tttcagctgg taggctagag cgcgtattaa
    14701 gccccaagga tctgctagct ttgccagatc aggaacgtga ggagctagga ctaagacgat
    14761 gtgagttgac tgctgtgact aaggctttgc gggcaaaaac tgtttttgag cattatgatc
    14821 cagagcatgc cttgcaaatc aagcagctag aggtcaaggc aggcagcagg gttttgtatc
    14881 acctcaatca gctcagcttt ggtgcagggc aaatcactgg cattaccgga gctaacggtt
    14941 tgggaaaatc gcagttggct ttatatctgg caggtatttt tgaagcaaaa gaggccaaga
    15001 tcagctatct gggtgtcacc ctgcctgcta aggacaggct ttcaatcaca agcctagtgt
    15061 tgcaggacgt tgggctacag ctattttcgg agacggtaga aaaggagctt aatctaggtc
    15121 atcatagaca tcaggctact gatgatttgg tgaataggct tgggctttct cagcttctag
    15181 acaagcaccc tgccagccta tcaggtggtg agcagcaaag ggtgatgatt gctgccagcc
    15241 tcttgtctga caaggagatt gtcattcttg atgagccaag cagtggctta gatctgctgc
    15301 aaatgcaggc tctggttagt cttttaaagg agctaaagca gcaaaaaaag gtagtgattg
    15361 tcatctctca tgacgaggaa ttactggatc aagcctgtga tagtatctat cagttgagca
    15421 ggtaaaggcc tagccttgct caagcggtct ggtgctgtat tggtgatggc tttatcgctc
    15481 cttggagcag caggtgttcc tgcttgatct gataaccact agctgcgatt gaccaatcac
    15541 aagccgccaa ctcttgacaa gctagcagta gctatcacaa ttctagggca tatcttggcc
    15601 tagcaagcag tgctgtattg tttatatgcc actcttcatc ttttagttag gccgtcctag
    15661 cggccgcact aagggtgtgt taggatcggc taatacctca aggcatctac agtaagaaaa
    15721 cgagcctctt cctttttgga gaggctcttg atttttgata taataatgaa aaagaaagcg
    15781 aggttgagat gctgttaaag agttcgattg ctaatttgaa gggtcttggt ccaaagtcag
    15841 ctgagaaatt tcaaaaatta ggcatttatc agatcaagga cttgctactc tattatcctt
    15901 ttcgctatga ggattttaaa agcaagtcag ccttagagct tttagatggt gaaaaggctg
    15961 tccttacagg tagagttgtg actccaccaa gcgttcaata ctatgggttc aagcgtaatc
    16021 gcctgagctt taaattgaag cagggggagc ttgtgattag tgtcagcttt ttcaatcagc
    16081 cttatctgct tgagaaaatc gtcttggatc aggaagtggc tatctttggt aggtgggatc
    16141 aaaaaaaagc agccttgaca ggtatgaaat tgctcatgac cttagaagat gatttgcagc
    16201 cagtttatca tgtggcgcag gggatcagtc aacccaccct gattaaggcg atcagatcag
    16261 cctttgatag cggtgcctta gctcagctgg aagaaaattt accagagccc ttgattcaga
    16321 aataccgcct gctgccgaga caagctgctg tttatgccat gcattttcct aaacatatgg
    16381 aggattataa gcaggccctg cgccgtataa aatttgaaga atttttctat tttcagatga
    16441 atctgcaggt tttaaagctt gctaacaagg cagagggcaa tgggttagcg attccttttc
    16501 atcagcaggc agtggcaaaa aagattgctg ctttgccctt ttcactgacc agagctcaac
    16561 aaagaagcct ggaggaaatc ttagcagata tgacctcagg ggctcatatg aaccgtctgt
    16621 tgcaggggga tgtcggctct ggcaagacag tgatcgcaag ccttgccatg tatgctgccc
    16681 aaacagcggg atttcaatcg gcactcatgg tgccaactga gattttagct gagcagcatt
    16741 acgatagtct ttgtcagctc tttccagatt tgtctattgc cctgttgaca tcgggtatga
    16801 aagcagctga aaaaagagca gctttatcgg ctattgctga tgggtctgtg gatatgattg
    16861 ttgggacgca tgccttgatc caagacgcag tgacctatca taagctaggg ctggtgatta
    16921 ctgatgaaca gcaccgtttt ggggttaatc agcgtcgctt gtttcgcgaa aaaggcaaca
    16981 atccagatgt tttgatgatg acagctactc ccatacctag aaccctagcc ataactgcct
    17041 atggtgagat ggacgtttcc attattgatg aattaccggc agggcgaaag ccaatcatca
    17101 ctcgctgggt caagcatcgg caattagata gtgtgctggc ctgggtaaag accgagcttg
    17161 ctaaggggac acaggcctat gttatctctc ctttgatcga agaatctgaa actctagatt
    17221 tgaaaaatgc ggtagcttta gaggctgagc tgaaggatta ttttaaagct tcagctagtg
    17281 ttgccttgat gcatggcaaa atgaaggcag acgacaagga gatgatcatg cagcgcttta
    17341 aggctaagga gattgatgtc ttggtgtcaa caaccgttat tgaggttggt gtcaatgtgc
    17401 caaatgccac catcatgctg atcatgaatg ctgaccgctt tggccttagc caattgcatc
    17461 agttgcgtgg tcgtgttggg cgaggcagca agcaatccta tgctattttg gtggcagatc
    17521 ctaagacaga ctcaggcaag gagcgtatga ccatcatgac aacgactaat gatggctttg
    17581 tgctggcaga ggctgacctc aagctgcgtg gctcaggaga gatttttggg acccgtcaat
    17641 caggtttgcc agagttcaaa acagctgata ttgtagagga ttatcatatc ctagaggagg
    17701 caagacgagt cgctgctgag attgttgcag ctaaggattg gcagctggac cctagatggg
    17761 ctccgatttt ggctaatctt cgtgtcgctg atcagtttga ttagatgtga ggctgacttg
    17821 ctggacagag ctaatataaa aacacgacaa gaggttctta gctgaccgag tcgtgctttt
    17881 tgtgctatag atgaggagta gtagcctgtg attataggag agcttagcct tcgatataat
    17941 ccttcagctc ttgacctgta agcccagcgt tgagggcgat gagcaatttt aacctggcct
    18001 taggggcatt tagctccttg acaaacataa caccagccct ttttaagctg gcaccacctc
    18061 cgcgataagc ataaactggc tctgctatgc cattgaagca gcgcgagacc aagacaacag
    18121 gaatcccaga ggcgattaat ttttcgagct cagatactgc taggggagga acatttccag
    18181 cgccgagggc ctcaatcact agtccctgaa tcctatcagg tgtcaaaagg cttaaaatac
    18241 ttccatctcc cataccagca taggccttga taatcggaac tgtgccagaa atatgacgaa
    18301 gctcaaagcg aacccttggc tcagcagtct taaagaacag taaatcgtcc ttcatgacga
    18361 ctcccaaagg gccatgagtc ggtgtttgaa aggtcgaaac attggtggta tgcgttttgg
    18421 tgacatactt agcggcatga atttcatcat tcatcacaac cagcaccccc ttgcccttgg
    18481 ctttctcatg gctggctacc ctaagcgctg ttaggtagtt atagatacca tcgcttccaa
    18541 tctcgttggc cgagcgcata gcacctgtga taacaatagg caactctaca ggcagcacca
    18601 ttgtgtctag aaaataagca gtctcttcta aggtatctgt accatgtgtg atgaccactg
    18661 catcaaactg actagccctt tgttgaatgt aatgatacat cttgagcatg tggtgagggg
    18721 tgatgtgcgg gcttggcaga tttaaaaaat ccacaacagt taggtggata tgctccaggc
    18781 taaggccaac ctgattcatt ggattgtttt gatttgggct caccttgcct gcttcatcag
    18841 cctgcattga aatggtgccg ccggtatgta agacgaggat ttccttcatt tgatactcat
    18901 acttctttca atttatgata taatttattt tatcacaaat agaagagaga acagaaggat
    18961 ttgacaataa aagcagtctt tttcgacatt gatggaaccc tgcttaatga tcgaaaaaat
    19021 gttcaaaaaa cgacgcaaag ggctattcag caattaaaaa aacaaggtat tatggttggg
    19081 ctggcaactg gtcgtggacc tgcttttgtg cagccctttt tagaaaattt tggcttggat
    19141 tttgcagtga cctacaatgg tcaatacatt ttgacacgag acaaggtctt gtatcagaac
    19201 cagctgccaa agtcaaccat ttataaaatc attcgctatg ctagcgataa aaagcgcgag
    19261 atctccttag gaacagcttc aggtcttgct gggtctcgga tcattgatat gggaaccagt
    19321 ccatttggtc agatggttag cagtattgtg ccaaggagtc tggtcaagac ggttgagggc
    19381 agctttaaaa acctcatcag acgctttaag ccgcaaagct tcagcaatct tgttaccatt
    19441 atgagagagc cgatttatca gattgtcttg gttgcttctg ttgatgacac ccaaaaaatc
    19501 aaggaaagat tcccgcatat caaggtaacc agaagcagcc cttattcctt agatttgatt
    19561 tctagcgggc agtctaaaat caagggcatt gaacgcttgg gcgagatgtt tggctttgag
    19621 ctctcagagg tcatggcctt tggcgactct gataatgact tagaaatgct ctcaggcgtt
    19681 ggtgttggtg ttgcgatggg aaatgctgag gcagtggtta aaagcggtgc tcactttaca
    19741 acagcttcaa ataacaatga tggtatctct aaggcgctgg cgcattatgg cttgattcat
    19801 tttgatgtgg aaaaaagctt taaaagtcgc gatgataatt tcaacaaggt caaggatttc
    19861 caccgcctga tggacggaga cacgattgaa acaccaagag gctattcctt aaaggaggct
    19921 ggctatcgag cagattttaa ggtagaggaa cttgtggaat ttctttatgc agccagtcaa
    19981 ggggataagc atcgcttttc tcaggctttg atagacctcc atgctgccct tgataaggca
    20041 gctaagaagg tgcaggccaa ggagcaccca gagtcacccc tggttgggca ggttgatgct
    20101 ttgacagatc tgctttattt tacctatggc tcatttgtat tgatgggagt ggaccctcag
    20161 cccatttttg agaccgtcca tgaagccaat atggggaaaa ttttccctga tgggaaagcg
    20221 cattttgatc ccataacgca taaaattcaa aagccagatg actggcagga gcgctatgca
    20281 ccagagtcag ccatcaaaaa agagttggac aagcagcttc aaaaatcatt gcagcgcttg
    20341 gaaaaataag gctgtcttta ttttagaggc attaaaaagc accttgagct gtgagttgat
    20401 ctcctagctg ttaagcattt ggcctaacac ttggggtcac ttcacttatt agctcagggt
    20461 gctttttgat gtagactaga caccctcaat aaaagggccc ttaagtctag ctagtggtaa
    20521 ttagtatatg agagcagtag tcctttagta gccttgtgag ctgaggctaa gggctaggta
    20581 tggttacttc acttaggctg caaatgcttc tgacagctga gagaattcgt cttgctacag
    20641 ggttttgtca tgctctcgaa ccactaatag gtcaaccttg gcatgacgaa ggatatattc
    20701 agatgatgat ccaatcagca accgctcaaa ggtgttaagc ccagttgccc caaccataat
    20761 caaatcaacc tcttctttgt cagggatatc gtgcgctaat agcgttttgg gattgccaaa
    20821 ttcaatcacc tgcttgacct cagtcagccc tgcctcgcgt gcttgttttt caaaatcccc
    20881 caagacctct ttagc
//
LOCUS       DARYJX010000039        20403 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYJX010000039 DARYJX010000000
VERSION     DARYJX010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20403
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(85..1350)
                     /locus_tag="TU257_001555"
     CDS             complement(85..1350)
                     /locus_tag="TU257_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL0834556.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TU257_001556"
     CDS             complement(1364..2221)
                     /locus_tag="TU257_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834557.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TU257_001557"
     CDS             2564..3856
                     /locus_tag="TU257_001557"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL0834558.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TU257_001558"
     CDS             complement(3971..4744)
                     /locus_tag="TU257_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL0834559.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TU257_001559"
     CDS             4869..5615
                     /locus_tag="TU257_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0834560.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TU257_001560"
     CDS             5630..6610
                     /locus_tag="TU257_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL0834561.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TU257_001561"
     CDS             6849..7169
                     /locus_tag="TU257_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0834562.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TU257_001562"
     CDS             7194..7502
                     /locus_tag="TU257_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0834563.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TU257_001563"
     CDS             7513..8817
                     /locus_tag="TU257_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0834564.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TU257_001564"
     CDS             9098..11515
                     /locus_tag="TU257_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL0834565.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TU257_001565"
     CDS             11530..12198
                     /locus_tag="TU257_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0834566.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     VEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TU257_001566"
     CDS             12323..13414
                     /locus_tag="TU257_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL0834567.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TU257_001567"
     CDS             13921..14973
                     /locus_tag="TU257_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL0834568.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TU257_001568"
     CDS             15002..15580
                     /locus_tag="TU257_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0834569.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TU257_001569"
     CDS             15779..16687
                     /locus_tag="TU257_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834570.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TU257_001570"
     CDS             complement(16923..18269)
                     /locus_tag="TU257_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834571.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19309..19413)
                     /locus_tag="TU257_001571"
     CDS             complement(19309..19413)
                     /locus_tag="TU257_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0834572.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19793..20308)
                     /locus_tag="TU257_001572"
     CDS             complement(19793..20308)
                     /locus_tag="TU257_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL0834573.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5781 a         4094 c         4555 g         5973 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggtaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aataactcct tataactatt attcatttta
    18301 attaattaac cagttaacta tatcaatcta tcaaaaaaaa tatagtatgt caacctctta
    18361 aagtgattta atcagaacaa acgtatgaag aaaatcattt ggtgaaaaag aagcttattt
    18421 tagctgaaat agatccatta taaaagaggt gtcgtgaagt aactcaatat tcacctattt
    18481 ttgtcgcaag tattctaata ggaatagaaa aagggcagtt gcttgcaaca actacccaat
    18541 gtaaaaccgt taaagacggt gacagaaaat aactgttaac tgaactacct caaaagttaa
    18601 accaaagatc taaccgttgg atgttggttt gtagagcggt tattttttta ttgttatgtt
    18661 tacaacgact aagctcatca gtgtaaggga aagggacttc catattaaga agtatatata
    18721 catcctagat gagacgtgta atgaatgggt tgaacaaata gttgcttaat tttgggataa
    18781 gggttataat aaaaatagaa aaagggcagt tgcttgcaac aactacccaa tgcagaaccg
    18841 tttgagacgg tggctggttt tatagttaaa agataaccgt taactcgcca aagttaagga
    18901 cggttatttt ttattgtcat ctttgaagat ttgatagcac aagctgataa gcgcaatagt
    18961 aaagctacta aagcctaaaa ggatttatac cacttcaaaa gctgtcaatg ctttgactca
    19021 tcctttctgt tagattttga tgaactgccc ataggcctca cctacctttc agaaataaga
    19081 gccaccgtct taacctttct gctttatcat tatagcatat tgttattaag gttgactatt
    19141 cagactcgtc taaagaagtg taatagttgc ttaattttgg gataagggtt ataatgaaaa
    19201 tagaaaaagg tagttgctcg acacaactac ccatgcagaa ccgtttaaga cggtggcatg
    19261 ttttatgtta ttaaaaaata accgttaact cgccaaagtt aaagacggtt attttttatt
    19321 gtcatctttg aagatttgat agcacaagct gataagcgca atagtaaagc tactaaagcc
    19381 taaaaggatt tgtaccactt caaaagctgt caatgctttg gctcctcctt tctgttagat
    19441 tgtgatgaac tgcccatagg cctcacctac ctttcagaaa taagagccac cgtcttaact
    19501 tttctgcctt tttattatag cataccctat ctctgattga ctagcttaag aaggagggga
    19561 tgtgatttgg atacaaattt ttgttaactt ttttaaagtc tccaaatgat ttaaaaaaat
    19621 gatattaatg ctctaagtaa gaatattaat aatatggttt taccacttat tgtatgaggt
    19681 atcatttcta aagagttatt tttcagacag aaggcttgtt aaagcaaaca gaagcaatac
    19741 taaaggcatt agatgataat caaggccttt ttcatgtctt aaaatgagta tactagctgt
    19801 cgtgttggat agaattcata taatgattta actgcttttg attttttaaa acgattgttt
    19861 tatgaggata ttgtttaata actgctttat agttatttaa attatttttt gagcgtccgt
    19921 ctaacagaat ccatttcata aattcaacat caaatttttc attacagttt tcagccatat
    19981 caggacgtgt ttgtccccta tattttaaat atcgcttaaa agctcggtaa aaacaattaa
    20041 atctattaaa gttaaaatat ataatgtgat cagcctctct catacgctct tcataaagac
    20101 agcttgaata attaccttca ataatccaat gtttttgtga cataaatgtt gatatatcag
    20161 agaccatttg actaactgtt cgctcttgcc agtttgatgc aaaatgaatt ttgtctaaat
    20221 gaagtacagc acaattgtag tgttgaccta aaacatttgc taaagtcgac tttccagaac
    20281 cactatagcc aattattaca attttcaatc tttgtctcct ttgtcaatgc tgtactttga
    20341 cttatattat agcataaaga atatattttg gggacaaatc ctctttagac aagcaaaaaa
    20401 gcc
//
LOCUS       DARYJX010000040        20022 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYJX010000040 DARYJX010000000
VERSION     DARYJX010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20022
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1230
                     /locus_tag="TU257_001573"
     CDS             <1..1230
                     /locus_tag="TU257_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0834574.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TU257_001574"
     CDS             1242..2744
                     /locus_tag="TU257_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0834575.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TU257_001575"
     CDS             2725..4302
                     /locus_tag="TU257_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL0834576.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TU257_001576"
     CDS             4304..4510
                     /locus_tag="TU257_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834577.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TU257_001577"
     CDS             4507..4926
                     /locus_tag="TU257_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0834578.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TU257_001578"
     CDS             5123..5392
                     /locus_tag="TU257_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834579.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TU257_001579"
     CDS             5428..5595
                     /locus_tag="TU257_001579"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834580.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TU257_001580"
     CDS             5777..6400
                     /locus_tag="TU257_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0834581.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TU257_001581"
     CDS             6411..6791
                     /locus_tag="TU257_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL0834582.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TU257_001582"
     CDS             6794..7843
                     /locus_tag="TU257_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL0834583.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TU257_001583"
     CDS             7854..8120
                     /locus_tag="TU257_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834584.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TU257_001584"
     CDS             8130..8483
                     /locus_tag="TU257_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0834585.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TU257_001585"
     CDS             8480..8788
                     /locus_tag="TU257_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834586.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TU257_001586"
     CDS             8769..9134
                     /locus_tag="TU257_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0834587.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TU257_001587"
     CDS             9131..9520
                     /locus_tag="TU257_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0834588.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TU257_001588"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TU257_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TU257_001589"
     CDS             10183..10542
                     /locus_tag="TU257_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL0834589.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TU257_001590"
     CDS             10584..10913
                     /locus_tag="TU257_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834590.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TU257_001591"
     CDS             10930..14184
                     /locus_tag="TU257_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0834591.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TU257_001592"
     CDS             14216..14995
                     /locus_tag="TU257_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL0834592.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TU257_001593"
     CDS             14992..17049
                     /locus_tag="TU257_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834593.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TU257_001594"
     CDS             17049..17756
                     /locus_tag="TU257_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0834594.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TU257_001595"
     CDS             17758..18372
                     /locus_tag="TU257_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834595.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>20022
                     /locus_tag="TU257_001596"
     CDS             18383..>20022
                     /locus_tag="TU257_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL0834596.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLLNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT         6745 a         3508 c         4504 g         5265 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg agcatcgtgt
    19381 gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta agctagcgat
    19441 ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct cagcgattaa
    19501 tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg gtaatacgac
    19561 cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag ccgatcaaat
    19621 tattggtggt tcgattgacg ctgctaagat tagagtgatc aatcttaacg ctagcagcat
    19681 tgtcggctta gatgctaact ttatcagggc taaaatcgaa catacgatta caagtttgct
    19741 tgagggtaaa gttatcagag ctcgcaacgg agcgatgatg attgacttgt taaactctaa
    19801 aattgacttt aacagcaacg ctaccattaa ctttaataac aaggacaatg cgcttgtacg
    19861 taaagacggt acccacacag cctttgtgca ttttagcaat gccacgccaa aaaattatac
    19921 aggtagtgcg ctttacgcct cgatcgggat aacctcgtca ggtgacggga ttaacagcgc
    19981 gtcgagcggt cgtttttgcg gtgctaggtt ttttaggtac gc
//
LOCUS       DARYJX010000041        19007 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYJX010000041 DARYJX010000000
VERSION     DARYJX010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19007
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            71..1321
                     /locus_tag="TU257_001597"
     CDS             71..1321
                     /locus_tag="TU257_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL0834597.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1430..2311
                     /gene="truB"
                     /locus_tag="TU257_001598"
     CDS             1430..2311
                     /gene="truB"
                     /locus_tag="TU257_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL0834598.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2325..3257
                     /locus_tag="TU257_001599"
     CDS             2325..3257
                     /locus_tag="TU257_001599"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL0834599.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3300..3704
                     /locus_tag="TU257_001600"
     CDS             3300..3704
                     /locus_tag="TU257_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL0834600.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3706..3984
                     /locus_tag="TU257_001601"
     CDS             3706..3984
                     /locus_tag="TU257_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL0834601.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            3974..4750
                     /locus_tag="TU257_001602"
     CDS             3974..4750
                     /locus_tag="TU257_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL0834602.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4767..6074
                     /locus_tag="TU257_001603"
     CDS             4767..6074
                     /locus_tag="TU257_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL0834603.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6212..7078
                     /locus_tag="TU257_001604"
     CDS             6212..7078
                     /locus_tag="TU257_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL0834604.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7089..8024
                     /gene="pstC"
                     /locus_tag="TU257_001605"
     CDS             7089..8024
                     /gene="pstC"
                     /locus_tag="TU257_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0834605.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8014..8901
                     /gene="pstA"
                     /locus_tag="TU257_001606"
     CDS             8014..8901
                     /gene="pstA"
                     /locus_tag="TU257_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0834606.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8918..9721
                     /gene="pstB"
                     /locus_tag="TU257_001607"
     CDS             8918..9721
                     /gene="pstB"
                     /locus_tag="TU257_001607"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0834607.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9735..10493
                     /gene="pstB"
                     /locus_tag="TU257_001608"
     CDS             9735..10493
                     /gene="pstB"
                     /locus_tag="TU257_001608"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0834608.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10564..11217
                     /gene="phoU"
                     /locus_tag="TU257_001609"
     CDS             10564..11217
                     /gene="phoU"
                     /locus_tag="TU257_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL0834609.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11451..13988
                     /locus_tag="TU257_001610"
     CDS             11451..13988
                     /locus_tag="TU257_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL0834610.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14407..15081
                     /locus_tag="TU257_001611"
     CDS             14407..15081
                     /locus_tag="TU257_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834611.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15074..16384
                     /locus_tag="TU257_001612"
     CDS             15074..16384
                     /locus_tag="TU257_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0834612.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVSQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16769..17188
                     /locus_tag="TU257_001613"
     CDS             16769..17188
                     /locus_tag="TU257_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834613.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17185..18378
                     /locus_tag="TU257_001614"
     CDS             17185..18378
                     /locus_tag="TU257_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834614.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITAAHAKQPATVFN
                     APSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKAGIG
                     RHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTEYRLLKKKYVASNGISSSEE
                     FYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEALHQKTRDMPFFVSELSWAE
                     LEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAAIDQKL
                     GCDFS"
     gene            18375..18767
                     /locus_tag="TU257_001615"
     CDS             18375..18767
                     /locus_tag="TU257_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834615.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            18787..>19007
                     /locus_tag="TU257_001616"
     CDS             18787..>19007
                     /locus_tag="TU257_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834616.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRG"
BASE COUNT         5704 a         3549 c         4309 g         5445 t
ORIGIN      
        1 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
       61 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      121 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      181 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      241 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      301 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      361 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      421 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      481 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      541 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      601 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      661 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      721 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      781 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      841 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      901 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
      961 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1021 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1081 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1141 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1201 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1261 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1321 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1381 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1441 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1501 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1561 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1621 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1681 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1741 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1801 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1861 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1921 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     1981 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2041 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2101 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2161 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2221 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2281 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2341 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2401 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2461 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2521 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2581 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2641 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2701 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2761 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2821 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2881 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     2941 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3001 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3061 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3121 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3181 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3241 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3301 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3361 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3421 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3481 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3541 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3601 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3661 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3721 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3781 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3841 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3901 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     3961 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4021 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4081 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4141 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4201 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4261 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4321 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4381 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4441 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4501 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4561 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4621 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4681 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4741 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4801 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4861 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4921 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     4981 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5041 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5101 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5161 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5221 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5281 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5341 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5401 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5461 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5521 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5581 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5641 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5701 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5761 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5821 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5881 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     5941 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6001 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6061 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaatttaaat aaaacttctt
     6121 ccaaagcatt gttagatatg ttaatataaa gaatatgctg aagcttaatt cttcgctata
     6181 aacctttatt tttatgaata ggaatagaat aatgaaatcg aaaaagaaat tctttttgtt
     6241 aagtctttta gccttgtcgg ctttcttttt gtcagcctgc tcaagctgga ttgataaggg
     6301 agaatccata acagcggtag gctcaacagc attacagccc ttagtagaag ccgcagctga
     6361 tgagtttgga agcaataacc tcggaaaatc tgttaatgtt caaggaggcg gctctggcac
     6421 tggcttatca caggtgcagt caggtgctgt tcaggtaggc aatagtgatg tctttgcaga
     6481 agaaaaggac gggattgatg ctgctaagct tgttgatcac caggttgccg tagcaggact
     6541 tgctgtcatt gccaatccta aggtcaaggt atctaatctc acaagcaagc agctacaaaa
     6601 gattttctca ggtgaatata ccaactggaa gcaggttggt ggacaggatc ttgctatttc
     6661 agtgattaat cgagcggcaa gctcaggctc acgtgctacc tttgatagtg tcatcatgaa
     6721 gggtgttact gctaagcaaa gtcaagagca ggattctaac ggtatggtta aatcaattgt
     6781 gtctcagaca ccgggggcca tttcttactt atcctttgcc tatgtggatt cgtctgtaaa
     6841 atcattacga ttgaatggct ttaaggccaa tgccaaaaat gtagcaacca atgattggcc
     6901 catctggtcc tatgagcata tgtataccaa aggcaagcca gacggcttaa ccaaggaatt
     6961 tttggattat gtgctatcag atgaggtcca aaaaaccatt gtgacacata tgggttatat
     7021 tgctatcact gatatgaagg tcgtcaaatc ctatgatgga aaagttacag ataaataatg
     7081 ggggaattat gaaaaatcag gaattagcta agcaattagc ctcaccatca aaaaattcac
     7141 gacttgaagc atttggtcgt acgattacct ttttttgcct cgccttaatt gtttttatcg
     7201 ttgcaatgat tttacttttt gtggctcaaa agggcttgtc tacctttttt gtaaacaagg
     7261 ttaatctttt tgatttccta tttggtacag agtggcagcc tagcgttaaa aatgctgccg
     7321 gtgttcctta tcttggagct cttccgatga ttgctggatc gtttttagtc acgattttat
     7381 cagccttggt ggcaacacca tttgccattg gggcagcagt atttatgact gaaatttcac
     7441 ccaagtacgg ggcaaaacta ttacagccag cagttgaatt gcttgtaggt atcccgtcag
     7501 ttgtttatgg ctttattggc ttgcaggttg ttgttccttt tattcgttct atttttggtg
     7561 gaacaggctt tggtatccta tcaggggtct gtgtcttgtt tgtcatgatt ttaccgacgg
     7621 ttacctttat gacaacagat agtctgcgcg ctgttcctcg tcattatcgt gaggcttcta
     7681 tggctatggg ggctacacgt tggcaaacca tttggcgagt ggttttaaat gcggctcgtc
     7741 ctggtatttt tactgctgtt atttttggta tggctagagc ctttggtgag gccttagcca
     7801 ttcaaatggt tgtgggaaat tcagcagtca tgccggcttc actaaccact ccagcggcta
     7861 cattgacctc tgtattgact atgggaattg gtaatacagt tatgggaact gttcaaaata
     7921 atgtgctatg gtcattagcc cttgtcttat tgctgatgag tctagctttt aattcccttg
     7981 tcaaattaat tacgaaagag agaaagagaa attatgaacg ctaaaaaggt tgataaagta
     8041 gcaactggta gcttgtatac tattgctgga attattgtag ctattttagc ttccctaatt
     8101 ctgtttattc ttgtgcgtgg cctacctcac atcagctggt cgtttttaac agggaaatca
     8161 tcgtcctatg aagctggtgg aggtattggg attcagcttt ataattcatt tttcttgctg
     8221 gtagtaacct tgattatttc cattccccta tcaacaggtg ctggcattta tttggccgaa
     8281 tacgctaaaa aaggacctgt gacaaatgtg attagaacct gtattgaaat cctatcctca
     8341 ttgccatctg ttgtggttgg attgtttggc taccttattt ttgttgtaca gtttgaatat
     8401 ggcttttcta ttatatcagg tgcccttgct ttgacggtat ttaatcttcc gcaaatgaca
     8461 agaaacgttg aggatagctt gctgcatgtg catcatactc aaagagaggc agggctagcc
     8521 cttgggcttt cacgctggga aacggttttt catgtggtta ttccagaggc cttgccaagt
     8581 attgtgacag gtattgtttt ggcttcaggt cgtatctttg gtgaagcagc tgctcttatc
     8641 tatactgcgg gtcagtctgc cccagcgctt gattggtcaa attggaaccc tttgagcgtg
     8701 acaagcccta tttcaatttt ccgtcaatct gaaaccctag ctgttcatat ttggaaggtc
     8761 aatagtgaag ggacaatccc tgatgcaaca cttgtttctg ctggtagtgc agcggtgttg
     8821 ttgattttta tccttatttt caatctatca gctcgcttta ttggcaagcg tattcatgct
     8881 aagatgacag cagcaaaata agacattgga gagattcatg acagaatata attggaacga
     8941 acgtcatatc attacatttc cagaagaaac gattgcccta gctactaagg atctgcatgt
     9001 ttattatggt agcaaggagg caatcaaggg gattgatatg caattcgaaa aaaataaaat
     9061 tacagcccta attggaccct caggctgtgg caagtcaacc tatctgcgca gcctcaatcg
     9121 catgaatgac accattgata ttgctagagt aacaggtgaa attttgtatc aaggcattga
     9181 tgtcaatcga aaggacatga atgtgtatga aatccgtaag cacctaggaa tggtctttca
     9241 aaggccaaat ccatttgcca agtctattta taaaaacatc acctttgctc atgaaagagc
     9301 aggagtgaga gataaaaggg ttttagatga gattgtcgaa acctccctca agcaggctgc
     9361 actatgggat caggtcaagg acgatcttca taaatcagcc tttacccttt caggaggtca
     9421 gcagcagcgc ttgtgtattg ctagggctat ttcggttaag ccggatatct tgttgatgga
     9481 cgaaccagct tcagcccttg atcctattgc aaccatgcag ctagaagaaa ccatgtttga
     9541 gttgaagaag gattacacca ttattatcgt tactcataac atgcagcagg ccgctagagc
     9601 aagtgattac actgctttct tctatttggg tgacttaatt gaatacgata aaacgcgtaa
     9661 cattttccaa aacgctacct gtcagtccac aaatgattac gtctcagggc actttggtta
     9721 gaaagaagga tatgatggca gaacctattt tacaaatcag agatctttct gtttactata
     9781 ataaaaagaa aaccttaaag gacgtgtcct tagattttta cccaaatgaa atcacagcac
     9841 tcattggccc ttcagggtct gggaaatcaa cacttttgcg ttccatcaat cgcatgaatg
     9901 acctgaatcc agaggtaacc attacggggt caatcgttta taatggacat aacatttaca
     9961 gtccaagaac agacactgtt gatttgcgaa aagaaattgg tatggtcttt cagcagccca
    10021 atccctttcc aatgtctatc tatgaaaacg ttgtctatgg cttgcgccta aagggcatta
    10081 gagataaggc tgttttagat cacgctgttg aatcctctct caaaggagcc tccatctgga
    10141 gtgaggtcaa ggataggctt catgattcag ctgttggact atcaggaggt caacagcagc
    10201 gtgtctgcat agcaagggtt ctggcaacca gccctaaaat cattttgtta gatgagccaa
    10261 catcggcttt agatcccatt tcagccggca aaatcgaaga gaccctgttc tcactaaaaa
    10321 aggattatac gatggttatc gttacccgct ccatgcagca ggcctcgcgc ttgtcagacc
    10381 ggacaggctt cttcttagag ggagaccttc ttgagtttgg tcctactaag gcaatgttta
    10441 tgaaccctaa gaggaaggaa acagaagatt atatttcggg taaatttggc taagggatct
    10501 tgtttgtagt ctaggtatcc gctctgttta ggataataaa tgaatcaata gaaagaaaaa
    10561 atgatgttaa gaactaaatt tgaagaagaa ttagacaagc tacacaatca gttttactct
    10621 atgggaacag aagtcttgtc tcaaatcaat aaaaccgttc gtgcctttgt cagtcatgac
    10681 cgcgaattgg ccaaagaggt gattgaggaa gacgatacca tcaatggatt tgaaacaaaa
    10741 ttagaaaaaa agtctcttga aattatcgcc ttacagcagc ctgtttcaaa cgatttgcga
    10801 acagttatta ctgttttgaa ggcctcaagt gatattgagc gtatgggaga tcacgctgcc
    10861 tctatcgcta aagcaaccat tcgcatgaaa ggagaagagc gtatcccgat tgttgaggag
    10921 catatcaact tgatggggaa ggcagtcaag cagatggttg aagaggcgct aaatgcttat
    10981 attaatgcag atgatgccaa ggcctatgaa attgctgctt cagacgaaat cattgataat
    11041 tatttccgcg aaatccaatc tctagctgtc gaagaaattc gcaagacacc agatgccgtc
    11101 tttgctggca aggaatactt ccaggttctc atgtatttag agcgtatcgg tgactatgct
    11161 cgtaatattt gtgaatggat tgtctattta aaaactggaa aaattattga attataagaa
    11221 agtatggtat aatgggggct gggtgaactt ctcagttcct cgttttatta tagcgattaa
    11281 aaggttttag aggctggagc ttcagctgag ctgactatca gctgtcaagc ttctagacaa
    11341 aatgaaagat aacaataagc tagtcgtcta agggactaga cggcaggatt gattatatta
    11401 agaatgtgac cttgtcccat cactaattta atgacatatt aaggagttgt atgaaaaaag
    11461 tagaacatct tattgaaaag tttattcctg aaaattataa tattttctta gacattaatc
    11521 gcagcacaaa aaccttcaca ggtaatgttg caatcaatgg tgaagcatta gataatcaag
    11581 tgtcatttca ccaaaaggac ttggcaatca atgccatttt acttgacaat gaagctgtta
    11641 gctatcatgt tgacgatgac aatgagcttg tgcgtgttga gctgccagag actggtatga
    11701 tgacgcttgt cattgaattt tcaggtaata ttactgacaa tatgactggt atttacccgt
    11761 cctattacac aaaagatggt gaaaaacagg aggttatttc aacgcagttt gaaagccatt
    11821 ttgcgcgtga ggcctttcca tgtattgacg agcctgaagc aaaggctacc tttgacttaa
    11881 gcttgacatt tgaccaagca gagggcgaga ttgctctatc aaatatgcct gaggtcaatg
    11941 ctgagcgccg caaggagacc ggtctttgga cctttgagac aactcctaga atgtcttctt
    12001 atctgctggc ctttgcctta ggagacttgc atggcaaaac aacaaaaagt aaaaacggga
    12061 caacagttgg tgtttatgca accaaggctc acccactgac ctcgctagat ttttcattgg
    12121 atattgctgt acgtgtcatt gatttttacg aagactactt tggggttcgc tatcctattc
    12181 cgcaatctct aaatattgct cttcctgatt tttcatctgg agcgatggaa aactggggct
    12241 tgattaccta tcgtgaaatt tacctgttgg ttgatggcaa ttcaacagcc cgcagcagac
    12301 aaaatgttgc tcttgttgtg gcacacgaga ttgcccatca atggtttggt aatcttgtaa
    12361 ccatgaaatg gtgggacgat ctttggctaa atgaaagctt tgccaatatg atggaatatg
    12421 tagccatcaa tgctattgag ccgtcatggc gtatttttga ggatttccaa acaacaggtg
    12481 tgccgctggc tcttaagcgt gatgcaacag acggtgttca atcagtccat gttgctgtta
    12541 atcacccaga tgagattaat accctgtttg atccagctat tgtctatgcc aaaggtagcc
    12601 gcttaatgca tatgcttcgt cgctggattg gcgataagga ttttgcggca ggtctgcgcc
    12661 tttactttga aaagcatcaa taccgtaata ctgtaggacg tgatttgtgg caggctcttt
    12721 cagaagcttc tggtaaagat gttgctgcgt ttatggacgc ttggctagag cagccaggct
    12781 atcctgtctt aacggccaga gttgacaatg atcagttgat tctcagccaa aagcagttct
    12841 ttattggtga ggcaagcgac caaaagagac tatggccaat tccactaaat gcgaactgga
    12901 aaggtcttcc tgacgtactg acagaggagt ccatcgttat ttcaggcttt agtcaattag
    12961 ccgcccaaaa taaaggaaca cttcgcttta atacagaaaa tacagcgcat tacattacag
    13021 attatcaggg acagctcttt catagcttag ttgatgattt gaagcatctt gacaacacct
    13081 ctgcccttca agtgattcaa gagcgccgct tgctggctga tagcggtctg atttcttatg
    13141 cagagctggt tgacttaatc gctcagctag atgacaaaaa atcctatatg gttgctgcag
    13201 ctgttcagca ggttattaga ggcttagagc agttcattga tgaaggaacc tcagcagagc
    13261 agtccttcaa tcgattgatt tcttctattt tccaagagga cttcaggcag cttggatttg
    13321 aaaagagggc aaatgaatct gatgaagatg aaatggttcg tcaaattgct ttacatcacc
    13381 tgttggttgg aggcaatcgt gatgtgatca agcaggccaa gactatcttt gaagcttatg
    13441 caaatcgtat cgaagccatt ccagcagcca ttcgccgctc ggtattggtg agtcagatca
    13501 agtattttga aatagctgac ttggttgatg cttattttga tgcttatgtt gcaaccaagg
    13561 acaacaatct tcgagctgat ttgagcgccg ccttagcaac aacagctaat ccatcaactc
    13621 ttaagcgcat tcagtacagc ttaaaggata aggatattat taagccacag gacttagcag
    13681 cttggtacag ctttttgctt gatcaggcct ctgcacaaga aagcatttgg cgttgggcta
    13741 gagaaaattg gaagtggatt aaggcttcac tgggtggtga tatgagcttt gacaagttta
    13801 ttatttaccc tgctaaccat tttaaaacag cagagcgttt agctgaatat aaggccttct
    13861 ttgagccaca gcttgatgat atggcgatta gtcgcaatat ttcgatgggg ataaatgaaa
    13921 tttcagctcg agttgccctc attgatagtg aaaaggaagc tatcgctaat gctttaagtc
    13981 agtactaatg atatcacaaa ggagctgggg accatcctca actcctttat tggtgtcaaa
    14041 gctactatct ttaagtaaca tttagatcaa agggtaattg ctgtagctta gtggcactgc
    14101 ctgtcagctt ttggcaaatg aggaggcttc aatcataagc agtggttaat cttagcgccg
    14161 taaattacta gttgatcaga gtcagagctt aggacggata ggtcatagag acaattcttt
    14221 gtctgtcagt tttataactt aagtaggtct ccagactaac tgtatgctta tgacctgtca
    14281 tgagcaatag tttagcaaag cttaagcttt ttgtgttatc gttagattag agaattcatt
    14341 tagtaaggta atccctaaag actacttgag cgaggctgtt agtctttaga gaattgaggt
    14401 atcataatga taaaactatt attagtagaa gacgatttaa gcttgtcaaa ttctatcttt
    14461 gattttttag atgactttgc tgatgtgacg caggtttttg atggtgacga aggactctat
    14521 gaggcagaaa gcggtattta tgatttgatt ctgttagatt tgatgctgcc tgaaaaggat
    14581 ggctttcaag tgttaaaagc cttacgtgaa aaagacatca aaattcccgt cttgatcatg
    14641 actgccaaag aaagcatcga tgacaaaggg catggctttg agcttggtgc tgatgactat
    14701 ttaaccaagc ccttttacct agaagaatta aaaatgcgga ttcaggcctt gcttaagcgc
    14761 gtaggaaagt ttaatgacaa gagccttaaa tttggcaacc tgactgtaga tactacccgt
    14821 aaagaggtac aggtcaatgg gcaggccata gagctattag gcaaggagct tgatttacta
    14881 atctatatcc ttcaaaatca aaatgttatt ttgccaaaat cacaaatttt tgatcgtatc
    14941 tggggctttg atagtgatac cactatctct gttgtagagg tctatgtctc taaaattcgt
    15001 aagaagctta aggggacaga ctttgttaat catcttcaaa ccttgagaag tgtaggatat
    15061 atcttaaaag ctaatgaata aactaaaaaa aggattattg tccgataatt atacgcattt
    15121 ttttcatttc tttgctattt ttacaggcat ttttgttgtc atgaccatca ttattttaca
    15181 aatcatgagg tttagtgtct attccacagt agacagcagt ctcatttcgg tcagtcaaaa
    15241 tgccagcaac tatgctaata ggaccatggc gagaatatct tccttttatt ttgatgcaga
    15301 aaataacctt attcaggctc ttcctgaact ggaagcgtca aaatcacttg gctcctccac
    15361 cactaatatg gatattattt tatttagtgc taatgggacg atattgaact cctttgacgc
    15421 tttctctaat taccaaagct ttcgtttaga caaaagccag ctcaataaca ttgtcaccac
    15481 acagctgatg aatttttatg ggcaaaagga gaaataccat accctaaccg ttaaggttca
    15541 cattaaaaac tatccagcag tggcttatat gatggcagtg gttaatgttc agcagctgga
    15601 tactgctaat gagcgctatg aacagattat tatcatggtt atgattgtct tttggttaat
    15661 ttcgattttg gccagtattt atttggctaa gtggagcaga aagccaatta tggagagcta
    15721 tgccaagcaa aaaatgtttg tagaaaatgc cagtcatgag cttaggactc ctttagcggt
    15781 gctgcaaaat cgtttggaat cgctgtttag aaagcctaac gaaaccattt tagacaatag
    15841 cgagcatatt gcgtcaagcc tagatgaggt tcgtaatatg agaatattaa caactaatct
    15901 gttaaattta gccagaagtg atgatgggat caagccgcag ctagttgatg ttgatgcagc
    15961 cttttttgat actgtttttg aaaattatca attagttgca gaagagtcag gcaagcagtt
    16021 tatctcagtt aatcagatca ataggccctt aaagacggat aaggctttgc tcaagcagct
    16081 gatgaccatt ttgtttgata atgcgatcaa atacactgat cataacggtg tggttgaggt
    16141 caaggttaga acgaccgata agcatttatt gatttctgtt attgataatg gcccagggat
    16201 caaggatgat gataagaaaa agatttttga tcgcttttac cgagtggata aggcaagggc
    16261 acgccaaaaa ggagggtttg gactcggatt ggccttagcg cagcagatcg ttacctcatt
    16321 aaaaggaacg attaccgtca gtgataataa gcctaccggc gccatctttg aagtaaaatt
    16381 atagcactga gttcttgcta gcccataatc agtatgaaaa taacagtcac tagatcaaga
    16441 agtctagtga ctttttttat tgtcttcttt ttgctgttga ccaagcagtt gacaagaaaa
    16501 ttccaataga tagtttaaag ccaataaaac cattattagg cttgcattac aggcaggtat
    16561 caaacaaaga tatagaaaaa tataccataa aaaatctcat aaaagtgtca aaatggtaaa
    16621 aaattgccaa caatatgtcg atattatacc attattatag tataatattt ataatcgtat
    16681 cataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ttgcaacacc
    16741 ttatgataaa gcataaagga atacaagcat gatagtctac ctaaagcaac acaaaaatta
    16801 ctggaaatta gtcagcatag ccgctttaat cattatttta ggaggaatac taacaatgaa
    16861 ttggcttaat ggcgaagagc taaaaaagaa aaagtacaga caagagcagg atagggtagt
    16921 gaaatacata ggagagcata tagagctatg taatggtcag cctataacaa aaattgagtt
    16981 tatagaattt cagttagaaa ctgcaaccac cggaacttgg tcaataacaa caattgttaa
    17041 tgagaaatat ctgattcatt tttcagaaga tagattaggt gaagaaatac ggacttccta
    17101 ttattctcca aaagaattta agcaatacag tgaaaagatg aggaataata tgactaatgt
    17161 tgaaacaatt tattacgagg agaaatgatg attgatagag attataaaaa tatttcagag
    17221 gatgtgtata aggttgattc tggtaaagaa agagatccga ttcaagaagg atatccggtt
    17281 gccaatggaa aataccgcgt tcttgaagcc gaagataacc ccgacaatgg tatgcaggct
    17341 atggctgttg tgccaataaa agatggcaaa gaggatagaa gtcatatcgt cattgcctat
    17401 gccgggacaa atagcagtga tatacgcgat attgacaccg atattcaatc cgttgttttt
    17461 ggagatgatc aatacctgtg tacccatgag gagcctgatt cttttaaagt ggtcaagagt
    17521 cagctaagta ctgctaaagc cttttccgac tacattagga caagctaccc taacgctgcc
    17581 atctcctaca ccggacactc tctgggaggc tatctggcac tcatcacagc tgcccatgcc
    17641 aagcagcctg ccactgtctt taatgcgcca agctctgtta ataacctctc caaggaggct
    17701 attgactttg ttaaagccaa caagggactc taccacagct accgcattaa caatgactac
    17761 attggaaatc tgggcactta ctttggagat gatgagctag ggatttcaag atgggttgac
    17821 ggtaaggcgg gaataggacg tcatagctta gccgcttatc gcttcaactc aaagggtcag
    17881 gtgattgacc gtaagggtcg tcctgccgct gctcaagcac ctgctcttgc taccctaagc
    17941 tcaaagctaa ccgaataccg cctgctaaag aaaaagtatg tagcctctaa cggtattagc
    18001 agctcagagg agttttacct tgatcagttt caggctcgag cagtcgcaca ggctttggag
    18061 cagaccactc agcttgccca agaggagatc attgctcgcc ggaaggaggc ggttgcagag
    18121 gcagaggcac ttcaccaaaa gacaagagac atgccctttt ttgtgagtga attgagctgg
    18181 gcggagctag aggaggctta tgcccaggca ggagtgacct atgacagcct tgtgggtcag
    18241 accaagaggc attttgatga caaggttact caagctagag gactggccac aaagttcaag
    18301 accgtaaagg agcagctaga ggagggggtt gagagaacag ctgctattga tcaaaagcta
    18361 ggatgcgact tttcatgaca gcattagaaa agatcagaac tgctatccgt caaaaggaag
    18421 aggagctaga ggagcagcag gagcactatc atcaagagcg gctccaaatg gcagcagccc
    18481 atgacgagtt aagaggcaac tataaccagc tacagcagct ctatgcctct agctatcagg
    18541 ccgttagcag ctacctcaga cattatgatg ctagtctgat aacagaccaa tataccgttc
    18601 taacgaggct gattgatgac taccagcacc gaacagagca gtgctatcat gagcaaggtc
    18661 gcaagatgtc gcagcaggag gaagcaattg accatcacta tcgcagccag cgacaggcga
    18721 tagaaaagga catcacagcg ctgaggcgtc agtggcgtga aggttaagga aaaggagata
    18781 agaaagatga ttgctataga gatgatctta accggacaag agccgatcag gactttaaag
    18841 aaagagctgg ataggagatt agttcagtcc atatgtgctc ccttgacctt aggtcgcctt
    18901 catgcccttc aaaggcgcta tgacagtgag gtatctcgga ttgccacaga caccgcagat
    18961 catattcaga ccattgtcaa tcagctagat agcagcatta gagggca
//
LOCUS       DARYJX010000042        18394 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYJX010000042 DARYJX010000000
VERSION     DARYJX010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18394
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            174..554
                     /locus_tag="TU257_001617"
     CDS             174..554
                     /locus_tag="TU257_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL0834617.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            554..1402
                     /locus_tag="TU257_001618"
     CDS             554..1402
                     /locus_tag="TU257_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0834618.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1502..2713
                     /locus_tag="TU257_001619"
     CDS             1502..2713
                     /locus_tag="TU257_001619"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL0834619.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2706..4573
                     /locus_tag="TU257_001620"
                     /pseudo
     CDS             2706..4573
                     /locus_tag="TU257_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4678..6423
                     /locus_tag="TU257_001621"
     CDS             4678..6423
                     /locus_tag="TU257_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834620.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6423..8199
                     /locus_tag="TU257_001622"
                     /pseudo
     CDS             6423..8199
                     /locus_tag="TU257_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8340..9689
                     /gene="gdhA"
                     /locus_tag="TU257_001623"
     CDS             8340..9689
                     /gene="gdhA"
                     /locus_tag="TU257_001623"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL0834621.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9821..10231
                     /locus_tag="TU257_001624"
     CDS             9821..10231
                     /locus_tag="TU257_001624"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0834622.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10422..12428)
                     /locus_tag="TU257_001625"
     CDS             complement(10422..12428)
                     /locus_tag="TU257_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL0834623.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12877..14598
                     /locus_tag="TU257_001626"
     CDS             12877..14598
                     /locus_tag="TU257_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834624.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14600..15763
                     /locus_tag="TU257_001627"
                     /pseudo
     CDS             14600..15763
                     /locus_tag="TU257_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15915..16691
                     /locus_tag="TU257_001628"
     CDS             15915..16691
                     /locus_tag="TU257_001628"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0834625.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            16684..17649
                     /locus_tag="TU257_001629"
     CDS             16684..17649
                     /locus_tag="TU257_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL0834626.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            17745..>18394
                     /locus_tag="TU257_001630"
     CDS             17745..>18394
                     /locus_tag="TU257_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL0834627.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEA"
BASE COUNT         5471 a         3257 c         4300 g         5366 t
ORIGIN      
        1 cttggggtgt ttttttgttg taggagattg attggttgat agaaggcagg tttatattta
       61 ttgaagtgac aaggtctgga aaaaaattat ccaaaatact ggtttaagtc tactttaata
      121 ttcgtcaaat ctatgctata atgggtcata tcgccattaa ggagaacgaa atcatgcaat
      181 tagtacgtga aaaagaattt gtcaatcagt accattatga cgccagaaat ttagaatggg
      241 aaaaagaaaa tggaacaccg gaaacaaact ttgaagtaac ctttcagttg attaataaag
      301 atgtggaaaa taaagagacg gctattgttt ctgttttaca atttgtcatt gtcaaggaag
      361 agtttgtgat tagtggtgtg atttcacaga tggttcgtat tttaggacgc ttggtggata
      421 agcctagtga atttacacaa gaggaggtcg aatccttggc tgctccatta ttagacatgg
      481 tgaagcgctt gacctacgaa gtgacagaaa ttgccttgga tcgtcctggt attaatttgg
      541 agtttaaaag ttaatgaagt tagcaataat aactgataat acagctcacc ttccagagca
      601 gttagcggag catgccgata tttttgtatt agacatacct gtaatcatag atggtcaaag
      661 ctatgtcgaa ggacaaaacc tgaccattga agccttttac caaagcatga gagaatctca
      721 agagctgcca aaaaccagtc agcccagcct ctctgaatta gatgatttac tagggcgtct
      781 gtcaactgag cactatactc atgtgattgg cttgttcttg gctagtggta tttcaggatt
      841 ttggcaaaat attcaatttc tcatcgagga gcaccctgag ttgaccattg cttttccaga
      901 tagtaaaatc acctcagcac cattaggcag catggttaga aatgctttag agtggtctca
      961 gcaaggcttg agctttgcag agattatgga taagctagaa gagcaaatcg ctggaaccac
     1021 agcctttatc atggttgatg atttgaatca tttggtcaag ggaggacgct tatcaaacgg
     1081 ttctgctttg ctgggaaatt tgctcagcat caagccaatt cttcgctttg atagtgaagg
     1141 aaagattgtc gtctatgaaa aggttagaac ggaaaaaaag gccatgaagc gcttggttga
     1201 tatcttaaag gaattgacag ctagtggtca gtacgaggta tcaattatcc atgctagagc
     1261 gcaggataag gctgatatct taaagcagct cttgttggat aatggctata cctgccctgt
     1321 tgaggaggtt cattttggtg cagtgattgc agcccatctt ggagaaggag ctgttgcctt
     1381 tggcataacg cctcttgtct aaagaggctt gcccatgacc aatctgagct tgatatgaca
     1441 gcctttaacg ggaagcatat gacaaggctc taggagcttt taggtggtag attaaaacat
     1501 gataacatta atgacaatgc cttctgaatt tcagaaggct ttaccaatag tgaaaaaaat
     1561 caagcaggct ggctttgagg cctattttgt tggtggaagt gtgagggata gcttattaaa
     1621 caggcctatt catgatgttg atatagctgc tagctgctat ccagaggaga caaaggctat
     1681 tttcttaaga acaattgatg ttgggattga gcatggcaca gtgcttgttt tagaaaatgg
     1741 cagtgaatat gagatcacaa cgtttcgaac tgaggacgtt tatgtggatt ataggcgccc
     1801 tagtcaggta tcctttgttc ggtccttgga agaggattta aaacgaaggg attttactgt
     1861 caatgctctt gccttagatg aggacggaca ggttattgat atctttaatg gcttagagga
     1921 cctaaagcat aagcttctaa gagctgttgg aaggcctcag gagcgctttg aggaggatgc
     1981 cctgcggatt atgcgaggct ttcggtttgc tgccagctta gattttgata ttgaggctga
     2041 gacctttgaa gcaatgaaaa gccatgctcc cttgctggag aagatttcta ttgagcgctc
     2101 ttttattgag cttgataagc ttttaatggc cccaaaatgg cgtaaaggta tcttagctat
     2161 ggtggcatgt caggccttta actatttgcc aggcttagtg ggcaaggaag aagccctgca
     2221 aaagtacctg aaaaccttag cagcggatta tgtgtttcag gacaatcatc aggcttgggc
     2281 ctatttgctg gttatgctgg agcttgatca gcctaaagcc tttttaaagg cttggaaaac
     2341 ctctaatgat tttcagcgta gggttacgat gatggcctct ctttatcaga ttcgccaaga
     2401 aagacagcta gaaaaatggg atatttactc gtttggcaag gacttggctt tactcgttga
     2461 cgatttacga caggcacagg gcttggtcag tgaggccaag cgtgttgaga gcttgtatca
     2521 ggagctgacg atccatgata agcatgatat tgtggtcaat ggctcttatc tgattcgtga
     2581 gcttggaatg aagccaggac cacagctggg aatgctttta aatcagattg agcaggccat
     2641 tgtagagggg cgtctcgtca atcaaagaga acacattgag gcttttgtta gaagggaact
     2701 actaaatgag tgattttatc gttgaacatc tgacgaagtc tgttggagat aagaccgttt
     2761 ttcaggatat ttcctttatt attcatgctg gtgatcgcat tggcattatt ggtgtcaatg
     2821 ggacaggaaa aacaaccttg cttgatgtta tttctgaaaa agtgggcttt gatggtgacc
     2881 gctcaccttt ttcaaaggca aatgactatc gtatatctta tttaacacag gagccggact
     2941 ttgatgatga tcagtctgtt ttagatactg ttctgtccct agaattaaag gaaatgcagc
     3001 tgattcgcca atatgagctg ttgatggctg actattcaga tagcaatcag gaaaagctag
     3061 cagaggtgat gactgagatg gatcgattag atgtttggtc gatcgaaagt gaggttaaga
     3121 cggtcttatc aaagcttggt attgtcaatc tggatcagag agtgggtgac ctgtccggtg
     3181 gtatgagacg tcgggtacag ctggctcagg tcttgcttgg agccagtgat ttgttgctgc
     3241 tagatgagcc gaccaatcat ttggatattg ataccatcgc ttggttaagt cattacttaa
     3301 ggacctctaa aaggactgtt ctatttatta cacatgatcg ctattttttg gatagtatag
     3361 ccacacgtat ctttgaattg gataaggctc atgtgactga atatcagggc aattaccagg
     3421 attatgtgcg tctgaaggct gagcaagacg agcgcgaagc agctcatttg cataagaaaa
     3481 agcagctcta taaacaggag ctggcttgga tgaggacaca gccacaggcg cgtgcgacca
     3541 agcagcaggc cagaattaac cgctttgaac agttaaaaaa ggaccttcat caggaaaggc
     3601 ctatagatca attagatatg gcctttgaag ccagtcgtat tggcaagaag gtcattaatt
     3661 tcaaggaggt ttcctttgct tatggtgatc aggccattat tgagcatttt aacctgatca
     3721 ttcaaaataa ggaccgtatc ggcattgttg gagctaacgg tgctggaaag accaccctgc
     3781 ttagcttgat gactggtgac ttaaaaccaa cagctggtca gctagagatt ggcgagacga
     3841 tccgtattgg ttatttttca cagcaaatca aggatatgga cggcagcaag cgcgtgatta
     3901 gctatttgca ggaggtggca gatgaggtca agaccagtgt tggcaccact agcatcagtg
     3961 agcttttgga gcaatttctt tttccgcgtt ctagtcatgg ctccttaatc gctaagctat
     4021 caggcgggga gaaaaaagac tgtatttgct aaagctcttg atcgaaaagc ccaacgtcct
     4081 gctgctggat gagccgacca atgatttgga tattgcaacc ttgacagtgt tggagcattt
     4141 tttagctcaa tttgctggtc cggtcattac agtgagtcat gatcggtatt tcttggataa
     4201 ggttgcaaca aaagtattgg cttttgagca tggagctatc agagaatact atggtaacta
     4261 tagcgactat ttagatgaaa aggcttttga agcagaggtc atagagcctg ctgtcagtga
     4321 gcaaaaagct ggcactgacc atcaggtcac ctctaaaaag agaatgtcct atcttgagaa
     4381 aaaggaatgg gcagctattg aagaaaagct agctgctatc gagcaacaaa tagctactat
     4441 tgaggagcaa atgctcagag cggcaagtga ttacgaccaa ttggcacaat atcaaaagga
     4501 gctggatcag cggaatcttg agctgcttga agcctatgag cgctttgatt acctaagcga
     4561 attagaagaa taattaatta tgtgtcaatt tcatattttt gtgttaaact agttatagac
     4621 aaaaagaagt gctagcttgc gcttcttttc atatcactat tatttgggag gaaatgaatg
     4681 gctttaattt ggtcctattt aaaaacaaga cctaaatgga tttgtttcga tattgtgggt
     4741 ggcttgttat ttgttctggt caatctgggg ctaccaacaa tattggctcg tatgattgat
     4801 caaggcgtta tgcagcagga tcaaagggct ctttattttt gggctctgat gatgtttatt
     4861 atcgtacttt taggtgtcat tggacgggtg attttatcct atgcttcggg taagctaacc
     4921 accaacatga tcaaggattt acgtaatgac atgtatagct gcttgcagga ttattcgcat
     4981 tcggaatatg aaaaaattgg catagcctcc ctggttactc ggataacaaa tgatgccttt
     5041 gttttgatgc aatttgctga aatgtccttg aggctgggtg tcgtaactcc tttgatgatg
     5101 atcttttcag tggtgatgat ctttttaacc agtccatcat tggcttggat tgtggctgtt
     5161 gccatgcctt ttttagttat tgtggtgctt tatgttgcga taaagacaag acccttatca
     5221 gaaaagcagc aggagagcct tgatcgtatt aaccaattgg tgcgtgaaaa cctgacaggt
     5281 ctgagagtta ttcgagcctt tgcaagagaa gactttcaag aagagcgctt caataagcgc
     5341 aatgatcact attctggaat ctcaaagcga ctatttacct tgacaggctt aacagagccc
     5401 ttatttgtgc aaattatcat tgctatgatt gtggggatcg tctggtttgc cttggatccc
     5461 ttggcaaggg ggcagtttaa gattggtgat ttggtggcct ttatcgaata tagctttcat
     5521 gctctttttt catttttaat gtttgccaac ctctttacca tgtaccctaa aacagcagtg
     5581 tcaagcaagc gtatcaagga agtgctggat atgccgattt cgattcctaa aaatgaagat
     5641 ggtataacag cgttcacaac acgtggttat ctagaatttg ataacgtgac ctttgcctat
     5701 ccgggtgaaa cggaaagtcc agttttacat aacatctcat ttaagactag gcctggagag
     5761 accattgctt ttatcggctc gacaggttca ggaaaatcat ctttggttaa tctgatccca
     5821 cgattttatg acgtgacctt agggagaatc ttggttgatg gcattgatgt cagggattat
     5881 caattaaaag cgctgcgttc taaaatcggc tttattcctc aaaaagccct gctatttaca
     5941 ggaaccattg aggaaaacct aaaatatggt aagtcagatg ccagccacag tgagcttgag
     6001 caggcaacag aggtttccca agcgaaggac tttattacca gtcgtgaaaa gggctatcaa
     6061 acccatctag ctgaggccgg cagtaatcta tcaggagggc aaaagcagcg cctgtctatt
     6121 gccagagcag tggtcaagca gccagacatc tatatctttg acgattcctt ttctgcccta
     6181 gattacaaga cagatgctga attacgcaga cggctgaaag aggtgacaca agatgcaacg
     6241 gtcttaattg tggctcaaag ggtgggcacg attatggatg ctgatcaaat cattgtcttg
     6301 gatcagggag aaattgttgg ccgaggtaca catgaggaat tgcttacaag caatgccatc
     6361 tatcgtgaaa ttgccaattc tcagctaaac aaggaagaca tgacaaaaga ggagggggat
     6421 taatgactga aaagcatgtg tttagaagaa tttggaccta ccttagtgcc tataggctct
     6481 cactaataac tgccattatt ttaaaaatag tcagtgctgt gatgagtgtc ttagagccct
     6541 ttgttcttgg cttggtgata acagagctat ctgcaaacct attagacata gcaaagggag
     6601 tctctggtgc aggcattaat aaaacctata tcgcctttct tttagctctc tatatcatta
     6661 gggcccttgt ttacgagtta ggctcttatg gttcaaacta ttttatgaca agggctgtgc
     6721 aatcaagcat ttgtgatctt cgtcgagacc tcagtcaaaa aattaatcgt atccctgtgt
     6781 cttattttga taagcatcag ttcggcgata tgctaggccg gtttacctct gatgttgaga
     6841 cagtctctaa tgccttacag cagtcctttt tacagattgt taacgccttt tttaccctta
     6901 ttttggtggt tggcatggtc ttgtatatta atgcccccct agcctctgtt gtgattatcg
     6961 ctatcccgtt gatatatgct gcttctcgat ttgttttaaa aaaatcacag ccttatttta
     7021 aagcgcaggc taatattttg ggagaaatga atggctttgt gcaggaaaat ttgaccggct
     7081 ttaatatttt aaaactgtat ggtcgtgaag aagcctcaaa ggaggaattt caccagatca
     7141 ctgagcgatt acaagaagta ggctttaagg ccagctttat ttctgggatc atgatgccag
     7201 ttctgcattt tatttcagat tctgtttaca tgattgttgc cttaatcgct ggcttacagg
     7261 tgatagcagg ccgcctgaca atcgggaaca aacatgcaag cctttgttca gtacatttgg
     7321 caaatcagtc agcctattca gaccataaca cagctggctg gtccactgca aagtgccaag
     7381 tcatccttag aacgtatctt tgcagtgctt gatgaggcag atgaattgac tattgcccaa
     7441 gagcatttag aacatgattt aacaggtcag gtgtccttta atcaggttga ttttagctat
     7501 acagcagaca atcctctgat tagaaatttc aatttagagg ttaagcctgg tgagatggta
     7561 gctatcgttg gtccgacagg agccggcaag accaccctga ttaatttatt aatgcggttt
     7621 tatgatgtga atgagggctc tatcacagtt gatggtcagg acattcgtca gttgtcacgt
     7681 caagcctata ggcgtcagtt tggtatggtg ctgcaggacg cttggctctt tgagggcagc
     7741 attcaggaaa acttgcgctt tggtcattta gaggcgactg atgaacaaat aattgaggct
     7801 gctaaggctg ccaatgttga tcatttcatt aggacattgc caggtggcta tcatatggtg
     7861 atgaatcagg aatctagcaa tatttccctg gggcaaaagc agctgctgac cattgctcga
     7921 gctctcttag cagatccaaa gctgctaatc ctagatgagg ccacctcgtc tgttgataca
     7981 cgtttagagc ttttgattca aaaggcgatg aagcgattaa tggttggcag gactagcttt
     8041 gttattgctc accgcttatc aaccattcaa gaggcggata agattttagt tctaaaagat
     8101 ggtcagatta tcgagcaggg gaatcatgac agcctattag ctgctaaggg cttctattat
     8161 gagctttatc atagccaatt taagaccagt cagtcttaaa aagcttaggg tcttggaatg
     8221 aatcgttcca aggctctttt aatttgcttt agatcatagt aaaagcttga catcaaaatt
     8281 cagaaaattt ataatattga ctatacttaa aatagaatga agaagcgaga ggatatataa
     8341 tggtatcagc aaaagactat gtagccagtg tttttgataa ggtcaaaagg gataatccgc
     8401 atgagactga atttcttcag gcggtcaagg aggtatttga ttccttgatt cctgtttttg
     8461 aaaaataccc taattatatt gaggaaaatc tattagagcg cttggttgag cctgagcgtg
     8521 tgatttcctt tagggtgcct tgggttgatg accagggcag ggtccaagtt aatcgtggct
     8581 accgcgtgca attttcatca gctatcggtc catataaggg agggcttcgc tttcaccctt
     8641 ctgttaacca gtctatagtt aaatttcttg gctttgagca gattttcaaa aatgctctga
     8701 ctggtcagcc tattggagga ggaaaaggag gatcaaattt tgatcctaaa ggcaaatcag
     8761 acctagaaat catgcgcttc acacaaagct ttatgacaga gctgcaaagg catattggac
     8821 ctgaccttga tgttcctgct ggtgatattg gtgtaggggc tcgcgaaatt ggctatttat
     8881 ttgggcaata taagcgtctt aatggcttta agaatggtgt gttgacagga aaaggcttag
     8941 cttatggtgg ctctttggct cgcacagagg ccacaggcta tggtgtggtt tattttgctc
     9001 agcaaatgct ggcggctaag gggcaggact tggctggtaa aacagctatt gtatctggat
     9061 caggaaatgt tgccatttac gcaacggaaa aattgcaggc cttaggtgtt aaggtattag
     9121 cagtgtcgga ttcctctggt tacgtttatg atgataaggg cattgatctt gagaccctaa
     9181 agcaaatcaa ggaagtgaag cgtgagcgta tcaagaccta tctagagagt cacccggctg
     9241 ctgtgtttac accggctggt gagggatcca tctggactat taaggcagac cttgcctttc
     9301 catgtgcgac tcaaaatgag ctacaagagg cagatgctaa agccttgatt gagcatgggg
     9361 ttaaagctgt tgtcgaaggg gctaacatgc cctcaacctt agaggctatt gagcaatttc
     9421 agcaggctgg ggttcttttt ggacctgcta aagcagcaaa tgctggcggt gtagcagttt
     9481 ctgcgctgga aatggcacaa aatagcggac gtaccgcatg gacctttgaa gaggtggatc
     9541 atcgattgta tgacatcatg aaggctattt atcaaaaagc agccgctgcc gccaaggaat
     9601 gtggtcaaga aggcaaccta gtggtgggag ctaatattgc aggctttctc aaagttgctc
     9661 aggccatgtc agcacaggga atcgtttaag agctgtggct ggtatatgct gaatatatca
     9721 gtagggttag cacattaatc ttagctcaat gacgttaaga tatacgatcg gtcatctaga
     9781 caatgcatgc cgattagagc aatgaatcaa ggagaagctg atgatcaaaa aaatcgtgaa
     9841 ggacaccttt ttcttgcagc aaaaagcaca gccagcaacg aaaaaggacc tttggattgg
     9901 tcaagacctg caggatacct tagcttatta tcgtgatagc tgcctggggc tggctgctaa
     9961 tatgataggg gaaaacaaga gggttattat tattagcatg ggctttgtgg atttggtgat
    10021 gtttaatcct gtattaattg ctaagcgtga agcgtttgag gcagaggaat cctgcctatc
    10081 actaatcggc caacgtaaga caaagcgtta tcaggagatc aaggttgatt accttgatgc
    10141 acattggcac aagaaatccc tgagattgac aggcctgcct gcacaaatct gccagcatga
    10201 gctggatcat ctggagggca tattgattta aatcatgacc acccgttagt gaactgcacc
    10261 ccaaaagtta gacagaaaat ctaacgaatg agggcagtcc atagatgggt ggtttatttg
    10321 tcttgctcaa caggtgcgaa acaaataaac gtcacataaa tcagaaaacc ggctgtatgc
    10381 ttaagataca gtcggttatt gctgttatgg ctaggacgat tttattggcc ttcctttttc
    10441 ttgaaaaggc tagtaccagt taaggttagt agtcctagga ttgtcatggc agcagcagaa
    10501 tgctggcttg ttcctgttgc tggtaaggca gcattagctt gctttttagc tgctagaggc
    10561 ttgatgcttg tggcaggatt agcattttga gcaggcgtaa ataggtcaga gacaagctca
    10621 gtagcaagca ccttgccctc acgattctta aagacgcggt tgatgatctc gtgcttgccg
    10681 gtatgatcac tttgagtaga gccttcaaga ctggcagtga cataggtttt cacaccgtta
    10741 ataccagcac ttacagtctt tccagctgct tcaaggtcct tgatgtattc gataaagacc
    10801 tcagtatcag gattaatggc tcctagtagc ttagcgtcct taaagacgga gaagccatca
    10861 ccaccgccat ataggaagtc gttgatgatt agggtgtatt gagctgctgg atcaatttct
    10921 tcaccattat ctttataagc ctttactacc ttaaacggtg ttgaaggatc gttagcctca
    10981 ttagctgtat aagtgtattt gagtccagac atttgaagga agtatttttg gtcttcatcg
    11041 tattgttggt tcaagacatc atagatttgt tggccagtca tttgaacgac ctgaagaata
    11101 ttgccaaatg gttgaacagc ctgtgcagct ccccaggtaa tggtttgatc ctctttgacc
    11161 accaagtcag cgcgaatacc gccattattt gtcatggcaa aatcaacatg agggaaggtt
    11221 tttctaccaa tggttaattg ggcagttgtt atcaaattgc caacaggaga ttccttgtct
    11281 tcgttttctg ttttagaaat cgttgaagag gtagctgctg taccgatctt tagctcggta
    11341 acggttttga caatgtcatt ggcttgatca acaatggctt gaatgtcggc attgcctgtt
    11401 tttatgccag gagcaacggc aatgaccttt gcttcaggag tggctacaaa atcattgagg
    11461 tcagtgtcta gtgttccacg aacatctgca taggctttcc cctgtgaaac agcctgaacg
    11521 acacgtgttg tgccaatggt accgttggtg tattggtggt tgtgaccagc aaagacaata
    11581 tccacactat gctcaggata aagctggtta accttttcca taactgctgc catctcatca
    11641 tgaactaccc cgttatcact tgttgctggg atatgagcta ggacaacaat cgcattgacc
    11701 tgctgctctt ggagctcttt agcatattta acgatggttt ctgcagagtc taggtaatca
    11761 tattgttcat aattttgttt taggacaagg tttggaattt ctgttgtcac aacaccgata
    11821 aagcccacct tgactgactt atcattaact gggacttctt tgacagcata aggcttccag
    11881 ccaaaaggaa tcgtgttggt ctccttgtca acgacatttg caatgacaag ggtttgattt
    11941 gaagcttcat gctcgtattg cttagtaatg tcgttgatag ctgagtcttc agcaggtgca
    12001 gtgcctgtca tgatacggtt gaattcagct aagccctcat cgaattcgtg attcccaagg
    12061 gttccgtatt caaagcccat ctggttgaat accttaaccg ttggctcgtc ctgtaatagt
    12121 ccagaattag caggactagc tccgaccata tctcctggtt gaacacgaat gcttgtccca
    12181 tctgggcttg tttgcttaaa gtcagcctct gcatcgtcca gataagcagc taattgtgct
    12241 gcggtaccag cgttagatac ctttccttct ggcatgtagg cagagccggt tgtgtctaag
    12301 gcaccatgaa agtcattgac accaagaaat tgcacgtcta cctgatcggc ctgcacgccg
    12361 gttactagca tagaaactcc ggcaaagaca ccaagaacac tactttttaa aacaaaatgc
    12421 tttttcataa acgctcctaa aagtttaaag tattgtcaca agttaagtgt actattattt
    12481 aaatgagaat tcaacaaaaa ttaataaaaa agctaacaaa aattcaacga tagcgtttgc
    12541 taatcactga aaacgtttaa aatgcaaaca ttggaagcgt tttttgtaaa aaaatagaag
    12601 aactatccaa aaaaggcttt acaagcccag tattctatga taagatgtta ggcagattaa
    12661 aagaaaggag aaattaataa tgatccgttt cattcaacta tttaaccatt attacgatag
    12721 tctcctttct aaccaaaaca gttagtttct tttagtttca ctaaatagaa atagtagagc
    12781 ccgcggtagg aaggatatct tattgcgggc tttttgtgtg caaaaatcct attttaagac
    12841 agcttgaaat aggttagttc agaaatggag gatatgatgc tgaccttaat tgttcaacat
    12901 attaagcaaa agaaatggat ttatatcctt attgcaatga ctttagtgat atatgatgcc
    12961 tcacttgtga taccaacaag ggttattcaa gacttggttg atttgatgtc aaggcatcag
    13021 ctaagctcag gggcattggt gaggcatgtt atcattcttt tggctacggc agtagtgtct
    13081 tatggggttg cttatttgtg gcatcttcat ttatttcagg aggcagttca ttttaagttt
    13141 gatattcagc agcgtgcctt tcgaaagctt gtttttatga gaacgccttt ttatgagaaa
    13201 tttcgctcag gtgacatgat cacgcgtttt tcaacagatg tcgaagcact tatggacctt
    13261 atcggctatg gcttgatgat tatcctatat gctggtggta tgattgcttt tattattccg
    13321 accatgtttt tgatttcttg gaaaatgacc ttgataggaa tagtaccgat tttgcttatg
    13381 atggtgatga tctatggtgt gacgaaaaag caagagcatt tggttgaaga ggcgcgtgag
    13441 gcgatttcaa gccttagtga tgaggtacta gaaaccgttg agggcattag agtgatgcgt
    13501 gcttacagta aaaaagatta tttggcactt cattttgctc aaaagactca gaatttggca
    13561 gataaatgga atcaggtggc caagtatcgt gccttgtact ttcctcttta cagcgtcatg
    13621 attgccatta gtacagtaat cattttaatg gtaggcctac agctcatagc aagctcagag
    13681 gtaacacttg gtcaagtcat tgcgctgcag ctttatctgg tgtctttggt ggagcccttt
    13741 ggcatgctgt cagactttat tttggtttat cagacaggaa agacctcttt tggtaagatt
    13801 aatgaactca tcgaaacaag tgatgatatg gagcctgatg gccagcttga gttagagagc
    13861 tttgatcaga ttgcttttat agactatagc tttacctatg ccaatagttc taggcctagc
    13921 ttagaaaaga tcaatttaac cctgaaaaag ggacaaacct tagggattgt tggtaaaaca
    13981 ggctctggta aaacaaccct tgtcaggcag tttttgagac aataccctct tgggcagggg
    14041 cagctgatga ttaatcatcg tagtgtcttg gattataagc gtcaatcact tgagcgtcaa
    14101 attggctatg tgccacagga gcatatcctg ttttcaaaaa cggttgctca aaacattgcg
    14161 atggggaaaa aggcagctac aactgaggaa atcttggagg cgattgaaac tgcggccttt
    14221 acgcgtgatg ttcaaggaat ggcaaagggc ttggatactg agattggaga gcgtggtctg
    14281 tctatttcag gaggtcaaaa gcagcgtatt tcgattgcca gagccttttt gtcccagcca
    14341 gatttgctga ttttagatga ttccctgtcg gcagttgatg ctagaacaga gactgatatt
    14401 attcgacaca ttcaagacga aagaaaggga aagacaacac ttattgttag ccatcgcttg
    14461 tctgcgattc agcatgccga ttgggttatt gttctggatc aggggcagat agtagaggaa
    14521 ggtcagcccc aacaactttt agctcagaag ggctggtatt atgaacagta ccagcgtcag
    14581 caggctcagg aggtttaaga tgaccctatt tataaaatta ataaaagaaa ttaaagctgt
    14641 gaccttggct ttttccctgg caataggctt tttgctagtg gcaacagctg gaggtcagat
    14701 ggctccctta ttgttgcaac aaacgattga tcattacttg actccgatag ctagaggaaa
    14761 agaggtaccg attgaaggct ttcagcgctt gctcctgctg tatttgctgt taattgtgat
    14821 aacagcagtt ttgcgttata tctcttatcg aatgctggtt tattcctcta ataggatcgt
    14881 tgctaatctt cgtaatcgag cctttgatgt catgcagagg ctgccgatag cttattttga
    14941 tcatcagcct gcaggaaaga ttgcaactag gattgttaat gatactgaaa ccctgaagaa
    15001 tcaattttat gataaccttt tgtctcaaat tattgtcagt ctttcacaaa ttatttttat
    15061 ttatgtggtg atgatttacc ttgatgtgaa gtcaggcttg ctgttgctgc ttattatgcc
    15121 actcttttat ggcatgcaat ggctgtataa aagcttgact gaccagccaa tgaaggattt
    15181 ttatcaggct aggagcgctg tcaacacaca agtcaacgaa accatgaatg gtgtttctat
    15241 tattcagctt tatcatcaag aggatacgat cttagaggaa tttgaagagc agatccacca
    15301 gatgaaaaca gctgatgata ggattatttt tgcagagtca gttgcttcat ggaccctgac
    15361 ggaattggta aagtatggca tgattgccgc tattttggct gttattggtt accagttctt
    15421 gcaggggaga tcaggcatca cagttggtaa gctctttatt tacgtcaatt atttgctgcg
    15481 cttgtttgat ttattaagta tgctggttag gcagctacct aatattcagc gctcaacagc
    15541 gacaggaacg cgcctaatga agctgcttga ggcgcagaca gagccggata aagcacgagc
    15601 aattgagcta acagatggta ctgtggattt taccaaggtg tattttgctt acgaaaatgg
    15661 caagacagtt ttatctgata ttaccattca tgctgataaa ggggagacgg ttgccctagt
    15721 agggcatact ggctctgggg acaatgctat aatgatgata gtacaataaa tccaagtaaa
    15781 atcaatggtt aaaggcttcc gcaaaacttt taaacttgat gatggattga ggctatcatc
    15841 tttttttata tctaaaatta tataaaagta tagcataaaa tgaaatctct gtatagagaa
    15901 gaaggaggga ctttatggca gaagtgataa ccatagccaa tcgaaaaggc ggagttggaa
    15961 aaacaactac aactctaaac cttgcctatt cactaaaaga actggggaaa aaagtattag
    16021 tcattgacct tgatccacaa gctaatctta caagatgttt tgatatggga aatacagaaa
    16081 atataaaaac catagggcat ttgttaatgg tagaactgga ggaagaagaa agctatttgg
    16141 tagagggcta taccaaatct tatgatgaga tagatattat cccctcaagc attttcttat
    16201 ccgccgttga aacacaaatg agagcagaaa caggaagtga acgtatatta tcggaaatta
    16261 ttaggagggt aaaagagaat tatgactata ttctcataga tacatcacca tcacttagtg
    16321 ttttgactat aaatgctctt tgtgcctcag acagtgtcct tatagtagcg gatacacagc
    16381 tgttcgcagt tgttggaatc aatgaacttt taaaaactgt tcaaaaaata aaaaagagag
    16441 tgaatccgaa actgaaagtg caggggattt tactaaccat gtgtgagaat agaaccaatc
    16501 tgtccaaaac actgatggag caagtagaag aaatgttcca aaagaaaatc aaggtctttc
    16561 aaaccaaaat tccgaaaaca gttaaagttg gggaagccat ctatagcggg caaagcataa
    16621 aaaaatatgc aaaaggcagt agtgtagaca ttgcctatga caatctggca aaggagatct
    16681 gctatgagta aaaaacttct aaagagagaa atcaccgatg ccgtagattt tttgcttgat
    16741 gatggaaatg ccttggaaca aggaaatata cagaatatag aacttgattt gcttgaaaat
    16801 tatcataatc atccgtttac tttatataca ggtaagagat tagacgatat ggtagagagc
    16861 attaaggaaa acggagttct taatccaatt atcgtcttga aaaaagataa caactatgaa
    16921 atactttccg gacacaatag agtaaatgca gcaagaatta caaaaataaa aagtattcct
    16981 tgtattgtta aagaaaatct aacggataaa gaagcctata cctatgtaat tgaaacaaac
    17041 cttatacagc gttctttctc cgatttactg ccgacggaaa aagcccttgt tcttaaaatg
    17101 agatatgaaa aaatagcaag tcagggcaag agaaatgatt tgcaaaagga gataaacaat
    17161 ttagatcagg gaattataga aaaggaaagt aaagaggaag ataaaataga cagcagaaaa
    17221 acacttggaa aagaatataa tctttcaggg gcatctattg caaggtacct aagattaaat
    17281 gaattatcta agtcttggaa aaaagatgtg gatgaagata aaataggttt gacgatggca
    17341 gtagatttat cctatctttc caaagaaata caggaatatc tgtatcagaa gtgcgaagaa
    17401 ttggaactaa gtttaaaacc aagcgatgcc aaagcactcc atctgatgaa cagacaagaa
    17461 gatctgaatc aagagatggt tataacatac ttgctgaact tgaaaaaaac gaaggtaaaa
    17521 aagtatcaga atatcaaact atctcagagt gtctataaaa agttttttca tgatgaaagg
    17581 aaagaagatg tagaagaaat tatagaaaaa gcattggaaa tttactttaa ggaatatatt
    17641 ggtcagtgaa aagacaaaat tataaattta aggtataata taaggtatta aaaagggaaa
    17701 agacctgttt aacaggataa gatataaaag aggcaggtgt cagaatggac gaaataaaat
    17761 tgtatgaaaa taaagagata cgctccattt gggacgaaga aaaagaagag tggtattttt
    17821 cagtagtcga tgtagttgga gttttgacag aacaagaaaa cgtaagaggt gctagtacct
    17881 attgggctgt actaaaaaag agattaaaag aagaaggaaa tgaactgctt acaatttgta
    17941 agcagttgaa aatgaaagca acagatggaa aaatgcgttt aactgatgta gcagatatgc
    18001 aaggaatatt ccgtattatc cagtccatcc catcccctaa agcagaacct tttaagttat
    18061 ggcttgctga ggttggaaaa gaacgaattg atgaaattat cgatcctgaa cttacgattg
    18121 acagagcctt agaaacttat ctaaagaagg gatatacacg tgagtggata aatcaaagac
    18181 ttcaagccat tcaggtaaga aaagaactga ctgatgcttg ggatgaccat gggatacaaa
    18241 aaggcaaaga atacgcaatt cttactgatg aaatcaccaa agcatggtcc ggaatgacaa
    18301 caagaggtta taaaaatctg aagggtttga aaaaggaaaa tctaagggat aatatgacca
    18361 ctcttgaaat agttcttaat atgcttgcag aagc
//
LOCUS       DARYJX010000043        18175 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYJX010000043 DARYJX010000000
VERSION     DARYJX010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18175
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            62..298
                     /locus_tag="TU257_001631"
     CDS             62..298
                     /locus_tag="TU257_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL0834628.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TU257_001632"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TU257_001632"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0834629.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TU257_001633"
     CDS             1637..1825
                     /locus_tag="TU257_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0834630.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TU257_001634"
     CDS             1857..2735
                     /locus_tag="TU257_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0834631.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TU257_001635"
     CDS             2749..2907
                     /locus_tag="TU257_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834632.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TU257_001636"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TU257_001636"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL0834633.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4701..4886
                     /locus_tag="TU257_001637"
     CDS             4701..4886
                     /locus_tag="TU257_001637"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834634.1"
                     /translation="MVKNQIISLKKELTLNLELFFGLESERKKTGKEQRSDWLAYLKQ
                     VLGRSLISAHYSIEGLC"
     gene            4880..7285
                     /locus_tag="TU257_001638"
     CDS             4880..7285
                     /locus_tag="TU257_001638"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL0834635.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TU257_001639"
     CDS             7520..8596
                     /locus_tag="TU257_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834636.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TU257_001640"
     CDS             8606..9310
                     /locus_tag="TU257_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834637.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9649..10773
                     /locus_tag="TU257_001641"
     CDS             9649..10773
                     /locus_tag="TU257_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL0834638.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10935..11528)
                     /locus_tag="TU257_001642"
                     /pseudo
     CDS             complement(10935..11528)
                     /locus_tag="TU257_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11597..13570
                     /locus_tag="TU257_001643"
     CDS             11597..13570
                     /locus_tag="TU257_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL0834639.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13594..15036
                     /locus_tag="TU257_001644"
     CDS             13594..15036
                     /locus_tag="TU257_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL0834640.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15117..15926
                     /locus_tag="TU257_001645"
     CDS             15117..15926
                     /locus_tag="TU257_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL0834641.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16238..17395
                     /locus_tag="TU257_001646"
     CDS             16238..17395
                     /locus_tag="TU257_001646"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0834642.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17481..>18175
                     /locus_tag="TU257_001647"
     CDS             17481..>18175
                     /locus_tag="TU257_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0834643.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT         5634 a         3657 c         4096 g         4788 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaaatgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ctcaaaagtt ccttttactg atatttaata ttttctgtat ttttaattta
     9421 tagaaaaata aagaaacatg ctgagagttg atcaaaacac ttactatact tacgatgaca
     9481 agtaacttgc taaagtaatg gttgacatat aattgtaaaa aaacagaaat aaaaaaaaaa
     9541 cggtttaata ttgacctaat tggcaataac gtttacaata aaggtataat tatctgccgt
     9601 tgataattag gagacatcat gtctagataa aaacaaaagg ggaataaaat ggcaaaaaaa
     9661 gaaatgaagt tttaccttcg taaatcagcc tttgggctag cttcagtatc agcagccctc
     9721 ttggttggtg cggcagctgt atcagcagat tctgttgagt cagctgggcc tgtagcagtt
     9781 gctgttacag atagtttaga tagtgaagcc gcagctacaa aggcagaagc tgatctagtt
     9841 gctgcaaaag cagacctagc agcagcagaa gtagcaatca cagctgcaaa agctgaattt
     9901 gacaccgctc aagcagacct agctaccgct gaagctacta tcgcagagct tgagcaaaaa
     9961 attcctgagt tagagaaaaa aattcaagaa gctcaggaaa aactaaacta tgaaaatcga
    10021 ccatcaccta aacgtgtggg cagtgatgat gaagatgaca cagtagctag aaagcttatg
    10081 tcagaaaagg aagctcttaa ggctgagctt caaaagacta aagaagcgct agatacagct
    10141 aaaagagctt atgctggcat cgaagaaaga aaacaagtag cagcaactaa gctagatgca
    10201 gctaacaagg cttttgctgg agttgaagaa aagcatgctc aagcaatggc tgcatttgga
    10261 gcagcattcg cagcatacaa ggaagctgtt aaggctgaat tgaaggcagc aggtgctagc
    10321 gacttctaca ccaagaagat tgactctgcc gacacagttg acggtgttaa gacactcaga
    10381 gaaatgatct tagactcaat tgctaagcca gaggttgaac cagaggctaa gcctgaacct
    10441 aagccagaac caaaacctga gccaaaacct gagccaaaac cagaacctaa gccagaacca
    10501 aaacctgagc ctaagccaga gccaaaacca gaacctaagc ctgagcctaa gccagaacca
    10561 aaaccagaac ctaagccaaa acctcaacct aaaccagctc cagctccaaa acctgaagct
    10621 aagaaggaag agaagaaagc agcgcctaag caagacacca acaaattgcc atcaacaggt
    10681 gaagctacaa atccattctt caccgcggca gctcttgcag ttatggcagg tgcaggcgtg
    10741 gctgcagtgt caacaagacg caaagaaaac taagccttat accccagtgg taaagcttga
    10801 gcgagaacaa tttgttctcg cttttttagt gtcttaaaag cacctacagc aatcataggt
    10861 gcttaacaag atatgtctaa cgattgctat cagctgtaga gaataaaaag gagagactaa
    10921 gccttgctca caagctactt agaccgaagg agctttagga tttctatgat ttgctgaggg
    10981 gagtccttac agccgcagct gatccactta atgatgatga cctcaataga ggcaatgtat
    11041 agctcaaaaa catatttttg ggtaacttca ggataatctt gtgattctgc acaattcatg
    11101 aggttggaat aggaaataat atccctaata taatgattaa aaattttata aatattagga
    11161 taataaagga ttaagctttg catgacctcc tgattgtcag agaggtagtt taggattttt
    11221 aaggtaatag ttgtatcaag tgatggggat tggtaaatga tagaggtgat atcatctagg
    11281 taaacgccga tcatttccct atctaagtcc ttcttagagt tgaaataatg ttaaaaggtt
    11341 gttcgactga tattagaagc cttgctaata tctgatacag taatactgtc cttatccttg
    11401 tattgtagta gtcggcagta gcttttaatt atttttttac aagtttgttt atttttatcc
    11461 attgtatcat taactcctta aaattgaaca ttaatgttaa ttttgtacat aatatttttt
    11521 gctaacatta tacaatgatg aacgtgattt gtaaaattaa attttgcaaa tcaataatgt
    11581 aaaaggagga ttttgtttga aacaactgac aaagatcgtt agtgtggtct tgttgctggt
    11641 ctttaccctt agtgctagcc tgcacaaggt tcgggcaact aatcttagtg acaacatcac
    11701 atcattgacg gttgcttctt catcactccg agatggagag agaacgacgg taaaggttgc
    11761 gtttgatgac aaaaaacaga aaatcaaggc aggggatacg atagaggtca cctggcctac
    11821 aagtggtaat gtctacattc agggctttaa taaaaccata ccgcttaata ttagaggggt
    11881 agatgttggt accttggagg tcacgctaga caaggctgtt ttcacattca atcaaaatat
    11941 tgaaacaatg catgatgtct ctggttgggg agagtttgat attactgtta gaaatgtgac
    12001 acaaaccacc gctgaaacat caggaacgac cacagtaaag gtaggcaatc gcactgctac
    12061 tatcactgtt actaagcctg aggcaggcac tggtaccagc tcattttatt ataagactgg
    12121 tgatatgcag cccaatgata ctgagcgtgt gagatggttc ctgctgatta acaacaacaa
    12181 ggaatgggtg gccaatactg ttacagtcga agacgatatt caaggtggtc aaaccttgga
    12241 tatgagcagc tttgacatca ccgtatctgg ttatcgtaac gagcgcttcg ttggggaaaa
    12301 cgctctgaca gagtttcata caacatttcc aaattctgtc attacggcaa cagataatca
    12361 cattagtgtg cggttagatc aatatgatgc ctcacaaaac actgtcaaca ttgcttataa
    12421 gacaaagata acggactttg accaaaaaga atttgccaac aacagtaaaa tctggtacca
    12481 gattttatac aaggatcagg tatcgggtca agagtcaaac caccaagtag ccaatatcaa
    12541 tgctaacggc ggggttgatg gcagtcgcta taccagcttt actgtcaaga aaatttggaa
    12601 tgacaaggaa aatcaagacg gtaagcgtcc aaagactatt actgttcagc tttacgccaa
    12661 tgatcagaaa gttaatgata agaccattga attgagtgat actaatagct ggcaagcaag
    12721 ttttggtaag ctggataagt atgacagtca gaaccaaaaa attacctaca gtgtcaagga
    12781 agtgatggtt cctgttggct accaatcgca ggttgagggg gatagtggag taggatttac
    12841 cattaccaac acctatacac cagaggtcat tagcattacc ggtcaaaaaa cttgggacga
    12901 cagggaaaac caagacggta aacgtcctaa ggagattacg gttcgtttat tggcaaatga
    12961 cgctgcaact gacaaggtag caactgcttc agagcaaacc ggctggaagt atacatttac
    13021 caatctaccg aaatacaaag atggtaaaca gatcacctac acgatccaag aggaccctgt
    13081 ggcagattac accacaacca ttcagggatt tgatattacc aatcatcatg aggtagcctt
    13141 gaccagccta aaggtcatca aggtttggaa tgataaggac gattattacc ataaacgtcc
    13201 caaggagatt accattttgc taaaggcaga tggcaaggtg attcgtgaac atcagatgac
    13261 accggatcag caaggaaaat gggaatacac ctttgaccag ctgccggtct atcaggcagg
    13321 caagaaaatc agctacagca ttgaggaaaa acaggttgct ggctatcaag cccctgtcta
    13381 tgaggttgat gaaggcttga agcaggtcac tgtaaccaac acccttaacc caagctacaa
    13441 gctgcctgac accggaggac aaggagtgaa atggtacctg ttaatcggtg gcggttttat
    13501 catcgtcgca atccttgtac tgatcagcct ttatcaaaaa cacaagcgcc ataacatgtc
    13561 aaaaccataa catgtaatag aggagagaga gctatgaaaa caatcaaatt aatcttgacg
    13621 agcttgcttg tcaccttcct aacaatgctg tcaggaaagg catttgctga tacagcaagc
    13681 tataccatca ctgttgaggg agctacagca ggtcacacct atgaggctta tcagattttc
    13741 aagggtgact tgtttgacag taccctatca aacatcacat ggggaggtgg tgttacacct
    13801 tttgaatttg atggttcaaa agacgctgct aagattgcag agggattgaa ggaagcaaat
    13861 gcagctgcct ttgccaagga agcaggtaag cacttgacag caaccattgc aggaacagga
    13921 acacatgcaa tcaccgttaa cgaggctggc tactacctca tcaaggacaa aaatgattct
    13981 caaacaggca agcatgacgc ctacacctca tttgtcctga aggttgttaa aaataccagc
    14041 ttcaaaccaa aatctgctat cccaacagtc cttaaaaagg tcaaggaccg taatgacaag
    14101 acaggtcttg agacaggctg gcaagattca gctgactatg acaaaaatga caaggtgcca
    14161 ttccagctaa ccgcaaccct accgtcaaat tacgatgcct ttcaagaata ctaccttgaa
    14221 tttgtagata ccttatcaaa agggctaagc tacaacaaag acgccaaggt ctatgtggtt
    14281 aatggagata ctcgtcaaga tattactaat tcatttacag ttagtgaaga tggttcatct
    14341 tttaaaatca ataacctaaa ggctgttcag ggagtaacaa taacagctac cagtaagatc
    14401 gttgtcgaat acactgctac cctcaatgac caagcggcca tcggcaaaaa aggaaatcca
    14461 aacgaagttg ctttgaaata ctcaaacgat ccaaacgctc ttggaaaagg agaggagtct
    14521 ccaaaagggg agacaccaaa agacaaggtt atcgttttca cctataaaac tatcatcaat
    14581 aaggttgatc aagatcaaaa agccctaaaa ggtgcaggct ttacccttta taagctggtc
    14641 aaaggtgata atggcgagga aaaatatcaa atagtccaag aaattaaagc aggggataca
    14701 actagctttg agtttgttgg acttgacgct ggtgattaca agctcagcga aacaacaaca
    14761 cctggcggtt acaacactat tgcagatgtc atgttcagca ttgtagcgca gcatgaaacc
    14821 gagtcagacg atcctcagtt gactagccta accgttgaca aagcaactgg cttcactgct
    14881 gatacagaag ctggtaccgt atccgcaact attgttaata aaaaagggtc tatcctccct
    14941 tcgacaggaa gtatcggaac aaccatgctc tatgtgtttg gagtaatgct aatgacaata
    15001 tcaacgctgt ttatctttcg tcagaaacag caataagatc gtgtgagtag gtaaaaagaa
    15061 gtggatagac gtcttaccaa gacctattca cctctttttt tgatagaggc tatagaatga
    15121 agaaaagtgt cattttttgg agtgtgattt tggtggcagg ctgtctgatt gtcctttacc
    15181 ccacccttag taactattgg aatgcacagc accaatcaca gctcatcgct gactatgtct
    15241 caagcacgca agctttgaga cataaggata gtcagctcat gctagaagca gccaatcagt
    15301 acaatcagca gctaaaagct aaccatgatc ctgatttaac cttgaccgat agtgaggcag
    15361 aagcctatca gcagcagctg gatctgacaa atacaggtat catggcctac atagatattc
    15421 caaaggtgca tgagcggctg ccgatttatc atggcaccga tgaggagatc ctacaggtgg
    15481 ctatcggtca tcttgcaggc acctctttgc ctgtaggtgg caagggaaca catgctgtca
    15541 tctcaggaca tcgagggtta ccctctgcca agctatttac caatattgat aagctgagga
    15601 ttaacgatac ctttaccatc accagtctta ataggactat gacctatcag gtggataaga
    15661 ttgctaccgt tttgcctgat gatgtcagcc tcttaaggat agaggagggg aaggatctgg
    15721 taaccttggt cacctgtacc ccctacggtg tcaacacgca tcggctcttg gtcagagggc
    15781 atcgtatcaa aacagcgaca ccaaccgctg caagaggatc tcaaaagcct agtaggctaa
    15841 tcctctggct cttgctaatc agtgcattag ggctatctct cgtactaata ggcacttggc
    15901 gctggcgtag gaggtctaaa gcatgagcag gctttccaga agcaactaag tcaaatcatc
    15961 aacccttgat aggttactga ggacctatca ggggattttt tagtgctaaa ttgcgactat
    16021 gattaaaaac acagaaatcg tttttttttc ttagtgaccg aaaacgcttt aaaagagcga
    16081 gcatttggag ccttcaaaag tgacatctga gcataacatg ataaaattga cttataaaac
    16141 ctaataaaat gataaaagga ggagagttaa cgacaaaata ttagatattt atttaatttg
    16201 ttgtttttga aaacgtttta taataagaaa ggatagcatg atgaaaaaac aatcattcac
    16261 acactcacgt aaacctaaat tcggtatgag aaaattatct attggccttg cctcatgtat
    16321 gctaggaatg atgttcctaa caacaggaca tgtttctggt gaggtagttg aagtttggcc
    16381 taatgggcaa aatcctaatg gtaaaataga aattctaagt caaactgagc actctgagca
    16441 tttacagaaa ttacgcgata ttgaagattt ccaagctcaa aagcaagctg atcatgttcg
    16501 ttacactaaa tggttagatg gggtaactgt tgatgagcat gaattcagaa aaatcaagga
    16561 atatgacaca gaatattatg taacacctct tttaagtggt aaaggttact atgatatcaa
    16621 taaagatttc aatcaagata gtgataaatg tgctgccgct gtagcggcta atatgttcca
    16681 ttattggttt gatagaaata gagacagtat taatcgtttc ttaagtcaaa gtccaggtga
    16741 aaatggtgtt attaaacttg aaaatgaaaa aacaatagaa gtatcaaaat ttttagaaac
    16801 ttaccgtagt gatggtgatt atcttgataa aagtccgttt tttgacctta tcagtaacag
    16861 ctttaaaggt cctgtttggg caaataagct attggatgct tacattaacg gctatggtta
    16921 tatccataaa tttgctaaaa atactccaca ttctaaaaat aataatagta aatttaattt
    16981 ctttaaaaaa gtatttgatg gtaatctctt gacagatatt caccaaattt ttgattataa
    17041 cactttttca gataaattaa gtgaggctct ctatactggt aaagccattg gattggccta
    17101 cggacctgga gacttgcgtc gttcactagg tcatattatt tctgtctggg gagctgatct
    17161 tgacgatcag aatcgcgtgg tagctattta tgtaactgat tctgatgata aaaagttaac
    17221 tataggaaat gagagagttg gtttgaagcg atataaagta tctagcgatg atcaaggtcg
    17281 tgctcgtctg acgactcgtg ataaagataa cacaggtggt gaaattcgat ctattgaaac
    17341 attagatatg ggtacacaag agtgggcaga ttacttcaac aagacagaaa aataacaata
    17401 acccctacac atatatgatt actccagata aagcacacag caatagactc agccagtaag
    17461 gaaaggacga taacaaaacg atgctaacaa accaaacggg gtacaggcat agacttagta
    17521 agcagaagct acctatcagc atggtttcct gcttgctagg aatgggggtg ctaacctctc
    17581 caacattaat ctcagctgat gatagttctc ctactatcat cattaaatcg ggtgcaggta
    17641 tgacaattga tcctcaatta ccgaaaactc tcctttctaa acccgaagag aaaccagagg
    17701 aaacacctaa acttccagat gagcgacatt atggtgatga tgtcagaccg gaagaaacac
    17761 caaagcttcc agacgagaga cattatggtg acgatataaa accggaagag atgccaaagc
    17821 tcccagatga gcgacattat ggtgatgaca tcaggaagcc gaaaccggag gatactccaa
    17881 agccacctaa tgaaagcggt caaggtaatg acttaaaaga agatttggag cttaaaaagc
    17941 aacgtcgaga gcttacagag cagcttcgtg ctttaaaaac tattgaggaa gttttagagt
    18001 tcctgagaaa accaattcct ggatttgtaa cagatgaaga ttggaatttc ttagtatcat
    18061 ttgtagaaaa aggcccagaa aataaaactt ttgaagtaga taaattaaaa ttactagaaa
    18121 tcttctcaac ctcacaaggt catagagttt ggttaggtta ccttattctg gaaga
//
LOCUS       DARYJX010000044        17927 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYJX010000044 DARYJX010000000
VERSION     DARYJX010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17927
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            39..266
                     /locus_tag="TU257_001648"
     CDS             39..266
                     /locus_tag="TU257_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834644.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            270..692
                     /locus_tag="TU257_001649"
     CDS             270..692
                     /locus_tag="TU257_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0834645.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            860..1090
                     /locus_tag="TU257_001650"
     CDS             860..1090
                     /locus_tag="TU257_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834646.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            1467..1901
                     /locus_tag="TU257_001651"
     CDS             1467..1901
                     /locus_tag="TU257_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL0834647.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            2439..2513
                     /locus_tag="TU257_001652"
     tRNA            2439..2513
                     /locus_tag="TU257_001652"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            2672..3163
                     /locus_tag="TU257_001653"
     CDS             2672..3163
                     /locus_tag="TU257_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL0834648.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            3198..4451
                     /locus_tag="TU257_001654"
     CDS             3198..4451
                     /locus_tag="TU257_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0834649.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            4461..5960
                     /locus_tag="TU257_001655"
     CDS             4461..5960
                     /locus_tag="TU257_001655"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0834650.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            5960..7570
                     /locus_tag="TU257_001656"
     CDS             5960..7570
                     /locus_tag="TU257_001656"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834651.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            7536..7757
                     /locus_tag="TU257_001657"
     CDS             7536..7757
                     /locus_tag="TU257_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834652.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            7809..8093
                     /locus_tag="TU257_001658"
     CDS             7809..8093
                     /locus_tag="TU257_001658"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834653.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            8179..8418
                     /locus_tag="TU257_001659"
     CDS             8179..8418
                     /locus_tag="TU257_001659"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834654.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            8403..9005
                     /locus_tag="TU257_001660"
     CDS             8403..9005
                     /locus_tag="TU257_001660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834655.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            9007..9879
                     /locus_tag="TU257_001661"
     CDS             9007..9879
                     /locus_tag="TU257_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834656.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            9890..10138
                     /locus_tag="TU257_001662"
     CDS             9890..10138
                     /locus_tag="TU257_001662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834657.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            10141..10527
                     /locus_tag="TU257_001663"
     CDS             10141..10527
                     /locus_tag="TU257_001663"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834658.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            10521..10865
                     /locus_tag="TU257_001664"
     CDS             10521..10865
                     /locus_tag="TU257_001664"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834659.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            10862..11215
                     /locus_tag="TU257_001665"
     CDS             10862..11215
                     /locus_tag="TU257_001665"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834660.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            11218..11586
                     /locus_tag="TU257_001666"
     CDS             11218..11586
                     /locus_tag="TU257_001666"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834661.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            11590..12087
                     /locus_tag="TU257_001667"
     CDS             11590..12087
                     /locus_tag="TU257_001667"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834662.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            12110..12514
                     /locus_tag="TU257_001668"
     CDS             12110..12514
                     /locus_tag="TU257_001668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834663.1"
                     /translation="MRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEIE
                     ELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLLD
                     YLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            12528..13139
                     /locus_tag="TU257_001669"
     CDS             12528..13139
                     /locus_tag="TU257_001669"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834664.1"
                     /translation="MTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVNDYA
                     KIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMHFE
                     KDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPNKD
                     EASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            13140..15587
                     /locus_tag="TU257_001670"
     CDS             13140..15587
                     /locus_tag="TU257_001670"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL0834665.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            15591..16352
                     /locus_tag="TU257_001671"
     CDS             15591..16352
                     /locus_tag="TU257_001671"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL0834666.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            16363..>17927
                     /locus_tag="TU257_001672"
     CDS             16363..>17927
                     /locus_tag="TU257_001672"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834667.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDP"
BASE COUNT         5844 a         3120 c         4092 g         4871 t
ORIGIN      
        1 agacaccgat acacttgcag cagtacggga ggctgatcat gactaaaaac gactttttaa
       61 caggttttgt acttatactt ttagctgctt gcatttttgc agcaggattt gtgattggat
      121 ctgactgtag tagcgagcac tacgagcaac aaatgacagg cttgcgtatg cagcttgtta
      181 acacgcagca gcagcttaag cgtgcgagtg aggatagagc aaggcggact aaaaggattg
      241 cggatctgac cgggaatgga ggatagggta tgatcgacga aatcgaactc gacctacaaa
      301 aaccagaaat cccacagttt gtcgctgact acatagatga tatgcacaaa aacgcacgta
      361 cattgagata cgcttttaaa tacatggaaa gtaacataaa aatgcacaaa tggtgtgttt
      421 ttgaaaggca agaaacgttt gttaatgctt ttttatacgg ctacacaata aaaaaagaaa
      481 agctgtatat tgttgagatc cctaatccta atagtggcat agaacacaaa catattgcac
      541 tagcaaggtt agcgaatgga aaacttggat tttcagagat catagatact gatttttatt
      601 caagagaaga tgtccgactc accgagtcag aaatccgcaa agattttgat tgggcatgga
      661 gagaggggtt tgctaaagag gtgacggaat gagcagagat aaaaccagaa tcaggaacat
      721 tgtgaagtcc atgaaacagt taggtgctag cgaagaagag acagacgaat acatgtatct
      781 atgcgtgttt aaaaagcctc acgtcatagc tcaaatccgt aaaaaggcta agattttcag
      841 aggcgaaggg tggtaacaga tggcatattt acgagaagaa agagaaacag ttattcatta
      901 cgacgaattg gatgactgct ggacttttga aactaacgtc cgtaggcata ttacgaaaat
      961 agaaaaacgc atcgaactgt acgagattct ctcagaggaa ttcgatgacc gaggaaggcg
     1021 tatctatatc tgtgcgaaaa tgaagacagg aactgtcagt ccctttgcga aaccaccaag
     1081 aaggaaatag ctatagaatc gattttaagc ttcaaaaaca tggcaagaac gcacttctgg
     1141 gaacgtgaaa cacctagcta atataaatgt accctagaac aatttaaatc gaaaaaatga
     1201 ttagctacat aggttttaat cggcttatgt ggcatagacc gaaattaaac acagaaggat
     1261 gtgatgacaa tctccttaca cccaaaaaat ctaacgctgg ttatcggtca ccagctatta
     1321 tccaaggcgc taatactgac atcgtgtgcc tgagctggct tataaaaaac gaaagagagg
     1381 gcttttctcc acacaaaaag acgtccatgc gaacgcctcc ttggttatat ctgttaacac
     1441 cattatacca cactgagggg gctttcatga cgttttttcc tgagattgat atccaaaaaa
     1501 caaaatccaa tgccaagcgt aaattgaaag agtatccacg ctggcggcgg atagctaacg
     1561 atgtagatac tcaaaaagtt acagctactt actcatttga gccaaggcaa cctcatggag
     1621 tccatagcaa gcctgtagag aggttagcac ttaatcgtgt gtcagcggag caggagttag
     1681 atgcgattga gcaagctgtc agcatgatac tagagccaga gaggcgcagg attttgtacg
     1741 ataaatactt atcaccttat aaaaaagcgg acaaggttat ttatacagaa ttgtgtatgt
     1801 cagagagctt ttattatgat acgctcgata tcgctttatt agcttttgca gagctatata
     1861 gagaggggtc tctgattgtc gagcaaggag tttttagcta gtttttatac agtaatataa
     1921 tagtttttgt acaaaatagc gtgttaatat agtatcatag caaaataaca aaaagagata
     1981 accattttac caattgacta tttatttagt cgccaacttt aactacgatc aaacttgtta
     2041 ttttgaaggt acatgggacg tgcaggttcg aatcctgccg tctcaatacc agctatttcc
     2101 aaaatggaaa cagttggaaa agacaaaccc cccattcctt taaaggcaga tacgttctga
     2161 tatggggctt tttatgatta actgcaagta aaacaagggt cgcaaccttg cttgtggtta
     2221 gtagacctag tggtcgttta tgcacgttcg attcgtgcaa ggtctgttgg gttgattgca
     2281 ataatccttt tgtggacgca caacaaaaat gtgatgtaag tcacggctaa ggtttgggcg
     2341 gcgatagaat agatgcgcaa ctatcgttgg gtcacgtctc agagtttgca tagttaatat
     2401 taaccgatgg gcacaccctg cgtcagtggg ttgtttatgg atagcttagc aaaggggtta
     2461 atgcgaccaa ctgtttagtt tggtaggcgt gagttcgaat ctcacactat tctttcagga
     2521 acatgaaccg tgattggaaa acggtagagg tagcgccttg ataattggat tgtcgacggt
     2581 ctgattatat gtgtcggttc aattccgact gttcctgttc tagtcaccaa ttgtggtggc
     2641 tttttattat gtcacgagga ggtgatggaa aattgctaag ttaactataa aacaacaaaa
     2701 atttattgat gagtacatca tctgtggaaa tgcgacagaa gccgctctta aggcgggtta
     2761 tagcaaaaaa acggctgggc aaatcggtga gcagaacttg aaaaaacttg aaataaaatc
     2821 tgccatcaac gaacggctaa aacaactcga aagcagtaaa atagctagtg caatcgagat
     2881 cctacaagtt cttactgccg ttcttcggca ggatttgacg gaggaggttg ttacccttaa
     2941 tcctgtaaca ggtgagtacg ttactatgca gaaaaaacct agcatcgcag aagtcataaa
     3001 agctgctggt gagttattga aacgttatcc tatccaagaa caaattgaaa aaatcaagca
     3061 agaaaacgag ttgttacgcc ttaaaattga aaccgtcaaa ggcgccaagc ctgataccca
     3121 tttgatggaa aaactgctgg aggtaatcga agatggcggt taggataaaa aagttatcca
     3181 caaaacaaaa agacatcatt agacgccctt ttaactacga attagaggtc aatgagggaa
     3241 cacccagaag tggaaagacc accgctgggc attttcgtta tgctaggtat ctgattgagt
     3301 cagaagatga aaatcatctt gtgactgctt ataatcaaga acaagcttat cgtttgttta
     3361 ttgatggaga cggtacaggg ctgatgcaca tctttgacgg gaactgcgaa atcaaacatg
     3421 atgagcgagg agatcacctg cttgtaacaa caccaaaagg taataaaagg gtttattaca
     3481 agggtggagg taaagttaac tcagtcggtg ctattacagg tatgtctcta ggctcagtgg
     3541 tcttttgtga gattaatcta ctgcatatgg attttatcca ggagtgtttt aggcgtacct
     3601 gggcggctaa actgcgttat cacttagcag accttaaccc tcctgcgcca cagcaccctg
     3661 ttattaaaga cgtttttgac gtccaaaata ccagatggac gcattggacc atggacgata
     3721 atccaatatt aactgcggag cgcaagcaaa acattatcaa tagcctcaaa aaaaatcctt
     3781 atctttataa acgagatgta ctcgggcagc gggtgatgcc tcaaggtgtt atttatggtc
     3841 tttttgacat ggaaaaaaat gttctagaca ctttgattgg cgagccagtg gagatgtatt
     3901 tctgtgcaga tggtgggcaa tctgatgcca catctatgtc ttgcaacatc gtaacaagag
     3961 ttagagataa tggcaagata agttttaggc ttaatcggac agcgcactac tatcatagtg
     4021 gagcagatac tggtcaggtc aaagccatgt caacatacgc cagagaactt aaggctttca
     4081 ttgactggtg tgttaaaaaa taccaacttc ggtactctga tgtctttatt gaccctgcgt
     4141 gtaaggcttt gcgcgaggaa ttacatgcca ttggtattct gacgactgga gcgccgaaca
     4201 acgctcacga cgtaaacagt aaggcgaaag gtatcgaagt tgggatagaa cgtggccaga
     4261 ctttgatttc agacggtgat ttttatctag taaatcacaa agaggaaaaa tatgatcatt
     4321 atcatttcct gaaggaatta gggctttata gccgcgatga taaaggcaaa ccaatagacg
     4381 caaacaacca ctcaatggac gaatttaggt actcggtcaa tgtttttgtg ggacgataca
     4441 aaatgaaata ggaggtagtc atgtttagaa acctctggac taaaataaaa ggggtgatgc
     4501 aaaaaatggg attgataaaa ggtttgaaag atttgaacct gcaccgcgaa attgaactgt
     4561 ctgataagca ttatgatagt atccaaattt ggaaagagtt gtatcaaggc tatcacgata
     4621 aaatacacga ttactatgag aaatctatct tagatggtcg taaaaagaag aagcgtttga
     4681 ctttgaatat gcctaaagtt gtgacctcag agcttgctac attgattttt aatgaaaaat
     4741 gtgaaattaa cattggttct gaaaatgaga gtttgacaaa gctcatcact gaaacgttag
     4801 agaaaaataa ttttactcag gagtttcaac gcttcttaga atatagtttc gccttgggag
     4861 gtatggcaat caaagcatat ctcaaaaagg acggtactat cggtcttaat tttgtacaag
     4921 cggatagttt tattcccatt tcgtgggata atgctgggat tagcgaagcc gtatttgttg
     4981 atacgcagca tcgtggaaaa tacaagtaca cgcatttgga gtggcatact tgggaaagtg
     5041 agttgtatgt agttgctcac gagttattta gaactgacaa gtcaaatgat gatgttggca
     5101 ttcgcgtacc gataacagag atttatccag atttaaaatc acaagtagtc atcgaaaaac
     5161 tatcaagacc gctatttgtt tacctcaaac ctaattcggc aaacaacatt gatctatcaa
     5221 gtccgctagg gatttcaatc tatcacaatt cgtttgatac cttgcgagcg attgatattg
     5281 cctacgatag ctttgagcgt gagtttcgac ttggccgtaa gaggatattg gttccagcga
     5341 ctgccattcg tactgtagtg gatagcgagg ggaatttcca ccgctatttt gacgcaacag
     5401 acgaaacata tgaggctttc cacacaggtg aagacagcaa aattcaagat atcaaagata
     5461 ttagtgttga attgcgagtt gatgaacata ttgcagctat taacgcactg ttgaacttac
     5521 ttagtatgca gattggcttt agcccaggtt ctttcagttt cgatggagta tcgggtgtca
     5581 agacagccac cgaggttatc tctgagaatt ctaagacatt ccgcacgaag caatctcatg
     5641 aaacgatggt agaagcaaca ttgaaaaatc ttgttgcgat tatcgttgat tttggggatc
     5701 tttatggttt gatcgagggt gagagtaagt ataatgtaac tgtaacgttt gacgactcta
     5761 ttgcgcagga cagaacccag gacgctcagt attatatagg gttggtcgca gctgggttaa
     5821 tcagcaagaa aaaagctatg atgaagctgt ttaatctgtc agaagaagat gcagagttgg
     5881 aaatccaaac tatccacgag gaaagccgga caacaaacga tatgtcaatt gatttatttg
     5941 gtttggacgg tgatgcttag tggattatga tactcatatc cagctgtctt ttgacttaat
     6001 agagctttat tctgatgtcg aacgtgaatt gttgacgtca ataggtcgca ggtttgcaaa
     6061 acactatgac gaaatggtag ctggcgacat catggattgg caaattaggc aattactcga
     6121 agttggagag ctgagaaaag agcacatcga aatcatgcga aaaagtgcac gcgtgagtcg
     6181 tgagcgtatg attgagatgc tgacggaggc aggttatacc tccgcaggaa ggtatgagga
     6241 tttttttaaa gaggcatacg ttaaaggttt aatcaagctc aatccatctg ctgcagacaa
     6301 cagcatgagg ttgttgcgag tgttaaatac ttacatcaat caagctgagg acacacttaa
     6361 tcttgtcaat acgaccatgt tacagtctgg ccaagatact tttttagata cagtcaatca
     6421 agttgttgct tatgtttcta caggtatcaa gaccccacaa gttgctatgc gtgacgctct
     6481 aaaaaatgct ggtcaaaagg gccttacagt ctttcgtgct aaaaatggcg cccagtggtc
     6541 aacggagact tatctcaata tgatcactcg gacgatgaac tctaacattt ctaacgctat
     6601 ggaagatgag cgtaggcatg agtatggtgt tgattacatc gaggtatcta gccatgctgg
     6661 cgcacgtcca aggtgtgctc cttatcaagg tcggatatat tacgatggtg tcggagatga
     6721 tccgctagag aaatacccgc acttctcaga gacttcttat ggcgaagctg ctggattgtt
     6781 tggcgttaat tgcggtcatc ataaatatcc ttacgtccca ggtatgagta aacagacctt
     6841 tttcccttac agtaaaagcg aaaacgataa aacctatgca gagtcgcagg tacaacgtaa
     6901 attagaacgg gaagttaagc agctgaaacg ggaacgagca attctaactg ctgcgaagga
     6961 caaagagggg gctaaattag cttctcaacg cttggagaac aagtggcagg aattgcgtca
     7021 gtttactgct caaacaggca gaacgagacg atacgaccgc gagaaatcgc taaatactat
     7081 tttgtctgag gacaagaaaa aagccattgt caaagataat ttgaaaatca gagatgagta
     7141 tcgagcgatt aagaaagcta tccctgaagt agctcctaaa aatcttgaaa cctattatga
     7201 tatgcgttat aatggtggca agatatacga ggatttagtt agggattaca aagactatat
     7261 aagatggtct aaagctgaat ttcctactaa aaaatctttt gaagggcata ttgatagtca
     7321 cttaaaagag tttccaggat tgactggtaa acaatatcag aaaaaggctg ctgacttatt
     7381 atctagaccg ataactgata atattttagg ttatgataca gattctagac gtgttaggta
     7441 tgacttagaa aataacattt ttgctttagg gcgcgttaaa caaggtacga ttacgactat
     7501 gctgaaacca aaggaagggg ttgattactt tgacaatgac tggaaaagag agtttgataa
     7561 tcttaaatga tttagaatat gtccattgtc ctgtttgtgg aactttgacc gaggtttatg
     7621 atatttgcga tacttgtaaa tggcagaata ccggtgagac aaatattgat ggcggtccta
     7681 attatattac acttgaggaa gcacgacgaa ggtgggcaaa tggtgaacct ttgcgcaact
     7741 tttttaaaga ccaataatac aagcactgta acagtgcttt ttttgtactc aaaaaaggag
     7801 agagtaaaat gaacaaacga attgaaaaga agcgtcgcac acaaatgatg ttagacagaa
     7861 tcttgcgcat tgtagaattg atgtcgcaag caactgacga caactttgct atcttggaaa
     7921 agcgcttaga aaaagctgaa aaacgtaacg aagagcttat ggaaatcatc ttagtaaacg
     7981 ttaaagaggt aaataaccgc tttgacgagc tagaaatctg ccagaagatt gttgaagatg
     8041 atgtcgcaga gctcaaaaaa gctaagaaaa aaggctggtt cagccggaaa taacttaatc
     8101 gtgtcgaatt cgatgcggtt ttattttgcc ctgccgcatg gcgataaact aggtaaaaat
     8161 aaaagaaaga ggtctaaaat ggctgttatt atcgtacaaa cacgaggcgg agatattgaa
     8221 gttcccaccc cattaccagc aatgcaagct aataaagcga ttcaaagtca attattcgat
     8281 aaggagctga cttttttatg cgtggataat catgcttttg ctaaaactga ggttttacac
     8341 gttttggtcg aaacagaaga agatgaagaa ttaccacagt caaaacataa ggaggaagaa
     8401 acatgctaca tggattaaaa caccgtttgt ttaaactagc cccagatact ggagcaggcg
     8461 gaggcgctga agttactagc gagactaacg ctgaagctgg acgagttgag caaacagtat
     8521 cgcaacaaca agctgatccg gttgatactg aggcaatcaa aaatcaagca attaatgagg
     8581 ttctaagtca actaggtgtt tcttcggtag aagatgccaa agcaaatcta gcttcttgga
     8641 atgaatatca agaaggtcag aaaacagagt ttcaaaaaat tcaagatagt ttgactgtgg
     8701 ctaataactc tttggctgag cgcgacacta tgattgctag cttacaagct cagttagctg
     8761 ctgctcaaat gggagtgcct gcggaaaaca cctccgatgt tatcactttg gccaatagtt
     8821 tggtccacga taaaacagac atcaatgcag cgattactac cgtacttgag aaatatcctc
     8881 atttcaaagg aggtgatgcc gatgtagctg ataaacctaa ctttgtgact caaactcaga
     8941 gtcaaacgga aacgacggaa gacgcttttt ttaaagcgtt aggactaaca attaaggagg
     9001 actaatatgt caatcaatta tattactaaa catgaaggaa tattcgaaaa gaaactaatg
     9061 caaggcgctt tgacgtctaa cttagagaca ccaaaagtca actggttagg tgcaaagtct
     9121 tttgagctac caaccatctc ggtgactggc tataaggcgc acacacgctc aaaagggtat
     9181 aacgcaggta ctgtatctaa cgataaaaat acttatacgc tcggctttga tcgtgacgta
     9241 gagttttttg tggataaggc agacgtcgat gagactaacc aagagctgtc tatggctaac
     9301 atctcaaaca cttttatcac agagcatgca acgccagaag ttgacgctta tcgcttttcg
     9361 aagattgcca caaatgcgat cgataatagc cattttaagc aggaagatga ctactctact
     9421 actaatgttt atgagcgctt aaaagctgct attttgccta ttcgcaagta cggagctggc
     9481 aatatcatta tctatgtctc cagtgagatt atggactttt tggagcgctc aaaggacttt
     9541 acacgctcaa tcgcgacaac atcaccgcaa gggattgata ctcgtgtgac atctcttgac
     9601 ggagtgcagc tcatagaggt ttgggacgat gcccgcttta agactaaatt tgattttacg
     9661 acaggctttg tcaaagatgg cagcggtaaa gacattaact ttttgattgt ggccaagcct
     9721 gcggttattg caaaagctaa atttaactct atttatcttt ttgcaccagg tcagcacacc
     9781 gaaggggacg ggtatctata tcaaaatcgc ttgtatcacg acctttttgt gcttaaatct
     9841 aaacaagatg gggtttatgt atcccataaa tcagcttagg aggttaacga tgaaaacata
     9901 cgagaaggac aatcaagtct ataaagtaca agaaggcagc gagctggaaa ttcagctgat
     9961 tgccgacggc tttaaagaaa ttattgaagc aaacgaaaag gaaactgata tcactaaaat
    10021 gaagcttgat aagctaaagg cttatgctga aaatgaaggc attataattc ctgaagatat
    10081 taagaaaaaa gaagatgttt tagcttttat taaggaacag cagcagagag gtgagtagtg
    10141 atgctcacct ttgattttta caataaggga tattgtggct cacagctgaa tgaagaaaag
    10201 ttcggggagc tgtcaaaacg tgctgagcgt aaaattttgg cacttattgg cttgaaaaag
    10261 gagcaagtga agaatttgcc acttgatatt ttagaggcgg taaaaatggc tgtctgcgcc
    10321 caaattgagt atcttaacgc aataggcgtt gaaagtgcta tcggagtaac ctctgtaacc
    10381 caagctaaag tcggcaattt tagttacaca gacggaaaga aagcgactgt atcagctagt
    10441 gttggctctg ttggtgttag ccctgacgtg ctagactatc tgcttccgag tggattgtta
    10501 tacaaggggg tgaatacgag atggtaaaag aagtcaaacc tatccctaaa gagttattag
    10561 ttgacacagt tacttatcta gcagttggca acaaagacag ctggggagca gaaacggtag
    10621 tatctacaga attgtcacag gtgttagtac aacctagaag cagtatccaa cgtgggcaac
    10681 aaaacgagag taatagctac gagttgttac tcttttttga ttgtgtaaac tcgttaccag
    10741 tagatcatca gtttaaggtt gacgacaaaa ttagttatct aggaaaagag tatcgtatcg
    10801 caagtgttga ggtactaaaa gcttttgacc agtcgccaca tcactatgag gtgatgctag
    10861 aatgataggt tttaaggttg aagtcatctt taacgctagt aaattgattg ccaagagtga
    10921 agcatctgca aagacagctc gctttgcttt aagtggtcaa atcaaaaagg atagtgacaa
    10981 gtatattcct gctcgtgagt ggaatctgcg agatagcgga agagtaactg aacgctcagt
    11041 atcttggcat acaccgtacg ctagacgact ctactacaat cctcagtata actttagcaa
    11101 ggataagaat ccgaatgcac aaggcaagtg gtttgaggtt gctaaagcaa atcatgcaga
    11161 gcattggtat gagctaacaa agaaagccta tggtgctgag tttagaggag attaatcatg
    11221 acatttattg attttttgct cagaaaagtt caagaagtga gcggagcgga accggtcctt
    11281 ggcattatgg ggaatagtga taaggttgct attatcccta tggctggaaa ttttgacaat
    11341 cgagctcttg acgaaagtaa gattaggatt tttactttcc aagttttggc caagagtaaa
    11401 aaacagcagg aagctttttt gacaacagaa aacttggtca atggtctaga cggtctatca
    11461 aatgagccgt ttactggagg atatctcatt aagctggagt gtacgacgac cactaacttt
    11521 gttgaaaaag atagtgacaa aaattattta tatacagctc ttttcagagc agaattagga
    11581 ggataagaaa tggcagcaga taagccaact ttttatttac aatccgagca taagctcgaa
    11641 atttcagaag atggaaaaac ttggatgcga ctagcaggtg gtatcagtga attagaacca
    11701 gacggaaatg aagaagtatc acaagatgct tatcttgacg gctctgaatc tgatgttaca
    11761 ggaggtcagc tagtactagc cttaactgga catcgtctag taggagataa agctcaagac
    11821 tggatctatg cacgtcaatt ccgatatggg ggcaaacgtc gtggttttac gcgttggaca
    11881 ttgccaggag gaaaaacaca gtttaccttt gcctctacgt ttgcaaatat caaaggtcca
    11941 tcaggagcgg ctaacggtaa aggtgaaatt gaatttgaaa tccattcgaa cgaaacactt
    12001 gtacctaata aagtagttgt agaagtcact aagacaaaca aagaacttgc gtctgaagca
    12061 cttggtttag aacgtcaaga gcgataagta gaaaggatag tcagcaatgg tgagacagtt
    12121 tgaatttaag aaaacggttg aagaaattga gattgcaggg gaaatctact tactgcctct
    12181 tgatgatgat aacctcttac gtatccaacg tgactttatt agttacggaa aagagatcga
    12241 agaactccaa aaagttgagg tagaaaaagg agatccagac gatctggcgg ataatcataa
    12301 gcaacagctt ttagtaatga aaaaggtcat cgagtcacca tttggagaag ggagttttga
    12361 gaaactttac gaagcatcag ggcactcttt aatgaatatg gttgacttat tggattatct
    12421 tgttgagtta gtcgctgaaa aagttgagca aaataaggct cgtgccacta aagcaaaaga
    12481 gaagtattac tcctcgaagc gcaagaaaaa gtaggtagct tatgaagttg acagaaacat
    12541 atgaagttct tgctgatgct tttgaatttg gcggtcatat cgtaactgtt gacttggctt
    12601 ttgatgtcgt gttgcgagtc atggagcttc ttgccgacgc agaagtcaat gactacgcta
    12661 aaattgtctg gactttggat atgctcttgc catattttga tcgtacggag ttaagttttg
    12721 atgaagaatt tgaaattttc gaatatatcc taaagacgtt tatctatgaa caagaagacg
    12781 gagaagatga cagtttagga ggaatgtcac aaacgaaaac aatgcatttt gaaaaggatg
    12841 cagagttaat ctttgcgtcc ttttttcaaa gttatcatct tgacctattt gaacaacagg
    12901 gaaaattgca ctggcgaaaa tttatgtcac tgctcatgaa tctgcataaa gacactcctt
    12961 ttaaggaagt tgtcagctat cgtgtcatga aagtgcctaa taaagatgaa gcatcggaag
    13021 agtatatcaa acacgtcaag aagatgaagc gtatctattc gctagaagac gaatctgagc
    13081 atcaagcgct aaatgatgac aagctttcag cgttagcagc aaggtttgga ggtgagtaga
    13141 tggcagatgg tagtgttatt attgataccc tgctaaagac tgagaaattt aaccaaggtg
    13201 tagggaaact acaaggtaaa ttagctggat taggatcaaa gttgaccagc attggtaccg
    13261 gtctaactct aggcttaact gctcctattg taggaatcgg agcggcatcg ctcagcacgt
    13321 ttactacatt tgaaagtcaa atgaatcgtg ttaaggcgat ttctggagca acagcaagtg
    13381 agttcagaaa actagaagac caggctatca aacttggagc ttcctctgtt tttagtgcga
    13441 cagaagtagc acaagctcaa gaaatgatgg cttctgcagg ttttaaagtc gtcgatatct
    13501 taaaagcaat gccgggtgtt atgtctctag ctgctgtatc tggtggggat atggcattag
    13561 caagcgaggc agccgcaaca gctgtcaata tgtttggact tgaagctaaa gacgcagccc
    13621 atgttgcaga tgtttttgca caagctgctg cggatactaa cgcagaagtt ggagatatgg
    13681 cagaagccct aaaatacgcc ggacctgttg ctggggcttt agggattagc ttggaagaaa
    13741 ccgcggcagc aattggtatc atgtctaatg caggcattaa agggtcacaa gcaggaacaa
    13801 ctttgaggac aagcctttca cgacttacgg atccaactaa aaagatgcga ggaatcatgt
    13861 ccgaattagg acttgaattt ttcgatgtta atggaaaaat gaagtcctta tctggtatta
    13921 ccaaagaact tcaaaccaaa atgggtgatt taactgatag tcaaaagagt gcagctatct
    13981 ctactttgtt tggtaaagaa gcaatgtctg gaatgcttgc cctagttaat tctgctcctg
    14041 gcgcattaga caagcaaaca caagcactta tcaattcaaa tggtgctgct aaagaaatgg
    14101 cagacaccat gaatagtggt gtcaagggat cgattgagga gcttaaaggt tcgcttgaga
    14161 ctgctggaat ctccataggt aaaatattgg cgccagccct aacgtcggtt atcggggcga
    14221 taacaagcct tgtgaattgg ttcaataacc taagtccgac aatgcaaaac gtggtagttg
    14281 tactcggaag tttacttgct gccattggac cggttgtcct tattataggg gttgttacta
    14341 ctcagatagc agctttccag caaggcgtcg gactagtctt taatgctgtc aaaggattac
    14401 aagctgcttt tgcctttttg acgagtccta tagggttagt catcgtagcc ataggtgcac
    14461 taattgccgt atttgtttat ttgtggaata caaacgaaca atttagaacg aagatcattg
    14521 agatttggac ggctatttcg aactttttac agcccatcat acaatttatt ggtaatttca
    14581 taagggaaac gtggactcaa ttagctactt tttggaacga aaatcaagca actattatga
    14641 caatagccca gacaacttgg tcatttatcc agacgatatt tacaacagca attgaaatga
    14701 taaaattggc cgttagtgtt tttttagggt tattgcaatc aacgtggtct gtaactttta
    14761 attctcttaa ggttatcgca caggtcgcat gggcttttat ttccaatgtt ttcaagggaa
    14821 gtttagggtc catacttgcg gttgcatctg ctatatttga gcaaattaaa tcaacgattg
    14881 atcttgcgat gaaaattatt caaaatatca tcaaaatcat actatccgcg atagaaggtg
    14941 attgggacgg tgtattagaa ggtatcaaag gaattgtttc cgcatttgga gattttattc
    15001 aatcaacttt ctcaaatatg atggatactg ctaaacgctt agtcggagct ggaatagata
    15061 ccgtaaaagg aattttcgat tctttgtgga atattgactt gttcggagcc ggtcaagcga
    15121 ttattaatgg attcttaaat ggtttgcggt ctatgtgggg agctgtcaca gatttcgttg
    15181 gcggtattgc aagctggatt gcagcaaaca aaggtcccat ctcatatgat agggtactat
    15241 tgaagccgca tggaaaagct attatggacg gactcggtaa tagcatgaaa actaacttta
    15301 aggacattca gaaagatgtt tctggcatgg ctgacgattt aacaagaagt tttcaaatca
    15361 aaaggttcaa cggttttttg ccagaaaagt atactactaa gcttgatgag cttaaaaaat
    15421 atgcgcaagc cacgcttggc ggaatgattt tagcccctaa catggcagtt caaccgacag
    15481 tcgttgttaa catcagcaat gaagcagata gcgatatcat caggcaaaaa gtcaatgcta
    15541 agaatgcaca agatgctatt attaatcagt tattcaagaa agggtaaaac atgttcagta
    15601 tagagttttt agacggagag cgactaagcg ccgatgaacg aggatggaaa gttaaagaga
    15661 tgtcctcatc aggacttgaa caaaacgtcg ttagcgagtc tcctaaaatg cgttctggtc
    15721 gccttgttta tggtctttat catggcatca aaacttatca acttgttttt acaaaaatca
    15781 ttaaagatac ccttgattat agccgtttag tagatgaagt taattactat tttttacgtg
    15841 atgaaccata ctatctttac cgcgacttta gaaagaaagc tgatcgggtg gacttgccga
    15901 agaagcgggc gaaggtgttt actaagtcaa tcgaccatca aaaaaatggg cttaaagttg
    15961 aatttacagc taagctggaa tcttatgaac taccctacga agaagatact gaggttcagc
    16021 gggtcacttg gacggcaaca cattcatggc acaataaggg agggcatcgc cttgaccctc
    16081 gttattgccc aatgaagatg accataacag tatcaggttc aggagctgaa cttaaggtgc
    16141 tatttaacgg tcagccttat ttttggtata aaaaatcagt taaacaaggg gatatcttta
    16201 tcattgatgg gacggacgtt gaaaaaaata gatacaattg ttttgaagat tgccataagc
    16261 aaacctcttt tttaaaaaca ggaaataaca gaatagatat tcaaggagct tcgtgtgaag
    16321 ctctttttga atatagacta ctgtatttgt aggagggtta gtatgcaggt aaaaacaaag
    16381 caaggtgttt tttatgttaa cgcagactac accgtcgtcg aaaaacaagg tgactatcct
    16441 aagctaactt gtactattcc tattaaggga aatgagactt ggatagcaga ttgccaagaa
    16501 cttgaccgct tatacccagc tggggaacaa gatgaattta ttattatcaa tcctattaaa
    16561 gtcactaagg ggagttcgta tgatttggaa attacagcga taggagcctt tcattttgaa
    16621 tttgtaaagg ctcgtctata tgaagaacta ccagaacgaa tgtatacttt agattacttg
    16681 ctcgatctcc tgtttaaaga cagccgattc agttataagc tacaaggtga ttattctact
    16741 agaaggttca gtggcttcgg agatgataac aaactgactt tattccatca tttaatggaa
    16801 cgatttcaaa cagaatttaa agttgttggc aaggtcgttt tagttaacac aaaagtaggt
    16861 aaagatacag gatttcagtt ccgctatctt agaaatatca aggatacaaa gtactcggta
    16921 gacgtaacta acctgatgac atacgttaaa ggatatggag cctggtttga tgaaaatgac
    16981 cattcaaagg gaagattaat tgttgattat gagagcccct tatccaaaga gtatggcaaa
    17041 cttgatggta agcccgttgt tgatgaacga atgagtttaa aagaaagtct tatcaaaaaa
    17101 tgtaagctag ccgtagatcg ctctgtatct gtcagcttaa caacgacttt agtctcttta
    17161 aaacaacagg attatcaagg tgcggcgaga ataggagact ctatttggtt tattgacgaa
    17221 cgtatatcta ttgaaaaaaa gattcggttc agcgtagtaa caacttacta caatgcatat
    17281 gatgatattt taaagcagga cgttacttta ggtgataaag atacctactc tcgatatcaa
    17341 agtttagaaa actcttctca aacagagaca aatgattttc aaaaagcgat gagtagcaaa
    17401 cttgcagaag ttcaagatga tgttaaaaag acgcatattt tagtatctgg cactactagg
    17461 attttctttt ctacagagtt tcctcaggat aatcctaagg gaactataaa agaagatgac
    17521 attttgtacc gtaatcacga tgggacaaca ttgatgtaca ggtggaatgg tgttcaatgg
    17581 gaattagtcc cgttggtaaa cgatccagat cgttggcgtg aggaactgga gaaacaaatc
    17641 tctgaggctg tcgaaaagct caaacaagag caaaaagtaa tcaaccagag aaccgataaa
    17701 gagctcgaag agtttagaga tacgctcaaa aacctatctt taccagagga agccattaaa
    17761 aaaatcacag aggctatcaa agttgatgat atcccgtcga ttaaacagtc atttgatgac
    17821 ttaaaaaata aagtcagcga gacaagcgag accgcacgat taaacgctga gattatcggg
    17881 acagatggca agacccgcta caacaaaaat ttgctagtcg gcgaccc
//
LOCUS       DARYJX010000045        17646 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYJX010000045 DARYJX010000000
VERSION     DARYJX010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17646
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(36..3146)
                     /locus_tag="TU257_001673"
     CDS             complement(36..3146)
                     /locus_tag="TU257_001673"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL0834668.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            3388..3759
                     /locus_tag="TU257_001674"
     CDS             3388..3759
                     /locus_tag="TU257_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0834669.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3759..4457
                     /locus_tag="TU257_001675"
     CDS             3759..4457
                     /locus_tag="TU257_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834670.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            4467..5261
                     /locus_tag="TU257_001676"
     CDS             4467..5261
                     /locus_tag="TU257_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834671.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(5308..5919)
                     /locus_tag="TU257_001677"
     CDS             complement(5308..5919)
                     /locus_tag="TU257_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0834672.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            6010..6358
                     /gene="ssrA"
                     /locus_tag="TU257_001678"
     tmRNA           6010..6358
                     /gene="ssrA"
                     /locus_tag="TU257_001678"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            6841..7197
                     /locus_tag="TU257_001679"
     CDS             6841..7197
                     /locus_tag="TU257_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834673.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            7721..8770
                     /locus_tag="TU257_001680"
     CDS             7721..8770
                     /locus_tag="TU257_001680"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0834674.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            9101..9343
                     /locus_tag="TU257_001681"
     CDS             9101..9343
                     /locus_tag="TU257_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834675.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(9465..10679)
                     /gene="thiI"
                     /locus_tag="TU257_001682"
     CDS             complement(9465..10679)
                     /gene="thiI"
                     /locus_tag="TU257_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL0834676.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(10681..11823)
                     /locus_tag="TU257_001683"
     CDS             complement(10681..11823)
                     /locus_tag="TU257_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0834677.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKSAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            12063..12503
                     /locus_tag="TU257_001684"
     CDS             12063..12503
                     /locus_tag="TU257_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834678.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(12573..13925)
                     /gene="gorA"
                     /locus_tag="TU257_001685"
     CDS             complement(12573..13925)
                     /gene="gorA"
                     /locus_tag="TU257_001685"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL0834679.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(14119..14460)
                     /locus_tag="TU257_001686"
     CDS             complement(14119..14460)
                     /locus_tag="TU257_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL0834680.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(14521..15687)
                     /gene="aroC"
                     /locus_tag="TU257_001687"
     CDS             complement(14521..15687)
                     /gene="aroC"
                     /locus_tag="TU257_001687"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL0834681.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(15800..16480)
                     /locus_tag="TU257_001688"
     CDS             complement(15800..16480)
                     /locus_tag="TU257_001688"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL0834682.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(16477..17640)
                     /locus_tag="TU257_001689"
     CDS             complement(16477..17640)
                     /locus_tag="TU257_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL0834683.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         5378 a         3959 c         3188 g         5121 t
ORIGIN      
        1 attcgtttgc aaattacttc actaattcgc tatttttatc gaaaaaccgt tttcaacacg
       61 taggggctaa tagcctcctc caaatcctta ctaacatcaa ccctaatatg gtttaactct
      121 aaggtttctt tgccttcttg ataatggata ataacaggag tctcccctga aaaggctgtt
      181 aatatgtcag aaatagcagc atcatgctga tggttttcaa ccaatagcca atacctttga
      241 ctctgagcta atcgaagctg gtgacagact agctgcaagc ggttatctct ttcttttacc
      301 ctgccattga tatagtaaat atgcccctct tttaggtctt gcttatagac agcatattgc
      361 tcaggaaaaa gggtaacatc taatttctgt ttggtatcag taacactcaa aaaggccatc
      421 tgctgtccgc ttgattttgt ccgaataacc ctgatcgcat ctatttgaac cagcaaagta
      481 gcttctgtat ccttcactaa ctttgtgatt ggtgtgactg ctactgtgct tttttcagcg
      541 acagctagca aggggtgctt gctcatgcca acaccaagca aatcctgctc aaagtaatat
      601 ttctcagcag ctgaataatc ctcagtctct acccagctaa aggaggaatc cgcaaaaagt
      661 gatcccaatt cattgacaaa ggttagcagt ccttctaagt tgttaatgat tttttggcga
      721 tttttttcaa acccatcaaa caggcctatt ttgataaggg gctctaagaa gctggttttc
      781 tggtattttt caggaatgct gcacaaaaag ctttcaacac tggtaaaggg cctattttca
      841 atgatccaat acgaaaattc tctaggaaga cccttgatgt tttttaagcc catataaatc
      901 ttatgacgct caatcttatc attgaaggga atggtgttta tcgtcacctg cgcggcctca
      961 aagccaaaat ctaacgcatc tgtgatgtaa tcactgctag aataattcat catgacatca
     1021 aaaaatacct caggatagtg cgctttaaaa taggctagct gaaaggctag ggcagcataa
     1081 gcaaaggcat ggctgcggtt aaagccgtag cctgcaaatt tttccatacg tgcaaacaat
     1141 agtctggctg tctcctcaga gcgacccaag gctctagcac cagtcagaaa atcctcctgc
     1201 attctttgca tctcaacgag gtttttctta gacatagcac gccgtagcaa atcggccttt
     1261 ccaagtgtaa agcctgcata aacttgagca atctgcataa cctgctcctg ataaagcatg
     1321 ataccatagg ttggctctaa tatcggagca atcaccggat ctattagatc aatgttttcc
     1381 tgtccctgcc ggcgcttaat aaaattctgc gtgtaatcac ttgctcccgg tctatttaag
     1441 ctggttgtcg caacaatttc ctcaaagcta gtcggcttga tccgttttaa caggctaatc
     1501 gcaccatgct gttcaaattg aaaaatgccc ttggtatcac ccctagcaaa caaggctatc
     1561 gtttcaggat cctctaggtt aatagcttca atgtcaattg aaagaccgta atcgttgacc
     1621 accttttcct gcattttctg tacaagcgtc aaatttctca gaccaagaaa atccattttc
     1681 agcaagccat tagcttcaac agcactggca tcatactgag tcaccatcat atcctccccc
     1741 ttttttaagg gaatatggtt ggtcagatgg tcatcactca tcacgatacc agcagcgtga
     1801 atagaggtct gtcttggatt gccttcaatg cgcttagcta tctcaaatgc cttttgaaac
     1861 tctaagcggc tattaatggt ctgtctgaag gctatatttt tctcataaac agtgctcagg
     1921 gtatccttga acccaatttt tttagttagg cttgttagct cgtattctgg gacaccaaag
     1981 cgtttgaaca catcacgaac agcctgctta ggaccaaaag tcgaaaaggt aacaatctga
     2041 gctgagtgct cactaccata ccggtctcga acataatgaa gaaactctga gcggtaaata
     2101 tcaggcaaat caatatcaat atcaggcatg ctgtagcgtt ctttattcaa aaagcgttca
     2161 aacaataaat tgtttttgac aggatcaatc ccagtaatgc gcaacgaata agccactaga
     2221 ctgcctgctg ctgaaccacg ccccatgccc atataatagc ctctactcct tccaaagcgc
     2281 agcaaatccc agacaatgag aaaataatca tcaaacccca tatctgaaat aatagccagc
     2341 tcctctgcca gacgaaattg gtaaggctcc ttccataatt gcttttctct tagaccagac
     2401 tcggtcaatt ctcttagctc ttcttttgct ggcttatcgc ggttaaatct cggaagcttt
     2461 aaatcagtat caaaatgata agcaatcgaa gctgttagat ttacgagatt caccaaagcc
     2521 tcagggcact tttcctggaa aatagccgtc atctcctgac aaggcgctaa aaactgatcc
     2581 ttggctacta gagccgtatc tgctaagcta atattatcac gaatggcatg cagcatttgc
     2641 agagtctcag tctcagcatt atcaaaataa cgtaccgttc taagcggaat cagtctttct
     2701 gtagagtcta tctttgacaa gtcgcttgcc tcatcaatgc caatgaagta atcaaaagga
     2761 agccctaaat cacgcaagct ctgactaaaa ggaacgataa ctgctatccc ttctaaatac
     2821 tgcaccaatg tgtctaggtc taggtctcca gacatttttt cagtcgaaag ctttaagagc
     2881 tgctgatagc ctgtatcatt tttcgcaaca agcttcagcg taagagcctg ctctttaact
     2941 gtaatagcca cctcaagacc taaaatcggc tgaagcccat gcctttgaca gcccttaata
     3001 aaatgatatg ccccatatag attatcctga tccataatcc ctatggcttg atagcctaat
     3061 cgtttggctt gtttaaaata atggtctaaa tcaatcaaac tatccataaa ggaataaact
     3121 gtttttgtat ctaactgagc aaacatggac atctccttta gcgttcttac taccattata
     3181 ctatgaaaaa gactttactg cccagatttt aagcttttaa tagcagtgat ctgtctttac
     3241 tgcaccacta tcagcaggaa tcccactagc attgcaagcc agtatgtaac tagagatgac
     3301 acacaaggct tgacaagtca atcgtttttt tgtatcattt aattagtaca aatattaatc
     3361 gcagatttta gaaagaaagg agacagtatg tcttggaaat ttgatgagaa atctcctatt
     3421 tacgcacaga tagcacagca tatcatgctg caaattgtca gccaagagat caaaagtgga
     3481 gatcagctgc cgactgtccg agaatatgct gaaattgccg gcgttaatcc caacaccatg
     3541 caaagagcac ttaccgaatt agatcgtgaa ggcatagttt actcgcaacg aactgccggc
     3601 cggtttgtaa cagataacca agagcttatc gcgcgcaaaa gacgagagct ggccatcaac
     3661 gagctcaagt cctttattag caatatgatc aaaataggtt ttgaacgttc agaaatcatt
     3721 cctgttttaa gtaccttttt agaggaggga tcaaactaat ggcacaacta ttacagctgc
     3781 accacgtctc aaaatcttac aaaaaacaat tagctattga tgatttaacc ataacaatcc
     3841 cttctggaaa aattatcggc ttactaggac caaatggtag cggcaaaact acactaatta
     3901 agctaatcaa cggactttta cagccagaca agggagacat tgttattgac ggctttagac
     3961 catctgtaga aactaaaaaa atcatttctt acttaccaga tacgacctat cttaatgaaa
     4021 gtatgaaaat caaggatatg ctagactttt ttggtgattt ctatgccgat tttgacagag
     4081 ataaagcgac cagtctcctg aaggatttag acttagatgc tgaagagcgc tttaaaaacc
     4141 tatcaaaggg aaataaggaa aaggcacagc ttatcctcgt gatgagccgc aaagcaaagc
     4201 tctatatcct tgatgagcct atcggagggg ttgacccggc agcaagagat tatattctta
     4261 aaaccattat taataattac tctgagcaag cctctgttat catttctact cacctcatct
     4321 cagacattga gcctgtactt gatgaagcta ttttcttaaa aaatggtaag ctctgccttt
     4381 ctggaaacgc tgatgattta cgagttcagc atcagcaatc gattgattca ttatttagag
     4441 agatctacaa ggtttaggag gtaggcatgt ttggaaaatt attaaaatac gaatttagat
     4501 caattggcaa gtggtatttt gcgcttaatg ccggtgtcat tgctatcgcg atagtccttt
     4561 cttttaccat caatacgctt acaaacaatc ctgacgaggt tggtttaaca acaagtctgg
     4621 caaacaaaat ggttcctctc acactctcat taacgtttgg ttctctgatt gccggatcat
     4681 tcttatcaac gctattaatc atcattaatc gctttaacaa aaatgtcttt gggcgcgagg
     4741 gatacttaac actgacacta ccagtaacag cacatcagat tatcttgtcc aagctgttag
     4801 cgtcctttgt ttgcagtatt tttaatggca ttaacctatt aatcggtatc tttattttaa
     4861 tagcgccaac agttgacttt acctatctac taaaggtgct aaagacaatt atgaagccag
     4921 aaaacttagt cgaaaatgct tctatcctca tctacatgct tttgtcaacc ataacaagta
     4981 tactattgat ttatctagca atctcaattg gtcagctatt ttcaaatcgt cgtggtttga
     5041 tggcattttg tgcctatttc attttagtta ttatcattat tgtcgtcatg acttatttaa
     5101 atgatgcgtt tttcaccgtc aacccaaata gctcagactc gctactctat ttcggtgatc
     5161 atacagccat atctatttta aacatagagc aactagttga aggcattatc ctttacgttg
     5221 ctactcactt catcatcaaa aacaagctta atatccaatg ataacaaaaa gtctagccac
     5281 tgcttatcag gcaatgccta gactttttta atggaaaaac cataggatca aatcctttcc
     5341 aaagataaaa agatagctgt agccaataat tgatagtggc ttcgtgatta aaataatggt
     5401 cacaaaacgc ttcaacgaca tctctgtcag cccagtaatc atgaccataa tatctgctgg
     5461 tgaaatcgga gaaagcatac agagaataaa caatctctca taatatggca tctctaattt
     5521 tctctcatac ttgtaaaagg tctgttcctc tataaacagt aaaataaagc gcctaccata
     5581 ggtcttcaca agtaaaaaca gaatcacact accaatgaag ataccaacat agttataaag
     5641 aaaacccagc aaagggccaa aaatcaaaaa gcctgcaata gttgtcatac cacctggaat
     5701 aataggaaaa acaatctgaa caatttgcac accgacaaaa acaagggggc caaaaacctt
     5761 gtgactatga acaagatcct tgagtgcatt gctgtcattt aaaatgccaa gcctgtaaaa
     5821 ccaaaaggct agcaaaaaag atccgactaa agccagactt cctaatagct taatcacttt
     5881 ttgccatatc acataaggct tcaactcatt atttctcata gcttcatcat accataagcg
     5941 ctattttttt gccattttaa aaaaattttg ctatactagc atccgtaagt atctcatacg
     6001 cctttttatg gggttgttac ggattcgaca ggcattatga ggcctatttt gcaactcatc
     6061 ggcagatgta aaaatgccag ttaaatataa ctgcaaaaaa taacacaact tacgctttag
     6121 ctgcctaaaa accagccggc gtgacttcta taggattgct tgtgtcttat tagaggtctc
     6181 aaaacagcaa gctacgttta ggtgattgtc tagtcaccta aaaagagaac cctagactcg
     6241 caggctgatg gcttgagtta tgtgtccttg gtctgttaaa gtaagacata acctatggtt
     6301 gtagacaaat aggttagcag gtgtttggac gtgggttcga ctcccaccag ctccatcaat
     6361 acttaccgta agttaccata acttactaaa accttgttaa atcaaggttt tttctttttg
     6421 tcctgttcgt gggttaccgt aagtttctat gaaagtgata gcaaaaaaaa ggccaaaaaa
     6481 tcctttaaga acagcttgaa ttttctcttt agctaatctt atatttattt ttttataata
     6541 cttcttctac ttgcttcatt gacagcacat tatcaaattt tttcggataa ttgccctgta
     6601 ttgcctgtta tatagacatc atttactgct gctttataga tatcatctgt tatgatattg
     6661 tgcttcttta caaaatttca ataatttaat tattccaaaa gctacattta tttaattttt
     6721 taaaaacact ttattaattt aattacaaaa acatttgact tttgacagat tttgagttaa
     6781 actaacattg tgataaggaa aatatcacaa aaataacgac ggacaaagga accgttggaa
     6841 atggaggaca cttatatgac acaagcttgt aagaaattta tggtttctac aatggctgcc
     6901 ctagctttgg caggagtctg cctaacagct tcaacccaca tcagcaaagc tgatgactat
     6961 gtttatggtg acgtggaata tcttttgacg cctaagcaag aaggatacga tgatttggtg
     7021 tcattcttgg agagtctagg ccttaaccat tttgatgcca ctctttattc ggactctatg
     7081 gctgatcaag attacaaaaa gctactagct gactttaagg gtaaaactcg tagtgaagtt
     7141 atttctgcag ttctatctga attagctaaa ttttataacg actattcccc tttttaatga
     7201 aataacccaa taagttatca tagatcaaaa ctgctcagac aaccttccga gcggttttaa
     7261 cttgatagag ctatgcttct ctttgtcaat ctgcttagta accagaccat ctcctaaatc
     7321 gtccgcctag ctaatcaagt aataactgca ccattgtcct tactatccta gctaatgccc
     7381 tgatttgctg actaagcttg gctaagattg tgcaagaatc ccaataacat caaagcctac
     7441 actagctctt attagtggtc tcaataataa cagctcatgt ctaaggcatg acaccaacaa
     7501 taccaaacgg tatcatcatt ggtaaaatag gtaacgctaa cataaaccaa gctgaaatat
     7561 ccattataga gatccagtct gccagcatct ctactatctc atcactattt actaataaat
     7621 aaagcttatc aaaagcattg tctcaacaaa atattgtgat aatatataaa tgtcattaac
     7681 attatttaat gataatatca ccataacaag aaagggttat atgaaaacaa tagcttatcc
     7741 aaataaacct cactccttat cagctggtct cttaactgct atagctattt ttagcctggc
     7801 gagttcaaac attacttatg ctgacgatta ccaaaggaat gctacggaag cttatgccaa
     7861 agaagtacca catcagatca cttctgtatg gaccaaaggt gttacaccac taacacccga
     7921 gcagtttcga tataataacg aagatgtgat ccatgcgcca tatcttgctc atcaaggctg
     7981 gtacgatatc accaaggcct tcgatgggaa ggataatctc ttgtgtggcg cagcaacggc
     8041 aggtaatatg ctgcattggt ggtttgatca aaataaaaca gagattgaag cctatttaag
     8101 taaacaccct gaaaagcaaa aaatcatttt taacaaccaa gagctatttg atttgaaagc
     8161 tgctatcgat accaaggaca gtcaaaccaa tagtcagctt tttaattatt ttagagataa
     8221 agcctttcca aatctatcag cacgtcaact cggggttatg cctgatcttg ttctagacat
     8281 gtttatcaat ggttactact taaatgtgtt taaaacacag tctactgatg tcaatcgacc
     8341 ttatcaggac aaggacaaac gaggtggtat tttcgatgct gttttcacca gaggagatca
     8401 gacaacgctc ttgacagctc gtcatgattt aaaaaataaa ggactaaatg acatcagcac
     8461 cattatcaag caagaactga ctgaaggaag agcccttgct ttatcacata cctacgccaa
     8521 tgttagcatt agccatgtga ttaacttgtg gggagctgat tttaatgctg aaggaaacct
     8581 tgaggccatc tatgtcacag actcagatgc taatgcgtct attggtatga aaaaatattt
     8641 tgtcggcatt aatgctcata gacatgtcgc catttctgcc aagaaaatag aaggagaaaa
     8701 cattggcgct caagtattag gcttatttac gctttccagt ggcaaggaca tatggcagaa
     8761 actgagctaa ccagtcatca ttaggaacag accaagtgct tattggtctg ttttttcgtc
     8821 taacaatagc cctattagct cactgtcatt ggttaaagct tgtcatgaac tctttaagct
     8881 cttgttttgt taaacattaa tgtgcctgtt gttcttttct aagataagta aactagatac
     8941 ctgacataaa aaacaaacgt tattatttat cttaataaaa aaatcatttt ttgaacataa
     9001 aatacgaata ttatactaaa aataaatcca aatagtttac aatttatggt tgttttcata
     9061 taattttcat gaaaggaggg aaatatatga aaaatctata ttgataagtt gtacactatt
     9121 agccagtctc ttattaactg gctgtcactc attgtctttg cagctagctg aggctgttca
     9181 ggaaaagcct attcaagcgg ttacggtaga ggatttgacc agacatggca ttgccgaatc
     9241 cttgaaagcc tacctacaga cgatgggctt aaccaatgaa gaggctatga aacaatacga
     9301 ggaggtcctt tctgatgaga ttatccagta ttttagcagc taaataagag aatttgagca
     9361 aaatcagcta aaaacaaaag ccagagcctt taataactaa taggtctggc tttttttgac
     9421 tgtttagata gactgcttat gttgtagggc taggtgcgca cctcctacaa caattcctca
     9481 ataagcgttg ataagctgtc agtttcgatt tcaggagtga tctcagttac tctgatccct
     9541 gccactgctc gctcgaccaa tccgtcgaca tcaaagcgag actcatatcg ttcaacattt
     9601 gctagcttgg gattggtttt gggacgatca ggagcaaaaa tagtacagca gtcttcaaag
     9661 ggctgaatgg aaatatcaaa ggtgtcaatt tgctgagcga tatcaatgat ttctagctta
     9721 tccattgcca caactggtct gataatcgga gttgaagtga ctgcattaat agcctgcatg
     9781 ctctctaagg tctggcttgc aacctgtcct aagctttcac cgttaataat cactaaagcc
     9841 tttcgcttct cacgaatagc atctgtgatc cgcagcatga agcgtctagt aagtgtcatc
     9901 aaataggctt cgggtgcctt atgcttgatc tcctcttgaa tctcggtaaa tggaacctcg
     9961 ataaactgta tattacctcc aaaacgtgtt aagcgctgcg ttagatcctt ggcttttctt
    10021 agcgcaccag gactggtata gggtgggctt gcaaaatgca ctgcctcaat ctcaacacct
    10081 cgtttcaggg atagatagcc cgcaaccggt gaatcaatac cacctgatag catcagcatt
    10141 ccctttcctg aagctccaac cggcagccct ccagctccct ttatatcttc gtgagacaga
    10201 taagcagcct catcacgaat ttcgaccttt agggtaacat caggattttt catctgtgcc
    10261 ttgatatgcg gcaaagcctc aaagacggct gctcctaagg tgtggttgag gtcgcggcta
    10321 tctagctcaa actgatggtc actacgcttg ctggatattt taaaggttag cccttcgcga
    10381 tacaaggagc tcataatctc ctgaactgct gctatcagta cagggacact tttttcaact
    10441 ttatagacag gagataagcc ctgaatacca aacaccggct ttaaggcttc aatcacagac
    10501 ctatcatctg caccattaag taaaacatgg gtcctgtctc gagttgatct gactgtcacc
    10561 tcagaatagg cagaaagaac atcttgaata ttagctttta gccgattaat aaaccgcata
    10621 cggttttttc ccttggtcga taactcccca tgacgaacca ttatttctga atatttcata
    10681 ttatctaacc ttttgtgttt tttcataaat ctgtttaaaa atcgttaaaa attgctcaac
    10741 ctgtcccata tcattatcat catctaggct gatacggact gctgtttgag ccaatgctgc
    10801 tggaattccc attgagacta aggttcctgc cgactttcca acctttgatg agcaggcact
    10861 cgttgttgat atataaatct catgcttttc aaatgcgtgc acaataacct ctccacgaac
    10921 gccctttata ccaaaggtca gaatatgagg agcaaaatca tctatctcag aaaagagaat
    10981 ggtatcctca taggcctgca aggcttgata aataaccttt ttcatggctg ctatccttgc
    11041 ttgagatcta tcctgtcttt ctgtgatgat ccttaaagcc ttggccatac ttgcaatagc
    11101 tgccacgttt tcagttgtcg aacgtagctc atcttcttga ccgccaccga ccaataaggg
    11161 agtgattcgc tttcctgatt ttttataaag aaagccaaca ccacgaacag catgaaattt
    11221 atgaccagaa aaagaagcta agtcaacacg cgcggttaag taagcctcaa caggaagctt
    11281 cccaatagcc tgaacagcat cgacatgaaa ggtaatggtg ggcttatcag ccaaaagctc
    11341 tgatatggct gcaatcggct gaattgaccc aatctcattg ttaaccgcca taatggaaac
    11401 taatatggta tcttttcgga ttaaggcagc tagctttttg acatcaacaa ctcccttatc
    11461 tgtgacagga gcataagaca gctcaaagcc ttgactttct agccatttgg cgctttctct
    11521 gacagctggg tgctcaatgg ctgagacaat gatgtgctta ccaaagtgag atttttcaaa
    11581 ggcaatcccc ttgatagccc aattgtcgct ttccgttccg ccagaggtaa agaaaatctc
    11641 tttggcctct acatcaagta aggccgctat ttgcctgcgc gaagcctcca atatacgact
    11701 ggcattggct cctagctgat ggagactaga gggattgccg taaatcttac tggccacttc
    11761 ctgatacgtt ttaagtgcct cttcgtaagg cttggtagtg gctgcattat caaaataaat
    11821 catgtgtcac cttcattttt attcaatact ttattgtatc acaaatttga tgaaatgaaa
    11881 aaatagatct ttttgcagga taggacaact ctatcctaga caataaggta aaccgttgac
    11941 ttgatttttg ttctagatta tactggtaga tgatagagct aagtctgaaa tgcctgttag
    12001 ccattaaaga cctaaagcat ttgactttag ctagcctatg actcgttaaa ggagatattc
    12061 tcatgtcatc acattattca cgtcaacaaa agcctaaaaa atcagcaagt attcccacaa
    12121 agcatattaa aactggcttt accgcccttc aaaaaaccat tgccttagtt ggtagtgttc
    12181 tgagtattgt tgtagcgaca atcactatta atcgagctct acaaccatca aatgagcaac
    12241 ccaaaagcga ttcctctccg tcatcaacat caacgattgt gaaaattatt gaaaaggagt
    12301 cgtcacactc aaataaggaa gagactgaca agacagaaac taattctgat tctagcggta
    12361 ctcaggcgac acatactact cctagctcag ctgatcctgc tactaaggat acagaaaaac
    12421 aacagaatac cgaaacggaa gcaccggctg ctaatcaacc cacagctaat gagccagctc
    12481 ctaacagtac aagcaatcca taacacaaaa cacgataaca ggcaattcag ataagctctg
    12541 aattgtctgc tatcgtgttt tatcatgtgc tgttatctca tggtaacaaa ctcttcagca
    12601 cctgtagggt gaatggcaac agtattgtca aaatcagcct tagtagcccc cattttaatg
    12661 gcaacagcaa agccttgaat catctcatca acaccataac caataccatg cagaccaacg
    12721 atggtctctt cttctcctgc aacgatcaat ttcattaggc agggctggcg atgactagta
    12781 atagctgtat acatggacgt aaattgtgat tgatagacac gaacagccgc ttgcccatag
    12841 gcttgaatag ctgcctcttc tgttaagccg atcgagccaa ttggcggatg gctaaagaca
    12901 actgtcgcaa ccttgttata atcaagcttt tcattgggct tattatgaaa caagcgctct
    12961 gccaagcgac gacctgctgc gacagcgact ggggtcaaag caagctttcc attaacatca
    13021 ccaacagcat agatgccatc aacagatgtg ttttcataag cgtcaacagc aatatagccc
    13081 ttcttatcca gctcaactcc tgtatgctcc aagccaaagc ctgtcacatt tggcttgcgg
    13141 ccaattgccc aaatcacttg gtccacttca agcctacgac catcggacaa atgcacttga
    13201 agagagccat cattagcctt ggtaacctta gtaacatcgg cattggtatg cagccttggt
    13261 ccagatacct tcatctcatc gaccagaacc tggataatat cctgatcaaa ggtcctcagt
    13321 ggcctgtcat agcgaaccag caaatccgtc tgagaaccta gggcattgag cactcctgca
    13381 atctcaacag caatatagcc agcaccgaca actgctgttc gttttggaat atcatctaaa
    13441 gcaaagaaac catctgagct aatccccagc tcagctcctt caatgtcagg aaaaataggc
    13501 tgaccaccag tagcgattaa aatatggggg gctgtatagg tcttacctgc aatgtcaacc
    13561 gtatgctgat caataaatcg tgcataatca taaatacgat caaccccgtt atgctcaaag
    13621 cccttctcat aagaggcatg aatacgatca atataggcct gacgattgct ttttaaggtt
    13681 ttaaaatcaa acctatcctc taacaccgta aacccgtaat ccttcgcata ggtatgaatc
    13741 gtttctgcta cctgtgcgcc ataccacatg acctttttag gcacgcagcc caaattaaca
    13801 caggtccctc caatagcctt gccctcagct aataggacct tagcaccgta cattgctgca
    13861 cgattcgccg aggcaatccc agcgctccca ccaccaatca caatataatc atactgaatt
    13921 gccattaatt taccaccttt actcttaatg cttgcctcaa tagatttgtt attaagctat
    13981 cattattgct ttattttaat ctactgtcat ttgactataa cataaaataa cttgtgtctc
    14041 aaatccctgc tacgacaaaa aaagattgtg ataagcatca acaatccttt cttctcttaa
    14101 tcctaagcca gcttagctct acttggccaa atccttcaat ggtgcaaata caatccgttc
    14161 aatatcatta acatagacgg aaagagcctg ctgagcgtta aaataccctt ttaataggtc
    14221 attggcctca attttttggc tgagagcctg aatatctgcc tgctctgtct ctgttggcag
    14281 ctgaccggtc tgcatgagtc cttgcaattt ttcttgcaca gcaacaaact catcaaatag
    14341 ctgactggca gcctcatctg ccttaatctc ttctctggct tccaaggcct tgcgatactc
    14401 tgggagcgca cgaacagctc gctcaagctt attggcataa tcataaatat cttgggacat
    14461 ctggatctcc ttttatcatt tattatcctt atcatatcac aatatcaagc catttgtcgc
    14521 ttaaaaatga tgaacatagt cacgataggc aaaaaaagcc tgctttaaat cggtcatatt
    14581 gtctgatgga aattgttcca aaatctcttt tgtgatgaca gttgctacaa cattttccat
    14641 cacgacaccg gcagccggca gagccgtagg atcagaacgc tcaacagtag ccttgtaagg
    14701 ctcgtgcgtc tcagtatcca cagacattag gggcttgtag agggtgggaa tcggcttcat
    14761 cacccctttg acaacaatag gctgaccagt agtcatacct gcctcaaagc cacctagtcg
    14821 gtttgttcga cgactgtagc cgcttgtctc atgccaaatg atgtcgtcca tgacctgcga
    14881 gcctttttgg tagcccatgt caaagcccat accaaattcg acccctttaa aggcgttgat
    14941 agacaggaca gcctgcgcga ttttggcgtc taatttacga tcccactgaa catatgaacc
    15001 taagcctgct ggtaagccat gaatgagtgt ttcaataata ccaccaagcg tatctccttc
    15061 ttttttgact tgatcaatat gggccttgat agtcgcctct tgcttgggat tgacaataga
    15121 taaatcagaa gactctgcta cttttttgat atctgcaaag gacatcgcct caggcacagc
    15181 tacctcgata ccaccaaaaa ctaggacatg attagcagtt tcgatcccaa gctcagtaag
    15241 gattgcctta gcaattgcac caacggccac acgcatcgct gtttctctgg cagaggagcg
    15301 ctcaagcgca tttcttaaat catcaaaacg atatttgatc cccccaacca agtcagcatg
    15361 accagggcgt ggacgagtga ttttacgctt gaacttgatt tgctcttcaa cagcctcaac
    15421 agccataatg tctagccatt tttgatggtc cttgttttga atggttaaag taattggtgc
    15481 tcctgttgtt ttgccatgac gaacacctga agagatatgc acacgatctg attcaatgcg
    15541 catgcgtgcg ccacgaccat atcccccctg ccgacgcttc agttccttgt taataagctc
    15601 agctgataat gctaagcctg caggaattcc ctctataatg gccgtcaaag cttgtccatg
    15661 tgactcacct gctgttaaat acctcattat tcctccattt atcaatcata gacataaaaa
    15721 gcaaacctgc cctcctctag acaactaaaa gacattattc taagctatcc aagagaataa
    15781 tgtctgttac cgtatcttat caatcctcag attccaaaac atgaagaatc cttttcatat
    15841 cagccaagga aacctgccct ggtgcactgg cttgatctaa ggacacaaaa gtccacgagg
    15901 accctacaac atcacctgcc aagcgtgata gtctgcctag ctttcccatt gacatggttg
    15961 caaattcctg ctctgggtta agtgttttaa agcctctggt ataattcatc aaatccaaaa
    16021 cgtcctgctc gctctgtggc atgacagcaa tcttgacaac gcgaggagct agcttagtca
    16081 tctccgaaaa agcctccatc agattttcag gcgtctcatc aaaattgtga taagacaaga
    16141 caagattcgg aaagtcaagc atttcatgaa agacagcctt gtgactaaag tattcaaagt
    16201 caatatagtc aggattataa atcgcattga tctccttgat caaatcaacg tattcctgat
    16261 cagaaagtgt aatatgccct ccttcttgac ttgtacgaag ggtaaaaata atctctctac
    16321 ctgcaaattt ttcaaaaata gctggcgcta cagaaacaat atcctcctta ggaagaaagt
    16381 ctgctcgcca ctcgattaaa ttaacatctt gatatttaga aacgtcgata gattgagcct
    16441 cttcaacatt tcttggcatg actggtgcta caattttcat tctcgtaccc ttatagtaaa
    16501 tacctttaaa taattacttc tttcatctgc tttattgata gtaaaatcac ttggaagctg
    16561 ctcaagtgtc atctgagcta atggcctgcc tcccaatcct ttgataattt gctttttaaa
    16621 ctggttaaca gtcatattgg cagcatttgt tgaagcgata attgttccct tgggggccaa
    16681 taggtctaga gcctcagcga ttaattgatg gtaatcctta ctcactgaaa acgtctgctt
    16741 tttgtttctg gcaaagcttg gtggatcaat aataataaga tcaaaagaaa gttgctttcg
    16801 cttagcatac ttaaaatagt caaaaacgtc cataaccaca agctgatgac tggataggtc
    16861 caactgattt tgaacaaaat gagcctttga taactctctg gagcgctttg ccaaatcaac
    16921 agaggttgtc tcaactgcac cgcccattgc tgcagctaca gaaaaagctg ctgtatatga
    16981 gaacaggttt aaaacagtct ttccaagcgc caagccgtcc accagacctc gtctaacctc
    17041 atgctgatca agaaaaatcc ctgtcatcaa gccatcattt aaaaatacct gataggctac
    17101 gccattttct aaaatggtaa aggtatcagg agcaaacgcg ccatacaaat gagccgtctc
    17161 cttatctggt cccttaaagc gaatcttttc ataagctccc ctgacctcag gaaaaacctc
    17221 tcgaaaagcc tgaataataa gctccttttc ttgataaaca aagacattat accaagaaaa
    17281 taaagcaaag tccttataga ggtctatggt tagtcctcca aaatcatcac cgtcttggtt
    17341 aaaaagacgg taagcatttg tccattcaga cgcggcaaaa tgctctcttt tcttcttagc
    17401 tgtcttaaat aaggtcacaa aataagaaac cgacaatttc ttaacagacc ttcctagata
    17461 ccagcctact cccttatgtt gctttgaaag gtaagctgtg ccgatgagct gatgagatga
    17521 attcacaagc tgcactaact ggtagtccca aatggtgcca tcaaaatcct tttcatctag
    17581 taattgtatc cctgctgcta tcttgcgttc aacaagggga ttaatacaga ccttattcat
    17641 agtttc
//
LOCUS       DARYJX010000046        16701 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYJX010000046 DARYJX010000000
VERSION     DARYJX010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16701
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..902)
                     /locus_tag="TU257_001690"
     CDS             complement(<1..902)
                     /locus_tag="TU257_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL0834684.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..2391)
                     /locus_tag="TU257_001691"
     CDS             complement(895..2391)
                     /locus_tag="TU257_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL0834685.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLS
                     WISKNTSLKIEYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANE
                     ALSMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVV
                     LKHIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEAS
                     YDMVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRND
                     AEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRR
                     LQCGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNG
                     STQVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
     gene            complement(2375..2590)
                     /locus_tag="TU257_001692"
     CDS             complement(2375..2590)
                     /locus_tag="TU257_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834686.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            complement(2740..3399)
                     /locus_tag="TU257_001693"
     CDS             complement(2740..3399)
                     /locus_tag="TU257_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0834687.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            complement(3443..5353)
                     /locus_tag="TU257_001694"
                     /pseudo
     CDS             complement(3443..5353)
                     /locus_tag="TU257_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(5461..7226)
                     /locus_tag="TU257_001695"
                     /pseudo
     CDS             complement(5461..7226)
                     /locus_tag="TU257_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            complement(7736..14566)
                     /locus_tag="TU257_001696"
                     /pseudo
     CDS             complement(7736..14566)
                     /locus_tag="TU257_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(14738..16165)
                     /locus_tag="TU257_001697"
     CDS             complement(14738..16165)
                     /locus_tag="TU257_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0834688.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            complement(16184..16363)
                     /locus_tag="TU257_001698"
     CDS             complement(16184..16363)
                     /locus_tag="TU257_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL0834689.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            complement(16447..>16701)
                     /locus_tag="TU257_001699"
     CDS             complement(16447..>16701)
                     /locus_tag="TU257_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL0834690.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
BASE COUNT         4513 a         3677 c         2353 g         6158 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat tgttatattc aagtgtttga cttgttatat agttatcttt
     2041 aatcactttg tattcaattt ttagtgatgt attcttactt atccacgata aatttgcatt
     2101 taacagctct aaaatatcat cattggtttc ataacaagta atttttatgg cttcaatctt
     2161 atcagtatca ataattcttt gaataagagc tgccgtaagt attcctgaac ccgctcccgg
     2221 atcgagtata gaaatttctt ttgaaaatga tgataaatca aataatgatg ccatgaaaag
     2281 agctgtttct ttacttgtga aaaattgccc atttttcttg cgaatttctt ttggcatctg
     2341 tttaatatat ttatttgtag attcaattac ataatcaatt attttcatca tccaccaact
     2401 ccataatttc atttacacca cagttcaaac tatcacatat tctgacaatc acatcagtag
     2461 taatattctc actgttcttc attttataaa aagtactccg gctaacttct gctttttcca
     2521 ttagctcaga atttttcata tctaaatcta tcattttttt aaatagcttt ttataactta
     2581 ttttcgacac gattgtcctc ccatgcatat gattttgttt ttatcattat atcatattta
     2641 ttcacttttt tcactacaaa cttcctttta cacaaacaca cgacatttag atagacaaaa
     2701 aagagtcggt gcagtcctaa gaccacaccg accatatatt tatctctcag cttctttgct
     2761 tgcgtctctc ttttcttttg gtttttcctt atcttcagac tgatatttct tgatagctcc
     2821 aagaacagat tctttctttt cttcttgtcc tttcatttgt tcctttgcct ttaagagctt
     2881 tgaagaaagt atccttacat tgctatgctc cttgccatta tcatcaatgg aagttctgat
     2941 ttgtccaaag agctttacaa aatctccctg cttaaagtct tttggaatat cactcttttc
     3001 tccataagcg gagcaattat gataaacctt atttccctca tcatctttag atacaacaga
     3061 gaaatttgcc accttaaagg cttctccatt cttgttttct ctttcagcta catcaacctt
     3121 tcctacaata tttccaacga tattgataag attatctttc tcttcctgaa catagggcag
     3181 gtcttttatt tgcccctgtt ctcgtaaatc ttcaatcatg tagtcaaatt cctcatgcag
     3241 taaattcaga ctgtcattgt ccatataagc gtcatagagc ttgtccaaag cactttcatc
     3301 attgatacct ttctccacgc ttataatcgc ttttacaaag tccttgtggt tatcatttgc
     3361 catatcttct atttgatttc tcattgtttt gtaatccatg ttttttatct cctttcatag
     3421 taaaagggag gttaccctcc ccttatctta aaaattcctg ttcttttgta gtttgttttt
     3481 cttctgtttt actttcttcc tgataggctc ttatctgtcc taaaatagat ggcttatcct
     3541 ctgatttttg tgaactttct tctttgctat gaaaattatc ctccacatca tatgttgatt
     3601 caaaatagtc gctgtcctta aagtcattat cgtaacggtc agtaattccg tcattatcaa
     3661 ggtctttaga aagcggatca tagaagttac cttcgtcatc aatatcaagt cccgttgctg
     3721 ctttcaaatc ttctgaatcc acataaacca gatcttcaaa agaggatagc tcaatctcat
     3781 ttttcatatt tcttagagtt tcattctctc ctttgttctc atagtcaaag ctctcagttt
     3841 ttatagatat atcatcaata tactgtgtcc atatcttatc ctctaaatta agctcatatt
     3901 gaatgctgtg tctttcatcc ggcgtgttgg tataggcaat tcctatatgc tttaagtcag
     3961 gatatagagc atcaaactca tcgtagctat gattttcttc atattctctg ttacagaaat
     4021 caataattgc ccttttaaca tcttctacaa ggggattatc atttctcttt tcttccacat
     4081 cacccatatc aagtagctta tttagttcag ccaagcgaag caccttactc tttaattcat
     4141 cagctttttc aaacggcttt tttaattcct ctttggcatt ttcaagctgc tctttggtgc
     4201 ttatgagctt ttcttcaagc ctctttaatt tctcaggcat tttctcaaga gcgttatcaa
     4261 gtcttgtaat attaccgtca gcacttgtgc caagctctcc tgaatgcttt gcaacaccgt
     4321 ttaagctgaa attatgagaa ttagtaaaga agttataact tgcttccaag tccatatttc
     4381 tgtacttacc gattacctta ctttcattga ttttaacctt tgaaatagct tcaagcaatc
     4441 tttctcctgc taatttctta tcggtaatct ttgctcctgc gatagtaata gaagtaaact
     4501 tttcctctcc gtccgcttta ggctctacat cagatatatc tttcttgaca gcttctatga
     4561 gcttttcagt tcttgcgatt tcttcaggat agtttttcgc cactttatcc tctaatctgt
     4621 aacggttgga cttatagttt gcttcaagca ttttaagttt cgtaacctca ttatccaaat
     4681 ccatcttttc tttaatcttc ggatcacctg tggcaagggc tttaatttct gcatagttaa
     4741 gtgaactttc atccacatct tctgccactc tgacaggtgt tttacttgtc ataatctgag
     4801 aaatgaactt ctgcttattc tctattgtct gccacaaata cgcatcaaag gtgttctccg
     4861 taacataacg atagatattt acttccttgt tttcattgcc ctgtcttaca attctgcccg
     4921 cacgctgctc taaatcggca ggacgccaag gaacatccaa atcatgaagg gcaatcagtt
     4981 tgttttgtac attcgtgccg gctcccattt tctgagtaga accaagtaat atcctcacat
     5041 ctcctttacg cacctttgca aagagttcgt ccttttgttt atcggaattc gcttcgtgga
     5101 taaaggcgat ttcttctttt ggtattccca ttgctacaag tttttctcta atatcatcat
     5161 agatgttaaa ttctccatcg ccttttggtg tagacatatc agaaaatagt agctgtgttg
     5221 acttatcttc ttttgtctta tcccatatac taaagacatt tttcacacag acattgacct
     5281 tactgtcagg attgtcaggt agcagaggat taattaaacg ctgatctaag gcaagttttt
     5341 taccatcatt agtgtagggt aggatactag cgaggtagtc attgcgaccc cttttccatt
     5401 atccccccac cgaaccggac atgatacttt cgcatcatcc ggctctccag taatttcatt
     5461 tcataaacgt gtatttattg aaccattatg tattgcatgg tgacaatccc gacaagtcac
     5521 tagcattttt cgacgtcttg ctgacatgat ttctttccac tttggaacta atttcccatt
     5581 gtgtttgttc aagtctgcta attttctgat atgatgtacc tctatgttct cctcacttcc
     5641 acatagctca cacttatttg cgagtaatcg cttgataagc tctgttcgac caccataaac
     5701 ttgatacgga gcatcttcta ttacagcttt ctttttatgc caccccacgt tgcaactaga
     5761 ggaggtttat cttctcgaga cacaactacc tgtaaacacg gcaccgttcg gccattcgtg
     5821 ctagttgtgg tagtcttata tttagctaac attttattaa tggatgactc atgtttaaat
     5881 gctaatgttt taaggagtga tgtttccata taccaataga cttttgagaa ccatgacaaa
     5941 ttttgtgcca atatataata ttgaactagc cctctatatt cttgttggta agtttgaacg
     6001 atactaaagt catcatcatg caataagtta ttacgatgaa tagctttacc atttttcatg
     6061 tattggcggc atttgctttc aataactgat gcaggtacaa ataatgcgat aacaccattg
     6121 gcactctgtc tccctttgtt atcaatataa tcattgacac gttgtgcttt tatctcatat
     6181 cccagaaatt tagctgattc tccagtcgca tgggtaatca aagtcttttc ttgagaaagt
     6241 tccaaagata acttagtatt taaaaagtct ccaatttgct tctttatagc ctttgcctca
     6301 gcttttgaac ctgtaaagcc tagaataaag tcatccgcat accgaacata tcttaatctc
     6361 cgatagctgg tatcataagt atcaactgaa gggagatttc ttctctcaac aattaactga
     6421 tgagcttttt tataatctcc tttatcctga tagcatttaa ttcttctact caaacgatta
     6481 taggctgagt ttgctttctg ctttttacct cttgtatatt gaggtatcag ctcttcaccg
     6541 acccacttat caaattgatg taaatagata ttagctaata aaggactaat aactccacct
     6601 tgcggtgttc cactaatagt cttgtgaaac ttccaatcat caagatatcc tgcctcaagc
     6661 atatttttga taagcctaat aaaccgacca tcctgaattt gtctagacaa catagtgatt
     6721 aatacatcgt ggtcaatcgt gtcaaaataa ctagagatat ctccttctat gaaccaacgt
     6781 gtccctttcc aagtctgaat ttcttgtaaa gctgtatgac accctctttt tggtctaaaa
     6841 ccatgagaat gttcactaaa ttgtggctca taataggctt ctaatatcat gcgaatcact
     6901 tcctgaagaa gtttatcact ccatactggt attcccaaag gacggtgttt tccattcttt
     6961 ttaggaatgt actctctcct agctggtctc cagtaatagg tttcttgtct taattgttca
     7021 ataatcatat ctattttttg aatagacatt ccatcaatcg tttcctctgt aacacccttt
     7081 gtcattgctc cattattcgg gtataacttt gcataggcta tcagatagag ttcacgatta
     7141 aatagtaact tataaaccct ttcgagtggt ttatcttgtt ttccacgttc atgaatgacc
     7201 gttaaaatag ttttggctgt acgcatccca cgcacctaat cctttctaac taatcgaaat
     7261 tacctgtcac ccttcgccat gtacaaggat ttcccttgct cggactacta cggtgactcc
     7321 gttaccataa gggtcccccc tcttaggcaa tcctgctatt cgttaaaaat gtacgttcta
     7381 gtaaccctta ggttcctcac tcattccttt attcatactt atcgtatgct cttttactgt
     7441 agaaagttat tcgtccaaaa tcacaacaac gaatatacag taacatcggt ctcagttact
     7501 ttccgatggg cgatgctttg cacctagtca gaattgaggt tcaagcagtt tagccttaac
     7561 cataggttac ggaacttgcg gcacatcaaa gcgttgtaac tcactcctta tccgctttac
     7621 taacatgcta ttgtcccctt tgggtttccc cgctaggtta gttagttgtt cctattattt
     7681 actttcaata atatccctct gtgagggaga tacattttta cgcttaacag cgcacaattt
     7741 ttagcatatt atctttgtca ggctctacca ccctatttct cacatcatct gctctttcag
     7801 aaaggctctt tagaatttcc ttttgctcct cacttggcaa ggtcttaatt acttcataat
     7861 gtgcctcagg tgttggaaga tttaacatat ccgctgtttg aatgtcagcg acttccttaa
     7921 acatagacat tagttcaggc aagttataga acttggaaaa tcttgtcttt actctgtatc
     7981 ctgttccctc cggagaaagc tcaaaagcag actgcgtttc cccaaaagta gaagcccagc
     8041 tatcaaaatg ctccagatta tttttcttta agctctcata ctgaagataa cgctgcatag
     8101 tgtaaagctc agtcatggag tttgatacag gcgttcccgt tgcaaagaca atgccttttc
     8161 cgtttgtcat ttcatccata tagcgacact tcataaacat atcggaggac ttaaaggctt
     8221 cactttgacc gattcctgca acattacgca tttttgtata aagatagaga tttttgtagt
     8281 tgtgtgcttc atcaacaaag agcttatcaa ctcctaattc ctcaaaggta atgacatcat
     8341 ctttcttaaa atcgtcattt aatttctcaa gccttgtttc cagttttttc tttgtctttt
     8401 caagctgttt tactgtaaag ttctgatttc tgtcatgctt gtattcttct acatagttta
     8461 cgatttcatc aatctgatct tggatatgct tctcctgata ttccttagac ataggaattt
     8521 tttcaaactg cgtatgcccg ataacaacgg catcgtattc tcctgtggca attcgaccga
     8581 taaaacgctt acggttcttc ggctcaaaat ctttcttatc tgccaccatg atatttgccg
     8641 acggatatag ctgcataaac tcacgaccga tttgtcctgt taagtgattg ggtacaacaa
     8701 acaaggactt actacacatt ccaagtcttt tactttccat tgcggaagcc accatttcaa
     8761 aggtctttcc actgcccacc acatgagcaa gcagggtgtt gcctccataa agacttcttg
     8821 ctatggcatt tctctgatga ggtcttaaat ctattttagt attcattccc tcaaaggaaa
     8881 gattacttcc gtcatattct ctgtttcgga tagagttaaa acgctcatta tacagtttta
     8941 caagacggtt tcttctctcc tgatcattaa atatccagtt cttaaattct tcttttagta
     9001 gttcctgctt ttgccctgca agcatggttt cttttttatt tagtacagaa gttttagagc
     9061 cgtccggatt tacaatctgg tcaaatacct ttgtttcttt caggtttaag gcatcttcaa
     9121 tcagcttata ggcatttacc cttgatgtac cgtaagtcat ttcagcgagg tcatttcctc
     9181 tatccctact tttaccttct atattccact cacttgtcag gtttgaaaac ttaaccttaa
     9241 tatcccatct tgcatatccc ggagttttca gcgtttcaaa aataaatttt tcaatatctt
     9301 taatcggtat ccaagtcgca ccaagacgaa cacttatctc acttgcttca agctcctttg
     9361 gtagaacttt tgtaagctca gccttttggt attccaaacg attcatctca tagctaatca
     9421 gctctttttc tttaccatct tctgcatagc caagatgagg taactctctt tccgtctgtc
     9481 tgagctttga tagatagcta tctactatgg caatcttgtc cctgatattc ccacttaaat
     9541 attcatcctt tgttacatag ccgtatttgt aggaattact gccattggca caggcaaaag
     9601 gcaaatctcc atcttcgggg ttaaaggata gaggtctata aaagttttgt tcttccctaa
     9661 tatttaagta gatttcccct cgaagctcct caatcaaagt cggtctgtct tttcctgtaa
     9721 gaccttccat atagtcaaag tccacatatc ctttttcaga taccgataag acaagggctt
     9781 ctaaagaagt atccacatga tctatgactt tagcctttgt aatagttctt ttggagaaaa
     9841 tatctccctt tgccttaaag ttttcttcat caaggatttc aatggaggaa acaagcggga
     9901 agttgctatc ctcttttaaa gctcttgtat tgcttaaatt atttacaaag ccatgcttat
     9961 tagaaaaacg gtcatagact tcatttagtt tttcctgtga agccttgatt tcttcctcac
    10021 taaaaccttc tttctgcttg taaatcacat tttttaaggc agcattcagc tcaagataat
    10081 ccttgatttt ttctttgttt ttatcggtta cttccttttt gataaacagt gagttttctc
    10141 tgtaatagac ttcatcatca ataatggtat aggaaaagtt cttaacatca tccgttgcag
    10201 ggattgaagt gatttcatca tctaaaagct ctatttcttc atacttggca tcttttgaaa
    10261 ttctttctcc tgcaatctcg atacgatcct ttaatgaagc catatttagc tctgtgccta
    10321 aataagatat cggttcacaa gttagagttt ttccaaatct tccgcttact tcacgcattg
    10381 agccaagtac ctgttcagga tgatcaacaa agtatttgtt atatacaaga ccgttttcat
    10441 cttccgcaag gtgtatccaa tcttcatcac gctctaatac gctatctctt ttctttaaga
    10501 agataatatc tgaggttact tctgtgccgg cagtaccctt aaaggtgtca ttaggaagtc
    10561 tgatagctcc taaaaactct gctcttgctg caagatagcg tcttacactt tcatcctttt
    10621 tatccattgt tccacttgat gtaataaagg cgataacccc gccgtttcta accttatcaa
    10681 tggacttggc aaagaaatag tcatgaataa ggaagttatt acgattgtat tccctgtcat
    10741 ttactttgta ttctccaaag ggaacattgc cgattgcaac atcaaaaaag ttattggaaa
    10801 aagaagtttc ttcaagtcct ttaatctgta tatcactttc agggtataaa agttttccaa
    10861 tcctaccgct tatactgtca agctctacac cataaaactt tgacttgttc atttcatcag
    10921 gaagatttcc tataaagttt ccgatgccca ttgatggctc aaggatattt ccgctcttaa
    10981 atcccatatc ggaaagtgtc ttatatacgc cgtcaataac agttttcggt gtgtaaaagc
    11041 tcgttagggt agattctctt gcagcttcat attctgcctg agataagttt tcctttagaa
    11101 agctcctcgc ttctttccac tgtccgcctt tttcttcatc gaatacatca gcaagtccac
    11161 cccagcctac ataccttgct aaaacttcct gagctgtact gtcaaactct ctttgtccac
    11221 tttcgatgcg actcagcata gagatggctt caaggttatt atttagcctt tcacttggag
    11281 ataacttgtc aggtaatgtt tcttccgtaa tcttgaagtt atgagcttct gctttcttta
    11341 tttcactttc tttagcaata gtttcaggct ttttatatgt cagattttca aataccctct
    11401 caagatcgct ttcaagacga taaggaatta catctgagcc tgttatcata ccgccaagat
    11461 attcggtatt atccttaacc gttaccgtct ttagattatt tcccatatcg tcaaagcgtg
    11521 tgatggtata gtctttatcc ttgtatttaa tttcatctcc aacgataaac gcaggtcttt
    11581 cagggcttac ttgtcttaat aaatcttcat tatctgtaaa ggctacaata gggatttgat
    11641 ggtttccact tcttcccgga tcaagccata agtcatatct ttctgtgatt ttattttcag
    11701 caatttccct tacagtatat tcttcatgat taaaatagac ggtatcgccc tctttaactg
    11761 caaattcatc tgaaatactt ttcttttctt cgttaagctc tacttcttcc ttctccttca
    11821 gataatcaaa tagtgtttcc tgaacaggtg ttgcagctac tctttcttcc acttcttcag
    11881 atatttcaag ttcttcttta tcttcaaagc taagttctcc gttaaagact gattgaagtt
    11941 cctgttcatc catctgcttt gcaagttctg tatctttaag ctctctaaaa gtctttggaa
    12001 aatcctctaa aataagcctt tgagcattta attctttcaa ttcttcaaga ttgaaatatc
    12061 cccattcagg ttcaaatcct aacacaagtc caaaggcatc accgctttcc ctatcatatt
    12121 ccgtcatata ccaagtccag ttagaacgga aaggaataat atatgctgca tgaacctctt
    12181 tatccgctaa agctacatct tcctgtgcgt aaagctcagg cactctttca agcatttcat
    12241 cagtcattaa gttttcagga ttatctttag aataatattg tagctctttt gattcttcta
    12301 cctctgactt actttctatt ttcttttctt catacagatt tttagaaagc agctcctcta
    12361 tacgctttgc cacacttgac caagtaagaa aaacatcatt acaattattc ttctgtaatt
    12421 taagcccctt tgcatcatgc cattcatcac ttcccattgc ccccgatact gcatgacttc
    12481 taccacctat gccatattcg tcttttagga aattagcttt ttcctgcaag gtatgatttt
    12541 ctttgaaaaa ctttgtaatt cgctcttttc ctctatcgac gcctcttcct cttgaaagac
    12601 tttcaaggac ttcatcttct gtaatgaagg actttacctt cggaagctct gttagattgg
    12661 tactatattc ctttcgtgac agctcaagtt cctgtaacct ctgacaaagg ctatctacct
    12721 tgtgatagtg aaaccttaat acatttctgt tttctttgta tccttctaaa aacctgctgt
    12781 attctttgat cgtttccttt aggtagtcgg gattttttaa tgcttcagac aatctttttg
    12841 tttcttccgg aaagcctctt ccacttgttt tcaatagttc aaaatatcct tgtccttctt
    12901 cgcttaaatc atgcattaga taccataagg actctgaaat cttatctctt tcataatcag
    12961 gagcctcaga aatctctaca tttgtagcaa actcaccatt atcaagaagc tcatttatcc
    13021 tctttgcagc atcgctccag cttaaaattt gcgtagtatc ttctcttgca gatgtcccgt
    13081 aggctaaatg aatgccttta tccgaatacc aggaagatac ttctctttca tcaatgtaaa
    13141 atccattacc gcctctaaat atatctttta ggtattctcc taattcttca ttactttttc
    13201 ctttagaaaa ctcagcgata acaggaagtc tacttccatc gtgatttcct ccgttaataa
    13261 ggacagtatc tatatccctc tgagttaatg gaatggtaag tctcatctgt ccatatgaat
    13321 tttcgggtaa agaaaaagaa gccttttcag cttctcttat ctctacctca gtattatctt
    13381 ttaaattttt aatacttcct tgattgtcat ttccttcaga gctgaaatca tcgccccata
    13441 ctgcggatcg ttctcgtcct ctatcttcca agctaccatc aatttcggct tctctgtcct
    13501 cataaagtct atcgcctgtt tctgaatatc catcaggtgt cctgttagct tcctctcctt
    13561 gtatagatcc actaacatct cgaagtggct ctgctcctcg ctctctgaaa ggtaatccag
    13621 cctcattact gcgtaggtcg gattcggata ctcccttatg aagtccgtct gttcctccaa
    13681 gctgtttagt gtattctccc tgattttctc tattatctcg tccgtactct ccatttcgga
    13741 gaactcgctc attttcattt ctttcctgat catctcgtcg aagtacatca ttatctcctt
    13801 tctcaatttt ttctttaatc ctattatatc ctgcttcttt tcctcttaaa acttcttttt
    13861 gaagctcaag ctctttgctt ttttgaatgg tttcatcaat aatctttcca ctaatatccg
    13921 atacgatttc accaagactc ataagggaaa tgctatcaag cattgcaaag ttttccttta
    13981 gaagctcatt atccatagga tagtctacat taaatcttga agctactgca taactcactg
    14041 agtccctcac aaacttggta aaagatattc tatcctcatc agctattcta agctcattca
    14101 taaggctgtc tatcttttca tcaccgtaga gtctacttaa agaaaagata ttttctaagg
    14161 tgctttcact ttcctcatag ccctcgtttt ttatcatttc ctttaagaca tccctatgag
    14221 cttctttatc aaatctccaa agattgacct cattgacatc cctatttctt gaaaccgtct
    14281 gacttatatc aaagatatat gccacttttt tgtatgtgcc gtagtcctct aaaatgggga
    14341 tacctttttg tcctctcata acagtacggt taaagcgttc cctccaatag tcgaacttgg
    14401 cacaggctgt cgcttcagaa tttctatcat aaatacttaa ctgacttcta aagtcatatc
    14461 tttgattgtt tccgacaacc tttaggagct tcaggtattc tgcttcactt tgcaaaatat
    14521 tttgttttac aagctccaaa atgttatgaa aatcatttat tcgcattttt acctccttct
    14581 ttttccaaac aaaaaaggcg gttagatttt actctaatca ccttttgatt ctgtgtattg
    14641 caacttgctg caacttaaat ttcctactac aaatcctcat tttatggtat tcatagcacc
    14701 ctcttattta taaaaatctt tgttttgcaa cttaatttta ttcattcagt tcccagtgtc
    14761 cgctattacc acttcctaca tacttcagat tatctatttc ctttatagct ctttcgatag
    14821 tctttacgct aactccagct tcatctgcaa tagcctttct tgtaatccta tcattgcttc
    14881 tcactttttc tttaataaac tctgcgagag ctatcttatc gtgagcgaca tcgtgagcga
    14941 caccctgagc gacatcgtga gcgacattgt cgcctccaac cttttgtgtc gctatcttct
    15001 ttagaggaat aatcgttctg aatatatctc cctcctcaaa tagcgggttt tgtcctgaat
    15061 aaagctgtgt gtatttgtag gtatttcgca ttcctgaacc aagttcatcc gcaagaccta
    15121 tttctctaaa aactttagat atagcaggat ttttaggaaa tggctcaaac ttctgtaaat
    15181 ctaaagctcc catcccatga gccaagttgc tgttttcaac tgtaatcctc tcatcgtcaa
    15241 taatcatctt tgcaggaaaa ccacttgaat aatctctatg agccagcgta ttggaaacta
    15301 tttctctgag tatcctgtct cttgcattga cattgacaat tccgtccaag acaaataaat
    15361 cattcaagtg cttttgtcca aattctatca gtctgtcata gctgtcaatc agatttgtta
    15421 tgacaacatc tctatcatca tatctatcct tattttcaac cctgaatata gcatcagttt
    15481 tgtgttgcgg aagaacggac ataatagagt tatcttttcc aaataacaaa atagcagcta
    15541 atgtgattcc ttcacgcttt gtttccggat ctgtcagtat caaattggca cttctaagaa
    15601 gctcctcatt actcatattt tcccaaacat gatttttatt tcggaaaaca gccattttct
    15661 tagctttatc aatgacagaa gcatcaagaa aatcaatatc aagattcgga tataccttat
    15721 taacaaaata gcttccttgt tttcttgcat atagcttata tacaagctct gaatgatctg
    15781 tgatattgat gtccccttca taagacctat cccaaattct tccgttatgt ctgcatacct
    15841 gataaccttc aggaactctt atataaataa cttgtttccc ctcaatttca aaagtttccg
    15901 gcagcaaata aagtggtgga tacatctttt gcggattgtt gattgccgta gtaaattcct
    15961 taatcacttt atctacttta tcttcactaa caccaacgat ctctctttta tcatttgcac
    16021 caagtaaaat atgtccgcca tttctattgt tgaaagagca tactgtatca aagacatctt
    16081 tggttaaagc gttcttggat tctttaaatt cgacatctat tttttctccg gcttgaatta
    16141 acttcttaat ttcatctatc gtcatctgtt tatttcacca cctttatttc ttaatgtttt
    16201 cttcgataaa aacattggaa ttttgaattt caactctatc tttattaact acaaaagtaa
    16261 catagtctcc attttctaaa ttcaaaagtt ccctaatcct ctttggaata gtaacctgtc
    16321 cttttgacat aactttagca gtatctataa atgtatcttt catgactaat ccctttcgcc
    16381 ctacttttcc tacaaaagat tatagcactt ttaagatatt ttttctactc tgaaattagt
    16441 gtcatcttac ttactataag ttgaaaccgc ttcttttatc tcattttcaa tcgcttctaa
    16501 aaattcttcc tttgaagatt tcccttgagc aatatcggat aattccattt cccattttgc
    16561 ggtagtttct gccgacttaa agttatcagc tacaatcgct acaaggctta ttcctttatg
    16621 tgtggctata aggtttttct tatctctttc tacaaatccc ttaaagatta agttttcaat
    16681 aatccctgcc cttgtgaact g
//
LOCUS       DARYJX010000047        15637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYJX010000047 DARYJX010000000
VERSION     DARYJX010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15637
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1031)
                     /locus_tag="TU257_001700"
     CDS             complement(<1..1031)
                     /locus_tag="TU257_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834691.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1037..1891)
                     /locus_tag="TU257_001701"
     CDS             complement(1037..1891)
                     /locus_tag="TU257_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834692.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1958..2158)
                     /locus_tag="TU257_001702"
     CDS             complement(1958..2158)
                     /locus_tag="TU257_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0834693.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2531..3268)
                     /locus_tag="TU257_001703"
     CDS             complement(2531..3268)
                     /locus_tag="TU257_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834694.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4019..4324)
                     /locus_tag="TU257_001704"
     CDS             complement(4019..4324)
                     /locus_tag="TU257_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0834695.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4326..4664)
                     /locus_tag="TU257_001705"
     CDS             complement(4326..4664)
                     /locus_tag="TU257_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL0834696.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSPGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4692..5447)
                     /locus_tag="TU257_001706"
     CDS             complement(4692..5447)
                     /locus_tag="TU257_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL0834697.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5708..6163
                     /locus_tag="TU257_001707"
     CDS             5708..6163
                     /locus_tag="TU257_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL0834698.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6147..6797
                     /locus_tag="TU257_001708"
     CDS             6147..6797
                     /locus_tag="TU257_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL0834699.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6907..7811
                     /locus_tag="TU257_001709"
                     /pseudo
     CDS             6907..7811
                     /locus_tag="TU257_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8164..8439)
                     /locus_tag="TU257_001710"
     CDS             complement(8164..8439)
                     /locus_tag="TU257_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834700.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8862..10412)
                     /locus_tag="TU257_001711"
     CDS             complement(8862..10412)
                     /locus_tag="TU257_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0834701.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11083..11643)
                     /locus_tag="TU257_001712"
     CDS             complement(11083..11643)
                     /locus_tag="TU257_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0834702.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11621..12490)
                     /locus_tag="TU257_001713"
     CDS             complement(11621..12490)
                     /locus_tag="TU257_001713"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL0834703.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12582..13853
                     /locus_tag="TU257_001714"
     CDS             12582..13853
                     /locus_tag="TU257_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL0834704.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13889..14227)
                     /locus_tag="TU257_001715"
     CDS             complement(13889..14227)
                     /locus_tag="TU257_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834705.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14327..15415)
                     /locus_tag="TU257_001716"
     CDS             complement(14327..15415)
                     /locus_tag="TU257_001716"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL0834706.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4830 a         3442 c         2720 g         4645 t
ORIGIN      
        1 gccaatttta ataataattc ttgtgtacca aaggtttgta cggatacaaa tgttaacagt
       61 ttgttcatca aaccttctgg aaaaattccc attagaaaga ccggtgcata tacaataaga
      121 gcagatatac caaaagtggt tagaggagac ttagttagag atgaaactag tgcatgaatg
      181 cctgtcataa atatcaggcc aatatactga aacaccaata aatagacaaa cgcaatgcct
      241 aaggtcatct tttccgggaa agccataatg tttatcactg gatcaatcca atacaaattg
      301 agttgtaagc tagtgtccca gccgctaaaa ccaaaatagg tcgcaaagac agcaaagacc
      361 agaccactag caattgcaaa taccaaagta ctgacagcta tgctaactgc taatttagca
      421 agagtcaatt taccacgtcc aaaaacagtc gtcaataaga tagagttcat ctttttagat
      481 gattcccctg aaaataaagg agccgttata taaagacaaa gcataacaac aagaagataa
      541 gtactattgg ttacatcaaa caactgattc caaggagcaa aattacctaa cttcaactct
      601 ttcaaaggca gagcggaccc caactcttca cgtgatttga gatgaacatt gtcaaatgtc
      661 agagacttat cagtgctatt aatagcgata agcttatcag tagacttagg cactaaatga
      721 gagatagcat aatgtgatac cacactatat acacccttct tttttaggtc tgattgattt
      781 ttagcataat cattgaggat acgactaatc agatcgtcag ataaataacc tgtatgcttc
      841 tcagcaattt gttggttaat tgctacagct gcacgtccat gaacctgatc tgcagaagag
      901 ccactgatct gaccgttaaa aaaatgctgg taaaaaagac cacctacagc caataagacc
      961 actacaatcg caccaaatac cgactgtcgt cttaataatt ttttaaactc aaagggtatg
     1021 agagatgcca tagaattcac tcctttctaa aatgataaat gtagagatcc tctaatgttg
     1081 gtgacacagg atttgcctga taacaaggac tctcatcgct cacaacacgt aagatacgat
     1141 tattttttac aattttttca ttgacaacgg catagtcagt caaaaatgct ggtgcactct
     1201 ctgtagcaac aggaatctcc cataccttgc cgatcattgt ttgaactaac tgatcaacac
     1261 ttcctttttc tataaactga ccatgcttta gaaggattac ctcctttgca accgcttcta
     1321 catcagatac aatatgtgtt gataggataa taattttttg ctctgataaa tcactgataa
     1381 tatttctaaa ttttacacgt tcctttggat caagtccgac tgttggttca tctaaaatta
     1441 acagtaaagg atcgttgata agtgcctgag caatacccaa tcgctgcttc ataccgccag
     1501 aataagaagc aattttcttt tttctaacat cataaagacc taccagcttt aataaccgat
     1561 cagcttctac taaagccttt ttacgtttaa cattcttcaa agcagccata taaagaagga
     1621 attctaaacc ggaaaactgc tgataataat taaactgttg aggtaaaaag ccaatattct
     1681 ggtaaaagtt ttttggttgt tgttgatgat ttaaactaat ttctccacta tcaggaactg
     1741 taaactgact aatgatgttt aataaagtcg ttttaccggt cccatttgct cccaataacc
     1801 catacaagcc tggtgtaaat tgtgcagaaa tacgactcaa caccttttta cttccataag
     1861 atttagaaat attatctagt attaacaaca ttgtcattcc tcctaagtaa aaacccaggg
     1921 aacagcacca cttcgctgct ccccagatga ttaaccatta agcattatat actcgacaaa
     1981 cggtaccagg ataaagaatc atgtggttat cagcattttc ttgtgctgta tctcttaata
     2041 gatgccatgc acttgtataa ccatcagtgc atctccacct ataaccccaa ccaccttcaa
     2101 cgcctgcaag catatcagca gtcattgtac taaattgttc aattgttttt gtattcatat
     2161 cgaatacctc cttataatga ttttatctag ctacagtctc gacaaactta gtgtagcgct
     2221 ttttaaagca acgacactca aaaatcttga atggttctta ttttgtcgtg aatggtcaat
     2281 ttttcttctg aaattaccag ttaagatcat atggatacct ttcacgagct atatcttttt
     2341 ctctcttttc ttatgatata attgattttt gcatgtacat catatctctg agcatcatta
     2401 gaaaccaact gttacccctt tttcttagtt ttgactaaat atatttataa taaatatccc
     2461 ttaaggtaaa tggtatcaac gaggttgatt aaaaaacaaa tgatggcttc cacatggcat
     2521 tcttttactg tcaatgcaaa gccttaatag acgcctcaag tgctttcatt tttagtcttg
     2581 aaaccatgca agactgccca ttcttgaaat agagtaaacg cttatcacga tcaagaaacg
     2641 aaacattgta aggattgata acataagaac gatgacattg gactagtctg gaatcttgct
     2701 taagaacctc tgaaagaaag ccataaaatt ctattcgctc gttttgagaa tgcaaaatca
     2761 acttgtgagg agtactagag gtctcaatga acaataggct tgaaaaagga acctgcacct
     2821 gagccttagc cgttgcaaaa ataaataagc cctctgaggt tacattttct tgctcttcat
     2881 aagcatatat aatggctctt tcaatcctat ctgagaaatg tttcattgac aattccttat
     2941 cgataaaatc tagagcagac acctgataac gaaaagaaac tggcataagc tcagaatgtg
     3001 tggtgacaaa aacaatgagg gcataagggt cacgctttct gatctcacga gcaacagcta
     3061 agcccttttt ctcatcattt cgaatttgaa tatcgagaaa gaaaagctga tgcctgcctc
     3121 tctctgtaac atttgccaga agctggtagg gctttccata aacttcaaaa cgatcacaag
     3181 tccagtgatg cttatccaat atctcttgaa tcttcatctc aagcctaaac tgttggccta
     3241 gatcatcttc gagaataaaa atattcattt agaacctcct tattgcttta gcttatcgtt
     3301 tttttaggag actaaagcag ctttttgaac aagtgatagc tagaacgctc tccttcatga
     3361 acagtatctt tttagcatca ccattaaaac catgaccgtt aagcttatta actaaaggtt
     3421 gtcaatgact tctaaccaac ttgtcattgc agcgttttca ataggcctta gcgaatcacg
     3481 cgcctcaaac aattttttta ccacagataa tatactagca cgagccgcaa gtcatacctc
     3541 tttgagagag agctcttaac gactatcact tttgtttgac aagtcatcag ctatcaatcc
     3601 acacactgat ctccttgcac agacattcta acacaaagct agggagcagg gagttaaaat
     3661 cttaaatggt actgattatg tcttaaatgg taaataagga aaactaacaa tggctagtca
     3721 ggttactgag gctatctgat gattagctgc ttgtagctat accttctcca agcaataagt
     3781 ttctagaatt attggtaaca aatacattag gtatccggga tattctgtca tttattttat
     3841 cataaaaaca atctttttat catcaaaaca ggtaattgtt attattatta atcactttga
     3901 gtgatttgaa gtaagctaga tcttcagcta aaccttatga cactaaacac aaaaagcccc
     3961 ctaaggcagc taaaacacca gcctaggggg caagattcaa gagagtcact ctatactttt
     4021 agaccatttc aatttgcagg tatttacaat ttgttgcagc ctctaaatga taaaactgat
     4081 gagcagagat actgatcaat ccgcctgctt tcatgtcatg agcctgatcc gtaagactaa
     4141 ccagcaacct tccttctaag acaagcagga gcttaccttc agggcttgat tcgttactaa
     4201 tcgtctctcc ctgatacatg gcatataaaa caacagattg cttaaagcct aggctttgat
     4261 gaagcgaacg actagctatt tggtcatcat gataccttac taattctaat aaatcagcca
     4321 acatgctaag cctccggctt tacaacaact aaaagcatct ggaaggcttc cttagcaaat
     4381 aagctatgag gaatattagc aggcatgatg atcgtctcgc cagcagctac ctcataacag
     4441 gcttctccaa tagtaatgtc aactactcca cttaacacgt taaccattgc atctcccggt
     4501 gatgaatgac gaccgatttc ttgtccttta tctaatgaaa acagggttat gcccaaatct
     4561 tttctttgaa ctagtgttcg acttaatatt tgatcctctt caattggcac ttctgccttt
     4621 aaatcaatga ctgtgcttgt tggaatttta cgaatcaatg acatgtcact tctcctttac
     4681 cattattcta gttatttttg acttacagcg gcaatataac acagctttct tccagttttg
     4741 ttgaagaaat gacgcatctt taaaaactgc tttcgatttt cttttttcat gccgcgcagc
     4801 ataatacgaa tcgcagcgac aaccccttca tctttaatca tgccaagcgg ggacatgagc
     4861 gtcatattac cataggagta attgactgct gtgaagccac tctttaccag caattgtctc
     4921 caggcatcta actgcaatgg cgatacgttc acattaatcg tatctcttag ttgctctata
     4981 atagcctttg tttcatcagc ttcataggaa acatcatgcg ttagtaggcg accacccggc
     5041 tttaaaacac gccaatattc cttaagtgct ttttcctttg cagcatcatt caacatggtt
     5101 agcatagctt cgttaataac gatatcaaag ctattatctg caaaaggcag cttcaaggca
     5161 ttagcttggg taaggtgaat atagtcttgc atttgtgctg cctcaatagc ctttcttgcc
     5221 tccgccagta ccttggtatc caaatctact gctgtaatat gacactgata agtctgcgcc
     5281 agctcaatgg aggtcgtgca acggttgcag gccacttcca agaccttgca atcactcgaa
     5341 aactctcctt gctgaaccag ccaattcgtc gcctcaacac cgccaggccg tagtcgtttc
     5401 tttcccagtc gagctaaaaa ctggtgacca acttcttttt gagacatcac atgccctcct
     5461 atttgctctg ctatatatca tcacttagaa taaactaact gttaacaaat tgatcaataa
     5521 atgattacta caactatatc acacttaaag catatcctca atgaagctta agcatttctg
     5581 atgattgttt ttatgataaa tcatagaatt ggctcatatt tcttgtgcta tacgaccttt
     5641 tgacttgcta ttatttttta aataatatat aatctagtta tcaaaactag ataaagaggt
     5701 tttagtaatg gaatatgata agctgcccag ctggaaggat ttacctgatt tggagttata
     5761 cttagatcaa gtgttactct atgtcaatca ggtcacacaa ttgagtcaag ccacagacca
     5821 taagctactg actgcttcaa tgatcaataa ctatgtcaaa catggctata ttgataaacc
     5881 tattaagaaa aaatatcaaa aaaagcaggt tgcccgctta attgctatta gcattttgaa
     5941 aaatgtattt cctattcaag atattagtca ggtcttgacg agcctacaag cagcctccag
     6001 ctcagaggtc ttgtacgata cctttgtcaa ctattggaat aatggcctta cccaatcaac
     6061 gcctgaaatt attagctatg cttgtcaaac cgtcaaggac tatcagcaca caatgaagct
     6121 ttcaagagaa atggaggata ccaagcatga accaaacctt taaacaaagt ctcccactat
     6181 cagttaatga agaggtcgca aatagtgtga cacacgctat tggagcagct gctatgctga
     6241 tactgctacc catcactgct atttactctt accagactta tgatctcaag gctgccgttg
     6301 gagcatctat ttttatcatc agcttatttc tcatgttttt atcatcaacg atttaccatt
     6361 ccatgtccta tggaacaact cacaaataca ttttacgtat cattgatcat agcatgattt
     6421 atattgctat tgctggtagc tatacacctg ttgccttatc cttggttgag ggcttgttgg
     6481 gctatgtgat tatcatactc cagtggggaa tcacactttt tgggattttg tataaaattt
     6541 ttgctaaaac gattaatgaa aagttcagtc ttgcgcttta cattattatg ggctggttgg
     6601 tcgtttttat cctgccggtg attatccaaa aggccagtct gccatttgga atcttgatgc
     6661 tactaggtgg cttatcctat actgtcggcg caggctttta tgctaaaaag aagccctatt
     6721 atcacatgat ctggcacctt tttatccttt tagcctctgc tttacaggtt attgccatta
     6781 ttttctatat gctgtaaaaa gtagctgttg ctacttttta aacgcgagcg cttgcttacc
     6841 cccagacacc tggcttgatt catgctataa taaagggcag taaatagttg aagggatcaa
     6901 agcaatatga aaacggtaca tattttttac aatcctaatt caggaaaacc agaaaatgac
     6961 ctggctgaaa aggtcaagca ttatctgatt caaaatggtt tttctgaaga caaggttcag
     7021 attattaccc ccaaaaatgc tgatcaagcc tttcaattag ccaaaaaatc ctcacaggat
     7081 catattgatc tagtcattcc tctaggcgga gatgggacac ttaataaaat tattggaggt
     7141 gtttatgaag gtggtgctca ttctgttatt ggactcgtac cgtcgggcac tgtcaataac
     7201 tttgcaaagg ccttaaacat tccactccag ctaactgagg cacttgagac gattttatct
     7261 ggcacgatta aaaaagtaga tatttgcaag gtaaacaagg gctatatgat ttctagccta
     7321 accttgggtc tgcttgctga tattgcggct aatgtgacta cagaagaaaa acgaaaattt
     7381 ggcccttggc ctttttaaag gatagtatta agatactaaa acgaaaccgc acatatgcaa
     7441 ttagcttaat tagccatcat catgttcttc acttgaaaac caaattctta ttgattacca
     7501 caaccaatac tatagcaggt cttccatcgt tttcaccagg tgcacaagct gacgatggct
     7561 tgtgtcaagt ttacacgatg agccagctat catttctgaa atgcttgcgc catattagag
     7621 actttagacg gggggatttt tccaaggtaa aggagattag ccattttcaa gctgattctc
     7681 taaagctatt gccacaatat cagcgtcaat cagccattcc tagaactcgc attgatggcg
     7741 ataaggctga tgatctccct gttgaattga aggttattcc aaaagcgatt tccattattg
     7801 ttagccagta aaaaagtgcc ctagggcact ttttgatata gattcatctc caagctgagt
     7861 tttagaaaac taagctatag ctataacgtt agctgtggct tcttcttgct ggcttgcagt
     7921 actcttttct tgtcttaaca gctagctctt tcataatatc ggctttaaca aagaagctat
     7981 ctgactagtc cgatcttcta ttctcaggac aaacagcgag aaaggggatt ttctttgaat
     8041 cctagagaac cttagctatc tctgtgtctc attgtaagtg cagctctatt gactgatgcc
     8101 agctatagca ataagcccag tcgcatatta taaaggatta tcaggcgatt tagcttgaca
     8161 ctcttatatc tttattgctt cttctaaggt tcctttaata gctttagctg ctgaatgacc
     8221 acaggcatta gcagcaacct tagaggcttc taccttatca gaggctgtct caataagttg
     8281 tccacccttt tcttggatat aatggttcaa ctcctcaata gtttcagagc cttcctttaa
     8341 gagctctttc tttttggctg aggataagct taaatatgtc acagcaattg ctgctgaacc
     8401 aagaagtaat cctaagccga ttccatagct ttttttcatc atcaacccta ctttctatga
     8461 ccttccttaa tcatcttttt agctaatttt acagctggta ctactaaaag caccaattgt
     8521 aaaagatcca tatacttgat ttttcgtcgt tttttcacca tgtgctattt cctttttctt
     8581 gtttgcacca tacaatcgtc ttttattgcg cagtgccaga gactgcctga ttaggcagcg
     8641 taagctaaga actatcagcg tgtcagacta gtctagatac agctaagcac tagcttgatt
     8701 acgataatac ttaccgctag gccataagct cagctatcat caaatctaaa gtgacaacgc
     8761 tttttattta ttatattgtc attttactaa aatacacaat tatcgtcaat gcttttgctt
     8821 taggcagcaa aaatgcccaa gataaagacc ttggacatct gctacaatga cgttaattga
     8881 ttgaaatccc aaatatcagt tacccagccc tcataaaact ccggctcatg gcaaaccatc
     8941 aaaatagagc ctttatagac ttgcaaggcg cgttttaact cctccttagc atctacatct
     9001 aaatgattgg ttggctcatc taggattaaa acattgtgct cacgattcat taagagacaa
     9061 aaacgaacct tggcttgctc accacccgag agcccctgaa tctggctttc aatatgctta
     9121 gaggttagac cgcaacgagc taaggctgcc cgaacctctg cttgatttaa agcaggaaaa
     9181 gcgtcccata ctgcttctag tggcgtttga cgcttaacac ctgcagtttc ttgctcaaaa
     9241 taaccaagct ccacgaaatc tcctgtttcc acctctcctg acagtggctg aataatgcca
     9301 agcaggctct ttaggagggt tgacttacca ataccattag caccgataat tgcaactttt
     9361 tgatgacgct caaatgttaa gttcaaggga tcttttgtta ggggtctgtc atagccgatg
     9421 acaagctccc ttgtttggaa aataaagcgg cttggtgttc ttgcttcctt aaactcaaag
     9481 cttggctttg gtttttctgc ctgaagctca atgatttcca ttttatcaag cttcttttga
     9541 cgggacatag ccatattgcg agtagctact ctggccttat tacgattgac aaaatcctgt
     9601 agctctgcaa tctctttttg ctgacgctca taggctgcct ctagctgagc ttttttcatc
     9661 tcatagactt ccttaaactg atcgtaattt ccagaatacc taaccaaatt ccgattatca
     9721 acatgataaa caatattaat gacatcattt aaaaaaggaa tatcatgtga aatgagcaca
     9781 aaggcattgt cataatgctg taaatagcgc tttaaccact caatatgctc agcatcaaga
     9841 taattggtcg gctcgtccag cagcaaaata tctggcttct ccagtaacag cttggccagc
     9901 agaatcttgg ttctttgccc tccagataag gaggtcactt ctgtttccat cccaaaatcc
     9961 ataactccta aggcacgcgc aacctcatca atcttagcat ctagggtata aaagtccctg
    10021 ctttcaagac ggtcctgtag ctctccgacc tcctccatta aggcgtcgac atcagctgtc
    10081 tcctctgcca tagacatgta aatggcattg atacgctcct ctgttttgaa tagctcatca
    10141 aaggctgtcc taagaacatc acgcacagtt tgaccaggtt ctaaaacggt atgctgatcc
    10201 aaatagcctg ctgtaacata ctttgaccat tcaatcttac cagcatcagg ctgcaagtga
    10261 ccagtaacaa tactcataaa ggtggacttg ccttctccat ttgctcctac taatccaata
    10321 tgctcgccct ttaaaagacg aaaggaaaca tcttcaaaaa tggcacgatc accaaatcca
    10381 tgacttaact gcttaacttc taatatgctc atgattactt tcctttattg tcatcaaaaa
    10441 agccgttaaa acggcttaca ctctctcaat tatggcaaaa atgcagcctt ttgtcaatga
    10501 aggctgaaaa agcctacgtc atacgcatga aagattttta gcaagaacag aaggtttttt
    10561 gcattttaat gttcagctat ttcaaatatg tcttattatt ttataaattt tactataggg
    10621 aaagccttga aagtgcctgc tttaatttat actatcattc ggaaagaact gtttcgctcg
    10681 tttgttgtgg aaagccgctc acaacaaaga catagagagt ctatgacaac aagagctaca
    10741 ctttagcaag tcttgaccga catgctttat tgcccagtct aattcattaa aaagcgaaca
    10801 ggtctagctt tcggaatttc agaaaactag gcctgttcat ttgttctatt ttgaggcagc
    10861 cttttgtttc ggcctcgtct gtttcaaggt tttcagatcg aacttaagga caaaaaacac
    10921 tctcctgtat cagctaacct tatcattcat tataaaggaa aatgatttct aatacaagga
    10981 aataccgtta tttcattaaa aataactaaa aatagtttgt caaatcatta gttattaata
    11041 ggcttagata acaaaaatga tgatactgct agcaaggtta gctcaaccaa gcctattact
    11101 cgcttcttgc ttttttactg cctgccttaa ttgcttaaaa acagggtata agagaggcac
    11161 agcaataacg gtcacaaggg cagtaccaag actgccacca attttgccaa gtgctgccca
    11221 caaagcaaca gacaggggta actgggcgcc aaaataagca atcaagctat atttcacaag
    11281 attcatgact aattttgctg ctgctgctaa taagccaatt gctacaataa tcatcggttt
    11341 atcaactgat ttcagaagtt tctcataaat cacatgaagc aggtaacaaa ccactaaggc
    11401 ttcaagcact gttatccaga ccacagccgc atagccatta atcatatcaa acagtcctag
    11461 accaatggct gccaccaaag ctgcccttct agcaccatac aataaaacag ccaccaccac
    11521 taaggcattc cctaggtgaa taaattgggc tccaactgga atacgcagca gctcaaccga
    11581 tataaaaata agagcagcaa ataggctaag ctcgatctga tcagtcaatc gttttgatgt
    11641 catctttttc ctccaataat cctctaaacg cggctcccaa gctgcccaat tctacttcgt
    11701 aggcaattcc aagtgaaagc tctcgattta gcgcaacagt agccgctaat gacttgtcta
    11761 agaagctaat aaccatatcc aacaactcat caatagcaag cctgtgaaaa tacccagcgc
    11821 taacaatagc agagacaaga tcacctgtcc catagaaatg ataagggtac cgttttccaa
    11881 aatgatagct aaccgtctct gttgcctttt gataataagc aaagccgatg tgctgatcat
    11941 caaaggatat accagtaagg acaatctctc taggtcctag tgtagctagc ttagacaata
    12001 gcctctccaa atcctctctg ctataggtct ccccaaaata aggaacatca gctaacaaac
    12061 aagcttccgt cacatttggc aatatcagct gtgcagcttg agcgagcaat ctcattgccg
    12121 ataagtgctg cgaggttaac tgcgcataca tgcttccctt gtcagccata ataggatcta
    12181 gcacaaaggg aagctgttgc tttttgatgt aatcaagaat aatcaaagca tcatcaggac
    12241 ggtacaaata accggaaaaa aagccatcaa aggcaagacc cgcttgagac caagtcgtca
    12301 aaaatggctt tagtccctct gacgtgctct gaatataagg cgtcttagca attgcagtgt
    12361 ggcttgataa caaacaggtt ggaagaatgg cctgttcaat ctggcaagcc gccataatgg
    12421 gaatactagc agacagagca accttgccaa ctccgacaat atcatttgca acaataacac
    12481 gttttaacaa ccaataagct ccttcatttc tttttttact attgtaagaa aatccttgat
    12541 gagatacaat aaggatagat ttcatctgta tggggacact tatgacaagt aaatatcaac
    12601 aaatcattgc agacctagag ttggccatgc aatcaaacca attcaaaaag ggagagaaac
    12661 tcccttctat tagacaatta agtcaacagt atcactgcag caaggataca gtgcaaagag
    12721 cacttttagc cttacaatac aagcgcctca tttatgctat tccaaaaagt ggctattatg
    12781 tgcttggtaa aattgaggaa aagcagcatt cctttgagct aagccttgag gattataatc
    12841 agttggccta tgaggacttt cggctctgtc taaatgaagc cctagacggt aaagattctg
    12901 atttatttaa ctactatcat aaggctgagg gacttgagga gctgcgagag gctttgctgc
    12961 cttatttggc tgataatggg atttacgcta acaaaaatca gctgctaatt acctcgggta
    13021 cacaacaggc cctttacatt ttagctcaaa tgagatttcc caatggccgc catcacattc
    13081 tccttgagac accgacctat caccgaatgg agcagctagc gacttcctta ggcttaccct
    13141 atcaaaccat tgaacgtgat gtcaacggta tcaatcttca tcagcttgaa agcatcttta
    13201 aaaccggaca aatcgctttt ttctatacta tttctcgatt ttcaaaccct cttggcctct
    13261 cctacagcaa aaaagaaaag gaaagcattg ttcggctggc agagcaatac caggtttaca
    13321 tcgtagagga cgattatcta ggggactttg catcgcatag tgagcttccg ctacactact
    13381 acgacactca acaccgggtc atttatctga aatcattttc aatgagcgtc tttcctgccc
    13441 tgcgcattgg agccttgctt ttacctgatg atctcaagga aggctttttg ttacaaaagt
    13501 caatgattga ccttgatacc aacctgatca tgcaaaaggc actagcatta tatttagcaa
    13561 atggtatgtt tcaaaaaaac ctaaagcaaa tgaggcaatt tttcaacaat agagcgcata
    13621 acttactaga ttttctacaa aaacaccttc ctaacctagc ttatcagctc actcctcaag
    13681 cactgattat tcaattagat aaagcattca atcgcaaaaa gcttcttaaa ccacaccaca
    13741 cccaaatcat ctcaacaaga aaagcaaggt atatgcttct aacaatcagt cctgatatgc
    13801 catctaagct gctcgacttg ttttcagtga cacatgaaaa gacccaagaa tagctcattg
    13861 ggtctcagtg tcacaaaaat gtcaatagct atttgatttg ctcgaatcgt aaatgaacac
    13921 taatgctatc gccgtaaccg tttctctcca aatctctttg gagccggtaa gcaatataat
    13981 gctctgcaat agtcatgtag cctgcgtcaa tcagacgatt ttcaacaagt gattgaatca
    14041 tattaatcgt cggacgctcc gcctgcacct cttctagatc aataacaacc tttttagtta
    14101 cctgagctag atgctgtctc cagctgtcat caatcacata aactgttctt gctgccttga
    14161 tcaaagcctg ataaatctta tccggatcaa agtctgccag ctgaccgtca cgcttaataa
    14221 tttgcataag agcgcctctt ttcatttagt ttcattgctt acattcatta tgcaaatgtt
    14281 ttcatcattt gtcaagctat taggctccta tgcctcttag ggattatcag tcaaaagaaa
    14341 cactaggatc aaataaattg tcctgtgctg gtcggacaag cccacgctcg tgcaaggtct
    14401 ctgcaatctg aacagaattc caggctgcgc ccttgagcag attgtcagat accacccaca
    14461 tgtgaatgcc cttttcaaca tctaaatcct tacgaagcct tcctacaaag gtctcacgac
    14521 tgccaacagc attaacggcc tgtgggtatc gttgcactcc ggtatcgtcc tctaaaacag
    14581 cacccggaaa ttgtgcaatc gcctccttaa cagcttcgat agtagctact gccttggttt
    14641 caatgtagat agattctgaa tgggctgata aaacgggtat acgaacacag gtcgcagaca
    14701 ccttaatcgt atcgtcctcc atgatttttt tcgtttcatt tgtcattttc atctcttcat
    14761 aggtgtagtc attttcagtg aaacgatcaa tctgtggtaa agcattaaaa gcaattggat
    14821 aatgtctctt gtcaccagct gacggtaaaa cacttgcctc cacctcctta ggagacaagc
    14881 cctggttaat aacctggtca tactgagcta gggtctcacg aatcgctgat tgaccagcac
    14941 ctgaaacagc ctgataggtg gaaacaataa tacgctcaag accccacctt tgacgaatag
    15001 gctccagcgc tatcatcatt tgaatcgtag agcaattagg gcaagcaaca aggccttgat
    15061 gtgtatcaag agcgtgagca tttacctcag gaacaacaag tggaacagct gggtgctgac
    15121 gaaaataaga ggtattgtca accacaacag cacctgccgc aacagcataa ggggcatatt
    15181 ttgcagaaac attgcctcct gctgaaaaaa gggctagatc aatgccttgg aaggctgctt
    15241 ttgttagctc ctcaacaaca aaatcctctc ccttaaatga gaggattttt cctgctgaac
    15301 gtgcagacgc taataattta atagctgaaa taggcagact tgactcctcc agcatcttaa
    15361 tcatttgctg accgacagcg cctgtcgctc caaccactgc tactgtatac cccatagatc
    15421 gacctcactt taactgatga tattgcaaaa aatgatattg gacctattat agcctatttc
    15481 atcacaaaag aaaagcaagc tagaagccag aacaaacgca tgaagaaaat catttattga
    15541 aaaagttgtg aaaatagcaa aatatccatt ttagagtatt ttgacagagt gtttcctgaa
    15601 tttttatatt tttcctctat aaacttttct tgaaaaa
//
LOCUS       DARYJX010000048        15116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYJX010000048 DARYJX010000000
VERSION     DARYJX010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TU257_001717"
     CDS             complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TU257_001717"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL0834707.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2577..3230)
                     /locus_tag="TU257_001718"
     CDS             complement(2577..3230)
                     /locus_tag="TU257_001718"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834708.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3270..3899)
                     /locus_tag="TU257_001719"
     CDS             complement(3270..3899)
                     /locus_tag="TU257_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0834709.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3901..4902)
                     /locus_tag="TU257_001720"
     CDS             complement(3901..4902)
                     /locus_tag="TU257_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0834710.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4935..5576)
                     /locus_tag="TU257_001721"
     CDS             complement(4935..5576)
                     /locus_tag="TU257_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL0834711.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5611..6405)
                     /locus_tag="TU257_001722"
     CDS             complement(5611..6405)
                     /locus_tag="TU257_001722"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL0834712.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6714..7148
                     /locus_tag="TU257_001723"
     CDS             6714..7148
                     /locus_tag="TU257_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0834713.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7148..8347
                     /locus_tag="TU257_001724"
     CDS             7148..8347
                     /locus_tag="TU257_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL0834714.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8393..8881
                     /locus_tag="TU257_001725"
     CDS             8393..8881
                     /locus_tag="TU257_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL0834715.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8896..9675
                     /locus_tag="TU257_001726"
     CDS             8896..9675
                     /locus_tag="TU257_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0834716.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9662..10483
                     /locus_tag="TU257_001727"
     CDS             9662..10483
                     /locus_tag="TU257_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0834717.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10883..11884
                     /locus_tag="TU257_001728"
     CDS             10883..11884
                     /locus_tag="TU257_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0834718.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
     gene            12474..12740
                     /locus_tag="TU257_001729"
     CDS             12474..12740
                     /locus_tag="TU257_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0834719.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            12752..13111
                     /locus_tag="TU257_001730"
                     /pseudo
     CDS             12752..13111
                     /locus_tag="TU257_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13102..13983
                     /locus_tag="TU257_001731"
     CDS             13102..13983
                     /locus_tag="TU257_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834720.1"
                     /translation="MGVTYSAAESKALIQAMTNNIQIANEITDRLSSGCDHLIASLDS
                     GELQGAAYTAGRGLFTAIIIPSIKKLQAAIDAIQVELTTYQRADAQIARYGTLDRDHL
                     TELKRLRERQVQVIQAQIDENESFMKQVSSLLTGDYGTLWSDTSTLYHAKNQLEIGIR
                     DVTTKLESLEWFLTQTSDCFRDSLVILRLAIQGATQLSQVFMSSDGSYSTAGLDMSWV
                     TSLKNQKISPVNASKYTQNHYHNILTQTIKTIKSSSERPLQKSERLVAAYEDYLYFLN
                     KTAFDDYWKARSNYDGE"
     gene            14065..14508
                     /locus_tag="TU257_001732"
     CDS             14065..14508
                     /locus_tag="TU257_001732"
                     /inference="COORDINATES: protein motif:HMM:NF026945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834721.1"
                     /translation="MIVNKMGDDILSVNVNAPYLSQVAGSQLSAAILDNKQFYDLVNT
                     GQPLDLKSRTYHGHNYSVWSRQWESELPGDYAGNYLYGYVGTGFLDASGTYLKTAAEI
                     AQVFSDKDIPKWLKNLSSGHYGDNEGDTQMIQAGIDGYMKRKKSK"
     gene            14505..15011
                     /locus_tag="TU257_001733"
     CDS             14505..15011
                     /locus_tag="TU257_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834722.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
BASE COUNT         4355 a         3363 c         3096 g         4302 t
ORIGIN      
        1 gctcaggggg gattttaact tattactaat gtgcttgaat ggctatgata aggccttaaa
       61 agatagctgc ttaaagtcat ttcccacctt ttgatagagg tataagcctg atttttcaag
      121 actcaattga ccattaacca cctccttagc ctgattgtat ttgaccaccg ccaacaggcc
      181 ttgtttctta tcatggatca gctgaagctt actgtcattt cgaagcacct caatacgtgc
      241 ttcgctgcac accttgtcaa agtctgcttt gctgatattt ggaagtaggg tgtaggcata
      301 gctatcacta gcctgagaat gagtttgact gattgtgata aagctttggg agatgaggtc
      361 tttattgtta ctatttgtat taatctcaga ccaacagcct gactgcacct ttcgcgatag
      421 cgctaatgcg gttggcttgg caaaaaggta accaatatta gcttgaccgt ctttagaaag
      481 tagtaaaaga ctggtcacat catctcgata caggatctcc tctgttagcg ctgtctcctg
      541 cccattgata aaaagagtgt agctgttgtc tgggttttct ttgcgttgat caatggtagt
      601 agtcactgcc tgatgtgtct gactagtgat ggcggtgcca agaaaaacaa tttggtcatc
      661 taagatcgtc caagacttct tggcactcac tgtcctatcc caattttgaa aatccataac
      721 agctaaagct gttttgtctc ccgccttgat cgctccaaca aaggacgatg gcagggtaga
      781 catgcctgct ttttctttgg ccttttcttt ataatcattg gttagctttt ttaaataggc
      841 tactgtcacg tcctctcgcc tgacctctgc ttccgttgtt ccagccatct ttaaaggatt
      901 aacagtcggc caaaagtggt ctgagtaatg acccaaatca ctgttataaa ggtaaaacat
      961 gccatctcct gtataccaac cacgtgtatt ttcatcgttc atggcttcaa aattcagagt
     1021 tttgttggaa tgcatggata aagcaaaggc aaaatccttt tccgcattgt agtaggccaa
     1081 tttatccatc tggttaaaaa gagataggta gctcttaact ggactggctt ggattgtggt
     1141 atcctccaag agctctttga atagcttcat gtcatagtag cttgataggc tctctaaaat
     1201 agtctcctga ttatggaagg ccaaaacagc cttgatctta cccttgatcc tgattttagc
     1261 ttgctctggc aatgcctcag ccagtcttag cattcctctt agtgcttcta aggctgcctg
     1321 ccttgaggag gcattttcac gactgatgga gcgcccacga ctcatatcca tgagctcccc
     1381 atgaaccatc aagggcaaga aggcttgctc aatccaatga gtcatgacct ctagcttttg
     1441 ctggtctagg ctagtagcta atagctgaag taatggtacc agctgagaca agccatcaat
     1501 aaggacattg ccataggctc cagtgtaggc gacattggta tggtcaatat aagagccatc
     1561 ttcataaaag ccctcacccc ttgatccctt tggctgaaaa gcaaataagg tatctagggc
     1621 tgctatactg tcttgaagcg ctttcttatc atgctttaac agagcttcaa taatcttcac
     1681 tcgtcccata tcaacaaggt tacccccaat ggccttaaaa ggattcacaa gggttaagcg
     1741 aaattgtcta ggattaggaa caaagtgaga aattccttta gtatagcgct tgatctcctc
     1801 ttgagtgaca taagggtaaa tgaaggctag ggtattgaca atagctcttg gggtaccaat
     1861 ttcaaaatcc caccaattag ccttgccttc aatatccttt tgcggatgat agtaattaag
     1921 tgtcagccag gctaatttat ccttgatcag tcttatcagc tccttatcct gataatacct
     1981 agaggctagg ctactcacct gcttggccat ttcctctaaa cgcctacagg tagctgtcat
     2041 atgagacgat tgatgaagat ccgccaaatc actccaaagg tatgtgcttt tctgatcctt
     2101 ggtcagatca gctagattct tggtcacgct gtcgtccagt ttttggttta atgccaccat
     2161 ggctggactt gatcggtcaa agttttctgc tcccaaaatc acctcacacc actttgtgat
     2221 caaggaggtt gtttgagggg cttctgctgc taaaatctca actggtaccg ttgctactct
     2281 ttgcccctct tgatccaaca cctctaaaag cgttttcccc tgcgccaaag gaattaaaag
     2341 accattttcc acgcgcacaa tgttgctgga ctccgctgca atctgataat gatagtcagc
     2401 catttccatg aggtagtgct tatttaaagg caggacgatt tgctcctcta agtaatgtga
     2461 agcaatcttg atgtcatcac ttggcttatc accagcctct ctcaaagaaa ggttatcaaa
     2521 gaccacctgt ccatgaccgg cctcataaaa gagctctagc ttgatttgat taacctttag
     2581 cttagggata taaagctttt cttggtgttt tttctcagtt cctgttgcca tcgaagccac
     2641 aagcgttgct cttttgcagc accagaacct tgctttattt cttcaatgat acgcgcaaaa
     2701 gcctgacctg ttttatcctt tgtctcaatg tcaaaggtca gcaaatactg cttgtctgga
     2761 ttgatggcaa cggtttggtg cacacagcct ctaaatctct gattgccatc gctagtcatt
     2821 gtcagcttgt tatcagagac agcaatttta ggacagccct gactcttact agcgtcctta
     2881 taatccttcc aatcatttgc agactccttg ctccaaaggc ttgtactttg atgctcttga
     2941 gcaggactgg tctgatcaaa ttgaggattt ttaagcaggt tatcacctgt gagaatgagc
     3001 tgctccccaa gactggattc cgtagctact gacgacgcgt cttgagtgtc tggggagctt
     3061 tcttgagaag cctcctcagt ttttagtggt gctttcttta ccctctgaag ctccttggaa
     3121 atggcttttg ctgctgtttt ttcttctgct aagactgttg gtgcccgaaa taaacaagct
     3181 agtatgatac tagagcaaac agaagatgat agtttttttc tttgcttcat ctgatacctc
     3241 cttgcttttt taatgtttta tgaccgactt taacagctac tcatgtaatc tgcagccctt
     3301 gctgtgattg cctgaaattg accctgagct gccaattgat taaattctcc tccaactccc
     3361 agcacctgag cacctgcggc aaaccagtct gacacatttg tgacagttac gccacctgtt
     3421 accatgacat caacctgcgg caaaggagat ttgattgcct taataaagga catgccaact
     3481 gtggcacctg gaaagacctt gaccatctct gcacctgatt ccaaggcagt cacgacctcc
     3541 tcaatagtca tacagcccgg aatataagca atagcatatc gatgacatag gcggcttgtc
     3601 tgcctgctaa agctaggaga cacaataaat tgagcacccg ctaaaatagc tagccttgct
     3661 gtgacatcat caagaaccgt cccagccccg atcaggatct ctggatcatt gccaactgct
     3721 tcacgcaggc ctgcaataac ctgactggca aagggattag tataggccac ctcaatggtt
     3781 ttgatcccac cttcaatacc tgctaggctg caagccattg cttctttttt agaagctccc
     3841 cgaacgacta aggctaattt attggctttt agccttaaca tgatttctga ttttctcata
     3901 ttaccttctt acctctcggt ttcccttcat caccctatca acctgactaa caggaacaaa
     3961 gagctgatca tcagcaactg tacacttaag actagctgtc gcagcagcaa aatcaagcgc
     4021 agcagcaata gcctgtcctc tcatcaattg atataagcag cctgcaacaa aggcatcacc
     4081 actgccaact cgttgcaaaa caggcgttga tagctcaatg gagcgatgta actgcccatc
     4141 ataggcatag gctaggtaat gattgattcc ttggtcatcg atgtgacgtt ccgtgtgaaa
     4201 aatggctttt aagtgatatg cctcatataa ggcagccaag cgctccttga cagcaccttg
     4261 acctgcctta gctctatcaa acatggcatg atcagcttga ttacacatta agggctccat
     4321 accaaagatc aggtctgcat actgtgcaaa atgagagaac aatgtctttg cctccctgac
     4381 tgaaatcatc gagctgcgaa aattcaaatc aaaggaaaca cagacctgcc gcttcattgc
     4441 ctcaatagcc agctgctcaa caaggtcctg actgactttt cctaaagcca aggtaatgcc
     4501 actaaaatga aaatgagtaa cttcctcaaa tagtttacca taatccagat cttttgggcc
     4561 caataaacta aagctagagg cagagcgatc ataagcgacc tgactaggac ggcagccaaa
     4621 gccattttcc aaataataaa taccaacccg atcaccacac cattgcacat gctctgtggc
     4681 aacaccgctt tgcttcaaaa aggcctcaac gcttcgtcca acctgattat caggaagggc
     4741 agtcagcagg ctactctctg ctctaaagcc actaagcgtt cttgcaatat taacctctga
     4801 gccaccataa tacagctgtg cttgacaggc atgtcctaac gtctgaaaat gactgggact
     4861 gatgcgaatc agcggctctc ccaccaataa taccttggtc ataggggtat cctttctata
     4921 gctgcagata agacttattg ctgaaggact tctcttaggt agtcgacaag gtctgatggc
     4981 tcggcattag caaagaaata atgctggaag tgctctccag aaatggtttc cttcaagaaa
     5041 tcttgatcaa tctcctttaa cacctccaac aaagaacgat aagtcacagc cttcaattcg
     5101 ctcaaaattc tagcgttacg ttgctctggg atggcccgct ctttgggata gccgcccccc
     5161 atcggctcag caaataagcg ctcaaacatc agggtcaggt taagctctgc cccccaacca
     5221 aagccctttg caaatggaat agacaaggca ttgccaccat taatctgagc aaaaaggtag
     5281 gcttctgttg gctcactagc aaagccacag gtcacacctg gaaagctatt taaggccagc
     5341 atagcaccca caccagtccc acagcccgtt acaacaaaat cagctgcctt acttgtcaat
     5401 aaaatagaag ctagtagccc gttttgcaca taggtcagct gactttcgcc ctccttgcca
     5461 tacataccat agttaaagac ctcatagcca tgcttattag taacagagac taaggtctcg
     5521 taaataatac tgtttttagc tgcttgactg ttttcattaa ttaatgcaat tttcatcttc
     5581 tgtaatctcc tttgatgctt ttttgtttct ttacggttgt ttgccaatgt aagctaaaat
     5641 gcctccatca acataaagga tatgcccatt gacaaagtta ctcgcctcac tagccaaaaa
     5701 tatagctgga ccagccagat ctgctggtgt tccccaacgc gctgccggag tcttagcaat
     5761 aataaactga tcaaaggggt gacggctgcc atcagcctga cgctctctta aaggtgctgt
     5821 ctgaggcgtt gcaatatagc caggcccaat gccattgcac tggatattgg cttctccaaa
     5881 ttctgaagcg atgtttttgg ttaacatctt aagaccaccc ttagctgccg cataagcact
     5941 aaccgtttca cgaccaagct cactcatcat cgaacagata ttgatgattt tcccatgccc
     6001 ttttttaatc attgatggca gaactgcctt tgaaacaata aatggcgcat tcaggtctat
     6061 atctaccacc tgacgaaaat ccttagccgt catctcaagc atcggtgtcc gtttaatgat
     6121 acctgcatta ttcacaagaa tatcaataat accaacctct ttttcaatct gagccaccat
     6181 ctcttgaatc cctacttcat cagtgacatc acaaacatag ccatgagctt taatgccaaa
     6241 ctctcgataa gctgctaatc cttgatccac taaatcctgc ttgatgtcat taaagacgat
     6301 ctttgctcca gccatggcat aggccttagc aatctcaaag ccaatcccat acgaggctcc
     6361 cgttatcaag gcaattttgc cctctaaaga aaagaaatgt tccattgttt tacctctcaa
     6421 tctcaatatt taagtaaacc tgtttatcaa aactatagca agactaatcc attttgtcaa
     6481 tcattttagt aaaaacacaa aaaagagcta aagtttttct tattgtcatt atcgaggaag
     6541 gcttcttagc tatatttttc ttgctcttac tcgctttact tcctataagg atcccaaaaa
     6601 ttaggccata ttgatcgctt attttgataa aataacaaaa aagtgttgac aaacattttt
     6661 gaaagcgcta taatttttct gagtaaaccg gtaaactaaa aaggagctta ttcatgattt
     6721 ctattattgt tattggtcat gggcattttg ccagtggtat tgtctcgtct ttagagttaa
     6781 ttgcaggcaa gcaagagggc ataactgcta ttgattttac tgctgagatg accgctgctg
     6841 atgtgcatga gcgcctatca gtagtcttac agtcaaagac tcaggcactt atgctttgtg
     6901 acttattagg cggcacccca tttaaggtag cagctacctt gatggaggag ctttctgaga
     6961 gcacacttga tgtcctgtct ggactcaatc tagccatgct aatagaagca gtctttgcta
     7021 ggcaagagca gcttgatcta gaacaaattg tcgctaagct attaaccaca gccaaggaag
     7081 ggatcagtaa ttggaaatcc ctctctggtg aggctgatga agcagacctt gatgaaggag
     7141 ggatttaatg actagacaga tcaaagaggt tacccttgag cctctcatac aagcagaggt
     7201 ctatagccag cagccatatc taacaaaagc tgatattgag gcagctattt tattagccct
     7261 taagcaaatc cgattaaaca tggattattt tggtactgat ttccctaggc cagccactaa
     7321 ggacaattgc tacccaatta tggataatac cgagtggacc aatggctttt ggaccggctg
     7381 cctatggctg gcctacgaat acactggtaa tgacactatc aagtcactag cacaggcaaa
     7441 tgacctgtcc ttcttagaac gcgtcaccaa agacattgag cttgaccatc atgatttagg
     7501 atttctttat tcaccctctt gcatggctga gtggaagctt ttaaaaacac ctgaagccag
     7561 acaggcagcc ttaaaggcag cagataaatt gattgagcgc tatcaggaaa aaggcggctt
     7621 tattcaagcc tggggacaac tcgggaaagc agaagattac cgcttaatta ttgattgtct
     7681 tttaaatatc cagctactct tttttgccag tcaagaaaca ggagatgaca ggtatcgtca
     7741 aatggctatc aatcactttt atgcctcagc caacaatgtg attcgtgatg acgcctctgc
     7801 ttatcatacc ttctactttg accctgaaac aggtgatcca atcaaaggag ttacacgcca
     7861 aggctacagt gatgactccg cctgggccag aggacaagct tggggaatct atggaattcc
     7921 cttgacctat cgcttcttga aggatccaca gctaattgcc ttatttaaag gaatgacgca
     7981 ctatttcctc aatcgcttgc ccaaggatca ggtatcctat tgggatttga tctttgaaga
     8041 tggcagtggt cagtctaagg acagctccgc aactgctatt gctgtttgtg gtattcacga
     8101 gatgttaaaa catttaccag agaatgatcc tgacaagaaa gcttatcaag ctgccatgca
     8161 ctgtatgctc agatcattaa ttgatagcta tgccaacaag gacatcaagc ctggtgctcc
     8221 acttttacgt catggcgttt actcttggca ctctggcaag ggcgttgatg agggaaatat
     8281 ctggggagat tactactatt tagaagccct gctgcgcttt tacaaggact ggacccctta
     8341 ttggtaggct gatagcattt agcctacaaa gactattgtt aaaggagata ttatgacacc
     8401 accaaacatt atcatgacca gagttgatga gcgtttgatt catggtcaag gccagctatg
     8461 gatcaaattt ttaaattgca acactgtcat tgtggctaat gatgccgttg ctgaagacaa
     8521 aatccaacag tctctgatga aacctgtcgt tccatcaagc attgccatgc gctttttttc
     8581 cattcaaaag gtgattgacg tgattcacaa agcaagccct gctcagacaa tctttattgt
     8641 tgttaaggat ttagaagaca tcaagcgctt ggttgaagga ggggtgccca ttaaagaggt
     8701 caatcttgga aacattcata aaacagacga taaaatcgcc attacccaat tcatttcgct
     8761 aggcgacaag gacaaggcta ttattcggac attgactcac gatcatcata ttgtctttaa
     8821 cactaaaaca actccagctg gcaatggtgc ctctgaggtt aatattttag attatattta
     8881 agaaaggaaa ttgatatgga tatcaatttg ttacaagcac ttttaatcgg tctttggaca
     8941 gccttttgtt tcagcggaat gttacttggt atctacacca atcgctgtat cattctgtct
     9001 tttggtgtcg gcattatctt gggggacttg ccaacagcac ttagcatggg agctatatct
     9061 gaattagctt atatgggatt tggtgtcggt gctggtggta ctgtgccacc caacccaatc
     9121 ggacctggta tctttggtac cttgatggct attaccagtg ctggtaaagt tactccggaa
     9181 gctgccttag ctctttcgac accaattgcc gttgctattc aatttcttca aacctttacc
     9241 tatacagctt ttgctggtgc tcctgaaaca gctaaaaaac agcttcaaaa agggaatatt
     9301 aaaggcttta catttgccgc caatggtacc atctgggctt ttgctgtgat tggcttagga
     9361 cttggtttat taggcgcctt gtcaatggat actttacttc atttggttga ttatatccca
     9421 cctgtcctcc taaatggatt aaccgttgct ggtaaaatgc ttcctgctat cggttttgct
     9481 atgattctat ctgttatggc taaaaaagag ctgattcctt ttgtcttaat tggttatgtc
     9541 tgtgcagctt acctgcaaat tccaaccatc ggtattgcca tcataggcat tatcttcgcc
     9601 ctaaatgaat actacaacaa accaaagcat gcaacaacag ctgaacaagg aggtcaacaa
     9661 gatgactgga tctaataagc tcacaaagcg tgattatctg aaaactgctc ttagagcctt
     9721 tttcctgcaa aatggcttta actatagcaa ttatcaagga ataggctatg ccaatgtcgt
     9781 ttacccagcc ctaaaaaagc attttggcaa tgacaaaaca ggcctttaca aagcactaga
     9841 gaacaattgt gcattttaca atacaaaccc tcatttccta ccttttatca ccagcctaca
     9901 cctggtcatg ctagaaaata atcggcctga agaagaaacc cgcaatatca agatggcact
     9961 catgggacct ctagcaggca tcggggatac ccttacgcaa ttttgtttag caccactctt
    10021 ttcgaccatt gctgcttcct tagcaagtga cggcctgatt ttggggccaa ttctcttttt
    10081 cctagccatg aatattattc taacagctat taaaattggc tctggactct atggctacaa
    10141 ggtggggaca agctttattg ataaattaag cgaacaaatg gcaattgtat ctcgcatggc
    10201 aaatattgtc ggagttacag tgattgctgg tctagctgct acttctgtta agatatctgt
    10261 tcccatcaca tttgcagcag gcaaggtcga cgctgcaaat gcagcccaaa aatttgtgac
    10321 cattcaggga atgctggata agattgcacc agctcttctg ccagccctct tcactctctt
    10381 gatgtattac ctcattaaaa cgaaaaaatg gacaacctat aaattagtta ttctaacagt
    10441 tattattggt attgttggca gctggttagg ggtgttagcc tagcagtctt agagattctg
    10501 ttaatcagta ttggagggtc tccattagcg atgagcaggt ctcttttcta ttgggcaaag
    10561 ctaagcattg acaccatcaa ctctcgtagc ctcagtcagg tcttttgccc tgtagagcct
    10621 ttaagcacaa gcctttactg ctagctgtga tgaaggcgtc ctccttctac tggcttctgg
    10681 cacaattaat cctttatatc tctacaagca catgatttag cggctgattg cgcgccaatc
    10741 ttacagaagg tcgcaactta agaaagagta ggatcatttt tgacctcttc aaaggtcata
    10801 ttcttggact gaaatattaa aacaattacc attccatatg ttataataaa actactaatg
    10861 atgacaaaaa ggggtctatg caatgcagcg caaagtaacc atcaatgata ttgctgactt
    10921 agctaaaact tcaaaaacaa ctgtttcttt ctacctcaac ggtcgatttg ataaaatgtc
    10981 tcaggagaca aaaagccgga tcaaggaggc tattgaagcc accaactaca agcctagcat
    11041 tgcagctcgc agtctcaatg ccaaggctac caaattgatc ggtgtggtta tcggtgacat
    11101 caccaatagc ttttccaacc agattgtcaa aggtattgaa agcaaggcgc aagaatttgg
    11161 ttatcagatt atcatcggca acagcaacta tgatccttca cgtgaggacg aattgattga
    11221 aaaaatgctt aacctaggtg tagatggttt tatcattcaa ccaacctcta actttagaaa
    11281 gtattcacgc atcatcgaag tgaaaaaaaa gcgcatggtt ttctttgaca gtcagctcta
    11341 tgagcatcgt acaaactggg tcaagaccaa caattatgac gctgtttatg acaccattca
    11401 gcaatgcatc accaaaggct atcaaagctt tatcatggtt actggcaatc ctaatttgct
    11461 gagcacacgc atcgagcgtg cctctggttt tattgatgtt ttagaggcta accagctcca
    11521 gtatcgtcaa atgatcatcg atgaaaacca aaccagctct caagaaattg ctcagtttct
    11581 acaaggcgca tttgataagg aacgtcacaa tctggtattt gtcccaaact gctgggctct
    11641 gcctaaggtt tttactgcca tgaaggcact aaaggtatca ttgcccgaaa ctggtctagt
    11701 tggctttgat aacatcgaat ggactcgctt gtcatcacca agtattacca ctattatcca
    11761 gcctgcttac gaagaagggg agcaagcaac cagcattttg attgatgata tcgaagggca
    11821 tagcaaggaa gccaagcaac aaatttttga ttgtcaggtt aattggcaag aatcaacctt
    11881 ctaacaggat tttttcgcct tctagacctt aaaaaatcag ccattctaat aacgatgaca
    11941 aagtaacacg aggcttaacg cttgtttgct agcatcagaa aaaacacata aatcagcctg
    12001 aactacccgg ttgatgaaac aataaaccat taagcaacgg tcttattcct cataccaaga
    12061 ggagcaaggc cgttttgacg tttttgacaa tggtcgttat tgtaaacgta acggtagtgt
    12121 attactgaca ggctcttcaa aaaagctgtc gtccttaggt catacgaggc cttcttttac
    12181 aagcgactgc tacttcttca ctactagtgt gatcttttag ccaatttctg agaacatcat
    12241 cagtaaaatc tcgcacctgc caataatggc aagcaagctt ttttgaccag caagttaatc
    12301 atgtatcact tgtgacttca actcttaact gtttgtcctt tcaagtctac tataagagga
    12361 atgaattccc aaaaagattc atcagttgct attatttagg taagagctat aagcacaatg
    12421 gctattatcc tgtgatataa taaaagacat aagggttata aaggagaaat tgtatgagtg
    12481 ataccattac atcaagccct gtggctgctt ctgctgctat tagtgaattg gtaggtgtag
    12541 acaccagtag ggttcaccaa cagtccgttg catttagtgt gaccaagggt attgcaggta
    12601 tggaaaaggg acgtcaggtc tctaatcaac tgctgcaggc tgtcagcgac tttagtcagg
    12661 cagtccttat tcaggctaat aaatttcctc agcttgcggc caaattagag aaaagagacc
    12721 tagaggaagc aacaagatag gggaataagt catgatcaaa gaagaatctg aagaaaaatt
    12781 tcttgcccta acccgacaga tcaatgagct ggagtggcta gaggaggatc ttttgtcgat
    12841 gaaacgacgg catgaacaag cagtctcgga gattcaagca gactgtcagc acctctcttt
    12901 tgcccttgag tccctattga accatatgcc tgaggactaa gctggaaagt acgcagagca
    12961 agaggccaat gaccacttga tcagacaaat ggatcgctat gttgatgagc atctggatca
    13021 cgtgtcaatc tatacgatgg gggttcgtcg tagactagag agggacaaag aagagcttat
    13081 cggtgaaagg agccgtttac gatgggagtg acctacagtg cagcagagtc aaaggccttg
    13141 attcaagcca tgacaaacaa tatccaaata gccaatgaaa taacggacag gttatcaagt
    13201 ggttgcgacc atctcattgc tagtctggat tcgggagagc tacagggagc agcctataca
    13261 gcaggtaggg gactttttac agcgatcatc attccctcta tcaaaaagct acaagcagcg
    13321 attgatgcta tccaagtgga gttgaccacc tatcaaaggg cagatgctca gattgccaga
    13381 tacggaaccc tggatcgtga tcacttaacc gagctgaaga ggctaagaga acggcaagtg
    13441 caagtgatcc aagcacagat tgatgaaaac gaatcgttta tgaagcaggt cagtagtctt
    13501 ttaaccggag actatggcac cctttggtct gatacctcta cactatacca tgccaaaaac
    13561 cagctggaaa tagggattcg agatgttacg accaaattgg aaagccttga atggtttcta
    13621 actcaaacct cagactgctt tagggacagc ttagttattt tgcggttagc cattcagggc
    13681 gcaacacagc tcagtcaggt cttcatgagc agcgacggca gctactcgac tgctggccta
    13741 gatatgagct gggtgactag cctgaagaat caaaagatta gccctgtcaa tgcctcaaag
    13801 tacactcaaa accattatca caacatactg actcagacca ttaaaaccat caaaagcagc
    13861 tctgaaaggc cactacaaaa atcagagcga cttgtagctg cctatgagga ttacctctat
    13921 tttctcaata aaacagcctt tgatgactat tggaaggcga gaagcaatta tgatggagag
    13981 tgagacctta aaaataataa atatgcaaag gaaattgagg aagacctagg gaaaaaatta
    14041 caatcgtcgg gtattaattt tcgtttgatt gtcaacaaga tgggagatga tatcctatca
    14101 gtgaatgtca atgctcccta cctttcacag gtagctggaa gtcaattaag tgctgcaata
    14161 cttgacaaca aacaatttta tgaccttgtc aatacgggtc agcccttgga tttgaagtca
    14221 aggacctatc atggccataa ctattctgtc tggtcaagac agtgggaatc agaattgcca
    14281 ggcgactatg ctggcaacta cctctatggt tatgttggta caggcttttt agatgcttca
    14341 gggacttatt taaaaacggc ggctgagatt gcccaggtct tttctgataa ggatatacca
    14401 aagtggttaa agaacttatc atcaggtcac tatggagaca atgagggtga tactcaaatg
    14461 atccaagcag gtatagatgg ttatatgaaa aggaagaagt caaaatgaag cgaaaaatcc
    14521 tgttattaat gatgttgctg gtaggtgttt tcatcttctc caaacgctat gagctttact
    14581 atttttttca aggaaaagaa tatctaaggc caaatgagag tatagagctt gcggtgagac
    14641 caaagtatga acaaatagaa tattcctctg acctatacct agaaagcgac gaaaaagtgc
    14701 tactgaagct agaaggtcgt gatatatggt ctgaatatat ttatagacgg acagacagct
    14761 atcttagtaa gataggatat cggtattcta taacagaaca ggttattgaa aaatacgatt
    14821 ccactaagga taatggtgta gttattgtag aagctggaca caagggagct actattgatg
    14881 gagatggcct catcgttccc ttgaagggga agagaaaata tagtgtgaca gaagatcatg
    14941 actatagtat caccattacc aacctgtccg atcagccggt tgcttttaga gcaatagtag
    15001 cagataggta gtatgtgcgc atgaactgct ttaggttttt ctgttattga ttttagattt
    15061 ttgttaggca tagaaaagct ccccttatag cttctagtga tggtttgttg ggtcac
//
LOCUS       DARYJX010000049        15097 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYJX010000049 DARYJX010000000
VERSION     DARYJX010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15097
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(220..1320)
                     /locus_tag="TU257_001734"
     CDS             complement(220..1320)
                     /locus_tag="TU257_001734"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0834723.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TU257_001735"
     CDS             complement(1317..1673)
                     /locus_tag="TU257_001735"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL0834724.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TU257_001736"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TU257_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL0834725.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TU257_001737"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TU257_001737"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL0834726.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TU257_001738"
     CDS             complement(5753..6637)
                     /locus_tag="TU257_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0834727.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TU257_001739"
     CDS             complement(6994..10050)
                     /locus_tag="TU257_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL0834728.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEERWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYGSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGRYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TU257_001740"
     CDS             complement(10279..12162)
                     /locus_tag="TU257_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0834729.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TU257_001741"
     CDS             12439..13878
                     /locus_tag="TU257_001741"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL0834730.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TU257_001742"
     CDS             13883..14848
                     /locus_tag="TU257_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0834731.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
BASE COUNT         4306 a         3770 c         2859 g         4162 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta acgtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgccgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaacgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtga
//
LOCUS       DARYJX010000050        14372 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYJX010000050 DARYJX010000000
VERSION     DARYJX010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14372
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(241..489)
                     /locus_tag="TU257_001743"
     CDS             complement(241..489)
                     /locus_tag="TU257_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL0834732.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(543..1463)
                     /locus_tag="TU257_001744"
     CDS             complement(543..1463)
                     /locus_tag="TU257_001744"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL0834733.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            1697..2326
                     /locus_tag="TU257_001745"
     CDS             1697..2326
                     /locus_tag="TU257_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0834734.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            2425..3702
                     /locus_tag="TU257_001746"
     CDS             2425..3702
                     /locus_tag="TU257_001746"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL0834735.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            3716..4378
                     /gene="deoC"
                     /locus_tag="TU257_001747"
     CDS             3716..4378
                     /gene="deoC"
                     /locus_tag="TU257_001747"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL0834736.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            4365..4754
                     /locus_tag="TU257_001748"
     CDS             4365..4754
                     /locus_tag="TU257_001748"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL0834737.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            4845..5897
                     /locus_tag="TU257_001749"
     CDS             4845..5897
                     /locus_tag="TU257_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL0834738.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6024..7556
                     /locus_tag="TU257_001750"
     CDS             6024..7556
                     /locus_tag="TU257_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834739.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            7549..8613
                     /locus_tag="TU257_001751"
     CDS             7549..8613
                     /locus_tag="TU257_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834740.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            8615..9571
                     /locus_tag="TU257_001752"
     CDS             8615..9571
                     /locus_tag="TU257_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834741.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(9609..10865)
                     /locus_tag="TU257_001753"
     CDS             complement(9609..10865)
                     /locus_tag="TU257_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL0834742.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(11385..13100)
                     /locus_tag="TU257_001754"
     CDS             complement(11385..13100)
                     /locus_tag="TU257_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0834743.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
     gene            13336..>14372
                     /locus_tag="TU257_001755"
     CDS             13336..>14372
                     /locus_tag="TU257_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL0834744.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT         4138 a         2559 c         3300 g         4375 t
ORIGIN      
        1 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaggca
      121 aaggcgttac cccagaggga ttgatggatc accatcacta gtttggagcc attagctgtg
      181 ccaaaggttt tctaaagcca aaaagaaaaa actccgattg gagttttcat tggttatgta
      241 ttagctaagc tttgcagcaa gacgtgcttt atcgcggctt gctttatttt tatgaatcaa
      301 accttttgat tgggctttat caatgcttga agaagcagcg cggaaaagct cttcagatgg
      361 gttagcttca aatgccttga tagcagtacg catagctgat ttttgtgctg aatttttttc
      421 gtttgcttta acgttaagct cagcgcgttt aatagctgat ttaatatttg ccaatgtttt
      481 cacctccaaa ttaatctaac tacaccatta tatagaaaat ataggtgttt ggcaagcact
      541 tatcactttt tgagataaat ttcatcaatt ttatggtctg cagctttatg aagaatgagc
      601 tcagctcgat tgcgtgtagg ctcaataaac ttttccagat tttctaggtt aattgttttc
      661 cagacttttt ttgcaaaggc aatggcttca ttttgtggca atgaggtata tctagtgtaa
      721 tagttagccg gatcatgctt agccagctct aaaaggctta agaaccgttc caaataccat
      781 tgctcaatat gatggctatc tgcgtcaata taaattgaaa aatcaaaata atcactcata
      841 tacaatcgat tattctgttg attttgaaaa acattaatcc cttcgatgat gaggaagtca
      901 ggattggtaa aggtttgctg ctgatcagga acgatatcat aaatctcatg cgagtaaaca
      961 ggggctgatg cggtttgtcc tcccttgaca gtatccagaa agtttaacaa tagctccata
     1021 ttataggatt ctgggaagcc ctttcgattc agcatattgt ttttgatcag tgtgctatta
     1081 gggtacaaaa aaccatctgt tgtgaccaac tcaacagtgc tggtcttgtg tgtgcgcgcc
     1141 aaaagaagct gcaataacct gctagttgtg gacttaccga cggcaactga gccagaaatc
     1201 ccaataataa agggtctttg ctgaatatct ttttttagaa agaggctttt agaaaaagac
     1261 aggttttctt gagcgatttt atagacttga atgagatgaa tcaagggaag gtaaacctca
     1321 acaacgtcgt tgatatcaat attatcattc aaactggtga tgctagtaag ctcctcttga
     1381 gtcaataagg gcttgctttt ttgatgtaat tgcttccagg attttctgga aattttttca
     1441 aaagtaataa attcgtttga catagttact cctactaatt ggcagtgctt acattataac
     1501 atgtcaataa aaaaattgaa aaatgtttcg tctgaaattc ttaaaaaaac actgaaaaac
     1561 cctataaaaa tcgaacaatt ttagcctaac aattggctaa tataaagtta atcggtcaat
     1621 gttcggaata tatggttcga taaacgaaaa accaagaaaa acaaacgtct tgtaaaccat
     1681 ttcaaagtgt gatagaatga aaaagcatcg aaaaaagata ggaaaacaca tgacaaaaat
     1741 gtattatgat gaaaatccag atagtgctca tgatatccat caattgacgg tcaatttgtt
     1801 aggacagtcc tttacttttt tgacagattc tggtgttttc tcaaaaagaa tggttgattt
     1861 tggaagtcag gtcctgctca acacattaga ttttcaagaa ggtgatcgtc tgcttgactt
     1921 gggctgcggc tatgggccgc taggacttag cttggcaaag gctcaaggtg ttgaggcgac
     1981 tctagtagat attaatcatc gcgctgttgg cttagctaag cagaatgctg agagtaatca
     2041 ggttgaggcg accatttttc aatcaaacct ctatgacggt gtgacaggga catttgagca
     2101 catcattagt aacccaccta ttagggcagg gaaaaaagtg gttcatgaga ttattgaaaa
     2161 gagtattgat tttttaacta aaggcggtga tttgacagtc gttatccaaa agaagcaggg
     2221 agcaccaagt gctaaagaca aaatggaggc cgtttttggg aatgtgacta ttctcaaaag
     2281 agaaaagggt tactacattt taagaagtat taaggaaagg aattgagctc aagtgtaaaa
     2341 agtggtatta aaaagcatag cggtatttta gtaagagttg ccttctaata tcactatttt
     2401 ctcagagctt ttggtatctt gttgatgaga gcagttgatt taatccaaaa aaagcgtgat
     2461 ggtaaagagc tatctaccga agagatccag tggctgatta atggttatgc caatggtact
     2521 gtgccagatt atcaaatgtc ggcttttgca atggcgatct atttcaaggg aatgtctaca
     2581 cgagaaactc gcgatttgac catgagtatg gttgagacag gtgagcagat tgatttgtca
     2641 gctatagctg gtatcaagac ggacaagcac tcaacaggtg gtgttggtga taaggtgaca
     2701 ctcatcttag ctcctctagt tgctagcttt ggcgttcctg tagcgaaaat gagtggacgc
     2761 ggcttaggcc acaccggtgg aacgcttgat aagctagaat ctatcaaggg ctttcagatt
     2821 ggtcggaccc aagaggaatt tatcaagcag gtacaagaga tcggactttc agttattgga
     2881 caatcagata agcttgtgaa ggcagataag ctgctttatg ctcttcgtga tgtgacggca
     2941 accgttgata ttgttccttt gattgcaagc tctgttatga gtaagaaaat tgctgctggc
     3001 gctgatagta ttttgctaga tgttaccgtt ggtgacggtg cctttatgaa gactattgaa
     3061 gatgctgaga agctgtctag actgatggtt gaccttggta aggaggttgg gcgtcagaca
     3121 gtggctgtca ttacagatat gagtcagcct cttggtcgtg ctatcggtaa tcgcttagag
     3181 gtgctagagg caattgatat catgaaaggc aagggacgca aggatattac tcactttatt
     3241 tgtgagctag ctcagattat gctggagctt gctggtgctc aacactctct tgaggatatt
     3301 caccatcatt tggttggcgg agcagcctta aaaaaattag aagagatggt tgtttatcaa
     3361 ggaggtgatc ttgaggacct ttatcgtcca tcacaggcgg ctgttcaaac agaggttttt
     3421 gcgtcagaag atggttacat cacagcattg cctgctcttg agtttggatt gtttgcaatg
     3481 aggctgggtg ctggtagagc agtcaaaaca gatagtctgg attatgaaac agggattgtc
     3541 tttgacaaga aggttggtga cgctgtcgct aagggagagc gcattgcagt tgtcttttca
     3601 caggaagccc tagacgaaaa aatgcttaca gaatttgaaa aaaatgttaa aataggggcg
     3661 gaacacctag aggctaacga aattatcaaa atcatttcct aaggaggagt ataacatgaa
     3721 tattaacaag tatattgacc acacactact aaaagctgac agcgttcaat cgcagcttga
     3781 ccaattaatt gaggaggcta aagcctatga ctttgctagc gtttgcgtca acccttgctg
     3841 ggtagcctat gctgcaaagg ctttaaaggg aacagatgtt aaggtttgta cagttgttgg
     3901 ttttccttta ggtgcaacta cctcagcaac aaaggccttt gaaacaaagg acgctattga
     3961 aaatggtgct gatgagattg atatggttat caatattggt ctgttaaagc agggtgacta
     4021 ccaagctgtt gaagatgata tgcgtgcagt ggtagaggct agcggagaca aattagtcaa
     4081 ggtgattatc gaggcttgcc tcttgactga tgatgaaaag gttaaggctt gtcagttggc
     4141 ggtaaatgca ggtgttgact ttgtgaagac ctctactggt ttttcaactg gcggtgcaac
     4201 cgtttctgat gtcaagctaa tgcgtcaaac agttggtcca gacattggcg taaaggcagc
     4261 tggtggtgct cgttctctag aggacgcttt agcttttgtc gaagcaggag ctacacgtat
     4321 tggaacttct gcaggggtaa ctattatgaa aggtgaagtt gccaatggag gctactgatt
     4381 tagtttcgtt agccattgaa gctagtaaaa gggcttatgt gccttactca catttcccga
     4441 tcggagctgc tttaaagaca aaggacggaa caatctatac tggcaataat atcgagaatg
     4501 ccagctttgg cttgaccaat tgtggggagc gaacagctat ttttaaggct gtttctgagg
     4561 gacatcagca gcttttagaa attgccattt atggagagac tgatgagcca atctctcctt
     4621 gtggagcctg tcgtcaggtc atggcagaat tttttgaagc cactgctcca gtaacgctaa
     4681 ttgctaagga cggtcgtacc atgcgcacaa ctgttggcga gttacttcct tattcgttta
     4741 cagatttatc gtaatctggc ttaattttgt tatctagcca ttaggcttta tatttacttt
     4801 cggcaattgg tttgctagaa atatttttag gagggttcat attcatgaac aagaaattta
     4861 ttggtgttgg tttagcttct gtagctttat taggtttagt tggttgtggt aatcgtaacg
     4921 cttcaaaggg atctggtgat gctaaaacag atttgaaggt agcagtggtt actgacactg
     4981 gtggtgttga tgataagtca tttaaccaat cagcttggga aggcttgcag gcttggggta
     5041 aggacaatgg actaacaaag ggttcaggct ttgattactt ccaatctaca aacgagtctg
     5101 aatatgcaac taacattgat acagcagttt ctagtggtta tgaggttgtt tatggtatcg
     5161 gatttgcctt gaaggatgca atcagtaagg ctgctgatga caacaacaaa gtacaatttg
     5221 ttatcattga tgatgttatc gaaggcaaag acaatgttgc tagcgtaaca tttgctgata
     5281 acgaagctgc ttaccttgca ggtattgcgg cagctatgac tacaaaaaca aaaacagttg
     5341 gttttgtagg tggtatggaa ggaacagttg ttacacgctt tgaaaaaggc tttgaggcag
     5401 gcgttaagtc tgttgatgac tcaatcaaga tcaaggtgga ctacgctgga tcatttggag
     5461 atgccgctaa gggtaagaca attgcagcag cgcaatacgc agcaggtgct gatgttatct
     5521 atcaggtagc tggtggaaca ggtgcgggtg tcttcaacga agcaagaaca attaacgaaa
     5581 aacgtgacga agctgataag gtttgggtaa ttggtgttga ccgcgaccaa aacgaagaag
     5641 gtaaatatac atctaaggat ggcaaatcat ctaactttgt acttgcatct actataaaag
     5701 gtgttggtaa ggctgttcaa ttgatcaata agcaggcagc agataagaaa ttccctgcag
     5761 gtaaaacaac tgtttatggt ctgaaggacg gtggtgttga gattgccaca acaaatcttt
     5821 ctaaagacgt tatcaaagcc atcgaagaag cgaaagaaaa aattaaatct ggtgacgtaa
     5881 aagttcctga aaagtagtta ctggaaaaga gcgaccttcg tcggtcgccc tttttagagt
     5941 ggaacacctt ttgcttcagt aaaggttgtg acaaatggct ggctttactg aaacaaaaga
     6001 ttaaattgaa aggaaataat cctatggcac agcatgtcat tgaaatgaaa gagattacaa
     6061 aaaaatttgg tgattttgtt gcgaatgacc atattaattt gaatgtcaga aaaggcgaaa
     6121 ttcatgcatt gttaggagag aatggtgcag gtaaatcaac gttaatgaat atgttagctg
     6181 ggcttttaga gccaactagt ggaaacattg tcattaacgg tcagcctgtt gttattgact
     6241 ctccttccaa atctgctaga ttgggtattg gaatggtaca ccagcacttt atgctagtag
     6301 aagcttttac agttgctgag aatatcattt taggaaatga agttgtcaaa aacggttgtc
     6361 ttgatttaaa aaaggccagc aaggacatta aagagctttc tgagaaatat ggtttagctg
     6421 ttgatcctac tgccaagatt gctgatattt ctgtaggggc acagcagcgt gttgaaatct
     6481 taaagacctt atatcgtggt gcagatattc ttatttttga tgagccaaca gctgttttaa
     6541 cgcctgctga aatacaagag ctcatggaaa tcatgcgtaa ccttgttaag gaaggcaaat
     6601 ccattatttt gattactcat aagctggacg aaattagagc agttgctgat agagtcactg
     6661 ttattcgacg tgggaaaagt attcaaacag tagatgtagc aggtgcaacc tctcaggact
     6721 tggctgaaat gatggttggg cgttcagttt cctttacaac agctaaaaag gcagcagagc
     6781 caaaaggggt ggtgctgtcg atcaagaatt tagaggtcga tgaaaatcgt ggaatcccag
     6841 cagtaaaggg gctttctctt gacgttagag ctggtgaaat tgtggggatt gcagggattg
     6901 atggtaatgg tcagtcaggg ctgattcagg ccattacagg cttgagaaag actagatctg
     6961 gtagcattac aatcaaaggt caggaggttg ttcatttaag ctcccgtaaa atcacagagc
     7021 tatcagtggg gcatgtgcct gaggaccgtc atagagatgg cttagtgctg gacctttcct
     7081 tggctgaaaa tactgccctt cagacctatt ataaagagcc actaagtaag aacggtattt
     7141 taaattacaa tacaatcaat gattatgctc gtagactgat gaaggaattt gacgttcgtg
     7201 gtgccaatga attggttcca gctcgtggat tttctggcgg taaccaacaa aaggctatca
     7261 ttgcacgtga ggttgaccgt aaccctgatt tattgattgt cagtcagcca actcgcggct
     7321 tggacgttgg tgctattgag tacattcata agcgtttgat tgaagagcgt gacaaaggca
     7381 aggccatcct cgttgttagc tttgagcttg acgaaatctt gaatttatct gaccgtattg
     7441 cagttattca tgacggtaaa attcaaggca ttgtgttgcc tcaagatacc aataagcaag
     7501 aattgggaat tttgatggct ggtggttcca ttgataagga ggagagtcat gtctaaaaat
     7561 gcacaaaaga ttgctgtgcc aatgatttct atcttgttag gattcttact tggcgctatt
     7621 gtcatgttta tctttggcta tgatccaatt tggggctatg agggcctatt tcaggtagcc
     7681 tttggtagta tcaaaaatat tggtgaaatc ttcagagcga tgggaccact aatcctgatt
     7741 gcacttggtt ttaccgttgc tagccgtgcc ggcttcttta atgtcgggct gtcaggtcaa
     7801 gctttggctg gttggattgc tgcgggctgg tttgctcttg tcaatcctaa tatgcctcgt
     7861 ccgcttttaa ttctgatgac tgtcttgatt ggtatggttg ccggcggaat tgctggcgct
     7921 attccaggta ttttgcgagc ttatcttggt acgagtgaag ttattgttac cattatgatg
     7981 aattatatta ttctgtatgt cggtaacgct atcattcaaa gaggctaccc tgaaagtgtt
     8041 aagcaaagta ttgattcaac catacaggtc agtgataatg ccagctatca aagtcaatgg
     8101 ctgtcagatt taaccaataa ttctcgtatt aatatcggta tcttttttgc gcttattgca
     8161 attgcagtta tttggttctt actaaacaaa acaaccctcg gatttgaaat tcgttcagta
     8221 ggtcttaatc cacatgcttc agaatatgca ggtatgtcct taaagcgtac gattatccta
     8281 tcaatgatca tttcaggtgc tttagcaggc ttgggaggag ttgttgaagg cttgggaacc
     8341 tttgagaatg tttttgtaca gggaagctct ctagcaattg gttttgacgg tatggctgtt
     8401 agcttgcttg ctgccaattc accgattggt atcttcttct catcattcct atttggggtg
     8461 ttgagcatag gtgctcctgg tatgaatatc gcaggaattc caccagaatt ggtaaaagta
     8521 gtgactgcct caattatctt ctttgtaggt gctcactacc ttatcgaacg ctatattatc
     8581 aggcctaaaa aactagtaaa gggaggtaaa taagatgagt ttagttacta tttttgcttt
     8641 attggtttca tcaatgctta tctatgctac acctcttatt tttacaagta ttggtggtac
     8701 cttctcagaa cgagctggtg ttgtcaatgt cggccttgaa ggcattatgg tcatgggggg
     8761 gggttcaggc attgtcttta atcttgaatt tgctcatatc tttggtaaag ctactccctg
     8821 gcttgcagtt ttggtgggag gagttgttgg attgatcttt tcattgatcc atgcgcttgc
     8881 aacgattaac tttagggcag atcacattgt cagtggtaca gtgctaaatc tgctggcacc
     8941 atcgcttgcc attttcttag ttaaggtgat gtacggtaag gggcaaactg ataatatcca
     9001 gcaatcattc ggtaagtttg attttccgat tctctcaaaa attccagttc ttggagatat
     9061 attctttaga aatactagct tagttgggta tttagctgtt gccttttctt tcctagcttg
     9121 gtttgtgctt tacaaaacaa gatttgggtt gcgtttgcgc tctgtaggtg aacaccctca
     9181 agcagctgat acacttggta ttaacgttta cctcatgaaa tattatgggg ttatgatctc
     9241 tggttttctt gggggtattg gtggagctgt ctatgcacaa tccatctctg ttaacttcgc
     9301 agtgacaacc attttaggac ctggatttat tgcccttgcc gctatgattt ttggtaagtg
     9361 gaatccggta ggtgctatgc tatctagctt gttctttgga ttatcacaaa gcttagcagt
     9421 tattggggca caattaccag tattggaaaa aatcccaacg gtttaccttc aaattgcgcc
     9481 atacctattg accatcatca ttttggctgc tttctttgga caagcagtgg ctccaaaggc
     9541 agacggtgtt aattacatca aatcaaaata aaaaaagctc aatgtcaact gtagtgggtg
     9601 actgatagct aagcacgaga gaagacgaat gtcgtcttct cttttgtgat attcaaagcg
     9661 aggtagatac gttttttaaa gttgtcaaag ttccgaaatc cgaaagcatt gcgcttgata
     9721 tctttgataa gtttgttagt ggcttctaac ttagcgttag aataaggcag ttgaatggca
     9781 ttggtgatgt aatcttggta gcgactaaag gtatttagag ctgttttaaa agtctgatta
     9841 agatgtggta gtgtgtcatg aattaaacca aagaaatgct tggcattctt ttcttgcagg
     9901 tgaaaaagga gcagctggta caggtcataa taagagttta actcaggcac tagtgagaag
     9961 atcttattga gacattctct aggagttaag gtttgtctga aggtgcggga atagaaaggc
    10021 ttaagagacc gttttctgct atccttttga ataagcttcc agtagtactt aagagctcta
    10081 tatttaagag acttcttgtc aaatggtttc atgatgtcac tacgtatttg cttgagagct
    10141 ctattgatgt gctggacaat gtgaaaacga tcgagaacga ttttagcctt aggaaataga
    10201 attttaatga gaggaatata acttccagac atatcgacag tgacgacttt caccttgttt
    10261 ctagcctctt tagagtactt aaagaaatga tttcggatgg ttgtttgacg tctattatca
    10321 agaatggtaa tgattttctt agtgttaaaa tcctgagcaa tgaaggctaa tttacctttc
    10381 tgataagaga actcatccca agagagaact tctggcaaat tggcgtaatc ctctcggaaa
    10441 tgatactgct taagcttgcg atagacggta gaagtggaga tagcgagctt agaagcgata
    10501 tgggtgagag cctttctgtt gagtaaaagc tgagcgattt tctgtctcac tatctcagaa
    10561 atttggcaat ttttcttaac cagggtagtt tcagatacag tgacttttcg acaggatttg
    10621 cattgaaacc ttcttttttt caaacgaatg agactaggaa agcctccaat ttcgataaag
    10681 ggaattttag agggcttctg gaagtcgtat ttgatttgtt ttcccgcaca cagtttacat
    10741 ttaggagggt tatagtctag tgtagcgatg acttcaatat gagtatcatg ctggatagct
    10801 ttagtcaagg tgatatgttt gtctttgatt ccaatgagtt gtgtggtatt attgaggtgt
    10861 tccataagat accttctaaa tgatagttta gtcgcttttc atgataagtc ttatgggact
    10921 tttttgatac tcaaaaagcc ctataatctc cacagtagcc ttacccacta cagaaattat
    10981 agagccatct tagaacactg gacttgttcg ctttttaatg aattaaattt agtagatcct
    11041 ttaaaggcat gctatcaagc tttttatcct tgacttttgt ttagcaagtg aagtgttcac
    11101 aaaagctagc taaaacactg agctgacaat gtagagaatg gctcgttttg acaaggttag
    11161 agtgcttttt gctgtatggt ttttaatcca cgcacctgaa aaagaaagga caggacctgt
    11221 gcgagcttac ttgtggttag taggtttcaa ttcatgctcc caaaaaggaa gcaacgcaac
    11281 tctgagaaag gtcttagacc actttcccag tttgcctcac agctaatggt gtaaaacaaa
    11341 tagaccaccc tgtaacaggt ggtcatggtt agatatcagc tcatttaaga gacaaaggcg
    11401 ttgatttcag attcaatatt ggcaattttt tcttcggcaa gcgcaagggt gtcaccaaca
    11461 gttgcgatat aaaatttaat ttttggctct gttcctgatg gtcttacagc aaaccatgaa
    11521 tcatcagcta gggtatattt taagacattg cttggaggag tggttagctg ggtttgacca
    11581 gctttatgag ttgccgtctg actgaggaaa tcctctgtta acacaatatc agtgtgatta
    11641 aactgcgcag gggcatgctt gcggaattta tccataatct gtttgatttc agctgcgcca
    11701 tcaacaccag acagtgtaac agaaatggtt ttttctgcaa agtagccgta ttctttgtaa
    11761 atgtcatcaa taccatcagc aagggttagt ccacgagagc ggtagtaggc agcaatctca
    11821 gccaccaata gcaccgcttg aatagcgtcc ttatcacgta caaatggttt aatgagataa
    11881 ccaaagctct cctcaaagcc aaacatatag gtgtaattgt gcttttcttc aaattcttga
    11941 attttttcag caatgaactt gaagcctgtt aagacattaa acatggttgc cccgtagctc
    12001 tctgcaattt tagtcactaa ttcagtagag acaatggatt tggcaagagc ggcattgtta
    12061 ggtagggttc cagcctgctg atgtgcttct aaaatatact tagcaattaa agcaccaatt
    12121 tggttgcctg ataggttgcg atagctgcca tctgcctgcc gaatttcaac cccaagacgg
    12181 tcagcatctg gatcagtagc aacaagaaca tcagcatcaa cctgacgtcc aagctcctca
    12241 gcaagagtaa atgcctcttg actttcagga ttaggagatt tgacggtaga aaaatctgga
    12301 tctggcttag cctgcacctc aaccacctga acggacttaa agcctgcttg tgccaaggca
    12361 cgacgtgcta gcatttcacc tgttccatga agaggtgtat agacaatttt catgtcacga
    12421 ccatagtcat tgatgaggtc ttggttgata ttgacctttt tgacctcttc taaataagca
    12481 aggtcaacag cttcaccaat aacctcgatg agcccattag ctttggcttt ctctaaatca
    12541 gcaagcctaa tggcaaaggg gttatcaatc gcacgaatgt aatctgttag agcgtcggcg
    12601 tcagctggag gcatttgacc gccgtcagac ccataaacct tatagccgtt gaatggtgca
    12661 gggttgtgac tggcagtaac catgataccg gcaaaagcac ccaaatgtcg cacagcaaag
    12721 gaaagctcag gtgttggccg aaggctttca aaaacgtatg atttaatgcc atgagctgct
    12781 agtacctgtg cagattcaaa ggcaaattct ggagaaaaat gacgagaatc ataggcgata
    12841 gcgacaccgg ccttcttagc agcttctccc tttgactcaa ctaatgctgc caagccctca
    12901 gttgcttggc gaacaacaaa aatattgata cgattcgttc cagcgccaat atagccacgc
    12961 ataccagctg ttccaaattc aagattggtg tagaaggcat cttcctttgt tttttcgtcc
    13021 atgctaagta attcatctct taaataggct ggtagatctg gaatatcaag ccatttttga
    13081 tagttttctg tgtaagtcat agtattctcc tttatatttt taaccgcttt cattatatca
    13141 tgttgaaaag gaaaaatcac ttattttctg taatagcttc caatcatttt ttcacataag
    13201 gatcaatttc cttgcttccc gactttatca cttgttttag tccacacctt actcaacccc
    13261 ttggtagagt aaggtttttt aataaatttt aacgcttttt cttgttgtgt atggttatat
    13321 atgttataat aaactatggc ttttattaaa acaacaacga ataaagaagg taggacgcat
    13381 gtctaccttg tagaagggta tcgtaaagat ggtaaggtca aacagcgtat ccttaaaaaa
    13441 tttggtctct tagatgagct tgaattggaa gaaccaggga ttcttgagcg tcttaagcgc
    13501 gaagctaaag aagatacttt aaataaccct aaggtactcc aggtttccta tgacctcctt
    13561 gcccccatga accaaccgga tcaatcttat ggttggatgg ttttggataa tctcttcgaa
    13621 tctctggggc tcacagcctt tttaaagggt atcaaaacga agtctgagta tgacttagtg
    13681 caagtgctaa agctattagt ttttcagaga attctccgac cagatagtaa acttgccacc
    13741 tatgcctctc aagcagactt atttggccat tgggacatca gcttaaatgc catttatcgc
    13801 tccttgaaca aattgaacac cttgaaagat gatcttcaac atcatcttca caaggtagtg
    13861 agtcagatga tcaaacgtga agccagtctc gttttctacg atgtcaccaa ttattatttt
    13921 gagacagata ttccagataa cgagttggtt tcagaaaatg gagagatact acaagaaggg
    13981 cttcgaagac gtggtccgag taaggaacac cgtccaaaac ccattgtgca attaggactc
    14041 tttagggata ccaacggtat tccgattagc tataaactgt ttcgaggtaa tcaaaccgat
    14101 cctgttacct atcttccagc ggttgaggaa gtcaaaaaac aatttggaat tgagcggtta
    14161 attgtagtcg ccgataaggc gatgaatagt atggctaatg tttcagaaat gctcaagcaa
    14221 gaagatggct ggctcttctc acagaaacat cgcggacgcc gaggagctcc aaaagatatt
    14281 caagaacaca tccttgattc atcggattgg caatttaacc cagaacttac cttcgctaag
    14341 aaatcttata tccgtgaacg gaagttaggg aa
//
LOCUS       DARYJX010000051        13834 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYJX010000051 DARYJX010000000
VERSION     DARYJX010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13834
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(81..1361)
                     /locus_tag="TU257_001756"
     CDS             complement(81..1361)
                     /locus_tag="TU257_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0834745.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU257_001757"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU257_001757"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL0834746.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTRIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TU257_001758"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TU257_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0834747.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TU257_001759"
     CDS             6342..6845
                     /locus_tag="TU257_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL0834748.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TU257_001760"
     CDS             7344..8537
                     /locus_tag="TU257_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0834749.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TU257_001761"
     CDS             complement(8736..9200)
                     /locus_tag="TU257_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834750.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TU257_001762"
     CDS             9468..10316
                     /locus_tag="TU257_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL0834751.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TU257_001763"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TU257_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL0834752.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TU257_001764"
     CDS             11592..12071
                     /locus_tag="TU257_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL0834753.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..12433
                     /locus_tag="TU257_001765"
     CDS             12068..12433
                     /locus_tag="TU257_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL0834754.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            12452..13096
                     /locus_tag="TU257_001766"
     CDS             12452..13096
                     /locus_tag="TU257_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0834755.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(13527..13694)
                     /locus_tag="TU257_001767"
                     /pseudo
     CDS             complement(13527..13694)
                     /locus_tag="TU257_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT         4142 a         3033 c         2643 g         4016 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcag cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat tcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgctttggg tctttttcct tttggaaaag ccatcgaaat
    12241 tggccaagga gcaggcagcc tgctgctcaa tatcatctgg attgtctgct gtggctggag
    12301 cttagcgatc atgcatttga cttctgccct tctcttgtgc ctcacgattg ttggcattcc
    12361 atttgcccgg caatctctaa aattggccaa gattagcctc tttccttttg gagccatcat
    12421 ttatgacatt taattaggaa gcaaaagact tatgaaattg tattttgtca gacatggtaa
    12481 aaccttgtgg aacctagagg gccgttttca gggagctaac ggagattcgc ccttgcttga
    12541 aagctctaag gacgatttgc gccagctagc aagagagctg tgggacattt cttttgatgc
    12601 gatctactcc agcgacctaa aaagagctgt tgatactgct cgcattattg tggacgaagc
    12661 taactgcaag actgatatta gttataccaa gcagctgaga gaatggaacc taggcaccct
    12721 ggaaggaacc aaaatagcaa ctgtatccgc catctacccc agtcagatgt cagcctttta
    12781 tcacaattta gccaaattca agcccagtca atttaaggct gaatcccttt atgaaagcac
    12841 acaaaggctt tatcagctca ttaaaagttt ggaagataag gcctatcagc aggttttaat
    12901 ggtaggacat ggcgcccatt tgacagcttc tattcgtgct cttttaggct ttgagccagg
    12961 tatgcttcgg gcacagggag gactggataa tgccagccta accgttatag aaaccttgga
    13021 tttcaaacac tttcattgtc taaggtggaa tgatacatca tttttacaaa aaaagactac
    13081 tagattaaca ccctagtagc tcttaagcac aaagctccaa gacagctaaa ctgtactcca
    13141 ttggttagag aacacatctc attttttgag ggacgcttta ttagctgtag gaagttatga
    13201 aaagctaaat acacgagagg actaaattgg acaagctcaa aagtttgaca atgtatttca
    13261 aaaaaggatt gaattctgta tcgaacagga ctcagtcctt tttatcattt atcaagccga
    13321 ccaaggcttt caaccacgac aaacgcgcaa aacagttatt tcctgatgat agtagagact
    13381 acagcagata ttttcaatga ttttcttgta gtaacatcta tacaaaacaa tacagctcat
    13441 tgaaatatag gaacattaaa attcagaaag atttcttttc ttgctaaaaa tctttcatcc
    13501 atttcaaact ggttttcatt tgtcctctcc tttttcagtt ctgctttttc tccataagct
    13561 gcacagttga tgtactcctt gcctttaccg tacttcttta caaatgtaaa atttacaact
    13621 tatacttctt ctccttctct ttcaaaactt gagtaaattg attctgctac taaatttgcg
    13681 ttaatattaa tcatttttta tccataattt ttctcctttt ttaatttaaa attcccatta
    13741 aaaaagcgac tggacttttt ccaatcgctg atacttctac tattttattt ttatttcggt
    13801 agaacttcta atccttatca tctatatcct cctt
//
LOCUS       DARYJX010000052        13609 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYJX010000052 DARYJX010000000
VERSION     DARYJX010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13609
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            6..596
                     /locus_tag="TU257_001768"
     CDS             6..596
                     /locus_tag="TU257_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0834756.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TU257_001769"
     CDS             606..2168
                     /locus_tag="TU257_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834757.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TU257_001770"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TU257_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL0834758.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TU257_001771"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TU257_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL0834759.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TU257_001772"
     CDS             4388..5317
                     /locus_tag="TU257_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834760.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TU257_001773"
     CDS             complement(5707..6348)
                     /locus_tag="TU257_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0834761.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TU257_001774"
     CDS             6685..9156
                     /locus_tag="TU257_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL0834762.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..10496)
                     /locus_tag="TU257_001775"
     CDS             complement(9330..10496)
                     /locus_tag="TU257_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0834763.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
     gene            complement(10672..10938)
                     /locus_tag="TU257_001776"
     CDS             complement(10672..10938)
                     /locus_tag="TU257_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834764.1"
                     /translation="MSQEIYSKSEIDLKFENLETKIDSKFDLLMQKMDDGFEKQRLNT
                     EKMLSDFKLNLVTDQQKNKKEFMYWAIGIIIALAGIAFPIWFGK"
     gene            complement(11040..11465)
                     /locus_tag="TU257_001777"
     CDS             complement(11040..11465)
                     /locus_tag="TU257_001777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834765.1"
                     /translation="METEKINNVNILRSNNSRLSGYATSASYPLILPIIVEFELYNIK
                     QSKTYLFQITATKINDRRQNNHIKDLLSLSSNQTTVTISAERHNTFFPYEGYGTVATK
                     LDFSFNIDSPGDYCIALTLLDSEGSLLDKHSNYYIFGEE"
     gene            complement(11531..11857)
                     /locus_tag="TU257_001778"
     CDS             complement(11531..11857)
                     /locus_tag="TU257_001778"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834766.1"
                     /translation="MYFDEFKEYVENNSRAHDYFFERALDYQNAKNARRTPAHRRWKE
                     QKVLKEVETMWTNVVKQLYDNIKLNGKFRKRFMHQEEIDEWVSFMNEHEILESFADSM
                     AEIEFE"
     gene            complement(11870..12157)
                     /locus_tag="TU257_001779"
     CDS             complement(11870..12157)
                     /locus_tag="TU257_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0834767.1"
                     /translation="MYKIEFDPKVKKQLKKLDKTASSKIIRWLYANVDGTSLPRLHGK
                     ALTGDLAGLWRYRIGDYRVICDIQDDKLVILAVHIAHRKQVYKLKLPNNKR"
     gene            complement(12157..12387)
                     /locus_tag="TU257_001780"
     CDS             complement(12157..12387)
                     /locus_tag="TU257_001780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834768.1"
                     /translation="MTTFTLTIDEKNKYIADYFKRNNIDDSQLTFEQLLTVLEDAEDY
                     AAGMAVLMEQKDNPDYKTYTLQEVADELGITL"
     gene            complement(12401..13168)
                     /locus_tag="TU257_001781"
     CDS             complement(12401..13168)
                     /locus_tag="TU257_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0834769.1"
                     /translation="MSERNLRQVDILEKSKPFQKQLGVKMGRSTLSQYVSGKSVPAQR
                     QLYLLSKTLNVSEAWLMGYDVAIERIPDEKRRATTEISNQPEIVSIYNQLEQPRQEKV
                     LSFANEQLEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPR
                     YDYAIGIRGDSMLPKYEQGDMLYIVDRGMSTYNGQLCIVVHNGQTYFKKVYTEEDGLR
                     LVSLNKKYNDIFIDYPPAEDTYIKIYDVVGSFTPVEM"
     gene            13376..13609
                     /locus_tag="TU257_001782"
     CDS             13376..13609
                     /locus_tag="TU257_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL0834770.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
BASE COUNT         3842 a         2638 c         2848 g         4281 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat catattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatca
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatattcc agtactgatc aactgtcaaa tttttgttat aagcaaaatc attgttttct
    10321 attttttgct caatttcagt aagtgcagct ctggcttcct gtagcgtttt taagttgctt
    10381 tttgtagcct ctttcttttt accttttaag taataacccc tacggacgta gtagcgttta
    10441 cctttctttg tatcgtaggt aaagatattt gggtattttg ttttgttgta tttcattctt
    10501 aaatcctttc gttttttgac ttttggacga ggtcgtttga aaggatattg gcatcaccac
    10561 ctttgtgtga tataatttta ggtacaagaa aacgaccttt ttaatggttg tttcttatac
    10621 ggtttcgcct cacgctcaga gtcgccaaac tttgagagcg tggggctttt tttatttccc
    10681 gaaccaaatc ggaaaagcaa tacctgctaa ggcaataata ataccgatag cccaatacat
    10741 aaattctttt ttatttttct gttgatcagt cactagattt agcttgaaat ctgacaacat
    10801 tttttctgta tttaatcgtt gtttttcaaa accatcatcc attttctgca tcaataaatc
    10861 gaatttgcta tcaattttcg tttcaagatt ttcaaacttc aaatctattt ctgatttgct
    10921 ataaatttct tgtgacataa tagattcctc ctgactcttt tctaagtcta ttataccatt
    10981 atttttggca tcaatgttgg aggtttcggg tttatatagt gtaagatatt cactcataat
    11041 tactcttctc caaaaatgta ataatttgag tgcttatcta ataaagatcc ctcgctatcc
    11101 aaaagtgtaa gcgcaatgca atagtcaccc ggactgtcta tgttaaacga gaaatcaagt
    11161 tttgttgcca ctgttccgta tccttcatac ggaaaaaatg tattatgtct ctctgcggag
    11221 atggtgacag tagtctgatt gctggatagt gatagtaagt ctttgatatg attattttgt
    11281 cttctatcgt ttattttagt tgctgttatt tgaaatagat aggttttgct ttgcttaata
    11341 ttatacaatt caaactcaac tataatgggc aatataaggg gataactcgc acttgttgcg
    11401 tatcccgaaa gtcttgagtt attacttcgt aaaatattta cattatttat tttttcagtt
    11461 tccatgctta tctccttaac taattaaaaa ctctaattct tctttgatca acgctccgtt
    11521 agcgacgttc ctactcaaac tctatttcag ccatgctatc tgcgaatgat tccaaaattt
    11581 catgttcgtt catgaaggaa acccactcat caatttcttc ttggtgcatg aaccgtttcc
    11641 tgaacttccc gtttaacttg atgttgtcat aaagttgctt gacaacattg gtccacatag
    11701 tctcaacttc tttgagtacc ttttgctctt tccatcgcct atgagcgggt gttcgcctag
    11761 catttttagc attttgataa tcaagtgccc tttcaaagaa ataatcatga gcacggctat
    11821 tgttttctac atactcttta aattcgtcaa aatacattac tttaaacctc tatcgtttat
    11881 tgtttggcaa tttgagtttg taaacttgct ttctatgggc tatgtgaaca gctaggataa
    11941 caagtttatc atcttgtata tcacagatga ccctataatc tcctatacgg tagcgccata
    12001 atccagctag gtcaccagtt aacgcttttc cgtgcagtct aggtagagaa gtaccgtcca
    12061 cattagcata aagccaacgg ataatttttg aagatgccgt tttatctaat ttttttagct
    12121 gctttttgac tttagggtcg aattctattt tgtacatcat agagtaatac ccaattcgtc
    12181 agctacttct tgaagtgtgt aggttttata gtcgggattg tctttttgtt ccatcaacac
    12241 tgccatacct gccgcatagt cttctgcatc ttctaggaca gtaaggagct gctcgaacgt
    12301 gagctgacta tcatcaatat tatttctctt gaagtagtca gctatgtatt tatttttttc
    12361 atcaatcgta agtgtaaatg ttgtcacaat atctcctcct ttacatttct acgggtgtaa
    12421 aactgccgac aacgtcatag attttgatat aagtatcttc tgctggtggg tagtcaataa
    12481 aaatatcgtt atatttcttg ttgagagata ctaatctaag tccgtcttct tctgtatata
    12541 ctttcttaaa ataggtttgt ccgttgtgaa caacgataca cagttgaccg ttatatgttg
    12601 acatacctct atctacaata tagagcatat ccccttgctc atattttggt agcatgctgt
    12661 ctcctcgaat tccaatagcg tagtcgtagc gaggaggttc ttcgtcagtg tagacagtat
    12721 atgtgtcata ttcatctgct tcaaatccac gaccaaagcc acttgcggct gccgcgtaag
    12781 ttacgccttg aaccgaaaat aattcttcat gcgtagaaac aactttattt tgttcttcca
    12841 attgttcgtt agcgaagctg aggacttttt cttgtctagg ttgttctagt tggttgtaga
    12901 tggacactat ttcaggttga ttagatattt ctgtcgtagc tctacgtttt tcatcaggta
    12961 tgcgctctat ggctacatca tatcccatca gccatgcctc gcttacgtta agggttttag
    13021 ataaaagata gagttgtcgt tgagctggaa cagatttgcc actaacgtat tgcgaaagag
    13081 tacttctgcc catctttacc cccaattgtt tctgaaaagg ttttgatttt tctaaaatat
    13141 caacctgcct taaatttctt tctgacatca gttgttttaa tctatttgaa gtagaactac
    13201 attgcataaa agtagattcc tttcgatgtt tataggttaa ttataaaaca tcttgaacaa
    13261 aagttcaata aaaaaattca aaaaaatgaa ctttgtgtat tgacaaagtt caaaacaaag
    13321 tgtaacataa aagcataaag ttcatgaaca tgaacaaaaa agaaaggagg ttcctatggt
    13381 ttttgattat tcaaaactca gcggaaggat cgttgagaag ttcggcacac agtacaactt
    13441 tgccttggct ttagggctat ctgagcgctc gctatcttta aaacttaata ataaagtaga
    13501 ctggagaagc aaagaaattg cgcaagcttg tcaagagtta gatatcaacg aaaacgatgt
    13561 aggagaatat ttttttaagc aaaatgttca tattcatgaa caaaactaa
//
LOCUS       DARYJX010000053        13116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYJX010000053 DARYJX010000000
VERSION     DARYJX010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..96
                     /locus_tag="TU257_001783"
     CDS             <1..96
                     /locus_tag="TU257_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0834771.1"
                     /translation="ITEYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
     gene            complement(154..1203)
                     /gene="citC"
                     /locus_tag="TU257_001784"
     CDS             complement(154..1203)
                     /gene="citC"
                     /locus_tag="TU257_001784"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL0834772.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1470..2533
                     /locus_tag="TU257_001785"
                     /pseudo
     CDS             1470..2533
                     /locus_tag="TU257_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2619..3503)
                     /gene="citG"
                     /locus_tag="TU257_001786"
     CDS             complement(2619..3503)
                     /gene="citG"
                     /locus_tag="TU257_001786"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL0834773.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3496..4191)
                     /locus_tag="TU257_001787"
     CDS             complement(3496..4191)
                     /locus_tag="TU257_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0834774.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4344..5747)
                     /locus_tag="TU257_001788"
     CDS             complement(4344..5747)
                     /locus_tag="TU257_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL0834775.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            6129..6473
                     /locus_tag="TU257_001789"
     CDS             6129..6473
                     /locus_tag="TU257_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834776.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6491..6886
                     /locus_tag="TU257_001790"
     CDS             6491..6886
                     /locus_tag="TU257_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL0834777.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6936..8057
                     /locus_tag="TU257_001791"
     CDS             6936..8057
                     /locus_tag="TU257_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL0834778.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8239..8547
                     /gene="citD"
                     /locus_tag="TU257_001792"
     CDS             8239..8547
                     /gene="citD"
                     /locus_tag="TU257_001792"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL0834779.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8535..9422
                     /gene="citE"
                     /locus_tag="TU257_001793"
     CDS             8535..9422
                     /gene="citE"
                     /locus_tag="TU257_001793"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL0834780.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9424..10956
                     /gene="citF"
                     /locus_tag="TU257_001794"
     CDS             9424..10956
                     /gene="citF"
                     /locus_tag="TU257_001794"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL0834781.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10949..11509
                     /gene="citX"
                     /locus_tag="TU257_001795"
     CDS             10949..11509
                     /gene="citX"
                     /locus_tag="TU257_001795"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL0834782.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11540..12931
                     /locus_tag="TU257_001796"
     CDS             11540..12931
                     /locus_tag="TU257_001796"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL0834783.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3849 a         2620 c         2894 g         3753 t
ORIGIN      
        1 atcactgaat acatctttta ctacaacaac aaacgcatta aagcaaagct aaaaggactt
       61 agccctgtgc aatacagaac taaatccttt cactaatatg tcgtgtccaa cttttggggg
      121 tcagtacaca gttagagagg gggtagttgt tggttaataa tgcttaaggt ctgttgctgc
      181 tttgatctta gttatcgtgg gctgagcagc ctcgctccta aaaaagtcaa gtgaggtctt
      241 aggaaggagt agctctaaga gagcataatc atcgtccttg atggcctgtc tggcaagaga
      301 ggcgctgatg attttgcctt ctgcaaaggt ttttctaggg ataacctgca catcaatgct
      361 atagcaaggc agctgcttga gcatgacagt gttgtaatgc tgtgtgacca tgctagtagg
      421 ctcttcgcca acataacgac tcttgatttg gagtttttct gcaatgtgac ggaaaatgac
      481 aatatccaat ttagcttgac tatcaataac tgctagctca tctttttgaa aataagcagg
      541 aaaggttgcc tgactaatca tgtaaggtcc actatcgtgg tatatgatat ttgctaggtg
      601 tgcagttcct ttgatgatta attcctttcg gatatggtag gggatcaggc tactgtcttg
      661 actgaccata aagagatgaa cgagctcgtt gtcagcgcag gccttttcaa tcagatgcag
      721 atgaccaagg gtaaatggat tagcatttaa aacgattgct gcggtctttt gaggactgat
      781 ctggggcttt tctagctgtg acaggtagtg ctcaaagccc ctttttttat tttctaaaaa
      841 acaaagagta tcatcaacca ttgcaatgac atgaaagcca agacttagca atagaggggc
      901 agctgctatt ttagtgtaga taaacagatg atgatgccca cgtgagtagg cctcctcaat
      961 cagatgtgag acaatgtgat taagtaagcc ttctccttgg taggcttgat caacagctaa
     1021 gcagcgcagg ctattgccgt acaaagagcc agtagcaata ggctcgcctt gctcgtcaat
     1081 aatagcacag gtataatcta aatgagggtc tcttctaatg tgctgtcttt gtaacaaacg
     1141 atcaattttt gctttttgct gcttgtcaaa gggaaaaata tgctgtatca agtgctgcgt
     1201 catatgctca cctcttatta cgaaattatc ctcttgcctt tattatagca cgctataggg
     1261 cttattctta agcatcttag ctggtttatg aaaagaatgc acaaaaaaga catcaatgac
     1321 ctattgtctc tgatgtcatt atgatatgat taggactttt agataaatga ttaaggtatg
     1381 gaggatttaa gcctgcaaaa ggtggcaata ataattctga cttatgctat aatagagcta
     1441 ttgatattaa gggggataaa ggggctggta tgctttcgat tctaatgact ttatttgttg
     1501 ggacgctggg agggcttgtt gctaagcggc tgagtattcc tgcccctttt atgattggca
     1561 gtatggtagc tgttgcccta gcttctatcc tgacaaagca ggtagaggct attaacccca
     1621 tgaagatttt tgctcagatt attagtggtg cctatattgg ccaaagcgtc agcaaatctg
     1681 acctgcttaa tctgcccaag ctagccaagt ctattattag tctcatgtcc ttgttcacgc
     1741 tgaatatgtt tcttcttggt ggggtatttg tttactgctt tgatcttgat cctgtaacag
     1801 ccttgttgag ctgtttacct ggtggcatta tggacgtttc tcttatggca gttgatatgg
     1861 gagcaaaggc tgatatagtt gcgacattac agtcggctcg actggtcggt atgctcttgt
     1921 ttcttcctgt ttgggtgacg ttttgggtca atcgctttga cccaaaagca aaagctacta
     1981 aaaaaaaaag atagtcaaaa gcgctagctc ccaagataca agaccttcta ggaaagagca
     2041 gctatggaat aatgtccagg ttttaagcat tgctaccatt ggaggtttga tcggtttagg
     2101 gctaaagata cctgtaggcg ctctgattgt ttctttgctt ttttcaacag cactgaaggt
     2161 gcttcggcaa acaagtcaaa tgccaagtac acttcgttat atagcgcagg tttttgctgg
     2221 ctctattatt ggaacaagct ttactcagga tagtttgctt caaatgggac gtctgattgt
     2281 tcctattctt ttacttttga gtagctatct gatcatcaat ctcttttttg gctatatcat
     2341 gtataaaaaa ggtatcttgg atttgcaatc ggcactcttt gcctcatcgc ctgctggtgc
     2401 gacagacatt tcactattgg ctggtgagct tggcggagat atgcctaaaa tcgctggtat
     2461 tcaaatcagt cgaaccctct atactgttgt catcatgccc ttgttggtta aatggctcat
     2521 tagtatatgg taaacagaaa agcccctcag agcataaacc agagatacct agtcattacc
     2581 aaataacata tcaaggatct tgttcaggct tggagctgct ataattgatt ttctaaaaaa
     2641 gcaaagtaga ggcttagcac tagcagatca gcagtccctc caggactgag atgcttttgg
     2701 atcagcttgt cgttgtaggc tgacaaggca gcctttaagt cagcagtgct caaagagctg
     2761 ttgtgcaata gcagcatgtc ctgtttgact tgccgccaag ctttgatgcc tcctcggtga
     2821 atcaggttgc catcttccac aatagacatg aggtaaacca gcagttgcag ttgagcggtc
     2881 tcctgatcag tgctgcgaag gctcttgcgc aaaaaaggca gcgccttgtg agcaattgta
     2941 ggatagccct cgctggcttc tcctctaggg ccctttatac cgtaatctag aaagagcttc
     3001 tcaccatagg tgagctcttt ttttaggtct aagctaccaa aatcagtctc aaggagatga
     3061 gctgttagag gcttgacaag ctgacaaata gccagactat cctcctcagt aaaggctgtt
     3121 acatggtcca agagctgtgg ttgatcggca agatacattc ccgttgcccc aagcagaagt
     3181 gctaaggaaa aattgactcc cttatgggta ttgactccct tagttgcgct gaacatggct
     3241 tgctcagcct caatgcctga ggcacgcaag cgctcaaaga tcagaccagg atcttcctta
     3301 gcatggtaaa aaccaatgtc taaataaatc ttaaaaaagg gggctaaggc cagagcgcta
     3361 tcaacaaagg ttaagaagct catgtcatca tgagccccgt tatcaagctg atccacaagc
     3421 ccaggcttag gagataagga cacttcgtaa agtaaagcct ttagagcaag cctgctaata
     3481 tcatcaaata ccttcttagt catcctgacg cctgctcatt tcctgtagga taaattctag
     3541 tgagctgttg aggtgctcat gcgtaataag ggtgatttgc tcgtggtcac gatttttcat
     3601 gccacgataa atcatccaat gctcagataa agcgcgtttt cgtctttcta gggaagagat
     3661 cgaaattttt ctaaagtaaa caaggtaggt ctgcaattca gtgacaattt cttttaatct
     3721 gaccatctga ctatagctgt aaatcagatt attaaagctg ttgaaattat ctagaattct
     3781 gttgagatcg tcatcttcta taaaggtttc acaatcagcc aacaaatcat gcatgacctg
     3841 aaaatcttcc tctgtcatca aatacatagc ggtgcttgtt gccagtgttt caagcgcttt
     3901 tctgatttca aagatttcac aagcatcttg aatactaaca cccttgacaa taatgccttt
     3961 tttaggaata tgctctacca aatgctcctc tgataacaat cctagagcgt acctgattgg
     4021 tgttctgcta atatttaggg caatggaaaa ttctttttcg ttgatacgac tgccagcagg
     4081 aatttgtctt aaaataatag ttttctttag ggcgttataa aaagctattt tcaaagggat
     4141 attgcgggat aggtcaagat tattctttac tgcttcgata ataggattca tataatctcc
     4201 ttaatgttca tatcatgata ttattatact gaaaatcatt actaatgaaa ataataatta
     4261 gcctcctaaa aggcgaaagc catgctcgtg aaagaacatg gctttcatta gcccacacta
     4321 cagtcctaat aatagctcgt gacctattgt ggaatgtaaa gcggcatttg tcccattgca
     4381 ataatggtta caacaaagat aataaagata ataatcgcgt atttagcagc ttctttttgc
     4441 cattctccca tatcaagccc agtaagacga agaagcaggt aaataaaggc caccaatgga
     4501 ctgagcaaat ggaaggcttg tcccatcaga gaagcaagag ccatcgccat gttgctaaag
     4561 ccatattcag ctccagcctc cgctaagact ggcaaaatac catagtagaa gccatcattt
     4621 gagataaaga aagtaccagg agctgaaatc agggcaataa caagtcccca gaagccagcc
     4681 aattgctttg gaataatcgt tgcaaagctt tgagcaagag cactagccat accagagcct
     4741 tggaaaagtc ccatgaagat accagcagca aaaaccagaa taacaacctg aacagcatca
     4801 ccggcattat caccaatacg ctttgtttgg tcctttagga caggatagtt aacaataagg
     4861 gcaatacagg ttcccactgc aaataaaaga agtggtgcca tagcaatagc cttatagaaa
     4921 gagccagcaa ccagccaagt gattaagccg atggttaaga tagcattaaa ggcaaagttt
     4981 ttaggacgac ggatagaaag cgtatctgga tctgtaatgt ctgttagctt acgcatttcc
     5041 tcttcggtca aatcaacaac accaagtctt gcacgctcct tgcgtcccat gcttggcgca
     5101 acccaacaaa tgacataaag aagagacaaa accataccag gtgcaaggta tccaaggatt
     5161 tcaggtccca cactaagcac agacatggca cgcgcagttg gaccacccca aggaagcagg
     5221 ttcatgatag tgttttgcag gataatcaag acaccaagat tcatgatgcg catgtttaat
     5281 ttcttataga ttggtaaaaa agcagagcag caaatcaagg ttgttgttgt accatcacca
     5341 ttaagtgaaa cagctgctgc aacaattgca gttgccatca agaccttcat cgggtctccc
     5401 ttagcaaagc gaatcatttt ttcagtaatc gggtcaaaca agccagcatc tagcataatg
     5461 gaaaagaaca ggatcgcaaa aagcagcata atacctgtct tagcagtgtt attaataccg
     5521 tacatgatca taggaccaat agctgtcaga tttttagcaa gcccatcctc accaacaaag
     5581 gcaacaaatt tggcgtctga tgtaaaatca gcagagcctg ttaatataac agcaattgtc
     5641 attatcaacg gaatcatgac cagagctgta aaaggggtca tttttttctt catgacgaca
     5701 tacatgaaga taataatcat agcataagct agaactgtta ataacatatt gttatctcct
     5761 ttttgatttt atgacttcag tataaatgaa agcgttcgca aaagaaatac ctccatgtac
     5821 ggaaaaacac aaaaaaaaca ttttgaaagc agatcctgaa aaaataaatg gttacattaa
     5881 tgtttttcaa cagcagttag ttgctcttat cttcagtaat cgcagtgtgt ttcagcattt
     5941 tttaaaatca gtcatattta ttttagttaa ctgtttttat aaaaatggtt aactaaaata
     6001 agaaaatcct tgaaaatgtg aaagcgctct tagaaagaac acaaaaaagc cattccaaaa
     6061 ggatgaggtg gtatataata agcatagaag cttcccattt gtgggcaaac taagaaagga
     6121 ggtagcttat gcagtttttt caaaacatgt ttagacgctc taaaaaagag gcagccacaa
     6181 gccatcaaga cagagaaaat aagcctgaat ttccgttaga tgactgggag ccagtgccta
     6241 gctacattgc tgcagataaa aaggattatc agacagttag tctgattgcc agtgccattg
     6301 cagctggcga gcaagctagc agtcagttta aggtaaaacg aatcctacag cgcaatcctg
     6361 aggccttaac cgtatcctta atagcatcaa gcattgcagc tggtgtttat ccagagagtc
     6421 aatttctggt taggtccatt tatagtaaga aagtaaacgt tagccacaaa tagtaaaagg
     6481 agaaaagatt atgttgcgta agtttaaaat taccattgac ggaaaagagt acctagttga
     6541 aatggaagaa atcggtgctc cctcccaagc cccagtagta cctcctgttc aaccagcagt
     6601 agctccagcc cctgtagccg aaaaaaaggc agcagaagct ccgcaagctc cagcagcacc
     6661 tgtatcagca ggggcagatg caatgccctc acctatgcct ggtattatct taaaggtttt
     6721 agttaatgtt ggtgatgtcg tacatgaaaa tcagcctcta ttgattttag aggctatgaa
     6781 aatggaaaat gagattgtcg cctcaacagc tggtacagtc acagggattc atgttactgc
     6841 aggtcaggtg gtcaaccctg gtgaaggctt aatcaccatt agctaatcct aagtcgtgtc
     6901 ttgatttaaa atgttgtaga aaaggaagta catttgtgga aacattaatt gcaggagtaa
     6961 cctccatcac tattcctcaa atcattatga tgcttatcgg tgctgtctta atgtatctag
     7021 gaataaaaaa agaatacgaa ccaaccttac tagttcccat gggactgggt actattttag
     7081 tcaactttcc cggcacagga gtcttaacac aggttgttaa tggtgttgag caagaagggg
     7141 tctttgatgc cttattcaat tttggaatcg gtacagagct gtttccatta cttattttta
     7201 tcggtattgg tgccatgatt gactttggtc ctttacttca aaatcctttc atgctattat
     7261 tcggtgcggc agctcaattt gggattttct ttgttgtcgt tgtagccgta ttagctggct
     7321 ttgatattaa ggaagcagct tcaattggta tcattggtgc tgctgacggt ccaacatcaa
     7381 tttttgtagc aaaccaattg gcaaaggatt tgctagggcc tatcacagtg gcagcttatt
     7441 cttacatggc tttggttccg atcattcagc cctttgcgat caagctagtt actaccaaaa
     7501 aagagcgtcg tattcgtatg acctataagg ctgagaatgt gtcacaatta acgaagatcc
     7561 tctttcctat tgtgatcaca cttgtagccg gctttattgc tccaatttcg ttaccattgg
     7621 ttggtttttt gatgtttggg aacctgcttc gtgaatgtgg tgtcttggac cgattgtcac
     7681 agaccgctca aaacgaattg gtcaatatca tcagtatttt actaggacta accatctcta
     7741 tcaaaatgca ggccgagctt ttcttgaatg tgcaaaccct gcttattatc atttttggtc
     7801 tgttggcctt tatcatggat tcgattggtg gtgtgatgtt tgccaaattc ttgaatttat
     7861 tccgtaagga aaaaatcaac ccaatgatcg gagctgctgg aatttcagcc tttccaatgt
     7921 caagtcgtgt gattcaaaaa atggccactg atgaggatcc gcagaatttc atcttgatgt
     7981 atgctgtggg tgctaatgta tctggtcaaa tcgcctcagt tattgcaggt ggcttgctgc
     8041 ttgcttactt tagctaagaa aggacgtgct tatgacaatc aatatagacc atttgatcca
     8101 atcctttgag ctaatggcac ttggaatggc aggagtattt gttgtattag gaattctcta
     8161 tattgtagca gaggctctga ttaagctatt tccagtagaa aaataataga atatgatcta
     8221 aacaaggagg tcaatcaaat ggagatcaaa caaattgctg ttgctggttc gcttgaatct
     8281 agcgacatga tgataacaat atcacctaat gatggtcagg gaatcgtttt ggaattggat
     8341 tcaagcgttg aaaaacaatt tggcaatcat atcagagcat taatcaagac aacacttgcc
     8401 aggctgggcg ttgagtcagc aacgatcgaa gctgttgata agggagcctt ggattgtacc
     8461 attcaggcaa gaacaattgc agcagtccat cgtgctgctg gagttgagca ttacaactgg
     8521 aaggagatcg actcatggaa cgcttaagaa gaacgatgat gtttgttccg ggcgctaatg
     8581 cggctatgct aagagatgca cccttgtttg gagcggactc tatcatgttt gatttagagg
     8641 attcagtttc cttaaaagaa aaagacacct ctcgcgccct tgttcatttt gccctaaaaa
     8701 cctttgatta ttcaaatgtt gagacagttg tgcgcgttaa tagcctagac tcttgtggtg
     8761 ctctggatat tgaggcagtt gtgttagcag gtgttgatgt tattcgcttg ccaaagacag
     8821 aaactgccca ggatattatt gatgttgagg cagtcattga gcgtgttgag cgtgacaatg
     8881 ggattgctgt tggtcgtaca cgcatgatgg cagctatcga gtctgcagaa ggggtcttaa
     8941 aagctcgtga gattgcaaag gcctcaaatc gtctcattgg tattgccctc ggcgcagagg
     9001 attatgtgac taatatgaaa acacgtcgct acccagatgg acaagaatta ttctttgccc
     9061 gcagcatgat tcttcacgca gcacgtgctg ctgggattgc agcaattgat accgtttatt
     9121 cagatgtcaa caatacagaa ggcttccaag ctgaggtgcg tcatatcaag caattaggct
     9181 ttgatggtaa atctgtcatc aaccctcgtc agattccatt ggtaaatgag atttatacac
     9241 caaccgaaaa agagattagt cacgccaagc aagtgatctg ggccattcgt gaggctgaaa
     9301 gtaagggatc aggtgtcatt tcattaaatg gaaaaatggt agataagcca atcgtagagc
     9361 gtgcacagcg tgttatcgct ttggcaacag ctgctggggt attaacagag gaggacattt
     9421 agcatggtta aaaataaact tggtcgtgat attcctcagg agtatgctga tcactatgga
     9481 gtatttgaag gagagctagc acgtatcact agctacaatg aatcaagccg ccgcattaag
     9541 cctgtaaagc caggtgacag taaattgctt ggctctattc gtgaagctat tgaaaagaca
     9601 ggcctaaaag atggcatgac catttcattt caccatcatt ttcgtgaggg ggacttcgtc
     9661 atgaatatgg ttcttgatga gatagccagc atgggaatca aagatttagc tattgctcca
     9721 agctctattg ccaatgtgca tgagccatta attgagcaca ttaaaaacgg agtggttaca
     9781 agcattacct catcaggttt acgtgataag gttggggcag ctatttcatc agggattatg
     9841 gaaaagcctg ttgtgattcg ttctcatgga ggacgtgctc gtgcgattgc tagtggtgat
     9901 attcatattg acgttgcctt tttaggagca ccaagctcag atgaatatgg taatgtcaac
     9961 ggtacgattg gtaaggctac ctgcggctca cttggctatg ctatgatcga tgccaagtac
    10021 gcagatcagg tggtggtgct gacagatcac ctagttgatt atcctaacac cccaattagc
    10081 attccgcaaa ctgatgttga ttatgtcgtg acagttgatg ctattggtga tccacaagga
    10141 atcgctaagg gagcaacgcg gttcaccaaa aatcctaagg agctcctaat tgccgaatat
    10201 gccgctaagg ttatcacaca gtcgccttac tttaaaaatg gcttttcctt ccaaacaggt
    10261 acaggaggag cttccttagc agtgactagg ttcatgcgtg aggccatgct tcaagaaaat
    10321 atcaaggcaa gctttgccct tggaggcatt acaaacgcta tggtagaatt gctcgaagaa
    10381 ggattagttg agaaaatcct agatgtacag gattttgatt acccttcagc agtttcgctt
    10441 ggtaaaaatg ctcagcatta cgaaattgat gctaacatgt atgcctcacc actaagcaag
    10501 ggatcggtta tcaatcaatt agacacctgt attttatcag cgcttgaggt tgacactaat
    10561 ttcaatgtta atgtcatgac aggttctgac ggtgttattc gtggggcttc cggagggcat
    10621 tgtgacacag cctttgctgc caaaatgagt ctggtgattt caccccttat ccgcggacgc
    10681 attccaacct ttgtagatga ggtaaataca gtaattacac ctggaacaag cgttgatgtg
    10741 gttgtcacag aaataggtat tgctatcaat ccaaaccgtc cagatttgat agagcatttc
    10801 aaggacttga aggttcctca atttagtatc gaagaattaa aagaaaaggc ttactcgatt
    10861 gttggaacac ctgatcgtat ccaatacggt gataaggttg tagctcttat tgagtatcgt
    10921 gatggcagcc tgattgacgt tgtctacaat gtctaaggaa ttgattttca aggggaaagc
    10981 tgttacccta gctgatatgc taagggcacg cgaggacaga agccttcgtc aaggaaagct
    11041 tttaacagaa ttctcaaacg aaagcctgct ttctgtgacc atgaatattc caggccccat
    11101 taaaacgtca cctgctttac ttgaggtatt tgatagtgtt atcaaggcaa tcctagaaaa
    11161 gctgtctggc aatcagatca gctatcagct tcgtttgctg ccaaaaacgg gttatgaata
    11221 ttaccttgtg acagccttag atagtcaggc attaaagctc aaaatgattg agcttgagac
    11281 tgatttaccg attggcaggc taatggattt ggacgtttta gtgctgacaa atcagctgcc
    11341 aacccctatc agtcgaacag ccttaggctt tcctcctcgc agctgctatc tttgctcaaa
    11401 agaggctaag gcttgtagta gaaatcgcag tcactcggta gcagacatgc agacagccct
    11461 tgtacactta ctccaatcat tttttgacgg aggcaatcag ctcagttaga ctcaacggta
    11521 ttcttataag gagaatgata tgacaaaaat ccgtataaca gaaacagttt tgcgtgatgg
    11581 tcagcaaagt caaattgcta cccgcatgac tacaaaggaa atgattccga ttttagaaac
    11641 actagataat gctggctatc atgccctaga aatgtgggga ggagctacct ttgattcttg
    11701 cctacgtttc ttaaatgaag acccttggga gcgtctaaga accattcgta aagtagtcaa
    11761 gaaaactaaa ttacaaatgc tcctgcgtgg gcaaaatctt ttgggctatc gtaattatgc
    11821 tgacgatgtc gtccgcagct ttatccaaaa atcaattgaa aacggtattg atattgtgcg
    11881 catttttgat gccctaaatg atccacgtaa tctagagaca gctgtttcag caacaaaaga
    11941 attcggtggc catgcacagg ttgctatttc ttacacaaca agtccagttc atactatcga
    12001 ttattttgta gccttagcaa aagcctatca ggctattggt gcagattcga tttgtatcaa
    12061 ggatatggct ggtgtgttaa ccccggagac cggttatcaa ttagtgaagc gtatcaagga
    12121 aagcattgct ctaccacttg aggttcacac gcatgctacc agtggtattt ctgaaatgac
    12181 ctatctcaag gtcgtagagg ctggtgcaga tattattgat actgccatat cctcatttgc
    12241 cggcgggaca agccagccag caacagaatc gatggttatt gctttagagg acttggggat
    12301 tgataccgga gtagacatga caaggctgac aaaaattgcc gagtatttta atactatccg
    12361 agatcactac agggcagagg gcattttaaa tcccaaggtt aaagacactg agcctaagac
    12421 cttgctttat caggttcctg gcggcatgct gtccaatttg ctaagtcagc ttaaggaaca
    12481 gggactctct gacaaatatg aagaggttct ggctgaggtt ccaaaggtta gagctgattt
    12541 aggctacccc ccactggtga ctccgctatc gcaaatggtt ggcacacagg ccttaatgaa
    12601 tgttatttca ggtgaacgct acaaggttgt cccaaacgaa atcaaagact atgtcagagg
    12661 actttatggc caacctcctg cgccactagg tgaaggtatt aaagagaaaa tcattggtga
    12721 tgaagctgtt atcacttgtc gtccagcaga tttgattgag ccacaattgc ccttgcttcg
    12781 tcaagaaatt gcaggctatg cctgctgtga ggaggatgtg ctgagctatg cctctttccc
    12841 tcagcaggca aaggatttcc taggacgcag agaggatccc ttttatgata tcccagttca
    12901 gtacgtcacc gttgatatag caatggatta atcaaaagaa taaaaagcaa gataactaat
    12961 aaaatcaatc tcctaattat tagtcaaagc tacctaccaa taaactcctt aatcagaacc
    13021 acccgtctaa tgaggtgccc ccaaaaggtt agtccaaaac tttaggctcc atgtcaactg
    13081 tagtgggtag ttgacaagct aacatctgga gaggac
//
LOCUS       DARYJX010000054        12296 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYJX010000054 DARYJX010000000
VERSION     DARYJX010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12296
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(262..465)
                     /locus_tag="TU257_001797"
     CDS             complement(262..465)
                     /locus_tag="TU257_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL0834784.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TU257_001798"
     CDS             complement(482..736)
                     /locus_tag="TU257_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0834785.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TU257_001799"
     CDS             complement(1478..1774)
                     /locus_tag="TU257_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0834786.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TU257_001800"
     CDS             complement(1781..2029)
                     /locus_tag="TU257_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL0834787.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TU257_001801"
     CDS             2289..4445
                     /locus_tag="TU257_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL0834788.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TU257_001802"
     CDS             4456..5814
                     /locus_tag="TU257_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL0834789.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TU257_001803"
     CDS             5914..6045
                     /locus_tag="TU257_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0834790.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TU257_001804"
     CDS             complement(6167..7501)
                     /locus_tag="TU257_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0834791.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIAR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TU257_001805"
     CDS             complement(7501..8250)
                     /locus_tag="TU257_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834792.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TU257_001806"
     CDS             complement(8877..9080)
                     /locus_tag="TU257_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL0834793.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TU257_001807"
     CDS             complement(9097..9354)
                     /locus_tag="TU257_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0834794.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU257_001808"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU257_001808"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0834795.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TU257_001809"
     CDS             complement(11039..12007)
                     /locus_tag="TU257_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0834796.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            complement(12147..>12296)
                     /locus_tag="TU257_001810"
     CDS             complement(12147..>12296)
                     /locus_tag="TU257_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0834797.1"
                     /translation="DCDYITGDTVMIVRKNGRIFDYVLPNEEIRDWEVVIEERVEEVM
                     RELDK"
BASE COUNT         4007 a         2785 c         1893 g         3611 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaaat aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctagca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atagataaaa ctcctaaaat tgtggcttta caatgtcgtt ccccgacaat
    12121 tccccgactt ctggacgagg tcttttttat ttgtctaatt ctctcatcac ctcttccact
    12181 ctttcctcta tcacaacctc ccaatctctt atctcctcat tcggcaacac ataatcaaaa
    12241 atccgtccgt ttttgcgcac aatcataact gtgtctcctg tgatatagtc acagtc
//
LOCUS       DARYJX010000055        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYJX010000055 DARYJX010000000
VERSION     DARYJX010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(152..433)
                     /locus_tag="TU257_001811"
     CDS             complement(152..433)
                     /locus_tag="TU257_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL0834798.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TU257_001812"
     CDS             complement(466..1233)
                     /locus_tag="TU257_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL0834799.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TU257_001813"
     CDS             1352..2092
                     /locus_tag="TU257_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL0834800.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TU257_001814"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TU257_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TU257_001815"
     CDS             3072..5315
                     /locus_tag="TU257_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL0834801.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TU257_001816"
     CDS             5428..6489
                     /locus_tag="TU257_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL0834802.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TU257_001817"
     CDS             6567..7172
                     /locus_tag="TU257_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL0834803.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TU257_001818"
     CDS             complement(7423..8637)
                     /locus_tag="TU257_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0834804.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU257_001819"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU257_001819"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL0834805.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TU257_001820"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TU257_001820"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL0834806.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     GNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TU257_001821"
     CDS             10819..11535
                     /locus_tag="TU257_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0834807.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..12157
                     /locus_tag="TU257_001822"
                     /pseudo
     CDS             11627..12157
                     /locus_tag="TU257_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
BASE COUNT         3303 a         2348 c         2831 g         3675 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacggta atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatt aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYJX010000056        10977 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYJX010000056 DARYJX010000000
VERSION     DARYJX010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10977
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(32..1213)
                     /locus_tag="TU257_001823"
     CDS             complement(32..1213)
                     /locus_tag="TU257_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0834808.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TU257_001824"
     CDS             complement(1297..2532)
                     /locus_tag="TU257_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0834809.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TU257_001825"
     CDS             complement(2854..4092)
                     /locus_tag="TU257_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0834810.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TU257_001826"
     CDS             4400..6376
                     /locus_tag="TU257_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0834811.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TU257_001827"
     CDS             6440..7939
                     /locus_tag="TU257_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834812.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TU257_001828"
     CDS             7939..8865
                     /locus_tag="TU257_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834813.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TU257_001829"
     CDS             8874..9944
                     /locus_tag="TU257_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834814.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TU257_001830"
     CDS             9937..10860
                     /locus_tag="TU257_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834815.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3249 a         2138 c         2281 g         3309 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagtat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctattta
//
LOCUS       DARYJX010000057        10564 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYJX010000057 DARYJX010000000
VERSION     DARYJX010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10564
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TU257_001831"
     CDS             complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TU257_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL0834816.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1719..2432)
                     /locus_tag="TU257_001832"
     CDS             complement(1719..2432)
                     /locus_tag="TU257_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL0834817.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2453..3100)
                     /locus_tag="TU257_001833"
     CDS             complement(2453..3100)
                     /locus_tag="TU257_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0834818.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TU257_001834"
     CDS             complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TU257_001834"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL0834819.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TU257_001835"
     CDS             complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TU257_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL0834820.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6539..7321)
                     /locus_tag="TU257_001836"
     CDS             complement(6539..7321)
                     /locus_tag="TU257_001836"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL0834821.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TU257_001837"
     CDS             complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TU257_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL0834822.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8749..9381)
                     /locus_tag="TU257_001838"
                     /pseudo
     CDS             complement(8749..9381)
                     /locus_tag="TU257_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9383..10150)
                     /locus_tag="TU257_001839"
     CDS             complement(9383..10150)
                     /locus_tag="TU257_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL0834823.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQDIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10432..10564)
                     /locus_tag="TU257_001840"
                     /pseudo
     CDS             complement(10432..10564)
                     /locus_tag="TU257_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3119 a         2382 c         1936 g         3127 t
ORIGIN      
        1 gattataccg ttaaataagc tgccagatca gctaaggcac gtttagcgat agcttcatag
       61 cgttcctttt tatctctgat acgaggtccg tcaagctctt taataatacc aaaattgaca
      121 ttcattggtt gaaaatgctt gctgtccgcg tgtgtaatat aataaggcag gctgccaatt
      181 gctgttgtat ttggaaaaac aagtggctct tcttccttga atagccgagc agcattaatg
      241 ccagccacaa gtccagaagc tgctgactcg acatagccct ccacaccggt catctgacct
      301 gcaaagaaaa gcctgtgatt agcgcgtgat tggaagcctt gtgtcagaag ctttggtgaa
      361 tccatatagg aattacggtg catcacaccg taacgcacaa actcagcatg ctcaaggcct
      421 ggaatcattt ggaaaacccg cttttgctct ccccatttta aatgtgtctg aaagcccacg
      481 atattataaa ggctgcctgc agcattatcc tgacgcagct gcacaacagc atagggcgtc
      541 ttgaaatcac cgtcacgtgg tcccttgtaa tcatctggat attccaagcc aaccggcttc
      601 attggaccat aaagcatagt cttaatccca cgctttgcca taacctcaat tggcatacag
      661 ccttcaaaat acttttcctt ttcaaaagca tttaaaggag cttcctctgc tgttgtcaaa
      721 gcctcgtgaa aggccataaa ctcttccttg gtcattggac agttcagata agcagcttct
      781 cccttatcat atcgcgattt taaataaacc ctatccatgt taatggttga cttatcgaca
      841 attggagctg ctgcgtcgta aaaataaaag ccagcaccac catttaaggc atgtattttt
      901 tcagcaaggc tgtcactggt caaggggcca gttgcaatta ctgtaatagc atcgctagga
      961 atgtcaataa cctcctcacg aatgatttca atcagagggt gattttcaag ctcagctgta
     1021 acagccttgg catagccttc gcgatctaca gccattgctc ctccggcagg gacacgatgg
     1081 gcttcgccag cacgcataat aatcgaatcc agacgacgca gctcttcctt taaaagccct
     1141 actgcgttgg ttaagctgtc accacgaaaa gagttggagc aaaccaattc tgcaaaatgg
     1201 gtggttttgt gttgcggtgt tgccttgaca ccacgcatct catatagctt aacaggaata
     1261 ccacgcttag caatttgata agctgcctct gatccagcta gaccagcacc aataacatta
     1321 atataagatt gagacaatag accaatacct ctttggggac ttatccatca ctgattgccc
     1381 cgcaactctt tctttcaagt aattaccctg cctattataa cagaaataag agcaaagcaa
     1441 aagaaggagc tgaacagcct cagtctttta tataaaggag ataagcccgt acctgcacgc
     1501 tctccacaaa gctagctgct tcaagcattt tagctttcgc ccaataccag ctatccacat
     1561 atcttgttca ctgcagtagt tactggaagg ctttttaagg cttatttttc aaaatctagc
     1621 caaaaatatt tcaccggacc tcatcatctt gctggtagca gctaaacaag ccttttccag
     1681 taaaaaaaaa gcaagcgaaa gcctgccctt gttcttgttt agaaaaaaca catccatgct
     1741 gcgataaaga cacttaagac actaaacagc gatccaatca aataatattc agcaaaggct
     1801 gggctttcag agattttatt gtagcgagca atagacttag cggtaagcac cagtccgatt
     1861 gaagcaaatt gtcccaacac catacaaacg cccataacaa tacgctctaa attaccaata
     1921 gccgcacccg cccctacaat ggtatccatt ggtttatcac tagctggctg gaatttattg
     1981 aagcagagct taaagataat attgacaggc ttggtgatca aaaccataaa aagcactaac
     2041 aataactgcc gagcatgtaa ccaatcaggg atctcagcct gattaacacg agcgactaaa
     2101 gccagaataa tgaaaagatg caagagctgg tccaacacaa agacccacga ccgatcaagc
     2161 ttaatgatac gagcccattt tggcttaaaa taatcaataa ccgcatggct actaaaaata
     2221 aggatcgctg ttagccaaag cttaggtata cacatcacca ctagaaacaa tggagcagct
     2281 acccctaata agtgcagccc cagataagca agctgctcct ccttcttatc agcaataacc
     2341 tgactctgaa ggtgataatc tgataaaaaa tgacaaatca ctagcagcac taaaatagga
     2401 tgctgataaa ggtaatcaga taagccctgc ataggtggct cctttcctct ttttattctt
     2461 gtaggtaggt caaagctgca tggcgacttc taagataaac ctttacactg ctgcttttta
     2521 agcgctttga caaggcactt gattggaggt ccaatgtatc gccaatgagc tgttggtcaa
     2581 attgttcttc atagatccct aagtctaaaa gcgcatgaaa cacctctaat tgactagcac
     2641 gccagctagc ttttatcgcc tcaccagctg ctaaaaggct attgagcacc agatccttgt
     2701 gctccttatc agtccgtata gctacctggg tattgccata atcatttttt tgatgaatgt
     2761 aatgaatagc ctctctggca cgccaatagg ctggaccgtc agcaccaata ctaatatcag
     2821 ggttaatatc agtcaaaata gtcccctgtc caataccaaa cctaacaggg tagcctgtca
     2881 tggcttgatt aattaaatca atgagttgaa aaacaggcgc atcattagtc aacaagcctt
     2941 gaaattcatc acccagagtc acagataagt tagagacgat ataggaagaa aaatcatggt
     3001 tgagctgatc cagacaggcc tttaaggact cttgcaccaa agaacgcgac tgaatttgct
     3061 tagaatggac caaatcccca ataacagcga tatatagcat gattttccct ccttttatga
     3121 cttccattat aacagacaaa aaccaaaaag tccattataa tggaaaatca tctatatttc
     3181 cgttataatg gacctctgct aaaatagttc aaacctactt tacaatctct tctttatagt
     3241 cacagacttc attgctacac acaacctgct tacctccacg aatttttttc tcaacaaggt
     3301 aatcgcctga cttcggacaa gaccgtccta ccggcaaatc ccacgaggta aagtcacact
     3361 cagggtagcg gtcgcagcca tagaaaatac ggttacgctt tgttttgcgc tcaatgactt
     3421 ggccttgctg acaagctgga caagaaactc caatttcctt tgtgatggcc tttgtatgat
     3481 ggcactcagg aaagttacta caagcataaa acttgccaaa tctacccagc ttaacaacca
     3541 tcgggtggcc gcacagctca caatcaaaac cagccggctc gtccttgatt tgaatttttt
     3601 cgatctccgt ttcagccttg gttaactcct taacaaatgg cttgtagaat tggtcaatca
     3661 cattctgcca ggcttctttg ccgatctcta tctgatcaag cttatcttcc atatcagctg
     3721 taaatttgac atcaacaata tcagggaaga attccacaat caattgatta acaatttcgc
     3781 ctaattccgt cggctcaaag cgtttagcag ccagcttaac ataataacga cgctgaatca
     3841 catcgagtgt tggagcatag gttgatggcc ttccaacacc gttttcttcc agtgttttaa
     3901 tcaggcttgc ttctgaataa cgagctggcg gttgagtaaa gtgctgttca ggtgttaagg
     3961 taaccttttt aaccacttct ccttctgtca tttcaggaag catcttgctt ttatcagaat
     4021 cattgtaaac agccatataa ccgtcaaatt tcatctgact gccattggca acaaaaagga
     4081 cactattttg ctctaggtta accttaacag tatcaaacac agcagctgtc atctgactag
     4141 cgacaaagcg gttccaaatc aaggtataga gctttagctg atccttatct aaaaatttag
     4201 caatagcctc tggcgtatgg ttcacattag atggtcgaat agcctcatga gcgtcttgag
     4261 caccagtagc atttttaact cgattgccat gcttagagta ctgactaccg aaacgttcaa
     4321 caataaagcc tgcggcatca ttttgagcaa ctgggctgat acgagtagag tccgtacgca
     4381 tgtaagtaat taacccttgt gttccattag gaccaagact aatcccctca taaagctgct
     4441 gagcaaccat cattgtttta cgagtccgaa agttaatctt attggctgcg tcctgctgca
     4501 atgaggaggt tgtataaggt aaaggagcat gacgcctgcg ttcttttttc tcaaccttac
     4561 taaccataaa atcatcgcta cttaatcgag acaaaacaag cttaacatca tcattggtat
     4621 tgagcttcat ctttttgcca ttgaggccgt aaaagcttgc ttggaatttt tttgtccctt
     4681 ttttaaagag accatcaatt gaccaatatt cttcaggaac aaaggcctta atctcatgct
     4741 ctctgtcaat gattagcttt agagcaaccg attgcacgcg ccctgctgaa agcccctttt
     4801 taaccttttt ccagagaatt ggcgaaatgg aataaccaac aatacgatcc agtacacgac
     4861 gtgcctgctg tgagtcaacc aaatccatat caatttttct tgggccttca aaagcttctt
     4921 tgacggcatc ctttgtgatt tcattgaaaa cgacacgatt gttatcatca ggatcaagtc
     4981 ccaaaatatg tgataaatgc catgaaatgg cctctccctc acgatccggg tcacttgcta
     5041 gataaacctt tttagcattc tttgcttctt tttttaaggc attaatcagc ggacccttac
     5101 cacgaatatt aatatactgt ggctcataat gattgtcaaa atcaatagac attgatgatt
     5161 ttttcaaatc acgaatatga ccaaccgagg caacgacctt atactgacgt cccaaatatt
     5221 tttcgatggt tttagcctta gcaggtgatt caacaatgac tagatttttt ttagcagctg
     5281 ctgatttttt ctttgtagca gatcttttcg tctcttgttt tgacttagtt gctgtttttg
     5341 ttaccaattg acacacttcc tataacagtt atggttaaag cttctagcat aatatcccat
     5401 tttttaagaa ctgtcaacaa aaaattttct ataaatagga agaaaagtta agaatagtgg
     5461 tattctgaaa gaatgtctct gccatgagtg acacagctgg caccatcttt gatcagcttc
     5521 aaacagcccg ccgatgtccc attaagaata ttgtcaggta cgacaaaaat atcacgtccc
     5581 tcttccatag ctagctgaca ggtaatcaaa gagccagagc gctgcttagc ctcaacaaca
     5641 aggacacctc gactaagacc tgcgataata cggtttcttt cagggaaatg ataagacaag
     5701 gcggcctctc cagccccata ttcactgagc acgagatgac gctgagataa aaactcctgt
     5761 agctggtgat tttcctttgg atagtagcga tctaggccag tcccgataac agctatggtt
     5821 tgcccacctg ctttcaagca agcgagatga gcactggtat caatacctct agcaagcccg
     5881 ctgacaatga caaagtgatt cttaagctct ttgatgattt tgtaaacaga ccgcgtccca
     5941 atttcactgg attctctaga gccaacgact gccagcttag gcttttctaa caggcttaaa
     6001 tcaccttgat aaaagagtaa aacaggagga ttatagattt ccctcagggc caatgggtat
     6061 tgcttatcta ggatagataa gctcggaaac tggttgaatt ccttttttaa caaggcgaca
     6121 tttaattgct tgtaggtctc aataaataaa actggatttt tgcagcaaga aaccactgcc
     6181 atatctctaa gggatagaga cttgttatta cgctgctggt agtcaatcag gttaagaata
     6241 tttaaattag ttagcccagc cttttttaat ttataaagtt caaaattatt catcactgta
     6301 cctctctaat gatttattcg taaaaaaatt aaaaaagctc tgactaaaca aagctttttg
     6361 caaactcttg aggagctgta caggattcca gcaaaaaaat cgaggcctcc tagcctttgt
     6421 atgagcattg tagggcagct catcacatag cattccattg aaaaatacca gaattgtaga
     6481 tccacctagt ggctatcgtt tttgctttcg gcagctacct tttctcaaaa tgagattttt
     6541 agcgtaagat cattgatttt atcggctcaa agctttgccg atgaattggt gtgacaccat
     6601 actggtgcaa tccctgcagg tgctccttgg tcccatagcc ggcattttta gcaaagccat
     6661 agcctggaaa ggccttatcg taatcaagca tcaatcgatc tctggtaacc ttagccacaa
     6721 tagaggctgc agcgattgac atagagctcg catcgccttt tataatagcc tgttgaggaa
     6781 tagaaacctc tagtgtcatg gcatcaatga gcaggtaatc aggcttactc acagagccct
     6841 ccagctgatt aatggcagct gtcattgcta attttgttgc ttcatagata ttaacccggt
     6901 caatggtatg gttgtcaata attccaagac cgattcccaa cgctttcttt tgaatggctt
     6961 ggtaaattgc ttcatgctta gctttaggaa tttttttaga atcatttagc cccttaatgg
     7021 tgcagccctt tggcagtata acacaggctg ctacaactgg tccagccaga ggacctcgac
     7081 caacctcatc tataccagca atcgcttgaa agcctttttg gtaaagcgcc tgttcatacg
     7141 tcaacatcgc ctcaagccgg gcttcctctt ttaagatagc ctctaaagcc ctttttctgc
     7201 tagatacagc cttttgaacg ccaagccgct tatccgcctt tagctcttca aaaaatggat
     7261 cagaaagact agaaacagct tctagacgag ctttaatgtc tttaatagtc attgctgtca
     7321 tcatcaccaa cctgatctaa ggtgtactga ccaagtcttc catcacgaat atccttgatg
     7381 aataagctgt aaaaacgatc atagtcttcc ttaaagccaa gctgacgtgt caaggacatg
     7441 atgatttctg gagcgtcagc ctctagatca atagccttaa aacgctttaa taggcgatta
     7501 ggataatact tcttaaaata attcaatcca aaaatcgtga cctcgtccat tggcaacagc
     7561 tgatccttaa tagcccctgt cagggctaat tttaacccaa ccaattcgtc ttcaaacttt
     7621 ggccataaga tacccggagt atccaatatc tctagttctt tattggattt tagccattgc
     7681 tgtcccttgg tcactcctgg cttattgcct actgtggcaa ttttttttcc cgccaagcga
     7741 ttcatcaggg ttgatttgcc agcatttgga atgccaataa tcatggttcg tagcgtttct
     7801 ttttgaatgc ctcgttctct taagcgacgt agtttatctg ccatcaattc cttagcagcc
     7861 tcggtgaccc ttttgaccgt agcctgttcc ttagcattga tagctaatgt cttaatccct
     7921 tgcttctcat aatattgttg ccatttctta gtatgcgtgt tatctgctag atcagcctta
     7981 ttaagaagca ttagcttggg cttatctcca acaattttgg tcagcatagg attttgactt
     8041 gataaaggta gcctagcgtc tactaaaatc gtcacaaaat caacatgctt aatattttcc
     8101 tgtacctgtc tccttgcctt ggacatgtgt ccaggaaacc attgaatcgt agccatgtgt
     8161 gtaaaatcct ttcgtatcaa gggtttttag cccctcgtct tttaaaaatc atgcgagtca
     8221 ccaaaaaatc accaaatatt aagcattatc tccagaccaa gcgatataat tgcaacttgt
     8281 tttggttatt tttaatgcca acaatatcaa atgatttcta atggtatctg gcttatagct
     8341 attctctgct gaatagattg cctcttcaat tttaccctgt aatctcgctc agcctgtctc
     8401 ctgaccttgc ttttacatat gaaactgtaa tattttccat tttaccagtt atatgataaa
     8461 gaaaatcaaa atagtcgtag tagaataaat tactttaaac tattatagca cgatttccct
     8521 tattttactg ctaaattatc ctttgtaaaa gaagatatta atcgttataa agaccaaaaa
     8581 agagaagacc aaaatgatcc cctctagtct tcttttcggc atattttacc gttatttggc
     8641 caactttcca ctaatgtgag taaaattgta ttctaagcaa gctttaccta ttaacttagg
     8701 agaaaacata atctctatag ctaaaaatac caaaaaaatt atgaatcatt atcgcaaact
     8761 atccatagtg atcacttcat cagccatttc ccatattgct ggattatgag ttgctacgat
     8821 gattaatctg ttagcgtcac gaagagacag tacaatctcc ataatcaact tggacgtggt
     8881 tggatctatt gaagccgttg gttcatctgc caaaataaat ggcggatttt ttaagatgat
     8941 ctttgctaag gcaactcgtt gtgactaacc cccagatagc tcaaaaatgc gtttatctag
     9001 gttcagatag gataaaccta cacgttctaa ggcctgtttc tgtctcatcg tttgctcaga
     9061 tttattcaat ttttgaccaa tgagaccaag tttgaggttt tcttcaatcg tttgattttc
     9121 aatcaaacca aaattttgga ataggtaacc caattcatga cggaaaaaat cactagattt
     9181 atagctggct aagtctttgt ctcggtaaaa aatagtccca tgataaggtt ctaatttccc
     9241 catcatgttc atcaaggttg ttttcccgct accgcttgaa ccaatcaaag catagacttt
     9301 tccaacctca aatgtcattg aaagattaga aaatagctct cgttctccaa aagatttact
     9361 cacttgttta agttcaatca tgttaacctc ctttcaaaac aagcatggac atcttgtttt
     9421 ctttctgcat ttgaacatgt aattgtaaaa gagataggcc agtgaagagc aacaatacta
     9481 agaaagcaat cactatctct acttgaagga atacactcgc aacaaatccg agtaaaaaga
     9541 cacccaattg agccaggagg taattccgat ggatttctaa aaatcttagt ccagcaatac
     9601 gtttgatgac aatggcacgt ctaaattctt caaagtagag cctattcatg gtgttaaaca
     9661 acaagattga ggttgctatc ccaagcacag ctcccgcaag cattatccaa cgttccctct
     9721 ggatattatt caacaatgtg atgtagttct ggtatcctga ttgcatttct gagacccaat
     9781 tttcaatgtc ctgtctctgg ataagctcct gggcatcgga caactgatta aagaggacat
     9841 aattctgtac cgcgtcaaac caaaacatga cggactgagg tccagttgac tggggtgtta
     9901 cgacaatgat aatcggatct ttcagaaact gttgatagga aataggtgtc gtattataca
     9961 caaaacggtc ttggcctgat tccaaataag ccaccgtcgc aatcatttgc tgtcgaccat
    10021 cttgactaga catgcgacta gttaagtcgt cttcaaaaac agatttgtaa tgttcttcct
    10081 ctgaacggag atgctcaggc aagagcaaga caaattcccc tactgcgagg tgattcagtt
    10141 tttgttcaat agccgtatct acagggatgt tttgacgctc caagtattgc ggtgtgacaa
    10201 taaggacatt gccatttggg ctgtaatctt gccattctgt agaagttgtc aagtttttgg
    10261 aaaagtctta gcctttgtta tcaatacttg agtagcacct atgtttttca gattagcttg
    10321 ctcttgtaac tgttctgagc tattaaatgc tgtcatttca acggtgatat tttcagttga
    10381 ttctgcctgc ttgttatctt cttttgttgg agattctgga cgtttctcaa aataaaaata
    10441 attataaagc tgttgagccg ttactcctcc accagcccag ccagcaacag gttgaccatt
    10501 cttcagatat agtattgttg gtgttcctgg gattccaact gttttaaata aaaactcctg
    10561 agct
//
LOCUS       DARYJX010000058         9798 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYJX010000058 DARYJX010000000
VERSION     DARYJX010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9798
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU257_001841"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU257_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL0834824.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TU257_001842"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TU257_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TU257_001843"
     CDS             complement(5931..7601)
                     /locus_tag="TU257_001843"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL0834825.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TU257_001844"
     CDS             7799..8491
                     /locus_tag="TU257_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL0834826.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TU257_001845"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TU257_001845"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL0834827.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TU257_001846"
     CDS             9086..9658
                     /locus_tag="TU257_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0834828.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         2864 a         2184 c         1842 g         2908 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt gctctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatg
//
LOCUS       DARYJX010000059         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYJX010000059 DARYJX010000000
VERSION     DARYJX010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            101..1027
                     /locus_tag="TU257_001847"
     CDS             101..1027
                     /locus_tag="TU257_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0834829.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TU257_001848"
     CDS             1135..2421
                     /locus_tag="TU257_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0834830.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TU257_001849"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TU257_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TU257_001850"
     CDS             2977..3189
                     /locus_tag="TU257_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL0834831.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TU257_001851"
     CDS             complement(4085..4225)
                     /locus_tag="TU257_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834832.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU257_001852"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU257_001852"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL0834833.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TU257_001853"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TU257_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TU257_001854"
     CDS             8213..9118
                     /locus_tag="TU257_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0834834.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYJX010000060         9073 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYJX010000060 DARYJX010000000
VERSION     DARYJX010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9073
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1134
                     /locus_tag="TU257_001855"
     CDS             <1..1134
                     /locus_tag="TU257_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL0834835.1"
                     /translation="NEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASY
                     AYKKAMGGRSGTINGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGE
                     HPRAIARDLAKQFNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRLDDRT
                     TEICRKIAKENKRKLLSELKPGINAAPYHFSCRTTLIPDEDELSIEVEPIDDKSTKYF
                     KDVTSDWIDGNGHKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGL
                     QVDMVPRVNSPEHINTPDYLVDGVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDIT
                     KTPLSFEEIMGQLEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            1165..1353
                     /locus_tag="TU257_001856"
     CDS             1165..1353
                     /locus_tag="TU257_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834836.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            1356..1622
                     /locus_tag="TU257_001857"
     CDS             1356..1622
                     /locus_tag="TU257_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834837.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            1778..2347
                     /locus_tag="TU257_001858"
     CDS             1778..2347
                     /locus_tag="TU257_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0834838.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKTNIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            2360..3247
                     /locus_tag="TU257_001859"
     CDS             2360..3247
                     /locus_tag="TU257_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0834839.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            3259..3615
                     /locus_tag="TU257_001860"
     CDS             3259..3615
                     /locus_tag="TU257_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0834840.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            3626..3904
                     /locus_tag="TU257_001861"
     CDS             3626..3904
                     /locus_tag="TU257_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834841.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            3901..4245
                     /locus_tag="TU257_001862"
     CDS             3901..4245
                     /locus_tag="TU257_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0834842.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQQLLHYRVVSPALYSVYIELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            4249..4608
                     /locus_tag="TU257_001863"
     CDS             4249..4608
                     /locus_tag="TU257_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834843.1"
                     /translation="MDYSPETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            4620..5219
                     /locus_tag="TU257_001864"
     CDS             4620..5219
                     /locus_tag="TU257_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL0834844.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            5273..5728
                     /locus_tag="TU257_001865"
     CDS             5273..5728
                     /locus_tag="TU257_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834845.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            5803..6036
                     /locus_tag="TU257_001866"
     CDS             5803..6036
                     /locus_tag="TU257_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834846.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            6051..>9073
                     /locus_tag="TU257_001867"
     CDS             6051..>9073
                     /locus_tag="TU257_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0834847.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPHPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     STVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHALTGAIGGAVSRVDTMNRFPKTMALFGYSAEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWAVMNPASAISTIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQIEQLLNTAVTKGPGIIQ
                     GLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQLITSLVQGIGQNATNLI
                     SSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIPLIIQQAQQIIDSFGNSL
                     QANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAGIQLVAQLAVALIKGLPQ
                     IISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     VMAMNVGMQTTAMANQANTDTTSMLNSISQNTELA"
BASE COUNT         2922 a         1609 c         2042 g         2500 t
ORIGIN      
        1 aatgagcagt atgtatcagc aagagctaca aggatggatg cattaaatct tgaacttgtt
       61 tatcgcgcag ggatactaaa aggtgtactt gattcagcat ttgaaaatca tttaaaaaaa
      121 gctgcctcat atgcttataa aaaagcaatg ggtggacggt cagggacaat caatggtcca
      181 gttttagaag aactggttag aaccccgttt gatggttata actactcaga acagttgtgg
      241 ggcaatactg acaatcttgt caagaatctc caaaagaaat taaaacaagg ttttgttcgt
      301 ggcgagcatc ctagagcgat agccagagat ttagctaagc aatttaatgt tgctaatcac
      361 agggctgaaa cactaatcag aactgatgga actatggtga ttaataatgc taccgctagg
      421 cgctacttgg atgcaggact taagtattat cgtgatttag ttaggcttga tgacaggaca
      481 actgagatat gtcgtaaaat cgctaaagaa aacaaaagaa agctattatc tgagctaaag
      541 cctggaatta atgcagcacc ttatcatttc agctgcagaa caacccttat tcctgatgaa
      601 gatgagctaa gcattgaagt agaaccaatt gatgataaaa gcactaagta ttttaaggat
      661 gtcacctcag attggataga tggaaatggg cataaaccac aactgtcact actaaatgag
      721 tatgtaaaaa atggcactcc ttacaaagta gatggccata atgttgttct tgatcactcg
      781 aattatgaat atagagttgc taattggtta tctaaaaaga caggattgca agttgacatg
      841 gtgccaagag ttaattcccc tgaacatatc aatactcctg attatttagt tgatggagtt
      901 ccttttgatc taaaagaaat cacaggttcg ggtaaaaacg tcattgatgg caatctacga
      961 aaagcaaaaa agcaggcaac taatatcatt tttgatataa caaaaacccc tttatcattt
     1021 gaagagataa tggggcagtt agaacaaatt tatatgatag atcgtagggg tcttgatata
     1081 tcaattatca aaaataaaga tgaggtatta gctgtattag aaaaagaagg atgatgaccc
     1141 accgcctcca cagtaaactg cttcgtgggc gttagaccat catccttctt tatctcaatt
     1201 atacatcacc ctattaaaac tatcaaggag gaaaatatgt ttatttggca aatggtatta
     1261 gtggcactag gtgtattggt gctcatattg attgttggca ttgcagcaat agcggttaag
     1321 tcaattattg cagaattgaa aaaggtagga taaacatgaa taagcgcatt aagaaaaaac
     1381 gtaagttgga aacagcggtt gtgatgcttg ttgcagagaa tgccatgcaa gcagaagcaa
     1441 ttaaaaatca aaacaaagaa atcatggagt tgaaatcaat tgttcagcgg aacgctctgg
     1501 caacaaacga agagtttgcg tctgttaaag ctgctacttt agataatcaa gcagctatta
     1561 caaacattgc aattgatgtt aactacatta agaaaaatta taagcgtaag tggggaaaat
     1621 aaattttaaa cgaattcgac ccctttagaa atcaaagtcg tagcaatacg gcttttattg
     1681 tgtccaaact ttgttgatga cactaaaagc tacactgttt cgtcgcagga cgtaaagcta
     1741 gactatcggt tggtggcgta accactagga gaaagttatg gcagaagaga atgtaacaac
     1801 agaaacaact gagcaagtcg acactcaaaa agaagctgtt gaacatccta agcaggaaca
     1861 tgagcgaact tttactcgcg cagacatctc aaaaatgatg gctgccgaac gcactaaatg
     1921 ggaatctgaa caatcagaag ctattgaaaa agctcgtaca gagggtgaac gtttggccaa
     1981 gttgtcaaaa gatgagcgcg ctaaagagga ggaacaaaaa cgtctagatg ctatcgcaga
     2041 gcgtgaaaaa gcagtagcag agcgcgagat gcgcattgag acgcattccc tgcttgtgga
     2101 gaaaggattg ccattggatt ttattgatat tgttttagcc actactgcag aagaggttaa
     2161 gaccaatatt gataatttac aaactatttt tgataaagct gttgaaaaac gtgttaacga
     2221 tcgtttaacc cagaagccac cacgaactgg aaatggctcg gtcggcatga ccaaggctga
     2281 catcatggca atagaggatg atgacgaacg tatgcgttta attgctgaga atcgtaactt
     2341 attttaagag aggaatatta tggctgaaaa aaatttaaac actatggcgg acttaggaga
     2401 tattaaatca attgattttg ttaacaagtt ttccaaaaat attaatgatt tactaaaatt
     2461 gctaggggtc actcgtcgtg aaacattaac taacgatcta aaaattcaga cctataagtg
     2521 ggaagtgact ttagatcaaa ctgatcctgg agaaggggaa accatccctc tgtctaaggt
     2581 tactcgaact aaagataaag actatacagt gaagtggttc aagaaacgtc gtgcaactac
     2641 agctgaggca attgctcgcc atggcgcagc tcgtgctatt actgaagcag ataagcgcat
     2701 tatgcgtgag cttcagaatg gaattaagga tgcattcttt acattcctca aaacaaaacc
     2761 aacaaaagtt aaaggcgttg gccttcaaaa agcgctgtct gcatcatggg ctaagctagc
     2821 tacttttaat gagtttgagg gttccccgct tgtttctttt gtctctcctt tagacgtagc
     2881 caactatctt ggagatacta aagtaggtgc ggatgcctct aatgtttttg gaatgacatt
     2941 gcttaagaac tttttgggta tgcaaaatgt gattgttatg ccatctgtgc cagagggtaa
     3001 aatctactca acggctgtag agaatctagt ttttgcgtct ttaaatgtta aaggcggaga
     3061 cttgggcggc ttgtttgctg attttactga tgagacaggt ttaattgctg cagctcgtaa
     3121 tcgtcagctt tctaatctta cctatgaatc tgttttcttt ggggcgaatg tgctgtttgc
     3181 tgaaattcct gaaggggttg tagaggcaac aatcgaagct gctgctgtac ccggcattgg
     3241 tggttaaagg ctatttatat gggcgataaa caacttattg acgatatcaa actctttata
     3301 ggtatttcca agggggatgg tgcgcaagat gagctcatca cccttgctat atctgaaagt
     3361 aaagagcgtg tgctagctaa acttaatgaa tactcagaga ctgaaattac caaaattcct
     3421 gatagattga ggtttattgt ccgtgatgtt gccattaaac ggtttaatag gattaattca
     3481 gaaggaaccg ttgaggatag cgaagaagga aagactttta agtgggacag ttaccttaaa
     3541 gagtatgaat caacactcag aagcgctgct attgggaagg tatattcagg caaaggggta
     3601 gcaagattta tttaggagat acacaatgat ctataaagat agagtaatct tagtgtatgt
     3661 cgatgagcag gacgattttc tagataaaag aactgttgaa aaacctagcg ggaaaatccc
     3721 ctgcatggaa aatactttca caaaatctga acagatgggg ctatttggta aatatgattt
     3781 gaatgctttt aagttgcact tgcaaggcca ttacgacggc tttagcaaga ttatctacaa
     3841 gggaaaaccg aggttgataa agggactagc acaccataaa aatagcacgg ttatttatgt
     3901 atgagtctta tttatcggat gagaggctta gataggtttt tacgcagcgt tgagcgcaag
     3961 cagaagtcag tacgaatcgc tgtagataaa gagcttagca aatcagctgc tagaattgag
     4021 agacaggcta aaatactagc cccggttgat actggatggc tgagagctca aatctacaac
     4081 gagcaacaac aactcttaca ctatagagtg gtttctcctg ctttatattc tgtttatatt
     4141 gaattaggta ctcgtaaaat ggaagctcaa ccgtttttag accctgctct gagaaaagaa
     4201 tggcctgtgc taatggctaa tctcaaaaaa atgtttaaga ggtgatgcat ggattactca
     4261 ccagaaacac tatatttaaa aaaggtaaaa aatagattgg gagttttgga cataccaatc
     4321 tattttaaat tgcctaaatc agacgtttta gagcctttta ttgttgtggg tacaaatata
     4381 tcagacttgt caaaaacagc tcaaactgga gcagttattg acgattttag cctgaatatc
     4441 gatgctttct tacctggcga tagtcgtttg gatgcagaag agataaaagc tcgcatgctt
     4501 agactgcttg ggcggaataa ccaaataaag gctcagattt tggtagataa ttcaatagga
     4561 cgagaagtct atagagttgc tatcaacatt acagaaacac tattttaaag gagacctaaa
     4621 tggcaaacac taaagaagga acaactattg aaattacaac aggtaaaccg attgtaggga
     4681 aaaagatttt ttatttcatc caatcagttg acgctaaaaa agggagtaag gctttgctgc
     4741 cagcctatcg taccgatggt actacaacca tgggcggtga atacattgat gagcaaaccc
     4801 aacaaggccg cgttattgag aaggctacgg atgaacactc tattgatttg acaacgtact
     4861 ttgtaccgac agatccatct gttgctgtca tcgaggaagc taagaaaacg ggtaaatcta
     4921 tcaaaatttg ggaagttatt gccgacgaaa gcgtcaaaga acaaatccaa attcctgaat
     4981 cgagtggtcc caagaaagat gtttaccctg ctaagtttgg gtacgccaag attgacgaaa
     5041 tcgaacgtgg tactggtatt tcagacttag tagaaatgtc ctacaccgct aacattgtag
     5101 gggccttaca agatggtaaa ttccctctca cgaaagaaga aattgaaatg ctagaaaatg
     5161 tatacggcta tcaaaatccg ggtgatacta ctggcgacta cgataatatc actaagtagt
     5221 acacaggggc ggcgactgct gccccatttt gatttaaaaa ggagataaaa taatggaatt
     5281 tacagcagcg aaacgaaata tcgatattaa atttgatttt aaaactatgt ttaagatcaa
     5341 taataaacta ggaacaatta acccagaaac aggagagcgc aatgcagatg gtgttggtgc
     5401 tttgtttttc aatatcttag agcgtaatga aagcgccatt gttgaccttg tgcgtttatc
     5461 tgcgggaagc ggaaaaaaag cgctaactga agatgaaatt ctagatgcaa ttgcagaagc
     5521 tgttgatgaa gaaggaacaa cagaagggtt gtttgctgaa atagagaaag aaatggttga
     5581 ttctggtttt ttcagagcga agattttgaa atatatcgaa aacatggaga aatcagctcg
     5641 ctatctcaaa gcgaaggacg atacggacgc aactcaaatc caaattatcg aagacatgat
     5701 tggaagaatg agcaacgcag tatcttagta aattgcgcac ggttagggct cacagacatt
     5761 gatactatct ataaatgtac taagtgggag ctagaggcta ttatggaggg gcttgagtat
     5821 aagcaggttg ctgagcgcga gaacctctct gaattgtctc taaaacttag atatacatta
     5881 aatgctaaaa aggttgatgt aggtaagctc aaatatgata agcataggct aactatcaaa
     5941 agatcgtatc aaaaagctag ccgtagccaa gccgatagtg atagcagtat tgttgagaga
     6001 atacaaatgc ttaataatca ttttcaaaat agatagataa ggaggagtag atgccaggaa
     6061 catttgatgg ttctattttc gctgatgttg gtgccaacac aaaggactat gagcaggcca
     6121 tggctcgtat tgttagtacg actcagaatg ctttcagaaa agcccaagat acagcggtta
     6181 acagtagtaa taaaatggtt caaatcattg gacaaatcat ggcccaatta gcgaacaacg
     6241 gcgaatcgct cggaaagaga cttggttccg cctacgctac tggtttaaaa ctgagcattg
     6301 gtgaaattca acgtatagca gcttccattg gcgaaaaaat tcccgaaccc ataaagaatg
     6361 gtttcaataa agctttttca attatccaaa atagcgtaca gaagttatct agcgccatcc
     6421 ctcaccccat aaaatccgca ttcacaagtg caacaagtgc agtagttagc ttttcgtcta
     6481 agatcacaag tgccgtctca gcagctttca actctgttag ttctaaagcg agtactgttg
     6541 cagataaaat cagtagtagt tttgggggta gaatcacttc agcggttact aatttagcga
     6601 ctaagttaag tacaggtctt agcaatggtt ttagcagaat gtctagttct gcggctactt
     6661 ccttgaatgg aatcagccag aaattcgcca acacctcttc tgctggagag agactcaaaa
     6721 gtacagtgat gagcatcgtg caggccttta gtttaatggc tgttgctcaa aaagctatgc
     6781 acgctcttac tggggcaata ggcggggcgg ttagtcgggt tgataccatg aaccgctttc
     6841 cgaaaacgat ggcactattt gggtattctg ctgaacaatc taaggcatca attgataagt
     6901 tgtcaaaagg aattgaaggt ctgccaactc ccctagatag cgctgtgaaa agtgctcagc
     6961 agctcgccat aaccacagga agtttagata aaggaactag tttagccctc gccttcaata
     7021 atgcaatgat cggttacggt gcaacaactg aaggggctga gcaagcactc aggcagttta
     7081 accagtcgtt ggggtctgga aaaattcaag ctgaagagtt taactctgta tcagaagctg
     7141 cgccgggttt aatgtctaaa atggcggaag ccttcggttt tggtaaaaat ggcgtacaag
     7201 atttaaaatc agccttatct gatggcaaaa tcactgcaca agagttcgca gataaaatga
     7261 ttgagcttaa cgatgcccaa ggcggatttg cagagatggc ccaatcatcg gctggtggaa
     7321 tccgaactgc gtggaagaac gtacataccg ccgttgtaaa aggcgtagca ggtatgattt
     7381 cagcctttga tgaagcggct aaagctaatg gtatgaagac cattgctgaa acacttctta
     7441 gtctgaagcc agcaataacc agtgtttttg atacgattaa ttctcttatt ccaaatgcag
     7501 ttgcagcatt cgctaggcta aaacagtcta tcaatattga ctttagccca ttaggcgcca
     7561 gcgttaaaga ggtgtttgct cttattaata ttgtttttgg agattttgca catactggtg
     7621 aattatcaga gcaggctttt gataatctaa aagcaaaaat cacttcttta gctcctaaag
     7681 tcattgccct ttgggcagtg atgaaccccg ctagcgctat atcaacgata atgcctttgc
     7741 tttctctatt cggaaaagtt ggtctagctt taggaagctt agggacttct gtcggggcgt
     7801 ttggcggcat aatttctagt gggatagcta gtgccagcgg cgttgttggt gcctttgcgg
     7861 caactctaag cggattacct ggcgtttttg ctaccgcagc agggcgtggg ctatctgtgc
     7921 ttggaactat gacaagcgca atgtccagtc ttgtgagttt agcactggcg gccataggac
     7981 cggccgctat tctaggtctt gtggtggcag gacttggttt gattaatagt cagtttggcg
     8041 cacaaatcga gcagctactt aacaccgcag ttacaaaagg tcctggcatt attcaaggcc
     8101 ttgtaaaagg aattacttct aaaataccag ttttgatagc tagtggcact caattgattg
     8161 ctaaatttgc aaatgctatc gcagtgttat taccagttat aattcaagct ggcgttcagc
     8221 taattacgag tctcgtccaa ggtattggac aaaatgcaac gaatttaatt agttcagcaa
     8281 taaaaatcat tggtagtttt gttagttcaa ttgcgagtgc attgccgcag cttatttctg
     8341 ttggaatgga gctattatta aatgttgtca acggcatagt tcaaaatata cctcttatta
     8401 tccagcaagc ccagcaaatt attgatagtt ttgggaatag tttacaggct aaccttccta
     8461 gtattattag caacggtata gctattttgg tgaatcttgt acagggaatt actcaaatgt
     8521 tgccaactgt tctgcagata gctactcaag tcattacgag ttttgtatct ggaattgtac
     8581 agtttttacc gcagttactt caaggtggca ttcaaatcat tattagcctt gtgcagggga
     8641 ttattcaaaa tctaccccag attgcacaat ctgctgtaca gattatacag tctttagctt
     8701 ctggactgac gcaagctcta cctcagatta tcgcagcagg cattcagctt gttgcgcaac
     8761 tagccgtagc cttgataaag gggcttccac agattatttc tgcgggtatt caattaatta
     8821 tggggctcgg taaagccatg ttaggggcta tcccaaacgc tctttcagga gtttgggaag
     8881 gtattaagag cggattcagt tcgatgtggg accaaatcac aggtaagagt tccacaagta
     8941 cagctaaagt ctctgcggac gccacggtca tggccatgaa tgttgggatg caaacgacag
     9001 ctatggctaa tcaagctaat acagatacga catctatgct taatagcatt agtcaaaata
     9061 cagagcttgc taa
//
LOCUS       DARYJX010000061         8116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYJX010000061 DARYJX010000000
VERSION     DARYJX010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(3..2006)
                     /locus_tag="TU257_001868"
     CDS             complement(3..2006)
                     /locus_tag="TU257_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL0834848.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTM
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLETDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQAQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2133..3749)
                     /locus_tag="TU257_001869"
     CDS             complement(2133..3749)
                     /locus_tag="TU257_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0834849.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4165..5709)
                     /locus_tag="TU257_001870"
     CDS             complement(4165..5709)
                     /locus_tag="TU257_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL0834850.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDFEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5878..6573)
                     /locus_tag="TU257_001871"
     CDS             complement(5878..6573)
                     /locus_tag="TU257_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL0834851.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(6657..8042)
                     /locus_tag="TU257_001872"
     CDS             complement(6657..8042)
                     /locus_tag="TU257_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL0834852.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2469 a         1932 c         1519 g         2196 t
ORIGIN      
        1 acctaggcct tttcatcttt tgtacacgct ttgatttcct tgattggaag ctttaagaca
       61 tctgataaga gtaaaggaac aacctcaact gttgcctcag aatattgcag gccaaaccaa
      121 cgcatagggc ttgctgtcac atgcttgata ctagcctttg tctgcatgac aaaacgttcc
      181 agagtactca gctgccttgc atgcgacacg cgctcctcaa tgatcacaaa cctaaagtca
      241 ccaacctctc gacctggtgt aatcgtgtaa tcctgagctt gcttaggcag acgaccactc
      301 tccatcaaat cctgaacaat cgttctaagg taacgtggaa cagtctgtgg cattctaaag
      361 ccaaggtaga gctctacaca aacgatatag tctgtttcta acatatccac cttgtaggtc
      421 gccgtataag gctcatctgt cacacgaaca ttaacaaacc aataaacctg tgcgcgctta
      481 ggacgcttat ctaaaataga atacaggatt gagcgatcaa tcagatcttt tttcatgcga
      541 ttggtcaagt aaacaacatt ggtctgatac aaatcaaagc gaagatcatc tctgaggagc
      601 ttgatttgat gcttgtaatc atttaggctc aaggacttaa catatttagc aacaatcatg
      661 gttccagcat gccaaatcac cataacaaag acaatggcaa gagctaaaac aacaacaaca
      721 tagcccccat gcataaactt aactgcagac gctaaaaaga aaataaactc aataaaggca
      781 aaaaaagcca tgagcagact agccaggagc ggctttaccc cctccttaat aaggtaatag
      841 gctaagagaa tcgttgtcat cagcatggta atcgtgatgg caaggccata ggcagcctcc
      901 atatgcgctg atgttctaaa atacagcacc gtacaagacg ttaccgcaaa caagctccag
      961 ttaatgacag ggatgtatag ttggcctagg ttggcacctg gataggtaat cttaaacaac
     1021 ggaaaaatct tcaagcgcat agcctcagaa accaaggtaa aggaacctga gattaaagcc
     1081 tgcgaagcaa taatggctgc tagagttgct agaataacaa gataaacccg taatccctct
     1141 ggaacactag caaagaaggg attaagcgca atgcctgagt ccttatgcgc taaaatccaa
     1201 gctgcctgac cacaatagga taagatgata caaaccttaa caaagggcca gctagcataa
     1261 atatttcctc gaccgacatg acctaaatca gaataaagag cttcagcacc agttgtcgct
     1321 aaaaaaatag agcctaaaat gaaaataccc cgatgatttt ccggactaac caataagtgc
     1381 agcgcataat agggattgat agcctttagg atttccaaat gctgtaagct attcaagaga
     1441 ccactgatcc ccaaaacgct aaaccaaacc agcatgactg gcccaaataa tttaccaata
     1501 acacccgttc caaagcgctg caggccaaac aagaccatca atatcagcaa ggtcgttagg
     1561 atcacattgg tctgattctg gtaaatactg ctgagctcag gaacagcctt taagccttca
     1621 atggctgatg tgaccgtaac agctggtgtc aaggcaccat ctgataagag cgttgctccc
     1681 ccaagcatag ctggaatgat taaccacctt gacatccttc taactaaggt aaagagtgaa
     1741 aaaatccctc cctcatgatg attatcagcc tttaaagcaa tcaaaacata cttgattgtc
     1801 gttaccaagg ttagagtcca aataatcaag gatactgagc ctaaaataaa agcttcagac
     1861 acctgtgaaa ggccgccttg attgtcaacc aacgactgca tggtatacag tggacttgtg
     1921 ccaatatcac catagacaat tcctagtgca ataataaaac ctgcctttgt tgctttatca
     1981 aaggcatcat gatgggcatt agacatccca atgttcctcc taagacttaa tcatgccaaa
     2041 tggactgaga ccattatagc aaaatctata acaaaatcaa tattttcaga aaattaaaaa
     2101 gagagctgac aatcatcagc tctcttgaaa ctttagttcc ctttatgacg gataataaat
     2161 ccagacgtct tagcttcgac agccttgccc ttcttgtgca ggtccttgtt agagcgtttt
     2221 tgctttcgct taaagtcata gctaccactg ctatcatgac tgtcacgttt atcacgcctt
     2281 ggacggcggt caccatcata aacatttctt ttctcatgac gatagccacc tcgacggtta
     2341 tcacgaccgc tacgactacg attgccacga cctgtcttgc catttttatt gccatgacca
     2401 ccaccaacat acttaaacgg taatggcttt tcacgcgcta tctcaacctc tggtaaggta
     2461 tctggatctt ggacggtcaa gctaaggata tagagcgcta gctcctctgg ggtaaactct
     2521 gctgccaatt tcatcgcatc gcccttaaat ttctcaaagt ttgagcgaat agcatcatct
     2581 gcaaaatcac gctcaatttt tttgagggca acctttttct tagcctgaaa ggcttcctct
     2641 gccgtagctg gcttgagtgg cttcatgcgc ttcttagtca ggtgctcaat catggtcaga
     2701 tagcccatct catttggtga gacaaaggta atggattccc ctgacttacc tgcacgaccg
     2761 gtccggccaa tacggtgcac atagctttct ggatcctgtg taatatcgta attgtacaca
     2821 tgagtaacgc ctgaaatatc aagcccacgc gcagcaacat cggttgccac taaaatatca
     2881 agttgatcat ttttaaagtc gcgtatgaca cgaaggcgct tattttggtc aaggtcacca
     2941 tgtatccctt ctgcgcgaaa accacgcaat tttaagccgc gcgtgatttc atcaacacga
     3001 cgctttgtgc gaccaaatac aattgatagc tctggctgct gaacgtccat cagacgtgtc
     3061 atggtatcaa atttttcttg ctccttaaca cgcacatagt attgatcaac attcacattt
     3121 gttaattcct tgtttttaac ctgaacatgc tcaggatcct tcataaactt gacaccaatt
     3181 tccttgattg gagctggcat tgttgctgaa aataacaggg tttgacgatc gtcagggaca
     3241 cgactaataa tcgcttcaat gtcctctaaa aatcccatat tcaagcattc atcagcttca
     3301 tctaaaatga gtgtctcaac atggtctagc ctcaaggcct tacgcttaat caaatctaac
     3361 agacgtcctg gcgttccaac aacgacatgc gccccagact ttagggcctt aatttgcttc
     3421 tcaatgcttg agccaccata tactgagcga accttgacgc ctttatcacg accaaaacgg
     3481 aacagctctt cctgactttg gacagccagc tcacgcgtcg gagcaatcac caatgcctga
     3541 atggtgttat cggctgtacg aatcttattc agagttggta gaccaaaggc tgctgttttt
     3601 cctgttcctg tctgagcctg tccgataaca tctcgtccct ccaaggctaa cggaatggtc
     3661 agctcctgaa taggagaggc tttttcaaag cctgctgtaa caacagctga ctgaatatct
     3721 tctgataagt taaatgctgt aaatttcaat tgtttctctt ttctaaaaag gcagtgcgaa
     3781 gctgccttat aaacctttta atattgtcgt tcgattaaca acctatttag tgtaacataa
     3841 ttaatattaa aaagatagga aataagccat gaaagtgttt ttatctcaaa atgattaaca
     3901 ctatcaggca gctaaattga taaaagcgtc actccttatt gctgattggc taacagcctc
     3961 aaaaaggcct cgtcggactt gcttacctat gctttttatc tactctgcta aaaagactcg
     4021 gcacagagac gagccttcgc gattccatca ccaatcttca aagacagcaa ttaggattcc
     4081 tgaaagctcc ttatgccaat agcctgcctt ttcttagcag cagaagtgca aaaacggact
     4141 aggttcccct aatccgctta gctgctacat ttttgcttct agcttaacat ctgggtattt
     4201 atctgcaaac caacgaagcg caaagtcatt ttcaaagaga aaaacaggct gatcaaagcg
     4261 atcccttgcc aaaatgtttc ggcttgagga catgcgttgg tccaaatcct cctctgagat
     4321 ccaacgaaca gtctttttgc ccattggtgt catgatgacc tctgcattgt actcaccctc
     4381 catacggtgc ttgaaaacct caaactgcag ctgaccaact gcgcccagca tgtattcacc
     4441 tgtctgataa ttcttataaa gctgaacagc cccctcctgt acaagctgct caataccttt
     4501 gtggaaagat ttttgcttca tgacattctt aggtgcaacc ttcataaaaa tctctggggt
     4561 aaaggtcggc aatggctcaa attcaaacag gtttttacta acgctcaagg tatctccaac
     4621 ctgataagtc cctgtatcgt agaccccaat aatatcaccg gcaactgcat tttggacatt
     4681 ttcacgagac tcagccataa actgagtaac atttgatagc ttaacgcttt tacctgtacg
     4741 agacagcttt acagccattc ccttttgaaa ctctccagag acaatacgca caaaggcaat
     4801 gcggtcacga tgcttagggt ccatgttagc ctgaatctta aagacaaagc ctgaaaaatc
     4861 ctgattgagg ggatcaatca tctggtccgt tgtcgtctta tgcccatgag gctctggtgc
     4921 aaaggctaaa aaggtatcta aaaaggtttg taccccaaaa tttgttaagg cagagccaaa
     4981 gaataccgga gtcagctgac catctaaaat agcctgctct gaaaagtcat tacctgcctc
     5041 ctccaagagc tcaatatctt caagcacctg ctcataaaaa gggttgctgg caaaaatcct
     5101 tgccccctcc tctaaatcag caaacctctg ctccccctta taaagctcca agcgtttgtt
     5161 gtgcaaatca tacagacctt caaaggctcg tcccatacca attggccagt tcatggggta
     5221 agaagcaatc ccaagaacct cttctagctc ctccaacaac tccaaaggct cacgtccatc
     5281 acgatctaat ttattaataa acgtaaaaac aggtatgtta cgatgcttaa caacctcaaa
     5341 gagctttttc gtctgtgctt cgatcccttt agccgaatca acaaccatca cagcagcatc
     5401 aactgccatt aaggtacgat aagtatcctc tgaaaagtcc tcgtgaccag gtgtatctaa
     5461 aatattgata cgcttaccag cataatcaaa ctgcatgact gatgatgtga ctgaaatccc
     5521 acgttgcttt tcaaaatcca tccaatctga cttagcaaat tgaccagatt tttttccttt
     5581 aacggtccca gcctcacgaa tctcaccacc aaaataaagt aactgttctg taatagttgt
     5641 tttaccagca tctgggtgac tgataatcgc aaaggttcga cgctttttaa tttcttctgt
     5701 aattgacatt cttttttcct tatttgttca cattgcagag caagactctg attaatagct
     5761 tcaagtcaca cgtcacagtt atgtctacat gatctcactc ctaaatactg atatgataaa
     5821 aagagctgct agagcagctc ctttattata gctgattcga agcgcttttt caacgcccta
     5881 tctttcttta gagagcttca gctctaactg attggcctca ctaaatctca catagataag
     5941 ttcaatcagc ttaattaaac cagtcaaccc cattgtcaca atgacaaaat tcataagcag
     6001 gtgatgcgta tgaataatcg gaatatccat cacaaagccg taatttccct ttgttgccaa
     6061 attgatcaat actaaaacaa aattaatggt tgccaagtaa cggcaaacaa ggactggctt
     6121 tagctgactt ggattgtaaa accgcagcag gtaaaccaag ccattgacca aaagagcata
     6181 atgccccagg taaaaagaaa tattagccac atgccatagc tgataagggt ataaatcagg
     6241 tgataacagg gccaaaaagg tcccaccaat ccctaaaacc ataaaaagct gctttaagct
     6301 actgcgatcc ggtaagaaaa agatagctag catggccatt cggcaatggt aaagcggcaa
     6361 agcctctgtc aacggaaagc ctcgcaaggc ataccagcta tacaaaccaa ccaattggac
     6421 caactgaagc cctaagaaga tatagcgata cgactttagc tgatagagct gcagggtcat
     6481 aaaaaccaaa aacggcgcta tcatcaccga caatagataa aatagcaagg acacatgcgg
     6541 tagcccaata ggttcaattg caaaaaaatt cataaacatc cctttctaca ttttttcatt
     6601 ataccttaat cttaatgaga ggacaagatg tttcatgtgt tttttctgaa aaagtgttag
     6661 gaggacttcc cagcatgagg agctgtcagg cgatcaacca catttgctag cagcatggag
     6721 tggctgccct ttagcagcat ctggtcatta ggctcaagaa tagtcaacag gtactggcac
     6781 atgtcctcgt attgatcctc tcgattattc tttttaaaga agctaactct gccacttgga
     6841 taatcttgac tagctagctt ggccaaggct tgaatatcat caccgtaaaa gaccaattga
     6901 tcaatacgct tgggatctaa gctggtaatc agctgagaat gcaaagcaac tgagtcagca
     6961 cctaattcct tcatatcagc taaaacagct atttttttgc cattagggtt ggccggaatg
     7021 gcagcaaagg tttccaaaat taaccgcata gcagttggat tggcattgta cacatctgcc
     7081 aaaaggtcgg cgccattagc cgccttgacc cactcggttc ggtggcgtgt cagcttgacg
     7141 gtttctaaag cttctataat atcctcatca ggcacagcca agagtttacc aacataagct
     7201 gctatcatag cattggttgc attgtatttt ccagttaagg gaagagtgac cggtcttggt
     7261 aagacattag tcctaaaggt caaggagtcc ttgcactctt tgatatcctc aaccaccagc
     7321 tcttgatgat cgccaaagcg aatgaccatc tgactatccg gcaaatatgg atcaaggata
     7381 ggatcaccag gagcaattaa aatcccgtta gagtccatcc catcaacgat ttgcattttc
     7441 ccttcggcaa tcttctcgcg agagccaaag taggctaagt gagcctcacc aataagggtt
     7501 agcaatgcaa tatgaggtct ggcaattcta gagagcagct gaatgtctcc catatgatcc
     7561 tgccccatct ctaaaacaat cttctcagta tcctctggca tgtgaagcac cgtataaggc
     7621 aagccaatgt cattattata attgccctgg gttttgtagg tcttataagc ttttgccagg
     7681 accgcttcaa tcatatcctt ggttgatgtt ttaccgtttg agcctgttac agcaatgaca
     7741 tcgacacgta gcttatcaat ataatactgg gctaattttt gaaaggcagc caagcaattc
     7801 tcaactagta tatagggtct gccactgatt gctctttctg aaaaggtagc tacggcccca
     7861 ttttcaaagg ctaagtcaat aaaatcatgg ccatctcgct caccctgtag cggtaaaaaa
     7921 agatcacctt ttgtgatgtt tctactgtca aattcaatct gattcagagg aacgtcgtct
     7981 aaatcagaaa gactattttg agcatcaaca actcttgcca cttcatgtaa tgttaatttc
     8041 atcttatttt tcctcttaaa acactggttt ttaaagcttt gcttatatta tagcataaca
     8101 tattaggaat attctt
//
LOCUS       DARYJX010000062         8113 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYJX010000062 DARYJX010000000
VERSION     DARYJX010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8113
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..4934)
                     /locus_tag="TU257_001873"
     CDS             complement(<1..4934)
                     /locus_tag="TU257_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL0834853.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQMLLNSDFEKETEEYKKQKDEYINFI
                     DELNFKVNRIIFNVIRKCGVFSDESYITLEDIIKKINPIDSLKNLIKSWIYNLCEEGL
                     IKRNDSNNYCISKFMCDDEKYDVIKTKEKDIELNRYLQVLETYLLEMIQGKVNPINFF
                     YTTNPELSPISLSKLLPWHEDVMECIFNYIEIDVDGNDKENIILDYDSKNDFLSQRID
                     EISDRCVHLHFDKTLNVINKVSGDFKNENDFESLENKLDYIVAFNSIHRTVNIKETMK
                     KLRNLLTNNGKLIVVEPKERIRIQDITTSILNNFAGYNDNIFNVDEWNSIFYDANLNC
                     CKQISVGGSIVYILEKRIQFVDIETIKAKMRNMVPIYMVPDDIVLLKNMPQNKNGKVD
                     RKKLEEIYKDKKLQGNIFDMILDDREIETLKDIWKEIFGYDTKYRTSFFSNGGDSLIA
                     TKLSAKIEEKFKISFSIKDVMENITIEAQAQVIKDRIAEQRFADKISVIEETITEEEF
                     DLTDVQHAYYVGRNKDMILGGVSTHCYFEIESSDIDVNKLEKAWNYLIKIHPMLRAII
                     TENGKQKILQEVEYYKIMTSADSELIIRDIMSQQVLNLDKWPIFDIRISKREDKADII
                     HISFDNIILDGWSMFFILEQWSNIYKYGKYEEAI"
     gene            complement(4949..6532)
                     /locus_tag="TU257_001874"
     CDS             complement(4949..6532)
                     /locus_tag="TU257_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0834854.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            complement(6541..7224)
                     /locus_tag="TU257_001875"
     CDS             complement(6541..7224)
                     /locus_tag="TU257_001875"
                     /inference="COORDINATES: protein motif:HMM:NF013786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HEL0834855.1"
                     /translation="MKIYRIEISDKKELRSLIDISRLLIFFDMVLVTSNTSEFMIKDL
                     KNFLKEEEIEKLDAYKSEVAKINFAVSRSLLNKVFEMILGVPIENIVSFRDKHNKPYI
                     ENKSGVKFNISHTDGFVVIGFSKKELGIDIEKVNDGFAFEDILENCFTSREIKNIGSN
                     IPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDNQRIKIEDKVKRSNKDLIAFSIS
                     SKYFGAICI"
     gene            complement(7211..7960)
                     /locus_tag="TU257_001876"
     CDS             complement(7211..7960)
                     /locus_tag="TU257_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL0834856.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFVYSNENI"
BASE COUNT         2506 a         1655 c          845 g         3107 t
ORIGIN      
        1 ttaatagctt cttcatattt cccatatttg tatatattag accattgttc cagaatgaaa
       61 aacatactcc atccatccaa tattatatta tcaaaactaa tatgaattat atccgcttta
      121 tcctcacgct tgctaattct tatgtcaaat ataggccatt tatccagatt aagcacctgt
      181 tgtgacataa tgtcacggat aatgagttct gaatctgcac tagtcattat tttataatat
      241 tctacctctt gcagtatctt ctgcttacca ttttcagtta taattgctcg taacatcgga
      301 tgaattttta ttaaataatt ccacgctttc tccaacttat ttacatctat atcacttgat
      361 tctatttcaa aataacaatg agtagaaact cctcctaaaa tcatatcctt gtttcttcca
      421 acataataag catgttgaac atccgtcaaa tcaaactctt cctctgtaat agtttcctct
      481 atcacgctaa ttttatccgc aaaacgctgc tcagcaattc tatctttaat cacttgggct
      541 tgtgcttcaa tagtaatatt ttccattaca tcttttatac taaaacttat tttgaatttt
      601 tcctctattt tagctgatag ttttgttgca attagagaat ctccaccatt tgaaaaaaag
      661 ctagttctat actttgtatc atatccaaat atttctttcc atatatcctt taaagtttct
      721 atttctctat catctaaaat catatcgaaa atattacctt gcaatttttt gtccttatat
      781 atttcctcta gttttttcct atcaactttc ccatttttat tttgtggcat atttttgagt
      841 aatactatat catccggcac catatatatc ggaaccatat ttctcatctt cgccttaata
      901 gtctcaatat caacaaactg tattcttttt tctaatatat atacaatact tcctccaact
      961 gatatttgct tacaacaatt aagatttgca tcgtaaaaaa tactattcca ttcatcaaca
     1021 ttaaaaatat tatcattata tccggcaaaa ttattaagaa tacttgtagt tatatcttga
     1081 atgcgtattc gttctttagg ctctacaact atgagtttgc cattattagt caacaagttt
     1141 ctcaactttt tcattgtttc cttaatatta actgtcctat gaattgaatt aaatgccact
     1201 atataatcca acttattttc tagagattca aaatcatttt catttttaaa atcacctgat
     1261 actttattta tgacattaag tgttttatca aaatgtaaat gaacacatct atcagaaatt
     1321 tcatctattc tttgactcaa aaaatcattc tttgaatcat aatctaaaat tatattttct
     1381 ttatcattac catcaacatc aatttctatg tagttgaata tacattccat tacatcttca
     1441 tgccaaggta ataatttact taagctaatc ggtgatagtt ccggattagt agtatagaag
     1501 aaatttattg gatttacttt cccttgtatc atttccaaca gataagtctc taatacttgt
     1561 aaatatctat ttaattctat atccttttct tttgttttta tcacatcata tttttcatca
     1621 tcacacataa atttgcttat gcaataatta ttgctatcgt tcctttttat tagaccttct
     1681 tcacacaaat tatatatcca agattttatt agatttttca gtgaatctat cggattgatt
     1741 ttcttgataa tatcttctaa ggttatataa ctctcatcag aaaatacacc acatttacga
     1801 ataacattaa aaattattct gtttacctta aagttcaatt catctatgaa attaatatat
     1861 tcatccttct gttttttata ttcttcagtc tccttttcaa aatctgaatt caataacatt
     1921 tgattacttt ctttgcaatc aaatatttcc gcaaatccta caagtttatt aacatttcca
     1981 tctttaacaa ttaaagcgat cgcttttttt atattttcaa atacaattaa agcattctct
     2041 atttctccaa gttctattct atgtccttta acttttacct gagtatcttt tcttccaaga
     2101 aactcaataa tcccatcatt ccatgttcta ccattatctc cagttctata ccacctcatc
     2161 ccatcttgtt cgaagtactt tttattcgtt aattcttcgt caccatgata acatttagca
     2221 acaccaactc caccgataag aagttcacct ttaacataat tagggcagat cctaccaaat
     2281 tcatccacaa ctctatacac ttgatttttc aaaggtctac catatggaat ggaaatccaa
     2341 tctttcggta tttttcttgg tacattcaaa tggtttgacc aaatagatgc ttctgtggct
     2401 ccacccatag cgacaacaat agaatttata ttttcactaa tattatagaa tctttctggt
     2461 aaatttatag caatccaatc ccctgaaagc atcacaattc taaaaggtaa gtttctattt
     2521 ttaccttcag ccatagtaac aatcatatca aacaaaatcg gcacagaatc ccatattgta
     2581 accttatatt catcgactaa atttaaccat tcatcaggat ttctataatt atcttcactt
     2641 gttgtaataa ccgttcctcc agcatgaagt attccaaaaa tatcataaac cgacaaatca
     2701 aagtctattg ccgacaccat cagtattgta tcttcagcat ttacattgta tttttcattt
     2761 aaatcaatgc aagtattaac ggcacttgta tgcataatct caacaccctt aggaacacct
     2821 gttgttccag acgtcataat aatatacgca ctatcataag ggctaatttc aacaggttgc
     2881 tttaatttag ccacatttgc catagctaca tccaaatcaa taattttaac ttcattttta
     2941 tttaatttac aatctatcac tgtcttttca tcacttataa tgcactttat tccgatttga
     3001 tcataaattt tagttcttct atcatttggc tgagcaatac caattgatac atatgctgca
     3061 ccggtaaata aaatcccaaa aatagcataa agttgtctgc tacctcttgg aagtgttatt
     3121 cctacataat ctcccttttt aacaccattt ttacctaaac aatccgcaac ttttaaagag
     3181 atttcataaa gtttatgata tgttatctct tccttcgttt cagaatctat aatcgcaact
     3241 ctatctggat tgagttttac atttctgaga aatccgtcat ataacgtttc gctaggatat
     3301 tgaagtggta aaattccctc aacatcctgc attctaatag acttttgctt ttcaggtaaa
     3361 acatctactt tcttttccca ttcttccttc tgtgttaaag atatgatcaa ttcatataaa
     3421 gaatccatca tgtcttctaa cattcctgtt ggaaaaagtt catccacgct atcccagcaa
     3481 agaattaaat ctccatctac aatatatgtt tgaaaatcaa gccaaactcc tggtgtttga
     3541 gaaatcatat aagatacttt ccctaaattt tttcttgaaa attcagtttc caatggataa
     3601 tctatattac acgcaaaaac cacaggtgct atatacacac ttgtaccttg tttttttgat
     3661 atatctcttt gaacctgcac tccgttatac tcactgtgag atacattttc caagaatgtc
     3721 ttatttattc tctttaaatt atctaaaaaa tttgaatcat ctacagcctc atgctctacc
     3781 aataaaatat ttgtaaaatc agcaaccatt tcttttagat tttcattttc taaatctcta
     3841 ttaaatagcg gtatattgat aaaaaattta tcctgattac accatctttc aagaacaaga
     3901 gcataggcag ttagaagaac catagatggt gtacttcgat acgatgctgc tatatctttt
     3961 atggtttccc attcactttt tttaataatt ctctttcttc ttgtaaactt cgtttcttta
     4021 atttgttccg gctgtttcct taatggtaag ttcggtcttt ctatttcaaa ggaatttatt
     4081 ttttgttccc aaaactcctt atctgcatca ttgattgatt cgccaattcc gttttgcata
     4141 taatccttaa acgtatactc attcaaatta tcaagttcta ctcctgaata aagttcagct
     4201 aattctttaa tcataatact catgctcatt acatcggata caagcaaatc tacgtcaaaa
     4261 aatatccttg acttctcatc tgaaaatttt gctagtgcta ctcctgcaac ctgaccttga
     4321 tttacattta atttcctatg agatttttgt tctctaattt ctactaattt tagatgcagc
     4381 gtttcttcat caagatcaga taaatcaaaa acttctattt cttcactgta cggtttgtat
     4441 aatatttcct gcttcccgtc tttcgtaaat tttgttctaa gcatgggatg tctgtattga
     4501 agcttattcc aagcctcttt taacttatcc tcatcaatat tttctccatc tatttcaaga
     4561 tatgcatggc aacccacgcc acctaaaatc tgatcatctt ctcttccgat taaataggag
     4621 tactggacat ctgttaaatc aaacttactt tcatcacttt ggataattga tgactctata
     4681 ttcttatcac ttttcactct ggatttatca ataagttcat accacttgga caaattcggt
     4741 tcttccataa gttttgcaaa cgaaattttt atccccgttt tctttaattt tccagacagt
     4801 tgcatgactt gaatggaact taaacctttt tcaattaaat tttcattttc tgaaactact
     4861 ttctctacaa atatactttt caaccaatcc tttactaatt ctttagctct ttcttttata
     4921 ttgttaagtt ccattccaaa atcctccttt aaaaagtttc ttttaattta tttctatcta
     4981 ttttccctaa agctgttaat ggccacgcat caatatattt aacagtatcc ggcaatttaa
     5041 aatccgccac attattagaa atcaagaatt ttctaacttc ttccagtgta agctccttat
     5101 ctccatttaa aataaataca gcaatggatt ctccttgcag acgatctggc agccctacaa
     5161 cttgtaccga gttgatattt tcatgagtaa gcaaaatttc ttctaattca agtggtgtta
     5221 tcttttcacc tgctctattg atgatttctt tgatccttcc gacaatttga taattaccat
     5281 cttttagttt tcgtgcttta tcaccagtct taaaataaca atcttgtgtt atacatgttt
     5341 catttacttc aggaagatta taataaccat aaatggtata aggacctcta acgataagtt
     5401 ctccatattc ttcaatccct acaatttttc cttgttcatc cacaatcagt atttcatcat
     5461 gttcactgat tggtttgcct tgtgtttgcc atcttatttt atcgttatct tcttcatttg
     5521 ttgtcaagat caatccttca gcgattccga aaatctgttg tagtttaaca tcaaaaactt
     5581 tttcaatttt ttctgccaac caaggttcca aaactgaacc tccgacttgt ataacctcca
     5641 aagaggaaag atcatactct tcatactcta aataatccat acaaatattg gcaattgcag
     5701 gaacaaatcc tgttatcgta accttttctt cctcaattaa aggtaaaatt tcatcagggc
     5761 ttgtcacatt gcacaaaacc acctttccgc cttttgcaaa agtacccatt atccctggac
     5821 accccaaagg aaaattatga gctattggca aagaagcaag atatacactt tcctgattta
     5881 cgttacaccg gtccgtcgtt ttctttgcaa catagatata atcgcaatgt cttcttggaa
     5941 tcagtttcgg tattcctgtt gtaccgccag ataataacaa taatcctatg ctcctgtaat
     6001 cgacatccgg atatttatag aaacaatcat tctcaataag tgacgaaaaa tttttatatt
     6061 cttcactttc tccaagaata taaatctcca agttcgtatt taattcagat ttcatatccc
     6121 gaaccatatc cacatatgaa aaacctaaat atttatcctt tgaaatatat gctaccgcct
     6181 cagacttttc tataataccc tttaattcat tctttcgatg tgcaggcaaa ctcataatcg
     6241 gaataattcc tgttttaaac attgcaaaag atatcactat aaattcataa caatttggaa
     6301 gctgtaatac aatcttatct ccttttttaa aacctgcttt aagtagtcca ttagcatact
     6361 tattcgaaag tttatcaagc tcatcataag ataagtttaa ttctccatct acaatcgctg
     6421 ttttatcttt atacgtttcc gcacagttcg caacaaactc tcccaaggtc acatgttccc
     6481 aaacattgtc atcataattt ttttctaaat tttctttcaa ttctatattc atacttcctc
     6541 ctatatgcaa attgctccaa aatatttcga tgaaatgctg aatgctatca aatctttatt
     6601 actccttttt accttatctt caatttttat tctctgattg tcgatataaa taacttctat
     6661 ttctttcgga tttcttataa gaccatatcc ttcatatttt aggtaggctt cttttgctgt
     6721 ccaatatcta taaaacattg gtatattact gcctatattc ttaatctctc tggatgtaaa
     6781 gcaattttca agtatatctt caaacgcaaa gccatcattc actttttcaa tgtctattcc
     6841 aagctctttc tttgaaaaac caattactac aaatccatcc gtatgtgaaa tattaaattt
     6901 cactccactt ttattttcaa tatatggttt attatgctta tctctaaaag aaactatatt
     6961 ttcaattgga acacctaata tcatttcaaa gactttgttt aaaagacttc ttgaaactgc
     7021 aaaatttatt ttcgcaactt ccgacttata tgcatcaagt ttttcaattt cttcttcttt
     7081 caaaaaattt ttcaaatctt ttatcataaa ttcacttgtg ttagatgtaa ctaacaccat
     7141 atcaaaaaaa attagtaacc tacttatatc aattaaactt cgtagttctt ttttatctga
     7201 aatttctatt ctatatattt tcattggaat aaacaaattc ttcaattgct tttatcacac
     7261 tttcaggaga tgtatttaca aacatatgct tgccattaat atatctgtaa gagaattctt
     7321 tcgtcgtata atcttgccat tttaaaagtt cttcaagttc catttcttca tcaatatcac
     7381 ccatcagacc taaaatcttg ctattcaatt tttccccttt tgtatcctgg tagtcctcat
     7441 cgataataaa atcggctctt agtgttggta aaaaaatccc aatcaaatct ttattgtcta
     7501 atatctcatt tggagtacca tcatatcttc ttaacccttc aataaatcct tcatcatcta
     7561 aatgataaat cggattcggt tccttatagc aaggggctcg cccagctgat atgataattc
     7621 cattcggatt tggtaaccca ttttctttaa ttttcagagc caattcataa gcaatcttag
     7681 ttcccatact atgcccgaaa aaataataag gtgagttaaa atcaaaagtc atttttaagt
     7741 cttcaaacaa tccttttaca agttcttcta tgttgctaat tgctttttca gaaaacctgt
     7801 tttctctccc tggatactgt gcaacgaaga gatttatatc tttaaattga ttaccccatc
     7861 ttctgaatga tgatactcca ccacctgcaa atggaaacac aaataaacta gctttcgtgt
     7921 tttccatttc tttattaacg tattcgaacc acattcccat caaaacacct tccatctgat
     7981 tattaatata ctactagaac tattattgtt agatacatct aacaataata gtttaatcct
     8041 tctaacataa aaagtcaata catttacact gttttatagt tatattttct atatctaaaa
     8101 ggcttgaaga aac
//
LOCUS       DARYJX010000063         8014 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYJX010000063 DARYJX010000000
VERSION     DARYJX010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8014
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            366..1076
                     /locus_tag="TU257_001877"
     CDS             366..1076
                     /locus_tag="TU257_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834857.1"
                     /translation="MEKAKKAQEEINQRTDKELEEFRAALKNLALPEEAIKKITEAIK
                     VDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRYNKNLLVGEPNRVKKIDED
                     FIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANNKGVKLVLTPTKAKMEPET
                     FTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRNMALGMSYRDVVDGNNADL
                     ILDWAENPDIIFDGNGGI"
     gene            1076..2194
                     /locus_tag="TU257_001878"
     CDS             1076..2194
                     /locus_tag="TU257_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL0834858.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            2209..4095
                     /locus_tag="TU257_001879"
     CDS             2209..4095
                     /locus_tag="TU257_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL0834859.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            4107..4544
                     /locus_tag="TU257_001880"
     CDS             4107..4544
                     /locus_tag="TU257_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0834860.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            4541..5152
                     /locus_tag="TU257_001881"
     CDS             4541..5152
                     /locus_tag="TU257_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0834861.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            5164..5436
                     /locus_tag="TU257_001882"
     CDS             5164..5436
                     /locus_tag="TU257_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834862.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            5433..5660
                     /locus_tag="TU257_001883"
     CDS             5433..5660
                     /locus_tag="TU257_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL0834863.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            5777..7111
                     /locus_tag="TU257_001884"
     CDS             5777..7111
                     /locus_tag="TU257_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL0834864.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            7385..>8014
                     /gene="spei"
                     /locus_tag="TU257_001885"
     CDS             7385..>8014
                     /gene="spei"
                     /locus_tag="TU257_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL0834865.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNSYGGITLSDGNRIDKKN
                     IPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGYGDVKDFG
                     RSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNKTAY"
BASE COUNT         2741 a         1436 c         1773 g         2064 t
ORIGIN      
        1 acgcaactgg agctttagta aaacatgaag tcacttgtaa tgatatcgga tctgtgaaaa
       61 aacaaagcgt aggaagtctg tctataaaca gtagaatcaa tcagatagat gcagatattg
      121 cttctgcaat tgaagtagca acacaagcac tagtatctgc tgacgggaaa aatactgttt
      181 acggtggcac agaaatgccc aaagatgaac caaaaggaac cttaaaaaaa ggagacatat
      241 tattcctaaa agttggcgat actactagaa tgtatttctg gaatggtgct gagtgggaag
      301 aacctgaggt tgtgaacgac ccagaacgat ggcgtgaaga cctcgaaaaa caaatctctg
      361 aggcgatcga aaaagccaaa aaagcacagg aagaaatcaa ccaacgcacc gataaagagc
      421 ttgaagaatt tagagccgcc ctcaaaaacc tagcgttacc agaggaagcg attaaaaaaa
      481 tcacagaggc tataaaagtt gatgacatcc cgtctattaa acaaagcttt gatgacctca
      541 aaaatagagt gagtgagaca agcgaagaat ctcgtttaac tgccgaaatt ttagggaaca
      601 acggtaagac acgctacaac aaaaatttgc tggtcggtga gcctaatcgt gttaaaaaaa
      661 ttgatgagga ttttatcgag gtagaagcta atgatggtgg tttcaagcgt ggcgagactt
      721 acacaatcag ctttagtcag acatgtgagc cgctcaaaaa agtggctatc acgctgatcc
      781 aagctaataa taagggagtt aaactggtac tgacacctac taaggcaaaa atggagcctg
      841 agacttttac tctaattaag gacacagagg tcatcaacgt ctatcctttg agctactcag
      901 tcactttaag tggtgactgg tacaaatcta agcaagtaga tttaaatgcg tcggaggtgc
      961 gaaatatggc tctggggatg agttatagag atgtggttga tggtaataat gctgatttaa
     1021 ttttggactg ggcggaaaac ccagatatta tttttgacgg aaacggaggt atttaatgtc
     1081 aaaagaagtt gcatcagcaa ggatacagca tagaggcatg accaaacaag agtgggaatc
     1141 aagctccgat atcttaatgg agcgagaaat tggaattgat atgactacgg gttacccaaa
     1201 agttggtgat ggcaaaaata agttcaagga cttaaaagac ttgcgcggcc ctatgggacc
     1261 tcaaggtcct tcaggagaaa gaggcctaac tggcccaatt ggtcctcggg gccctgctgg
     1321 caagcctgga acgacagatt ataatcaact ccaaaataaa ccaaatctag atgcgtttgc
     1381 acaaaaaaaa gaaactaata gtaaaatcac caaattagaa tcaagcaaag cagataaaag
     1441 cgctgtttac tcaaaagcag agtcaaaaat agagctagac aaaaaattga gtttgacagg
     1501 cggcatagtg acaggacaac tacagtttaa acctaataaa agtggtatta aaccctcatc
     1561 ttccgtagga ggagcgatta acattgatat gtctaaatcg gaaggtgctg gtgttgttgt
     1621 ctattctaac aatgatacca gtgatgggcc gttaatgagc ttgcggacgg gtaaagagac
     1681 cttcaataaa tcagcgcttt ttgtcgatta taagggaaca acaaatgccg ttaatattgt
     1741 gatgcgtcag ccaaccaccc ccaatttttc atcggcgctt aatattacta gcgacaatga
     1801 aaatggtagt gcaatgcagc tacgagggtc agaaaaagcg ctaggaacgc tcaaaatcac
     1861 acacgaaaac ccaaacgttg aggcaaaata cgatgaaaac gctacagcgt tatctattga
     1921 tatcgttaaa aaacagaaag gcggaaaagg tactgctgct caaggaatct acattaactc
     1981 aacatcaggc acgacaggga agttgcttag gattagaaac cttagtgatg ataagttcta
     2041 cgtcaagtct gacggtggtt tttatgccaa ggaaacttcg cagattgatg gcaacctgaa
     2101 actcaaggac cccacagcga atgatcatgc ggcaaccaaa gcttatgtag ataaagcaat
     2161 ttctgagtta aaaaaactca tactaaaaaa atagattaag gaggataaat gagcagagac
     2221 ccaacactta ttttagacga gtcaaacctc gttattggta aggatggacg tgtgcattac
     2281 acatttaccg cagaggacga caacccaaaa gtcagactag ctagcaagtg tctaggcaca
     2341 gcgcatttta atcagctcat gattgagcga ggagaccaag ctactagcta tgttgcgcca
     2401 gtagtagttg agggtacagg taatccgact ggactattta aagacctcaa agagattagc
     2461 ctagagctga cagatactgc taattcccag ctttggtcaa aaatcaagct gactaaccgt
     2521 ggtatgttgc aggaatacta cgacggtaag atcaagaccg agatagtcaa ctccgccaga
     2581 ggtgtcgcta cacgtatcag cgaggatact gataaaaagc tagcgctcat caatgacacc
     2641 attgatggta tcaggcgtga gtatcgagat gctgatagga agctatccgc aagctatcag
     2701 gcaggcatcg aggggctaaa agccacaatg gccaatgata aaatcggttt acaagctgag
     2761 attaaagcct cagcacaagg gctatcgcaa aagtatgatg atgagttgcg caagctatcg
     2821 gctaagatca caacaacctc aagcggcact acagaggcct acgagagtaa gcttgcgggc
     2881 ttacgtgctg agtttactcg ctcaaatcaa ggcacgagga cagagctcga gtcacaaatt
     2941 agcgggctaa gagcggtaca gcagtcaaca gctagccaaa tctctcaaga gattagagac
     3001 cgtgaaggtg ctgtcagtcg tgtgcagcag agtttggaga gttaccaaag gcggatgcag
     3061 gacgcagaag aaaactatag tagcttgacc catacggtta gagggctaca gagcgacgtt
     3121 ggatctccga ctggtaaaat ccaatcgcgc cttactcaac tagcaggaca aattgagcag
     3181 cgggttacta gagatggtgt catgagtatt attagtggcg ctggagacag cattaaatta
     3241 gctatccaaa aggctggcgg cattaatgcc aaaatgtctg gtaatgagat tatctcagca
     3301 attaacctca actcctacgg agtaacaatc gcaggtaaac acatcgctct cgatggcaat
     3361 acgactgtca acggcacctt taccacaaag atagcagagg ctatcaagat tagggctgat
     3421 cagattattg caggcacgat tgacgctgct aggattagag tgattaacct taacgcaagt
     3481 agtatcgttg gtttagacgc taactttatc aaagctaaaa ttggctatgc tatcactgat
     3541 ttgctcgagg gtaaggtcat taaggctcgt aatggagcga tgcttatcga cttaaataca
     3601 gctaagatgg actttaatag cgatgccaca attaatttta atagcaaaaa caatgcctta
     3661 gtacgtaaag atggcacaca tactgccttt gtacatttta gtaatgcgac gcccaaaggt
     3721 tatacagggt cagcgttgta tgcatcgatc gggataacct catctggtga cggtgttaac
     3781 tcggcttctt ccggtcgttt tgcagggcta aggtcattta ggtacgctac gggatataat
     3841 catactgctg cagtcgacca aaccgagcta tacggtgata atgtcttgat tgcagatgac
     3901 tttagcatca atcgaggatt taaatttaga ccagacaaga tgcaaaaaat gcttgacatg
     3961 aacgacttgt atgcggctgt agtagcctta ggccgctgtt gggggcactt ggctaacgtc
     4021 ggctggaata ctgctcatag caattttaca agtgcggtca ctaacgagtt aaataatcat
     4081 atcaacaaaa tttaatagga gaaacaatgg atttaacgct taaaaacaaa gatttaaaca
     4141 cactatatag tgtactagac aaaatcaaag tcacgaacat gcgagcaaac cgcggacgtg
     4201 ctaagctact cgcaaaagta gtcgataaat tcaaagagta cgccaaggat gagggtgacc
     4261 ttattgatct gtatgctcaa aaagacaaag atggcaagtt tgtcattgat gagcacaaaa
     4321 acatcaagct agcagacccc gctaaactcg acgagttcaa cggcctactc aacgagctag
     4381 ctgatgaaga aattgtgatt aaagggggtg agtactccaa gcgatttatt gactttttaa
     4441 actttttaga agagtgtgaa gatgaattta catcatctga aatcattctt atcgacaaca
     4501 ttttggaaca atttgaagaa agtaaaaaag gagaaaaacc atgagaaatt ggaaagtgac
     4561 aggaaaatac ccacaatttg acagcacagg agcagtcgca agcacacata ttattatcac
     4621 tgctgaggat ggctcagtca tctctcaacc aatcaagcag ggcttaactt caactaatga
     4681 cacagagatt atcaaagcta ctttggaaga atttaaaaaa tctgaatacg tcgaaatcgc
     4741 tatgggcgaa gccgtgcaaa aagtagacga ccttgaaaaa atctcacagg aaaccgctaa
     4801 gaccgctaaa acagcccaaa cagccgcagg attagctaag gtgtccgcag agcgtacaca
     4861 gcggatgatt aacttgcaaa ccatccacgt attgacaagt ggtgggaaag ttgaacccga
     4921 tatctacaaa ggtatgttag agcttattga acctgctaaa caaggcgagt atcaggctta
     4981 tgacgtgttt actgttgtag atgagtcgca cgaagatcaa gcgggagaag gtaatcttgt
     5041 ctttgtacac gttaacgagc cgtttactta tgacaaacag acgcttaaag agctagagga
     5101 agaggataaa gtcacagtca ttaagtatgc ggacttagtt aagcaggatt agcgaggtaa
     5161 gctatggcaa cagagttgat atttggtctt ggtggcttta ttttagctat cgtcacgact
     5221 tacaatattt ttaatgcaaa atccatcaag catgcgacag atattacttt gttgcagtct
     5281 gaagtagagc atttaaaaat tgttacacgc caaaatgctc ggcgtcttga ggagcatgat
     5341 gagcaaaaca aaacgctcat cacaatgaca gagcaaatta aaaacctcaa tcgtgaggta
     5401 agagaactta aagatattat gagaggtgaa gcatgatcaa tttaaaatta cgactacaaa
     5461 acaaagtaac cttgatggct attttaggag ctatcttttt actggcacag caattaggta
     5521 ttaaactacc atcaaacatc gcggatattg caaacacagc tgtaacgctt ttggtattgc
     5581 tcggtgttgt cacagatcca accacgaaag gcctgtcaga cagtgagcaa gctttgactt
     5641 accacgaacc aaaacaatag gaggggacat gcgggcaatc acacgattag cattagttat
     5701 agcaatagca atactgtatg tgccattatc tgttgttgct ttgattttaa gcccattttt
     5761 agataaggag ggataaatgg ctacatatca ggaatataaa agtcgttcaa atggcaatgc
     5821 ttacgatatt gatggatcgc ttggtgcgca atgttgggat ggctacgcag actactgtaa
     5881 gtatctagga ctgccatacg caaactgtac aaatacagga tatgcaaggg atatatggga
     5941 acaacgtcac aaaaatggta ttttaaacta ctttgacgaa gtagagacta tgcaagctgg
     6001 agatgtcgca atttttatgg tagttgcagg tgttacaccg tatagccatg tggctatttt
     6061 tgatagtgat gcaggtagtg gatacggatg gtttttaggt caaaaccagg gtggagcaaa
     6121 cggagcatat aatttagtaa aaataccata ttcaacgact tatcctactg catttagacc
     6181 aaaagttttt aaaaatgcag ttactgttat aggtaatata ggactaaata aaggcgatta
     6241 ttttattgat gtatcagctt atcaacaagc agacttaacc gctacttgtc agcaagctgg
     6301 cactactaaa acgattatca aagtatccga gtcactcgct tggctgtctg ataggcatca
     6361 gcaacaagct aatactagtg accctattgg ttattatcac tttggacgat ttggaggaga
     6421 tagcaactta gcgcaacgag aagcagattt atttctgtcc aatttaccaa ccaaaaaagt
     6481 ctcttactta gtcattgatt atgaagactc tgcaagtgcc gacaaagaag ctaacactaa
     6541 tgcagttatt gcgtttatgg ataaaattgc aaacgctgga tataagcctg tttattacag
     6601 ctataaacca tttacgctta ataatattga ttatcagcaa attatcgcta agtacccaaa
     6661 cagcatttgg atagctggtt atccagacta cgaagtacga acagagccac tttgggagtt
     6721 cttcccttca atggatggtg tgcgctggtg gcagttcaca agtgtaggag tagcaggtgg
     6781 tttagataaa aatattgtat tattagcaga tgatagtagc aaagtggata tacctaagat
     6841 tgacaaacca caaagccagc ttacttttaa tcaaaagcta gatactaaca ctaaattaga
     6901 caactcgaat gtaccttact acgaagcaac ccttagcaca gactattatg tagagtctaa
     6961 gccaaacgca agtagcgctg ataaagaatt tatcaaggca ggaactcgtg taagagtcta
     7021 tgaaaaagtg aatggatggt cacgtattaa cgcttctcag tctgaccagt gggtcgaaga
     7081 taagtattta tctaatgcaa cacaagtata aaataggagg taaagctcct ttagataaga
     7141 caaatgccct cgcttttgcg ggggctgttt ttgttataaa gattttaatt gttatttaag
     7201 cattttcgtt gatttttttc ttttttgtgc taaaatattt tgtgatttct tattattaaa
     7261 gaagaatagg gtacacttat aagtgagaaa aattgtaaat gttaatttta aaaagttttt
     7321 aacttcatct tttctattgt gggtatttat atcagctata attccaacgt gttacgcgta
     7381 tgagatgagt agtgtgggag ttattaattt aaggaattta tactctacat atgatccaac
     7441 agaagtaaaa ggaaaaataa atgaaggtcc gccattttca ggtagtttgt tctacaaaaa
     7501 tattccttat ggcaatagtt cgattgaatt aaaagtagaa cttaatagcg tagaaaaagc
     7561 taaatttttt tctggtaaaa gggtggatat atttactttg gagtattctc ctccctgtaa
     7621 ctctaatata aaaaagaatt catatggagg tattacttta agcgacggta atagaattga
     7681 taaaaaaaat atacctgtta atattttcat agacggcgtt caacaaaaat atagctatac
     7741 agatataagt acagtgagta ctgataagaa agaggttact attcaggaac ttgatgtgaa
     7801 atcaagatat tatcttcaaa aacattttaa tatatacgga tacggtgatg ttaaagattt
     7861 tggccgctcc tctagatttc aatctggctt tgaggaagga aatattattt ttcatttgaa
     7921 tagtggagag agaatttctt ataatctttt tgatacagga catggtgaca gagagagtat
     7981 gctaaaaaaa tacagtgata ataagaccgc ttat
//
LOCUS       DARYJX010000064         7911 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYJX010000064 DARYJX010000000
VERSION     DARYJX010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7911
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..225
                     /locus_tag="TU257_001886"
     CDS             <1..225
                     /locus_tag="TU257_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0834866.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
     gene            694..1296
                     /locus_tag="TU257_001887"
     CDS             694..1296
                     /locus_tag="TU257_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834867.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            complement(1712..2092)
                     /locus_tag="TU257_001888"
     CDS             complement(1712..2092)
                     /locus_tag="TU257_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL0834868.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(2126..3118)
                     /locus_tag="TU257_001889"
     CDS             complement(2126..3118)
                     /locus_tag="TU257_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL0834869.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(3134..3679)
                     /gene="srlA"
                     /locus_tag="TU257_001890"
     CDS             complement(3134..3679)
                     /gene="srlA"
                     /locus_tag="TU257_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL0834870.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(3815..4276)
                     /locus_tag="TU257_001891"
     CDS             complement(3815..4276)
                     /locus_tag="TU257_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL0834871.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(4276..6048)
                     /locus_tag="TU257_001892"
     CDS             complement(4276..6048)
                     /locus_tag="TU257_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0834872.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(6342..7691)
                     /locus_tag="TU257_001893"
     CDS             complement(6342..7691)
                     /locus_tag="TU257_001893"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL0834873.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         2374 a         1783 c         1553 g         2201 t
ORIGIN      
        1 atccaaggcc aaggcgagca tggacataag ggtcaccatg gaaaagatgc taagccatca
       61 gcacctaaag cagattctaa atcaacagca aaagctatgg cgccagcagc tcaaaagggc
      121 acactaccag ctacagggga gacaaatcac ccattcttca cccttgcagc ccttggtgtt
      181 atcgctagcg ccggcatgct aacattaaaa ggcaagaaaa actaaaccag ccattgcacc
      241 tttcccctta ggcaatgagc tagtaacagc ttttctcatc tcttcaggca gcattgccct
      301 aagaagatga cctaagttca aaaagaggct atcaccagcc tctcaaattg aaaaaagtcc
      361 ttagaaaata atttccaagg gcttttcttt gtataaagtc gtacaataaa agaaaaggat
      421 tgtacagtgt tatctatatt tcataaagac aaactagact ataatcgtaa ctgatacgtt
      481 ttttctatgc gctaatttct tcaacctctt taacaagata gttatgatac tatttctaga
      541 tcatcaaata tcattttcta atgttaatat ctttattata tcataaaaat gttttcaaaa
      601 acagtcttgt tttttaattt attaatgtta aacttaaatt tttgaaagac tagtctaaac
      661 atttattttt aaagaagggc atggtgaatc aatatgattt ctgtaaagaa aaatttatgt
      721 cgcttaggtg ttttgtctag tagtttatta cttttaacag ctgcaacgac tccatctgtc
      781 attgcttttg cggatattca aacaagtgcc ataaaaaata atacagatga cgcagatggt
      841 atgtattttg ttcaaagtta tgaaatgtct gtagaagata aagaattgct tgttcgaaat
      901 gttaaagcaa atcatcctac agtttctgaa gattttatca gagaagttat tgaaagacaa
      961 ttagtaggtg attatacatt acctgaagaa gagactcttt tccgctcagc atggcaaggg
     1021 gttacagtag atcaattggg agcagctcta gatgtggcta ttggtatggc attaacaggt
     1081 ggagctggat caattgctgc tggtgttttg agagtcggaa aaagagaagc tgttggtcgg
     1141 gtaaaatcaa ttctaattaa atatgggcta ggtaaaatga tagctgaaat tccagtcgat
     1201 tacatgttaa atttattatc gccaggatat catatagcta gatatattga tagtattgat
     1261 acagttccta ataataatag aattaacctt tggtaagtta ggaaatttag tactgtgaaa
     1321 aaaatttata ttttatattt tgtgctttat tgcttattat accttgtcat atcattatta
     1381 attagctatg gtatgtccca ttttcttaac atggaattta aatggtggaa taaattagct
     1441 atatctctaa catctttata tattatttat caaatgctga aaaaggataa attaattaaa
     1501 taatcaacta atgtacaagt tgtctttaag ctgaaaagag gctatcaaca gcctcttttt
     1561 ttgatgatat agataagccc aatgcttcct tagaagagct cttctgtgag atgaccttat
     1621 cacctgacat tagctgcttg gctcatgcct acagctaaag gaaatgccct gcaaggatag
     1681 cagcacttag cctgctggtc tacggcgtgt ctcagctgca cctaagccaa gcaaagattt
     1741 gtactaggct gccctgcctg acctgtggca gccctttgcc cttgacatgc agagtaccgg
     1801 gaagagagct ggctgtggag ccatcaaaag aaatggttat atgccctagc tgagcaagat
     1861 ttttttcaac aacagcacct actgctgtga tgtcatatgc catttgatca atgactagct
     1921 gaccaccagc agagatagac ccagacactt gcttgttgtc aatcgtatag caaaagtctg
     1981 ccaagtctgc cggtgctccc tgatcaaaaa gaataagcat attggcagca ctaatcatgt
     2041 ctgccgcctc cgatccaata gcggtaactc ttgtttcaaa tacttttatc atacattctc
     2101 tctcttccta tcatacgata gctccttact gatacaaacc aatacttgca atccaagcaa
     2161 caacaacccg aggaacacca tttaaaaagc gtgaataaag cacagatggc accccaacct
     2221 ctactgtctc agcattagcc tctgataaac caagcgctac tggaatgaaa tcacagccat
     2281 tttgcgtatt aatagcaaaa agtgcaggaa gagccatttg tggtggaata gtgccttttc
     2341 caatctcaac accaatgagc gttccgatga tttgactaat aaccgcacca ggtcctaaca
     2401 gcggtgataa aaatggcaac gaacagataa agccaatgat aatcaagccc caaatattac
     2461 cagccagcgg taccatgagc ttggctagcc aattaccaac accagagcct tggataaaac
     2521 caattaaaag agagacaaat gccatgaatg gcaaaatcgt attgattaag gtctggatag
     2581 cctcacgcgc cgcttggttg aagatagcaa ctaccttacc tgctcccata ccaatgcggg
     2641 caacaaagct gctttctgcg cgctgctcag taatcttttt gctagtatca tagctgctag
     2701 cctttggaac tgatgactcc ttagcactag caacatgagc ctgagcgtca ctggctgtga
     2761 tttgctcaag acctacagca gacacgtaaa tgtcctcggt aatgtactgt gccaagggac
     2821 cgcttttacc tgtcgccacg atattaatgg ttggaatgcc ttttttaggg taaataccgc
     2881 agcgtagggt gccgccacaa tccacaatag ctagggctat ctcatcatca gggattgagg
     2941 tcacaaagcc attgaccgcc tccatacctg ttagggcagc aattttatcg acaatgtcag
     3001 gcttttttcc accgccagta atatagataa atttgtgctt agcttctgtt ggtgtaatgg
     3061 ttagcggccc accatagcca ccgctcccct taacaactgt aatactgtga taagtcatca
     3121 tgctacctct cttctataat tcaatcatct tacttaatgt cacaccctgc tgcttggcca
     3181 cgtaggctgt cgtaaagtca gttacccagc caccaacaaa gttcatgatt aacccaacca
     3241 agaggtaacg aatcgccaag tccatttggc tcaagcctag cgtcttgata cctgaggcaa
     3301 tacctaacca gacaaacaat tctcccggat taatgtgtgg aaagacaccg tttgacgtat
     3361 gacaaaattg catttgagcg gcaacatagc ttggcttgta atactcgggc ataaagcgtc
     3421 ccatgctgat tgccatcgga ttacccagca taaaagctga aataaaaggc aataccatgt
     3481 agcgactgat agggttttta gcagagattt ttgccaattg attgaccctt tgatctccta
     3541 aaataccaat taaggcattc attgcaacca gcagcatcaa gaccaccggc acaatgccag
     3601 tcatccagct gacaaaggtt tcaccaccaa gctggaagag cttcataaag ccttccgcaa
     3661 atcttgttat catttccata aataaactcc tcatatgatg tacttacaag caagacaata
     3721 caaatgtact gcctgcttga taatagctgc ttgagctgga ctcaaaacag cttttatgtt
     3781 gacaaggcaa gcaatcaatc ctgcttttgg caccttactt gaagcgtgcc agcagctgct
     3841 tggcctgtag ggtccaatca aaggctgagg catattttgg tgcgtcctca tagacccctg
     3901 cctcaaccct caagaagacc tctcttgcgt cctcaatagc caagcgcagc aatttatttt
     3961 ctcgtctaat caagggattg tagcgatcaa aataatgaat atcctgaccg atataagctg
     4021 gcattggctt aaacctggct gccactgtca caccctgcat ttgcctagca tctaatacct
     4081 tacctgactg atccaaggca aacatgacaa tggttccggc cctgattttc ccggctctac
     4141 ggccaatagc aacgcgcccc tgtcgtctaa gactggcata aacagcattg aagtgcttaa
     4201 gctgtctcag acctagcaat aattgaaaaa ggtaagcaac tatgacaaat agtccaaaaa
     4261 taaccataaa actcattaaa aaactccttt ttccttggta aatgcaataa actcagcttg
     4321 actttttagg ctccttagct ccgcctgaag cttatcatcg cttgctattt tgaaaatatc
     4381 atcataaatt ttcaagagat cagcctccat ctgcgcttca accctcttgg aaatagccac
     4441 tagaaaaata aactccacca gacagtcatg ctcacgataa ggctcgtcta atagacccag
     4501 cagcaggaca gtctttgttt ccttgtcatt aatcgtatgt ggaaaggcaa tgcgattgcc
     4561 aaataaggtt gattgcaggg cctcacgctc tagcaggcgt tgaccaaact gcctgtcaac
     4621 cagctgcttt tcctcaagca gctccgccat ttcagtcagg tagtcagtgt aggccttccc
     4681 ctttgacaga cgagcaaagt gtagggtgat ggtcgccagg tttttctggt gataatgatg
     4741 taccctgcgc cattcatttt gcagccactg gtcatcaaac agatttgtga tttggagaac
     4801 aggagatttt agctgaccaa acttcagcgg cacagtggtg aatatggcaa aatagtgatc
     4861 attgtcatca ggattgaatt gctcctcaga gaattgtgag atcaacaaat caggacctag
     4921 caccttgctc aagcgacgac aaatcatatt ggcagtgcca cgacctgtcg tgcagacaac
     4981 ggcaattttt ttcactgttg gctctgtcac atgctcagcg tctttcatca tcatttcgaa
     5041 ataaagggcc aaatagctac actcagacaa ttctatggcg cagtcaaact cctctgctaa
     5101 gacctgagct gcgacaatgg ccatatcaaa ggccaagggg tatttgtatc taatttctcc
     5161 atgaaaaata tcattggcct gaacatgaaa aatcaaacga ttcaccaaga gcttcaaatg
     5221 cgtatgcaaa gcaacaaaaa gcttgtcttg gtcaatagtc accaagagac tggtcttgat
     5281 gtgctcaatc atttttgaat aaagcctgac aatgctctgt tgcagaggct tttcttgata
     5341 ggctagatcc tcgatgtatt ggatattcaa gggaaagcta ataaactggc gctcgtattg
     5401 actcagtgac agctgatagg ctagctcaat gtgatagacc agctcctcca taaaggcact
     5461 ggaatcaacc tcattgctat agtaaggaat aggatctgtc agatacctgc cctgacgcat
     5521 tcgctcaatg gttatcgcaa agctcttggt caaaagctct tggattttgc gaggaagctg
     5581 gtaggtctga tacagctcat ctagaaaaaa caagctatca ccacacaagc cctgcggctc
     5641 aaagtatttg taaacctcat gaacataaag cagccgaagg ttcaactcag tgccaacagc
     5701 ctgtatgcca tgattgggct tgccctgaat catgaccgaa taggtcctag caagagcctt
     5761 ggctgccttt aggtctttat tgatcgtgct gcgactgacg ccaatctcat cagccaaatc
     5821 atcaatgact aaagctgagg agctttgcag tagccttttt agaagataag ctacccgctt
     5881 gctagcggaa ttaaagtcac tagccttacg taaactacca gctaatatcg tctctaatct
     5941 agcataatca tagacctgca gctgcaaaaa ggcgccttgt tgggtgatgg tcgcatctcc
     6001 atctaaaatg tcattgagct gaccaatgct acttgcagcg tttgacatcg tcttttcaca
     6061 aagtcacagc ttagaaagct agcagaggag acaaaagcaa gaccttatca gctaacagca
     6121 gcatattaaa cgaacagcta gtgatactga tcctactaag catagagctc caaaagcctg
     6181 gcttaaatag tattcaaaat agaacaagag ctctcaagaa caataaccta gcgcactact
     6241 tgccttgata agcctaaccg accttgaaaa gaagcaaaaa aaagagcctc tcacgagact
     6301 ctttgttatg ttttagcaga ctagtctagc tagctctgtc attacaagcg tgcgttgagc
     6361 gctgctccta gctcttcaaa gcctggctta ccaagaaggg caaacatgtt tttcttgtaa
     6421 gcctcaacac ctggctgatc aaatggattt accccattga ggtagcctga aagggcaata
     6481 gcaagctcaa agaagtagat cgtatagcct agtgtaaatt cgtcttgctc tggaagcgtg
     6541 ataaacatat ttggcacacc accgtctgta tgggcaagaa ggacaccatc tgttgctttt
     6601 ttgttgacaa agtcaacgtc tttgccttgt aggtagccaa ggccatcaag atcctcagcc
     6661 atttctggga taatcacatt ttgacgtggc ttatccacac gaatcactgt ctcaaagagg
     6721 ttacggtagc cttcttggat aaattgacca agagaatgca ggtctgtcga gaaattagct
     6781 gaagttgggt aaataccctt ttggtccttt ccttcagact caccagccag ttgcttccac
     6841 cattcgctaa aatactgcaa tgatggctca tagtttgcca aaatttcagt tacatagcct
     6901 ttgcgataga ggatattgcg aactacagca tattggtaag cgatgttttc tgagatttta
     6961 tctgatgaca ggtccttacg agctgcattt gccccctcca tcagcgcggt aatatcagca
     7021 cccgatgctg caattggcaa caagcccaca gctgtcagca ctgaaaaacg accaccaaca
     7081 ttatctggca caacaaaggt ttcccaatga tttgcatcag cctcaacctt aacagcaccc
     7141 ttgaccttat cagtcgttgc atagatacgc ttgttggcct cttcttgacc gtacttttta
     7201 acaagtaatt ctttaaagac acgaaaggcg attgcaggct ctgttgttgt accagactta
     7261 gaaatcacgt taacagagaa atctttatct tgaacatagt ccacaagatc agcaagatag
     7321 cttgatgaga tggagttccc agcataaaga atttgtggtg ctttgcgctc ttttgctgtt
     7381 tgtaggttgg caaaatggct gttcaaaaag tcaatcgcag ccttagcacc aaggtaagag
     7441 ccaccaatac caatcacaac aagaacgtca ctgtcagcct taatcttctc agctgcttta
     7501 aggatacgag caaattcttc tttgtcatag ttttcaggta actcaagcca gcccaagaaa
     7561 tctgatccag gtccagtgcc ctgacgtagt gcctgatcag cctctgttac ctgaccttgt
     7621 aaaaagtcaa tttcatgctg tccggcaaat tgctcaagaa cctttgaata atcaaatgta
     7681 atatgtgaca ttattttact cccttaactt ttaaagtttc attagtatca taaccttttc
     7741 tattcaatat ttcaatgttt tttatttttg gggagggtgg cctgacttta acgacatgag
     7801 gatcatttct gtctaaaagc agctttgtga tgagcctagc gcttccctat ctgcttctac
     7861 tatagcttac tggggctgat ccgggtgatg tggtagcctc ttggcatagc c
//
LOCUS       DARYJX010000065         7672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYJX010000065 DARYJX010000000
VERSION     DARYJX010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(171..461)
                     /locus_tag="TU257_001894"
     CDS             complement(171..461)
                     /locus_tag="TU257_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834874.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TU257_001895"
     CDS             complement(442..834)
                     /locus_tag="TU257_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834875.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TU257_001896"
     CDS             complement(816..2105)
                     /locus_tag="TU257_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834876.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TU257_001897"
     CDS             complement(2107..2538)
                     /locus_tag="TU257_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834877.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            complement(2759..3193)
                     /locus_tag="TU257_001898"
     CDS             complement(2759..3193)
                     /locus_tag="TU257_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834878.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKITEEQQKKDLETSIAKL
                     LVHDYEGVKTIKFQGWGHSRETGSWGTTVIINESNQMSFSFSSIKTLEDIGSTRYNPN
                     TFKLVEKPETDSKPRIMDRMNEINATSLAGVTVIYSNNNQED"
     gene            3532..3618
                     /locus_tag="TU257_001899"
     CDS             3532..3618
                     /locus_tag="TU257_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0834879.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3966..6407)
                     /locus_tag="TU257_001900"
     CDS             complement(3966..6407)
                     /locus_tag="TU257_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0834880.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6407..6868)
                     /locus_tag="TU257_001901"
     CDS             complement(6407..6868)
                     /locus_tag="TU257_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL0834881.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(7038..7241)
                     /locus_tag="TU257_001902"
     CDS             complement(7038..7241)
                     /locus_tag="TU257_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL0834882.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
BASE COUNT         2173 a         1801 c         1348 g         2350 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaaa
     2581 atgagtaaaa aataaagcta aacagttttt ctataatgtt atctgttata agttaaattc
     2641 tcctgctaat aatctttcca ttaaaacaat agggacatca ttaaatttag ctttccttag
     2701 ttcgatatta taggtctgtc ttgctaactc attatagcta ctatcggata tcgccatatt
     2761 aatcctcctg attgttattt gaatagataa cagtaacacc tgcaagagag gtcgcattaa
     2821 tctcgttcat cctatccata attcttggtt tagaatcagt ttcaggtttt tctaccaatt
     2881 taaaagtatt gggattatat cttgtgcttc ctatatcttc taaagttttt atactagaaa
     2941 aagaaaaact catttgatta ctctcattaa taatcaccgt cgttccccac gaacccgttt
     3001 cacgagaatg tccccatcct tgaaatttaa tggttttaac cccttcatag tcatgaacaa
     3061 gcagcttagc aatgctggtt tccaaatcct ttttttgttg ttcttctgtg attttaccat
     3121 tcaaactaaa taccataagc aaccctccta tgagaatcat taaagcaata aaagctttgg
     3181 tcgacttttt catgaaagtt ctcctttcaa tttctaataa tagtatacaa taaatcagaa
     3241 gtcatagaat aaccatattc aatttttatg tcgtattcga taaaaaatat accatctcaa
     3301 caaacaatcg cttaaaaacg attttagggt atatttcttc cctgcaagca aaggacacaa
     3361 aaaagccatc tgaattttca acatcagaca gctatttcgt atgactatgg tataatggtt
     3421 tctgcagaaa agttaaggcg gtggctctaa tttctgaaag gtggtggtgc ttatgactgt
     3481 aagtgctaaa atccaaagag aaaggagcga atattgtccg tttacgaggc aatgcaactc
     3541 atgcttgggt tcggtagttt tctactttca ctcattggct tagttgttat tatcgtaaaa
     3601 atgagcaata aaaaataacc gtctaacttt agcgagtaac ggttattttt taactaaaaa
     3661 caagctaccg tcttaaacgg ttctgcattg ggtagttgtt ttgagcaact gtcctttttc
     3721 tattttcatt atatctcagc taagaaaaat agtcaaatga gatactattt tggcagctaa
     3781 attggtagct aaatcttcaa aatacctatt tttcgctaaa ttcgattaaa attaaatcct
     3841 atctgtctgc tacgctttaa actctcactc tagtacttca tcaccatacg acaaaaagag
     3901 cctgagaaac tttttgtctc agactctctc aaagctctta gcttaatatc aagcaaagtc
     3961 atgcattaag cgatatcaaa agctagtttt ccacgtgata caccaatctt gaggctttga
     4021 ccgcttgata actctcctga cagcattaat tctgctaacc tgtcctcaac ctctgtttgc
     4081 aaggtgcgac gaagtgggcg agcgcccatt tcaacatcgt aaccagcttc agacaagtac
     4141 ttgagagctg atggctggaa cttaaggcta atatgctttt ctgccaaggc tgcaatcagc
     4201 ggcttaacca taattttcac cacatcacgc atgttttcct gtgttaggct atggaagacc
     4261 accttttcat caattctgtt gataaattca ggccgataag cctttttcaa ttcctctaaa
     4321 atacgctttt ccattgcttg atggtcatga ccgatcgctt tagcgccaaa tccaaccgtc
     4381 ttatcatctc ttagagcagt tgctcctagg ttgctcgtca tgataataat cgtgtttgaa
     4441 aaatcaacct tacatccacg actatctgtt aacataccat catcaaggac ctgcagcagg
     4501 atattaaaga tgtctgggtg agccttttca acctcatcaa aaagaagaac ggcataaggc
     4561 ttatttctaa ccttttcggt tagctctcct ccctcatcat agccaacata gccaggagga
     4621 gccccattaa gacgggaggc tgcaaatttt tccatgtact cagacatatc aaaacgaata
     4681 agggctgact catcatcaaa gagtaattcg gccaaggcct ttgctagctc tgtttttccg
     4741 acaccagttg gaccaagaaa cataaaggag ccaatcggac gcctgcctgt gcgaatgcct
     4801 gactggttac gacgaatggc tcgtgcaata gcagaaacag ccatttcctg accaacaaca
     4861 cgcttatgca attccttttc cagattcagg tattttttac tatccgcctg agttagtttt
     4921 tctaggggaa tacctgatag cttgcttaag gtgtgtaaca tatcatcttc agtaactgct
     4981 gttggtttta gctttggttg cttatcctct ttgactaaaa gggctgacac cttgctcata
     5041 tcaccatcaa gcagggcttg atcaagcggt gttataaagt caggctgcgt ctttttaacc
     5101 atactttgca ccatcgcact ggcttcatca agcagatcaa tcgctgagtc tggaagctgc
     5161 ttacttgtca aatagcgccg agccagcttc acagcagtat ggacagctgt atcagagatt
     5221 gttacattat ggtactgttc ataggaaggc ttcaagccaa gcaaaatctg ataagcgtcc
     5281 tcaacactag gctcctcaat caatatcttg gcaaagcgac gagaaagggc tgcgtccttt
     5341 tcaatgtgct tttgatattc ctcttgagtt gtagcgccaa ccatatgcag ggtaccgcga
     5401 gaaagggctg gctttagaat attagcggca tcaagtgtgc tgtcaatacc acttcctgat
     5461 cccataatgg tatgtagctc atcgacaaac aaaatgatct taccatctgc ttcaatatcg
     5521 tcaatgagtt gattcatgcg ctcttcaaaa tccccacgaa aacgggtacc tgcaaccaca
     5581 ctcatcatgt caagctccaa gacacgcatg tcttgtaatt cataaggaat ggctccatta
     5641 gcaattcgct gcgctaagcc ataagctaga gcagtttttc cgacacccgc atcaccaaca
     5701 agaacaggat tatttttcgt cttacgacaa agcacctgaa ccatacgtga cacctctttt
     5761 tctcgtccga tgactggctc taataagccc tgtcttgcca tctctgtcag gtctcttgta
     5821 aagtctgata gctcaccagc tgtactctgt ggcttcatca tttcagaaaa ggtgcctact
     5881 gatttactct ttttaggctt acgcaactca tgaatcgcct taatagtttc cttgctatag
     5941 ccggcattta gctcaatagc cttacgtaaa tccgcaaacc taggctctcc cttgccagaa
     6001 tccttgagcc tgtagcctgc caattctaac agacgactgg ccataatatc cggattgagc
     6061 aaaatagcaa agagtacatg ctctgagcca acctcatgct cattgataac ctgacagata
     6121 gcatgagcaa atgctagtat ttctgataag gccttggatt gtggcttgaa ttggacagaa
     6181 gtcacctctt tgggactttt tcccatggct aaaatagcag cagcctcata ctcttcagcc
     6241 ctaatctttc gttcaaattc gcttaacacc atggccgcta aggaatggtc aacagctacc
     6301 atagctaata aaatatgcca ggtctcaagg taaggactat caaagcgctc tgcttgaaat
     6361 tgagcctgat taaaaatgtc ttgcatcttt aatgaataaa tcatcactaa ttgcttccct
     6421 ttctatcaat tcgttgcaat aggcgataaa gcatacgagc acgaatttct ggtgcttgat
     6481 gtcccaaaac atcattagaa gctacagcta agataatgtt tccttcgcgc tctgttaaca
     6541 gttgctcatc aaaaagcagc tgaatcgaat ctgtaaaggc ctgctcgctt aaacaatcat
     6601 caatagaagc gatcaacgta ccaatcaggt ggtgcttatc cgaaaaatga accttagcaa
     6661 tacgaatgta gccaccacca ccacgcttac tttctacctc atagcctctg ctttctgtaa
     6721 aacgggtctt gatcacataa ttaatctggc ttggtactac ttgaaaggaa tccgccagca
     6781 tggagcgctt gatctctgcg attcctgatt gggctaacaa ttctttgata tattcttcga
     6841 tactatcgga agtatttttt gttggcatgc cgtcactcct ttgctaaaac gattcatttg
     6901 ctgctttaag cctttatttg actaaaactg actaacatta tatcaaatag cagtcactaa
     6961 aagcaaatgg aaatcactag aatgtaaaag gacaggtgct atcaacaaca cccatcccct
     7021 attatctgct cactagatta agacaattta gtgatattta ctgcctgagg accgcgctgt
     7081 ccgtcttcaa catcaaacgt caccctttgt ccctcgtcta acgatctaaa gccgtcagac
     7141 tggattgctg aaaaatgtgc aaaaacatct tgaccatttt cagttgaaat aaagccaaag
     7201 cccttttcag cattaaacca cttgactgta ccttgtgcca tagtcatcca cttcctttct
     7261 ataacgcatt tgtaaacata gagagaaata aagatgccaa aacacaacta ctaattcaaa
     7321 aactaattta ctcgctcagt gtaacacgaa tggcagccac tgtcaacaca tacccctcac
     7381 aatgacagct tttctactcc acctgctaaa atgtaaaaaa gcaaagtcat gctgaccttg
     7441 ctttaacaat ctaaggcggt agacggattt tagatgcatt gatatcagtg ctttagagta
     7501 actttgaccg acttttgacc gaccgccaat ctaactccct cagcacattt tctacttttt
     7561 cctcggtcac cacttcccaa ggctgcactt tctcccctgg caacacataa tcaaatatct
     7621 gtccgttttt acgcacaatc gctactgtgt ctcctgttat atatccgtca tc
//
LOCUS       DARYJX010000066         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYJX010000066 DARYJX010000000
VERSION     DARYJX010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            436..975
                     /locus_tag="TU257_001903"
     CDS             436..975
                     /locus_tag="TU257_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834883.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TU257_001904"
     CDS             972..2087
                     /locus_tag="TU257_001904"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL0834884.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGKYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TU257_001905"
     CDS             2077..3339
                     /locus_tag="TU257_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0834885.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TU257_001906"
     CDS             3385..4404
                     /locus_tag="TU257_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0834886.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TU257_001907"
     CDS             4603..5313
                     /locus_tag="TU257_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834887.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TU257_001908"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TU257_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL0834888.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TU257_001909"
     CDS             6662..7471
                     /locus_tag="TU257_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0834889.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2020 a         1599 c         1798 g         2078 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaaag tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt acaggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYJX010000067         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYJX010000067 DARYJX010000000
VERSION     DARYJX010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(25..486)
                     /locus_tag="TU257_001910"
     CDS             complement(25..486)
                     /locus_tag="TU257_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL0834890.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TU257_001911"
     CDS             complement(530..1606)
                     /locus_tag="TU257_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0834891.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU257_001912"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU257_001912"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL0834892.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TU257_001913"
     CDS             4915..5859
                     /locus_tag="TU257_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL0834893.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            complement(5884..6021)
                     /locus_tag="TU257_001914"
     CDS             complement(5884..6021)
                     /locus_tag="TU257_001914"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834894.1"
                     /translation="MAADMLRLIIRSSSSSYRYLLGRLFALAVVVPALADELSTGRAQ
                     E"
     gene            6118..6768
                     /locus_tag="TU257_001915"
     CDS             6118..6768
                     /locus_tag="TU257_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL0834895.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1998 a         1792 c         1334 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attaccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYJX010000068         6819 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYJX010000068 DARYJX010000000
VERSION     DARYJX010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6819
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(46..363)
                     /locus_tag="TU257_001916"
     CDS             complement(46..363)
                     /locus_tag="TU257_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834896.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(345..1634)
                     /locus_tag="TU257_001917"
     CDS             complement(345..1634)
                     /locus_tag="TU257_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834897.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(1636..2079)
                     /locus_tag="TU257_001918"
     CDS             complement(1636..2079)
                     /locus_tag="TU257_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834898.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(2444..5995)
                     /gene="smc"
                     /locus_tag="TU257_001919"
     CDS             complement(2444..5995)
                     /gene="smc"
                     /locus_tag="TU257_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL0834899.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            complement(5996..6688)
                     /locus_tag="TU257_001920"
     CDS             complement(5996..6688)
                     /locus_tag="TU257_001920"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL0834900.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         1818 a         1697 c         1267 g         2037 t
ORIGIN      
        1 tacaagatgc taaattgcaa gtaaaagtta gtcatcctat agaaattatc cgagtgactt
       61 gttgttcaaa attttcccca attttaaaaa gagatgaaac tctgcgttgg attgatcctt
      121 taagcgaccc aattcattga aaaaatctga tgcagcattg gcagataggt ctaaacgctt
      181 caaaaaaaca ctcatcttct ggtactcaga gttgatcaaa tcatttaaga catgtcttct
      241 ttcagataag ctgtcttcac gcttctgata ggctcttttc tggcgtagaa agtcctgctc
      301 ggcatcatcc atctcccgaa gcttacgata aatagccact tcctctacaa ttctgtctgc
      361 catgctctaa actctcctgc taactgacga tccgtttcaa gcttgctatc aataaccgtc
      421 tgaatatctc tattcaagtt ttcaaagtct gtggccaagg ctgacagctt gctgaccttg
      481 gattgagtat agtcctgaaa gtcttggaca aagcggtcat atgtgatacc ataagaagca
      541 aataaggcct gcacctcata gtagggcagc tcatgaaaag agttgaagtc aatcgccgac
      601 cacacttcca taagctttgc gtctgcaacc gttttatgat ccagagcttc atcagccccc
      661 tctcgagcag ccttagccat ggacgagcct aggatcattc cctgtgccgc atctaaaaag
      721 agctcctcag aactactgat ccccttgccg gtagactgcc agtgtttttt gagctgattg
      781 tagcttgaca tgctcttttt tgaggcaagg acagttaaat aggcccgact cacaaggtat
      841 tgtgttccaa tgagcttacc gtctctatct acaatctgac ccttttgatt aaaacgataa
      901 gctcctaaat cgtgataata caaggggttg gctgataaga gcatagcatc gacattccga
      961 gaaatagcta aatcatcagt tccaaaatag gcaccaaaat tgccaatgcc atcaaaatta
     1021 atgcggaaat tattgtacat attgctatta gccttaaccc atgtgatagc ttcagctgac
     1081 atgccgcgaa cagggtctgg accattaaag gttgttgctg ggatcttatg ttctgcggca
     1141 actattagtg ctagataagc tccgagagag tgacctgtgg ttgttaaggc agaatgaggg
     1201 tactttcttt tgacctgttg ataaaacttt tgagcagatc gtaattggtt ttcggcaata
     1261 acaaaattgc caccatcaat attgccgctg actaaatcat cttgattgcc ccgaatgagc
     1321 agctgccaat ccgtatcaag atctctggaa tccgcagcat ttgtccctgc ataggcaatc
     1381 acaacctgag aggtatcgat atcaccttta acaatagggg ctacagccat tgcctgcata
     1441 ccgttgtcat tggttttatg ggcatcgttg ttattgtcct gaactaagag gactcggtat
     1501 tgtcgtttag tgataggatc ttttacagtt ttaccagcaa caataacaag gtctccattt
     1561 gatttagctt tgctaggttc gacattataa acctgtttag ccaactcatt ataactacta
     1621 tccgatatcg ccatattaat cctcctgatt gtcctttgaa taaatgacag taacacctac
     1681 aagagatgtt ttattaatct tgtcaatcct atccataatt cttggtttgg tatcagtttc
     1741 aggcttttcc atcttttctg tatcatcatc agtaacaatt cctcgtattt tctcaagact
     1801 agacaagcca tcaaacgaaa agcctatttc attttctcca tttataatca ctatcgttcc
     1861 ccacgaacct gtttcccgag aatgtcccca gcctgtaaac ttaacttctt taaccccttc
     1921 atagtcatga accagcagct tagcaatact ggtttccaag tccctttttt gttgttcctc
     1981 tgttcttttg ccattcaaac gaaaaaccat tatgatcgct cctattacta ttattaagcc
     2041 tagccatagc ctttgcttat tggtcttaac tgtcatcatg tcctcctttc actcttttgc
     2101 tatgcgtccg tcactctaag gaaggcagca tgactaatta gggtgaaatc aacgccaaat
     2161 cttatttata ttattctcat tttgtaatta aattataata tacagacatc tacttgtcaa
     2221 tatattatgt ccttagttac ttttttggta tattttaatc aaaacaagcc gtactaagtt
     2281 ccaggagcat gtcaaaaaca gcagcttact gctagccaat ccttgtgctt tgtcctttgg
     2341 aaagccaaaa aacctaccat gacgataggt ttttttatag cttattcttg gttatcatct
     2401 gctacatgta gaaatacagc taaaactaag ctctgtccta gagttatgac aagtaagtca
     2461 gatcctgcgt atccttgagc ttaacagata ctaccttaga aacaccagat tcttgcatgg
     2521 taatcccata aatactgtct gctgctgcca ttgtcccctt gcggtgggta accacgataa
     2581 actgactatc cttgtcaaaa cgattgagat aatctccaaa acgcttgaca ttggcctcat
     2641 caagggccgc ctcaacctca tctaaaatca caaagggaat ggtcttaatg cggataatag
     2701 caaataaaag ggctagcgct gataaggctt tttctccgcc agacatcaca ttcaaagatt
     2761 gaagcttttt accaggcggt tgcactgaaa tatctactcc agcagaaagc agatcagtct
     2821 ctgtcaacat caagtccgct gagcccccgc caaacatctg cctaaaggtc tccttaaagc
     2881 tatcacgaat agcctcaaag gtaaccctaa agcgtgcctt aacctcatgg tccatattgc
     2941 caatcgtatc taccaagaga ttcttggcct tgataaggtc agccctttga ccatttaaga
     3001 aggccaaacg ctcactaacc tcatcaaatt gagcaatagc atcactattg attgggccta
     3061 gggcacgaat gctttgctga acctgctgca atttctgtct tgctgctgcc atgtcagtgt
     3121 cattgattgg gcttgcctgc tccttggcct cctctaagct tagctgaagc tcctctgata
     3181 ggcttctagc gtgctgccgc aaacgaccaa taacctgctc taagtcagcc tccagtcttg
     3241 cctgctgacg aatgaacgct tcatttttct tggcttcctt aagcaattga gcctctagct
     3301 cctccagtct ggcgtcatag tcctcacctt caaagcgcag ctgaatgaag cgctcctgag
     3361 tcttgatctt gtcttgatta gcctctgtca gctgattttc taggtgaggc aattggtcaa
     3421 tggcctcctg actaacctga tgtgataaaa cagtctccaa attagctaat tccttctgac
     3481 cctgagcaat catcgtctcc aagcgacgct ggttagctgc ttcaaacttt ttctcgttga
     3541 gcaaatctcg ctctttaaga cgagcctgag ataattcctg gctaagctgg tccttctttt
     3601 gcttaatcgt atctttattt tccttaattt gctcaatttc tgacgttaag gctgattttt
     3661 catcagctag gagctgcaat gcctcctcca gcctcgcttt ttctgataat aagcgctcac
     3721 tagactgacc agtctgacgg ttgctgagaa gctctagcag ctcttttgag tcagccagct
     3781 tttctgctag ctgctgatag gccaattgtg ttttttgctc gaccagtctt gcttgctcac
     3841 cagccagctt agtatcagcc tgcgcagcct ttttagcctt caaatcagcc tgtacagcag
     3901 ctactgcttt ttcagattcc ttgatctgct cagaaagcaa ggctaattcc ttctcaatct
     3961 gctctagctc tggcttgata aaggttgtgc tattgtgacg attagtcccc cctgaaaagg
     4021 caccaccggg acgcagctcg gtaccatcaa gcgttacaat cctgacctta taatgcagct
     4081 gcttagctgc ctgattagca tgatcaatgg tatcaaaaat agccgtcaca cctaacaggc
     4141 tttgtacaat agcgaccaaa gagggctcat aggtcaccaa agaatcagct gtgcctaaat
     4201 agccctgaca agccctgagc tgcttgagag tcacctcaga aagctgacgg gccttaatcg
     4261 ttgtcagagg taaaaaggtc gcacgcccct gacgattagc ctttaaaaag gctatcgctc
     4321 gcttggctgc tgcctcatct gccacgataa tatgctgact actagctccc aaagcaatct
     4381 caagtgccgt ttgatactga ctatcaaagg tcaaatgctc actaactgct cctaaaatac
     4441 catctagctt accagcagcc tgaagcactg ccctaacacc tgcgtaaaat tgactatgat
     4501 ttttttggat agaaaccaaa ctagccctac gagcctcctt ggcttttttc tgatccaaca
     4561 aatcaaaaag ccttgtctgt ccctgatgat aatcctgctc caaggcctca actgtctttg
     4621 ctagctcttg ataatcagct aggagctgct caagtcttga ttgactagct tgataagcca
     4681 aaagagcagt ctgggtgtcc tgactgagct gattgacctt ctcttgtagg acttggtatt
     4741 cctgcgcctg actggctttc gcctgacttt ccttatccag ctgcgctaca atagcggtta
     4801 attggtttga cacatcagcc tcttgctgga gcagaccaac aaaatcctca cgaagagcct
     4861 caagcagctg atctggatcg ctagaaaatc gctcaagctc ctgagaaagc tcgctgacct
     4921 tggtattaaa ctcagctaag gcttgatgga tttcatctag ctgacgactc ttttgctgat
     4981 gctcctgttg aaaggcaagc aattgctcct gagcctgctg cctgcgctga ctggcttctg
     5041 ttttcttttc ctgcttttga ctaaggtcca gcttgatgag gtcaatctgt cgctccagat
     5101 ctgatatgac ctttgtcaat tctagcaaat cagcctgcgt ctgctcagct acagcagaga
     5161 gcttttgccg cttggttttt agacggtgat tttccgcctc tagactctga cgcttcctat
     5221 gataggccgc tagatcctca cgaagagcta ctaaggcctt ttcttgagcc tcctgctcca
     5281 tgcggtcttg ctctatatcc ttgaccaaaa tatccagctg cagctgctta cgatcagcat
     5341 ctaaggctaa aaattgccta gcagttttcg cctgtctttc tagaggacca gcttgatgct
     5401 caagctcata gataatatcg tctaagcggt caagattatc ttgagtttgg tttagcttag
     5461 tttgcgtctc cttcttgcgg gtcttgtatt tcaaaactcc agctgcctct tcaaagatgg
     5521 cccgtctttc ctctggctta ctattgaaaa tctcctcaac acgaccttga gaaataatag
     5581 agaacgaatc gcgccctagt cctgtatcca taaacagctc gtgaatatct cttagcctaa
     5641 cttttttgcc atcaatcaga taatcactgt cgccattgcg atagatatgc ctctccacac
     5701 gaatctcttt ctgagcattc ttaataaagg catctgaatt atccaagaca acagccacct
     5761 ctgcataatt caagggactc cgatgctcag ttccagcaaa gatcacatct ggcatcttgc
     5821 caccgcgcag gcttttggca ctggcctcac caagtgccca acgaaggctt tctgtcacat
     5881 tactttttcc agagccattt ggccctacaa cagctgtgac ccccttatca aagataatct
     5941 tggtcttatc tgcaaaagac ttaaagccct gcatttgtat ttcttttaaa aacatttaga
     6001 cctcactaag ttgggccagg gcatttttag cagcgtcctg ctctgccagt tttttagatc
     6061 tacctgtccc cttgctaaga tgatcctcac caaccaatac agctacctca aattgcttag
     6121 catgagctgg tccagtctcg ctaatcacct gataatcaat cacaacatca cccttagcct
     6181 gtaacaactc ctgcaagcag gttttataat ccttgacctt ctcaaaagtt ccctgctcaa
     6241 cctgtggaat cataacctga tttaaaaagc gacgaacctc ttcaatgcct ttatccaaaa
     6301 gaagagcacc caaaaaagcc tcgaacaaat cgcctaaaat cgtatcacga tgacggcctc
     6361 ctgatttttc ctcgcccctg ccaagcttaa tataagcatc aaacgaacaa tagcgtgaaa
     6421 agcctgctaa gctttcctct ctgacaatcg ttgatctgag ttttgacata tcaccctcag
     6481 tctgcttagg atacttggca aagaggtatt ctgaaataat taactgtaga acggcgtctc
     6541 ctaaaaattc caaacgctca ttatgtgaaa tgtttaggag gcgatgctca ttagcataag
     6601 aggtatgtgt aaaggcagtc tctagtaatc ttttatcatc aaaacggata ttaaaagagt
     6661 tttccagcag ggcctcaagc tttttcatca tgacaaatct ccttttctaa tgtccttata
     6721 aaccattcta ttataacaaa aatccacttg aaaggcttat cacaagtgga tttttcagaa
     6781 atattgtacc aaataggcac gagctattga ctgctgcta
//
LOCUS       DARYJX010000069         6155 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYJX010000069 DARYJX010000000
VERSION     DARYJX010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6155
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(1017..1328)
                     /locus_tag="TU257_001921"
     CDS             complement(1017..1328)
                     /locus_tag="TU257_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL0834901.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
     gene            complement(1578..2111)
                     /locus_tag="TU257_001922"
     CDS             complement(1578..2111)
                     /locus_tag="TU257_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL0834902.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            complement(2344..3120)
                     /gene="recX"
                     /locus_tag="TU257_001923"
     CDS             complement(2344..3120)
                     /gene="recX"
                     /locus_tag="TU257_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL0834903.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            complement(3269..4435)
                     /locus_tag="TU257_001924"
     CDS             complement(3269..4435)
                     /locus_tag="TU257_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL0834904.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWEIYVDNRLKAGVWSPDTYVERTNIFK
                     NHIGPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKIARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVNFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVSENVTAAFMGSIK"
     gene            complement(4639..5181)
                     /locus_tag="TU257_001925"
     CDS             complement(4639..5181)
                     /locus_tag="TU257_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEL0834905.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            complement(5207..5992)
                     /locus_tag="TU257_001926"
     CDS             complement(5207..5992)
                     /locus_tag="TU257_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834906.1"
                     /translation="MNDKELALYIGSKIKELRKNKGLTQKELAILVNMGDTTIANYEK
                     GFRTPKKNTLFKLANALSVTIDELFPPINKKNKENIVHLKQQSNTTEINNKVALLDKE
                     LKEPRHSYWVKYGENLLSEQNTVGHSKNTVEEPQAAYYTYNYYDHAASAGTGQYLSDV
                     QVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFVKLSVELTDGDIGVFEYYGDAYI
                     KQLLINDEGAFLHSLNSKYEDIPVDRDSDFRIIGEVVGSYSEK"
BASE COUNT         1721 a         1083 c         1150 g         2201 t
ORIGIN      
        1 ctaacgtcta aagaggacca gattggtgct cttttttgtg atgttaaaac caaaaggagt
       61 ttgagcaagg ctcactttag aactggcttt ccactgaaag cagtgttttt tgagttgaag
      121 cagtgttgga aagctttggc aatcgaagat agggatttta gaggcttttt ggaagtcttg
      181 tttgctcatg tttcctttgt agtgagggca taagagaact gaataatcaa gcttaggatt
      241 gataacgatg tgggggtgag cttttagaac agtcaacggt tggatattgt tttttaaatg
      301 ctgagtaatg cttaaggtgt tcctatgagt ctttctaatg atggtttgat tgcatttcat
      361 gataagtcat atgggcttgt ttttgtacaa ttaaaaaaac tataatttcc acagtgggct
      421 taccgactac agagattata gagctttttg agggagggca aagtttttgt actttaaagt
      481 gtgtttgttg atttttaggt tctataagtt ttgtgcagtt aaaactactt ttaagattac
      541 ggggtatgtg aagatcctat gtgaggctaa cacaaagcaa ttagcttcct actagccatt
      601 tggtcatata gaatttaatc gttatgacaa tgatgccaat tgtcataaag cctatagtga
      661 ttgtcgtaaa atgagatgat aacatatcaa aatgtcagac cctatagata tagctcaata
      721 tgatgggact attgggatgt tctatcaaga tttccatttc ccagaatagg aaatagggct
      781 taggtgatgt gtttgcttag caatgattta cagaatgaaa aaactgtcaa gctcatgtta
      841 ggactatttc taccggcatg agcttagttt attgctatgt atctggctga ctgaatatct
      901 atacagcatt cagagctagg ataaagacac aagattatct catgttggtg cttgtagcag
      961 atgtgatgag ctacaactga atggtaagga ctttatagct gatgtccgag gtcttatcaa
     1021 tacatctcgt gaggcaataa aatcgtttca attccttgct ggtttacgat atagagcgtt
     1081 ttggggtaaa aggcgttaaa tggtgtgtta tagtcaaaaa caatccgaag cccagcttgt
     1141 tgatcaatgt actcataaga aaggtttttt ttatttttaa ttagcctgaa ggtgagaaca
     1201 gtattgaggg gaaacacccc ttttaggtaa tggtcaatga tttcccagaa ggtatcaatc
     1261 agctcaggtg gaaggctgac tgcaacgcca aagcttgcgt atcgtccttt tgttgcttga
     1321 aatgccattg tcaatccttt ctattgttat ggtgttataa tgaggtcatt tgaatgcctg
     1381 atctagctag gcagctgatg ataaatactg attgctactt ggtgttatag gctgtctgtg
     1441 cttgtgccaa gctatagtgg ttaatgatat gaatttgaca acaaatgctg atagattgca
     1501 agtgccagtc cagtttacag ctgtgatact atactagcga ttaaataaag caccctcggt
     1561 ggagtgctag acaacgacta acgattcttc agttcaagat aacgtttgta ccaaatactg
     1621 acataggctt ttgaaaatgg tcctttttct ttattgatcc agtcgactaa tagcttgaca
     1681 ttctctttta aaataaaatc cagattaggt gaataatgca tttcttgctt gtgcatttca
     1741 tattcgtcta catcaagcaa tctcttttca ccatctgcaa agactttgac atcaagatca
     1801 tagtcaatat acttgagcgc ttctgcgtcc atcaggtatg gacttgcaag gttgcaataa
     1861 taggaaacac cattatctcg aatcattgct ataatattga accagtattt tttatgaaaa
     1921 taaacaatcg caggctctcg tgtcacccat cgcctgccgt cgctttcagt aacaagtgtg
     1981 tgatcattaa ctccaatcag agcattttca gttgttttta gtaccatagt atcgcgccag
     2041 gttcggtgca atctaccatc atgcttataa ctttgaattg taataaagtc gccttcttta
     2101 ggtaatttca tgccttacca actttctaca attaaactta tcctctatag tttaccataa
     2161 ttgagaaaat aaatcactgt tttggacaat atgatctgac aaatgcttaa agaagttttt
     2221 agaaatctga tgttcagttg aggagctagc taaaccatta tcaaagctac aggatcataa
     2281 taggactact ttgttgctga ctaaaagctt ttgcgtcaaa tcggtgcagc agccttggta
     2341 gaattagaaa tagtcattta gcttagtggt aatatcatca ctgtcatagc ccttgcggta
     2401 aagggcttgg taaagctttt gcttcaactg atagccatca tagcgacgac tgtattttcg
     2461 taatagcttg tcgaattcct gatcaagcag gtcttcgatg tgctgactat cctgctcaag
     2521 gcttagttga ctgacaatgc ctttggcaag gtcataggaa aagcccttgt taagaagtcc
     2581 ttgtatgatt ttatcggtca aggccttact tggcaatttg tgttgatatt tctggtagat
     2641 tttttcagca gccttttgtg ctatagagga aaaatcagtc tgtgctagga caggctcaat
     2701 gagttgtgag gctattccct tgagcattag cttttgcttg agaagtaatg gtcccttgtc
     2761 tccagtaagg ctattttggc gtatataggt gtcaacgtat tgctgatcat caatccattt
     2821 gccttgtttt aggctatcaa taatgcttgg aatgagatca ggactaatct gatgctttag
     2881 caggtaatct tggacttgct tttggctcct ttgttggaag gcaataaaac ctaaggcctt
     2941 gcttttacca tatgagaatt gtgcgaagct tttgatgtcc tcccattgtt ggctgtctat
     3001 gaccatgtgc ttacttagca taaatgtgac aatcgtatct tctgtgaccg ttaggctatc
     3061 accattgtct agcttaatga ggtataaatg ctttttcttt tcaatttgac tgattttcat
     3121 accctcatta taatgtttta aaatttatat acaagcaaat tgttttaaaa cgttgatatt
     3181 acagcatttt agtttttttc gtttagtcat aaaaagtaac aaaaatcata aaaagtaata
     3241 ttttgtcggg gactatgtcg gggaattttt attttatact gcccataaaa gctgctgtga
     3301 cattttcact tacctcgtct tttatgtggg tgtattggct agtcatgtaa ttatttgaat
     3361 gacctaaagc cgctgccata tgctcaattg ggacaccggc tatttggccc tgtgtagcga
     3421 aaaaatgcct catcatgtgc ggagtaaaat taacgtcgca atttttattg atttttttaa
     3481 ataagcagta gatgtagtgg ctaccgattg gttttcctac aaaagatggc tttacttttt
     3541 cgtcgtctcc taaaaatagg aaatcagcct tgtttaagat gcgatcgttg cacacggcta
     3601 ttttgataga tgtatcaatg gcttttttta gcagttgtga tgtctcgaaa tctaaataca
     3661 catatcgttc cgaataagct gtctttaggc ctccgccatc ttttctacct ctggtccttg
     3721 attcgtctat ctttacgact gcacaatctt tatcattaaa agttatattc cctaatttta
     3781 tgccagctac ctcgcttcta cgcaatccaa gatatgttat cctaaccatt gcgtagtcat
     3841 aatcatcaag catttttctg gcaattttat cccaagcttt aaactcttgc attgatctac
     3901 gtttgttgat aggttttatt tcgctatcgc caatgtcaat aaatttgatg atattatcgt
     3961 ctagcatttt atttttgaca gcatgattta acataatact aaaaacatca tatatgtgct
     4021 ttactgtact tcttgagttg gtattgagca gattgttaat gtagttttcg tattctatac
     4081 ggtttatagc attcattttt ttattgccaa actttgggcc gatgtgattt ttaaagatat
     4141 tagtgcgctc aacgtatgtg tcaggagacc acactccagc ttttaatcta ttatcaacgt
     4201 atatttccca gtactgatca actgtcaaat ttttgttata agcaaaatca ttgttttcta
     4261 ttttttgctc aatttcagta agtgcagctc tggcttcctg tagcgttttt aagttgcttt
     4321 ttgtagcctc tttcttttta ccttttaagt aataacccct acggacgtag tagcgtttac
     4381 ctttctttgt atcgtaggta aagatatttg ggtattttgt tttgttgtat ttcattctta
     4441 aatcctttcg tttttttgac ttttggacga ggtcgtttga aaggatattg gcatcaccac
     4501 ctttgtgtga tataatttta ggtacaagaa aacgaccttt ttaatggttg tttcttatac
     4561 ggtttcgcct cacgctcaga ctcgccaaag tttgagagcg tggggctttt tttatttttt
     4621 aacggttaac tttacacctt aaattcctaa aattattttt ttcttagcta taaactcttc
     4681 ctctgtaaga atgccttcat cataaagttt tttaaactta cggatttcag caacggcatc
     4741 ttccgagcct acagttgctg ttttctgagg cgattgatgt tggtacagat tatatttgta
     4801 ttgttctaca caatctttta ttttttcggt aagtacaggg caagtgtcct tggcaatatt
     4861 agatatttca atttttgtgg ctccgttcat aacagctatt gcgccaagaa ttaaaccttt
     4921 agagtatgag acgctattaa ccatatcaag aggaatttct gtcgatctaa ttccatataa
     4981 cattccctta tcgataaata aaattcgttt ttgggtcaat acaacaagga cagtattgcc
     5041 gtttacaaac ccagatgttg cgtattggat aatttcgtca tctgacaaaa tttctggcaa
     5101 agcctttact tctttctttg tcccccaagt gtcgtaagcc ccacattcct tcatttgttg
     5161 caaaacagta tctaaattca taataaaact ccttataaaa atattcttat ttttcagaat
     5221 aactccccac aacttcacca ataattctaa agtcgctatc tctatctacg ggtatatctt
     5281 catacttgct atttaaactg tgcagaaatg ccccctcgtc atttataagt agctgtttga
     5341 tataagcgtc accataatac tcaaaaacgc ctatatcgcc atctgttagc tctacggata
     5401 gcttaacaaa gacatagtcc ccagagtgat attcgggttc catggaatct ccataaacag
     5461 gaataacaaa atcagcgtca taatcaactg gtaattcaat tgtttctact tgcacatcac
     5521 ttaaatattg accagtacca gcagaagcag cgtggtcgta gtagttgtag gtgtagtagg
     5581 cggcttgtgg ttcttctact gtattcttac tgtgtcctac tgtgttttgt tcagataaaa
     5641 gattttcacc gtattttacc caataactat gacgaggttc tttgagctct ttgtctaata
     5701 aagcgacttt gttattaatt tctgtggtgt tagattgctg tttaagatgt acgatatttt
     5761 ctttattttt tttatttata ggagggaaga gttcatctat agtaacagat agggcattcg
     5821 caagtttaaa caaagtattt tttttaggcg ttctaaaccc cttttcatag ttagcaattg
     5881 tagtatcccc catattaacc aagattgcta actctttttg agttagccct ttattttttc
     5941 tcagttcctt gattttagag ccgatatata aagctagctc tttatcattc atttgaattc
     6001 ttctttcttt ttatttaata atagtataac acataaattc acgttttgaa aagttttttt
     6061 gttttttcga aaaaaaacag ttgacacttc acgaaaagtg aagtacaata taatcaagct
     6121 taaggaatta agcaaaataa aaactcccaa gaggg
//
LOCUS       DARYJX010000070         5468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYJX010000070 DARYJX010000000
VERSION     DARYJX010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            227..1780
                     /locus_tag="TU257_001927"
     rRNA            227..1780
                     /locus_tag="TU257_001927"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2002..2074
                     /locus_tag="TU257_001928"
     tRNA            2002..2074
                     /locus_tag="TU257_001928"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2035..2037,aa:Ala,seq:tgc)
     gene            2382..5281
                     /locus_tag="TU257_001929"
     rRNA            2382..5281
                     /locus_tag="TU257_001929"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5366..>5468
                     /gene="rrf"
                     /locus_tag="TU257_001930"
     rRNA            5366..>5468
                     /gene="rrf"
                     /locus_tag="TU257_001930"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1577 a         1102 c         1576 g         1213 t
ORIGIN      
        1 tcgtatacta gtgaagctgt cggcgagcac tagctcaagt taatgaaaaa aaggtaaaaa
       61 aagtagttga caaaggcagt ctaagctgat agaatgtaat agttgtctcg tgagacaaag
      121 acctttgaga actgaataag acgacctaaa cgtgcgggtt acggaagtaa cctgtcaata
      181 aagaaacaag tcagtaatga cgtcgagtta agagctcaaa cactgaatta acgagagttt
      241 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtgg aacgcacaga
      301 tgatacgtag cttgctacaa ttatctgtga gtcgcgaacg ggtgagtaac gcgtaggtaa
      361 cctagcttat agcgggggat aactattgga aacgatagct aataccgcat aaaagtggtt
      421 gacccatgtt aaccatttaa aaggagcaac agctccacta tgagatggac ctgcgttgta
      481 ttagctagtt ggtagggtaa aggcctacca aggcgacgat acatagccga cctgagaggg
      541 tgaacggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      601 atcttcggca atggggggaa ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg
      661 gatcgtaaag ctctgttgtt agagaagaac agtgatggga gtggaaagtc catcatgtga
      721 cggtaactaa ccagaaaggg acggctaact acgtgccagc agccgcggta atacgtaggt
      781 cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggtttg ataagtctga
      841 agttaaaggc agtggcttaa ccattgtatg ctttggaaac tgttaaactt gagtgcagaa
      901 ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccggt
      961 ggcgaaagcg gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac
     1021 aggattagat accctggtag tccacgccgt aaacgctgag tgctaggtgt taggcccttt
     1081 ccggggctta gtgccggagc taacgcatta agcactccgc ctggggagta cgaccgcaag
     1141 gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc
     1201 gaagcaacgc gaagaacctt accaggtctt gacatcccga tgctattctt agagataaga
     1261 agttacttcg gtacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga
     1321 tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attaagttgg
     1381 gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc
     1441 atgcccctta tgacctgggc tacacacgtg ctacaatggt tggtacaacg agtcgcaagc
     1501 cggtgacggc aagctaatct ctgaaagcca atctcagttc ggattgtagg ctgcaactcg
     1561 cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg aatacgttcc
     1621 cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga agtcggtgag
     1681 gtaaccgtta aggagccagc cgcctaaggt gggatagatg attggggtga agtcgtaaca
     1741 aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaaa aggaagcacg
     1801 tttagcgtct tatttagttt tgagaggtct tgaaataagt catgagaacg ttaagaaacc
     1861 cgtatgacaa tagggaactg acgcagagtc gtaggactca aggaagtgat tctttttcac
     1921 tagggtttta gttcgaatac agtttggctt catacagacc attgataaga gtatacatat
     1981 acaagtacat ttatagtgta cggggcctta gctcagctgg gagagcgcct gctttgcacg
     2041 caggaggtca gcggttcgat cccgctaggc tccattatct aggatacaaa gagaagtttg
     2101 ggttacctaa ttttctgtat tctaagatat ataagatata gttcaagtaa ttgaacacga
     2161 cctcattttt taggaaaaaa gataaatctc ctcgtgtgta aagcacacat cgtcgatttc
     2221 ctatttttct acaaaaatgc ccaacaagtt gggacggtct tagtatctta atcttgtcca
     2281 ttgaaaattg aataactata tcatattccg caatcaaaaa agattgtaag aaagtaacaa
     2341 gaaataaacc gaaacgctgt gataacgagt ttaaaaaata aggttaagtt aataagggcg
     2401 cacggtggat gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt
     2461 ggggagctgt aagtaagcaa agatccagag atgtccgaat gggggaaccc actagctaat
     2521 ggctagtatc cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta
     2581 agtagctgca ggaagagaaa gcaaacgcga ttgcctgagt agcggcgagc gaaaaggcag
     2641 gagggcaaac cgaagagttt actcttcggg gttgtaggac tgcgctgtgg gacgacaaga
     2701 ttatagaaga aggccttggg aagggtcgcc aaagagagta atagcctcgt attcgaaata
     2761 gtctttaacc ctagcagtat cctgagtacg gcgagacacg aggaatctcg tcggaatctg
     2821 ggaggaccat ctcctaaccc taaatactca ctagtgaccg atagtgaacc agtaccgtga
     2881 gggaaaggtg aaaagcaccc cgggagggga gtgaaagaga acctgaaacc gtgtgcctac
     2941 aagaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
     3001 acgtttatgt gcgaggttaa gttgaagaga cggagccgaa gggaaaccga gtcttaatag
     3061 ggcgtaagta cgtggacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     3121 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     3181 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     3241 agggctagcg tcgatatgaa gtctcttgga ggtagagcac tgtttgggtg aggggtccat
     3301 cccggattac caatctcaga taaactccga atgccaatga gatatgatcg gcagtcagac
     3361 tgcgagtgct aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtcccc
     3421 aaataactgt taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag
     3481 aagcagctat tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa
     3541 aatgtaccgg ggctaaaaca gtttaccgaa gctgtggatt accgttaagg taatggtagg
     3601 agagcgttct atgtgtgatg aaggtatact gtgaagagtg ctggaacgca tagaagtgag
     3661 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggatt
     3721 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaagggtgta
     3781 tccgatggac aacaggttga tattcctgta ctagagtata tagtgatgga gggacgcagt
     3841 aggctaacta aaccggacga ctggaagagt ccggctaagc agtgaggtgt gatgtgagtc
     3901 aaatgcttac atctataaca ttgagctgtg aaggggagcg aagttaagta gcgaagttag
     3961 agacgtcaca ctgccaagaa aagcttctag cgatacgtat actctacccg taccgcaaac
     4021 cgacacaggt agtcgaggcg agtagcctca ggtgatcgag agaactctcg ttaaggaact
     4081 cggcaaaatg gccccgtaac ttcgggagaa ggggcgctga ctgaaggtca gccgcagtga
     4141 ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta
     4201 tagggggtga cgcctgcccg gtgctggaag gttaagagga gtgcttagcg caagcgaagg
     4261 tatgaattga agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat
     4321 tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac
     4381 gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa
     4441 agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat gtacaggata
     4501 ggtaggagcc atagaagtcg ggacgccagt ttcgatggag gcgatgttgg gatactaccc
     4561 ttgtgttatg gctactctaa cccggatagg tgatccctat cggagacagt gtctgacggg
     4621 cagtttgact ggggcggtcg cctcctaaaa tgtaacggag gcgcccaaag gttccctcag
     4681 attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg cgagagcaac
     4741 acctcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgtatg gaagggccat
     4801 cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat
     4861 cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc
     4921 caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag
     4981 acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg
     5041 agaggaccag agtggactta ccgctggtgt accagttgtc tcgccagagg catagctggg
     5101 tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc tcctcaagat
     5161 gagatttccc ataacgttaa gttagtaaga gccctgagag atgatcaggt agataggtta
     5221 ggagtggacg tgtggtgaca catggagcgg actaatacta atagctcgag gacttatcca
     5281 aaagatgaaa ccagtcgcta ttgacagctt aaggaattct tgttagacta tagttattca
     5341 attttgagtg gagaagactc gtaagttaag tgacgatagc ctaggagata cacctgtacc
     5401 catgccgaac acagtagtta agccctagaa cgcctgaagt agttgggggt tgccccctgt
     5461 gagatacg
//
LOCUS       DARYJX010000071         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYJX010000071 DARYJX010000000
VERSION     DARYJX010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(150..389)
                     /locus_tag="TU257_001931"
     CDS             complement(150..389)
                     /locus_tag="TU257_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL0834907.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TU257_001932"
     CDS             complement(548..1036)
                     /locus_tag="TU257_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0834908.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TU257_001933"
     CDS             complement(1055..1345)
                     /locus_tag="TU257_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL0834909.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TU257_001934"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TU257_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL0834910.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TU257_001935"
     CDS             4640..>5325
                     /locus_tag="TU257_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL0834911.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYJX010000072         4591 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYJX010000072 DARYJX010000000
VERSION     DARYJX010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..406
                     /locus_tag="TU257_001936"
     CDS             <1..406
                     /locus_tag="TU257_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0834912.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            415..1086
                     /locus_tag="TU257_001937"
     CDS             415..1086
                     /locus_tag="TU257_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834913.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1103..3376
                     /locus_tag="TU257_001938"
     CDS             1103..3376
                     /locus_tag="TU257_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834914.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3851..>4591
                     /locus_tag="TU257_001939"
     CDS             3851..>4591
                     /locus_tag="TU257_001939"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0834915.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAE"
BASE COUNT         1497 a          891 c          946 g         1257 t
ORIGIN      
        1 tggaagaggc ttttataaaa aatacatgaa tgcctatggg caggtggcaa ggctgcattc
       61 tcagcaatgg tacaccgatg tcgttcatct tcctgttgaa tttcctatgt cagccgatgg
      121 gcataggcca gtctctgaga ggtaccggac actatcagac aaagaaatca gagaaggctt
      181 tctctccatt ggaaaaacac cggagcttgt cagtggcagt caggtcgaga gattgcgaaa
      241 aatcattaac ctatatgacc tgccggttgt cgttccaatt gacgaggcag tcactcaagc
      301 agaggagcaa atcagaacca acagagaagc tgtctccaag cggattattg agcagtataa
      361 agagccttca ttaaaagaaa aaataaaatt tatatcagaa ttttaggagt gtagatgatt
      421 tcatttaaga atattagcaa gacataccaa gtcggagacc aagaggttaa agtattagac
      481 gatgtttcct ttacgattga aaagggaagg tttactgtta ttttaggccc ctctggttca
      541 ggaaagagca cgctcttaaa tttacttgga ggaatggacc gggcaagcaa gggaaccttt
      601 atctttgagg gtaaggacat tacagcctta aatgataaag cattatctga ttatcgcaaa
      661 gaggttgtag gctttgtctt tcagttttac aatcttattc caagcctaac agccttagaa
      721 aatatcagta tcgccgcaca gctaaccgga aacacagcac aatcagaggt attgttggat
      781 aaggtggggt tatctcatcg gaaaaacaat ttccctagcc agctgtcagg cggagaaatg
      841 cagcgcgtat ccatagccag agctctggca aagaagccaa aattattgct atgtgatgag
      901 cctaccggtg cccttgattc caaaacaggg cagcacatta tgcagctact tcaggaagcg
      961 tcaaaggacg aggacgtagc ggttgtcttg gtgacacata acactgaatt taaagctttt
     1021 ggcgatacca ttatttacct aaaggacgga aagataagct cgattgatca taaacaatca
     1081 gtttagagga ttggagctaa acatgaaata tcttaattta aagctaaggc gagatttaaa
     1141 gcatcattgg cagcaattct tttcagtgtt cttgatgtcc ttattaagtg ttttaatctt
     1201 tgttggtcta cagggtgctt ggcatgggct ggaaaaaagc ttagacaact atatatctac
     1261 ctctcatttg ccaaccgttt gggtacaggc tactaatcta acaaaacagg acattgaaaa
     1321 aatagaggcc ttaaatcaag tcagcaaggt tagacctaag attagggtca ctgctgctat
     1381 tgattctgac agcgacctag agcattactt aacgctagat tcattacagt ctacctcaga
     1441 tcaggtgaca cgtgttgtag ctggcgaggc cttttcaacc aaagaaaccg ataaagtatg
     1501 gttgaacaag gaatatgctg acgctaacca cctatccctc ggtgataaga tcagcttaac
     1561 actatcaggt caatcaatta gtgtgactct tgcgggtctt gtccagtcag cagacaggat
     1621 ctactttaca ggcagcttag agtatatagc tcctaattat gataactatg cctacggcta
     1681 catctcaaaa aagagcttag ctaagctcct tcagacgcag ctgcctgata atatggttga
     1741 catttacgcc tcgtctgacg atcttcgaga cgacatagag aacattttag gcaataagct
     1801 tgtttcttat tacaatcaaa caaccctaac tgacgtctct gaggcagttg atagagtagg
     1861 acagattagg aatctctctt atttgttctc ctttatcttc atcttactag ctattctatc
     1921 catgtttacc acgatcagac gtctcatcga aagtcaaaca aaggaaattg ctatcatcaa
     1981 ggccttaggc tattctaaca tacaggtcag tggccactac atttcctttg gcttgttggt
     2041 tggaacatta ggtgctcttt ctggtcttct ggtatctcct gctatgtcct ggtttgtcct
     2101 agagacccaa aagagaatgt tctcacttcc taagtgggaa attgcttact ctctgtcttc
     2161 cctagtagtt gcattactgg tggttatgat ttgtgtgaca tctgcttact ttgcttctcg
     2221 aaaagccatt aaagggctgc cagcagtatt cttacgagga aaaaacaggg acgtcaagca
     2281 tattttgctc gaaaaaatca agcccttatg gcgtagtatt tctgacgaag ctaagtgggc
     2341 tatacgtgat gctttgacac accgcatcag aattttaatg gggattatag gggtagctgg
     2401 tagtatgatg cttttaattg ccggtattgg catgcctatc tctatgaatc accttgttga
     2461 taaggcctat aacaaggact ttagctactc caaacgcttg acggtttctg actacgaatc
     2521 ggccaataag gcctataaag gccaatgggt gcaaatcaat caagcccact tctcaaaaga
     2581 tgacggctac aatcgtctct tgattattat cagcaaggga agccttgtta acgccaccac
     2641 agaagatggt gacaagataa aagagggtgg tctctatgtt accaacagct ttgccaagct
     2701 agccaatatc aaggttggag acaagctatc tgtcacaccc taccaggata agcatcagta
     2761 tacctttagt gttaagggaa ttctgaccag cgaaactaat caaggtgcct atatcatggc
     2821 tgataccttc aaaaaagcag gcggagcttt tcacccacac acattgttag tagataagca
     2881 agtttctgct tctacaatcg ctcaggatca gaatgtttta accgtcattg ataagtccag
     2941 ccaagaaagc aatgcctatg accttgtcaa tagtctaatg agtgtctttt tgatgatcat
     3001 tggctttgcc ttgctgctag tcatcgttgt gctgtataat ttaggctctt taaattttgt
     3061 agagcgcaca agagactacg caacccttca ggttctagga ttttcaaaaa gaaatctcca
     3121 aaacataaca atgctcgaaa atctcatgac aacctctgtg ggctggctct tgggaattcc
     3181 tatggggatt tggtttttag agcagtatgt cgccaccttc tctacgatac gtcttgaata
     3241 tacggcttat gtcacttggc aggttctgct agcggcaagt gtccttgtct ggctaacatc
     3301 attaatgacc actcttttca tcagtagaaa gattagaaca attgacatgg ttgatgcctt
     3361 aaagggagtc gactaacctc actttatcac atacctgact ctctctcttt tatggttaag
     3421 catcatcact gcactggttc tgatatgatg actgataaag ctgtaattgt gctgtaacaa
     3481 gcactgtcat tacatagcaa cacccttaaa aacaagcatc agatttggtg cttgtttttg
     3541 aatttattgc taatgctaaa cgcaacgatt atcacaaatc atgcagtaca cgcttataac
     3601 agcttaagca tgcccattat tcaaaaaacg ttgatcaaaa tgacttccct gaagtttaga
     3661 tcattcctca atttattgat acaaatgtga taaagtcata cgatcttctt gtttattaaa
     3721 aaaaaaaaaa aacgaaacta cggagagaaa gatgagcttt gtcgtttctc acttccaacc
     3781 gccatgttaa aatcttctct gagaaagaat gttataaaaa ataatcattc tatcaccaaa
     3841 ggagagaaaa atgataacta aaaaacagag aaaactaaaa agacacacaa caatcagacg
     3901 cctgtgtcat caagccctag cagctaccct catcacagga agcctgatgg gaacaggact
     3961 acttggaaat aaagtcgtgt atggggatat gaaaagcgat gccaaaaagg tattagcaac
     4021 attgcaaaaa ggtaatcata aacaagagtt aaaaaaagtt cttagaacta ttggtgatga
     4081 tagtttgcta ttattatggt tacttgtatc gggtgattcc aatttagatg aaagtaataa
     4141 aagttttgat tatttatcaa tttggaatac tggatctaga gttggtaaag tgatatctcc
     4201 tactgaatac tttaaacaag aatcaaaaaa cactgaaaat aggcaagctg tttatagtga
     4261 atttaaacaa cgcgtagaag aacgatctaa aaaagccaag gaagccactg aagcactaaa
     4321 ccaaaaagct caattggagg ctacagttaa aaatataaac gaagaacttg aaaaaactag
     4381 agaaggtttt aaagttgtga gtgaaaactc aaacaaatta gaaaaacaat taatggctga
     4441 gaaaataaaa acacgtacag ctgaagaaac tgccaaacaa gctaaaaccg ataaagaaaa
     4501 agcagaggct gaagctaaaa aagcgaaaga ggaagctaag actgcggaag gaaaagttaa
     4561 acaagcagaa actgagaaaa ggaatgcgga a
//
LOCUS       DARYJX010000073         4333 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYJX010000073 DARYJX010000000
VERSION     DARYJX010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4333
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(44..754)
                     /locus_tag="TU257_001940"
     CDS             complement(44..754)
                     /locus_tag="TU257_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0834916.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..2559)
                     /locus_tag="TU257_001941"
     CDS             complement(1201..2559)
                     /locus_tag="TU257_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL0834917.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(2967..3197)
                     /locus_tag="TU257_001942"
     CDS             complement(2967..3197)
                     /locus_tag="TU257_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834918.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(3291..3704)
                     /locus_tag="TU257_001943"
     CDS             complement(3291..3704)
                     /locus_tag="TU257_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834919.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(3739..3936)
                     /locus_tag="TU257_001944"
     CDS             complement(3739..3936)
                     /locus_tag="TU257_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0834920.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
     gene            complement(4218..>4333)
                     /locus_tag="TU257_001945"
     CDS             complement(4218..>4333)
                     /locus_tag="TU257_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL0834921.1"
                     /translation="KTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
BASE COUNT         1353 a          840 c          580 g         1560 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gcaaatcgaa tctttacatc ttctataaaa
     1861 taaccgcatt gtaaaatata aaatcaatat ttttccaact cctaaaatag ggaagtacaa
     1921 gagaaagtat ctgctatagg atatatttat ggagtaaaga cttaaaattg ctccagtaaa
     1981 aacattattt ggaacattgg aaggtaatac ataaaatgca ggtatatagg ttgctaaaac
     2041 ccctgacata acaattcctt cccattcctt acttcctttt tcataaccta attctaaaga
     2101 tagggcattt agaataggta aaagcaaaac tactctaccc attgctgatg gcatcaaaaa
     2161 aattagtacc actcctagca aaatcgtccc aaataacact ttagaatatt tccccatgca
     2221 caccggaata aaaaatctcg caagtaatct atcaagttca gtatgcttta ctgccgcccc
     2281 tataataaca cctgaaataa caagccatgc tgcacctgaa gttatccctg ataagatgac
     2341 ttgcttctca gctatattcc ctatcataca agctgtcata aataaaatgc ttgtatacca
     2401 tgcaggaatt atattgcttg ccaaaaggaa gatagatata agaatcaaaa taaaaacttt
     2461 ctctatattt gaaataaatg gtagtacaga tacaaacaac ggtaacattg taaatatcca
     2521 ctttatatga ttattcctaa ttccagattt taaaatcatc ctccattttt gacctccaac
     2581 tctaatttat ttcatagtat tataccatat ttattttcat tttataggtc tacctcttgc
     2641 ttctttgtct gtgttaatcg cttttcttgt ttttataact gctctataca agtcttaact
     2701 ttttctgcct gtttaatttt ttctcgtatc tctaatattt tattgtgtaa gctctttttt
     2761 tctttcttca tattggcgac ttccgatttt catttgctaa tgactaaggt cttgctttcg
     2821 cccaaatgct cttttagata tttcttggca ctctcaaata aaataatctc tgctgtatca
     2881 acgttagctg atatgccctc tgcaagagcc ttcggagaac gcacgcacct gttgaggtgt
     2941 atatgtacac tcttgtaaac aagggactat tcctctgtgt ccgttgcttc ctcttgcact
     3001 tctatgtttt cttctgtttg ttctcttttc tctatgattt ttaggatttt ttgattgact
     3061 gctccctttt cataaaggcg tctatctctc ttttttctct cttcctgttt cgactgaatg
     3121 atgggctttt ttcttttgtt ttgtaactgc ttgatttctc catctgtcat taaaattttt
     3181 tcatctatgt ttttcatttt ctattttcct ctctttctgt tttgagcaac aaaaaaacag
     3241 taaaccattt ttttgattta ctgttttcta ataaatatta tcttagttat ctattctact
     3301 tttcgtaaat ataaatgata aatccatgat acgataccac ttatcaaaac aactccaatt
     3361 atagaaaacc cagaaacttt gtttaaatag cccataaaaa ctagaagaaa aaaaactatt
     3421 cccagtaaag ttgtttgaat cacatatcct accatattag ccttagctgt tattaaggac
     3481 tctctttcat cggtttcatt tatccaatct tgttttttac ctgaaattga aaatacccat
     3541 attccactaa cacacagaag aatagcaaca acgagaaagc ctacccatgc aatatccatt
     3601 cttggaaata cctgtaaaat atctttttta aaaaataata tgcaagcaat caaggcaaaa
     3661 agtattccag tagcaataac tataatagct aactttcttg ccataaccat ctcttttttt
     3721 atatttcttt tcattttttt attcctcctc gtatataaag atatcttcaa tgcttaaact
     3781 aaaatactta gcaattttaa aagctaaaat aatggaagga ttataccttc cgttttctaa
     3841 agaaccaatt gtctgccttg atacttcaag aatagatgct aactcttcct gtgttattcc
     3901 attttctttt ctgatttcct caagtctatt tttcacattt aatgacctcc tgcaacaatg
     3961 acaagctaac tttacatata gtataatgtt ttttagagaa aatggcaagt atactttcca
     4021 taaaatcgtt tccttatagg tctagccctt acttttttac atgtacgact cctctatatc
     4081 tgcattttcc tcttatactt ctgtctgttg atgagcactt gcttctcttt gtgatgatat
     4141 ctttactatg cttttcattt ttgggatttt tatcttaatt ttgagtagtc ataactaatg
     4201 cccgtaaaaa cgggctttta tcttgtttta aaactgccat ctgaaaatgg atcttcatat
     4261 tctttaacac tcaacttatc aagtgcaatg tcatttttct cctgctcgcg aatatatttc
     4321 gctaccgtct ttt
//
LOCUS       DARYJX010000074         4316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYJX010000074 DARYJX010000000
VERSION     DARYJX010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            104..286
                     /locus_tag="TU257_001946"
     CDS             104..286
                     /locus_tag="TU257_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0834922.1"
                     /translation="MLIYDEFKQAVDNGYITGDTVAIVRKNGQIFDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            484..873
                     /locus_tag="TU257_001947"
     CDS             484..873
                     /locus_tag="TU257_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL0834923.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            870..2081
                     /locus_tag="TU257_001948"
     CDS             870..2081
                     /locus_tag="TU257_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0834924.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2094..3440
                     /gene="asnS"
                     /locus_tag="TU257_001949"
     CDS             2094..3440
                     /gene="asnS"
                     /locus_tag="TU257_001949"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL0834925.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            3740..>4316
                     /locus_tag="TU257_001950"
     CDS             3740..>4316
                     /locus_tag="TU257_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0834926.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEAGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPK"
BASE COUNT         1261 a          900 c         1078 g         1077 t
ORIGIN      
        1 tcacacacat gtattcacac attggcatat ccgttataac ggacttgtta aaattagtcc
       61 attaaactag actttttacg aataataagg taggaggtaa tttatgctaa tatacgacga
      121 gtttaagcag gcagttgata acggatatat cacaggagac acagtagcga ttgtgcgcaa
      181 aaacggacag atttttgatt atgtgttgcc gcatgaggaa gtaaggaacg gggaggttgt
      241 gacagacgaa aaagtggaag aggtgatgag agaattagac aaataaaaaa gacctcgtcc
      301 agaagtcggg gaattgtcgg ggacaacgtt tgtaaatgtt tctattccaa cataaaacat
      361 tttttgatat aataggaagg atcatatgca aaggagctga aattggacaa gcacaaaagg
      421 ctcaaaacag ttttatatca atgtgccagc ttggtcgtac tgctttgtct tggagtgatg
      481 agcatgtttt atcttgctgt tcatgatcaa tttgacaaga aatcaaggtt agccgagata
      541 gcaaaatcaa gagctggtgt catctcaatt gatcatattg attgctatca tggcactcag
      601 agctacctca gtctttttgg aaaaaacaag gcaggcaata ccatcatcgt cacaatagag
      661 gagcaatcag agcagctctt gcttagtcgc cctagcaatg gcattagtgc taaggaagca
      721 caggaaattg cctaccatgc cggagcaagg actattgaag cagtgacatt tgggattgaa
      781 aaccacaaga ggatttggga ggtggctgct caaaacggct actatctgat tgatttcaaa
      841 accgcaaaag tgatcaaaaa ggaggtttta tgaccaagct atcaaggcgc gtgttagcaa
      901 tggaagaaag cgtcacccta gcagcaggtg ctagagcaaa ggcactaaag gctcagggac
      961 gcgatatttt aagcctaact ctgggagagc cagattttat aacaccgcag catatccaag
     1021 aaaaggccat tgaggccatc accactggta aggcaagctt ttacactgtt gcttcggggt
     1081 tgccagagct caaggacgcc attgctgatt acatggcacg atcctatggt tatattccta
     1141 ccagacagga gattgtagtg gggacaggcg ccaaatacgt tttgtatgcc tttttcatgg
     1201 ctgttttaaa tcctggtgat caggtgttga ttccgactcc ttattgggtt tcttatgctg
     1261 atcagattaa aatggtagac ggggtaccgg tctttgtaca gggcttggag gaaaatcaat
     1321 ttaaggtcac agtagagcag ctagaggctg ccagaactga tcaaacaaag gttgttttga
     1381 tcaattctcc gtccaatcca actggcatga tttacagccg acaggagctt gaagccattg
     1441 gcaattgggc tgttcagcat gatattctga tcctggcaga tgatatctat ggtgcattgg
     1501 tctacaatgg caatcaattt actccaatat cagccttatc agaggctatt cgtagacaga
     1561 ccattactgt aaatggcgtt gccaagagct atgcgatgac aggctggcgt ttgggctttg
     1621 cggtcggaga cactgatatt atcgctgcta tgggtaagat tatcgggcaa accacctcta
     1681 atgtgacaac agcgtcccaa tatgcagcga ttgaggcctt tggcggtgac caaacgtcag
     1741 ttgaggagat gagacaggcc tttgaagagc gcctcaatac catttatccc ctgctcaatc
     1801 aagttcctgg ctttgaggct attaagcccc aaggagcctt ttatttcttt cccaatgtca
     1861 aaaaagctat ggagatgaag ggctttaccg atgtgacagc ctttactgat gcgatcctag
     1921 aagaggtagg actggctgtt gtcagcggag ctggctttgg tgctccagaa aatatcaggc
     1981 taagctatgc cactgatttg gcaaccctaa aagaagctat cagacgactc aatcagttca
     2041 tgacaactga cagcagccat gacaacaaag agaatgaata gaaaagagac attatgacca
     2101 aaaaatacgt ttccattatc gatgttaaag accatgtagg acaagaagtg acagttggtg
     2161 cttgggtcgc caacaagtca ggcaaaggga aaatagcctt tttgcaattg cgtgatggct
     2221 cagccttttt ccaggcagtt gcctttaagc caaacctgat ccaagccttt ggtgaggaag
     2281 caggagcagc taagtttgac acgattaggc atctcagcca agaaacctct gtcttagtaa
     2341 agggcattgt caaagaggac gctagatcaa aatttggcta tgagctagac attacggacc
     2401 tagaggttat tggggattcc aaggattatc caattactcc aaaggagcat gggacagact
     2461 ttctcatgga tcaccgtcac ctttggctgc gctctcgcag gcaggcagca atcatgcaaa
     2521 tccgtaatgc catcatctat gcttcctatg agttttttga tcaaaatggc tttatcaagt
     2581 ttgatagccc gattttatca ggcaatgctg ctgagaacac aacagagcta tttgagacag
     2641 attattttgg caatccagcc tttctcagcc aatcaggtca gctatacctt gaagctggta
     2701 tgatggcgct tggtcgcgtc tttgactttg gtccggtatt tcgtgccgaa aaatcaaaaa
     2761 cgcgccgcca tctgacagag ttttggatga tggacgcaga ataccccttc ttatcccatg
     2821 aggaatcctt agacctacag gaagcctatg ttaaggcgat gattcagggt gtgcttgatc
     2881 gtgctccaca ggcattggag cttctagagc gtgacacaga gctgctgaaa agatacattg
     2941 cagagccctt caagcgtgtc tcctacgacg atgcgatcag cctgcttcag gagcacagca
     3001 cagatgacga tgccgactat gagccaattc agcatggcga tgactttggc tcaccgcatg
     3061 aaacctggat ttccaattat tttggggtcc caacctttgt catcaactac ccagctagct
     3121 ttaaggcctt ttacatgaag ccggttcccg gcaatgaaga gcgcgtgcta tgtgcggacc
     3181 tgctagcacc agagggctac ggtgagatta tcggaggctc ggttcgtgag gataactatg
     3241 acaaattgtt ggcgaaaatc aaggctgaag gcctaaatcc tgaggattat gacttttacc
     3301 ttgaccttcg caaatatggc tcagtgccgc atgctggttt tggacttgga ctagagcgca
     3361 tggtgacctt tgttgcaggt accaagcaca ttcgtgaggc tattccattt ccacgcatgc
     3421 ttcatcgctt aaaaccataa tgaaccctat cagcgtccgc cattgggcgc ttttttgctg
     3481 cgctgagcag tacttagagc tcaagcctcc cagttagact tggcagagct gtggctcttt
     3541 gcttgagcta ttgtaggcaa aggtatcact ggatctgaaa acaacaaaat cagacaagtg
     3601 atatcaaaat taaaaaaaaa aaaaacgaaa cctaggagga tcggtgagct tattagtttg
     3661 gcactaatca tcattatgct ataattgtct tcacaaataa tttagaaata gctcatattt
     3721 ctatcattaa aggagagaga tgatgaatcg taaaaagcat accaaactca ttcgtcacta
     3781 cagtatctgc tcagcagtgg ctgtcctagc agcagttagc ttgggaacag gtcaggacgt
     3841 acaggcttcg gaacccaatc catatccaga tgtgaggcgt ttccttgatg agaagtacga
     3901 tggagatgtg gataaattat ctaaacaact tcaaggttat tttggtagtt taagagagta
     3961 tatagagttt gaacttaaaa atggcaaaca aggtcctgct ggccctcaag gcccaaaggg
     4021 tgataaagga gaccccggag agccaggtcc tcaaggtcca gtgggccccg ctggtccaaa
     4081 gggtgatcgt ggtttagacg gacgacgtgg cccagcaggt cagcaagggg aagccggccc
     4141 agttggtcct cagggtcctc aaggcgagca agggccaaaa ggcgaccgtg gcgaacaagg
     4201 accaaagggt gaacgcggtg agcaaggacc aaagggtgaa cgcggtgagc aagggccaaa
     4261 aggcgaccgt ggcgaacaag gaccaaaggg tgaacgcggt gagcaaggac caaagg
//
LOCUS       DARYJX010000075         4071 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYJX010000075 DARYJX010000000
VERSION     DARYJX010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4071
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            295..2097
                     /locus_tag="TU257_001951"
     CDS             295..2097
                     /locus_tag="TU257_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0834927.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TU257_001952"
     CDS             2075..2674
                     /locus_tag="TU257_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0834928.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TU257_001953"
     CDS             2782..3708
                     /locus_tag="TU257_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL0834929.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4071
                     /locus_tag="TU257_001954"
     CDS             3701..>4071
                     /locus_tag="TU257_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0834930.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGLP"
BASE COUNT         1256 a          756 c          786 g         1273 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggacttc c
//
LOCUS       DARYJX010000076         3995 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYJX010000076 DARYJX010000000
VERSION     DARYJX010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3995
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU257_001955"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU257_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL0834931.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1290)
                     /locus_tag="TU257_001956"
     CDS             complement(664..1290)
                     /locus_tag="TU257_001956"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL0834932.1"
                     /translation="MSITAILLLSPNKDLMCDACQRHFCRITQPTCSNCYQYRHEGAC
                     QDCIAWKRQGYQVDHQSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKA
                     YTLVPVPVSKQRYDERGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNR
                     YRLKKGAALPPKILLIDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TU257_001957"
     CDS             complement(1473..1658)
                     /locus_tag="TU257_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0834933.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU257_001958"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU257_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL0834934.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..3626)
                     /gene="spek"
                     /locus_tag="TU257_001959"
     CDS             complement(2835..3626)
                     /gene="spek"
                     /locus_tag="TU257_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL0834935.1"
                     /translation="MRRKNEKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNI
                     YAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKK
                     VISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYIDGGIIKTSDVKPEEKAIY
                     INIFGEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFW
                     DIHYKDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVYLNEEFSKN"
     gene            complement(3738..>3995)
                     /locus_tag="TU257_001960"
     CDS             complement(3738..>3995)
                     /locus_tag="TU257_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL0834936.1"
                     /translation="SKSGTFTLDAAEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYAN
                     GYYWISYVGGSGKRNYMAIGPTDKDGNIISLWGKLGGKDPR"
BASE COUNT         1200 a          806 c          586 g         1403 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatat taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatcttat ctttagctgt taatgttcgt
     3121 aattcttttt caccaaaaat attaatataa attgcttttt cttctggttt tacatcactt
     3181 gtttttatta ttcccccatc aatataattg aattgttcct tgcatacaac atgatatgac
     3241 tttactatag caaaaatatt cacatgatca ccaacattaa acattctttc ctgtgaagga
     3301 gaaagattac tagatatgac tttcttaaaa gtgttatcat tccaaactgt agtattttca
     3361 tccgtattaa aaatcaattg cgttccttgt ttggcattta tcgatatatt atttttttca
     3421 ataatttctt tattatatat ttcttttaat cttctattat ctaaaatttc gtctttatca
     3481 tatctaggag catatatgtt ccttggattt ctaacatcat ttgtattgta cgtatctgaa
     3541 aagacactct cagtagtgca tagggtaagc gatacacaca caaggaatag caaagccaag
     3601 gtattttttt cattttttct cctaatattt tttaaattta atcaatttac ttagcaagta
     3661 tactatattt aaataataat tcaactataa tttaaaaaaa acaaaaaacc gccctcaatc
     3721 aagagagcgg ttttgtctta tctcggatct ttacctccta atttacccca aagactgata
     3781 atattcccgt ctttgtcagt aggaccaatt gccatataat tacgcttacc tgagcctccg
     3841 acatagctaa tccagtagta gccattggcg taaccctcac tatcaaagct aacggtttgg
     3901 ccttgcttat aactatctac tacctcactg gttaaattcg gccagcggcg gacgttgatc
     3961 tctgcggcgt caagtgtaaa agtacctgat tttga
//
LOCUS       DARYJX010000077         3705 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYJX010000077 DARYJX010000000
VERSION     DARYJX010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3705
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            11..81
                     /locus_tag="TU257_001961"
     tRNA            11..81
                     /locus_tag="TU257_001961"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Gly,seq:tcc)
     gene            111..184
                     /locus_tag="TU257_001962"
     tRNA            111..184
                     /locus_tag="TU257_001962"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:145..147,aa:Ile,seq:gat)
     gene            197..268
                     /locus_tag="TU257_001963"
     tRNA            197..268
                     /locus_tag="TU257_001963"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:230..232,aa:Glu,seq:ttc)
     gene            279..368
                     /locus_tag="TU257_001964"
     tRNA            279..368
                     /locus_tag="TU257_001964"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:315..317,aa:Ser,seq:tga)
     gene            380..453
                     /locus_tag="TU257_001965"
     tRNA            380..453
                     /locus_tag="TU257_001965"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:414..416,aa:Met,seq:cat)
     gene            478..550
                     /locus_tag="TU257_001966"
     tRNA            478..550
                     /locus_tag="TU257_001966"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:511..513,aa:Phe,seq:gaa)
     gene            570..650
                     /locus_tag="TU257_001967"
     tRNA            570..650
                     /locus_tag="TU257_001967"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:604..606,aa:Tyr,seq:gta)
     gene            657..727
                     /locus_tag="TU257_001968"
     tRNA            657..727
                     /locus_tag="TU257_001968"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:689..691,aa:Trp,seq:cca)
     gene            739..811
                     /locus_tag="TU257_001969"
     tRNA            739..811
                     /locus_tag="TU257_001969"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:772..774,aa:His,seq:gtg)
     gene            820..891
                     /locus_tag="TU257_001970"
     tRNA            820..891
                     /locus_tag="TU257_001970"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:852..854,aa:Gln,seq:ttg)
     gene            910..993
                     /locus_tag="TU257_001971"
     tRNA            910..993
                     /locus_tag="TU257_001971"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:944..946,aa:Leu,seq:caa)
     gene            complement(1337..2467)
                     /locus_tag="TU257_001972"
     CDS             complement(1337..2467)
                     /locus_tag="TU257_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0834937.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            3032..>3705
                     /locus_tag="TU257_001973"
     CDS             3032..>3705
                     /locus_tag="TU257_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0834938.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQR"
BASE COUNT         1136 a          717 c          861 g          991 t
ORIGIN      
        1 tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct gttgtcgcga
       61 gttcgattct cgtcacccgc tttatagttt tcccaagcta tagtgtgctt gggcgcgtag
      121 ctcaggtggt tagagcgcac gcctgataag cgtgaggtcg gtggttcgag tccactcgtg
      181 cccattaaga tatgatggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
      241 aacacgggtt cgaatcccgt acggactata ttgtcattgg aggattaccc aagtccggct
      301 gaagggaacg gtcttgaaaa ccgtcaggcg tgtaacagcg tgcgtgggtt cgaatcccac
      361 atcctccttt aaagattatc gcgggatgga gcagttaggt agctcgtcgg gctcataacc
      421 cgaaggtcgt aggttcaaat cctgctcccg caattatata aaagatatat gctggttggc
      481 tcggtagctc agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg
      541 tctcgcgcca tagtaattta atatgttttg gaaagatagc gaagaggcta aacgcggcgg
      601 actgtaaatc cgctccttcg ggttcggggg ttcgaatccc tctctttcca tcctgaacgg
      661 gcatagttta aaggtagaac taaggtctcc aaaaccttca gtgtgggttc gattcctact
      721 gcccgtgttc agaatatggc gggtgtggtg aagtggttaa cacatcagat tgtggctctg
      781 acattcgtgg gttcgattcc catcactcgc ctattttatt ggggtatagc caagcggtaa
      841 ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca gtttagtttt
      901 atacttaaag ccggcgtggc ggaattggca gacgcgctgg actcaaaatc cagtgtccgc
      961 aaggacgtgc cggttcgacc ccggccgccg gtatagttta aaaatattga aaaaacaagg
     1021 tttgtaaacc ttgttttttt gttttatgac ttgatgtcag aggatcagat tggtcctctc
     1081 tagatgttaa aggtaatgag aatcttggct tcaaagctcc taaatccaaa gcattgcgct
     1141 tgatgtcttt gatcacctgt tagtggcgtg cagcttagcg tttgaatttg gaataaggtt
     1201 gctccaaggc atgtgtgatg tgagctttgg atactaggac ttttagccaa ttctttgtgg
     1261 gtgagctttt tctttacgtt tggttttgat taatgtcgca atatcagtta tcatgtgttc
     1321 tctggttaat gacgctttag caaatatcgt attgtcttag catcttgttt gagaaataaa
     1381 gcagactaat taagataagc gaacccaagg caagtgttgg gatggttacg gtataaaaag
     1441 cactgaaaac ttcaccaaga tgctcatcag gaatctcagt tcgtaaaata ggtttttggg
     1501 taacatgcgt tattccgaga aatagacagg aaagaaacca aagaagcaac aaaccaaaac
     1561 ggttggggac taatgctgta aggccaatac cggtgcccaa aagggtagtt gctagccaaa
     1621 aagcttttcc tacacttaac ttttgcaaga caaggttagc aacaaaggtt gttcctacca
     1681 gggttccgat agcacttaca gatactaaga ggccataaaa agctgaattc cctacctctc
     1741 ttgctattaa taactgatag acatttaagc tggcaaaaag gaaattagcg atagcacctc
     1801 ccaatgtgat ggctaacacc actttattgt gccagataaa gcgcaagcca cttaaaaagt
     1861 ctgttcgttc atttgtttgt tcaattattt ctttaaatgc tattcttcta aaaaatagga
     1921 ttgaacctaa gaaggtaacg atattaatga aaagcaaagg aatgtagctg atcacagaaa
     1981 gcaaaaagcc actgatggca gtaaaaacat aatctgttcc attataagcc actgacatat
     2041 acatttctgc tttagctaga tctttagtag gaatgagttt aggtacaaga gcatcttgaa
     2101 cagtataggt attcaaccca accatagaag ccagaaaaac acaactaaaa ataatggtta
     2161 agctaagact tgcgtgtatc tctcttaagg acattcctaa aataatacct aagacagcca
     2221 ataattgggc ccactccaga atcactagca ggttcttctt agggtacgaa tcaatctttt
     2281 ttccaaagat aaaggagaag gtgtttggaa taaaaatgag aaagttcaat aatccaacat
     2341 accaagtact attagtggtt tctagtacat accaggacag cactagggta taaatcgagt
     2401 caccgcaatt gctaatcagt cgccccagaa ataaccggca aaaatcatta tatttcctta
     2461 atatcatatt gtatcctttg ataaagagtt taaacatctt ttatattata gtatcagatg
     2521 ataaaaaatc actgaatgat agctgtgttt gatgtttgca acattttaaa atatctttgc
     2581 aaaaatcata cctagacaca tacaatccca cataagtttt aaaagcattc aattgccttt
     2641 taagatcttt atgagtcatg tttgtaaaga tatcctcttg caacagatct cttaatctct
     2701 aattgtatcc aataagaagc agctttgtca atacggaagc cgaatagtct ttttgccttt
     2761 ccttgtcagc tgggcaatca tgagggcttt gtgctttgat cttttgcatc tataaaaggg
     2821 tgaatctatt gatgaggtgt tatcggtagt ggggcctact gatgtcaata actgacgtca
     2881 gataattacc tctttaatta gaaaaaaaaa aaaacgaaac tacggagaga acctaataac
     2941 tggctatttc ttgctataag ccagcgtgtt aaaatcttct ttgggagaaa atttagaaaa
     3001 aaataatatt tctatcacta aggagagaaa gatgacaact aaagaaaaac aaacaaaact
     3061 aatgcgcagg tatggcattt tctcggtagt cgttgcccta acagctctag caggtctagg
     3121 agcagctaat gaagttaagg caactgctaa aaaatcttta aatgagttac ctaatccagt
     3181 agaaattatt caatataatt caacaagaac tactgataga gaagctagaa agtatcttaa
     3241 tcaattatat gagtttttga aaccttattt aggaagttta gaagaagaag ctcaaaaagg
     3301 agggccacaa ggacctgtgg gacctgctgg tcctagaggt gaacgcggag aaccaggacc
     3361 taaaggagac cgaggtcctg agggccaaag aggtgagcaa ggcccagcgg ggcctattgg
     3421 accccaaggg cctcgtggtg acaagggtga aactggagaa attggaccta ggggagaaca
     3481 aggtccgacc ggtcctactg gtaagccagg agagcgtggc cctaagggtg acagaggcga
     3541 acgcggcgaa aaaggcgagc aaggccagcg tggcgaaaaa ggcgagcaag gccaacgtgg
     3601 cgaaaaaggt gaacaaggcc aacgcggtga aaagggcgag caaggccaac gtggcgaaaa
     3661 aggtgaacaa ggccaacgcg gtgaaaaggg cgagcaaggc caacg
//
LOCUS       DARYJX010000078         3631 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYJX010000078 DARYJX010000000
VERSION     DARYJX010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3631
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..330
                     /locus_tag="TU257_001974"
     CDS             <1..330
                     /locus_tag="TU257_001974"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834939.1"
                     /translation="NRDERLKLYSEIVQKEISKEISYEDILKLFNIHNKTLNGFKTSI
                     SPYIGNVEVILNDKYMCDYGISDENVLKQWKDICFGIFTSHKVKKELIKEFLLKTTMT
                     EENNNEQ"
     gene            320..907
                     /locus_tag="TU257_001975"
     CDS             320..907
                     /locus_tag="TU257_001975"
                     /inference="COORDINATES: protein motif:HMM:TIGR02185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0834940.1"
                     /translation="MSNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLI
                     ALFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRA
                     ITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSP
                     AILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
     gene            909..1580
                     /locus_tag="TU257_001976"
     CDS             909..1580
                     /locus_tag="TU257_001976"
                     /inference="COORDINATES: protein motif:HMM:NF014420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0834941.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIF
                     ICVRY"
     gene            1594..2970
                     /locus_tag="TU257_001977"
     CDS             1594..2970
                     /locus_tag="TU257_001977"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834942.1"
                     /translation="MVELKNISYSYSKENQILQDINIKIQDGECILLCGRSGCGKTTI
                     GRIINNLIPRFFERGVMSGDVYINNENTKDFEMHELANLIGTVFQNPKAQFFHTNSDA
                     EIVFGLENNGMKPEKIRRRYKEVVDELNIHDLTNRDMFSISGGQKQIIAFASIYAMNP
                     KVYVLDEPTANIDKKTIIKIGKIIEKLKKRGHTVIICEHRLYFLKDLVDRVFYVDQGE
                     IKRTFSGDEFFRLENKERISMGLRTLEVPKLKNMLTYDEICDNTLKIKNLSCCYGEKI
                     VFKNLNLSIRSGEILGIIGNNGVGKTTLLRCIAGLHKETKGEITLNGDVISGKKRQRL
                     SAMVMQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLIESKKSHPMILSGGQKQ
                     RLVVANAILSDKKILIFDEPTSGLDYEGMLAVSNELKKLSEKNYYIFVVSHDIEFINE
                     ICDRVYEF"
     gene            2993..>3631
                     /locus_tag="TU257_001978"
     CDS             2993..>3631
                     /locus_tag="TU257_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834943.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNSTIVEYISGIEVIK"
BASE COUNT         1359 a          372 c          672 g         1228 t
ORIGIN      
        1 aacagagatg aaagattaaa attatactct gaaattgtgc aaaaagaaat aagcaaagaa
       61 ataagttatg aagatatttt aaaattattt aatatccaca ataaaacatt aaatggattt
      121 aaaaccagta tatctccata tattggaaat gtagaggtta ttttaaatga taaatatatg
      181 tgtgattacg gaatttctga tgaaaatgta ttaaaacaat ggaaagatat atgctttggc
      241 atttttacaa gtcataaagt aaaaaaagaa ttaattaaag aatttttatt aaaaactacg
      301 atgacagagg agaataataa tgagcaataa gttaaaagga aaagatttaa taacaatagg
      361 catttataca gcaatttatt ttgtaataaa ttttgcattt atgctagctg gaatgatacc
      421 agttatgtgg attatgatgc cttcactgat agctttattt acaggggtgc catacatgat
      481 gatttgcaac aaagttcaaa aagctggtgc tattttaatc atgggaacag ttacagtttt
      541 gatatattat gcaacaggac aatttacaac agttattctt gcaacttttg cagtaggttg
      601 tatattagct gaaattatta gagcaattac tagatataca agttttatag ggaatacttt
      661 atcatttgca ctattttcaa ttggaatgat aggatcgcct cttcctattt ggttgtttaa
      721 agaatcattt tttgctcata tatcagaggt tggtatgtcg caggattaca taaatgcctt
      781 ggaaaagttt acttcgccag cgattttgat aggagttatt attttgactt ttatttgttc
      841 gttagttggg gctttgattg cgaaaagaat gatgaataaa cattttaaaa aagcgggaat
      901 tatataaaat gcgtgaatat agattaaaaa tagatccgag agcagggatt tccctgcttt
      961 ttatcttaaa ctttacgata tttaatgtat ccacagttta tgcattattt gtgctattaa
     1021 tttggaactg tgtttatgca atgtgtaatg gatattgtag gatagcaatc aaattcattt
     1081 ttacttattg gttgctttat ttgatagaat ttttggtttt accgaaacta ccaagtttaa
     1141 ttgctatttc ctttgctatt ctattaactt atattttaaa gatgttacca gtagcattgt
     1201 ttggatatgt ttttgttaaa actacaagtt tgtatgagtt aattacggca cttagaaaaa
     1261 ttcattttcc agaaagtata ataacgggat tatcaataac tcttagatat tttccggcat
     1321 taagagaaga ttttcataaa acatatgatg ctatgaaact aaaaaatatg tctgttttag
     1381 aaaaaataag tggactgata attactacaa tgacaagagc cacattaaat atagaagaat
     1441 tatctcaggc agcaagtgta agaggcatag ataatcctgt aaaaaaattt tctgcggctg
     1501 aaataaattt taagacaagt gatgcggtag tgtttatagt gtcttctgtt gtctatattt
     1561 ttatatgtgt taggtattga ctggaggata gatatggttg aattaaaaaa tatttcatat
     1621 tcatattcaa aagaaaatca aatattacaa gatataaata tcaaaataca ggatggagaa
     1681 tgtattttgt tatgtggaag aagtgggtgt ggaaagacaa caataggtag gattataaat
     1741 aatttaattc ctcgtttttt tgaaagagga gttatgtcag gtgatgttta tataaataat
     1801 gaaaatacta aagattttga aatgcacgag ctagctaatt taattggaac cgtttttcaa
     1861 aatcctaagg cacagttttt tcatacaaat tcggatgcag aaattgtatt tggtttagaa
     1921 aataacggga tgaaaccgga aaaaataaga agaagatata aggaagttgt agatgaatta
     1981 aatatccatg acttgacaaa tagggatatg ttttcgattt cgggtggaca aaaacaaata
     2041 attgcatttg cttctattta tgcaatgaat cctaaggtgt atgttttaga tgaaccaaca
     2101 gcaaatattg ataaaaaaac aattataaaa ataggaaaaa tcatagaaaa gctaaagaaa
     2161 agaggacata cagtaattat atgtgaacat agactttatt ttttaaagga tttggttgat
     2221 agagtatttt atgttgatca aggagaaatt aaaagaactt tttcagggga tgagtttttt
     2281 agattagaaa ataaagaaag aatatctatg ggtcttagaa ctttagaggt accgaagtta
     2341 aaaaatatgc ttacttatga tgaaatatgt gataatacgt taaaaattaa gaatttgtct
     2401 tgttgttatg gagaaaaaat agtttttaaa aatttaaatc taagcataag atctggagaa
     2461 atattaggaa ttataggaaa taacggtgtt ggaaagacta cacttcttcg atgtattgca
     2521 ggattacata aagaaacaaa aggagaaatt acattaaatg gtgatgttat aagtggcaaa
     2581 aaaagacaaa ggctatctgc aatggttatg caagatgtga attatcagtt atttgcagat
     2641 agcttagtag aagaatgttg cttaggaaat aactgtgata atatacaaat tgataaggtt
     2701 ttgggtgaac taaaattaat tgagtcaaaa aaatcacatc ctatgatact ttccggtgga
     2761 caaaaacaaa ggttagtagt tgcaaatgcg attttatctg ataagaaaat attaattttt
     2821 gatgaaccga catcaggatt ggattatgaa ggtatgcttg cagtgtctaa tgaactaaag
     2881 aagttgagtg aaaaaaatta ctatattttt gtggtttcac acgatataga atttataaat
     2941 gaaatatgtg atagagttta tgaattttag ataaaggagg tggagaagtt acatgagcaa
     3001 caaaaactgg ataaatacta tattagattt tgcttcagat tgtaaaggaa agttgatttt
     3061 atcagtagtt atggctagta taggagtgtt ctttagcatt ataccttatt ggtcagtata
     3121 taaacttatg gcagtcttta tagaacaaaa agcaactgga gaagatgtat tgtattatgg
     3181 agcgattggt attattgcat attttatcag atatatttgc catggagtat caacaatatt
     3241 atctcatata tccgcttaca caatcttaag aaatataaga gaaaatttag gtgaaaaatt
     3301 gctcagtatt tctatgggaa atgcgtcaaa aaagacaata ggagaatata agtcaattat
     3361 tgtagacaaa gttgaaacaa ttgagatgcc tctagcacat atcataccag agtgtgttgc
     3421 tgcattgctt ttatcactag gtattgcaat atttatggtc ttcataagtt gggagatggc
     3481 tcttgcgatg tttattacag tgccttttgc tttgatggca tataaaaaac taatgggtaa
     3541 ttttaatcag ctttatgaag ctcaaatgaa atctaacaag tatatgaatt ctacaatagt
     3601 agaatatatt agtggtatag aagttataaa a
//
LOCUS       DARYJX010000079         3599 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYJX010000079 DARYJX010000000
VERSION     DARYJX010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3599
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1..1766
                     /locus_tag="TU257_001979"
                     /pseudo
     CDS             1..1766
                     /locus_tag="TU257_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            complement(1787..3400)
                     /locus_tag="TU257_001980"
                     /pseudo
     CDS             complement(1787..3400)
                     /locus_tag="TU257_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1267 a          690 c          479 g         1163 t
ORIGIN      
        1 tactttaact atgttaaagc aaaggctatt atagaaaata attcttacct atcctttaat
       61 aaactaaaag cagtaggaat tttagatcca attgattatc tacaaaggct taatggtaaa
      121 attggatatt acacaaaaaa ttactctcct ctaggagatt gtatgtatct aacacaagaa
      181 aatactgaaa aaattgataa tatcagacag atcatagaag attggaacaa caatcaatta
      241 ctcacagagt acgaatattt ttacctttta aatgctttga tagaagctat tccttatgtt
      301 agtaatatta ctggaaccta tggcgctttt ctcaagcatt gggacaaccg agcgttgcat
      361 tccttaacat tagcagaaga gactattttt gataattatc gtcctaacaa agcgtttaat
      421 gaaaatgcta atgaattagt caaaaaaata aaagcagata ttgtttacat tgataccccc
      481 tacaatgctc gacaatacgc atcaaattat catttactcg aaaacatcgc ccgacatcaa
      541 aagccaattt taaaagggat tactaaaatt tttgattgga aaactcttaa aagtgattat
      601 tcaacaaaaa caaaggcttt aaaagcaatg gaagatttaa ttgctaatat taatgctagt
      661 catatcattc taagttacaa taccgagggt attatatccg aagaagattt aacactttta
      721 cttcaacgat attcgttcaa taatcaaatt gatgtgaaac ggattcctta ccgaaaatat
      781 caatctaaga aaaaatctca gaacaaagac ttatacgaac ttctttttta tattcaaaga
      841 aagccgataa ataatcgctt caaatcacaa actaaaaaaa aggcagccat catcagtcaa
      901 aaaaagtata taaaaagccc attaaattat atcggtggaa aatatcgact gctaaatcaa
      961 atcattccaa tttttccccg acatatcaat acatttgttg atatgtttag tggggggcaa
     1021 acgttggtat caatgttcct gctaaaaaac acatctttaa tgatatgaac tatcgcatta
     1081 atgacatgtt tcgatatttt caatcacatg acccacttga gatacttgaa caaattgagc
     1141 atcgaatttc agaatatcaa ctcagcaaga ccaatgaaca aggcttttta acattccgaa
     1201 aacattataa tactcatcca aatccactag acttatacgt actatcgtct tatagctata
     1261 actatcaatt tcgctttaat aactcaatgg aattcaataa cccattcggc agaaatagaa
     1321 gtcattttag tgaaaatatg aaatccaatc tactcaattt tgtagctcga ctacaccgtt
     1381 tagatgccac tttctctgat caatttttct cagattttga tatttctaca ttatcaatag
     1441 atgattttgt ttatcttgat cccccctacc tcataacgac tggcagctat aatgatggaa
     1501 atcgtggctt cacaaactgg ggcgaaaaac aagaaattga aatgtatcaa ttaataagag
     1561 accttaacaa gaaacaaatt aaggttgcac ttagtaatgt tcttgttcat aaaggaaagc
     1621 acaatgattt acttgagcaa tttgttcaag atgaaagtct atatctcacc actttaaatt
     1681 acaattataa aaatgcttca tacaacacaa gaaaagaaga tagcattgaa gtattgatta
     1741 ccaattataa accaaatcca aaataataaa agcatagttg aattagctat gcttttacaa
     1801 attcaatttc tttattttga aaataagatg gtaaatcgga aatatgcagt tgtcctttaa
     1861 gaaccaaatc tgctcccaaa agcaattgct ctacattgag ggctgctccc ttaatttgtg
     1921 tttcattaga ggtataatca agctgctctt gaaattttcc aatgaattta cttgacaccc
     1981 acataaaata aaactcttct tgtggaatcg tatctggaaa agcttcccac cactttatcg
     2041 gattacgatt ttcatctcgt cgcttattat cctcaatata ccgaatcatt tcatcagcct
     2101 gattgataga tttagaataa ccttttccat aagcctttgt atctacaatc acaccaaaac
     2161 gatcttgata gagtaaacca tctggctttc tgccaccacc taaaagctta gaatgcaatc
     2221 tatatacatt tctaaataat tccattgtaa caatttcaaa atctcgattt cgcttaccat
     2281 cgtaagcaat atcaagcaat tcaatatatt tcattggtaa attagtctct tttaaaaatt
     2341 ttgccttacg cttttctgcc tgctcatcct ttaattcttg tgtaatttct agttcaggaa
     2401 tagaaaaatc gttgatctta tccttcaaag aaactctatt gctagaaata tctatcctca
     2461 aaccaaaata attcaatcct tgaatatctg ataagataat ctccagttca tcgtaaaaac
     2521 ccttagccct tagtttatct aatagaatag ccaaagaatt agtttcttgg agaaacttga
     2581 cgatataagc tctccgagta cgaacatact cgcgattatt gccatgagtt gcaaaaaatt
     2641 cccacatcac aaatttttca agcttgctat gcttagaatc cccctgagct tgtcgtaaag
     2701 catgaagacc acgaccatta attttataac cttgaaatcc atctttttca ccattagtaa
     2761 aggtacgctt aatcgtttgt gaatcaacca aaccaacatt ttttagccaa ttacaaatac
     2821 cgcgtgcata tttatcactt gttccttcta tatcagcttt aataagtttt ttctctgatt
     2881 tagtggcaga tcctaaccaa tcaaacataa tatcttcatt ataggaagta aagccttttt
     2941 caccacgaaa accaagctgc tcacctaaat aatatttagt acaataagta ccgctatcag
     3001 ccaataaaga taagatttgt gtagctggcg ggtatgacaa cagtgccttt cttaaaatag
     3061 cagtttcttc ttccgaatta attattgccc tagaaaaatg caaccccttc gaagtaattg
     3121 aaaacatatc cgtttctcta tctaccgaca caaaattcag gctaacagcc catcttaaaa
     3181 aaccatctga tgtccaatta tccgtccaag ttttacctgt attttttgcc tgttgaggta
     3241 cgatgctgat ttgaatcaaa gaatctgcca ttgcatctga acgctttcgg ggagatttgt
     3301 tattcttatc ctttgatgtt ccaactaatt ctaaatatga aaatgattga atcccattaa
     3361 tcagtttgtt tctgagtgat tctcgtggta cttcaaagaa atctgtaccc aaccataagt
     3421 tcttattttc ataagagctc cttaatctta tacttattat ctttattata gcatataatt
     3481 aatccttcca gttagcatta tcacaaagca acaacatttc ttatttaatg gggctactat
     3541 gtagctattt taatacatgt ttttacctca cgaaaacacc cccacttgtc aagtctgta
//
LOCUS       DARYJX010000080         3302 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYJX010000080 DARYJX010000000
VERSION     DARYJX010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3302
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1180..2694
                     /locus_tag="TU257_001981"
     CDS             1180..2694
                     /locus_tag="TU257_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0834944.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
     gene            complement(2987..>3302)
                     /locus_tag="TU257_001982"
     CDS             complement(2987..>3302)
                     /locus_tag="TU257_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HEL0834945.1"
                     /translation="TELESRPVYVWTEKHIQAHFLTCFIALVHLRLLQHQIDWQMSPE
                     RIITALNSAKVTPLQDNYYRLQESLDMQELNRLLGIEWAKGIVKFEELKHYAKNPYTT
                     LK"
BASE COUNT          943 a          520 c          632 g         1207 t
ORIGIN      
        1 tttgaaacca cattagtgcc tgcaaataaa tctaaaaaaa acttcttcat caccagtttt
       61 atgtttgtct agcatggtct taatttctgt caacaataat tttttagaac caatatatct
      121 cattctacat ccttaatcat cctttagttg tttcattata gcatattcat gttgaagttc
      181 caatatttta tttgaaaaat tatcttttgc tgtatttctt tattgtagtt tttaagctta
      241 gtttatatgt tgttgattaa agggaagaag aacttaggtt atctaaattg aggaattcgt
      301 ctgtaggtaa caatgtatta tgtggccgag agatttattt tatatattaa tgagatataa
      361 gacccctatc ccgtccagcg tgacagactt gctatggaaa agcttatttt gaggctgtct
      421 gaggcttgct tatgtgtgac aagcatttag gctagaacgc tcaccttttt tactgcaagc
      481 aaagctttag aagctattgc aagatacttt taggcttgtt actaagcggg tcatctctat
      541 catctcctag agagtagtgg aggctatgac agtttagcat atatggtttc tctaatgatt
      601 tgacgatgta aaaccataac tactgttatt gtagggatta tgtataatat gtataaaaag
      661 agaagggctt gtttctcagc gttatcattt tacctataat gtcgctgcca gtttgcaagg
      721 ctgctgagat tagtagcttt ttggctattt ttctcatctt ttgtcttatt tttattaaaa
      781 ataatgaatt tataaagata atttttcaaa gaatagtctt taagttgaca gtagtatcat
      841 gtggcgattt ttgtcttggt ttttgcattt atttcggttt ttttatcttt aattaagtta
      901 ctaatattct gattatgtta gtaaaatgac attctcataa aatgtctaaa aaaggctaat
      961 ttgtcaaggt attatcataa ggcttgattt tataagctat tgactgtata ctcttatagg
     1021 ttattttata aaatattttc agtctttttt atttatcatt ttcagatgat ccttgaaagg
     1081 aagcagtcgt tattttttgt gtattttttt tagttgactt ttaaatccta tcaactaaaa
     1141 tgtatatggt catacaaact aataaggaga gagattattt tgttagatta ctatttagaa
     1201 agagatattg ttgagcgaaa actaatattg gctgtcttat tgacagaaaa agagattaca
     1261 cttgattcat tgtgctcgca gacgtcaata acccctcgaa aggctaagga ataccttaat
     1321 cagattaatg cactatttga caaagacctg tctattactg tattgaagtc aggcattacc
     1381 tgtgagtttg atcctaataa caaggagaag tattttcaca gtatttatgc atcatctgat
     1441 acgcttaaaa tgttgaagtt tctgttgacg gataattaca ggacaaagtg tctgacaact
     1501 ttcatcagaa gacagtttat ttccaaatca aaggcctatc atcttgtcaa taagctaaag
     1561 ggctacctgc aatccattca tttggatatc gatgattacc gggttatagg ggatgagtac
     1621 cggattcgct acttaattgc catgcttcat aaggagtatg ggtttgctgt ttatgagatg
     1681 acacctaagg atatggaaat tattcatgcc tttatttttt taacccctac gcggttaaag
     1741 cccactgttt tcttggacaa gaaattttat ctttttgata ttttactcat gctgtcttgg
     1801 aagaggcaga attatgatgt atccttacca cagcttactt tatttgatcg tttaaaagaa
     1861 ttatctattt ttgagcaaat cagttgctat gctaagcaag aaattgagac acgtactcag
     1921 gttgtgttta attctggtga cttagattat ctttacttgg tttatcttac agttgatagt
     1981 tcttttctta tgcattattg gaatgacaag caattacgtc ttgtctacaa tatcttagaa
     2041 gaagatccgc tgtataagga gcttgttaat cgcttggaaa tgttgtttgg tcgtcagctt
     2101 catttaaggg atcagatgta ttttttgctt ccctttttca gaagatgtct ctttcaattg
     2161 catgatttga ttagctttca ggattactat tcaaagaggt atcaaggcag tcagctgctg
     2221 ctagaaaagg ttgaggagca aatcaaggac tggctgatgg ttagctacca gtcagaaacg
     2281 ctctcaccag ggcacctgca ttttatgtgc cttcatttgg agcagatgct tgagctgtcc
     2341 ttgccgcctg tagaggtcat catcgttgaa aacaagagag cattaggtga tgtcttgtct
     2401 tactttgtta tctcaagtat tccttcttat aaggttaata ttactcgtat caacatgcta
     2461 acagatagtc tggaaaatta tgagcaggct cctgattttg tgattacgag tgataatatt
     2521 ttgccttttc ttgaggagca gcaggtattt ccagataaga gcgtcttaat tggtatgagc
     2581 atggattaca ttaaggagca gggaaaaaca gtggtaaaat caattctgaa ctttcatcgt
     2641 aagcattacg agcagctttt agagcagctc ttgattggag atagggtaga gtaagttttt
     2701 ttgctaagca agtggtataa ggctgctagg tttttctttg gaccattttt tgtgaggatt
     2761 tgctttagcg atacctgttt tgattggctt actgctgatc gtgataacac ctatgctaaa
     2821 tagcagcaat caatagctcg tgcctatttg gtacaatatt tctgaaaaat ccacttgtga
     2881 taagcctttc aagtggattt ttgttataat cccgacttta tcacttaaaa acaagtaaag
     2941 accagctaac cccttgtgtc ccaagggatt ttgctggtct ttaaatttat tttagtgttg
     3001 tatatggatt tttagcgtaa tgtttgagct cttcaaactt aacgattccc ttcgcccatt
     3061 caattcctag cagtctgttt aactcctgca tatcaaggct ttcttgaagt ctgtagtagt
     3121 tatcttgtaa cggtgttacc ttggcactgt ttaaggcagt aatgatacgt tcaggactca
     3181 tctgccaatc tatctgatgt tgaaggaggc gtagatgaac taaagcaatg aaacaggtta
     3241 gaaagtgagc ttgaatgtgt ttttccgtcc aaacgtaaac aggacgactt tccagttctg
     3301 tt
//
LOCUS       DARYJX010000081         3247 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYJX010000081 DARYJX010000000
VERSION     DARYJX010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3247
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1115
                     /locus_tag="TU257_001983"
     CDS             <1..1115
                     /locus_tag="TU257_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0834946.1"
                     /translation="SLCRNKYIDPDKFKRNEVSCYSIRESVDELNTVCRDTMFYHLSK
                     HIPRQGISMLSLVEALMFKDKYKKIIVRWINYLVDFKYLEKNRGYIFSKKEKIDEIDL
                     LKKWDVLESKWNKDAMPINVFQYFRNNARELSALLKEDINANEILFVEGSDVVAKDLY
                     SKTAIARYLNELIVKKIKEFNGNEDLTILELGGGTAATTEKIIDNIKYGKYIFTDISP
                     YFIENAKSNFDEYKNIEYKIIDIDDYASYKQIESKVDFIIAVGVLNNAKNIEKTLSYI
                     RGFLKDDGFLIIVEAVDESPEILISQVFMMSEPDDVRMKKNITFLKMEQWMEIFKNQR
                     FELILFEPGYENYLENFNQKLFVLKKNRGENHENRE"
     gene            1099..>3247
                     /locus_tag="TU257_001984"
     CDS             1099..>3247
                     /locus_tag="TU257_001984"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012873.1,HMM:NF036900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834947.1"
                     /translation="MKIENKLIELYRKGLEVFIEGDKLKYKSTCGMPSEEDIEFLKIN
                     KTSIIDILNKNDGASRYSLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPL
                     LDIDRAEKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRD
                     KLKGKSYNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKT
                     IMDNSYDLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERI
                     QLRIDENTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYI
                     KSDVVNDFTSTELLEFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVE
                     RRDAIFPFVFTSALGIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRA
                     DAFSKELSNSIAEDYSNLLNCFFDLEYFKKTLTEMYDENEMNDVLADKSDFDRVKYRV
                     IEHSKKFYNKNVFDAGEVRKILEERNLFSNQTMLKTLIEIKGDIIYKDFNNIPGNVVL
                     GEYHWILNKWEKHLDKAGFIKDNGDFYVVSEKGDELLKLNFDIELLKNSWDYSIGNSE
                     VIDYIIKTSENVINIFSGKIKPISILFPEGSSKIVESIYGNNIFCNYYNNIIRKAIEE
                     IIDLDSHKNINILELGAGTGNTTKEILKMLEMKN"
BASE COUNT         1323 a          303 c          581 g         1040 t
ORIGIN      
        1 aatcattatg taggaataaa tatattgatc ctgataaatt taagagaaat gaagtgtcat
       61 gttacagcat aagagaatct gtagatgagt tgaatacagt ttgtagagat acaatgtttt
      121 atcatttgag taaacatata cctagacaag ggatatcaat gttatcatta gtggaagctt
      181 tgatgtttaa agataaatac aaaaaaatta tagtgcgttg gataaattat ttggtagatt
      241 ttaaatactt agaaaaaaat agaggatata ttttttctaa aaaggaaaag atagatgaaa
      301 tagacttgct taaaaaatgg gatgtgttag aaagtaaatg gaataaagat gctatgccta
      361 taaatgtatt tcaatatttt agaaataatg cgagagagtt aagtgctcta ttaaaggaag
      421 atatcaatgc aaatgaaatt ttatttgtag aaggtagtga tgtggttgcc aaagatttgt
      481 attcaaaaac agcaatagca agatatttga atgaattaat agttaaaaaa attaaagaat
      541 ttaatggaaa tgaagattta acaatattgg agctgggtgg aggaacagca gctacaacag
      601 aaaaaataat agacaatata aaatatggaa agtatatatt tactgatata tctccatatt
      661 ttatagaaaa tgctaagagc aattttgatg aatataaaaa tatagagtat aaaattatag
      721 atattgatga ttatgcatct tataaacaaa ttgaaagcaa agtagatttt attatagctg
      781 taggagtgct aaacaatgct aaaaatattg aaaaaacatt gagctatata aggggatttt
      841 tgaaagatga cggcttcttg attattgtag aagcagtcga tgaatctcca gaaattttaa
      901 tatctcaagt atttatgatg tcagaaccag atgatgttcg tatgaaaaaa aatatcactt
      961 ttttgaaaat ggagcaatgg atggaaatat ttaaaaatca aaggtttgaa ttaattctat
     1021 ttgagccagg atatgaaaat tatttagaga atttcaatca aaaattattt gtgttgaaaa
     1081 aaaatagagg tgaaaatcat gaaaatagag aataaattaa tagagttgta cagaaaaggt
     1141 cttgaagtat ttattgaggg agataaatta aaatacaaat ctacttgtgg tatgccctcg
     1201 gaagaagata tagaattttt aaaaataaat aaaacttcta ttattgatat attgaataaa
     1261 aatgatggtg cttctagata ttcactagat attgatgaat tacctttaac agaaattcaa
     1321 agtgcatatt tattaggtag aagaaatcat tttgaacttg gtggtgttgc cagtcatgtt
     1381 tatatggaag taatattacc tctattggat atagatcgag ctgaaaaggt ttggaatgat
     1441 ataatactaa agcacgatgc attacattca atatttacat caaacaatac tcagaaagta
     1501 ctgaaggaat ttgcttacta taaaatcgaa tgcaatgagg gtgcagatat aaaagaaaaa
     1561 attgcattaa caagggataa acttaagggg aaaagttata atgcagatat atggccacta
     1621 ttcgatataa gtgtaagtca gttagatgac aatagtttat tgcatttatc atttgatttt
     1681 ttgattttag attgggcaag catttggatt ttattaaagg aatttgaaga gtgttatttt
     1741 gacggaaaga cgattatgga taattcttat gatcttaaag aaataagaac gagtcaactt
     1801 aaactgaaac atagttctaa gtatttatcg gataaagatt tctgggaaag aagaattcct
     1861 tttttgcctg acgctccact attaccaatt aaaaataaaa tagtcaaaaa tggttttgaa
     1921 agaatacaac ttagaataga tgaaaatact tggtcgaaga taaaatctaa tataagtgag
     1981 attggtgtca cgcaaacatc tttcttggtg acaatattag ctcttgttct taatagatgg
     2041 agttctaatt ctgaatttac cattaattta acaactatga atagaccaaa ggagtatata
     2101 aagagcgatg ttgttaatga ttttacatct acagaacttt tagagtttag aatggaatct
     2161 ctgcaaccat tctatgtttt attaaaacac atacaacagc aaatgattga agatttgcaa
     2221 catgaaacat ttacaggagt ggaagttact cgtgaagtta ggaaaaatgt agaaaggaga
     2281 gatgctatat ttccatttgt tttcacaagt gcattaggaa taaaagcttc agaatataaa
     2341 tatattagtt tacaaaaaga aggtttgagt gaaactcctc aagtattaat ggattgtcaa
     2401 gtaatggagg taaatcatga actaataatt aattttgact taagagcaga tgctttttca
     2461 aaagaattat caaattcaat tgcagaagac tattctaatc tattaaattg cttttttgat
     2521 ttagaatatt tcaaaaaaac actgacagaa atgtacgatg aaaatgagat gaatgacgtt
     2581 ttagctgata agagtgattt tgatagagtg aaatacagag ttatagaaca ctcgaaaaaa
     2641 ttctataata aaaatgtatt tgatgctgga gaagtgagaa aaattttaga agaaagaaat
     2701 ttattttcaa atcagacaat gttaaaaacc ttgattgaaa ttaaaggtga tataatttat
     2761 aaagatttta ataatattcc aggaaatgta gtacttggtg agtatcattg gatattaaat
     2821 aaatgggaaa aacatttaga caaagctgga tttattaaag ataatgggga tttttatgta
     2881 gtttctgaaa aaggggacga gttacttaag cttaactttg atatagaatt actaaaaaat
     2941 agttgggatt atagtatagg taattcagag gttatagact atataataaa aacatctgaa
     3001 aatgttataa atattttcag tggaaagatc aaaccaatat caatactttt tcctgaaggg
     3061 agttctaaga tagtagaatc aatatatggt aataatattt tttgcaacta ttacaataat
     3121 atcataagaa aagctattga agaaataata gatttagatt ctcataaaaa tataaatatt
     3181 cttgagctag gagcgggtac aggaaacaca acaaaagaga ttttaaaaat gcttgaaatg
     3241 aaaaatt
//
LOCUS       DARYJX010000082         3205 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYJX010000082 DARYJX010000000
VERSION     DARYJX010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3205
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..219
                     /locus_tag="TU257_001985"
     CDS             <1..219
                     /locus_tag="TU257_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0834948.1"
                     /translation="MSRKGNSPDNGMMESFFGILKSEMFYGFEKSYHSLDELEQAITE
                     YIFYYNNKRIKTKLKGLSPVQYRTKSFH"
     gene            221..1315
                     /locus_tag="TU257_001986"
     CDS             221..1315
                     /locus_tag="TU257_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL0834949.1"
                     /translation="MSCPTFGGQYKVSQTLGSDFDLPYYIYSKIKRNKTEKVISPLKI
                     GLKITNACYFRCPYCFVSKEEDYLLFDHLKIIIDKLPQLPFEVYLTGGEATLHPEFPK
                     IVDYLVDLGILVKLHTTGVITEKSRNYIISNLEKFSSIQISIDSIKNFDKLRPSHIVI
                     NPLEQICSFVQKCLDRDYKKLLVNIVISSLNIHELDEVIDFCFKQGLLRIQLSSIFSI
                     HNRLLVSDEKYAAHYNKLIEKFSCLGVQFLTSPFCHPWSLAIKHGIEYHSPLYCPAQK
                     TEFEIDMYGDVYPCPFLHDKIHLMGNLISDDFETIWYSGVEQLNRRAWSSNDSCKNCK
                     LFNDCGGGCYAMAFVSQLEYDKRCILHANQ"
     gene            1302..1562
                     /locus_tag="TU257_001987"
     CDS             1302..1562
                     /locus_tag="TU257_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL0834950.1"
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINS
                     LRIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            1555..2454
                     /locus_tag="TU257_001988"
     CDS             1555..2454
                     /locus_tag="TU257_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834951.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKAIFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            2444..3184
                     /locus_tag="TU257_001989"
     CDS             2444..3184
                     /locus_tag="TU257_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834952.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPIFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
BASE COUNT         1017 a          470 c          605 g         1113 t
ORIGIN      
        1 atgtctcgca agggtaacag ccctgataat gggatgatgg aatccttctt tggcatttta
       61 aagtcagaga tgttctatgg ctttgagaaa tcctaccact cactggatga gctcgaacaa
      121 gcaatcactg aatacatctt ttactacaac aataaacgaa tcaaaactaa actaaaagga
      181 cttagccctg tgcaatacag aactaaatcc tttcactaat atgtcgtgtc caacttttgg
      241 gggtcagtac aaagtatcac aaactctggg gagtgatttt gatttacctt attatatata
      301 ttccaaaata aaaagaaata agacggaaaa agttatatct cctcttaaaa ttggtttgaa
      361 aattaccaat gcatgctatt ttagatgtcc gtactgtttt gtatcaaaag aagaagatta
      421 cctcttgttt gatcatttga aaataataat agataaacta cctcaacttc cgtttgaagt
      481 ttatctaact ggtggtgaag ctactttaca tcctgagttt cctaaaattg tggattatct
      541 tgttgatcta ggaattcttg taaaacttca tacaactggg gtaattactg aaaaaagtag
      601 aaattatatt atttctaatt tagaaaaatt ttcttcaata caaataagca ttgattctat
      661 caagaatttt gataaactta gaccaagtca tattgttatc aatcctttgg aacaaatatg
      721 ttcttttgtg cagaaatgtt tagatagaga ctataaaaaa ttgttagtga atattgttat
      781 tagctcgtta aatatccatg agcttgatga ggtcatagat ttttgtttta aacaaggatt
      841 gttacgtatc caattatctt ctattttttc tattcataat agattattag tatctgatga
      901 aaaatatgct gcacattata ataaattgat agagaaattt agttgtttag gtgttcaatt
      961 tttaacatca cctttttgtc acccatggtc tcttgcaata aagcatggaa ttgaatatca
     1021 ttccccactt tactgtccag ctcaaaaaac ggaatttgag attgatatgt atggagatgt
     1081 ctatccttgt ccattcttac acgataaaat tcacttaatg ggaaatttaa tttctgatga
     1141 ttttgaaact atttggtact ctggagtaga acagttaaat agaagggctt ggtcaagtaa
     1201 tgatagttgt aaaaattgta aattatttaa tgattgcggt ggagggtgct atgccatggc
     1261 atttgtttca cagctagaat atgataagag gtgtatatta catgcaaatc agtaaaaatt
     1321 ggtttattag atttgaacct aattttcaaa cgacacaaaa tacgatatta tttaataaag
     1381 taagcggaga gctgtttgag gtaacagaag tttactatga ttgtatcaat tctctgagaa
     1441 ttggtgtcga ttttcaagct cttctgatgg aaaagtatgc tgtcaacgca ggggacgtga
     1501 ttgacgtaga agatacgatt ttaaaaaatc taatatcgct aggagtaatt cttaatgagt
     1561 gacatcacta tacgccatgt caagaaaagc tttcatcatc aggtagtctt agatgtgcct
     1621 agttttgatg taaagcgtgg agaaattgtt gctatcgttg gtgcaaatgg tgcaggtaaa
     1681 tcaactttga tcaaaatgat ctctggttta atgctgcaag acacaggatc tgttttggtt
     1741 tatcatcata aaaatacttc agcagctatt catcgtgatg tgaaatttgt cttagaaagt
     1801 ggtaggggct attacgagta tctgactgca aatcaaaata ttgattactt tttacatttg
     1861 aataacctgt cacgtagcca agtcaaagaa gaattggcag agttgtgcca aaaattggct
     1921 tttaatccct atactgatcg gttggtttct gaattatccc aaggcacaag acaaaaattg
     1981 tctttgatta ttgctcttct ttgtcagccc aaggttctgt gcttagatga gccaacaaat
     2041 ggtctagatg tggttgcaaa aaagcaattt gcaaccttgt tgcttgagct tagtcaaaaa
     2101 aagcaaacga ttatcctgat gacgactcat gatatctttt ttgtaaaaga gctatcagca
     2161 agaatttgtg tcatgagtaa agggaagatc aaaaaacagg ggagtttttc agaaattttc
     2221 ggagaaaaca atacgtggat gaaatataga atcggtatcc ctaagtttga gaaggctatt
     2281 tttgatcagt tatttccttt cttagcttat caggtagaag atgagagatt agtcgtcgaa
     2341 gtgacagata gtcagacaaa acatcatatc tttgagcatt ttgagattat attttttgaa
     2401 gaagttgaaa aaagcatcga agagctatta tatgaggtta ttactgatga ttaaagaaat
     2461 acaaagggag ttgaaaagac aattgcagga gatgatgcaa ttcaaattca atttattttt
     2521 tgcaaacttt ggtattttga tcatggtgtc atcttatctt cactattttg aagatacgca
     2581 gagtcagttc ttgttattat gtctattatt cacttggtat tttacgagtc atagcctcac
     2641 acatccaatc ttttttattg aagatgacct ttatgataga acgttgatca gtgttattca
     2701 aagcagcaag agtgtttttc atgtcctcat gcttaaaatt attgttcaac tattggtgga
     2761 tttagttaag gcaataccta ttgttattat gttatcactc cttaataata ttgactttcc
     2821 agaaagtagc ttgagggtga tgggaagctt tgttgcctgt tttttgacag tcattagtac
     2881 atacggtctt ggcttttgct tatccagtct ctgttttgtg tttaatcgta cctccagtgt
     2941 tactgcgtta atttcttatt tcatgctata ctttaccggc atactaacgc cattagatgg
     3001 ctcacttggt cttattggaa aaatgttccc ttattatgct ttgagaaatg ctattatgtc
     3061 tccttcatat cagagcgtat gttggattgt ggcttacggt atgatatatt ggtcggtcgg
     3121 tacgttattg ttttctaggg cattgacaat ggctaaaaaa agagggagtc tttttcatgt
     3181 ttagtgaaat gaaacgatat atgac
//
LOCUS       DARYJX010000083         3150 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYJX010000083 DARYJX010000000
VERSION     DARYJX010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3150
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..290)
                     /locus_tag="TU257_001990"
     CDS             complement(<1..290)
                     /locus_tag="TU257_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL0834953.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEK"
     gene            complement(250..1428)
                     /locus_tag="TU257_001991"
                     /pseudo
     CDS             complement(250..1428)
                     /locus_tag="TU257_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            1485..2042
                     /locus_tag="TU257_001992"
     CDS             1485..2042
                     /locus_tag="TU257_001992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834954.1"
                     /translation="MSNFWGAVQSDSDDIKYRIDSYNRYGIDGLAGKLYTNYIVGKIS
                     NDELNYGLQKIFAKLISTKMGRMVPIENNNGSPYVDSGNAGLITVLILLDPEKYKDII
                     IELADSLQFEFAQRPGYFNGMLGVAEVLLNVYSQIYKKDDYLFYAEKLLLNTSFYVEH
                     RLVEKEQFIQVFNHYIEVINESTGK"
     gene            2023..>3150
                     /locus_tag="TU257_001993"
     CDS             2023..>3150
                     /locus_tag="TU257_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL0834955.1"
                     /translation="MNLLVNNRFFRYTSISTFLNQFGSSIYNIVFIIYVASTYHSKTL
                     VSIANIILMIPILFQLLIGQYADRIRNRAKWLIWGGISQSILFMIIAYLTNQKSYLVF
                     SIICLINIISDCISNLLSGISMPIFKHHIPQDELMTAYSLRNIISFICGIGGQIFGIW
                     LLEISNKNFGFVAIINAFSFLISSIILVSIKSLLINNKEKITRHSFSRNFLEMYDASK
                     GIFSTKSDSQFIKLITTVIISNVLGSAIIPIFNLYFLENKWQNFSYGQTLLILNTTMI
                     LGNILGSLFPKDFFSRLSLKKILALELYSFALIGIFSFLKFPFIFVLFVFSFNCFLVG
                     KFNPKFSATLMTNVPDNMLAQVSSFISFLVMISIPIGTSVFS"
BASE COUNT          977 a          515 c          480 g         1178 t
ORIGIN      
        1 tctttctcag cttgtttacg atacttgtta gcattagcta cgtaatctga taaatcttca
       61 tgacgtagtt ttttaacgac atcctgataa gtcattttgt tctcttcaga atacttagta
      121 taaaaatcaa acaattcctt ttgtaactca aaagcctgtt cattatataa cttctgcagt
      181 tctgaaaaga catctaaatc agttctgtct aaataactta gaatatcttt ttgacgcttt
      241 tgccagtaat taaggctttt ctgccgttgg ttcttcttga ccactagcat cacctaccaa
      301 tctaggctcc ggtaaagatt gctttttatc agcttcttct ttcaagcgtt caagctctgc
      361 ttcagcatct actcctgtga cagtatttaa gatttcaaag atagtctgat cgctaacaat
      421 gccataaaga ttttgtgcag ctgtaacaat ttcattatcg ttttgaggaa gattaggtgt
      481 gaaaactata ctcgtatcat ttacaaggct atatgtagtt gcttcattcc ctttgatggc
      541 ccagatatta gctgctaagc gtaagcgtcg cattaatcct tttttaaaca acctctcttg
      601 cttctcgcga tagttgtcag aagccataag cttatacttc attgattcac cagattgaac
      661 tcctgaaaat ttcatatctt gtgtatctgg cgtaaaagta aacctcaaaa tgtctgcaac
      721 taatctattt ttgtaggctt cgctaccggc ggtatcatac tcttttttga gaaagtacgc
      781 ttgcggttta acgccatttg gattaggatt atcgtctaaa attaacactt gggctttttt
      841 aaacccaatt gagatcgcta aacgaccatt aggatttaat cggccatcat ctaagtagtc
      901 attctcatca gctcctgtgt aagcattacc agctattaca agcaacgcat tgactgaatc
      961 ttgttgaaag ttagcaagct ctgattgaga taaatcatag gcgtcaatat tatcaagtac
     1021 agactcataa gcccccgttc gctcctcgtt attagcgtat tcgttgactg gtacacctct
     1081 aaaaaaatgt ccttcataat cttttaatcg catacctttt gtttcaaggt tatagtcttc
     1141 gtaggtataa attgtgtcgg aagtatatgc tttgataatc tgtttacgtt tacctgagcc
     1201 gtaatctatg tcgtagaaat gaacggccat caacgaattt cgctggtatg tatcatcata
     1261 gataacaaaa gtttgctcgg ccgggagctg gtagagtttt acttcggttt ttttgtcatc
     1321 tattttctca acagttaaca gctcgtaggc tcttccataa attgataaat ctgtttttat
     1381 tttgacgttg tggtagtcct cattgtttct gaccgacata aggtcaatag tgaactgccc
     1441 cccaaaagtt agacataaaa atagcccccc aattgttaga ttttatgtct aacttttggg
     1501 gggcagttca gtctgattca gatgatataa aatatcggat tgattcatat aatagatatg
     1561 gaattgatgg tttagcaggt aaactttata ctaactatat tgttggaaaa atttcaaatg
     1621 atgaacttaa ttatggttta caaaaaatat ttgctaaatt aatttctact aaaatgggta
     1681 gaatggttcc aattgaaaat aacaatggat ctccttacgt agattcagga aatgctggtt
     1741 taattactgt tttaatatta cttgatccag aaaaatataa agatattatc atcgaattgg
     1801 cagatagcct ccaatttgaa tttgctcaac gacctggata ttttaatgga atgctaggtg
     1861 ttgctgaagt tttattaaat gtatattcac aaatctataa gaaagatgat tatttatttt
     1921 atgctgaaaa attgttatta aatactagct tttatgttga gcatagacta gttgaaaaag
     1981 aacaatttat tcaagtattt aatcactata ttgaggttat taatgaatct actggtaaat
     2041 aacagatttt tcagatatac ttctatatct acctttttaa atcaatttgg ctcttcaata
     2101 tataatattg tttttatcat ttatgttgca tctacatatc attcaaaaac tcttgtaagt
     2161 atagctaata ttatattgat gatcccaata ttgtttcaac ttttaatagg tcaatatgct
     2221 gatagaataa gaaatagagc caaatggttg atttggggag gaatctctca gtccatatta
     2281 tttatgataa ttgcttattt aaccaatcag aaatcatact tagtattttc tataatttgt
     2341 cttattaata ttatttctga ttgtatatct aatctattat ctgggatttc gatgccaata
     2401 tttaagcacc atatccctca agatgaatta atgactgctt actcgcttcg aaatattatt
     2461 tccttcattt gtgggatagg tggacagata tttggtattt ggttacttga aatttcaaat
     2521 aaaaactttg gttttgttgc aataataaat gctttttcct ttttaatatc atcaattatt
     2581 ttagtatcta ttaaatcgtt attgataaat aataaagaaa aaataacaag acacagtttt
     2641 tcaagaaatt ttttagaaat gtatgatgcg agtaaaggaa ttttttcaac taaatctgat
     2701 agtcaattta tcaaattaat aacaactgta atcatttcaa atgtactagg atctgcaatt
     2761 atccccattt ttaatctata ctttctagag aataaatggc aaaacttctc ttacggacaa
     2821 actttactaa ttctgaacac tacaatgatt ttaggaaata ttttaggaag tctatttcct
     2881 aaagattttt tctcaagatt atctttaaaa aaaatactag cattagaatt atatagtttt
     2941 gcattaatag gaattttttc atttttgaag tttccattca tttttgtact ttttgtcttt
     3001 tcttttaatt gttttttagt agggaaattt aaccccaaat tcagtgcaac tctaatgaca
     3061 aatgttcctg ataatatgct tgctcaagta tcatcattta tttcattctt agttatgatc
     3121 tccattccga ttggaacaag tgtcttctca
//
LOCUS       DARYJX010000084         3100 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYJX010000084 DARYJX010000000
VERSION     DARYJX010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3100
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1400)
                     /locus_tag="TU257_001994"
     CDS             complement(<1..1400)
                     /locus_tag="TU257_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0834956.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSLRSISDDKGIISD
                     GDTVIGHIETKKEYLRS"
     gene            complement(1403..2155)
                     /locus_tag="TU257_001995"
     CDS             complement(1403..2155)
                     /locus_tag="TU257_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834957.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2486..2965
                     /locus_tag="TU257_001996"
     CDS             2486..2965
                     /locus_tag="TU257_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL0834958.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT          997 a          570 c          579 g          954 t
ORIGIN      
        1 gatcggaggt attccttttt agtttcgata tgacctataa cagtatcacc atcactaatg
       61 attcccttat catcactaat actcctaaga gatgttaaat ttttgacatt ggtatatgat
      121 ttgcccaaaa tatccagctg tcgtaattga ctatcccctc tttgcttaaa gaaggcagtc
      181 tgattgtcct ttaattcagg caattgattg cccaaggcgc ggaaatcatc ttgagtgact
      241 aagtagacat agcctgtagt gactggacta ggatttagca aggattcttt ggttactaca
      301 atggtttctt tttgggatac ttcaaaagaa accatgctac tataatagac tagaaaatcc
      361 gaggcaggct tattggtctt ttcaacaata agtctgttaa aaacctcttt ttgattgtca
      421 atctctgaat tatcaaaatt aatatgagta tttttaggaa aaagctggtt agacattgcc
      481 tcgctattag cataaagcgc agttgttgtt gctattgcaa caaaggccat aacagctaag
      541 agggtaatat ttgccaagcc tacagcattt tgcttcattc taaaaatcat ctgagaggtg
      601 ctgacaaaat gctctggctg gtaaaaataa gccttgtttt gacgacgacg ctttaagtgc
      661 caagtcataa aggaaatgta aaagagatag gtcccgataa taacgataat aactgctata
      721 aaaaaccgat ataaagtgtc taatgctgtc agctttgtcg atgataagga gatgtaatag
      781 ccaatactaa gcaatatgat ggataaggct gctagtaata aattaccctt tggctctttt
      841 tcaccctgtt ctttatgacg aaagagcatt aagggagagg tctttctgat tttaatcaag
      901 ccaacaacct ctaataaacc aaagatagca gcaaagatta aagtggtgta aataaaagca
      961 acgggattga tttgtaattc taaatggact gctccgacca gattagcgaa aatcaaataa
     1021 aagacgtgtg aaaaaatagc tgataggata cttcctacga ctactgtccc taagtacata
     1081 aaaacaagct cgatcgttga gactaaacca acctgctttt tattcattcc caaaatattg
     1141 tacagaccaa attctcgact tctttgcttt agtaaaaaat tatagctata aatctccata
     1201 atagtggcaa agatgattaa aacaaagatt gctagtccta atagcataaa cccatgtctc
     1261 atcgattctg atacggggct catcatgata atcaagacaa tacaattgag catatataaa
     1321 acagtgcttg ccagtaaaaa aggagctgtg acggataagg actttcgtag attattccaa
     1381 gctagtttga gataaaacat ctttattcac ctcctaaaag accggccatg gcaatcgaga
     1441 tgtctttgct aaattctaaa ttcgttttat ttccacgata gatttggtgg aaaatacggc
     1501 cgtccttgat aaacagtact cgcttagcat ggctagcagc attggcagag tgtgttacca
     1561 tcaagagtgt ctgaccgtct aggttaatgg cctcaaaaag attgagaata tcctctgaat
     1621 tgcggtaatc aagtgctgct gttggttcgt cagctaataa taattgcgga ttggtgatta
     1681 agcttcttgc aatagcaacc ctttgctttt gaccaccaga aatttcaaat ggacgtttat
     1741 ctaaaagcgt ttcaatgcgc agcttagggg caatgatgtt gagccgtctt tccatttctt
     1801 taaatggctt acggtttaaa acaaggggta aaaagatatt atctctgatc gatagggtgt
     1861 ctaggaggtt aaaatcctga aaaacaaagc ctaggttttg aagtcggaaa ttagctaggt
     1921 caccctcctt aatttttgta atgtcagtgc cattcaataa aacagatccc ttggttggtt
     1981 tttccagagt tgccagaata tttaataggg ttgttttccc tgagcctgac tctcccatga
     2041 tggcaataaa ctcacccttg tcaaccttaa aatcaacatc ttgtaaggct ctagtttctt
     2101 cctttgaaaa gcgtgtccga aaaaccttct ctaaatgatt aatttctaat aacatatgaa
     2161 actcctttgt gtctattata ctcttttagc tttaaatata gccactatcg tgacgtattt
     2221 agctagtgat gcatttagtg ccttttgtca gccttaacca ctccttcttt catgaagcag
     2281 cccagctctc aacaagaatc gtcttagctg actgaaccta ttgctctaaa ctcttttttc
     2341 tttacagctt atagtttacc ctaattaata gtctggttag cttacaagat ttgatgggtg
     2401 acttacagat ttgtaagttt tataacatca tttttcttat cattttgata taatgaaagg
     2461 agaattctat ttaggagaag cgtcaatggc taagaaaatc aaaaaaacgc tagggactgt
     2521 cggaaagctg ttttccatta tccctgatac cactgaaatt ataggaaaaa cgatagataa
     2581 cacccgtccc attatcgaaa agcatatgga acaaaagcat gaaaaggaaa tgcagctaac
     2641 gcttttagat gatgtgatta atttacctgt tgataaagcg caaaagcatc tggaacagct
     2701 aggttttgtt gtcgcactat tgccggtcaa gcctagtaaa aaatggatac atgctagctt
     2761 aaatgaggtt gtttccatgt cacctaagcc tggaaagcat aagctgggaa gcttagtaaa
     2821 gctttattat gttactgtag atgtccttga gaaaagtcag gctattttag atcaagagac
     2881 cctaaaggct gtcgaacgaa atcaaaaaat cgctgatacc atcgaagctg ttaagcaaat
     2941 caagcttcct tttaaaaaga gataaggcta tactgtaaaa aataagctga taccgttagg
     3001 atcagtttat tttttatgtt gtgactttaa gtctatctcg cttagcaggt gccaaacaaa
     3061 taaaccaccc gttatgtacc gaccttcaat ggttaaagtt
//
LOCUS       DARYJX010000085         3089 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYJX010000085 DARYJX010000000
VERSION     DARYJX010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3089
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1243
                     /locus_tag="TU257_001997"
     CDS             <1..1243
                     /locus_tag="TU257_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0834959.1"
                     /translation="TADKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQ
                     RANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEK
                     EELTTKLQELQKQAEEKTTEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQ
                     KEMELKQAQEQLKQEQKPHEGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKA
                     QLSETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAAL
                     QEQINKLKAEIEQKTKEIEALKQGMQSHQGQEKPKDPKTPETPKDPKTPEKNDQPQAP
                     EKRSVPWTALTPAKPIDTTKAPKSSAPSPQTGAATPKKQLPATGDTATPSFFTAAAMA
                     VLASVGVLNLSPRRKKNQNNR"
     gene            1660..2502
                     /locus_tag="TU257_001998"
     CDS             1660..2502
                     /locus_tag="TU257_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL0834960.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(2605..>3089)
                     /locus_tag="TU257_001999"
     CDS             complement(2605..>3089)
                     /locus_tag="TU257_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL0834961.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         1040 a          696 c          585 g          768 t
ORIGIN      
        1 tacggctgat aaagaaaagg cagagactga agctaaaaaa gcgaaagaag aagctaagac
       61 cgctaaagaa gctgctcatc aagaacaaga aaaagctaaa caattagaac aagctaatca
      121 acaggctaac caaagagcta atctggcaga aaaatctaaa aaagatttag aaactcaaaa
      181 agaaaaactt gaacaagaga ttaaagaagc tacagaagct aaaaacaaag ccgagcaaaa
      241 attaaaagac ctacaagatt cagctagtca aggcagtgaa ttgtctaaac agctgttaaa
      301 agaaaaagaa gaattaacaa caaaacttca agagcttcaa aaacaagctg aggaaaaaac
      361 aactgaaatt gaaaagctaa aacaagagct tgaagctaat aaacaaaaca gtggtcagct
      421 aggtcaacag gaacaaaagc ttcaagagca attgaataag gttcaaaaag agctgaaaca
      481 aaaggaaatg gagttaaaac aagctcaaga acagctgaaa caagaacaaa aacctcacga
      541 aggtggcgga gattctgacg cttccaaagc aagaatcact gagctagaaa aacaagttca
      601 aacactaacc aaggaaaagg cagatctgtc atcaaccctt gagtcaacaa aagctcaatt
      661 gtcagagact caagcaagac tatcagaagc tcaaaaacaa ttgactgctg ctcaagaaaa
      721 gttaacaaca cttgaagccg agaaaacagc gcttcaacat caagttgaga ccatttcaaa
      781 acagctatca gaaacacgtg accttagcga aaaggaaaaa gcagcactcc aagagcaaat
      841 caataagcta aaggctgaga ttgagcaaaa gaccaaggaa attgaagcct taaagcaagg
      901 catgcaatca catcaaggtc aagaaaaacc aaaggatcca aaaactccgg aaacaccaaa
      961 ggatccaaag actcctgaga aaaacgatca gccacaagcg cctgaaaaac gtagtgtccc
     1021 ttggactgct cttacaccag ctaagccaat tgacactacc aaagctccta agagctcagc
     1081 accaagccca cagactgggg cagcaacacc taaaaaacaa ttaccagcaa ctggtgatac
     1141 agcgacacct agcttcttta ccgctgctgc tatggcagta ttggctagcg tcggtgtcct
     1201 aaatctctca cctagacgca aaaagaatca aaacaaccgt taatgtagag actctcatat
     1261 ctggattgaa taacagcaaa cccgacatga gcaaaaacaa atgtctaacc aaaaatcact
     1321 gacattagta ctttaaccaa agcctttgag tcaagctaaa caggctgtcc tgcctattgg
     1381 cttgactcgt tttgtgattg tgaaacacac caaggtcaaa cctaccttgt cctccatttt
     1441 aaacctactc ttttctccca tacccacttt agcttacgca agaaggtgcc taatcatcac
     1501 ttttggtagc ttcgatgctc tatataaatg gatcaacaaa gataaatcat acaaaactgc
     1561 gagttgttcc tatagtcacg atagctctta cagatatgaa aagtaaatac agctattaaa
     1621 aatatggtac aataggggta cgatttttag gaggcatgta tggtttcagt tctttcacga
     1681 gtgattaagg gaataattat tgcgcttggc tttattttac cgggagtatc tggaggagta
     1741 ttagccgcta tccttgggat ctatgagcgt atcattgcct ttttagctca tatacgtgag
     1801 cattttgttg agaatgttct ctttttcctg cctgttgggg ttggtggtat tttagggatt
     1861 gccctctttt cttaccctgt tgactatctg ctcaagcact atcaggtacc agtcttatgg
     1921 ggcttcgctg gggccatcat aggaaccgta cctagcctga taaagacttc gacaaaaaca
     1981 tctcagcgtg accaagttga ttggctctgg ctagtattaa cctttgtcct atcaggactg
     2041 ggactttatt tcttaaatga tctcgttggg acaatacctg caagctttac cgcctttgtc
     2101 ctagctggtg ccttgattgc tttaggtatt ttggtacctg gtcttagccc gtctaatctt
     2161 ttattaattt taggacttta ctcacccatg ctgattggct ttaaatcact tgatttggta
     2221 ggaacctttt tacccattgc tattggtggc ttattaacca tgctagcttt ttccaagatt
     2281 atggattttg ctctcaagca ctaccattca cgcgtttacc actttattat cggtatcgtc
     2341 ctatccagca ccctgcttat tttaattcca aatagcagta ataaggaagc tatctcttac
     2401 gccggtgcag gtcttggcac ctggctaatg gctctgctat tatttggcct tggtgtctgg
     2461 cttggtctat ggatgagcca gcttgaggag aaatacaaat aacactcgat acaccagcaa
     2521 gtacctctaa cagcagcatt aagatcaaaa aaacgaatga ctagctctca gccttatcac
     2581 cagctgtgac tagcattcgt ttttttatat gtcatcatgc tgtcttgcct ctgtcacgat
     2641 ttctataaaa cggttcgtca attgagcagt tataccccag ataggctttt ctaaatgctc
     2701 atagagtaat acctgatctt gcatgtacct caacctgtac tgctctccat tagggatacg
     2761 atccaacgga aagtctgacg agattatcga ttgcatttgt aaaggataag caacaggagc
     2821 ttgcgccatg agctcctcca aaggcaccgt aaacaagcta tcaacctctt cattgaccct
     2881 aagccttctc caatcatcaa tagccagttc cgcaacaaag caatgaatgc tacgagtcgg
     2941 ctgaactaaa tagtcaatct ccccccaaac atgaacctgc tcaggctcta tattgagctc
     3001 ctctaccgtc tcacgaatag ccgcctgctg ataagtctca ccctcctcca cgcgcccact
     3061 aggaaaagaa acctcccctg gcttgaatg
//
LOCUS       DARYJX010000086         3053 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYJX010000086 DARYJX010000000
VERSION     DARYJX010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3053
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..220)
                     /locus_tag="TU257_002000"
     CDS             complement(<1..220)
                     /locus_tag="TU257_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL0834962.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCTG"
     gene            complement(240..1985)
                     /locus_tag="TU257_002001"
     CDS             complement(240..1985)
                     /locus_tag="TU257_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834963.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKLVESTMELIIGLPIVKAF
                     NKGDISLKNFNAAILSSKKVNLRIEKEYTPFNCLHLFSLKLASMCIVIIAGMMAINNK
                     IDISIMIAIFIFSFIMFSSVENINSATHVLEILDKTLDNLDKIKNADFLDDNGKDMEL
                     SSHNIVFDKVRFAYDKIPIIKDVSFEIKENTVTAIIGPSGSGKTTICNLISRFYDVSG
                     GSIKIGNVNIKNLTLSSLLSNISTVFQKVYLFNDTIENNIKFGNPNVSKEEIINAAKK
                     SHCHEFIMNLPNGYETIVGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPE
                     NEYLIQRAISNLSKGKTVIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLY
                     RDYMRIRGKTEDWKI"
     gene            complement(1990..>3053)
                     /locus_tag="TU257_002002"
     CDS             complement(1990..>3053)
                     /locus_tag="TU257_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0834964.1"
                     /translation="KDHTLNWFKSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTP
                     AEFCICLMLSLGIVIPLTQFTNYVNLLKSIEYAVKDINEILCIPNLISIDNNEHICTT
                     NIKFNNVFFSYDNENSVLENINIEIPQNSFTAIVGPSGSGKSTIIKLISRYWDVCGGE
                     ITIGGKNVKDISLNQLNDLIGYVSQNNFLFNESIMENIRMGNPDASDEEVIEVSKICA
                     CHDFIMELEEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAFIDPDNE
                     EKIQGAINVLTKNKTLIVVAHRLSTIKNADKIVVLKNKTIFDTGTHDELLEKCDLYKN
                     MWLSHIGAKSKSIVSNIGG"
BASE COUNT         1035 a          556 c          320 g         1142 t
ORIGIN      
        1 ttccagtaca atttacaatc acatcgcatt tagaacagaa tttgtctaat ttttctatgt
       61 tctctgcatc aaaaaatatg tattctatgt tatctttctt aataaaattc atatgacttc
      121 tcgatacagc ataaatataa ttatcttccc atttagacac tttttccata aaaagcgaac
      181 ctatattacc attgcaacct aaaactccta tattatacat aaacctcctc ctatctatat
      241 tatattttcc agtcctctgt tttacccctg attctcatat aatctctata cagaccatct
      301 tggctcatca gttctgtatg ctttcctatt tgagcaatct ctccttcttt caaaacaatt
      361 atctgatctg cttcttcaat tgttacaatt ctatgagcaa taataattac agtcttacct
      421 ttactcaaat tcgatattgc tctttgaatt aaatattcgt tttcaggatc tatgcttgat
      481 gttgcttcat ccaaaataat aattggagca tcttttagca ttgcccttgc tatagatatt
      541 ctttgttttt ctccaccaga taaaaaatca ccaccttcac caacaatagt ttcatatcca
      601 tttggcaaat tcattataaa ttcatgacaa tgtgacttct tcgctgcatt tattatttct
      661 tccttactta cattcggatt accaaatttt atattgtttt cgattgtatc attaaacaaa
      721 tacacctttt gaaatactgt acttatattt gaaagtaaac ttgataaagt caaatttttt
      781 atatttacat ttccaatttt tatactccca ccacttacat cataaaaacg agaaatgaga
      841 ttacaaattg ttgttttacc tgaccctgat ggtcctataa tagctgttac cgtattttcc
      901 tttatctcaa atgaaacatc ctttataatt gggattttat catatgcaaa tcttactttg
      961 tcaaaaacaa tattatgact actcaattcc atgtcttttc cattgtcatc caaaaaatca
     1021 gcatttttta tcttatctaa attatctaat gttttatcta aaatttccaa aacatgagtt
     1081 gcagaattta tattttccac tgatgaaaac ataatgaaag aaaatataaa tattgcaatc
     1141 ataatagaga tatctatttt attatttata gccatcattc cagctattat tacaatacac
     1201 attgatgcta attttaatga aaataaatgt aagcaattaa aaggtgtata ctctttttct
     1261 attctcaaat tcactttttt actacttaaa atagcagcat taaaattttt aagacttata
     1321 tcacccttgt taaaagcttt aacaatagga agtcctatta taagttccat tgtagattca
     1381 actaatttac tttgtgcatt aagataaaaa acagaatttt tctcagaatg tttacgaagt
     1441 aacaataaac aaaaatacga aagtactact ccagaaactg ctacaacacc caattcccaa
     1501 gataaaaaag aaatactgat tatcataaca agtgccatta tataaccgtt aataactatg
     1561 tctatcattt tcatcgaata attttcaaaa aaagacaaat ctgtggttac ggcagtagtc
     1621 aattctcccg gattattttc ttgaaaaaat cccaatggta ctctttttaa tatatcacca
     1681 atttgtactc gttcatcagc tgacatctca taaccaatac tatcctgatt tacagactta
     1741 aaataagcag ttatatatct ccctaaaacc aatccaatca ttatagtagt cactatggct
     1801 atttctttat ttccatatgt tgtactccca taatagtttc caagaacgag attaaaaaca
     1861 tatattgata gcattattgg cattgcaata aaaacagaat ttaagaaaga taatataaac
     1921 ccttttttta ttctcgtact atattttcta gaccaattta atattctgac agtcgtttta
     1981 aacattgcac taacctccta tattagatac gattgatttc gatttggctc ctatatgcga
     2041 taaccacata tttttatata aatcacattt ttcaagaagt tcatcgtgtg tacctgtatc
     2101 aaatatagtt ttatttttta aaaccacaat tttatctgcg ttttttatag ttgataatct
     2161 atgtgctaca actattaaag tcttattttt tgtcaaaaca ttaatagcac cttgtatttt
     2221 ttcttcatta tctggatcta taaatgctgt agcttcatca agcaatataa taggagcatt
     2281 tttcaacatc attctcgcta tagaaatcct ttgcctttgt ccacctgaaa gcttacttcc
     2341 aagacttccc acattggaat tatatccttc ttcaagttcc ataataaaat catggcaagc
     2401 gcaaatcttt gatacctcta taacttcttc gtcacttgca tcaggatttc ccatccgtat
     2461 attttccata atactttcat taaatagaaa gttattctgc gatacataac caattaaatc
     2521 attaagttga tttaatgata tatctttaac attttttcca cctattgtaa tttccccacc
     2581 acaaacatcc caatatcttg aaataagttt tattattgtg gattttcctg aacctgatgg
     2641 tccaactatt gcagtaaaag aattttgagg tatttctata tttatattct ctaggacact
     2701 attttcatta tcataagaga aaaaaacatt attaaacttt atatttgttg tacaaatatg
     2761 ttcattatta tcgatagaaa taagattagg aatacataga atctcattta tatcttttac
     2821 agcgtactct atacttttta acagattgac ataatttgta aattgagtga gaggaattac
     2881 tattccaaga gaaagcatta gacatatgca aaattcagca ggtgtcagtg ttccgtttaa
     2941 atatagaatc atacccacag gtaatgttcc caaaaatgtt gatggcaaaa tagaacttgc
     3001 aaaattcata atactccaag ttgatttaaa ccaattcaat gtatgatctt tgt
//
LOCUS       DARYJX010000087         2823 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYJX010000087 DARYJX010000000
VERSION     DARYJX010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2823
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..243
                     /locus_tag="TU257_002003"
     CDS             <1..243
                     /locus_tag="TU257_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL0834965.1"
                     /translation="PKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVNFDSEGYAN
                     GYYWISYVGGSGKRNYLAIGQTDKDGNRISLWGKLN"
     gene            396..917
                     /locus_tag="TU257_002004"
     CDS             396..917
                     /locus_tag="TU257_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0834966.1"
                     /translation="MHALFVANYIIEYSNKKGYPINNLKLQKLLYFVNVRNILENGAP
                     LFEESMEKWKYGPVVPDVYHEYKRFGAFSISTDEMIMEYVEFSHSPFADLEITEYNPE
                     NVENTGLIENTVAALNNRDPFELVNITHRHTPWKKDEDRIMEGIQGIKYTIEEIKDYF
                     GNHPEEKLWVQCH"
     gene            908..1717
                     /locus_tag="TU257_002005"
     CDS             908..1717
                     /locus_tag="TU257_002005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834967.1"
                     /translation="MPLKVIDSLLDGGLEDNSADPIKKSTLDVYYRYLLDSNLTIPYN
                     RIAKYVYENEQSDEVNEILENKIKFIVTKFQGGSKDKDILIKNLDKIKNNYMLAQVQK
                     EFIVENSKITRDGLKQIRKSTDNLEKQSNRMEKNVRVAEKELKQFKKTKSQIYTDFVT
                     ILGVFSSFVFIMFGGFSALSTMIGTLSTTEVSIGKTLVISSILLGFLLILIYSMLSWI
                     SIIIDKPIPLNCCSCNGNKLKHIGNTFLNNGYFFFLLIICVLCFMLGNYFK"
     gene            complement(1780..2766)
                     /locus_tag="TU257_002006"
     CDS             complement(1780..2766)
                     /locus_tag="TU257_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0834968.1"
                     /translation="MSKKLRNSLARIVVAAFASFAVMAIPTYHHSTVLAKTVSVNQTY
                     GEYKDYYTVIGESNIDQSAFPKIYKTTERVYKGQGTSEKRVTVSDVVYNPLDGYKRST
                     GAYGVVTKDMIDMSKGYREKWETNPEPSGWFRFYNRADNEEISEKEYDSRRTKSYKVT
                     NNVPVVLTTLKGKQYNSHLFVRSHLFADSLGGKSIRKNAITGTQMQNVGTRKGGMQYI
                     EKKVLSHITKNPDVYVFYSAIPEYQGTELLARSVLVSALSSDGVINETVRVFNTADGF
                     NINYEKGGLLTESPVSEIDNIEDSTTDEIENSVDDSEEIVYNDTTTEEEEEN"
BASE COUNT          931 a          443 c          497 g          952 t
ORIGIN      
        1 ccaaaaacag gtacttttac gctagatgtt gcagagatta acattagacg ttggccaagt
       61 ctcgccagcg aagtagtagg cagctataag caaggtgaca ccgttaactt tgacagcgag
      121 ggctacgcta atggctacta ctggattagc tatgtcggtg gctctggtaa gcgtaattac
      181 ctagcgattg gacagactga taaagatgga aaccgtatca gcctttgggg gaaattaaat
      241 taggaggtaa agctccgaga taagacaaat gccctcgctt ttgcgggggt atttttgtta
      301 tcaaaatcaa tatgtagtgt tagctaattt tttagctaac aagatatagt acttgacaaa
      361 tatgttataa ttaagaaaaa ggaggtgtaa ttgagatgca tgcattattt gttgcaaatt
      421 atataattga gtattcaaat aaaaaaggct acccaatcaa taatcttaaa ttgcaaaaat
      481 tattatactt cgtgaatgta agaaatattc ttgaaaatgg agctcctctt tttgaagaaa
      541 gtatggaaaa gtggaagtat ggaccagttg ttcctgatgt ctatcatgaa tataaacgtt
      601 ttggagcttt ttccatctct acagacgaga tgattatgga atatgttgaa ttcagccata
      661 gcccatttgc tgacctagaa ataaccgaat acaatccaga aaatgtcgag aatactggat
      721 tgattgagaa tacggtggct gccctaaata atcgtgatcc atttgaactt gttaatatta
      781 ctcatagaca cacaccttgg aaaaaggatg aggatagaat aatggaaggt attcaaggaa
      841 ttaaatatac tattgaagaa atcaaagatt attttggaaa tcatcccgag gagaaactat
      901 gggttcaatg ccattaaaag ttattgattc attgctggac ggtggcttgg aagataatag
      961 tgctgatcct attaaaaaat cgactttaga tgtttattat cgttatttac tcgattctaa
     1021 cttgactata ccttataata gaattgcaaa atatgtatat gaaaatgaac aaagcgatga
     1081 agttaatgag attttagaaa ataaaatcaa atttattgta actaaatttc aaggcggttc
     1141 aaaagataaa gatatcttaa taaaaaacct tgataaaata aaaaataact atatgcttgc
     1201 ccaagttcaa aaagaattta tagtggaaaa ctcaaaaatc accagagatg gattaaagca
     1261 aatacgaaaa tcaacagata atttagaaaa gcaatctaac agaatggaaa aaaatgtaag
     1321 agttgcggaa aaagaattaa aacagtttaa aaaaacaaaa tcacaaatat atactgattt
     1381 tgtaactatt ttgggtgtat tttcgtcgtt tgtctttatt atgtttggag gatttagtgc
     1441 tttgtcaact atgattggga ctctcagtac aactgaggta tcaattggta aaactttagt
     1501 catatcgtct attctattag gatttttgtt gattctaata tactctatgc ttagttggat
     1561 atctataatt attgataaac ccattccact aaactgttgt agttgtaatg gcaataagct
     1621 aaaacacata gggaatacat ttcttaacaa cggatatttt ttctttttat tgataatttg
     1681 tgtcttgtgc tttatgctag gtaactattt taaataaaaa aacaaccgct cagattaatt
     1741 tctgggcggt ttttgtgtgt ctaaaaattt tttgaaatct tagttttctt cttcttcttc
     1801 ggtagtagta tcgttataaa ctatttcttc tgaatcatcc acagaatttt ctatttcgtc
     1861 tgttgtagaa tcttcaatat tatcaatttc acttacaggg ctttctgtta agagtccacc
     1921 cttttcataa ttaatattaa atccatcagc ggtgttgaaa acacgaacag tttcattaat
     1981 tactccatcg gaagataaag cagatactaa aactgatctt gctaataact cagtcccctg
     2041 atattcaggg atggcgctgt agaatacata aacatcagga ttcttagtga tatggcttaa
     2101 aacttttttc tcaatatatt gcatcccacc tttacgtgtt cctacatttt gcatttgagt
     2161 tccagtaata gcgtttttcc gtatggactt tcctccaagg ctatcggcaa agagatggct
     2221 acgtacaaat aagtgactgt tgtattgttt accttttaat gttgttaaca ctacaggtac
     2281 attgttggta actttgtatg acttagtacg tcttgaatca tattctttct cactaatttc
     2341 ttcattatcg gctctattat aaaatctgaa ccaaccgctt ggttcgggat ttgtttccca
     2401 tttttcacgg tatcctttag acatgtcaat catatctttt gtgacaacgc cgtaagcgcc
     2461 tgttgaacgt ttatagccat ctaatgggtt ataaactaca tcagatacgg ttactctttt
     2521 ttcgcttgta ccttgtcctt tatagactct ctcggttgtt ttatatatct taggaaaagc
     2581 agattggtca atgtttgact caccaattac agtataatag tctttatatt caccataagt
     2641 ctgatttact gagactgttt tagctaagac tgtactgtga tgataagttg gaatcgccat
     2701 cacagcaaat gatgcgaatg ctgcaacaac tattctggcg agagagtttc taagcttttt
     2761 agacatatcc atgtcctcct ttaattattt acaggttaag tataccactt taaattaaaa
     2821 aaa
//
LOCUS       DARYJX010000088         2667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYJX010000088 DARYJX010000000
VERSION     DARYJX010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            11..1432
                     /locus_tag="TU257_002007"
     CDS             11..1432
                     /locus_tag="TU257_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL0834969.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLV
                     DRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNG
                     VADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEA
                     EDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQC
                     DGDIDMSVKNIVQAVKILNKEEF"
     gene            1433..1930
                     /locus_tag="TU257_002008"
     CDS             1433..1930
                     /locus_tag="TU257_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL0834970.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1954..2352)
                     /locus_tag="TU257_002009"
                     /pseudo
     CDS             complement(1954..2352)
                     /locus_tag="TU257_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2432..>2667
                     /locus_tag="TU257_002010"
     CDS             2432..>2667
                     /locus_tag="TU257_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0834971.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYISE"
BASE COUNT         1002 a          303 c          508 g          854 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcataaatta ttgtcgcagc tgcccatttc aactttttgg acaacaaatt atgataagtt
      361 aatagaaaaa gctttagaaa ataatatgaa aaagccttat gtaaaaacaa aggatgaaca
      421 attaagaggt acaaatcata attttgatgc gatagtatat aagctgcatg gtgatgtaga
      481 aactcccgaa gatgcagtaa taacaagaag tgattatgaa gagtttggat ataacaaaag
      541 aaaattattt agagaggttt tagaaggaga tttgcttact aaaacatttc tatttttggg
      601 atttagtttt gaagatccaa attttaacta tgtaattgga aggttaaggg tcttactcga
      661 tgaaaaaaat acaagaaaac attattgtat tatgaaaaga gtccaagatg ctgatgagga
      721 ttatgaatac aaaaaagcaa gacaggagct acaaattgaa gacctaaata gatatggtat
      781 ttttacatat ttagtaaata aatatgatga aatcaccgaa atattgagca ctcttgtcga
      841 tagatttaga aggaaaacaa tatttatatc tggtagtgcg tactcctatt cggcttattc
      901 tcagaaaact ggcgaaaatt ttattcataa actatctttt gaactatcaa aaaatggtta
      961 tcatattgtg aatggatatg gtaaaggagt cggtgaattt gtattaaatg gagttgcaga
     1021 ttattgtttg actcacaagt ccaaaataaa tgatttttta acacttatgc cttttcctca
     1081 aaatagttca ttaggtattg atttagataa gctatataaa gaaaatagag agcagatgat
     1141 tgaaagttgt ggtatagcta tatttctttt tggtaataag gaggcagaag atattgcaag
     1201 cggagttatg gacgaatatg agttatcaaa aaagcatgga ttagtatgtt tgcctattga
     1261 atatactggc ggtgcatcta aagaaatata tgatcaaaca actcaagaaa tttcagataa
     1321 aaatacaata agtgcaattg aacaggcaaa taaacaatgc gatggcgata ttgatatgtc
     1381 tgttaaaaac atagttcaag cagttaaaat attaaataag gaggaatttt aaatggcaaa
     1441 aagacaggta ttttttagct ttcattacga caatgataat tggagggcag gacaggttcg
     1501 caatatgggg aaagtagaca gtagttctac cttttctgat aatgactggg aggaagtaaa
     1561 agaaaaaact gaaagtaaaa ttaaagaatg gattgatgaa cagttaaata agcgttcatg
     1621 tttggttgtt ttgattggag aaaaaacagc gaacagaaaa tggataaatt atgaaataag
     1681 aaaagcatat gagttaaata aaggtattgt gggaatttat attcacaagt tggagaattc
     1741 actgggagag caagatgata agggtaataa tccttttgat tatttaacat tagaaggtga
     1801 aaaactttca aagtatgtta aatgttttga ctccaactat tcatcaagta aatatgttta
     1861 tagcgatatt aaagataata ttgaaggttt aattgagtat ggaataaacc ataaaccatc
     1921 aacttggtaa taaatgatga tggagagaaa aaattatctc tccatctcct tacccatgta
     1981 aattccataa ttttttcgta tcttgtaaag ttcgtccata atagattttg aggaagaata
     2041 ctcttgcata agggtattct ttttttcttg caatttatca agtctatcta aaataccctt
     2101 agaatttggc aacttggaat atgatttttt aagctctgaa agggcatttt catataaggt
     2161 aatctgagct ttgtactctt caaaaaatgc cttgtcagat ggacttgcct tatattcttt
     2221 gtagtattgc ctgtattttt taacagtgtg aacttgctcc atagtggcag aaagctcctg
     2281 catttcctta tcaatagcct tgatcttatc ctgtaaattt tgcctttcat cggctgcttt
     2341 tatgatatat ttcgattata ttcgaaaaca atattggaaa atatattttt atcgtgtata
     2401 atataatcaa agctaaagag aggtgaatga tatggaatat attgaacgac ccaagtattt
     2461 aaaccatata gaaaaatttg ttgataaacc tattattaaa atcttaactg ggatgcgaag
     2521 agttggaaaa tctaccattc tgatgatgat taaagatgaa attttgaaac atgtgccgga
     2581 tgagcaaaag atatatatca attttgaatc tttggagttt atgagtataa atgaagcgag
     2641 ctttttggca agttatataa gtgaaaa
//
LOCUS       DARYJX010000089         2581 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYJX010000089 DARYJX010000000
VERSION     DARYJX010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2581
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..116
                     /locus_tag="TU257_002011"
     CDS             <1..116
                     /locus_tag="TU257_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL0834972.1"
                     /translation="RTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            403..868
                     /gene="tnpA"
                     /locus_tag="TU257_002012"
                     /pseudo
     CDS             403..868
                     /gene="tnpA"
                     /locus_tag="TU257_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1050..1205)
                     /locus_tag="TU257_002013"
     CDS             complement(1050..1205)
                     /locus_tag="TU257_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0834973.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1299..2498)
                     /locus_tag="TU257_002014"
                     /pseudo
     CDS             complement(1299..2498)
                     /locus_tag="TU257_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
BASE COUNT          811 a          393 c          511 g          866 t
ORIGIN      
        1 aaaggacggt agcgaaatat attcgcgagc aggagaaaaa tgacattgca cttgataagt
       61 tgagtgttaa agaatatgaa gatccatttt cagatggcag ttttaaaaca agataaaagc
      121 ccgtttttac gggcattagt caagtaatca tagcactaac ctgaacgaag ttcagcgaac
      181 gtctttagac gtcgctggag agaaacggct tatagccggt gtacaagcca cccgttttta
      241 cgcgtggtta tgacttagtg actttagtcc gtttcgctcc gtaggtgcga aacaaaaatc
      301 ccccgctatg cgggtacgca tcgaacgtta tactacaaaa aaactccaaa cgcgctacaa
      361 tataggtgtt caagccaatt gtaaagcgaa aggagtaaaa atatggcaca aaagccccac
      421 agtttatcgc acacaaagta gcattgtaaa tatcacattg tgttcacccc taagtataga
      481 cgaaaagtaa tctataatca atatcgaggc agtttgggag aaatttttca aagattatgt
      541 agctataaag gtgtagaaat atatagaagg acatctgatg ccagatcacg tacacgtgtt
      601 agtaagcatt ccacccagaa taagtgtttc aagttttata ggatatttaa aaggtaagag
      661 tacgcttatg atgttcgaca agcacgccaa tctgaaatac aaatttggta atcgacactt
      721 ttgggcagaa ggctattata ttagtacggt tggattaaat gaagctacaa taaaaaaata
      781 tattcaagaa caagaaaaac atgacatagc actagataaa ctgagtgtaa aagaatatga
      841 ggatcccttt agagataagg gtaagtgata caaatacttc tttgagaggc aagtgacgag
      901 tcaatagcaa tgtggtttga acaaagtgaa agccagcgtc tttaggcgct ggctagttat
      961 atgggtttat agtccctatt caaaccacct gttggacggg tggttatgat ttctactaaa
     1021 aaaactatta ttacaatact aagtatatgt tagacaataa tattattaga acccacggag
     1081 gtatgtttat atttttgaga gcgattaaaa tttaatatct ctgaccacca atctccacct
     1141 gttatttgat tgagttcgga tgaatttagt tcttgaaatt gagtgagtga attttgtttt
     1201 tccatttgtg gacctccttc ttttttctaa tattataatt taagatcaat atattatttc
     1261 tctaaatcct aaatggtcat cgaaacgtcc ggaatggttt aatcatgatt tgacaacagt
     1321 ttattcttat aaaagtcgaa gtaggatttt ttagcgataa cacttgtaac acgaccctgt
     1381 gcaccatatt ttatcaagta gctatccttg gaagggagtt tggcaagagt tgtaatcttg
     1441 aaaagattac cttgttctgt ttttgttgct gttttatcaa tagtagaaat ttttccatta
     1501 acagtgatgg actgttttct cactttttga agatttagac gaacagtttg acctttttta
     1561 aggagagaaa cataatcaga agttacaaag tatgtaatca gagcttttct agtttgagta
     1621 atattaggat agattttggc aatatcacta ccatttggga taagactttt cccctcgtat
     1681 tcattattta gatgaataat cctggtttct ggtgctaaaa caacattagt gtctaactat
     1741 acacttgctt gttctagctg agctttaagt tcagtgattt gactgtcgat ggttgacagc
     1801 tgttgtgaag cattctgtag aaattgagtc ctcaagactt caactttggt ttctgaactg
     1861 ttatcgtatg ttgcactact accagtacct gctctttgaa tgctaagccc agagagggat
     1921 gattctaaac ctgaaatagt ctggttaatc tgagagataa actggttaga cgtggaagtt
     1981 tattcttctt gtgattgaga cagataatta ttgagaatat cttgatgagg attaccagtt
     2041 ggtaagattg tgttatgatt tgagatagct tgacgaagat cttcatattc tgaaatctgc
     2101 tggtttatag tattgatttg agtatcaatt gcagcaaggg tgttatttgc aagtgtggat
     2161 tgattggata cttctgtatt tattttagcg ataccaagtt taatctcttg agactgattt
     2221 ataaagttgt tgaaggtgtc agcaagacca aattcatcat tttgtggtaa gaggttcgtt
     2281 ccttgtttga gactttcttt caatgtctct aaaccaactt tttgtttatt caacgtattt
     2341 aattgtgatt ctagagaatt cttttgagaa ctctcaatgg tttctttata tttgattaaa
     2401 cgttttcctt ttttaacgag ttggttttct ttaagattat ttttaacgat agcattgttg
     2461 ctagttgact gtattgatgc aatgactttt gtaggcataa tttcacctcg tgacgatacc
     2521 gttacttctt tttgaccaag aaaagaaaat gaaagtaaaa atatgacgaa taatgttaat
     2581 g
//
LOCUS       DARYJX010000090         2473 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYJX010000090 DARYJX010000000
VERSION     DARYJX010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            51..1004
                     /locus_tag="TU257_002015"
     CDS             51..1004
                     /locus_tag="TU257_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0834974.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1064..2263
                     /locus_tag="TU257_002016"
     CDS             1064..2263
                     /locus_tag="TU257_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0834975.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          746 t
ORIGIN      
        1 tggctagtgg tattcttttc atttcagcct tattttgata tgatagacgt atgaattttg
       61 aaaagattga acaagcctat gagcttatat tagaaaatag ccagctgatt gaaaatgatt
      121 taaaaacgca tatctatgat gctattgttg agcagaattc tttttatctg ggagcccaag
      181 gagcaagccc tcaggttgct aaaaatattg agacgttgaa ggccttgcag ttaaccaagg
      241 aggagtggcg ccaggcttat cagtttgttt tgatcaaggc tgggaaaaca gagccattac
      301 aggccaacca ccaatttacc ccagacgcga tcggctttat catgctttat attttggaga
      361 ccttgagctc acaagagtca cttgatgtgc ttgagattgg cagtggaaca ggtaatttag
      421 ctcaaactat tttaaaccac tcacataaga gcattgatta tttaggcatt gagcttgatg
      481 atttactaat tgatctatca gctagtatcg ctgaaatcat ggggtcatca gcccagttta
      541 ttcaagagga tgctatcaga cctcagctgt taaaagaaag tgatctcatc attagcgatt
      601 tgccagttgg tttttatcct aacgacgata ttgctagcag gtatcaggtg gctagctcag
      661 atgagcatac ctatgcccat catttactga tggagcaagc cttaaagtac ctgaaaaaag
      721 atggctttgc tattttctta gcaccggtaa atcttttgag cagcccacaa agtcacctct
      781 taaaacaatg gctgaagggc tatgctcagg ttgtggcctt gattactttg cctgaggctg
      841 tgtttggaaa tccagctaat gcaaaatcga ttattgttct ttgtaagcaa tcgaatcgct
      901 ttgcagaaac ctttgtttac cccattaggg atttgaaatc tgttgataat gttcgtgatt
      961 ttatggaaaa cttcaaaaat tggaaacggg ataatgttat ttaagagaat tttttgatat
     1021 aatagaaaag cattgcagaa aacgatttca agagaggtaa aacatgtcaa agacaattgc
     1081 aattaatgca ggaagctcca gcttaaaatg gcagctatat caaatgccag aggaaaaggt
     1141 attagcacag ggaattatcg aacgtatcgg tctgacagac tcaatctcta ctgttaaata
     1201 cgatggcaaa aaagaagagc atattcttga tattccagat catacagagg ctgttaagcg
     1261 cttgttgaat gatttgattc attttggcat tattggtacg tatgacgaga tcacaggtgt
     1321 tgggcaccgt attgttgcag gtggtgaata cttcaaggaa tctgtggttg ttgatgataa
     1381 ggttgttgag caggttgagg agttagcagc cttggcaccc ttgcacaatc cgggggcagc
     1441 agcaggtatt cgtgcctttc gtaagatttt gccggacatt acgagtgttt gtgtgtttga
     1501 tacttcgttt cataccacaa tgcaaaagca tacctacctt tatccaattc ctcaaaaata
     1561 ttatacagat tataaggttc gcaagtacgg ggcgcatggg actagccata aatatgttgc
     1621 tgaggaagca gcaaaaatgc tgggtcgccc tctagacgaa ttaaagctca ttacagccca
     1681 tgttggtaat ggtgtgtcta tcacagccaa ttatcatggt cagtcagtgg atacctctat
     1741 gggctttaca ccgcttgctg gtccgatgat ggggacacgc tctggtgata ttgatcctgc
     1801 tattattcct tatttgattg ctcaggatcc tgagctaaag gacgcagcag atgtggtcaa
     1861 tatgcttaac aagcaatctg gattaggtgg tgtgtctggt atttccagtg atatgcgtga
     1921 tattgaggct ggcttgcagg ctaacaatcc agatgccgtc ttagcttaca atatctttat
     1981 cgatcgtatc aagaaattta tcggacaata ctttgcggta ttaaatggtg cagatgcctt
     2041 ggtctttacc gcaggtatgg gtgagaatgc tcccttgatg cgccaagatg tcgtcaatgg
     2101 cttgtcatgg tttggtatgg aaattgatcc agagaaaaat gtgtttggtt atcgtggtga
     2161 tatttcaaca gcagcttcaa aggtgaaggt gcttgtcatc tcaactgatg aagagctgtg
     2221 tattgcgcgt gacgttgaac gcttgaaaca gactatatca taatctgata atatactctt
     2281 agctcagctg atcagtttta aagagtccaa aaaatacttt taattggtac cgacctccaa
     2341 aagttagact taaaggttta acgattggag gtcggtatta ttatatagcc aaatattctc
     2401 aagacaaaga cagccaaaaa atgagacggt cgtaaccgtc tcaaaaaagt ttaatttaat
     2461 taaaaacatt cat
//
LOCUS       DARYJX010000091         2357 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYJX010000091 DARYJX010000000
VERSION     DARYJX010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..858)
                     /locus_tag="TU257_002017"
     CDS             complement(<1..858)
                     /locus_tag="TU257_002017"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834976.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPVETEGVYILSDRNYKDSNVIFYR
                     YGLIEPREKVFVNAVPILIGPNGEQWQDFQKCYFDLPHWIEDLQEKQILLSSYLSENY
                     QVESLLKQSNGGNIYKAIHLDTGKNVVIKECRSHIICTASISKKQLRDNEWNLSGLIT
                     NNIPKSIEKV"
     gene            complement(1274..2140)
                     /locus_tag="TU257_002018"
     CDS             complement(1274..2140)
                     /locus_tag="TU257_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL0834977.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          744 a          448 c          317 g          848 t
ORIGIN      
        1 aactttttca atactttttg ggatattatt agttattaga ccagatagat tccattcgtt
       61 atctctcaac tgttttttac taatactagc tgtacagata atatgagagc gacattcttt
      121 gataactaca ttttttccag tatctagatg aatagcttta taaatatttc caccattaga
      181 ttgctttagt aagctttcca cttgataatt ttcacttaaa tatgacgaca ataaaatctg
      241 tttttcttgt aaatcttcaa tccaatgagg taaatcaaaa taacacttct ggaaatcctg
      301 ccattgctct ccgtttggtc caattaatat tggaactgca tttacaaaaa ctttttctct
      361 aggttcaata agtccatacc tataaaaaat aacatttgaa tctttatagt ttctatcact
      421 aagtatatag actccttctg tctcaacagg tatcaattca tacaagtcac ttaataattg
      481 tttacagtgt tctctatctc tgggataaat tgtgatgaat ttcccagatt ccgaaggatc
      541 ttccatatcg gatacatttt ctaaaatcat tttttcgtct tttaaatatt taaaagaaat
      601 atgatgacat tttaaatacg gaaatactac agaaaaaatt gctttatagt tttgaaatgt
      661 tcctgaaata tgaattttaa atccatattc aggtaaaaca taatcattcg tctctacata
      721 tctaaagctt gtcagatcca tatgcttcac catgtaccag ctgaataaat gggtacttct
      781 ctggatgctc catgattgtc ttaactttct tttccacgta ggcttcaaag cttttttcaa
      841 agctacttga acactcacga gaatcttctt tatagataca tttttaagta atcattggtt
      901 ttctcatagc aatacatctc ctcagtctta ttagtataaa actaaaaacg ctcacattaa
      961 caggtctttt tgagcgtttt tagtaggact agttactaaa ttatggtttg tagattggac
     1021 atttccaagt cacaacaaag cctttcactg gcgcaaagca tctactagcc tcgtatgcaa
     1081 attgagtcat gtttgtgatc tcctttcatt cttgatgagt ctagtgtatc atcaaaaacc
     1141 gtaccaaagc taaactgttc atatgttcaa atcatggttt tgacattaat caaaaaacag
     1201 tagctcaaaa agccactgtt tgctactagc taagcatcta aaccattttg cttatcaatg
     1261 ctttaagttg catttattca acttccttta accatttctc taaactatct gaataatagg
     1321 ctgcactttc atcacaattt aatgccttta agatgtgtat ggcgtcattt atttgcttta
     1381 agcctagttc cttttcccct ttacaatata ggtgctgacc atcagcaatc atataaacaa
     1441 ttcttaagta ggtgtcattt tcttcaaaaa aatgattgtt aatcatttta tcaaaatatg
     1501 cagctatacc tagccttttt tcctgagtag ctttaaacag cccatttaat aaaatgctgt
     1561 gcactaaatt tcgatgctgc caaagctcct caaaaaagtc tactcttcct agcatttctc
     1621 gagtataccg caaatacaca tccaaggata ataagggaga aatatctgaa aataattgta
     1681 attcgtatat tccccaaatc tccactgaaa acaaataatc atataaaaag ctttgctcat
     1741 ctggagtcat tttgatattc tcgtctaaaa agagcatttg gcttttaatc atcaaagcat
     1801 ttaaaaaata gatatccttt ttgtataaat gatactgctc cagctctttt gtatacaatt
     1861 gatgtaagct ggacaggtct ttttttgata tggcctccca gatctcttgc tttaggacag
     1921 catatgggga aggcttaaag ccatttgcta gatagataaa ttcattgagc tctgtccgaa
     1981 tattgctaag tccaaccaat agctttgaga ttgttatatc ggattcacca ttttcaaatc
     2041 tgcttaacat cgagtgagaa aagtcatctc ccgtcgcttc ctttaacgat atgtgtcgcg
     2101 atgtccgcag taatttaaac atttctccca tatattgcat atcaatacct cttcaatctt
     2161 tcattttagt atagtatata accttaaaaa tgtaaatcca gtcttgattg cataaacctt
     2221 taattcaacg tttgatgcta ctaaatatcc tatttttctg aagtagatcc tcatctttat
     2281 gctataagca cttgctgcgt tttagaaaat gggctaaatc agctatactc ctttttaata
     2341 acaaaaaagc cttattt
//
LOCUS       DARYJX010000092         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYJX010000092 DARYJX010000000
VERSION     DARYJX010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU257_002019"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU257_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL0834978.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU257_002020"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU257_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL0834979.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          557 c          389 g          644 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagc caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYJX010000093         2151 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYJX010000093 DARYJX010000000
VERSION     DARYJX010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            146..547
                     /locus_tag="TU257_002021"
     CDS             146..547
                     /locus_tag="TU257_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0834980.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            1003..1170
                     /locus_tag="TU257_002022"
     CDS             1003..1170
                     /locus_tag="TU257_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0834981.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1269..>2151
                     /locus_tag="TU257_002023"
     CDS             1269..>2151
                     /locus_tag="TU257_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0834982.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          875 a          234 c          411 g          631 t
ORIGIN      
        1 tttttctagt attagaatat agaacaaata agactttata ttttcatttt tattttagag
       61 gatcttgcac gtcaaaatgc agaggtcctc cttttttatt caaaaaataa gtttgaaatt
      121 tttgataaaa aggagggctt tacaaatggc agttaaaaga aaatatatct atgtaaaagg
      181 tcaaaagatt tatgtacctg acgaagtgta tagagcatat aaaaaagggc ttaatcatga
      241 aactcattta aagagattgg atagaaagca tggcgtattt cgttttggag actttaacac
      301 aagtattgta gatattgcag ataatactgt tgatgttgaa aaaatcattg aaacaaaaat
      361 gctgatagaa gatctgtatt atgcattaga cagtttaaat gatgaagaga gaaaactaat
      421 tgaagcacta tattttgatg ataaaactct cacagaagtt gcaaaacaaa gagacacaaa
      481 tccaatgaaa atcagtagat taagaaataa gattttagaa aagctgagaa aatttttgga
      541 taagtaaatt aagtagaggg cagggaaaca tctctgtcct ctatttttga aaatttttca
      601 aaaatagtgt taaaagttgt cctgaaagta aggtttatat atagagggac ttttattacc
      661 tcgttatata tagatttgat ctttgacaac tgaatagacc aagacaagac tttaaccagt
      721 agtggagcaa tttataaact tacgccaaga taaacctgct aagttaaatt gatttaaatg
      781 aatacctaca tttgtagagg atataaggtt tggagcgata aataagtctg tataaaaaga
      841 gggtggcaac tcttgtgcga tgatactaat ggggataatg atacttctac agttgaagcc
      901 ggctcatctt gaaaagaggc ggaggtgaaa ttcctatgta gcagccaatg cacttgtcaa
      961 tgtcataaaa cttaaaaata ttgaagataa ggagaagata ttatgtgtga agaacataat
     1021 atagatatta agatggaaat agataaaaaa gataaacaga caataaatca aattgatggt
     1081 tggaatatcg aagttaaatt taatgaaaat ggattgagct tagaaaattt agtagaggaa
     1141 tacatcaaag aaaaattttc tgtctattag gggctgacaa aaaatataag gagcgttata
     1201 atatttttgt ggaagcctaa ccttggttcg atttattgta tgtaaattga atttaaggag
     1261 gcttttttat gtttaaagac agtgtaaata aagaaaatat tgcagttatg tatttgaggc
     1321 tttcaaaaga agatggagaa aaaacagaaa gtaattctat atccaaccaa agagagatga
     1381 taaattctta cgcaaagaaa aatcaattta taattatcaa agagtatgtt gatgacggat
     1441 attcaggagc aacttttgat cgtcctaatt ttaaagaaat gataaatgat gcttatgata
     1501 agaaatttga tacgattatt gtaaaagacc tatcaagatt tggaagagat tatatagaag
     1561 cagggaaata tatacaaaga atatttccgg aaaacgggat aagatttata tctgtaaatg
     1621 acaactatga tagtaaaagt gcggatatga atgatacaca tctaatactc cctataaaaa
     1681 actttatcaa cgacagctat tgccgagata tttccaataa agtaaagagt tctcagaaga
     1741 taaaaagaga aaaaggggat tttatcagtg cttttgcacc ttatggatat aaaaaatctg
     1801 atgagaataa aaataagttg gtggttgatg aacaagctgc tcctaacatc aaaaatatat
     1861 ttgatatgaa gctcttggga tattcctcaa aggcaatcgc agatgaatta aatcacttag
     1921 gtgttttgac tccgaggaaa tataaagaaa gtcaaggctt taagtgtaat ggatttcaaa
     1981 atataaaagg tggtaattgg tcagcaaagt cagtaaacag aattatagaa aatgaagtat
     2041 atattgggaa caccttgcaa ggcaaaagtg ttaccttaaa ctataaaaat aaaaaacaga
     2101 tagaaagaga gaaagaagat tggataagag tagaaaatac tcatgatgca a
//
LOCUS       DARYJX010000094         2150 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYJX010000094 DARYJX010000000
VERSION     DARYJX010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2150
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            67..260
                     /gene="ssrS"
                     /locus_tag="TU257_002024"
     ncRNA           67..260
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TU257_002024"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            262..334
                     /locus_tag="TU257_002025"
     tRNA            262..334
                     /locus_tag="TU257_002025"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Lys,seq:ctt)
     gene            560..1054
                     /locus_tag="TU257_002026"
                     /pseudo
     CDS             560..1054
                     /locus_tag="TU257_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1418..2128)
                     /gene="speh"
                     /locus_tag="TU257_002027"
     CDS             complement(1418..2128)
                     /gene="speh"
                     /locus_tag="TU257_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL0834983.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
BASE COUNT          741 a          361 c          327 g          721 t
ORIGIN      
        1 atacgatctt tttttcattt tagggcttga aaaattttca aaaagtggta tcataagagc
       61 atagagttat tgctgtggca tacgaattca catctaagtg ttgaccgact atttttttgt
      121 attttaggga aacaaagtct atctctagta tgcaagccgt ttcacgtgga agcaatctga
      181 agagaagtat gttgcccacc tgcttatatc gtgcgggttc aatacaaaac gtgaatcacc
      241 ggtgccaata cagctttcct tacctcctta gctcagttgg tagagcagta gactcttaat
      301 ctatgggtca caggttcgag ccctgtaggg ggtatagtgt aaaaacgaca aaaagccttt
      361 attgcagggc ttttttgctt gcctaaagag ggtttgtccc accatttgtc cccgaaacaa
      421 ttttttatga tatgatgtta aataaagaat ttattacttt ttaaaaagag agctaacaca
      481 tgacaataat ataattaaca caaggtgata caatcggagt attttcacct ccatcacctg
      541 cgacggaatt tggagaaaaa tggctttttt taattattcg caggctttaa cagttggaca
      601 aatagatatt aaaaatgctc gcttaaaagc tggaaaaaca caaaaagaac tcgctaaatt
      661 aataggagtt actaagcaaa caattattaa tgacgaaaag gggactactg aaccttcatg
      721 ggataggctt caagagattg ctacagcctt aaatgttgat attgatacct tatttcccta
      781 caatatgtta ggagaaaaaa gagactttaa gtggatggag cacctagaga gactcgaaaa
      841 taattggctt tatagccgta tggccgagga agaagtatta cttcaaaaaa ttctagattt
      901 tgcaatattt caaaataaat tagataaaaa cactctaaca actaaagaac ttaatcttga
      961 agacaacaac actatgtcca aagaagataa aatttcactc atcatattga aatatgaaaa
     1021 agaaattcaa gaaaaaactc aaaaacttct tgagtttatt cccgaaaaaa cacaaggaac
     1081 aataatggtt acaaagtcga taataaaagc atttgttagt attaaaccgg tattgtatcg
     1141 acacaagaaa cgacaaaagt tctaaactta tgccccaatt ttgccccaat ggttctttct
     1201 tgattctttg gtgaactaaa attattcaga ctcagaaagt tctgccataa catcggatat
     1261 ccgctcgatt gtcacaacct cccaatctct tatctcctca tatattttat attaaaatat
     1321 caataaatat tagcataatt ttaaaacact aaaaatatat cttggtaatt tttactttat
     1381 ttatctattt ttaataaaca gcttcttaaa aatataatta gctgattgac acatctacat
     1441 gaaattgagt tgagtctatt ctctcgttat tggaatatat ttttagcatg ctattaaagt
     1501 ctccattgcc aaaataatac aaatcaaaaa caatatcttt acctgaattt aaatctaagg
     1561 taacagttcc tttagagtat ttttgttccc ggttattata gatatcgtat ttcttaatca
     1621 ataactttct aacttttata tccacttcct gagcggttac tttcggttta ttgactgtaa
     1681 taaacatagg cggatgttgt ttacttttat cccacacgtt tataggaact ttaatttctt
     1741 ttttttctga attagttaat gtaattccac caaacgcttc ataccttttt cctggacatt
     1801 cacaagcctc ttgtgcagat agagcataaa tatctacttc tttatctttg aattcctgtg
     1861 atatccaatc tttctcaaaa aaaactgaca aatttttatc cttgacacta tatttcaaca
     1921 tatggcttgt tacaatatct ggagaatttt ttatactatc ggcttcaatt aagttagaat
     1981 catgcttata aagcgattct agattatgtc tattggttgt attataagaa tttgcttgaa
     2041 caacattgga atataaaaga aatgacaaac atataatcat gctgtagatt ttcttatcaa
     2101 tatgtgagta gcgacaatta tatctcattt tttctcctta agaagtgaga
//
LOCUS       DARYJX010000095         1917 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYJX010000095 DARYJX010000000
VERSION     DARYJX010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1917
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1090)
                     /locus_tag="TU257_002028"
     CDS             complement(<1..1090)
                     /locus_tag="TU257_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL0834984.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKSIYSVIENKNTIS"
     gene            complement(1090..1458)
                     /locus_tag="TU257_002029"
     CDS             complement(1090..1458)
                     /locus_tag="TU257_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL0834985.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
BASE COUNT          559 a          314 c          283 g          761 t
ORIGIN      
        1 cagaaatcgt atttttattt tctattacag aataaatgga cttcatttct ttttctattt
       61 gctttatatg atccaataat tgttgtctat ctgatgccac tttctttaat tttaaatcta
      121 attcctcgta ggagttaata cctgattttc tcatttcatt taaggcagat gccatagttt
      181 tcatattatg tttacctgcc catacttcat atcccttaga tgattttacc ttttcattgt
      241 ttttcatatc tacaatagta tccggtttct tgtaggagcg tttttcataa tgatattcct
      301 gattaacata aatattttgc ttatttgaat cttcgattcg ttccttgatt ctctcttttg
      361 tataatcttc ccctaaagta gatgctttcg ctctggtaaa tcttccctta tctcttttat
      421 ctttatgtcg gaaggaaagg tattttccta ttttgatttc ataaccgaaa tcctccattg
      481 tctttagaaa ttcctcgtaa gttttggatt ttaaaacagc tttatcaata gtaagttgta
      541 gtttattctt ccaagagttt cctttcttaa attcggtata ttccatatag gttttaccat
      601 ttgtagagta tctgttttta aattttttgt agttttcatc aataactgac aagccatttt
      661 ctctacataa atcatcactg accgttcgga tttgatgata acttctctta ttactttgat
      721 atgcctttcc tgtttcaaag ctgacattgt taaacagaat atgattgtgt agatgcccct
      781 tgtcgatatg tgttgtaagg acatattcat actttcccct caagactctc tcacatagat
      841 ccagtccgat ttggtgtgcc tgctcaggtg tagtttctcc tggagcgaag gcttgaatta
      901 gatgccttgc caagattttt gctttggaat tacattcttt ttttgtatgt tcaaattcaa
      961 gatgggctgt tttgggattg cagccaaaag aggagataag gattttttca tcggttttat
     1021 cttcattcat aatatagtct aatgctagat aaagtgtttt ttctatcgga tgaatttttg
     1081 taactgccat tagatttcct ccgtaccact tgttccaaaa ttccctaatt catatagctt
     1141 tttacgaaga aagtagatgt cttttccttg tttttccaag agctttttca aatcattgat
     1201 gtcatctttg taaattacag cagttgaatt tacccttttt gcaatctgat tgatgctacc
     1261 tgtaatcctt ccgatatttg tagacatctc cttaaacact ttcatatcca gtacaaaaat
     1321 atctttttca aggatgcact tcataataaa ctgtcttaaa cttttacaac cggacagttc
     1381 atatttttta ttcaaaattt caagttcatc atcagaaagc ataaggtata ttccattatt
     1441 tcttgttctg tttgccatag tataacctcc aattcataga tgtattaaaa gtttacaaaa
     1501 gaaaaaacct gtaaaatcaa gtacaaactt gatatacagg tttcattttt atatttcttt
     1561 gtcaagaaat ctcctgttaa gagataaaat tcttatttaa atttcaagag tattatatca
     1621 tttgttggag aaaaattcaa tgaaagagag gtaatatacg gataaattta tggaaaaatt
     1681 taagataata attacaaata agattgattt cacaggggtt tggggattcc cccaacaagc
     1741 taaaattgag gaaaatagtc cgatgcaaaa gcaagggcta tgtcaatttt tttcgtaagt
     1801 gcatatgcat ttactgtgct tgctcaaaaa gaaaaaaaca tatataatga attagcgaat
     1861 atatggtatg aagtattcgg aatttttatg tttatgattg gttatgataa aatttgg
//
LOCUS       DARYJX010000096         1917 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYJX010000096 DARYJX010000000
VERSION     DARYJX010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1917
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            34..465
                     /locus_tag="TU257_002030"
     CDS             34..465
                     /locus_tag="TU257_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834986.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            680..1093
                     /locus_tag="TU257_002031"
     CDS             680..1093
                     /locus_tag="TU257_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834987.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            1077..1331
                     /locus_tag="TU257_002032"
     CDS             1077..1331
                     /locus_tag="TU257_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834988.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            1350..1748
                     /locus_tag="TU257_002033"
     CDS             1350..1748
                     /locus_tag="TU257_002033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834989.1"
                     /translation="MKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQER
                     AAIYFSNTYENIHKIKIIGIDKNLKTGSMNKATIVNSKYYISVTFMGGEIYTGVEQAS
                     KDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            1751..>1917
                     /locus_tag="TU257_002034"
     CDS             1751..>1917
                     /locus_tag="TU257_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0834990.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVV"
BASE COUNT          765 a          227 c          376 g          549 t
ORIGIN      
        1 ccaccttatg ataaagcata aaggaatata agcatgatag tctacctaaa gcaacacaaa
       61 aattactgga aattagtcag catagcagct ttaatcatta ttttaggagg aatactaaca
      121 atgaattggc ttaatgggga tagggacaat aaaggcgaga ataactacta tcaagtagag
      181 aaggatttag caatggaaat tgttagtgag tttgaaggag taaaagagat tagctttctt
      241 agtccagtac aatccaaaga aacagggtat tggggaacaa cagctactat aaataaaact
      301 aatgagatat cttattcttt ttcgatgact ttttcaggaa agcttgatga ttattcttac
      361 tattacgata aatgttttaa attagtgaag cgtcacaaaa aattgacatt aagtcaagtg
      421 gatctaacag atattgatat taaatattct aagggaggga aataaatgat aactgacaaa
      481 aactataact ggctagctgg aaaagtatat gatgttgatg ctaataaagt aactattcct
      541 gttagaaaaa atacggatat tcttaatcgt tatgtcaaag tccttgaagc cgaagacaat
      601 cctgacaacg gtatgcagtt tacggtgtca aagagtaata ggaatgttct agctttaaat
      661 tataaactaa ggagcttcta tgacagtaaa aaagaaagtc atcattttat taggaatggt
      721 agcaatttta gtaatgggag gtatatttat gtttagctat aatcagaatc aagcgaaaat
      781 gttagaacga caatttaacc atgaacaaaa acgaattgtc ttgtatttgt taaatcatta
      841 tagcggaatt aatgagatag aatttaatga tattgaaaac aacagtacaa caggttctaa
      901 gaatgtattg ctgacaataa ataataaaat taaaatggaa gttacatttt ttaatttaaa
      961 tgatgataca gataactatg ttattagttg gaatgggaaa ttaagtttga tagacaaaaa
     1021 tcctataact catttaagtt caatagataa aataaaagta aaatattgga gtaacaatga
     1081 tagtaacaga taaaaattat aatgatatag ccgatggggt ttataaggtt gatgctggca
     1141 aagttattag accttggcga aacggtaaga cttttaaaac taacgggaaa gattaccgcg
     1201 tcctcaaaac agaagacaac cccgacaatg gtatgcaggc tattgctgta gctccgatta
     1261 agggtagtga ggtgggtaag agtcatatca tgattgttta tgtaaaaagc agctattggc
     1321 tagcgtccta gcaataaaag gagttgatga tgaaaaagca acaaagcaaa cgacggaaac
     1381 taattggcat agtggcttta ataacaattt taggaggaat actaacaatg aattggttta
     1441 atgacgaaaa actaaataga gagcgtagag aacaagagag ggcagctatt tattttagta
     1501 atacatatga aaatatacat aaaataaaga tcatcggtat agataaaaat ttaaaaacag
     1561 gttctatgaa taaagctaca attgttaata gtaagtacta tatatccgta acgtttatgg
     1621 gaggtgagat ttatacaggt gtagagcaag cttcaaaaga caatgaggaa tttttaaatc
     1681 gtcgaaaaaa agcagagaat aagacaacct tgagtaagga cattgaagtt atttataagg
     1741 agaaatagta gtggttagtg ataaagatta taataaactc tctgaaaaag tatatgatgt
     1801 tgatgctaat aaagtaacta tttctgttag aaaaaatacg gatattctta atcgttatgt
     1861 caaaatcctc aaagccgaag atacccccga caatggtatg caagctatgg ctgttgt
//
LOCUS       DARYJX010000097         1658 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYJX010000097 DARYJX010000000
VERSION     DARYJX010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1658
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..327
                     /locus_tag="TU257_002035"
     CDS             <1..327
                     /locus_tag="TU257_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834991.1"
                     /translation="GGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFK
                     QNSQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILN
                     FVELYK"
     gene            337..>1658
                     /locus_tag="TU257_002036"
     CDS             337..>1658
                     /locus_tag="TU257_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834992.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPEQWREDLEKQISEAIEKAKKAQEEINQRTD"
BASE COUNT          553 a          268 c          384 g          453 t
ORIGIN      
        1 gggggcagtt ttgcctatgc aggaaccgct aaagcaagtc agctagagtg gccttttatt
       61 atagagctta ctccttctgg aggtcagact aatttttata ttgaaattga tggcaggcgc
      121 tttgagttta agcagaatag ccagctacaa aatagtgata aattactttt gacaggcata
      181 gctaccacac taaacggaaa ttatgtcaat gctaaaacga actatgagta ttttatcttc
      241 aatcctaatc ctaacaagag aattacttac aaaacggatt ttcttggcac gattaggatt
      301 ttaaattttg tagagttgta taaataggga ggtctaatga ttactttttt ggatcatcgt
      361 gacattgagt atggggtcat tagtgtcatt aggcatacta atgctgttaa tggtgagcgc
      421 tcagtgagcg gggaaattta tacaaacagt gatgtcctca ataatatcga tagagggtgg
      481 cgacttagat ttgaagatga gtattacgtt gttatttacg caaagcctgt tgatgttggt
      541 caaaaaacgc aagtttcgtt tgatgccata caccaatttt tttgggactt cagcaagagt
      601 agtatctatg agggtctcgg agatgggtct cataccattg atacctatct agagacagta
      661 tttaaaggta gtgggtaccg ctataagcta gaagtaggtg tgaacgcatt tagaaaacaa
      721 tcttttaatt ataagtctag gttagattta ttcaatgaga ttattaaagc gaccggactt
      781 gagttttcag tcagcgggaa agttgttcgg ctattaaaaa acataggtac tgatctgtca
      841 acagtggtac gaaaaaattt caacatgaat gatcttacca ttgaaaaaaa tattgatagc
      901 tttattacct atcagaaagg ctttggtgca tggaccgacc cagaggacca ctctaagggg
      961 agacttgagg cggaatacga aagccctctt gccaaggagt acggtcgact tgaaggggcg
     1021 cctctgacgg atgagcgctt cacggtggca gataatctaa aagaagcttt aaaaagtaat
     1081 gttgaaaatt cttataagat atcagtaaaa attgatatgg aagatttaac gagagctggt
     1141 tatagatgtg agaggccggt tgctggtgac tacattatgg cgataaatga gactttaggt
     1201 tttcaagagc gtatacggat agtttctttt acaagctact acgacgcaac tggagcttta
     1261 gtaaaacatg aagtcacttg taatgatatc ggatctgtga aaaaacaaag cgtaggaagt
     1321 ctgtctataa acagtagaat caatcagata gatgcagata ttgcttctgc aattgaagta
     1381 gcaacacaag cactagtgtc tgctgacggg aaaaatactg tttacggtgg cacagaaatg
     1441 cccaaagatg aaccaaaagg aaccttaaaa aaaggagaca tactattcct aaaagttggc
     1501 gatactacta gaatgtattt ctggaatggt gctgagtggg aagaacccga ggttgtgaac
     1561 gacccagaac aatggcgtga agacctcgaa aaacaaatct ctgaggcaat cgaaaaagcc
     1621 aaaaaagcgc aagaagaaat caaccagcgc accgacaa
//
LOCUS       DARYJX010000098         1618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYJX010000098 DARYJX010000000
VERSION     DARYJX010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..494)
                     /locus_tag="TU257_002037"
     CDS             complement(<1..494)
                     /locus_tag="TU257_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834993.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGET"
     gene            complement(506..>1618)
                     /locus_tag="TU257_002038"
     CDS             complement(506..>1618)
                     /locus_tag="TU257_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834994.1"
                     /translation="TQMANNVNAQTGTMSLQGLNDSMSLASGISANMSVANINATTQA
                     QEMASGVNGATSSMNLDAINHTLSLASGVGANMGTASTSATSQAQAMSSGVSNSLASM
                     QSNSTKAASGLSNSVTSEMSSAATSATSSANRLSSAVESGFNKAKTSATTSMNGIANA
                     VKTGFSSINSTAKQSMANLVSAVASGMSRATAVSNNACQKILSIFRALAGQMSSAGAY
                     AGQGFANGLASSAGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALG
                     MAEWIGEINSLGKAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLS
                     EPIFEVHNEIVGDKIYTAVKEKESREQSKDSYFVFD"
BASE COUNT          436 a          374 c          315 g          493 t
ORIGIN      
        1 tttgtctcac cgaaaggtaa ttcagcagtt cttagcgcga aggaaagatt atattttagt
       61 ccttgactgg tttttcctat aaattcataa gcgatagtgt cgtctaagat gactttaaat
      121 ctatatttcc aaggtttatg aggagagcca ataagttgca ggtctcctgt gctttcccct
      181 ggaagctcaa agttaaatag atctgagttt tcagggtaca tcttagtcac gtagaaaggt
      241 tcgtcaacaa caagcagagc gtttagttcg tcctgtttgt ccaaaagtct ttccacgttg
      301 cttaccgtca ctcttccttt gaccttaagc gttttagtcg taaaagtagc cccatcgtag
      361 atgtaaccac tccttccttt gactgctcgg tgtgatacag atagtaaagg agcgctatct
      421 tcaatagcaa tattataaat accaaagtca gacaacctag ttgcctgact ctctttttct
      481 attaataaat ccaaaatact cccttctagt caaaaacaaa ataagaatct ttagattgct
      541 ctcttgattc tttttcttta acagccgtgt aaattttatc tccaacaatc tcattatgca
      601 cttcaaagat aggctctgac aattgagact gcctaacctc ttcgctaaga ttatcaagag
      661 aggtattgat tccactatta ttaactttag cagatgttga aacagtacta tttacccccc
      721 agttttgatc agtaactgct gttgcgtatg ctttacctag gctattgatc tcacctatcc
      781 actctgccat accgagggca aacccctctc cagtaaatgc acctagtgtt ttagtgacac
      841 gagatggtga gtgaatatct aaagcgcgtc taattgttgc tgctacgtta gcggcaatgc
      901 tgttagctat tgcgtagatt gtgcctgcgc tactagctag accattagca aaaccttgac
      961 ctgcataagc tcctgcagaa gacatctgcc ctgccaaagc cctgaatatt gagaggatct
     1021 tctgacaagc attattagac accgcggttg cacgagacat cccagaagcc actgcactta
     1081 caaggtttgc catagattgc tttgcagtac tgttaatgct actaaatcct gttttaaccg
     1141 cattggctat cccattcatt gaggttgttg ctgaagtctt cgccttattg aagccagact
     1201 cgaccgccga ggacaaccta ttggcgcttg aggttgcaga ggttgctgca gaagacattt
     1261 cacttgtcac gctattagac agaccagagg ctgctttagt tgagtttgac tgcattgatg
     1321 ccagactgtt actcactcct gagctcatag cttgcgcctg agaagttgca cttgtgctag
     1381 cggttcccat gtttgcacca acaccactag ctaagctgag cgtatgatta atggcgtcta
     1441 gattcattga agaagtcgca ccattaaccc ctgaagccat ttcttgagcc tgagtagtag
     1501 cgttaatatt agccacagac atattagcgc taatgccact cgcaagagac attgaatcat
     1561 tcaacccctg aagactcatc gttcctgtct gagcattaac attattagcc atctgtgt
//
LOCUS       DARYJX010000099         1618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYJX010000099 DARYJX010000000
VERSION     DARYJX010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..494)
                     /locus_tag="TU257_002039"
     CDS             complement(<1..494)
                     /locus_tag="TU257_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834995.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTITYEFIGKTSQGLKYNLSFTLRTAELP
                     FGET"
     gene            complement(506..>1618)
                     /locus_tag="TU257_002040"
     CDS             complement(506..>1618)
                     /locus_tag="TU257_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0834996.1"
                     /translation="TQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQA
                     REMASGVNGATSSMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASM
                     QSNSTKAASGLSNSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANA
                     VKTGFSSINSTAKQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAY
                     AGQGFANGLASSAGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALG
                     MAEWIGEINSLGKAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLS
                     EPIFEVHNEIVGDKIYTAVKEKESREQSKDSYFVFA"
BASE COUNT          438 a          376 c          313 g          491 t
ORIGIN      
        1 tttgtctcac cgaaaggtaa ttcagcagtt cttagtgtga aggaaagatt atattttagt
       61 ccttgactgg tttttcctat aaattcataa gtgatagtgt cgtctaagat gactttaaat
      121 ctatatttcc aaggtttatg aggagagcca ataagttgca ggtctcctgt gctttcccct
      181 ggaagctcaa agttaaatag atctgagttt tcagggtaca tcttagtcac gtagaaaggt
      241 tcgtcaacaa caagcagagc gtttagttcg tcctgtttgt ccaaaactcc ttctacatcg
      301 cttaccgtca ctcttccttt gaccttaagc gttttagtcg taaaagtagc cccatcgtag
      361 atgtaaccac tccttccttt gactgctcgg tgtgatacag atagtagagg agcactatct
      421 tcaatagcaa tattataaat accaaagtca gacaatctag ttgcctgact ctctttttct
      481 attaataaat ccaaaatact cccttctagg caaaaacaaa ataagaatct ttagattgct
      541 ctcttgattc tttttcttta acagccgtgt aaattttatc tccaacaatc tcattatgca
      601 cttcaaagat aggctctgac aattgagact gcctaacctc ttcgctaaga ttatcaagag
      661 aggtattgat tccactatta ttaactttag cagatgttga aacagtacta tttacccccc
      721 agttttgatc agtaactgct gttgcgtatg ctttacctag actattgatc tcacctatcc
      781 actctgccat accgagggca aacccctctc cagtaaatgc tcctagtgtt ttagtgacac
      841 gagatggcga gtgaatatcc agagcgcgtc taattgttgc tgctacatta gcggcaatgc
      901 tgttagctat tgcgtagatt gtgcctgcgc tactagctag accattagca aaaccttgac
      961 ctgcataagc tcctgcagaa gacatctgcc ctgccaaagc cctgaatatt gagaggatct
     1021 tctgacaagc attattagac accgcggttg cacgagacat cccagaagtc actgaactta
     1081 caaggtttgc catagattgc tttgcagtac tgttaatgct actaaatcct gttttaaccg
     1141 cattggctat cccattcatt gaggttgttg ctgaagtctt cgccttattg aagccagact
     1201 cgaccgccga ggacaaccta ttaacgcttg aggttgcaga ggttgctgca gaagacattt
     1261 cgcttgtcac actattagac agaccagagg ctgctttagt tgagtttgac tgcattgatg
     1321 ccaggctgtt actcacccct gagctcatag cttgcgcctg agaagttgca cctgtgctag
     1381 cagctcccat gttcgcacca acaccactag ctaagctgag cgtatgatta atggcgtcta
     1441 gattcattga agaagtcgca ccattaaccc ctgaagccat ttctcgagcc tgagtagtag
     1501 cgtttatatt agcgacagac atattagtgc taatgccact cgcaagagac atcgaatcat
     1561 tcaacccctg aagactcatc gttcctgtct gagcattaac gttattagcc atctgtgt
//
LOCUS       DARYJX010000100         1608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYJX010000100 DARYJX010000000
VERSION     DARYJX010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TU257_002041"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TU257_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL0834997.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TU257_002042"
     CDS             691..1080
                     /locus_tag="TU257_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0834998.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TU257_002043"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TU257_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL0834999.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          483 a          289 c          375 g          461 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYJX010000101         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYJX010000101 DARYJX010000000
VERSION     DARYJX010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            71..1468
                     /locus_tag="TU257_002044"
     CDS             71..1468
                     /locus_tag="TU257_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL0835000.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYJX010000102         1471 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYJX010000102 DARYJX010000000
VERSION     DARYJX010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1471
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..265)
                     /locus_tag="TU257_002045"
     CDS             complement(<1..265)
                     /locus_tag="TU257_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0835001.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESI"
     gene            complement(382..753)
                     /locus_tag="TU257_002046"
     CDS             complement(382..753)
                     /locus_tag="TU257_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL0835002.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            complement(765..1376)
                     /locus_tag="TU257_002047"
     CDS             complement(765..1376)
                     /locus_tag="TU257_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0835003.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQAAAGLAKVS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            complement(1380..>1471)
                     /locus_tag="TU257_002048"
     CDS             complement(1380..>1471)
                     /locus_tag="TU257_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0835004.1"
                     /translation="AEAEDEFTGAEIILIDNILEQYEANKKGE"
BASE COUNT          384 a          341 c          281 g          465 t
ORIGIN      
        1 ggatcgactc gtcccagcta tcataggccc taaaacgatc tacaatatcc gttacaacac
       61 ccggctgata ctcctcctga gtttttgtat taaatgactt acccgtccaa gagctatctg
      121 ccttgatacc aaatagagcg ttatgtgggg cgtacttgcc ccaaccactc tcaaggattg
      181 cctgtgctgc ggtcaacgat ggcaagattt tatactttgt ccagccatct aagcagcctt
      241 gcttaatgtc atctaaaaag gtcatctgtc ctccttatct aaaaacggat aaacaatcag
      301 agcaatcaca gacagcggca catatagcac tgcgattgct aggactattg ctaatcgtgt
      361 gattgctcgc atgagatcct cctatttttt actaaacata tcaataaatt gcttaaacag
      421 tgcgacatca atccccattt tgtttagatt ttctaagatt gattttagct caaagagcag
      481 atagccaacg tacatgacat acaaaaaggc tactcctgta tcatttggca gtaaaatcga
      541 caaagggata aaaaagatca tcagggcaat tgagcaaatt ttgcgcaaaa taccattaat
      601 cccctctttg ctcctaaaat caatgttggg gttaattttt gctgcaacgg tacccgttaa
      661 aaaatcaatc atcattgcga ctgcaattgc tcctaaagta aataggattt taccatcttg
      721 ggtctggatt aattgtctca aaaaaataaa catggatcac ctcactattt gcctttaacc
      781 aaatcagcgt atttaatcac tgtgacttta tcctctgatt ccagatcttt gagggtttgc
      841 ttgtcatagg taaaggcctc attgacatac acaaagacaa gattgccctc accggccaaa
      901 tcctcgtgct tgtcgtctag cacagtaaaa acgtcgtgct cctgatactg accttttttg
      961 gctggctcga taagctctag catgcctttg taaatgtcag gctcgatctt atcgacgctg
     1021 gtcaacatgt ggatagtttg caagttaatc atcttttgcg tgcgctctgc ggacacttta
     1081 gccagaccag ctgccgcttg tgcagttgtt gctgtcttag cagtttcctg cgatagtttt
     1141 tccaagtcgt ccactttttg caccgcttcg cccatggcga tttccacgta ttcggatttt
     1201 ttaaattctt ccaaggtagc tttgatgatc tctgtgtcat tagttgaggt taagtcctgc
     1261 ttgattggtt gagagatgac tgagccatcc tctgctgtaa taataacgtg agtgcttgcg
     1321 actgctcctg tgctgtcaaa ttgtgggtat tttcctgtga ctttccaatt gcgcataatt
     1381 tactctcctt ttttatttgc ttcgtactgc tctaaaatgt tgtcgattaa gatgatttcg
     1441 gcccctgtaa actcatcttc ggcctcggcc a
//
LOCUS       DARYJX010000103         1391 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYJX010000103 DARYJX010000000
VERSION     DARYJX010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1391
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            67..507
                     /locus_tag="TU257_002049"
     CDS             67..507
                     /locus_tag="TU257_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835005.1"
                     /translation="MIPKFRAFNKKTKKIYGVDGFKVSERRIYRCSLADDEFRSGRLE
                     TFHFVEDNLDDYILMQSTGLKDKNGVEVFDGDIVKCCRLFNDSLSEYVGQVKFVDFGW
                     NIVDKADTHEPFYNYKDGCPDEIREIEVIGNIYQNSELLESVEE"
     gene            504..710
                     /locus_tag="TU257_002050"
     CDS             504..710
                     /locus_tag="TU257_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835006.1"
                     /translation="MTVKELIEKLQEYPDYLTVELVLEDVDLVEAAHEADNVLSANII
                     TYDEKTLGVEQVSIDKLIISATGC"
     gene            721..948
                     /locus_tag="TU257_002051"
     CDS             721..948
                     /locus_tag="TU257_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835007.1"
                     /translation="MTKDDFLTGFVLTLLAACIFAVGFVFGSDCSSEHYEQQITDLRM
                     QLVSTQQQLKRASEDRARRTKRIAELTGNGG"
     gene            952..1095
                     /locus_tag="TU257_002052"
     CDS             952..1095
                     /locus_tag="TU257_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835008.1"
                     /translation="MIDEILKRLNKEFDNDLYNYEQERYAGYMDAIGVAIEIVEEVKR
                     GTK"
     gene            1092..>1391
                     /locus_tag="TU257_002053"
     CDS             1092..>1391
                     /locus_tag="TU257_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0835009.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFERQETFVNAFLYGYTI"
BASE COUNT          494 a          190 c          318 g          389 t
ORIGIN      
        1 tgacgaggtc atgatctatt taatcgcagt agtttgtatt ttagcattgc acaggaggaa
       61 ataacgatga taccaaaatt tagagcattt aataaaaaga ccaaaaaaat ttatggcgtt
      121 gacggattta aagtaagcga gcgcagaata tacagatgca gcttagctga tgatgagttt
      181 cgctctggtc gcttagagac gtttcatttt gtcgaggata accttgatga ttatattctc
      241 atgcaatcaa caggcctaaa agacaaaaac ggcgttgagg tgtttgatgg ggatatcgtt
      301 aagtgttgca gactttttaa cgactctttg tctgagtacg taggacaagt aaaatttgta
      361 gattttggtt ggaacatagt tgataaagca gatacacacg agccatttta caactacaaa
      421 gacgggtgtc cagacgaaat tcgggaaatc gaagttatcg gaaacatata ccagaacagt
      481 gaattactag aaagcgtgga agaatgacag taaaagaatt aattgaaaaa ttacaggaat
      541 atccagatta tctgacggtt gagttagtgt tagaagatgt tgatttggtg gaagctgcac
      601 acgaagctga taatgtgctt agtgcgaata tcataacata tgacgaaaaa acgcttggtg
      661 tagagcaagt tagcatagat aaattaatta tttcagcaac gggttgttag gaggctgatc
      721 atgactaaag acgacttttt aacaggtttt gtacttacac ttttagctgc ttgcattttt
      781 gcagtgggat ttgtgtttgg atctgactgt agtagtgagc actacgagca acaaataaca
      841 gacttgcgta tgcagcttgt tagcacgcag cagcaactta agcgtgcgag tgaggataga
      901 gcaaggcgga ctaaaaggat tgccgaattg acaggtaatg ggggataggg tatgatcgac
      961 gaaattttaa aaagacttaa taaagaattt gacaatgatc tgtataatta cgaacaagaa
     1021 agatacgctg gttatatgga cgcaataggt gtagcaattg aaattgttga agaagttaag
     1081 cgaggtacaa aatgaacatc gaagaagcga taaagtattt tgaagataag agaaaagatt
     1141 atattgtatc accaagtgta atacatgtat cgactgttga ggtcataaat attttaaaac
     1201 aaattaagtt agataaacca aagccagaaa ttccacagtt tgtcgctgac tacatagatg
     1261 atatgcacaa aaacgcacgt acattgagat acgcttttaa atacatggaa agtaacataa
     1321 aaatgcacaa atggtgtgtt tttgaaaggc aagaaacgtt tgttaatgct tttttatacg
     1381 gatatacaat a
//
LOCUS       DARYJX010000104         1316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYJX010000104 DARYJX010000000
VERSION     DARYJX010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(146..538)
                     /locus_tag="TU257_002054"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TU257_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TU257_002055"
     CDS             complement(535..1062)
                     /locus_tag="TU257_002055"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL0835010.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          423 a          330 c          254 g          309 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatacac
     1261 ccgactttat cacttgtttt agtccacacc ttactcaacc ccttggtaga gtaagg
//
LOCUS       DARYJX010000105         1303 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYJX010000105 DARYJX010000000
VERSION     DARYJX010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1303
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1091
                     /locus_tag="TU257_002056"
     CDS             <1..1091
                     /locus_tag="TU257_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL0835011.1"
                     /translation="TPKYFTDKEYWINRIEGFLKAPIISDYYPKTTSKQIKFSRREAY
                     IEPLRWKSLKNIASKNNLTTTSLLIGAYAEAIREVSLNENFTINVTRFNRPQINGKTN
                     STLGDFTNLLLLEINNSKHEKILDRFREIQGQLIEDLSHELFSGIEMQKELRKIEKDN
                     LVLMPIVFTSGIGINSWDDDERLGKIVYGLSQTPQVFLDNQVFVYNDGLKIYWDSIDE
                     ILGEDKVDLMFKKFVIFLTEIADGSFNKESTIAKKREYTDYIFSNEDIEKQEKEAIKN
                     DVVEINYIEQDMKNIWESILDISIENYDCKFFEAGGDSLRAIQLSNKIQEMFSVNVDL
                     LEIFKNPSIREISLLVSKEKENIIEGSL"
     gene            1088..>1303
                     /locus_tag="TU257_002057"
     CDS             1088..>1303
                     /locus_tag="TU257_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0835012.1"
                     /translation="MMKKVIICGTRFGQFYIEALKNIQDIEIVGILANGSERSIKCAE
                     YYRLKLFVEIDSLPKDIDFACVAVGSSV"
BASE COUNT          524 a          111 c          240 g          428 t
ORIGIN      
        1 gcactccaaa atattttact gataaggaat attggataaa tcgtatagaa ggatttttaa
       61 aggctccaat aataagtgat tattatccaa aaactacatc taaacaaatt aaattttcta
      121 gaagggaagc atatattgaa ccattgcgat ggaaatcctt aaaaaatatt gctagtaaaa
      181 ataatttaac aacaacatct ttattaatag gtgcttacgc tgaggcaata agagaagtta
      241 gtttgaatga gaattttact ataaatgtta caagattcaa tagaccacaa ataaatggaa
      301 aaacaaatag tacattaggt gactttacta atttactttt acttgaaata aataattcta
      361 agcatgaaaa aatattagac aggtttagag aaattcaagg tcaattaata gaagatttaa
      421 gtcatgagtt attttctgga atagaaatgc aaaaggagtt aagaaaaata gaaaaagaca
      481 atctagtatt aatgcctata gtatttacaa gtggtatagg aataaattca tgggatgatg
      541 atgaaagatt aggaaaaata gtatatggat taagtcaaac tcctcaagta tttttagata
      601 atcaggtgtt tgtatataat gatggtttga aaatttattg ggatagtatt gatgagattt
      661 tgggtgaaga taaagtagat ttgatgttca aaaaatttgt gatattttta actgaaatag
      721 ctgatggctc ttttaataaa gaaagtacca ttgctaagaa acgagaatat acggattata
      781 ttttctcaaa tgaagatatt gagaaacaag aaaaagaggc gattaaaaat gatgttgttg
      841 aaataaacta tatagagcaa gatatgaaaa atatttggga aagcatactt gatatttcga
      901 ttgagaatta tgattgtaaa ttttttgaag cgggtggaga ttctttgaga gcgattcaac
      961 ttagtaataa gattcaagaa atgttttcag taaatgtaga tttattggaa atattcaaga
     1021 acccttctat tagagaaata agtctattag ttagtaaaga aaaagaaaat attatagaag
     1081 ggagtttatg atgaaaaaag ttattatatg tggaacaaga tttggacaat tttatattga
     1141 agcattaaaa aatatacaag atattgaaat tgttggtatt ttagcaaatg gtagtgaacg
     1201 ttctattaaa tgtgcggaat attatagatt aaagttattt gtagagatag actctttacc
     1261 taaagatatt gattttgctt gtgtagcggt tggttcttct gta
//
LOCUS       DARYJX010000106         1288 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYJX010000106 DARYJX010000000
VERSION     DARYJX010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            85..1288
                     /locus_tag="TU257_002058"
                     /pseudo
     CDS             85..1288
                     /locus_tag="TU257_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT          392 a          309 c          242 g          345 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattt
//
LOCUS       DARYJX010000107         1273 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYJX010000107 DARYJX010000000
VERSION     DARYJX010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1273
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..414
                     /locus_tag="TU257_002059"
     CDS             <1..414
                     /locus_tag="TU257_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835013.1"
                     /translation="AMGEAVQKVDDLEKLSQETAKTATTAQTAAGLARAAAERTQKMI
                     NLQTIHVLTTSDKVEPDIYKGMLELIAPAKKGQYQEHDVFTVLDDKHEDLAGEGNLVF
                     VYVNEPFEYDKQTLKDLESEDKVTVIKYADLVKQD"
     gene            425..715
                     /locus_tag="TU257_002060"
     CDS             425..715
                     /locus_tag="TU257_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835014.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            718..897
                     /locus_tag="TU257_002061"
     CDS             718..897
                     /locus_tag="TU257_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835015.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVTSTVIM
                     SGIVCVLMNVSDIKE"
     gene            1009..>1273
                     /locus_tag="TU257_002062"
     CDS             1009..>1273
                     /locus_tag="TU257_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0835016.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPYNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEESI"
BASE COUNT          406 a          235 c          312 g          320 t
ORIGIN      
        1 gcaatgggcg aggcagtcca aaaagtggac gacttggaaa aactatcgca agaaactgct
       61 aagacagcaa caactgcaca aacagccgct ggtttggcca gggcagctgc agagcgcaca
      121 caaaagatga ttaacttgca gactatccac gttttgacaa ccagcgataa agtcgagcct
      181 gacatctaca aaggcatgct tgagcttatt gcgccggcca aaaaagggca atatcaagag
      241 catgatgtct ttacggtgct agacgacaag catgaggatc ttgcaggcga gggcaatctc
      301 gtctttgtgt atgtcaacga gccgtttgag tatgacaaac aaacgctcaa agacttggag
      361 tctgaggaca aagtcacagt cattaaatat gcggatttgg taaaacaaga ttagaggtgg
      421 ttagatgata gattttgtac aaattggtgc tttttgtggc gctgctttgt ctatcttggg
      481 tgtttgggga tttatcgtca atccctttaa aaaagccatg gaagctaacg agctagccat
      541 ggcccaactc aaagactcga tcaaggagtt agcctacgag ctaaaaaatc ttgatcgcga
      601 tagggagata accaaaaaga ttatcgatcg gcatgaggag cgtttaggac gtgtagagga
      661 cgacattatt gtcaataaag agcaaatcaa aacattattt aaaaaaggag actaaaaatg
      721 gataaatggt ttaaaaaagt agcaatcaaa acaattaaga caatggccca aaccgctgta
      781 ggggttattg gatcaagcgc attgattact gacgtcaact ggcaggtggt gacctcaaca
      841 gttattatgt caggtattgt ctgcgtcttg atgaatgtgt ctgacatcaa ggaatagcat
      901 tatgcgagca atcacacgat tagcaatagt catagcaatc acaatactgt atttaccgct
      961 atctgtgatt gctctgattg tttatccgtt tttagataag gaggacagat gaccttttta
     1021 gataagatta agcaaggctg cttagatggc tggaccaagt acaaaatctt gccatcttta
     1081 acagcagcac aggcaatcct tgagagcggt tggggtaagt atgccccata taacgctcta
     1141 tttggtatca aggcagatag ctcttggacg ggtaagtcat ttaacacaaa aactcaggag
     1201 gagtatcagc cgggtgttgt aacggatatt gtagatcgtt ttagggccta tgatagctgg
     1261 gaggaatcca tcg
//
LOCUS       DARYJX010000108         1192 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYJX010000108 DARYJX010000000
VERSION     DARYJX010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..273
                     /locus_tag="TU257_002063"
     CDS             <1..273
                     /locus_tag="TU257_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835017.1"
                     /translation="TIHVLTSGGKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKH
                     EDLAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            286..576
                     /locus_tag="TU257_002064"
     CDS             286..576
                     /locus_tag="TU257_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835018.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            579..758
                     /locus_tag="TU257_002065"
     CDS             579..758
                     /locus_tag="TU257_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835019.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            870..>1192
                     /locus_tag="TU257_002066"
     CDS             870..>1192
                     /locus_tag="TU257_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0835020.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGET"
BASE COUNT          363 a          215 c          290 g          324 t
ORIGIN      
        1 actatccacg ttttgacaag tggtggcaag attgagcctg atatctataa aggcatgctt
       61 gagcttattg agccagctaa aaaaggtcag tatcaagagc atgatgtctt tactgtgcta
      121 gatgacaagc atgaggactt ggccggcgag ggtaaacttg tctttgtcta tgttaacgag
      181 gcctttgagt acgacaagca aaccctcaaa gatctggaat cagaggataa agtcacagtt
      241 atcaagtacg ctgatttggt taaaggcaaa tagtgaggtg attagatgat agattttgtg
      301 caaataggca ctttttgtgg cgctgctctg tctatctttg gtgtttgggg atttatcgtc
      361 aatcctttta aaaaagcgct ggaggctaac gagctagcca tggcccaact caaagactcg
      421 atcaaggagc tagcctacga gctaaaaaat cttgatcgtg atggagagat aaccaaaaag
      481 attatcgatc ggcatgagga gcgtttagga cgtgtagagg acgacattat tgtcaataaa
      541 gagcaaatca aaacattatt taaaaaagga gactaaaaat ggataaatgg tttaaaaaag
      601 tagcaatcaa aacaattaag acaatggccc aaaccgctgt aggggttatt ggatcaagcg
      661 cattgattac tgacgtcaac tggcaggtgg tggcctcaac agttattatg tcaggtattg
      721 tctgcgtctt gatgaatgtg tctgacatca aggaatagca ttatgcgagc aatcacacga
      781 ttagcaatag tcctagcaat cgcaatacta tatttaccgc tatctgtgat tgctcttatc
      841 ttttatccgt ttttaggtga ggaggacaga tgaccttttt agacgacata aaaagcgcag
      901 ttatcgcaga gtggcacaat cataagattt tgccatctct gacggctgct caagctattt
      961 tagagagcgg ttggggcaag tatgccccac ataacgcatt gtttggtatc aaggcagata
     1021 gctcatggtc tggtaaatct tttgatacca agacacaaga ggagtatcag ccaggtgtcg
     1081 tgacggatct cgtggaccgc tttagagcct atgacagttg ggacgagtca atccttgatc
     1141 atggccagtt tttagtggat aatccacgat acaaatcagt tatcggggag ac
//
LOCUS       DARYJX010000109         1136 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYJX010000109 DARYJX010000000
VERSION     DARYJX010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            158..1136
                     /locus_tag="TU257_002067"
                     /pseudo
     CDS             158..1136
                     /locus_tag="TU257_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          395 a          192 c          245 g          304 t
ORIGIN      
        1 gtttctcaag aatagtatag ccgtttttct tgtattgcgc tatccacctt gaaagcatac
       61 tagaatttgg taaagcatag tctaaggacg tctgtttttg agattgaccc gcaccccaaa
      121 agttagacag aaaatctacc aatggggtgc tttttatatg aaattaagtt acgatgataa
      181 attaagaata tatgaactaa gaaaaaatgg gatgtcttgt tcccgcattg gtcaacagta
      241 tgatattcag gtttctaatc tcaaatacat ggtaaagctt atggacagat atggagttga
      301 gattgttaga aagggtaaaa ataagtatta tcctccagaa ttaaaacaag aaataattga
      361 taaagttctt cttgaaggtc agtctcaact gtctgtctct cttgagtatg ctctcccaaa
      421 tgctggtatg cttcccaatt ggatagcgca atacaagaaa aacgggtata ctattcttga
      481 gaaacaaaga gggagaccaa cgaagatggg ccgtaaacca aagaaaactt gggaagaaat
      541 gacagagcta gagcgccttc aggaagagct agaatacctt agaacggaga atgcttatct
      601 aaaaaagttg agggagcttc gtttacagga cgaagccaga gaatgagaaa ggcagaaaca
      661 attagagaga tggtccaaga aggattccga ttaaacctcc tacttgagat cgctaagatg
      721 gctcgttcaa cctattatta tcaagtcaag caattggata agtcagataa agatgaagca
      781 atcaactctg aaatcaaagc gatttatgag gagcataagg gaaactatgg ttaccgtcgc
      841 attcatttag aactcaagaa tcgtgggttt atcgtcaatc acaagaaagt gcaacgcttg
      901 atgaaagaga tgagattagc tgctcgaatt cgtcgtaaac gcaggtattc ctcttacaaa
      961 ggcgagactg gtaagaaggc tgataatctg attcaacgcc agtttgaagc tgctaagcca
     1021 tatgaaaaat gttataccga tgtgacagag tttgctttac caaacaacga tgaaaaactt
     1081 tatttagcgc ctgttcttga tggctacaac agtgagatta ttgatttcac actatc
//
LOCUS       DARYJX010000110         1072 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYJX010000110 DARYJX010000000
VERSION     DARYJX010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1072
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..317
                     /locus_tag="TU257_002068"
     CDS             <1..317
                     /locus_tag="TU257_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEL0835021.1"
                     /translation="RGDVLLRKFKAESNKINGQIKTIKNELKVVDDKKRSIKRRKDEL
                     KKFIEALFYCLEDYKSIEVDKELVDTLINRIEISKYKQVTIYFKFSFDKDIEKQLEVE
                     HE"
     gene            310..>1072
                     /locus_tag="TU257_002069"
     CDS             310..>1072
                     /locus_tag="TU257_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0835022.1"
                     /translation="MNRIAIYLRLSEEDYKKTDESVSIVNQRDYVRNYIENENSLKDC
                     EIEEYIDDGFSATNTNRPSFLRLIDNIKAGRINTIIVKDMSRFSRDYILLGDYLSNIL
                     PFLKIRFIAINDNYDSINEDGNGIDTDIQFKTLYYDLFSKELSEKVKSSFKQLKSQGK
                     NTNWAAPFGYIKDPKDKHHIILDEKTAFIVKEAFDLLLEGYSCNQVANIFNEKDYITC
                     SERKEELKISEYTRNLVTGSKINKRVWTSATISRIT"
BASE COUNT          455 a          112 c          203 g          302 t
ORIGIN      
        1 ttagaggaga tgttctttta aggaaattta aagcagaaag taataaaata aatggacaga
       61 taaaaacgat aaaaaatgaa ttaaaggtag tagacgataa aaagaggagc ataaagagaa
      121 gaaaagatga actcaaaaaa ttcatagaag ccctatttta ctgcttagag gattacaaga
      181 gtatagaggt ggataaagaa ctggttgata ccttaattaa ccgtatagaa atctcaaaat
      241 acaagcaagt aactatatac tttaaattta gttttgataa agatatagaa aagcagttgg
      301 aggtagagca tgaatagaat agccatttat ttaagacttt cagaagaaga ttataaaaaa
      361 acggatgaaa gtgtaagtat agtaaatcag agagactatg taagaaatta cattgaaaat
      421 gagaactctc tgaaggattg tgagatagaa gaatatatag atgatggttt ttctgctaca
      481 aatacaaaca gaccttcgtt tttaagactt attgataata taaaagctgg gagaataaat
      541 acgataattg taaaggatat gtcgagattt tcaagagatt atatattgct tggagactat
      601 ctgagtaata tattgccctt tttgaaaata cggtttattg ctatcaatga taactatgat
      661 tcgataaacg aagatggaaa cgggatagat acagatatac agtttaagac cttgtattat
      721 gatttattca gtaaggaatt atcggaaaaa gtaaaaagtt cttttaaaca actcaaatca
      781 cagggcaaga atacaaattg ggcagcacct tttggatata taaaagatcc aaaagataaa
      841 catcatatta tacttgatga aaagacagct tttatagtga aagaagcttt tgacttgctg
      901 ttagagggat attcttgcaa tcaggtagca aatatattca atgaaaaaga ttatataacc
      961 tgttctgaaa gaaaagaaga actaaaaatt tcagagtata caagaaatct tgttactggt
     1021 agtaaaataa ataaaagagt ttggacaagt gcgactatat ccagaataac ga
//
LOCUS       DARYJX010000111         1030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYJX010000111 DARYJX010000000
VERSION     DARYJX010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            135..1030
                     /locus_tag="TU257_002070"
                     /pseudo
     CDS             135..1030
                     /locus_tag="TU257_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          349 a          189 c          220 g          272 t
ORIGIN      
        1 ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt caaatctatg
       61 agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt attgcagaat
      121 ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt gtccaaaaag
      181 gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa gttctgattg
      241 atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct agtatgcttt
      301 caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa agaagaggga
      361 ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca gagttggagc
      421 gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa aagctgagag
      481 aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc aagaattaat
      541 cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt caacctatta
      601 ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg agctcattca
      661 aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc tggaactaag
      721 aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg tcatgggctt
      781 aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg ttggcaaaaa
      841 ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga agtgctatac
      901 cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg ttcttgacgg
      961 ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga agcaagtaca
     1021 aaccatgctt
//
LOCUS       DARYJX010000112          976 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYJX010000112 DARYJX010000000
VERSION     DARYJX010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..352
                     /locus_tag="TU257_002071"
     CDS             <1..352
                     /locus_tag="TU257_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEL0835023.1"
                     /translation="CMLMKDVKTYETVVANLGELFEEEKTYYSSVFTLFQCNLSNMKN
                     RITEESVTFESRMDWNNMTAIILLETINLLKHKKNTRYGIGEIWEMFDCCEIMEDFLR
                     EGSIELKSTSPLNL"
     gene            374..>976
                     /locus_tag="TU257_002072"
     CDS             374..>976
                     /locus_tag="TU257_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL0835024.1"
                     /translation="MDMSYLNLIFIVFIVYVILFLIFITIIHFKIFNKRIDYVNTGEL
                     FSEIDQKIVRFKGFEDINDRDLRVGTFYYPKNEERKHLILLVCGYEESYLDFKSEIFF
                     WLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNETFKKVSLVGHSMG
                     GFAVATSLQFKTNIIDNSVIISGFDYPSEFVRKSVTNISFI"
BASE COUNT          371 a           79 c          180 g          346 t
ORIGIN      
        1 atgtatgctt atgaaagatg taaaaactta tgaaacagta gttgctaatt taggagaatt
       61 atttgaagaa gaaaaaacat attatagttc tgtgtttact ttatttcaat gtaatctgtc
      121 aaatatgaaa aatagaatta ctgaagagag tgtaactttt gaatcaagaa tggattggaa
      181 taatatgacg gcaattattt tacttgaaac tataaactta ctaaaacata aaaaaaatac
      241 aagatatgga attggtgaaa tatgggaaat gtttgattgt tgtgaaataa tggaggattt
      301 tttaagagaa ggtagtatag aattgaaaag cacatcacca cttaatctat aaaatatatt
      361 aaatacatgg agaatggata tgagttattt gaatttaatt ttcattgttt ttattgtgta
      421 tgtaatttta tttttaatat ttattactat tatacatttt aagatattta acaaaagaat
      481 agactatgta aatacaggtg aattattttc tgaaatagat caaaaaatag ttagatttaa
      541 gggatttgaa gatattaatg atcgtgattt gagagtaggg acattttatt atcccaagaa
      601 tgaagaaagg aaacatttga tattactagt ttgtggatat gaagaatcct atttagactt
      661 taaatccgag atattttttt ggctgaaaaa tggatatact gtgttttgct atgatgttag
      721 aggaactgga agaagtcagg gaagaaaagt tggaggtttt actcagtttt tgaaggattg
      781 cttattgtcc attgaataca ttgaaaaaaa tgaaactttt aaaaaggtat ctttagtggg
      841 gcatagtatg ggaggttttg cagtagcgac ttcgttacaa ttcaaaacca atataataga
      901 taacagtgta atcatttcag gatttgatta tccatctgaa tttgtaagaa aaagtgtaac
      961 aaatatttcg tttatt
//
LOCUS       DARYJX010000113          958 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYJX010000113 DARYJX010000000
VERSION     DARYJX010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>958
                     /locus_tag="TU257_002073"
     CDS             <1..>958
                     /locus_tag="TU257_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0835025.1"
                     /translation="QDNQKVRLASNCLGTTRFNQVMIERGDKATDYVAPVVVEGSGES
                     TGVFKSLEEMLSGLQSINLELTDTKNSNLWSKIKLTTNGMLREYHRDHIKTEIVESAD
                     GIAKRIADDTGQKLALINETIKGIKREYQDADRQLSASYQAGIDGLKTQLANDKIGLQ
                     AEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTEL
                     ESQISGLRSVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQDAEKNYSSLTQTVK
                     GLQSTVSDPSGKIQSRFTQLQNQIDQRVTRDDVMSIINLSGD"
BASE COUNT          308 a          207 c          236 g          207 t
ORIGIN      
        1 gtcaagacaa tcaaaaagtc agattagcca gcaactgtct aggaacaact cgctttaatc
       61 aggttatgat tgagagaggc gacaaagcga ctgactatgt tgcgcctgtt gtcgttgagg
      121 gcagcggtga gtcgacaggt gtgtttaaaa gtcttgagga gatgcttagt ggtctacagt
      181 ctattaattt agagctgaca gataccaaaa actccaatct ttggtcaaaa atcaagctca
      241 cgacaaacgg tatgttacgc gagtatcatc gtgatcatat taaaacagag attgttgaga
      301 gcgcagatgg tattgccaag cggattgccg atgacactgg ccaaaagctg gcactaatca
      361 atgagaccat caaaggtatc aagcgtgagt accaagacgc agatagacag ctatccgcga
      421 gctaccaagc gggcattgat ggcctaaaaa ctcaactggc caatgacaaa atcggtctac
      481 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
      541 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
      601 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcgcact gagttagagt
      661 cgcagattag cgggttaagg tctgtgcagc agtcaactgc aaaacaaatc tcgcaggaga
      721 ttagagacag gacaggtgct gttagtcgtg tgcaacagga cttagccagc tatcaaagac
      781 gcttgcagga cgccgaaaaa aattacagca gtttaaccca gacggttaaa ggtctacaat
      841 caactgttag cgatccgtca ggtaaaatcc agtcgaggtt tacacaacta caaaatcaaa
      901 tcgaccaacg tgtgacaaga gatgacgtta tgtcaatcat caacctatcc ggagatag
//
LOCUS       DARYJX010000114          953 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYJX010000114 DARYJX010000000
VERSION     DARYJX010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..105)
                     /locus_tag="TU257_002074"
     CDS             complement(<1..105)
                     /locus_tag="TU257_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0835026.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLL"
     gene            complement(114..>953)
                     /locus_tag="TU257_002075"
     CDS             complement(114..>953)
                     /locus_tag="TU257_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0835027.1"
                     /translation="AGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFN
                     IDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYI
                     NGL"
BASE COUNT          252 a          214 c          201 g          286 t
ORIGIN      
        1 aagcagctta gcgcggccgc gattaactct catgttagta accttaattt tgtctagtac
       61 gctatagagc gtatttaagt ctttgttttg tactgttaaa tccatgttgt ctcctataat
      121 ccattaatat atgagttata ctctctgatg attgcactag tagtgtctga gttaaaggtc
      181 cacgctgtat tattagcgtg tagccagcag cggccaagag ctaaaatggc ctgatacatc
      241 ttattgagat cgaccatttt tggcattagg ctaggccgca tcttaaagcc acgatcgatg
      301 ttaaaatcgt cgctaaagac aatatcatca ccgtaaattt cggcctgatc gacaagcgct
      361 gtgtgctcgt aacctcgcgc atacctaaaa aacctagcac cgcaaaaacg accgctcgac
      421 gcgctgttaa tcccgtcacc tgacgatgtt atcccgatcg aggcgtaaag cgcactacct
      481 gtataatttt ttggcgtggc attgctaaaa tgcacaaagg ctgtgtgggt accgtcttta
      541 cgtaccaaag cgttgtcttt gttattaaag ttaatggtag cgttgctgtt aaagtcaatc
      601 ttagagtttg acaagtcaat catcatcgct ccgttgcgag ctctgataac tttgccctcg
      661 agcaaacttg tgatcgtatg ctcgattttg gccctgataa aattagcatc taagccgaca
      721 atgctgctag cgtttagatt aatgatacga gcctttgagg catctaaagt acctgcgata
      781 atctgatcag ccttgatttt gatagcctcg gctatcttag tggtaaaagt gccattgacc
      841 gttgtattgc catcaagagc gatgtgttta cctgcaatga ctgcgccata cgtattgaga
      901 ttaatcgctg agataatctc gctgccagac attttagcat caatcccacc agc
//
LOCUS       DARYJX010000115          908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYJX010000115 DARYJX010000000
VERSION     DARYJX010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(7..492)
                     /locus_tag="TU257_002076"
     CDS             complement(7..492)
                     /locus_tag="TU257_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL0835028.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(581..654)
                     /locus_tag="TU257_002077"
     tRNA            complement(581..654)
                     /locus_tag="TU257_002077"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Arg,seq:acg)
BASE COUNT          274 a          261 c          137 g          236 t
ORIGIN      
        1 ccccttttat ttctcaccag taaagtcctg aaagtaaggt cctatcttgc gaagcaaggc
       61 ccgtctcccc tcaaaccgct ctcccctgat caaagcccga aactgcgaca gctcaccctc
      121 tgtcaatcgc tcctcaacct ccttcacaat caactgataa gccacataat catctactcc
      181 caaaccacct gctggtatcg catggcctac cgacccaatc tcctcataag ccatcttatg
      241 aaaccgacgc ttctgactct cctgctgccg caacacgtcc ttcaaataag aggaaaactt
      301 ggtcttaaaa taacgatata gcttctcctc atcctctatc aattctggat aagtgaccaa
      361 taaccgatac aagatcaacc gcccctcctg taaccaatca tctagctccc acagctgaat
      421 ataataatgc tgtcttagct tcataataat aggcttgatc ttatcaaaca acctcactaa
      481 atcatcagtc attatacttt ctccttttca tgcttagtag ccttattata aggagacaaa
      541 caaaaaaaca acaggacaga aatgtcctgt tgccttgcta tgcaccctag aggagtcgaa
      601 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgcttttct
      661 taactattac tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat
      721 aggtaagtcc actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa
      781 ctgatcctct ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact
      841 ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      901 agctatgg
//
LOCUS       DARYJX010000116          846 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYJX010000116 DARYJX010000000
VERSION     DARYJX010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(107..622)
                     /locus_tag="TU257_002078"
     CDS             complement(107..622)
                     /locus_tag="TU257_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835029.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
BASE COUNT          261 a          150 c          137 g          298 t
ORIGIN      
        1 tacatgtgtg tgaaacacaa aaaaccgccc agaaataatc tgagcggttg atttttattt
       61 tggctaattc ttactatggt aattggttca tgattgtgcg agggtgtcaa cgaagataat
      121 cggcatcggt aatgcttttt aatctgtcgg tatagtttgg gaatgtagag aatttgaaac
      181 gtttaggatc tgttaattta tgttgatcac tattagctac agcttgatta taatctatga
      241 tagcctttat caacttgtta acaataagta tatcattatc aacaatctta aaataatcaa
      301 cctgctctcg taatttgaac gttctgttta aaatatattt tggatcttca accactagag
      361 ctttgccaat atcaagcccc tctacgcatc cgtatttttt agagtctctt aatttatatt
      421 ttagttgata ttttttagga atattacttc tcaaagggat tgcaaaagtt agattttgga
      481 tacttaccaa cacaatggca aaacctcggc ctttgttata tagcttcttc tctttaaaat
      541 catagtctaa agcttgtacc aaatcgaaat ctcgacacat gtttaaatca atctgaccga
      601 atactaattt tttactcttc attatttgcc ttctaaaaat aaaaaatcct accaactggg
      661 tattggtagg acgcattgcc aacgggatac ttctgttaac gagcgcgtcc ctccgccccc
      721 tcattgccaa aatggcgaga gtttaacgac atggaaaggt cggaacatag agataatgct
      781 tttactattt atgttcattt acattattac ataatatgtt gcattcgtca aatatagaat
      841 ctttaa
//
LOCUS       DARYJX010000117          828 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYJX010000117 DARYJX010000000
VERSION     DARYJX010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..221
                     /locus_tag="TU257_002079"
     CDS             <1..221
                     /locus_tag="TU257_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HEL0835030.1"
                     /translation="HFLTCFIALVHLRLLQHQIDWQMSPERIITALNSAKVTPLQDNY
                     YRLQESLDMQELNRLLGIEWAKGIVQCQ"
     gene            395..>828
                     /locus_tag="TU257_002080"
     CDS             395..>828
                     /locus_tag="TU257_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0835031.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          310 a          156 c          190 g          172 t
ORIGIN      
        1 ctcactttct aacctgtttc attgctttag ttcatctacg cctccttcaa catcagatag
       61 attggcagat gagtcctgaa cgtatcatta ctgccttaaa cagtgccaag gtaacaccgt
      121 tacaagataa ctactacaga cttcaagaaa gccttgatat gcaggagtta aacagactgc
      181 taggaattga atgggcgaag ggaatcgtac aatgtcaata acatcaatca aaaatcagac
      241 gattaggatt ttgattaaaa aaaaaaaaaa acgaaaccaa agattgaaat tgatagatag
      301 ctattcccac tctaatagtg gacatgttag aatttccttt gggaaaggaa gttacaggaa
      361 actaagactg tttctaccac aaaaggagag aaagatgaga tacacattaa acaaaaacaa
      421 gcgtgctcgt aactacgggc tatgctcagc agctatcgct ctagcagcag tagccagcct
      481 aggaacagct ggcagcgcta aagctgagga agcaaaaaca ttagaccaac tacctaatcc
      541 agaagagcaa attctatata attattggga cacaaatgat cagaaagcaa gagaatatct
      601 tggagaccta tacggtttcc taaaatctta tttaggagag ttggaaaaaa aagctaaaga
      661 gcctggacct gctggaccta aaggtgaaaa aggcgaaaaa ggcgaaaaag gcgagaccgg
      721 tccgatgggg cctcaaggcc taaagggtga ggacggaaaa gacggcgcac ctggagaaaa
      781 aggagaaaaa ggtgatccgg gtatccaagg ccctaagggg gaaaaggg
//
LOCUS       DARYJX010000118          804 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYJX010000118 DARYJX010000000
VERSION     DARYJX010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..243
                     /locus_tag="TU257_002081"
     CDS             <1..243
                     /locus_tag="TU257_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HEL0835032.1"
                     /translation="NKAFYEEYKSQIIAYETAMKSLKNSKLQTLSIKNLSDKYMLLEQ
                     EKTTLMGEYSSQNSMLRKLQQAKKNTDLYLDNSLEK"
BASE COUNT          317 a          135 c          107 g          245 t
ORIGIN      
        1 aacaaagcct tttatgaaga atataaatca cagatcatcg cctatgaaac agctatgaaa
       61 agtcttaaaa attcaaagct tcaaacattg agcattaaaa atttatctga taaatatatg
      121 cttttagaac aagaaaaaac tacacttatg ggagaatatt cctctcaaaa ctctatgctt
      181 cgcaagctgc aacaagcaaa gaaaaataca gatttatacc ttgataacag ccttgaaaaa
      241 taaaaaaaag aaggagatta tccctaccca tatttcaggt aagaataatc tccttacttg
      301 ctctcaaatt gataaaagta tattttctac aatatttcac aataatattt tcttatttgt
      361 cgtgtgtttc tacaagatag tcctctcttc ttttccacac aaccaaagaa ataatagcga
      421 ttataatata attgaccact tgattcataa agctgttgtt taaaagtggc agaaaatagg
      481 atttttcagt tgtaataaat ccattcacca ggaggcaata tacaatcata gagctaaaaa
      541 atgaaatagc taaatttaag attttcccta acactctaaa ttttttgtgt atgaactgaa
      601 atagaataga atatattatt actaccaata ttgctgccag aatatcccaa aaatatatag
      661 catatccgga tgagaatttc actgaaaagt agtggtgggt atagtaccag cttgctataa
      721 ataccacaag tttatccagt gcaaacaggc taatttttac aaatgttgct cctgcaaata
      781 gaatgactcc caaatatagt ataa
//
LOCUS       DARYJX010000119          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYJX010000119 DARYJX010000000
VERSION     DARYJX010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU257_002082"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU257_002082"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL0835033.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYJX010000120          720 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYJX010000120 DARYJX010000000
VERSION     DARYJX010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>720
                     /locus_tag="TU257_002083"
     CDS             <1..>720
                     /locus_tag="TU257_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0835034.1"
                     /translation="KSVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWD
                     KEALKTNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDL
                     WGNAIDLLNSAAAQGLEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIK
                     TVEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETS
                     KTGTFTLDAAEINVRRWPNLTS"
BASE COUNT          211 a          142 c          186 g          181 t
ORIGIN      
        1 aaatcagttg tcggggagac tgactataaa aaggcttgtc atgcaataaa agcagccggt
       61 tatgccactg caagtgatta tgcggagctg cttatccagt tgattgagga aaacaacttg
      121 caaaaatggg ataaggaagc cttaaaaact aataaggagg taacgatgac aaccgcaaat
      181 gagattgtac aatactgtgt tgaccttgcc aactcaggta tgggagttga taaagatggc
      241 tgttttggga cgcagtgtgc ggacttgcca tgttttatcg tcaaaaactg gttcgggatt
      301 gacttatggg ggaatgcgat tgacctgtta aacagtgcag cagcgcaagg tctagaggtt
      361 atctataacg cacctggagt taatccaaaa gctagtgact tatttgtcat ggaggtagct
      421 ggcagtcctt atggacacac aggagctgtt attgaggaca gtgatggcta taccattaaa
      481 actgttgagc aaaacattga cggcaactgg gacagtttac aagtaggtgg ccctgctcgc
      541 tttaatactc gtgactttac tggcgttgtc ggctggatta ggttacctgt tgaccatact
      601 aaccagacag tagatacagc accgcaaacg tctgacacca tcgtggagac gtcaaaaacg
      661 ggtactttta cacttgacgc cgcagagatc aacgtccgcc gctggccgaa tttaaccagt
//
LOCUS       DARYJX010000121          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYJX010000121 DARYJX010000000
VERSION     DARYJX010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>672)
                     /locus_tag="TU257_002084"
     CDS             complement(<1..>672)
                     /locus_tag="TU257_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL0835035.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYJX010000122          607 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYJX010000122 DARYJX010000000
VERSION     DARYJX010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..604
                     /locus_tag="TU257_002085"
     CDS             <1..604
                     /locus_tag="TU257_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0835036.1"
                     /translation="DVLNYNKIRDVDIFNRILSFAIENIGSTFSANSIKKYLKNESRG
                     VSVDTILNYLEYCNRAFILKKVQRFDTVGKKKLKVDEKYYLTDHGFRQARGYSNTKDI
                     ERTLENIVYIELVSRGYRVEIGKVKDLEIDFIASKDNERLYYQVSYLMETEETRKREF
                     GVYDFVRDNYPKFVLSMDKVDFSQNGIIHKNVIDFLLESK"
BASE COUNT          236 a           54 c          120 g          197 t
ORIGIN      
        1 agatgtgctt aattataata agatacgaga cgtagatata tttaacagga tattatcttt
       61 tgctattgaa aatatcggat ctactttttc cgccaacagt ataaaaaagt atttgaaaaa
      121 tgagagcaga ggagtatctg ttgatacaat tttaaattat ttagagtatt gtaatagagc
      181 tttcatacta aaaaaagtac aaagatttga tactgtagga aaaaagaagt taaaggttga
      241 tgaaaaatat tatcttacag atcatggatt taggcaggca agaggatact ccaatacaaa
      301 ggatattgaa agaacattgg aaaatatcgt ttatattgaa cttgtttcaa gaggatatag
      361 agttgaaatc ggcaaagtaa aagacttgga aattgatttt attgcaagta aggataatga
      421 aaggttatat tatcaggttt cttatttgat ggaaacagaa gaaacaagaa aacgagagtt
      481 tggtgtgtat gattttgtta gagataatta tcctaaattt gtcttatcca tggataaagt
      541 ggattttagt caaaatggaa ttattcacaa aaatgtgatt gactttttat tggaaagcaa
      601 gtagttg
//
LOCUS       DARYJX010000123          575 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYJX010000123 DARYJX010000000
VERSION     DARYJX010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>575)
                     /locus_tag="TU257_002086"
     CDS             complement(<1..>575)
                     /locus_tag="TU257_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0835037.1"
                     /translation="AGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLNSAKMDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT          159 a          148 c          110 g          158 t
ORIGIN      
        1 gcatacctaa aaaacctagc accgcaaaaa cgaccgctcg acgcgctgtt aatcccgtca
       61 cctgacgagg ttatcccgat cgaggcgtaa agcgcactac ctgtataatt ttttggcgtg
      121 gcattgctaa aatgcacaaa ggctgtgtgg gtaccgtctt tacgtacaag cgcattgtcc
      181 ttgttgttaa agttaatggt agcattgcta ttaaaatcca ttttagccga gtttaaatca
      241 atcatcatcg ctccgttgcg agctctgata actttaccct caagcaaact tgtaatcgta
      301 tgttcaattt tagccctgat aaagttagca tctaagccga caatgctgct agcgttaaga
      361 ttgatcactc taatcttagc agcgtcaatc gtaccaccaa tgatttgatc agctttgagc
      421 ttaataaact caccgagctt agccccaaat gccccattga cggtcgtatt accgtccaga
      481 gcaatacgct cgccagagat ccgcacgcca tagccattaa gatttatcgc tgagataatc
      541 tctttagcgc tcatcttagc gtcaatacca ccggc
//
LOCUS       DARYJX010000124          563 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYJX010000124 DARYJX010000000
VERSION     DARYJX010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>563)
                     /locus_tag="TU257_002087"
     CDS             complement(<1..>563)
                     /locus_tag="TU257_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0835038.1"
                     /translation="ELLIQLIEQNDLQKWDAEALAKRKESQMISSQCREVIEFYINLA
                     NAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASAQGWEVHRMPTDAN
                     PRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNADALYVGGPARFNTR
                     DFTNVAGWFYPPYQGDVAAQTVSTDPQT"
BASE COUNT          148 a          157 c          114 g          144 t
ORIGIN      
        1 gtttgcgggt ctgtgctgac cgtttgtgca gcaacatctc cctgataagg aggataaaac
       61 cagccggcca cattagtaaa gtcacgagta ttaaaacggg ccggaccccc tacatacaac
      121 gcatctgcat taccatcaat attttgctcg atagtctgca tagtgtaacc atctgagtca
      181 acgtacacaa gacccgtatg accataattg ataccaccaa accaagcgtc catgacaaaa
      241 aatgccccag ctcgtggatt tgcatctgta ggcatgcgat ggacttccca gccctgcgca
      301 cttgcgctat ctagtaagtc cgctgcgttg ccccagagat cgacaccaaa ccagtgctta
      361 gctgcgtaac aagggacatc tgcacattgc gtgccataag ccccgtcctt atcaacaccc
      421 ataccagcat tagccaaatt gatgtaaaac tcgataacct ctcgacactg cgaactaatc
      481 atttgtgact cctttctttt tgctagggct tccgcgtccc atttttgtag gtcgttttgc
      541 tctattagtt ggataagcag ctc
//
LOCUS       DARYJX010000125          562 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYJX010000125 DARYJX010000000
VERSION     DARYJX010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..379
                     /locus_tag="TU257_002088"
     CDS             <1..379
                     /locus_tag="TU257_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0835039.1"
                     /translation="GFRRGETYTISFSQTCELLKKVAITLTQANNKGVKLVLTPTKAK
                     MEAQTFNLSKDKEVISVYPLSYRAALTGDWYKSKQVDLNAAEVQNLALEMAYRDVVDS
                     NNASLVLDWSENPDVIFDGNGGS"
     gene            379..>562
                     /locus_tag="TU257_002089"
     CDS             379..>562
                     /locus_tag="TU257_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0835040.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGP"
BASE COUNT          176 a           99 c          140 g          147 t
ORIGIN      
        1 tggttttaga cgcggcgaga catacacgat tagctttagc cagacctgtg agttgctcaa
       61 aaaagtggct atcacgctga cgcaagctaa taataaggga gttaaactgg tactgacacc
      121 taccaaagct aagatggagg cgcagacctt taatctaagt aaagataagg aggtcatcag
      181 cgtctatcct ttgagctaca gagccgcttt aactggtgac tggtataaat ctaagcaagt
      241 tgacttaaat gcggcagagg tccaaaattt ggctctggag atggcttata gagacgtagt
      301 tgatagcaat aatgctagtt tagttttgga ttggtcagaa aatccagatg ttatttttga
      361 tggaaatgga ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg
      421 acaaaaaacg agtgggagtc tagtgacatc attttgccac aaggccagct cgtctatgag
      481 tctgacacag gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat
      541 caaggtgggc caccaggtcc cc
//
LOCUS       DARYJX010000126          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYJX010000126 DARYJX010000000
VERSION     DARYJX010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(68..139)
                     /locus_tag="TU257_002090"
     tRNA            complement(68..139)
                     /locus_tag="TU257_002090"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYJX010000127          418 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYJX010000127 DARYJX010000000
VERSION     DARYJX010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>418
                     /locus_tag="TU257_002091"
     CDS             <1..>418
                     /locus_tag="TU257_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL0835041.1"
                     /translation="KLASSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSG
                     IKHSSSVGGAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGK
                     TNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRG"
BASE COUNT          142 a           77 c           91 g          108 t
ORIGIN      
        1 ccaaattagc atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
       61 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctacggctta
      121 aacctaatag tggtattaag cactcatctt ccgtaggagg agcgattaac attgatatgt
      181 ctaaatcaac aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      241 tgatgatttt acgctctgac aaagatacgt ttgatcagtc agctcaattt gtggattaca
      301 gcggtaagac taatgctgta aatattgtaa tgcgccagcc aagcgcacct aatttttcct
      361 cggcacttaa tataaccagt gccaacgaag gcggtagtgc gatgcaaatt agaggcat
//
LOCUS       DARYJX010000128          417 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYJX010000128 DARYJX010000000
VERSION     DARYJX010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>417)
                     /gene="glmU"
                     /locus_tag="TU257_002092"
     CDS             complement(<1..>417)
                     /gene="glmU"
                     /locus_tag="TU257_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL0835042.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGR"
BASE COUNT          103 a          133 c           81 g          100 t
ORIGIN      
        1 cgccctatag ccacactgtc tgccggcact gactgggcta tcgtagaccc tgcggctgtt
       61 aaagcattct ccccaacctc tactggagct atcaaagtcg aatgactccc aataaaagcg
      121 tgatcgccaa tcactgtctg gtatttccgt tgaccatcat aattaaccgt aatgcttcct
      181 gcaccaatat taacctctga gccaatctcg gcattcccca ggtaagtcaa atgccctgcc
      241 ttggtattgg cccctagatg agacccctta acctctacaa agttcccaat atgaacgctc
      301 tcatcgagct gggagtctgg gcgaatgtgc gcatagggcc ctactgtcac accatctgct
      361 aggactgaat cctcaatcac tgactggctc accactacgc cctcaccaag cctcgaa
//
LOCUS       DARYJX010000129         3704 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848936-rid18538743.guided.078, whole genome shotgun sequence.
ACCESSION   DARYJX010000129 DARYJX010000000
VERSION     DARYJX010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848936
            Sequence Read Archive: SRR25004213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787558.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787558.1
            Genome Coverage       :: 126x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:01:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 33 of 81
            Pseudo Genes (incomplete)         :: 30 of 81
            Pseudo Genes (internal stop)      :: 27 of 81
            Pseudo Genes (multiple problems)  :: 9 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3704
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848936-rid18538743.guided.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2021-02-19"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            269..1990
                     /locus_tag="TU257_002093"
     CDS             269..1990
                     /locus_tag="TU257_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0835043.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            1992..3155
                     /locus_tag="TU257_002094"
                     /pseudo
     CDS             1992..3155
                     /locus_tag="TU257_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            3307..>3704
                     /locus_tag="TU257_002095"
     CDS             3307..>3704
                     /locus_tag="TU257_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0835044.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPS"
BASE COUNT         1096 a          629 c          846 g         1133 t
ORIGIN      
        1 aaaaaaggct ttacaagccc agtattctat gataagatgt taggcagatt aaaagaaagg
       61 agaaattaat aatgatccgt ttcattcaac tatttaacca ttattacgat agtctccttt
      121 ctaaccaaaa cagttagttt cttttagttt cactaaatag aaatagtaga gcccgcggta
      181 ggaaggatat cttattgcgg gctttttgtg tgcaaaaatc ctattttaag acagcttgaa
      241 ataggttagt tcagaaatgg aggatatgat gctgacctta attgttcaac atattaagca
      301 aaagaaatgg atttatatcc ttattgcaat gactttagtg atatatgatg cctcacttgt
      361 gataccaaca agggttattc aagacttggt tgatttgatg tcaaggcatc agctaagctc
      421 aggggcattg gtgaggcatg ttatcattct tttggctacg gcagtagtgt cttatggggt
      481 tgcttatttg tggcatcttc atttatttca ggaggcagtt cattttaagt ttgatattca
      541 gcagcgtgcc tttcgaaagc ttgtttttat gagaacgcct ttttatgaga aatttcgctc
      601 aggtgacatg atcacgcgtt tttcaacaga tgtcgaagca cttatggacc ttatcggcta
      661 tggcttgatg attatcctat atgctggtgg tatgattgct tttattattc cgaccatgtt
      721 tttgatttct tggaaaatga ccttgatagg aatagtaccg attttgctta tgatggtgat
      781 gatctatggt gtgacgaaaa agcaagagca tttggttgaa gaggcgcgtg aggcgatttc
      841 aagccttagt gatgaggtac tagaaaccgt tgagggcatt agagtgatgc gtgcttacag
      901 taaaaaagat tatttggcac ttcattttgc tcaaaagact cagaatttgg cagataaatg
      961 gaatcaggtg gccaagtatc gtgccttgta ctttcctctt tacagcgtca tgattgccat
     1021 tagtacagta atcattttaa tggtaggcct acagctcata gcaagctcag aggtaacact
     1081 tggtcaagtc attgcgctgc agctttatct ggtgtctttg gtggagccct ttggcatgct
     1141 gtcagacttt attttggttt atcagacagg aaagacctct tttggtaaga ttaatgaact
     1201 catcgaaaca agtgatgata tggagcctga tggccagctt gagttagaga gctttgatca
     1261 gattgctttt atagactata gctttaccta tgccaatagt tctaggccta gcttagaaaa
     1321 gatcaattta accctgaaaa agggacaaac cttagggatt gttggtaaaa caggctctgg
     1381 taaaacaacc cttgtcaggc agtttttgag acaataccct cttgggcagg ggcagctgat
     1441 gattaatcat cgtagtgtct tggattataa gcgtcaatca cttgagcgtc aaattggcta
     1501 tgtgccacag gagcatatcc tgttttcaaa aacggttgct caaaacattg cgatggggaa
     1561 aaaggcagct acaactgagg aaatcttgga ggcgattgaa actgcggcct ttacgcgtga
     1621 tgttcaagga atggcaaagg gcttggatac tgagattgga gagcgtggtc tgtctatttc
     1681 aggaggtcaa aagcagcgta tttcgattgc cagagccttt ttgtcccagc cagatttgct
     1741 gattttagat gattccctgt cggcagttga tgctagaaca gagactgata ttattcgaca
     1801 cattcaagac gaaagaaagg gaaagacaac acttattgtt agccatcgct tgtctgcgat
     1861 tcagcatgcc gattgggtta ttgttctgga tcaggggcag atagtagagg aaggtcagcc
     1921 ccaacaactt ttagctcaga agggctggta ttatgaacag taccagcgtc agcaggctca
     1981 ggaggtttaa gatgacccta tttataaaat taataaaaga aattaaagct gtgaccttgg
     2041 ctttttccct ggcaataggc tttttgctag tggcaacagc tggaggtcag atggctccct
     2101 tattgttgca acaaacgatt gatcattact tgactccgat agctagagga aaagaggtac
     2161 cgattgaagg ctttcagcgc ttgctcctgc tgtatttgct gttaattgtg ataacagcag
     2221 ttttgcgtta tatctcttat cgaatgctgg tttattcctc taataggatc gttgctaatc
     2281 ttcgtaatcg agcctttgat gtcatgcaga ggctgccgat agcttatttt gatcatcagc
     2341 ctgcaggaaa gattgcaact aggattgtta atgatactga aaccctgaag aatcaatttt
     2401 atgataacct tttgtctcaa attattgtca gtctttcaca aattattttt atttatgtgg
     2461 tgatgattta ccttgatgtg aagtcaggct tgctgttgct gcttattatg ccactctttt
     2521 atggcatgca atggctgtat aaaagcttga ctgaccagcc aatgaaggat ttttatcagg
     2581 ctaggagcgc tgtcaacaca caagtcaacg aaaccatgaa tggtgtttct attattcagc
     2641 tttatcatca agaggatacg atcttagagg aatttgaaga gcagatccac cagatgaaaa
     2701 cagctgatga taggattatt tttgcagagt cagttgcttc atggaccctg acggaattgg
     2761 taaagtatgg catgattgcc gctattttgg ctgttattgg ttaccagttc ttgcagggga
     2821 gatcaggcat cacagttggt aagctcttta tttacgtcaa ttatttgctg cgcttgtttg
     2881 atttattaag tatgctggtt aggcagctac ctaatattca gcgctcaaca gcgacaggaa
     2941 cgcgcctaat gaagctgctt gaggcgcaga cagagccgga taaagcacga gcaattgagc
     3001 taacagatgg tactgtggat tttaccaagg tgtattttgc ttacgaaaat ggcaagacag
     3061 ttttatctga tattaccatt catgctgata aaggggagac ggttgcccta gtagggcata
     3121 ctggctctgg ggacaatgct ataatgatga tagtacaata aatccaagta aaatcaatgg
     3181 ttaaaggctt ccgcaaaact tttaaacttg atgatggatt gaggctatca tcttttttta
     3241 tatctaaaat tatataaaag tatagcataa aatgaaatct ctgtatagag aagaaggagg
     3301 gactttatgg cagaagtgat aaccatagcc aatcgaaaag gcggagttgg aaaaacaact
     3361 acaactctaa accttgccta ttcactaaaa gaactgggga aaaaagtatt agtcattgac
     3421 cttgatccac aagctaatct tacaagatgt tttgatatgg gaaatacaga aaatataaaa
     3481 accatagggc atttgttaat ggtagaactg gaggaagaag aaagctattt ggtagagggc
     3541 tataccaaat cttatgatga gatagatatt atcccctcaa gcattttctt atccgccgtt
     3601 gaaacacaaa tgagagcaga aacaggaagt gaacgtatat tatcggaaat tattaggagg
     3661 gtaaaagaga attatgacta tattctcata gatacatcac catc
//
